Gene Overview
Target Gene: MMRN1
NCBI Official Symbol: MMRN1
Entrez ID: 22915
Ensembl ID: ENSG00000138722
Gene Full Name: multimerin 1
Strand: +
Gene Locus: 4q22.1
External Links:

MMRN1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate MMRN1   
T(co)Fs that Repress MMRN1
The Intensity of the Gene Regulated by T(co)Fs:
MMRN1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
MMRN1 ID1 siRNA Lung A549 2.88486 1.5285 0.02002 0.17314 DataSet_01_117
MMRN1 ID1 siRNA Lung H1650 0.52728 -0.92335 0.62952 0.84664 DataSet_01_118
MMRN1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.29928 1.20118 0.36734 0.99993 DataSet_01_137
MMRN1 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.44284 -1.17516 0.11655 0.39672 DataSet_01_154
MMRN1 GATA3 siRNA Peripheral_blood CD4+ T cells 0.44939 -1.15397 0.01682 0.22357 DataSet_01_163
MMRN1 TP53 siRNA Lung SAECs 0.37662 -1.40881 0.38947 0.75405 DataSet_01_175
MMRN1 GATA2 siRNA Prostate LNCaP 0.61967 -0.69043 0.10451 0.20202 DataSet_01_193
MMRN1 CREB1 shRNA Parotid_gland H3118 MEC 0.25888 -1.94963 0.61181 0.84685 DataSet_01_194
MMRN1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 3.83962 1.94096 - - DataSet_01_196
MMRN1 TP63 siRNA Immortalized_keratinocyte HaCaT 3.15306 1.65675 - - DataSet_01_200
MMRN1 TP63 siRNA Head_and_neck SCC-6 2.54608 1.34827 - - DataSet_01_202
MMRN1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.60396 -0.72747 - - DataSet_01_208
MMRN1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.25661 -1.96236 - - DataSet_01_209
MMRN1 REST siRNA Prostate LNCaP 0.60782 -0.71829 0.00266 0.11841 DataSet_01_211
MMRN1 LIN28A siRNA Embryo H9 0.28656 -1.80308 9.54618e-05 0.00294 DataSet_01_215
MMRN1 SNAI2 shRNA Skin Primary human keratinocytes 3.83529 1.93933 0.20928 0.3453 DataSet_01_225
MMRN1 TWIST1 shRNA Stomach CAF14 0.41742 -1.26043 0.28724 0.99996 DataSet_01_252
MMRN1 OTX2 siRNA Brain Neural precursor cells 1.61757 0.69382 0.00497 0.33435 DataSet_01_268
MMRN1 SALL4 shRNA Lung H661 1.52341 0.6073 0.02844 0.20626 DataSet_01_277
MMRN1 STAT5 shRNA Prostate CWR22Pc 1.96895 0.97743 0.14276 0.30022 DataSet_01_279
MMRN1 ESRRA shRNA Embryo_kidney 293T 2.13137 1.09178 0.27169 0.79425 DataSet_01_280
MMRN1 POSTN shRNA Brain GSC272 6.33248 2.66277 0.00943 0.47952 DataSet_01_293
MMRN1 TFAP4 siRNA Brain BE(2)-C 0.38633 -1.37211 0.52994 0.55158 DataSet_01_295
MMRN1 PTEN shRNA Skin A431 0.17307 -2.5306 0.02131 0.12577 DataSet_01_301
MMRN1 PTEN shRNA Mammary_gland SKBR3 1.82057 0.86439 0.58507 0.85684 DataSet_01_303
MMRN1 SOX9 siRNA Prostate VCaP 0.5 -1 0.93235 0.99611 DataSet_01_308
MMRN1 SOX9 siRNA Prostate VCaP 0.5 -1 0.93235 0.99611 DataSet_01_309
MMRN1 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.52955 -0.91717 0.08337 0.34353 DataSet_01_313
MMRN1 MYC siRNA Colon HCT116 1.8748 0.90674 0.10405 0.1508 DataSet_01_324
MMRN1 HOXC6 siRNA Prostate LNCaP 0.36496 -1.45418 0.3688 0.99927 DataSet_01_333
MMRN1 KLF4 siRNA Embryo HCE 0.5249 -0.92988 0.05535 0.50064 DataSet_01_341
MMRN1 TAF15 shRNA Liver HepG2 4 2 0.48044 0.55386 DataSet_02_106
MMRN1 ZNF622 shRNA Liver HepG2 3 1.58496 0.49994 0.5727 DataSet_02_108
MMRN1 BCLAF1 shRNA Liver HepG2 11 3.45943 0.45618 0.57281 DataSet_02_112
MMRN1 RBM25 shRNA Liver HepG2 2 1 1 1 DataSet_02_119
MMRN1 PTBP1 shRNA Liver HepG2 2 1 0.05658 0.08476 DataSet_02_120
MMRN1 RBM34 shRNA Liver HepG2 4 2 0.03183 0.40242 DataSet_02_121
MMRN1 FUS shRNA Liver HepG2 4 2 0.03069 0.13888 DataSet_02_124
MMRN1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.48066 0.58778 DataSet_02_131
MMRN1 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 9 3.16993 0.02144 0.11379 DataSet_02_134
MMRN1 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.08199 0.20881 DataSet_02_135
MMRN1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.08058 0.26565 DataSet_02_136
MMRN1 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.00665 0.19546 DataSet_02_137
MMRN1 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.00181 0.20864 DataSet_02_141
MMRN1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.02698 0.21383 DataSet_02_144
MMRN1 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.07976 0.19448 DataSet_02_147
MMRN1 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.11445 0.31158 DataSet_02_151
MMRN1 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.18182 -2.45943 0.75694 0.88797 DataSet_02_154
MMRN1 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.82275 0.93062 DataSet_02_156
MMRN1 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.18182 -2.45943 0.74214 0.99965 DataSet_02_157
MMRN1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.36364 -1.45943 0.63735 0.91255 DataSet_02_159
MMRN1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 1 1 DataSet_02_160
MMRN1 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.18182 -2.45943 0.75488 0.96331 DataSet_02_161
MMRN1 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.03437 0.11534 DataSet_02_168
MMRN1 ZFX siRNA Mammary_gland MCF7 1.8 0.848 0.44882 0.67382 DataSet_02_206
MMRN1 AR siRNA Prostate LNCaP 0.28 -1.8365 0.0338131906169573 1 DataSet_03_005
MMRN1 ASCL1 siRNA Lung DMS79 8.33333 3.05889 0.215199239999488 0.84879578995011 DataSet_03_016
MMRN1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.645501 -0.631509 0.54121549585747 0.923836513763911 DataSet_03_025
MMRN1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.23081 -2.11522 0.0885217454153556 0.559102562010572 DataSet_03_026
MMRN1 CEBPB siRNA Embryo hESC 0.606901 -0.720467 0.482289993764364 0.78788892614962 DataSet_03_049
MMRN1 GATA4 siRNA Stomach AGS 0.379529 -1.39772 0.284820736240867 0.860324774647388 DataSet_03_105
MMRN1 GATA4 siRNA Stomach KatoIII 0.345288 -1.53413 0.0579829352848481 0.868062487809359 DataSet_03_106
MMRN1 GATA4 siRNA Stomach YCC3 0.429026 -1.22086 0.235446901678919 0.751568421672517 DataSet_03_107
MMRN1 HNF4a siRNA Liver HepG2 0.607143 -0.719892 0.495786519253875 0.913013996130111 DataSet_03_126
MMRN1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 4.54874 2.18547 0.330642750732601 0.999948959532916 DataSet_03_134
MMRN1 KLF5 siRNA Stomach YCC3 0.2982 -1.74565 0.220121647628884 0.586075356402869 DataSet_03_151
MMRN1 MAF siRNA Lymph Lymphatic endothelial cells 1.55539 0.637277 0.127851902641949 0.816720674716982 DataSet_03_154
MMRN1 MEF2D shRNA Liver HuH7 1.55008 0.632339 - - DataSet_03_162
MMRN1 MTA2 siRNA Stomach SGC-7901 1.92043 0.941432 - - DataSet_03_169
MMRN1 MYB siRNA Cord_Blood CD34+ progenitor cells 1.86735 0.900993 - - DataSet_03_170
MMRN1 MYC siRNA Colon HT29 19.318 4.27187 - - DataSet_03_177
MMRN1 PPARG siRNA Peripheral_blood GM-CSF Macrophage 0.559936 -0.836667 0.000796476035129407 0.771788785531601 DataSet_03_214
MMRN1 PRRX1 CRISPR Neuroblastoma 691-MES 1.90959 0.933264 0.0594826900866267 0.89189998148014 DataSet_03_217
MMRN1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 3.92308 1.97199 - - DataSet_03_246
MMRN1 SP1 siRNA Ovary OVSAYO 0.473753 -1.07779 0.0037403747537913 0.0938348845935413 DataSet_03_251
MMRN1 STAT3 CRISPR Embryo hESC 15.3279 3.93808 0.00258858451913519 0.036516980347139 DataSet_03_258
MMRN1 TFAP2C siRNA Mammary_gland MCF7 2.14982 1.10422 0.401919185247193 0.700036994814442 DataSet_03_274
MMRN1 TFE3 siRNA Kidney UOK257-2 0.0800188 -3.64352 - - DataSet_03_275
MMRN1 SMAD5 CRISPR Liver HepG2 0.153846 -2.70044 0.0834760102926728 0.467283541642673 DataSet_04_036
MMRN1 SRPK2 CRISPR Liver HepG2 1.66667 0.736966 0.188365275728583 0.384524600771168 DataSet_04_037
MMRN1 ZNF574 CRISPR Liver HepG2 0.153846 -2.70044 0.098873652788305 0.212778199570025 DataSet_04_041
MMRN1 CALR shRNA Liver HepG2 3 1.58496 0.845757463754948 0.914661901021958 DataSet_04_053
MMRN1 CNOT7 shRNA Liver HepG2 0.333333 -1.58496 0.688221310410636 0.775251238256253 DataSet_04_051
MMRN1 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.480472337887004 0.873529287605431 DataSet_04_047
MMRN1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.618062992385453 0.917455222252807 DataSet_04_076
MMRN1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.920488752644846 1 DataSet_04_077
MMRN1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.926401189199421 0.973965380711594 DataSet_02_38
MMRN1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.921487806554394 0.960584600082578 DataSet_02_14
MMRN1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 4 2 0.636572164628028 0.783059971177446 DataSet_02_34
MMRN1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 12 3.58496 0.439928950271829 0.774084633797768 DataSet_02_75
MMRN1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.756517458616141 0.948752568314638 DataSet_02_45
MMRN1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.932145094861815 0.966812373291597 DataSet_02_35
MMRN1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.75 0.807355 0.915228730923899 0.960280935629551 DataSet_02_32
MMRN1 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.612585758517162 0.751594287777739 DataSet_02_47
MMRN1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.571429 -0.807355 0.866643604247831 0.989454336211367 DataSet_02_49
MMRN1 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 13 3.70044 0.107618260900881 0.237955932436393 DataSet_02_43
MMRN1 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2 1 0.853307185942204 0.926935609239426 DataSet_02_33
MMRN1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6.5 2.70044 0.314771442357343 0.484573082979987 DataSet_02_53
MMRN1 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.363636 -1.45943 0.646265669542809 0.89077579567287 DataSet_04_065
MMRN1 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.617147125498887 0.819301997830477 DataSet_04_062
MMRN1 CNOT3 shRNA Lung A549 0.445487 -1.16654 1.719326e-01 0.8830540 DataSet_03_340
MMRN1 ACTR5 siRNA Muscle RD 0.46123 -1.11644 - - DataSet_03_343
MMRN1 INO80 siRNA Muscle RD 0.268314 -1.89801 - - DataSet_03_344
MMRN1 AEBP1 siRNA Central_nervous_system U87MG 0.607701 -0.718566 5.045476e-01 0.9999434 DataSet_03_338
MMRN1 EZH2 shRNA Mammary_gland LM2 1.52859 0.612204 9.417294e-01 9.915113e-01 DataSet_03_350
MMRN1 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.74002 1.45419 1.066404e-02 1.458075e-01 DataSet_03_359
MMRN1 NCOA2 siRNA Uterus endometrial stromal cells 0.465714 -1.10248 0.7935828618 1 DataSet_03_360
MMRN1 MYC siRNA Peripheral_blood T lymphocyte 1.6908 0.757708 5.134216e-02 0.209122050 DataSet_03_363
MMRN1 ZNF148 shRNA Mammary_gland MDA-MB-231 0.1164 -3.10284 4.113015e-01 0.632435170 DataSet_03_366
MMRN1 TPR shRNA Bone_marrow U2OS 4.32876 2.11395 5.875647e-01 8.986068e-01 DataSet_03_370
MMRN1 NFKBIA shRNA Bone_marrow U2OS 0.0332084 -4.91231 8.833826e-01 0.95084525 DataSet_03_389
MMRN1 TLE4 CRISPR Lymph CAR T Cell 1.64564 0.718645 7.731191e-03 0.11918119 DataSet_03_398
MMRN1 TFAP2A knockout Embryo H9 62 5.9542 3.332017e-04 0.01947297 DataSet_03_405
MMRN1 CHD1 shRNA Prostate LNCaP 0.454545 -1.1375 8.122984e-02 5.673170e-01 DataSet_03_407
MMRN1 MAP3K7 shRNA Prostate LNCaP 2.27273 1.18442 3.010925e-02 1.544762e-01 DataSet_03_408
MMRN1 PRDM1 CRISPR Lymph CD8+ T cells 0.594771 -0.749593 - - DataSet_03_421
MMRN1 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.185567 -2.42999 - - DataSet_03_422
MMRN1 USP7 shRNA Skin xenograft cells 0.377095 -1.407 0.35553189 0.4901191 DataSet_03_431
MMRN1 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.223619 -2.16088 - - DataSet_03_432
MMRN1 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.33333 1.22239 7.194300e-02 0.488322122 DataSet_03_434
MMRN1 POU2AF1 CRISPR Lymph SUDHL4 6.5 2.70044 4.385029e-02 0.114075096 DataSet_03_435
MMRN1 CIC knockout Brain Immortalized Astrocyte Cells 2.5 1.32193 5.166664e-01 8.280201e-01 DataSet_03_438
MMRN1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.51445 0.598795 2.337321e-01 0.90558273 DataSet_03_439
MMRN1 CBX2 siRNA Mammary_gland MCF7 0.352463 -1.50446 7.933920e-01 0.8773012091 DataSet_03_451
MMRN1 OGT siRNA Embryo BeWo cells 0.333333 -1.58496 1.388280e-01 0.66237450 DataSet_03_453
MMRN1 HAND1 siRNA Placenta HPMVEC 0.583333 -0.777608 5.945856e-01 0.9463341 DataSet_03_459
MMRN1 TXNIP shRNA Cord_Blood CD34+ cells 2.4466 1.29078 - - DataSet_03_461
MMRN1 TXNIP shRNA Cord_blood ST3 4.11111 2.03953 9.315852e-03 0.1503491032 DataSet_03_462
MMRN1 PARP1 knockout Embryo_kidney HEK293a 6.25 2.64386 1.653924e-01 2.965635e-01 DataSet_03_464
MMRN1 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.5385167 0.954283 DataSet_04_071
Regulation Region
 
T(co)Fs that significantly regulate TFAP2A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of MMRN1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines