Gene Overview
| Target Gene: | Pls3 |
| NCBI Official Symbol: | Pls3 |
| Entrez ID: | 102866 |
| Ensembl ID: | ENSMUSG00000016382 |
| Gene Full Name: | plastin 3 (T-isoform) |
| Strand: | - |
| Gene Locus: | X|X A7.3 |
| External Links: |
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Pls3 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Pls3
T(co)Fs
that Repress Pls3
The Intensity of the Gene Regulated by T(co)Fs:
Pls3-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Pls3 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 0.140276 | -2.83366 | 0.000787305667798929 | 0.00539198884310218 | DataSet_11_010 |
| Pls3 | Bhlha9 | knockout | Limb | Whole limb bud | 1.59102 | 0.669949 | - | - | DataSet_11_016 |
| Pls3 | Cbfb | knockdown | Peripheral_blood | Peripheral CD4+CD25hi cells | 0.428292 | -1.22333 | 0.00668800633356171 | 0.416506100294684 | DataSet_11_017 |
| Pls3 | Cebpb | shRNA | Mammary_gland | 4T1 mammary tumor cells | 0.59812 | -0.741493 | 0.690070735968671 | 0.999984070881864 | DataSet_11_022 |
| Pls3 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.65221 | 0.724401 | 0.165124245777083 | 0.453261246911393 | DataSet_11_035 |
| Pls3 | Gfi1 | knockout | Cord_Blood | T-cells | 5.7831 | 2.53184 | 0.000179752661146571 | 0.0491447974248732 | DataSet_11_053 |
| Pls3 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.608016 | -0.71782 | 0.000472771763371799 | 0.00847748993759525 | DataSet_11_066 |
| Pls3 | Lhx8 | knockout | Gonads | Oocytes | 0.552114 | -0.856961 | 0.627548642831318 | 0.998630964563827 | DataSet_11_069 |
| Pls3 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 0.321418 | -1.63748 | 0.000163703527484644 | 0.00273599908425382 | DataSet_11_076 |
| Pls3 | Nhlh2 | knockout | Eye | Retina | 0.40447 | -1.30589 | 0.0979869317410712 | 0.523726874680013 | DataSet_11_092 |
| Pls3 | Otx2 | knockout | Eye | Retina | 0.57802 | -0.79081 | 0.756757603561881 | 0.999923528647439 | DataSet_11_097 |
| Pls3 | Pitx2 | knockout | Eye | Cornea | 2.57552 | 1.36486 | 0.0437563472071034 | 0.3192284473325 | DataSet_11_103 |
| Pls3 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 1.76875 | 0.822734 | 0.131307476642902 | 0.767455672427161 | DataSet_11_105 |
| Pls3 | Runx1 | knockout | Lymph | ProB cells | 1.69941 | 0.765038 | 0.0653969583754825 | 0.27722765798045 | DataSet_11_116 |
| Pls3 | Sall4 | shRNA | Embryo | ES cells | 1.50574 | 0.59047 | 0.18232107724852 | 0.999840995136314 | DataSet_11_123 |
| Pls3 | Smad4 | knockout | Aorta | Aortic arteries | 0.431307 | -1.21321 | 0.0208441859783304 | 0.223541500194701 | DataSet_11_128 |
| Pls3 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 1.55808 | 0.639765 | 0.10700217399134 | 0.999994003527217 | DataSet_11_132 |
| Pls3 | Sohlh2 | knockout | Ovary | Ovary | 0.631053 | -0.664167 | 1.8901738938224e-05 | 0.000364316367385128 | DataSet_11_135 |
| Pls3 | Sox10 | siRNA | Melanoma | B16F10 | 0.591921 | -0.756524 | 0.0091555713630806 | 0.0486558505610502 | DataSet_11_136 |
| Pls3 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.656801 | -0.606472 | 0.0297158153937858 | 0.101271069188714 | DataSet_11_153 |
| Pls3 | Thap1 | knockout | Brain | Cerebellum | 0.613774 | -0.70422 | 0.0233859592632923 | 0.105006022117705 | DataSet_11_164 |
| Pls3 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.66529 | -0.587944 | 0.28594919285344 | 0.999827445128963 | DataSet_11_174 |
| Pls3 | Vdr | knockout | Skin | Skin | 1.67052 | 0.740295 | - | - | DataSet_11_175 |
| Pls3 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 0.398578 | -1.32706 | 0.0800031216732096 | 0.233732500508169 | DataSet_11_185 |
| Pls3 | Pogz | knockdown | Liver | fetal liver | 0.366715 | -1.44727 | 8.125390e-03 | 0.2986806 | DataSet_11_188 |
| Pls3 | Hipk2 | knockout | Heart | cardiac tissue | 0.651917 | -0.61724 | 8.686279e-04 | 5.679729e-02 | DataSet_11_238 |
| Pls3 | Tet1 | shRNA | Embryo | ES cells | 0.628703 | -0.669551 | 1.919693e-04 | 3.060572e-03 | DataSet_11_211 |
| Pls3 | Tet1 | shRNA | Embryo | ES cells | 0.628703 | -0.669551 | 1.919693e-04 | 3.060572e-03 | DataSet_11_212 |
| Pls3 | Tet1 | knockout | Embryo | ES cells | 1.7532 | 0.80999 | 1.888072e-03 | 0.13420642 | DataSet_11_216 |
| Pls3 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.268963 | -1.89452 | 4.374269e-04 | 8.393451e-03 | DataSet_11_192 |
| Pls3 | Ezh2 | knockdown | Brain | Brain | 1.63538 | 0.709628 | 4.371540e-02 | 0.2353691860 | DataSet_11_221 |
| Pls3 | Dnmt1 | knockout | Liver | Liver | 0.631493 | -0.663162 | 3.736595e-05 | 5.331268e-03 | DataSet_11_232 |
| Pls3 | Smarca4 | shRNA | Embryo | ES cells | 0.575496 | -0.797123 | - | - | DataSet_11_224 |
| Pls3 | Smarca4 | shRNA | Embryo | ES cells | 0.575496 | -0.797123 | - | - | DataSet_11_225 |
| Pls3 | Crebbp | knockout | Spleen | Germinal center B cells | 2.81557 | 1.49343 | 3.693672e-04 | 0.059171420 | DataSet_11_227 |
| Pls3 | Ncl | siRNA | Embryo | ES cells | 0.522128 | -0.937524 | 3.602694e-02 | 0.3424054118 | DataSet_11_240 |
| Pls3 | Dnmt3a | siRNA | Embryo | iPSC | 1.58522 | 0.664684 | - | - | DataSet_11_241 |
| Pls3 | Twist1 | knockout | Bone_marrow | stromal cells | 0.0400122 | -4.64342 | - | - | DataSet_11_244 |
| Pls3 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 0.0425663 | -4.55415 | 9.608562e-06 | 2.869287e-04 | DataSet_11_249 |
| Pls3 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 1.54858 | 0.630945 | 0.0237911670 | 0.3808902 | DataSet_11_256 |
| Pls3 | Fubp1 | shRNA | Bone_marrow | BM cells | 2.37798 | 1.24973 | 1.796805e-03 | 0.143008345 | DataSet_11_262 |
| Pls3 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 2.9868 | 1.5786 | 4.311158e-04 | 0.03325850 | DataSet_11_267 |
| Pls3 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 1.61823 | 0.69442 | 9.432084e-02 | 0.5927415 | DataSet_11_271 |
| Pls3 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.237648 | -2.0731 | 6.009762e-01 | 0.90398793 | DataSet_11_272 |
| Pls3 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 2.17593 | 1.12163 | 2.544413e-01 | 0.9643594 | DataSet_11_274 |
| Pls3 | Ssrp1 | CRISPR | Embryo | ES cells | 1.57968 | 0.659629 | 1.288002e-01 | 0.7762809 | DataSet_11_278 |
| Pls3 | Fli1 | CRISPR | Lymph | CD8 T cells | 1.80952 | 0.85561 | 3.123139e-01 | 0.9999740103 | DataSet_11_288 |
| Pls3 | Phf8 | knockout | prostate | Prostate | 0.63198 | -0.662048 | 0.0399153764 | 0.2459109 | DataSet_11_298 |
| Pls3 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.607477 | -0.719099 | - | - | DataSet_11_305 |
| Pls3 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 6.1052 | 2.61004 | 3.357046e-01 | 0.80359421 | DataSet_11_310 |
| Pls3 | Suz12 | knockout | Lung | Alveolar macrophage | 3.20163 | 1.67881 | 1.066362e-02 | 0.1605047873 | DataSet_11_311 |
| Pls3 | Suz12 | knockout | Lung | Alveolar macrophage | 1.75496 | 0.811437 | 5.871603e-02 | 1.275120e-01 | DataSet_11_312 |
| Pls3 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 1.71429 | 0.777608 | - | - | DataSet_11_313 |
| Pls3 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 2.5 | 1.32193 | 1.737870e-01 | 0.5468457234 | DataSet_11_317 |
| Pls3 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.25 | -2 | 1.793782e-02 | 0.5174157 | DataSet_11_318 |
| Pls3 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 2.32274 | 1.21583 | 2.482452e-03 | 4.621257e-02 | DataSet_11_320 |
| Pls3 | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.399304 | -1.32444 | 7.563328e-02 | 0.8600602 | DataSet_11_321 |
| Pls3 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 1.61795 | 0.694165 | 1.761339e-01 | 0.9609895 | DataSet_11_327 |
| Pls3 | Kdm5b | siRNA | Embryo | ES cells | 0.541022 | -0.88624 | 0.2020074139 | 0.8933528 | DataSet_11_331 |
| Pls3 | Gtf2ird1 | knockout | Lip | Lip | 2.42888 | 1.28029 | 2.251891e-02 | 2.932775e-01 | DataSet_11_339 |
| Pls3 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.442872 | -1.17504 | 1.742377e-03 | 0.009677837 | DataSet_11_340 |
| Pls3 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 2.62356 | 1.39153 | 0.0780285990 | 0.1712697 | DataSet_11_341 |
| Pls3 | Pcbp1 | shRNA | Thymus | Th1 | 4 | 2 | 7.621697e-04 | 0.04701747 | DataSet_11_343 |
Regulation Region
Expression Atlas of Pls3