Gene Overview
| Target Gene: | Lgals2 |
| NCBI Official Symbol: | Lgals2 |
| Entrez ID: | 107753 |
| Ensembl ID: | ENSMUSG00000043501 |
| Gene Full Name: | lectin, galactose-binding, soluble 2 |
| Strand: | - |
| Gene Locus: | 15|15 E1 |
| External Links: |
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Lgals2 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Lgals2
T(co)Fs
that Repress Lgals2
The Intensity of the Gene Regulated by T(co)Fs:
Lgals2-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Lgals2 | Adnp | knockout | Embryo | Whole embryonic body | 5.06066 | 2.33932 | 0.0120434756526911 | 0.307769839571615 | DataSet_11_001 |
| Lgals2 | Atf3 | knockout | Mammary_gland | Breast tumor-associated macrophage | 1.6171 | 0.693409 | 0.178654749184202 | 1 | DataSet_11_006 |
| Lgals2 | Dmrt1 | knockout | Testis | Testes | 0.382357 | -1.38701 | 0.00145547043989553 | 0.0476150037758252 | DataSet_11_029 |
| Lgals2 | Dmrt1 | knockout | Ovary | Ovary | 2.06254 | 1.04442 | 0.00306599236993922 | 0.063464818108692 | DataSet_11_030 |
| Lgals2 | Dmrt1 | knockout | Ovary | Ovary | 2.06254 | 1.04442 | 0.00306599236993922 | 0.063464818108692 | DataSet_11_031 |
| Lgals2 | Dmrt1 | knockout | Testis | Testes | 0.382357 | -1.38701 | 0.00145547043989553 | 0.0476150037758252 | DataSet_11_032 |
| Lgals2 | Foxq1 | siRNA | Mammary_gland | NM18 | 3.19262 | 1.67474 | 0.000787413621154443 | 0.00846031469456377 | DataSet_11_045 |
| Lgals2 | Gata2 | knockout | Kidney | renal collecting duct cells | 1.68445 | 0.752273 | - | - | DataSet_11_047 |
| Lgals2 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 1.78573 | 0.836515 | 0.0716644178224155 | 0.987135756219234 | DataSet_11_048 |
| Lgals2 | Hsf4 | knockout | Eye | Lens | 0.638751 | -0.646675 | 0.709368560221419 | 0.987999303842427 | DataSet_11_058 |
| Lgals2 | Irf6 | knockout | Skin | Skin | 2.4376 | 1.28546 | 0.0336961369084596 | 0.237880046160095 | DataSet_11_062 |
| Lgals2 | Mafg | knockout | Embryo | Whole embryo | 0.473812 | -1.07761 | 0.218672266689008 | 1 | DataSet_11_073 |
| Lgals2 | Neurod1 | knockout | Eye | Retina | 1.75048 | 0.807751 | 0.0223355673134298 | 0.0987976117824369 | DataSet_11_088 |
| Lgals2 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 5.01188 | 2.32535 | 0.00325468201345251 | 0.101218381384117 | DataSet_11_105 |
| Lgals2 | Prox1 | knockout | Liver | Liver | 0.561639 | -0.832285 | - | - | DataSet_11_109 |
| Lgals2 | Runx1 | knockout | Lymph | ProB cells | 1.59284 | 0.671603 | 0.589443495072936 | 0.837905713896375 | DataSet_11_116 |
| Lgals2 | Snai1 | knockout | Embryo | Embryoid body | 0.0527127 | -4.24571 | - | - | DataSet_11_129 |
| Lgals2 | Snai1 | knockout | Embryo | Teratoma | 0.600116 | -0.736687 | - | - | DataSet_11_130 |
| Lgals2 | Sox11 | knockout | Eye | Retina | 2.41892 | 1.27436 | - | - | DataSet_11_137 |
| Lgals2 | Sox2 | shRNA | Embryo | ES cells | 2.29939 | 1.20125 | - | - | DataSet_11_140 |
| Lgals2 | Sp3 | knockout | Heart | Heart | 0.617838 | -0.694699 | 0.0320812987534311 | 0.675730387360493 | DataSet_11_145 |
| Lgals2 | Spdef | knockout | Colon | Colon | 0.00869758 | -6.84517 | 0.202511618886559 | 0.997507742354799 | DataSet_11_146 |
| Lgals2 | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.596748 | -0.744807 | 0.00317502613854142 | 0.0363003450579809 | DataSet_11_179 |
| Lgals2 | Pogz | knockdown | Liver | fetal liver | 0.648248 | -0.625382 | 1.881130e-01 | 0.4889481 | DataSet_11_188 |
| Lgals2 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.487361 | -1.03694 | - | - | DataSet_11_189 |
| Lgals2 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 5.15058 | 2.36473 | 8.192485e-04 | 1.257595e-02 | DataSet_11_192 |
| Lgals2 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 2.42963 | 1.28074 | - | - | DataSet_11_196 |
| Lgals2 | Ezh2 | knockdown | Brain | Brain | 0.631168 | -0.663904 | 2.884913e-01 | 0.6438819014 | DataSet_11_221 |
| Lgals2 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 3 | 1.58496 | 5.190516e-01 | 1.0000000 | DataSet_11_208 |
| Lgals2 | Twist1 | knockout | Bone_marrow | stromal cells | 2.74928e-19 | -61.6576 | - | - | DataSet_11_244 |
| Lgals2 | Fubp1 | shRNA | Brain | brain neural progenitors | 1.90896 | 0.932788 | 0.4569553474 | 1 | DataSet_11_246 |
| Lgals2 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.5 | -1 | 5.081844e-01 | 6.391601e-01 | DataSet_11_250 |
| Lgals2 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.142561 | -2.81035 | 1.981377e-04 | 0.015735192 | DataSet_11_252 |
| Lgals2 | Eed | knockout | Brain | hindbrain | 2.0175 | 1.01257 | 3.650465e-01 | 9.999914e-01 | DataSet_11_259 |
| Lgals2 | Eed | knockout | Spinal_cord | spinal cord | 0.504314 | -0.987606 | 2.375882e-03 | 5.212726e-01 | DataSet_11_261 |
| Lgals2 | Arhgap35 | knockout | Ventral_spinal_cord | Ventral spinal cord | 0.5 | -1 | 5.340995e-01 | 1.000000000 | DataSet_11_264 |
| Lgals2 | Dux | knockout | Embryo | Embryo | 0.252291 | -1.98684 | 2.381121e-01 | 4.197213e-01 | DataSet_11_269 |
| Lgals2 | Mef2d | CRISPR | Heart | Cardiac ventricle | 2.27063 | 1.18309 | 3.215796e-01 | 0.5690762631 | DataSet_11_270 |
| Lgals2 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 1430.49 | 10.4823 | 3.324637e-01 | 0.81420760 | DataSet_11_272 |
| Lgals2 | Dux | knockout | Embryo | Embryo | 0.252291 | -1.98684 | 2.381119e-01 | 4.197523e-01 | DataSet_11_273 |
| Lgals2 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.357223 | -1.48511 | 3.291268e-03 | 1.317700e-02 | DataSet_11_275 |
| Lgals2 | Ssrp1 | CRISPR | Embryo | ES cells | 3 | 1.58496 | 2.408941e-01 | 0.7914316 | DataSet_11_278 |
| Lgals2 | Pcgf6 | knockout | Brain | Brain | 0.646378 | -0.629551 | 2.097675e-01 | 0.988876895 | DataSet_11_280 |
| Lgals2 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 3.24264 | 1.69717 | 1.421071e-01 | 0.5395938 | DataSet_11_284 |
| Lgals2 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.52308 | 0.606989 | - | - | DataSet_11_285 |
| Lgals2 | Pdx1 | CRISPR | Liver | Liver | 0.404255 | -1.30666 | 1.130453e-01 | 0.415845061 | DataSet_11_286 |
| Lgals2 | Usp7 | siRNA | Embryo | ES cells | 1.58333 | 0.662965 | 8.480249e-01 | 0.9169560 | DataSet_11_287 |
| Lgals2 | Kmt2d | CRISPR | Liver | MA1L | 0.41282 | -1.27641 | 1.886368e-04 | 5.041140e-03 | DataSet_11_290 |
| Lgals2 | Kmt2d | CRISPR | Liver | MA1L | 0.422084 | -1.2444 | 2.397793e-04 | 6.332975e-03 | DataSet_11_291 |
| Lgals2 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 2.5 | 1.32193 | 8.187775e-01 | 0.9327240479 | DataSet_11_294 |
| Lgals2 | Tfap2a | knockout | Brain | Brain | 0.466667 | -1.09954 | 0.3470870135 | 0.9603575 | DataSet_11_295 |
| Lgals2 | Ssrp1 | CRISPR | Embryo | ES cells | 2.5 | 1.32193 | 5.015884e-01 | 0.69012252 | DataSet_11_296 |
| Lgals2 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 0.589412 | -0.762652 | 9.472540e-01 | 1.000000e+00 | DataSet_11_297 |
| Lgals2 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.565272 | -0.822983 | 4.199740e-01 | 0.9999903 | DataSet_11_299 |
| Lgals2 | Dnmt1 | knockout | Skin | Keratinocytes | 2.20934 | 1.14362 | 6.931588e-01 | 0.8726111309 | DataSet_11_303 |
| Lgals2 | Satb2 | CRISPR | Colon | Colon organoid | 2.34507 | 1.22963 | 2.002151e-02 | 0.6315226 | DataSet_11_304 |
| Lgals2 | Esr1 | knockout | Liver | Liver | 2.66667 | 1.41504 | 2.997928e-02 | 1.0000000 | DataSet_11_307 |
| Lgals2 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.10171 | -3.29747 | 5.663083e-01 | 0.88663527 | DataSet_11_310 |
| Lgals2 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 3.93043 | 1.97469 | - | - | DataSet_11_313 |
| Lgals2 | Actl6a | knockout | Nerve | sciatic nerve | 0.529412 | -0.917538 | 5.359469e-02 | 0.312895581 | DataSet_11_314 |
| Lgals2 | Ahr | knockout | Liver | Liver | 0.35 | -1.51457 | 1.231937e-01 | 0.5223613193 | DataSet_11_315 |
| Lgals2 | Satb2 | knockout | Colon | Intestine epithelium | 44.1526 | 5.46443 | 3.016013e-08 | 0.0001918809 | DataSet_11_316 |
| Lgals2 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.176471 | -2.5025 | 2.265052e-01 | 0.6232349145 | DataSet_11_317 |
| Lgals2 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.208333 | -2.26303 | 5.684469e-02 | 3.873359e-01 | DataSet_11_319 |
| Lgals2 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.20964 | -2.25401 | 3.667466e-03 | 5.399649e-02 | DataSet_11_320 |
| Lgals2 | Bud31 | knockout | Testis | Spermatogonial stem cells | 1.8 | 0.847997 | 7.640974e-01 | 0.9323612 | DataSet_11_321 |
| Lgals2 | Padi2 | knockout | Testis | Testis | 0.166667 | -2.58496 | 5.188854e-02 | 0.9481885 | DataSet_11_324 |
| Lgals2 | Dnmt1 | knockout | Brain | Cortex | 0.241288 | -2.05117 | 1.010457e-01 | 0.4752256699 | DataSet_11_329 |
| Lgals2 | Dnmt3a | knockout | Brain | Cortex | 0.385103 | -1.37668 | 1.963656e-01 | 0.8033910 | DataSet_11_330 |
| Lgals2 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.415264 | -1.2679 | 6.508946e-02 | 2.740377e-01 | DataSet_11_332 |
| Lgals2 | Ezh2 | knockout | Eye | Retina | 2.92634 | 1.5491 | 0.6657643809 | 1.0000000 | DataSet_11_334 |
| Lgals2 | Atrx | knockout | Embryo | ES cells | 2 | 1 | - | - | DataSet_11_335 |
| Lgals2 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 0.542583 | -0.882084 | - | - | DataSet_11_336 |
| Lgals2 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 1.54386 | 0.626542 | 6.665814e-02 | 0.55135465 | DataSet_11_338 |
| Lgals2 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 3.05799 | 1.61258 | 0.0628094609 | 0.1712697 | DataSet_11_341 |
| Lgals2 | Hnrnpk | siRNA | Embryo | ES cells | 0.455433 | -1.13469 | 6.143191e-02 | 0.108470071 | DataSet_11_342 |
| Lgals2 | Tbx20 | CRISPR | Heart | primary cardiac fibroblasts | 4 | 2 | 2.585372e-01 | 1.00000000 | DataSet_11_348 |
Regulation Region
Expression Atlas of Lgals2