Gene Overview
| Target Gene: | Ptger4 |
| NCBI Official Symbol: | Ptger4 |
| Entrez ID: | 19219 |
| Ensembl ID: | ENSMUSG00000039942 |
| Gene Full Name: | prostaglandin E receptor 4 (subtype EP4) |
| Strand: | - |
| Gene Locus: | 15 A1|15 1.99 cM |
| External Links: |
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Ptger4 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Ptger4
T(co)Fs
that Repress Ptger4
The Intensity of the Gene Regulated by T(co)Fs:
Ptger4-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Ptger4 | Adnp | knockout | Embryo | Whole embryonic body | 2.67052 | 1.41712 | 0.214865337296348 | 0.576785485764522 | DataSet_11_001 |
| Ptger4 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 2.4398 | 1.28676 | 0.000943917245232674 | 0.00594303065561229 | DataSet_11_010 |
| Ptger4 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.40393 | -1.30782 | 0.00204908416982662 | 0.196095719750317 | DataSet_11_014 |
| Ptger4 | Bhlha9 | knockout | Limb | Whole limb bud | 15.4143 | 3.94619 | - | - | DataSet_11_016 |
| Ptger4 | Cbx2 | knockout | Gonads | Embryonic gonads | 4.00973 | 2.00351 | 1.38763356575427e-13 | 2.9416996509464e-10 | DataSet_11_018 |
| Ptger4 | Cebpe | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.56462 | 0.645815 | - | - | DataSet_11_023 |
| Ptger4 | Dmrt1 | knockout | Testis | Juvenile testes | 2.03435 | 1.02457 | 0.455463327991175 | 0.870546743250724 | DataSet_11_025 |
| Ptger4 | Dmrt1 | knockout | Testis | Juvenile testes | 1.93214 | 0.950203 | 0.154928320070581 | 0.830739734023206 | DataSet_11_028 |
| Ptger4 | Foxa2 | knockout | Lung | Whole lung | 1.64646 | 0.719367 | 0.0451512715238108 | 0.387425832070215 | DataSet_11_041 |
| Ptger4 | Foxp1 | knockout | Eye | Lens | 0.581395 | -0.782409 | - | - | DataSet_11_044 |
| Ptger4 | Foxq1 | siRNA | Mammary_gland | NM18 | 1.62586 | 0.701203 | 8.74226620164701e-05 | 0.0018436562363441 | DataSet_11_045 |
| Ptger4 | Gata1 | siRNA | Bone_marrow | Bone marrow-derived mast cells | 1.7074 | 0.771802 | - | - | DataSet_11_046 |
| Ptger4 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.60467 | -0.72578 | - | - | DataSet_11_047 |
| Ptger4 | Gfi1 | knockout | Macrophage_cells | RAW264.7 | 1.56895 | 0.649801 | 0.048462615665663 | 0.0929764910465007 | DataSet_11_052 |
| Ptger4 | Gfi1 | knockout | Cord_Blood | T-cells | 0.642074 | -0.639189 | 0.0740892175733584 | 0.440728560508113 | DataSet_11_053 |
| Ptger4 | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 0.572999 | -0.803395 | - | - | DataSet_11_054 |
| Ptger4 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.532779 | -0.908391 | 0.00096361995779026 | 0.066595924096686 | DataSet_11_065 |
| Ptger4 | Klf6 | shRNA | Liver | HCC | 1.66791 | 0.738043 | 0.00428161031757546 | 0.998072688143085 | DataSet_11_067 |
| Ptger4 | Lhx8 | knockout | Ovary | Ovary | 4.39002 | 2.13423 | 5.87487172190531e-05 | 0.0100703454019506 | DataSet_11_070 |
| Ptger4 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 4.08119 | 2.02899 | 4.00659112783084e-07 | 3.0000255083877e-05 | DataSet_11_076 |
| Ptger4 | Mef2a | shRNA | Muscle | C2C12 | 1.9506 | 0.963919 | 1.67733768804421e-07 | 1.60800219450377e-05 | DataSet_11_077 |
| Ptger4 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.648017 | -0.625896 | 0.262487574183563 | 0.995635220774426 | DataSet_11_081 |
| Ptger4 | Myb | shRNA | Hematopoietic | AML cells | 1.74628 | 0.804284 | 0.000663131982195009 | 0.0108783438448896 | DataSet_11_084 |
| Ptger4 | Neurod1 | knockout | Eye | Retina | 1.69043 | 0.757386 | 0.000341786271285427 | 0.00720425716740959 | DataSet_11_088 |
| Ptger4 | Nfix | shRNA | Muscle | LSK | 1.52758 | 0.611245 | 0.000989319539721268 | 0.0388237521840143 | DataSet_11_091 |
| Ptger4 | Nrf1 | knockdown | Liver | Liver | 2.16624 | 1.11519 | 0.0339890387492381 | 0.0912646721889894 | DataSet_11_096 |
| Ptger4 | Pax5 | knockout | Bone_marrow | B220+ cells | 0.418278 | -1.25747 | 0.035837124214397 | 0.27147472364164 | DataSet_11_100 |
| Ptger4 | Prdm2 | shRNA | Muscle | C2C12 | 2.01045 | 1.00752 | 0.251442162446278 | 0.945484595524129 | DataSet_11_108 |
| Ptger4 | Runx1 | knockout | Lymph | ProB cells | 0.517884 | -0.9493 | 0.014592438238127 | 0.107603370660275 | DataSet_11_116 |
| Ptger4 | Smad1 | knockout | Lung | Lung left lobe | 1.59569 | 0.67418 | 0.0359764580294691 | 0.542998753027287 | DataSet_11_126 |
| Ptger4 | Smad4 | siRNA | Brain | bEnd3 | 1.85276 | 0.889675 | - | - | DataSet_11_127 |
| Ptger4 | Smad4 | knockout | Aorta | Aortic arteries | 2.48026 | 1.31049 | 0.0371493492035104 | 0.295790927380043 | DataSet_11_128 |
| Ptger4 | Srf | knockout | Aorta | Aorta | 1.55833 | 0.64 | 0.0337501243766756 | 0.993526315825099 | DataSet_11_148 |
| Ptger4 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.375455 | -1.41329 | 0.220194939319001 | 0.924261066168849 | DataSet_11_152 |
| Ptger4 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.11291 | 1.07923 | 5.6994868693973e-05 | 0.00179382484306782 | DataSet_11_153 |
| Ptger4 | Tbx1 | knockout | Ear | Otic vesicles | 1.58109 | 0.660919 | 0.0105128256946764 | 0.557663728218115 | DataSet_11_155 |
| Ptger4 | Tet2 | knockout | Kidney | Kidney | 1.53008 | 0.613607 | 0.234218147639348 | 1 | DataSet_11_159 |
| Ptger4 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.59681 | 0.675189 | 0.141973834952943 | 0.999827445128963 | DataSet_11_174 |
| Ptger4 | Cpeb1 | siRNA | Neuron | Neuro-2a | 2.42549 | 1.27828 | - | - | DataSet_11_189 |
| Ptger4 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 6.00186 | 5.77913 | 2.227343e-01 | 10576 | DataSet_11_236 |
| Ptger4 | Mapk9 | knockout | Knee | Mouse total knee | 5.91369 | 5.82084 | 0.0928500000 | 13087 | DataSet_11_237 |
| Ptger4 | Tet1 | shRNA | Embryo | ES cells | 74.5034 | 74.8497 | -6.689886e-03 | 27395 | DataSet_11_191 |
| Ptger4 | Ncoa3 | shRNA | Embryo | ES cells | 95.3898 | 103.657 | -1.199066e-01 | 11313 | DataSet_11_194 |
| Ptger4 | Ncoa3 | shRNA | Embryo | ES cells | 95.3898 | 103.657 | -1.199066e-01 | 11313 | DataSet_11_195 |
| Ptger4 | Dnmt3l | shRNA | Embryo | ES cells | 116.529 | 113.796 | 3.423916e-02 | 27481 | DataSet_11_231 |
| Ptger4 | Bptf | knockout | Embryo | Embryonic fibroblasts | 62.2374 | 63.5116 | -2.923924e-02 | 23157 | DataSet_11_197 |
| Ptger4 | Ezh2 | knockdown | Brain | Brain | 5.58939 | 5.23084 | 0.3585520 | 9130 | DataSet_11_221 |
| Ptger4 | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 103.75 | 113.95 | -1.352896e-01 | 5022 | DataSet_11_199 |
| Ptger4 | Dnmt3b | knockout | Heart | Cardiac ventricle | 55.1726 | 53.5154 | 4.399811e-02 | 13922 | DataSet_11_205 |
| Ptger4 | Smarca4 | shRNA | Embryo | ES cells | 2.25598 | 1.17376 | - | - | DataSet_11_224 |
| Ptger4 | Smarca4 | shRNA | Embryo | ES cells | 2.25598 | 1.17376 | - | - | DataSet_11_225 |
| Ptger4 | Lin28a | knockout | Heart | Heart | 0.595842 | -0.746999 | 0.2885512431 | 0.8777652 | DataSet_11_243 |
| Ptger4 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.252335 | -1.98659 | 8.531184e-04 | 0.0220446724 | DataSet_11_245 |
| Ptger4 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 7.19802 | 2.8476 | 1.833569e-05 | 5.330085e-04 | DataSet_11_250 |
| Ptger4 | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 1.51271 | 0.597139 | 8.795783e-02 | 0.3082332 | DataSet_11_254 |
| Ptger4 | Crebbp | shRNA | Lung | preSC | 0.486486 | -1.03953 | 1.030763e-02 | 0.29946733 | DataSet_11_255 |
| Ptger4 | Eed | knockout | Brain | Forebrain | 2.86283 | 1.51744 | 1.771231e-03 | 1.039109e-01 | DataSet_11_258 |
| Ptger4 | Eed | knockout | Brain | midbrain | 3.81586 | 1.93201 | 1.162343e-03 | 1.034784e-01 | DataSet_11_260 |
| Ptger4 | Ctnnb1 | knockout | Embryo | MGE cells | 3.12886 | 1.64564 | 2.801488e-02 | 0.171116391 | DataSet_11_266 |
| Ptger4 | Dux | knockout | Embryo | Embryo | 0.500679 | -0.998043 | 2.957349e-01 | 4.809071e-01 | DataSet_11_269 |
| Ptger4 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.0444133 | -4.49287 | 1.395615e-01 | 0.81420760 | DataSet_11_272 |
| Ptger4 | Dux | knockout | Embryo | Embryo | 0.500679 | -0.998043 | 2.957348e-01 | 4.809363e-01 | DataSet_11_273 |
| Ptger4 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 1.75935 | 0.815046 | 2.907844e-01 | 0.9643594 | DataSet_11_274 |
| Ptger4 | Ssrp1 | CRISPR | Embryo | ES cells | 2.05357 | 1.03814 | 8.473201e-02 | 0.7762809 | DataSet_11_278 |
| Ptger4 | Usp7 | knockout | Embryo | ES cells | 1.9697 | 0.977974 | 8.542026e-02 | 0.5115904 | DataSet_11_279 |
| Ptger4 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 0.651466 | -0.618237 | - | - | DataSet_11_285 |
| Ptger4 | Pdx1 | CRISPR | Liver | Liver | 0.455357 | -1.13493 | 1.409577e-02 | 0.320198855 | DataSet_11_286 |
| Ptger4 | Kmt2d | CRISPR | Liver | MA1L | 1.58685 | 0.666168 | 1.307445e-03 | 1.812508e-02 | DataSet_11_290 |
| Ptger4 | Kmt2d | CRISPR | Liver | MA1L | 1.62305 | 0.69871 | 1.428256e-03 | 1.955989e-02 | DataSet_11_291 |
| Ptger4 | Setd1a | shRNA | Eye | Retina | 0.59952 | -0.738121 | 6.797827e-01 | 0.8401106613 | DataSet_11_293 |
| Ptger4 | Phf8 | knockout | prostate | Prostate | 2.61111 | 1.38466 | 0.1197795056 | 0.3606374 | DataSet_11_298 |
| Ptger4 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.60016 | -0.736582 | - | - | DataSet_11_305 |
| Ptger4 | Suz12 | knockout | Lung | Alveolar macrophage | 1.57906 | 0.659065 | 8.058137e-02 | 0.4488978797 | DataSet_11_311 |
| Ptger4 | Suz12 | knockout | Lung | Alveolar macrophage | 1.51029 | 0.594827 | 1.590717e-01 | 2.351376e-01 | DataSet_11_312 |
| Ptger4 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.470387 | -1.08808 | - | - | DataSet_11_313 |
| Ptger4 | Satb2 | knockout | Colon | Intestine epithelium | 1.57868 | 0.658719 | 1.056975e-01 | 0.4504287749 | DataSet_11_316 |
| Ptger4 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 5.64179 | 2.49615 | 5.467816e-03 | 0.0880432502 | DataSet_11_317 |
| Ptger4 | Setdb1 | shRNA | Neuron | NE-4C | 0.382187 | -1.38765 | - | - | DataSet_11_323 |
| Ptger4 | Padi2 | knockout | Testis | Testis | 2 | 1 | 1.190260e-01 | 0.9481885 | DataSet_11_324 |
| Ptger4 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 0.573964 | -0.800967 | 5.186149e-01 | 0.9609895 | DataSet_11_327 |
| Ptger4 | Kdm5b | siRNA | Embryo | ES cells | 0.207515 | -2.26871 | 0.0861035935 | 0.8933528 | DataSet_11_331 |
| Ptger4 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.430441 | -1.21611 | 1.268426e-02 | 1.117534e-01 | DataSet_11_332 |
| Ptger4 | Ezh2 | knockout | Eye | Retina | 0.46071 | -1.11807 | 0.9162394303 | 1.0000000 | DataSet_11_334 |
| Ptger4 | Atrx | knockout | Embryo | ES cells | 0.294118 | -1.76553 | - | - | DataSet_11_335 |
| Ptger4 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 0.562369 | -0.83041 | 4.125570e-02 | 0.53900308 | DataSet_11_337 |
| Ptger4 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.318467 | -1.65078 | 2.030085e-03 | 0.009953984 | DataSet_11_340 |
| Ptger4 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 3.10536 | 1.63476 | 0.0622437204 | 0.1712697 | DataSet_11_341 |
Regulation Region
Expression Atlas of Ptger4