Gene Overview
Target Gene: GRIA2
NCBI Official Symbol: GRIA2
Entrez ID: 2891
Ensembl ID: ENSG00000120251
Gene Full Name: glutamate ionotropic receptor AMPA type subunit 2
Strand: +
Gene Locus: 4q32.1
External Links:

GRIA2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate GRIA2   
T(co)Fs that Repress GRIA2
The Intensity of the Gene Regulated by T(co)Fs:
GRIA2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
GRIA2 FOXA1 shRNA Prostate 22RV1 0.65706 -0.60591 - - DataSet_01_105
GRIA2 ID1 siRNA Lung A549 1.87127 0.90402 0.19332 0.43073 DataSet_01_117
GRIA2 ZIC2 siRNA Pancreas PANC1 0.16733 -2.57921 - - DataSet_01_121
GRIA2 FOXM1 siRNA Central_nervous_system U87 3.43978 1.78232 - - DataSet_01_122
GRIA2 POLR3A siRNA Mammary_gland MCF7 2.26496 1.17948 - - DataSet_01_139
GRIA2 SOX4 shRNA Parotid_gland ACC3 0.58979 -0.76172 0.46111 0.98786 DataSet_01_140
GRIA2 TP53 siRNA Lung SAECs 0.61875 -0.69257 0.0744 0.45163 DataSet_01_175
GRIA2 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.63571 -0.65355 0.00533 0.06338 DataSet_01_185
GRIA2 GATA2 siRNA Prostate LNCaP 0.61282 -0.70645 0.22196 0.34708 DataSet_01_193
GRIA2 CREB1 shRNA Parotid_gland H3118 MEC 1.86218 0.89699 0.66744 0.86971 DataSet_01_194
GRIA2 TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.44146 1.28775 - - DataSet_01_197
GRIA2 TP63 siRNA Head_and_neck SCC-1 0.19068 -2.39077 - - DataSet_01_199
GRIA2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 3.37417 1.75453 - - DataSet_01_208
GRIA2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 1.57809 0.65818 - - DataSet_01_209
GRIA2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.01127 1.59037 - - DataSet_01_210
GRIA2 ERG siRNA Prostate VCaP 0.66565 -0.58717 9e-04 0.01959 DataSet_01_216
GRIA2 TWIST1 shRNA Stomach CAF14 0.57356 -0.80199 0.01981 0.99996 DataSet_01_252
GRIA2 PTEN shRNA Lung A549 1.72052 0.78284 2.85779e-09 2.49173e-06 DataSet_01_276
GRIA2 MSX1 siRNA Tooth Dental Pulp Cells 0.44843 -1.15705 0.00243 0.0098 DataSet_01_281
GRIA2 ZIC5 siRNA Skin A375 0.54546 -0.87447 - - DataSet_01_284
GRIA2 POSTN shRNA Brain GSC272 2.60857 1.38326 0.06614 0.53976 DataSet_01_293
GRIA2 TFAP4 siRNA Brain BE(2)-C 0.12656 -2.98211 0.21907 0.51625 DataSet_01_295
GRIA2 SOX17 siRNA Umbilical_vein HUVEC 1.97567 0.98235 0.07533 0.99998 DataSet_01_300
GRIA2 PTEN shRNA Lung HCC827 0.62875 -0.66943 0.74556 0.92156 DataSet_01_302
GRIA2 SOX9 siRNA Prostate VCaP 0.64276 -0.63764 0.21698 0.9316 DataSet_01_308
GRIA2 SOX9 siRNA Prostate VCaP 0.64276 -0.63764 0.21698 0.9316 DataSet_01_309
GRIA2 HOXC6 siRNA Prostate LNCaP 0.57317 -0.80296 0.26313 0.99927 DataSet_01_333
GRIA2 KLF4 siRNA Embryo HCE 1.63472 0.70904 0.03481 0.36647 DataSet_01_339
GRIA2 GTF2B siRNA Cervix HeLa 0.55909 -0.83884 - - DataSet_01_362
GRIA2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 41 5.35755 0.4853 0.72401 DataSet_02_129
GRIA2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.48384 0.58826 DataSet_02_131
GRIA2 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 17 4.08746 0.01532 0.23648 DataSet_02_133
GRIA2 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 16 4 0.28231 0.51909 DataSet_02_137
GRIA2 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.10371 0.3769 DataSet_02_138
GRIA2 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.07737 0.22213 DataSet_02_142
GRIA2 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 4.75 2.24793 0.04448 0.30741 DataSet_02_152
GRIA2 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.00091 0.36048 DataSet_02_154
GRIA2 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.05556 -4.16993 0.01209 0.59238 DataSet_02_159
GRIA2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 16 4 0.01043 0.05465 DataSet_02_169
GRIA2 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.02215 0.08894 DataSet_02_170
GRIA2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21429 -2.22239 0.0298 0.22455 DataSet_02_171
GRIA2 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.04153 1 DataSet_02_173
GRIA2 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.03567 1 DataSet_02_175
GRIA2 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 9 3.16993 0.01464 1 DataSet_02_176
GRIA2 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 12 3.58496 0.01623 1 DataSet_02_177
GRIA2 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.35294 -1.5025 0.10106 1 DataSet_02_178
GRIA2 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.55882 -0.83954 0.2542 1 DataSet_02_180
GRIA2 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.0419 1 DataSet_02_183
GRIA2 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.02941 -5.08746 0.01641 1 DataSet_02_184
GRIA2 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.05882 -4.08746 0.01389 1 DataSet_02_187
GRIA2 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.06721 1 DataSet_02_189
GRIA2 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.04134 1 DataSet_02_192
GRIA2 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.04155 1 DataSet_02_194
GRIA2 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.06961 1 DataSet_02_195
GRIA2 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.07225 1 DataSet_02_197
GRIA2 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.04717 1 DataSet_02_200
GRIA2 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.09458 1 DataSet_02_202
GRIA2 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.05882 -4.08746 0.01705 1 DataSet_02_203
GRIA2 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 56 5.80735 0.02606 1 DataSet_02_205
GRIA2 ZFX siRNA Mammary_gland MCF7 5 2.32193 0.00052 0.02568 DataSet_02_206
GRIA2 AR siRNA Prostate LNCaP 2.22759 1.15548 0.106314358540792 1 DataSet_03_005
GRIA2 CEBPB siRNA Embryo hESC 3.35618 1.74682 0.113312300796406 0.48660227168024 DataSet_03_049
GRIA2 GATA2 siRNA Uterus Decidual stromal cells 1.78912 0.839248 0.0187506185850691 0.493371379659382 DataSet_03_100
GRIA2 GATA4 siRNA Stomach AGS 2.02253 1.01616 0.116393789362077 0.770202610597502 DataSet_03_105
GRIA2 HIC1 CRISPR Prostate PC3 1.96436 0.974061 - - DataSet_03_118
GRIA2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.197584 -2.33946 0.00401712371481618 0.480612232289195 DataSet_03_134
GRIA2 JARID1A siRNA Brain NB1691 1.89349 0.92105 0.000102598699322411 0.13625791261345 DataSet_03_136
GRIA2 MEF2D shRNA Liver HuH7 1.60877 0.685954 - - DataSet_03_162
GRIA2 MITF siRNA Skin Ma-Mel-15 0.598029 -0.741712 0.0342331085374494 0.360039297371125 DataSet_03_166
GRIA2 MITF siRNA Skin Ma-Mel-15 0.665239 -0.588055 0.00581563929802761 0.097875431679469 DataSet_03_167
GRIA2 MTA2 siRNA Stomach SGC-7901 0.489155 -1.03164 - - DataSet_03_169
GRIA2 MYB siRNA Cord_Blood CD34+ progenitor cells 1.70718 0.771615 - - DataSet_03_170
GRIA2 MYB siRNA Prostate VCaP 2.85733 1.51467 0.00010711044272958 0.0134660706390507 DataSet_03_174
GRIA2 MYC siRNA Colon HT29 0.213735 -2.2261 - - DataSet_03_177
GRIA2 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.47765 1.30897 0.21535664432209 0.349381789990625 DataSet_03_211
GRIA2 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.60919 0.686339 - - DataSet_03_246
GRIA2 STAT3 CRISPR Embryo hESC 7.36841 2.88135 0.0263380287434469 0.0930166427025557 DataSet_03_258
GRIA2 STAT6 siRNA Umbilical_vein HUVEC 1.60684 0.684224 0.646127368836179 0.95016888885733 DataSet_03_264
GRIA2 TFAP2C siRNA Mammary_gland MCF7 1.81091 0.856713 0.21783332139079 0.567100468921538 DataSet_03_274
GRIA2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.515152 -0.956931 0.111269576544885 0.216685477900449 DataSet_04_002
GRIA2 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.437853103540171 0.726667229807652 DataSet_04_008
GRIA2 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.0521844369041686 0.749733701968806 DataSet_04_013
GRIA2 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.181818 -2.45943 0.0833601862062754 0.614226806633224 DataSet_04_047
GRIA2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.858935043570345 0.927699685105058 DataSet_02_33
GRIA2 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.0915096485442594 0.239086256229801 DataSet_04_061
GRIA2 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.111111 -3.16992 0.421223231690036 0.759509309909076 DataSet_04_065
GRIA2 TET1 CRISPR Mammary_gland MDA-MB-231 17.6173 4.13892 5.624259e-01 7.326697e-01 DataSet_03_347
GRIA2 SKI CRISPR Blood HL60 2 1 5.636288e-01 0.784948295 DataSet_03_351
GRIA2 TET1 CRISPR Mammary_gland Hs578T 2.7022 1.43413 5.714436e-01 7.396395e-01 DataSet_03_355
GRIA2 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 2.33689 1.22459 1.688134e-01 2.577440e-01 DataSet_03_362
GRIA2 TPR shRNA Bone_marrow U2OS 2.16464 1.11413 1.548422e-01 5.672595e-01 DataSet_03_370
GRIA2 ZNF213 siRNA Mammary_gland MCF7 0.0933876 -3.42062 1.747043e-01 6.592819e-01 DataSet_03_376
GRIA2 TCF19 CRISPR Oral_squamous CAL27 0.479204 -1.06129 7.920647e-01 0.9144215737 DataSet_03_383
GRIA2 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.8004 0.848315 0.5929341622 0.9153627 DataSet_03_387
GRIA2 TRIM8 siRNA Mammary_gland MCF7 0.5 -1 8.933182e-01 0.9442935773 DataSet_03_388
GRIA2 NFKBIA shRNA Bone_marrow U2OS 0.00797696 -6.96995 4.566769e-01 0.87005461 DataSet_03_389
GRIA2 KDM5A CRISPR Lung GLC16 1.66982 0.739693 3.885721e-04 0.012331916 DataSet_03_392
GRIA2 ILF2 siRNA Stomach SGC-7901 0.166667 -2.58496 0.0732092522 0.20612629 DataSet_03_393
GRIA2 RELA CRISPR Brain T30 0.122818 -3.02541 0.4316348171 0.8400824 DataSet_03_399
GRIA2 HMGA1 shRNA Bile_duct HUCCT1 3.5 1.80736 5.699058e-02 0.286445934 DataSet_03_400
GRIA2 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 0.5 -1 7.234350e-01 0.8138401 DataSet_03_403
GRIA2 CDK7 shRNA Bone_marrow D458 0.333333 -1.58496 3.356187e-01 0.62549455 DataSet_03_404
GRIA2 STRAP knockout Nerve SK-N-AS 0.212519 -2.23434 - - DataSet_03_409
GRIA2 E2F6 shRNA Liver HuH7 0.258673 -1.9508 - - DataSet_03_412
GRIA2 FOXK2 shRNA Ovary OVCAR-5 2 1 7.262797e-01 0.80926985 DataSet_03_419
GRIA2 STAT5B CRISPR Embryo_kidney HEK293 0.5 -1 1.665151e-01 0.665084591 DataSet_03_424
GRIA2 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.5 -1 9.592861e-03 7.468802e-01 DataSet_03_428
GRIA2 USP7 shRNA Skin xenograft cells 0.545455 -0.874469 0.31024813 0.4527633 DataSet_03_431
GRIA2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 6.375 2.67243 1.141738e-02 0.53026756 DataSet_03_439
GRIA2 FOSL1 siRNA Prostate MSKPCa3 0.461538 -1.11548 0.1798523042 0.5297688 DataSet_03_445
GRIA2 CBX2 siRNA Mammary_gland MCF7 9.32443 3.22101 8.899717e-03 0.0277513813 DataSet_03_451
GRIA2 ZFP36L1 CRISPR Lung NCI-H1876 0.643488 -0.636014 9.456939e-01 0.997977363 DataSet_03_454
GRIA2 SREBF2 siRNA Umbilical_vein HUVEC 3.26778 1.70831 5.704850e-01 8.728338e-01 DataSet_03_457
GRIA2 ARID1A shRNA Bile_duct MMNK1 0.628139 -0.670843 7.484097e-01 0.878270395 DataSet_03_458
GRIA2 HAND1 siRNA Placenta HPMVEC 0.09375 -3.41504 3.013564e-01 0.9463341 DataSet_03_459
GRIA2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 6 2.58496 - - DataSet_03_467
GRIA2 SMARCA1 shRNA Embryo_kidney HEK293T 0.5 -1 - - DataSet_03_468
GRIA2 LIN28A siRNA Mammary_gland MCF7M 1.61507 0.691595 9.330025e-01 0.9997505 DataSet_03_469
GRIA2 LIN28A siRNA Mammary_gland MCF7M 1.61507 0.691595 9.330025e-01 0.9997505 DataSet_03_470
GRIA2 EZH2 siRNA Umbilical_vein HUVEC 0.578947 -0.788496 7.886443e-02 0.297985550 DataSet_03_473
GRIA2 EZH2 siRNA Prostate LNCaP 2 1 8.952597e-01 1.0000000 DataSet_03_475
GRIA2 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0606061 -4.04439 0.06044955 0.8431706 DataSet_04_071
GRIA2 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.5018405 0.8615781 DataSet_04_072
GRIA2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.515152 -0.956931 0.2475728 0.401362457 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate POLR2G by the evidences of both expression and ChIP-seq/motif
Expression Atlas of GRIA2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines