Gene Overview
| Target Gene: | Mttp |
| NCBI Official Symbol: | Mttp |
| Entrez ID: | 17777 |
| Ensembl ID: | ENSMUSG00000028158 |
| Gene Full Name: | microsomal triglyceride transfer protein |
| Strand: | - |
| Gene Locus: | 3 G3|3 64.06 cM |
| External Links: |
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Mttp Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Mttp
T(co)Fs
that Repress Mttp
The Intensity of the Gene Regulated by T(co)Fs:
Mttp-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Mttp | Adnp | knockout | Embryo | Whole embryonic body | 3.01637 | 1.59281 | 0.00269075588046251 | 0.242443615071769 | DataSet_11_001 |
| Mttp | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 18.4266 | 4.20371 | 2.50168054659321e-05 | 0.00200711737289372 | DataSet_11_010 |
| Mttp | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.85859 | 0.894205 | 0.118378876102648 | 0.489309706037526 | DataSet_11_014 |
| Mttp | Bhlha9 | knockout | Limb | Whole limb bud | 3.10276 | 1.63355 | - | - | DataSet_11_016 |
| Mttp | Dmrt1 | knockout | Testis | Juvenile testes | 1.92484 | 0.944738 | 0.0423183219193446 | 0.932139260123802 | DataSet_11_026 |
| Mttp | Dmrt1 | knockout | Testis | Juvenile testes | 1.61045 | 0.687467 | 0.0507983907087752 | 0.830739734023206 | DataSet_11_028 |
| Mttp | Foxp1 | knockout | Eye | Lens | 0.635155 | -0.654819 | - | - | DataSet_11_044 |
| Mttp | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 0.388267 | -1.36488 | 0.0213843135034224 | 0.987135756219234 | DataSet_11_048 |
| Mttp | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 1.55347 | 0.63549 | - | - | DataSet_11_054 |
| Mttp | Hsf4 | knockout | Eye | Lens | 0.52797 | -0.921471 | 0.509886182861 | 0.987999303842427 | DataSet_11_058 |
| Mttp | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 2.70077 | 1.43337 | 0.000829623504722956 | 0.0663226538175386 | DataSet_11_065 |
| Mttp | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.477788 | -1.06556 | 0.303478074458744 | 0.995635220774426 | DataSet_11_081 |
| Mttp | Nfil3 | knockout | Bone_marrow | Prepro NK cells | 0.608964 | -0.715571 | 0.126994618076051 | 0.592103803193821 | DataSet_11_090 |
| Mttp | Nhlh2 | knockout | Eye | Retina | 0.61978 | -0.690173 | 0.399210411551365 | 0.562720018791796 | DataSet_11_092 |
| Mttp | Otx2 | knockout | Eye | Retina | 0.557243 | -0.843622 | 0.656819490793091 | 0.999923528647439 | DataSet_11_097 |
| Mttp | Pitx2 | knockout | Eye | Cornea | 0.229244 | -2.12505 | 0.366897728397418 | 0.689455143702524 | DataSet_11_103 |
| Mttp | Pparg | siRNA | Adipose_tissue | Preadipocytes | 2.02266 | 1.01626 | 0.131202526382018 | 0.767455672427161 | DataSet_11_105 |
| Mttp | Runx1 | knockout | Lymph | ProB cells | 1.52138 | 0.605381 | 0.0943496897079474 | 0.346837770384686 | DataSet_11_116 |
| Mttp | Runx2 | knockout | Humeri | Embryonic humeri | 2.2556 | 1.17351 | 0.17367323157616 | 0.999582830775196 | DataSet_11_119 |
| Mttp | Smad4 | siRNA | Brain | bEnd3 | 0.227031 | -2.13904 | - | - | DataSet_11_127 |
| Mttp | Smad4 | knockout | Aorta | Aortic arteries | 4.23121 | 2.08107 | 0.0834361775655042 | 0.430163996740274 | DataSet_11_128 |
| Mttp | Snai1 | knockout | Embryo | Embryoid body | 0.323928 | -1.62626 | - | - | DataSet_11_129 |
| Mttp | Sox11 | knockout | Eye | Retina | 1.73452 | 0.794541 | - | - | DataSet_11_137 |
| Mttp | Spdef | knockout | Colon | Colon | 0.0126326 | -6.3067 | 0.219346450944351 | 0.997507742354799 | DataSet_11_146 |
| Mttp | Tet2 | knockout | Kidney | Kidney | 0.32071 | -1.64066 | 0.00043623390984397 | 1 | DataSet_11_159 |
| Mttp | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.409767 | -1.28712 | 0.167779556697846 | 0.999827445128963 | DataSet_11_174 |
| Mttp | Yy1 | knockout | Intestine | Jejunum crypt epithelium | 0.655781 | -0.608715 | 0.0298774604773454 | 0.1038177932251 | DataSet_11_183 |
| Mttp | Yy1 | knockout | White_adipose_tissue | Subcutaneous white adipose tissue | 1.64029 | 0.713949 | 0.00281051480943059 | 0.212961857623889 | DataSet_11_184 |
| Mttp | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 2.63922 | 1.40011 | 0.00105244505890447 | 0.0220899850488323 | DataSet_11_185 |
| Mttp | Pogz | knockdown | Liver | fetal liver | 0.630797 | -0.664752 | 4.853811e-01 | 0.7258300 | DataSet_11_188 |
| Mttp | Cpeb1 | siRNA | Neuron | Neuro-2a | 1.50316 | 0.588002 | - | - | DataSet_11_189 |
| Mttp | Smarca4 | shRNA | Embryo | ES cells | 1.56957 | 0.650366 | - | - | DataSet_11_224 |
| Mttp | Smarca4 | shRNA | Embryo | ES cells | 1.56957 | 0.650366 | - | - | DataSet_11_225 |
| Mttp | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 1.66117 | 0.732202 | 3.577568e-02 | 1.0000000 | DataSet_11_208 |
| Mttp | Dnmt3a | siRNA | Embryo | iPSC | 0.397111 | -1.33238 | - | - | DataSet_11_241 |
| Mttp | Twist1 | knockout | Bone_marrow | stromal cells | 4.3681 | 2.12701 | - | - | DataSet_11_244 |
| Mttp | Dnmt1 | siRNA | Embryo | Embryo | 0.367647 | -1.44361 | - | - | DataSet_11_248 |
| Mttp | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.525588 | -0.927996 | 1.678849e-02 | 6.868745e-02 | DataSet_11_250 |
| Mttp | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 1.97684 | 0.983198 | 1.431909e-03 | 0.025688208 | DataSet_11_252 |
| Mttp | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 0.653388 | -0.613987 | 2.834613e-01 | 0.54923495 | DataSet_11_267 |
| Mttp | Dux | knockout | Embryo | Embryo | 0.477036 | -1.06783 | 8.318524e-01 | 9.033142e-01 | DataSet_11_269 |
| Mttp | Kat6b | shRNA | Bone_marrow | LT-HSCs | 1.75758 | 0.813587 | 2.164822e-01 | 0.6076680 | DataSet_11_271 |
| Mttp | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 10.585 | 3.40394 | 1.784798e-01 | 0.81420760 | DataSet_11_272 |
| Mttp | Dux | knockout | Embryo | Embryo | 0.477036 | -1.06783 | 8.318523e-01 | 9.032738e-01 | DataSet_11_273 |
| Mttp | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 0.643172 | -0.636724 | 1.938313e-01 | 0.9643594 | DataSet_11_274 |
| Mttp | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.412682 | -1.2769 | 7.046548e-07 | 2.116754e-05 | DataSet_11_275 |
| Mttp | Ssrp1 | CRISPR | Embryo | ES cells | 1.60473 | 0.68233 | 1.499939e-01 | 0.7762809 | DataSet_11_278 |
| Mttp | Usp7 | knockout | Embryo | ES cells | 2.11806 | 1.08274 | 8.941098e-02 | 0.5236847 | DataSet_11_279 |
| Mttp | Arid2 | knockout | Muscle | LSK | 1.67368 | 0.743027 | 1.096804e-01 | 9.751597e-01 | DataSet_11_301 |
| Mttp | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.620317 | -0.688923 | - | - | DataSet_11_305 |
| Mttp | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.654088 | -0.612443 | - | - | DataSet_11_306 |
| Mttp | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 0.613734 | -0.704315 | - | - | DataSet_11_308 |
| Mttp | Suz12 | knockout | Lung | Alveolar macrophage | 5.12 | 2.35614 | 4.151048e-02 | 0.3110778427 | DataSet_11_311 |
| Mttp | Suz12 | knockout | Lung | Alveolar macrophage | 3.632 | 1.86076 | 1.077346e-02 | 6.968048e-02 | DataSet_11_312 |
| Mttp | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 2.50118 | 1.32261 | - | - | DataSet_11_313 |
| Mttp | Actl6a | knockout | Nerve | sciatic nerve | 1.56106 | 0.642528 | 1.772490e-02 | 0.189208495 | DataSet_11_314 |
| Mttp | Satb2 | knockout | Colon | Intestine epithelium | 42.9631 | 5.42503 | 2.748200e-07 | 0.0003569178 | DataSet_11_316 |
| Mttp | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.180879 | -2.46691 | 2.842957e-01 | 0.6567869602 | DataSet_11_317 |
| Mttp | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.416149 | -1.26483 | 2.791442e-01 | 0.7527440 | DataSet_11_318 |
| Mttp | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.556923 | -0.84445 | 7.747881e-01 | 0.9372442 | DataSet_11_321 |
| Mttp | Setdb1 | shRNA | Neuron | NE-4C | 0.243472 | -2.03817 | - | - | DataSet_11_323 |
| Mttp | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.595532 | -0.747749 | 4.944452e-02 | 2.397949e-01 | DataSet_11_332 |
| Mttp | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.371963 | -1.42677 | 1.851192e-03 | 0.009790412 | DataSet_11_340 |
| Mttp | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 2.87769 | 1.52491 | 0.0642780347 | 0.1712697 | DataSet_11_341 |
| Mttp | Hnrnpk | siRNA | Embryo | ES cells | 0.359959 | -1.4741 | 7.073603e-04 | 0.005947432 | DataSet_11_342 |
| Mttp | Pcbp1 | shRNA | Thymus | Th1 | 3 | 1.58496 | 2.037844e-01 | 0.47636835 | DataSet_11_343 |
Regulation Region
Expression Atlas of Mttp