Gene Overview
Target Gene: GAB3
NCBI Official Symbol: GAB3
Entrez ID: 139716
Ensembl ID: ENSG00000160219
Gene Full Name: GRB2 associated binding protein 3
Strand: -
Gene Locus: Xq28
External Links:

GAB3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate GAB3   
T(co)Fs that Repress GAB3
The Intensity of the Gene Regulated by T(co)Fs:
GAB3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
GAB3 HOXA1 siRNA Lung_fibroblast IMR-90 0.62113 -0.68703 0.09999 0.34289 DataSet_01_110
GAB3 ID1 siRNA Lung A549 1.64894 0.72154 0.15457 0.3886 DataSet_01_117
GAB3 ID1 siRNA Lung H1650 2.37663 1.24892 0.00157 0.32206 DataSet_01_118
GAB3 ZIC2 siRNA Pancreas PANC1 4.31907 2.11072 - - DataSet_01_121
GAB3 FOXM1 siRNA Central_nervous_system U87 2.61395 1.38623 - - DataSet_01_122
GAB3 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.03168 1.02268 0.1053 0.99993 DataSet_01_138
GAB3 ELK1 siRNA Peripheral_blood CD4+ T cells 1.57634 0.65658 0.02699 0.10259 DataSet_01_162
GAB3 JUN siRNA Peripheral_blood CD4+ T cells 1.65234 0.72451 0.00219 0.02589 DataSet_01_164
GAB3 TP53 siRNA Lung SAECs 2.06 1.04264 0.05087 0.40782 DataSet_01_175
GAB3 CREB1 shRNA Parotid_gland H3118 MEC 4.31994 2.11101 0.73869 0.89846 DataSet_01_194
GAB3 TP63 siRNA Immortalized_keratinocyte HaCaT 0.52715 -0.92372 - - DataSet_01_200
GAB3 HIC1 shRNA Mammary_gland HBL100 2.05098 1.03631 - - DataSet_01_205
GAB3 KLF2 shRNA Bone_marrow RPMI8226 0.19168 -2.38324 0.00443 0.41835 DataSet_01_226
GAB3 FOXA1 siRNA Prostate LNCaP 1.80552 0.85241 0.07041 0.34874 DataSet_01_233
GAB3 TWIST1 shRNA Stomach CAF32 0.44195 -1.17803 0.00095 0.01928 DataSet_01_253
GAB3 TWIST1 shRNA Stomach CAF 0.54405 -0.8782 0.01624 0.52717 DataSet_01_254
GAB3 STAT5 shRNA Prostate CWR22Pc 1.65425 0.72618 0.13934 0.29524 DataSet_01_279
GAB3 ESRRA shRNA Embryo_kidney 293T 1.53665 0.61979 0.54352 0.90592 DataSet_01_280
GAB3 POSTN shRNA Brain GSC272 3.11027 1.63704 0.1729 0.58498 DataSet_01_293
GAB3 TFAP4 siRNA Brain BE(2)-C 0.19108 -2.38776 0.34665 0.51625 DataSet_01_295
GAB3 PTEN shRNA Skin A431 0.40325 -1.31025 0.05317 0.19011 DataSet_01_301
GAB3 PTEN shRNA Mammary_gland SKBR3 1.68069 0.74905 0.0794 0.59771 DataSet_01_303
GAB3 SOX9 siRNA Prostate VCaP 0.4537 -1.14018 0.14252 0.9316 DataSet_01_308
GAB3 SOX9 siRNA Prostate VCaP 0.4537 -1.14018 0.14252 0.9316 DataSet_01_309
GAB3 ARNT siRNA Upper_aerodigestive_tract HSC3 0.63338 -0.65885 - - DataSet_01_315
GAB3 GATA3 siRNA Oral_cavity OEC-M1 0.63315 -0.65939 0.3133 0.99787 DataSet_01_347
GAB3 ELK1 siRNA Mammary_gland MDA-MB-231 2.13443 1.09385 - - DataSet_01_354
GAB3 PAX3 shRNA Soft_tissue Rh30 0.36801 -1.44217 - - DataSet_01_359
GAB3 RBM17 shRNA Liver HepG2 0.5 -1 0.13806 0.40479 DataSet_02_100
GAB3 SSB shRNA Liver HepG2 0.5 -1 0.05926 0.09831 DataSet_02_107
GAB3 PRPF4 shRNA Liver HepG2 4 2 0.00609 0.04268 DataSet_02_128
GAB3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52421 -0.93179 0.00299 0.03105 DataSet_02_131
GAB3 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58913 -0.76335 0.06163 0.26331 DataSet_02_144
GAB3 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.75307 0.80988 0.00516 0.23369 DataSet_02_152
GAB3 ZFX siRNA Prostate C4-2B 9 3.16993 0.32952 0.44575 DataSet_02_172
GAB3 ATF4 siRNA Skin A375 0.656412 -0.607328 0.243618114551777 0.775512819201899 DataSet_03_018
GAB3 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.627179 -0.673051 0.171758886948571 0.800346763345071 DataSet_03_025
GAB3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 3.22168 1.68781 - - DataSet_03_096
GAB3 GATA4 siRNA Stomach KatoIII 0.639559 -0.644851 0.501269790442807 0.964576946352793 DataSet_03_106
GAB3 GATA6 siRNA Stomach AGS 1.61328 0.689993 0.552401967825797 0.88537226062228 DataSet_03_108
GAB3 GATA6 siRNA Stomach YCC3 2.39241 1.25846 0.0330240292743775 0.5672562713455 DataSet_03_110
GAB3 MEF2D shRNA Liver HuH7 1.73464 0.794638 - - DataSet_03_162
GAB3 MYC siRNA Colon HT29 3.92779 1.97372 - - DataSet_03_177
GAB3 SOX11 siRNA Lung_fibroblast NHLF 2.03557 1.02544 0.0188596736384674 0.232617010694447 DataSet_03_238
GAB3 STAT6 siRNA Umbilical_vein HUVEC 0.391081 -1.35446 0.0215029149115352 0.601846221944029 DataSet_03_264
GAB3 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.566275 -0.820426 0.00108758474398102 0.0198620314540984 DataSet_04_004
GAB3 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.93529 0.952548 0.00304795779463316 0.0577726925005997 DataSet_04_010
GAB3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 1.70401 0.768932 0.155735690950406 0.286893137681463 DataSet_04_014
GAB3 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.603917 -0.727578 0.0282450580055945 0.140481999027825 DataSet_04_023
GAB3 CALR shRNA Liver HepG2 22 4.45943 0.222982900551004 0.350217104260008 DataSet_04_053
GAB3 NPM1 shRNA Liver HepG2 0.5 -1 0.950730627066374 0.995448784130025 DataSet_04_058
GAB3 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.78893 0.839095 0.000233673753001208 0.0151864618656269 DataSet_04_060
GAB3 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6022 0.680057 0.00584806986509054 0.0547374667077854 DataSet_04_064
GAB3 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 1.5632 0.644498 0.00190536141491355 0.0489306062498182 DataSet_04_061
GAB3 CNOT3 shRNA Lung A549 2.63531 1.39797 7.491138e-02 0.8830540 DataSet_03_340
GAB3 SMARCA4 siRNA Colon HCT116 0.473227 -1.07939 4.109967e-02 0.2040654 DataSet_03_302
GAB3 ELF3 CRISPR Bile_duct HBDEC2 2.26753 1.18112 7.350889e-04 4.887926e-03 DataSet_03_304
GAB3 INO80 siRNA Muscle RD 0.598514 -0.740544 - - DataSet_03_344
GAB3 BRCA1 siRNA Mammary_gland MCF7 0.562662 -0.82966 3.275221e-01 0.9999931 DataSet_03_308
GAB3 ESR1 siRNA Mammary_gland MCF7 3.80899 1.92941 7.143313e-02 0.2293059259 DataSet_03_352
GAB3 ETV5 knockdown Colon HT29 0.1875 -2.41504 7.044266e-02 0.292264353 DataSet_03_353
GAB3 PARP1 siRNA Prostate LNCaP 4.63183 2.21158 2.896584e-01 0.583280837 DataSet_03_354
GAB3 TET1 CRISPR Mammary_gland Hs578T 1.9868 0.990444 3.459417e-01 5.396976e-01 DataSet_03_355
GAB3 PTPN14 CRISPR Brain U5-NPC 0.326577 -1.61451 4.516636e-02 0.26917460 DataSet_03_357
GAB3 TP53 CRISPR Brain U5-NPC 1.91667 0.938599 5.100983e-01 6.327615e-01 DataSet_03_358
GAB3 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.51892 0.603049 1.911079e-03 6.977782e-02 DataSet_03_359
GAB3 EP300 shRNA Mammary_gland MCF10AT 9.14286 3.19265 6.444400e-02 0.213352479 DataSet_03_364
GAB3 TP53 knockout Stomach SNU1 2.18124 1.12515 0.0265692846 0.9301241 DataSet_03_365
GAB3 DNMT3A knockout Embryo_kidney HEK293T 0.185939 -2.4271 - - DataSet_03_369
GAB3 ZFP36L1 siRNA Urinary_bladder J82 1.6 0.678072 - - DataSet_03_371
GAB3 E2F1 siRNA Nasopharynx HK1 0.571429 -0.807355 5.724649e-01 1.000000e+00 DataSet_03_373
GAB3 HNRNPU siRNA Colon RKO 3.99448 1.99801 - - DataSet_03_374
GAB3 DDX5 shRNA Stomach HGC-27 1.93333 0.95109 - - DataSet_03_379
GAB3 DNMT1 siRNA Skin Human melanoma cells 1.87393 0.906067 1.723202e-03 4.924893e-03 DataSet_03_382
GAB3 TCF19 CRISPR Oral_squamous CAL27 0.335548 -1.57541 1.280735e-02 0.0880370414 DataSet_03_383
GAB3 YY1 shRNA Brain GSC1517 1.73103 0.791635 - - DataSet_03_384
GAB3 TRIM8 siRNA Mammary_gland MCF7 0.142857 -2.80735 4.809285e-01 0.6681945196 DataSet_03_388
GAB3 NFKBIA shRNA Bone_marrow U2OS 0.356442 -1.48826 1.598159e-01 0.87005461 DataSet_03_389
GAB3 JAZF1 siRNA Cervix HeLa Kyoto 0.627738 -0.671766 9.821838e-01 0.998912369 DataSet_03_396
GAB3 RELA CRISPR Brain T30 5.31623 2.4104 0.1058005679 0.8400824 DataSet_03_399
GAB3 EHF shRNA Stomach MKN7 0.0204702 -5.61033 - - DataSet_03_402
GAB3 TFAP2A knockout Embryo H9 0.5 -1 2.859536e-01 0.42275578 DataSet_03_405
GAB3 SATB2 CRISPR Colon Colon organoid 4 2 9.260593e-02 0.95735254 DataSet_03_406
GAB3 MAP3K7 shRNA Prostate LNCaP 2 1 1.105004e-02 8.635720e-02 DataSet_03_408
GAB3 E2F1 siRNA Prostate LNCaP 0.160714 -2.63743 1.847685e-02 0.3925258935 DataSet_03_413
GAB3 ZKSCAN3 CRISPR Colon HCT116 0.18932 -2.4011 3.555589e-04 0.041034404 DataSet_03_415
GAB3 MAEL CRISPR Liver Alexander cells 0.109756 -3.18763 - - DataSet_03_423
GAB3 FOXP3 CRISPR Peripheral_blood Naive Treg 0.515964 -0.954658 4.620528e-01 0.760965795 DataSet_03_427
GAB3 USP7 shRNA Skin xenograft cells 0.37338 -1.42128 0.26251477 0.4348960 DataSet_03_431
GAB3 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.543711 -0.879088 - - DataSet_03_432
GAB3 POU2AF1 CRISPR Lymph SUDHL4 3.86667 1.95109 4.049598e-04 0.009207732 DataSet_03_435
GAB3 EP300 knockout Pancreas HPAF-II orthotopic cells 0.581897 -0.781165 4.562919e-01 6.440332e-01 DataSet_03_436
GAB3 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.72222 0.784271 5.103201e-01 0.95189163 DataSet_03_439
GAB3 HMG20A siRNA Mammary_gland MDA-MB-231 0.315789 -1.66297 0.0453138988 0.2403690 DataSet_03_442
GAB3 PHF14 siRNA Mammary_gland MDA-MB-231 0.442105 -1.17754 0.0093654147 0.2772439 DataSet_03_443
GAB3 CAMTA1 knockout Embryo_kidney HEK293T 4.4 2.1375 3.503677e-03 0.08052058 DataSet_03_448
GAB3 RELB CRISPR Colon SW480 2.41379 1.2713 2.400256e-02 1.251921e-01 DataSet_03_449
GAB3 CBX2 siRNA Mammary_gland MDA-MB-231 0.532691 -0.90863 1.517449e-03 1.217055e-02 DataSet_03_450
GAB3 CBX2 siRNA Mammary_gland MCF7 0.481828 -1.05341 6.851247e-01 0.8099030257 DataSet_03_451
GAB3 ARID1A shRNA Bile_duct MMNK1 0.637273 -0.650016 8.157804e-02 0.299213224 DataSet_03_458
GAB3 PARP1 knockout Embryo_kidney HEK293a 1.66904 0.739018 1.715823e-03 7.313908e-03 DataSet_03_464
GAB3 SMARCA1 Cas13 Embryo_kidney HEK293T 0.25 -2 - - DataSet_03_466
GAB3 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 4.13636 2.04836 - - DataSet_03_467
GAB3 EZH2 siRNA Prostate LNCaP 0.375 -1.41504 4.595974e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate RBM14 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of GAB3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines