Gene Overview
Target Gene: Gzma
NCBI Official Symbol: Gzma
Entrez ID: 14938
Ensembl ID: ENSMUSG00000023132
Gene Full Name: granzyme A
Strand: -
Gene Locus: 13 D2.2|13 63.93 cM
External Links:

Gzma Significantly Regulated by These T(co)Fs

T(co)Fs that Activate Gzma   
T(co)Fs that Repress Gzma
The Intensity of the Gene Regulated by T(co)Fs:
Gzma-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
Gzma Ahr knockout Lung Lung 1.72761 0.788778 0.930340865629825 0.999996968611848 DataSet_11_003
Gzma Atf3 knockout Mammary_gland Breast tumor-associated macrophage 2.07926 1.05607 0.15017392649299 1 DataSet_11_006
Gzma Atoh1 knockout Gastrointestinal_tissue Intestinal epithelial Lgr5(hi) stem cells 32.7711 5.03435 0.000591311908744523 0.00477464507861406 DataSet_11_010
Gzma Bhlha9 knockout Limb Whole limb bud 4.55713 2.18812 - - DataSet_11_016
Gzma Cbfb knockdown Peripheral_blood Peripheral CD4+CD25hi cells 2.35653 1.23667 0.0366073163874196 0.735729020534371 DataSet_11_017
Gzma Cebpb shRNA Mammary_gland 4T1 mammary tumor cells 2.22289 1.15243 0.235073587623038 0.999984070881864 DataSet_11_022
Gzma Dmrt1 knockout Testis Juvenile testes 1.5752 0.655534 0.029884195509532 0.475178000522961 DataSet_11_025
Gzma Dmrt1 knockout Testis Juvenile testes 1.61117 0.68811 0.107335926803427 0.932139260123802 DataSet_11_026
Gzma Dmrt1 knockout Testis Juvenile testes 1.52925 0.612821 0.00605371835054275 0.503050904316327 DataSet_11_028
Gzma Dmrt1 knockout Testis Testes 0.120476 -3.05318 4.8366064823899e-05 0.00627315215512822 DataSet_11_029
Gzma Dmrt1 knockout Testis Testes 0.120476 -3.05318 4.8366064823899e-05 0.00627315215512822 DataSet_11_032
Gzma E2f4 knockout Brain Forebrain 0.338223 -1.56395 - - DataSet_11_033
Gzma Elf5 knockout Mammary_gland Mammary gland 0.623462 -0.681626 0.515420772712023 0.739518819508254 DataSet_11_035
Gzma Foxa2 knockout Lung Whole lung 3.37578 1.75522 0.318732537767521 0.716127037579273 DataSet_11_041
Gzma Gata2 knockout Kidney renal collecting duct cells 2.07929 1.0561 - - DataSet_11_047
Gzma Gfi1 knockout Cord_Blood T-cells 0.521139 -0.940259 0.149479887680866 0.557097905674787 DataSet_11_053
Gzma Hsf4 knockout Eye Lens 1.6559 0.727613 0.603518522190784 0.987999303842427 DataSet_11_058
Gzma Junb shRNA Tibialis_anterior_muscle Tibialis anterior muscle 0.35296 -1.50242 0.0228426776662547 0.153812583051552 DataSet_11_065
Gzma Lhx8 knockout Ovary Ovary 2.11814 1.0828 0.27186478549809 0.434183992917216 DataSet_11_070
Gzma Lmx1b knockout Kidney Kidney 0.387444 -1.36794 0.00384904755473116 0.119103611259292 DataSet_11_072
Gzma Mafg knockout Embryo Whole embryo 0.0213081 -5.55246 9.65928712814561e-07 0.000632478412924153 DataSet_11_073
Gzma Mbd2 knockout Lymph GFP+ BM leukemia cells 4.50292 2.17086 1.68044394699218e-05 0.000471638537274219 DataSet_11_076
Gzma Meis1 knockout Hematopoietic KSL hematopoietic cells 0.365171 -1.45335 0.0392372884675816 0.995635220774426 DataSet_11_081
Gzma Neurod1 knockout Eye Pineal gland 0.638356 -0.647566 0.0702755818657731 0.424636995788926 DataSet_11_087
Gzma Neurod1 knockout Eye Retina 2.061 1.04334 0.0243544035259506 0.103773785798979 DataSet_11_088
Gzma Neurod1 knockout Eye Pineal gland 2.93384 1.55279 0.0168935367084105 0.9983937273602 DataSet_11_089
Gzma Nfil3 knockout Bone_marrow Prepro NK cells 1.5955 0.674005 0.333758013025626 0.616180098855827 DataSet_11_090
Gzma Nrf1 knockdown Liver Liver 1.57585 0.656126 0.161404390173203 0.278186652537494 DataSet_11_096
Gzma Otx2 knockout Eye Retina 0.391753 -1.35198 0.102121681130388 0.999923528647439 DataSet_11_097
Gzma Pitx2 knockout Eye Cornea 0.412615 -1.27713 0.00824845372125468 0.142101409890805 DataSet_11_103
Gzma Plagl2 knockout Intestine Small intestine 0.444685 -1.16914 0.0482752377373608 0.262226337201447 DataSet_11_104
Gzma Pparg siRNA Adipose_tissue Preadipocytes 2.03358 1.02402 0.0829766727393813 0.647923693269021 DataSet_11_105
Gzma Prox1 knockout Liver Liver 0.62192 -0.685199 - - DataSet_11_109
Gzma Runx1 knockout Bone_marrow KSL cells 0.378724 -1.40078 0.00397849280154743 0.326111299890363 DataSet_11_115
Gzma Runx1 knockout Mammary_gland Luminal epithelial cells 0.421095 -1.24778 0.44366867977259 0.999784944667092 DataSet_11_117
Gzma Runx2 knockout Humeri Embryonic humeri 1.52049 0.604538 0.43902250246659 0.725511794138141 DataSet_11_120
Gzma Smad4 siRNA Brain bEnd3 1.69542 0.76164 - - DataSet_11_127
Gzma Smad4 knockout Aorta Aortic arteries 4.2707 2.09447 0.0118424546309737 0.170084733193829 DataSet_11_128
Gzma Sp3 knockout Heart Heart 0.243619 -2.0373 0.000157146867840072 0.183404580428253 DataSet_11_145
Gzma Spdef knockout Colon Colon 0.342992 -1.54375 0.294983053664508 0.997507742354799 DataSet_11_146
Gzma Spdef knockout Stomach Stomach 1.93623 0.953246 0.0925950741021442 0.856290627784147 DataSet_11_147
Gzma Stat3 knockout Lung Lung typeII cells 1.95483 0.967043 0.0678932769452367 0.69769295524883 DataSet_11_151
Gzma Stat4 knockout Lymph Lamina propria lymphocytes 0.215109 -2.21686 0.0108895991002787 0.71816236724679 DataSet_11_152
Gzma Stat6 knockout Bone_marrow Bone marrow-derived macrophages 0.234957 -2.08953 0.0300422815612346 0.102134591108195 DataSet_11_153
Gzma Tbx1 knockout Ear Otic vesicles 7.50363 2.90759 0.0951822259818855 0.739300722608655 DataSet_11_155
Gzma Tsc22d4 shRNA Liver Liver 0.089674 -3.47917 6.2484626280249e-06 0.000366110902452235 DataSet_11_169
Gzma Cpeb1 siRNA Neuron Neuro-2a 6.03086 2.59236 - - DataSet_11_189
Gzma Kdm5b knockout Heart left ventricles 0.291145 -1.78019 0.1804564284 0.9999827 DataSet_11_210
Gzma Smarca4 shRNA Embryo ES cells 1.80914 0.855303 - - DataSet_11_224
Gzma Smarca4 shRNA Embryo ES cells 1.80914 0.855303 - - DataSet_11_225
Gzma Crebbp knockout Spleen Germinal center B cells 0.194104 -2.36509 9.541635e-02 0.714422219 DataSet_11_227
Gzma Twist1 knockout Bone_marrow stromal cells 7.91732 2.98501 - - DataSet_11_244
Gzma Mecp2 knockout Adipose_tissue inguinal adipose tissue 1.88984 0.918267 1.442253e-02 0.1490822 DataSet_11_254
Gzma Eed knockout Brain Forebrain 0.616613 -0.697562 4.464285e-01 7.656443e-01 DataSet_11_258
Gzma Eed knockout Brain hindbrain 2.76872 1.46922 1.878921e-01 9.999914e-01 DataSet_11_259
Gzma Eed knockout Brain midbrain 0.62953 -0.667654 7.103669e-01 9.988327e-01 DataSet_11_260
Gzma Eed knockout Spinal_cord spinal cord 0.555765 -0.847452 5.682785e-01 9.999790e-01 DataSet_11_261
Gzma Fubp1 shRNA Bone_marrow BM cells 3.14286 1.65208 3.195559e-01 0.846117121 DataSet_11_262
Gzma Bcl3 knockout Bone Osteoblast 0.476923 -1.06817 3.021622e-02 6.225870e-01 DataSet_11_263
Gzma Mef2d CRISPR Heart Cardiac ventricle 1.7305 0.791192 3.693933e-01 0.6073656213 DataSet_11_270
Gzma Ssrp1 CRISPR Embryo ES cells 0.5 -1 7.472217e-01 0.9363812 DataSet_11_278
Gzma Usp7 knockout Embryo ES cells 0.5 -1 7.199797e-01 0.8766991 DataSet_11_279
Gzma Pcgf6 knockout Brain Brain 0.204148 -2.29232 2.130011e-01 0.988876895 DataSet_11_280
Gzma Pcgf6 knockout Liver Liver 2.40586 1.26655 2.777240e-03 0.6749546 DataSet_11_281
Gzma Pdx1 CRISPR Liver Liver 0.288809 -1.79181 4.609950e-03 0.289297274 DataSet_11_286
Gzma Fli1 CRISPR Lymph CD8 T cells 1.64651 0.71941 4.358834e-01 0.9999740103 DataSet_11_288
Gzma Sirt3 knockout Pancreatic_islets pancreatic beta cell 7.93478 2.98819 1.246093e-01 6.506352e-01 DataSet_11_297
Gzma Phf8 knockout prostate Prostate 0.0254237 -5.29768 0.0080366382 0.1692446 DataSet_11_298
Gzma Arid2 knockout Muscle LSK 0.324561 -1.62344 3.397906e-02 6.219320e-01 DataSet_11_301
Gzma Jmjd6 knockout Bone_marrow Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells 2.33333 1.22239 - - DataSet_11_306
Gzma Esr1 knockout Liver Liver 0.641304 -0.640919 2.222119e-01 1.0000000 DataSet_11_307
Gzma Cited2 knockout Haematopoietic_and_lymphoid_tissue Hematopoietic stem cell (HSC) 2.25 1.16992 - - DataSet_11_308
Gzma Suz12 knockout Lung Alveolar macrophage 4.4127 2.14166 2.378699e-01 0.6512347951 DataSet_11_311
Gzma Suz12 knockout Lung Alveolar macrophage 0.471233 -1.08549 7.797759e-01 8.070754e-01 DataSet_11_312
Gzma Irf7 knockout Bone_marrow c-kit+ leukemic cells 6.78788 2.76296 - - DataSet_11_313
Gzma Actl6a knockout Nerve sciatic nerve 13.3333 3.73697 4.602710e-03 0.097933310 DataSet_11_314
Gzma Satb2 knockout Colon Intestine epithelium 0.280493 -1.83397 4.378268e-02 0.3306981408 DataSet_11_316
Gzma Arid1b knockout Bone_marrow bone marrow leukemia cells 0.209302 -2.25634 3.585194e-02 0.2481806652 DataSet_11_317
Gzma Arid2 knockout Bone_marrow bone marrow leukemia cells 2.43902 1.2863 2.713091e-01 0.7527440 DataSet_11_318
Gzma Bud31 knockout Testis Spermatogonial stem cells 15.1897 3.92502 2.148473e-02 0.8600602 DataSet_11_321
Gzma Snai1 knockdown Heart Heart 0.456392 -1.13165 3.505647e-01 0.55865342 DataSet_11_326
Gzma Gtf2ird1 knockout Lip Lip 1.66667 0.736966 2.520030e-01 6.943149e-01 DataSet_11_339
Gzma Ezh2 knockout Small_intestinal_crypts small intestinal crypts 0.133698 -2.90295 0.1092370682 0.1833929 DataSet_11_341
Gzma Dnmt1 knockout Kidney kidney Cap Mesenchyme 2.26621 1.18028 4.807509e-01 7.140150e-01 DataSet_11_344
Regulation Region
 
T(co)Fs that significantly regulate Crebbp by the evidences of both expression and ChIP-seq/motif
Expression Atlas of Gzma
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)