Gene Overview
| Target Gene: | Pdzk1 |
| NCBI Official Symbol: | Pdzk1 |
| Entrez ID: | 59020 |
| Ensembl ID: | ENSMUSG00000038298 |
| Gene Full Name: | PDZ domain containing 1 |
| Strand: | + |
| Gene Locus: | 3|3 F2.1 |
| External Links: |
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Pdzk1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Pdzk1
T(co)Fs
that Repress Pdzk1
The Intensity of the Gene Regulated by T(co)Fs:
Pdzk1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Pdzk1 | Adnp | knockout | Embryo | Whole embryonic body | 4.89813 | 2.29223 | 0.0390194531987266 | 0.392852162829747 | DataSet_11_001 |
| Pdzk1 | Atf3 | knockout | Mammary_gland | Breast tumor-associated macrophage | 0.624788 | -0.678562 | 0.092819716368291 | 1 | DataSet_11_006 |
| Pdzk1 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 23.9622 | 4.58269 | 0.000140081059134533 | 0.00275781940136008 | DataSet_11_010 |
| Pdzk1 | Bhlha9 | knockout | Limb | Whole limb bud | 18.52 | 4.21101 | - | - | DataSet_11_016 |
| Pdzk1 | Cebpb | knockout | Mammary_gland | Mammary epithlial cells (MECs) | 1.57462 | 0.655 | 0.118917961490063 | 0.999788745984441 | DataSet_11_020 |
| Pdzk1 | Dmrt1 | knockout | Testis | Juvenile testes | 2.40609 | 1.26669 | 0.00202003102325161 | 0.777059806662477 | DataSet_11_026 |
| Pdzk1 | Dmrt1 | knockout | Testis | Testes | 7.0545 | 2.81854 | 0.000504716420631968 | 0.025285805024946 | DataSet_11_029 |
| Pdzk1 | Dmrt1 | knockout | Testis | Testes | 7.0545 | 2.81854 | 0.000504716420631968 | 0.025285805024946 | DataSet_11_032 |
| Pdzk1 | E2f4 | knockout | Brain | Forebrain | 5.02448 | 2.32897 | - | - | DataSet_11_033 |
| Pdzk1 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.269939 | -1.8893 | 0.25372526270309 | 0.534699824601178 | DataSet_11_035 |
| Pdzk1 | Esrrb | shRNA | Embryo | ES cells | 11.0007 | 3.45953 | - | - | DataSet_11_039 |
| Pdzk1 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.527116 | -0.923807 | - | - | DataSet_11_047 |
| Pdzk1 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 1.5513 | 0.633482 | 0.217560251313124 | 0.987135756219234 | DataSet_11_048 |
| Pdzk1 | Gfi1 | knockout | Cord_Blood | T-cells | 0.431085 | -1.21396 | 0.00280570696934999 | 0.134932763585012 | DataSet_11_053 |
| Pdzk1 | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 2.08688 | 1.06135 | - | - | DataSet_11_054 |
| Pdzk1 | Hsf4 | knockout | Eye | Lens | 0.167838 | -2.57486 | 0.0671079587532494 | 0.987999303842427 | DataSet_11_058 |
| Pdzk1 | Irf6 | knockout | Skin | Skin | 0.641406 | -0.640691 | 0.671349322941527 | 0.861645027919464 | DataSet_11_062 |
| Pdzk1 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 2 | 1 | 2.96608172762072e-05 | 0.144894803340097 | DataSet_11_064 |
| Pdzk1 | Lhx8 | knockout | Gonads | Oocytes | 0.141545 | -2.82067 | 0.000942491511530432 | 0.549969977297772 | DataSet_11_069 |
| Pdzk1 | Lhx8 | knockout | Ovary | Ovary | 0.120591 | -3.05181 | 4.23245264919369e-05 | 0.0100703454019506 | DataSet_11_070 |
| Pdzk1 | Lmx1b | knockout | Kidney | Kidney | 0.215144 | -2.21662 | 4.65987301634501e-05 | 0.0121313898960461 | DataSet_11_072 |
| Pdzk1 | Mafg | knockout | Embryo | Whole embryo | 0.473879 | -1.07741 | 0.181611582479834 | 1 | DataSet_11_073 |
| Pdzk1 | Neurod1 | knockout | Eye | Pineal gland | 0.617391 | -0.695743 | 0.307860409736415 | 0.9983937273602 | DataSet_11_089 |
| Pdzk1 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 1.91795 | 0.939567 | 0.70707282064184 | 0.956537819290844 | DataSet_11_094 |
| Pdzk1 | Nrf1 | knockdown | Liver | Liver | 1.53387 | 0.617175 | 0.0125188655106161 | 0.0512519223102299 | DataSet_11_096 |
| Pdzk1 | Pax6 | knockout | Embryo | Surface ectoderm | 0.599128 | -0.739063 | 0.0823284188741535 | 0.655056690657349 | DataSet_11_101 |
| Pdzk1 | Runx1 | knockout | Bone_marrow | KSL cells | 0.653426 | -0.613905 | 0.444292885636291 | 0.976590985144109 | DataSet_11_115 |
| Pdzk1 | Runx1 | knockout | Lymph | ProB cells | 1.57085 | 0.651548 | 0.129576353564396 | 0.418687950163594 | DataSet_11_116 |
| Pdzk1 | Sall1 | knockout | Kidney | Kidney | 2.86379 | 1.51793 | 0.000246110598843709 | 0.264977351869671 | DataSet_11_121 |
| Pdzk1 | Sall1 | knockout | Kidney | Kidney | 0.586429 | -0.769972 | 0.0700443131351054 | 0.820560263049813 | DataSet_11_122 |
| Pdzk1 | Smad4 | siRNA | Brain | bEnd3 | 6.23432 | 2.64023 | - | - | DataSet_11_127 |
| Pdzk1 | Smad4 | knockout | Aorta | Aortic arteries | 8.48943 | 3.08567 | 0.131901609495007 | 0.525806512115307 | DataSet_11_128 |
| Pdzk1 | Sohlh1 | knockout | Ovary | Ovary | 2.32101 | 1.21475 | 1.14362252082017e-06 | 5.87385777380666e-05 | DataSet_11_134 |
| Pdzk1 | Sohlh2 | knockout | Ovary | Ovary | 2.56937 | 1.36142 | 1.32117241369062e-07 | 9.80702081074165e-06 | DataSet_11_135 |
| Pdzk1 | Sox11 | knockout | Eye | Retina | 5.57143 | 2.47805 | - | - | DataSet_11_137 |
| Pdzk1 | Spdef | knockout | Colon | Colon | 0.00229548 | -8.76699 | 0.274889463574687 | 0.997507742354799 | DataSet_11_146 |
| Pdzk1 | Spdef | knockout | Stomach | Stomach | 3.44813 | 1.78581 | 0.24130209458054 | 0.895948589880502 | DataSet_11_147 |
| Pdzk1 | Tbx1 | knockout | Ear | Otic vesicles | 0.652147 | -0.616731 | 0.260244111634454 | 0.996209135879357 | DataSet_11_154 |
| Pdzk1 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.245052 | -2.02884 | 0.0509863038042907 | 0.999827445128963 | DataSet_11_174 |
| Pdzk1 | Vdr | knockout | Skin | Skin | 1.99869 | 0.999053 | - | - | DataSet_11_176 |
| Pdzk1 | Wt1 | siRNA | Embryo_kidney | LB-22 | 2.1177 | 1.08249 | 0.260821099089577 | 0.509535451538902 | DataSet_11_179 |
| Pdzk1 | Yy1 | knockout | Intestine | Jejunum crypt epithelium | 0.237569 | -2.07358 | 0.000168672872936199 | 0.00711382361079824 | DataSet_11_183 |
| Pdzk1 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 0.0376295 | -4.73199 | 0.0605390569436802 | 0.199092992467066 | DataSet_11_185 |
| Pdzk1 | Pogz | knockdown | Liver | fetal liver | 0.259276 | -1.94744 | 1.798893e-02 | 0.3075683 | DataSet_11_188 |
| Pdzk1 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.448492 | -1.15684 | - | - | DataSet_11_189 |
| Pdzk1 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 0.376707 | -1.40849 | 8.652664e-05 | 6.558384e-04 | DataSet_11_236 |
| Pdzk1 | Mapk9 | knockout | Knee | Mouse total knee | 0.448558 | -1.15663 | 2.482984e-02 | 0.176511200 | DataSet_11_237 |
| Pdzk1 | Tet1 | shRNA | Embryo | ES cells | 0.605351 | -0.724156 | 4.620188e-02 | 0.59838305 | DataSet_11_191 |
| Pdzk1 | Dnmt3l | shRNA | Embryo | ES cells | 2.18726 | 1.12912 | 3.861402e-02 | 8.725158e-02 | DataSet_11_231 |
| Pdzk1 | Smarca4 | shRNA | Embryo | ES cells | 0.192915 | -2.37396 | - | - | DataSet_11_224 |
| Pdzk1 | Smarca4 | shRNA | Embryo | ES cells | 0.192915 | -2.37396 | - | - | DataSet_11_225 |
| Pdzk1 | Ncl | siRNA | Embryo | ES cells | 0.632302 | -0.661313 | 1.021945e-01 | 0.4596962563 | DataSet_11_240 |
| Pdzk1 | Eed | knockout | Brain | Forebrain | 0.571181 | -0.807981 | 3.848083e-01 | 7.492072e-01 | DataSet_11_258 |
| Pdzk1 | Dux | knockout | Embryo | Embryo | 5.13321 | 2.35986 | 1.666357e-03 | 1.037165e-02 | DataSet_11_269 |
| Pdzk1 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 0.571429 | -0.807355 | 2.299808e-01 | 0.6076680 | DataSet_11_271 |
| Pdzk1 | Dux | knockout | Embryo | Embryo | 5.13321 | 2.35986 | 1.666351e-03 | 1.037061e-02 | DataSet_11_273 |
| Pdzk1 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 1.6 | 0.678072 | 1.779589e-01 | 0.6936949 | DataSet_11_283 |
| Pdzk1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.86885 | 0.902153 | - | - | DataSet_11_285 |
| Pdzk1 | Fli1 | CRISPR | Lymph | CD8 T cells | 0.46 | -1.12029 | 3.346727e-01 | 0.9999740103 | DataSet_11_288 |
| Pdzk1 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 1.79696 | 0.84556 | 2.688181e-01 | 6.625308e-01 | DataSet_11_289 |
| Pdzk1 | Kmt2d | CRISPR | Liver | MA1L | 0.365735 | -1.45113 | 3.370682e-01 | 5.869974e-01 | DataSet_11_290 |
| Pdzk1 | Kmt2d | CRISPR | Liver | MA1L | 0.377665 | -1.40482 | 3.528016e-01 | 5.914425e-01 | DataSet_11_291 |
| Pdzk1 | Tfap2a | knockout | Brain | Brain | 1.88889 | 0.917538 | 0.1172119126 | 0.9599640 | DataSet_11_295 |
| Pdzk1 | Ssrp1 | CRISPR | Embryo | ES cells | 1.75168 | 0.808738 | 5.430540e-02 | 0.28823884 | DataSet_11_296 |
| Pdzk1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 0.415842 | -1.26589 | 8.950869e-01 | 9.807509e-01 | DataSet_11_297 |
| Pdzk1 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.49659 | -1.00987 | 5.210763e-01 | 0.9999903 | DataSet_11_299 |
| Pdzk1 | Satb2 | CRISPR | Colon | Colon organoid | 2.14286 | 1.09954 | 3.981443e-01 | 0.6858571 | DataSet_11_304 |
| Pdzk1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.45068 | -1.14982 | - | - | DataSet_11_305 |
| Pdzk1 | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 3.5 | 1.80736 | 3.356270e-01 | 0.85686681 | DataSet_11_309 |
| Pdzk1 | Suz12 | knockout | Lung | Alveolar macrophage | 1.91204 | 0.935114 | 4.376256e-02 | 1.119451e-01 | DataSet_11_312 |
| Pdzk1 | Satb2 | knockout | Colon | Intestine epithelium | 48.2 | 5.59096 | 5.908192e-05 | 0.0093060440 | DataSet_11_316 |
| Pdzk1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.574597 | -0.799378 | 1.741485e-02 | 3.125684e-01 | DataSet_11_319 |
| Pdzk1 | Snai1 | knockdown | Heart | Heart | 0.492815 | -1.02088 | 3.765900e-01 | 0.56276955 | DataSet_11_326 |
| Pdzk1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.555556 | -0.847997 | 2.602511e-01 | 5.790387e-01 | DataSet_11_332 |
| Pdzk1 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 0.4 | -1.32193 | 1.170527e-01 | 0.65453156 | DataSet_11_337 |
| Pdzk1 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 1.8 | 0.847997 | 7.682521e-01 | 0.95567217 | DataSet_11_338 |
| Pdzk1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.6 | -0.736966 | 2.620009e-01 | 0.419390982 | DataSet_11_340 |
| Pdzk1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 6.69355 | 2.74277 | 0.0077986488 | 0.1712697 | DataSet_11_341 |
| Pdzk1 | Hnrnpk | siRNA | Embryo | ES cells | 0.23124 | -2.11253 | 2.090422e-02 | 0.046896365 | DataSet_11_342 |
| Pdzk1 | Pcbp1 | shRNA | Thymus | Th1 | 0.636364 | -0.652077 | 2.223837e-01 | 0.47636835 | DataSet_11_343 |
| Pdzk1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.65131 | 0.723611 | 4.717056e-01 | 7.072419e-01 | DataSet_11_344 |
| Pdzk1 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 3.5 | 1.80735 | 3.356270e-01 | 0.85686681 | DataSet_11_347 |
| Pdzk1 | Tbx20 | CRISPR | Heart | primary cardiac fibroblasts | 2.5 | 1.32193 | 3.787500e-01 | 1.00000000 | DataSet_11_348 |
Regulation Region
Expression Atlas of Pdzk1