Gene Overview
Target Gene: SLC17A8
NCBI Official Symbol: SLC17A8
Entrez ID: 246213
Ensembl ID: ENSG00000179520
Gene Full Name: solute carrier family 17 member 8
Strand: +
Gene Locus: 12q23.1
External Links:

SLC17A8 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate SLC17A8   
T(co)Fs that Repress SLC17A8
The Intensity of the Gene Regulated by T(co)Fs:
SLC17A8-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
SLC17A8 ID1 siRNA Lung H1650 0.41215 -1.27875 0.75196 0.90074 DataSet_01_118
SLC17A8 ZIC2 siRNA Pancreas PANC1 0.31168 -1.68185 - - DataSet_01_121
SLC17A8 FOXM1 siRNA Central_nervous_system U87 2.60611 1.3819 - - DataSet_01_122
SLC17A8 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.32139 1.21499 0.32677 0.99993 DataSet_01_138
SLC17A8 TP53 siRNA Lung SAECs 3.5 1.80735 0.13346 0.54386 DataSet_01_175
SLC17A8 GATA2 siRNA Prostate LNCaP 0.66207 -0.59495 0.1548 0.26778 DataSet_01_193
SLC17A8 CREB1 shRNA Parotid_gland H3118 MEC 15.4336 3.94801 0.43937 0.75425 DataSet_01_194
SLC17A8 TP63 siRNA Immortalized_keratinocyte HaCaT 5.9 2.56071 - - DataSet_01_200
SLC17A8 TP63 siRNA Head_and_neck SCC-012 2.51441 1.33022 - - DataSet_01_201
SLC17A8 TP63 siRNA Head_and_neck SCC-6 2.87404 1.52308 - - DataSet_01_202
SLC17A8 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.65164 -0.61785 - - DataSet_01_208
SLC17A8 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 3.24713 1.69916 - - DataSet_01_209
SLC17A8 BCLAF1 shRNA Colon RKO 1.75357 0.8103 - - DataSet_01_214
SLC17A8 SNAI2 shRNA Skin Primary human keratinocytes 0.46775 -1.09619 0.24786 0.38823 DataSet_01_225
SLC17A8 KLF2 shRNA Bone_marrow RPMI8226 0.25246 -1.98586 0.26749 0.82138 DataSet_01_226
SLC17A8 YBX1 shRNA Mammary_gland MDA 1.85961 0.895 0.13272 0.32191 DataSet_01_257
SLC17A8 POSTN shRNA Brain GSC272 7.72625 2.94977 0.1354 0.56122 DataSet_01_293
SLC17A8 TFAP4 siRNA Brain BE(2)-C 0.32175 -1.636 0.52257 0.54634 DataSet_01_295
SLC17A8 PTEN shRNA Lung HCC827 0.4924 -1.0221 0.12401 0.62288 DataSet_01_302
SLC17A8 PTEN shRNA Mammary_gland SKBR3 2.14074 1.09811 0.72079 0.91226 DataSet_01_303
SLC17A8 SOX9 siRNA Prostate VCaP 0.65854 -0.60266 0.56648 0.95187 DataSet_01_308
SLC17A8 SOX9 siRNA Prostate VCaP 0.65854 -0.60266 0.56648 0.95187 DataSet_01_309
SLC17A8 ARNT siRNA Upper_aerodigestive_tract HSC3 2.14186 1.09886 - - DataSet_01_315
SLC17A8 GATA3 siRNA Oral_cavity OEC-M1 2.27295 1.18456 0.0458 0.99787 DataSet_01_347
SLC17A8 GTF2B siRNA Cervix HeLa 0.66176 -0.59561 - - DataSet_01_362
SLC17A8 RBFOX2 shRNA Liver HepG2 3.25 1.70044 0.87198 0.9571 DataSet_02_101
SLC17A8 SAFB2 shRNA Liver HepG2 0.25926 -1.94753 0.02545 0.06832 DataSet_02_102
SLC17A8 HDGF shRNA Liver HepG2 1.75 0.80735 0.21794 0.3942 DataSet_02_104
SLC17A8 U2AF2 shRNA Liver HepG2 16 4 0.12471 0.25309 DataSet_02_105
SLC17A8 TAF15 shRNA Liver HepG2 7.33333 2.87447 0.00428 0.01902 DataSet_02_106
SLC17A8 GTF2F1 shRNA Liver HepG2 5 2.32193 0.46099 0.74411 DataSet_02_110
SLC17A8 RBM39 shRNA Liver HepG2 3.5 1.80735 0.05674 0.26513 DataSet_02_111
SLC17A8 BCLAF1 shRNA Liver HepG2 4.5 2.16993 0.00255 0.02828 DataSet_02_112
SLC17A8 U2AF2 shRNA Liver HepG2 3.75 1.90689 0.13335 0.26021 DataSet_02_113
SLC17A8 XRCC5 shRNA Liver HepG2 12 3.58496 0.0072 0.14276 DataSet_02_114
SLC17A8 PCBP1 shRNA Liver HepG2 13 3.70044 0.0037 0.02035 DataSet_02_115
SLC17A8 TARDBP shRNA Liver HepG2 1.81818 0.8625 0.06954 0.1304 DataSet_02_116
SLC17A8 SUB1 shRNA Liver HepG2 3 1.58496 0.04034 0.18641 DataSet_02_117
SLC17A8 RBM25 shRNA Liver HepG2 1.66667 0.73697 0.61169 0.69487 DataSet_02_119
SLC17A8 PTBP1 shRNA Liver HepG2 3.33333 1.73697 0.18114 0.22765 DataSet_02_120
SLC17A8 RBM34 shRNA Liver HepG2 11 3.45943 0.00352 0.39494 DataSet_02_121
SLC17A8 EWSR1 shRNA Liver HepG2 9 3.16993 0.0142 0.06974 DataSet_02_122
SLC17A8 PCBP2 shRNA Liver HepG2 26 4.70044 5e-04 0.04878 DataSet_02_123
SLC17A8 FUS shRNA Liver HepG2 26 4.70044 0.00109 0.05046 DataSet_02_124
SLC17A8 SRSF3 shRNA Liver HepG2 1.54545 0.62803 0.12363 0.26255 DataSet_02_127
SLC17A8 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.18182 -2.45943 0.00038 0.24862 DataSet_02_146
SLC17A8 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.06667 -3.90689 0.01549 0.37537 DataSet_02_154
SLC17A8 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.13333 -2.90689 0.01847 0.7666 DataSet_02_157
SLC17A8 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.26667 -1.90689 0.03562 0.62268 DataSet_02_159
SLC17A8 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.49461 0.65543 DataSet_02_160
SLC17A8 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.43026 1 DataSet_02_173
SLC17A8 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.20805 1 DataSet_02_176
SLC17A8 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.38789 1 DataSet_02_177
SLC17A8 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.07431 1 DataSet_02_191
SLC17A8 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.09982 1 DataSet_02_195
SLC17A8 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.18182 -2.45943 0.05764 1 DataSet_02_201
SLC17A8 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.44058 1 DataSet_02_202
SLC17A8 ZFX siRNA Mammary_gland MCF7 0.46154 -1.11548 0.69402 0.84415 DataSet_02_206
SLC17A8 GATA4 siRNA Stomach AGS 0.367091 -1.44579 0.216151137823154 0.832897327499662 DataSet_03_105
SLC17A8 GATA4 siRNA Stomach KatoIII 0.464787 -1.10536 0.145913360802709 0.902341177772022 DataSet_03_106
SLC17A8 GATA4 siRNA Stomach YCC3 3.77482 1.91641 0.240401202220543 0.755414338229189 DataSet_03_107
SLC17A8 GATA6 siRNA Stomach AGS 0.238439 -2.06831 0.0419864837390519 0.459499118939538 DataSet_03_108
SLC17A8 GATA6 siRNA Stomach KatoIII 0.645275 -0.632014 0.270520522894015 0.76367497930577 DataSet_03_109
SLC17A8 GATA6 siRNA Stomach YCC3 2.0426 1.03041 0.556567840950742 0.926187396894515 DataSet_03_110
SLC17A8 HNF4a siRNA Liver HepG2 8.08108 3.01455 0.07772469985006 0.684881738812213 DataSet_03_126
SLC17A8 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.136015 -2.87816 0.057532347381296 0.862763808134224 DataSet_03_134
SLC17A8 JARID1A siRNA Brain NB1691 2.78453 1.47743 0.00113810934917622 0.233226694323927 DataSet_03_136
SLC17A8 JUN siRNA Skin Ma-Mel-15 1.72641 0.787777 0.000354743655713694 0.463598556390881 DataSet_03_143
SLC17A8 KLF5 siRNA Stomach AGS 0.449039 -1.15509 0.210482704364424 0.685721085464299 DataSet_03_149
SLC17A8 KLF5 siRNA Stomach KatoIII 0.531132 -0.912857 0.234216595078903 0.680414855520123 DataSet_03_150
SLC17A8 KLF5 siRNA Stomach YCC3 3.31407 1.7286 0.254141419140411 0.620874597414891 DataSet_03_151
SLC17A8 MEF2D shRNA Liver HuH7 1.76575 0.820282 - - DataSet_03_162
SLC17A8 MEF2D siRNA Liver HuH7 0.642879 -0.637381 - - DataSet_03_163
SLC17A8 MYC siRNA Colon HT29 0.0698274 -3.84006 - - DataSet_03_177
SLC17A8 NR2F2 siRNA Uterus Primary eutopic stromal cells 1.89862 0.924948 0.129929514792254 0.99947668859931 DataSet_03_202
SLC17A8 PRRX1 CRISPR Neuroblastoma 691-MES 0.466652 -1.09958 0.162781144858374 0.89189998148014 DataSet_03_217
SLC17A8 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.333333 -1.58496 - - DataSet_03_246
SLC17A8 SP1 siRNA Ovary OVSAYO 0.644509 -0.633726 0.519179515884465 0.796836989637418 DataSet_03_251
SLC17A8 STAT6 siRNA Umbilical_vein HUVEC 0.219298 -2.18903 0.00356475990609485 0.426345735620147 DataSet_03_264
SLC17A8 TFAP2C siRNA Mammary_gland MCF7 2.1098 1.07711 0.107658634310185 0.457352445956728 DataSet_03_274
SLC17A8 TFE3 siRNA Kidney UOK257-2 5.94944 2.57275 - - DataSet_03_275
SLC17A8 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.214286 -2.22239 0.0697704573391237 0.181204716155929 DataSet_04_018
SLC17A8 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 5.2 2.37851 0.334790855529299 0.673605914952433 DataSet_04_022
SLC17A8 PAN2 CRISPR Liver HepG2 0.448276 -1.15754 0.451537554092179 0.610994917266244 DataSet_04_033
SLC17A8 SMAD4 CRISPR Liver HepG2 2.72727 1.44746 0.0166324166790216 0.107295996690916 DataSet_04_035
SLC17A8 DDX20 CRISPR Liver HepG2 2 1 0.168599283725762 0.313968935334952 DataSet_04_043
SLC17A8 CHCHD3 CRISPR Liver HepG2 8.5 3.08746 0.0192199006233763 0.462359872902174 DataSet_04_067
SLC17A8 PAN2 CRISPR Liver HepG2 2.72727 1.44746 0.0486726113676292 0.143595783061398 DataSet_04_066
SLC17A8 RIOK2 CRISPR Liver HepG2 2.625 1.39232 0.240433631512413 0.981517296308941 DataSet_04_070
SLC17A8 SEPT11 CRISPR Liver HepG2 0.291667 -1.77761 0.106221108333645 0.320595425445222 DataSet_04_068
SLC17A8 CALR shRNA Liver HepG2 0.1875 -2.41504 0.389743521040371 0.533333239318402 DataSet_04_053
SLC17A8 CCAR1 shRNA Liver HepG2 3.5 1.80735 0.697607958849472 0.818548499676706 DataSet_04_054
SLC17A8 CNOT7 shRNA Liver HepG2 2.66667 1.41504 0.738834344117595 0.816736051857822 DataSet_04_051
SLC17A8 DDX1 shRNA Liver HepG2 0.148148 -2.75489 0.102417992821099 0.300226348908855 DataSet_04_057
SLC17A8 NPM1 shRNA Liver HepG2 2 1 0.809932928041189 0.976251749713652 DataSet_04_058
SLC17A8 PRPF6 shRNA Liver HepG2 22 4.45943 0.14392648941795 0.328292647274531 DataSet_04_056
SLC17A8 YBX3 shRNA Liver HepG2 0.111111 -3.16992 0.0909597317733712 0.234044401849054 DataSet_02_98
SLC17A8 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.735879484010199 0.868317810866816 DataSet_04_048
SLC17A8 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.780714575637667 0.943719752683565 DataSet_02_75
SLC17A8 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.510883943215023 0.664692723003015 DataSet_04_060
SLC17A8 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.455873144908788 0.589876453494577 DataSet_04_059
SLC17A8 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0909091 -3.45943 0.380944144618435 0.635429229686251 DataSet_04_062
SLC17A8 AEBP1 siRNA Central_nervous_system U87MG 2.67477 1.41941 1.966733e-02 0.9431511 DataSet_03_338
SLC17A8 ESR1 siRNA Mammary_gland MCF7 3.62606 1.8584 5.445643e-02 0.1983015072 DataSet_03_352
SLC17A8 TET1 CRISPR Mammary_gland Hs578T 1.55673 0.638517 6.867516e-01 8.235306e-01 DataSet_03_355
SLC17A8 CREBBP CRISPR Brain U5-NPC 1.57692 0.657112 0.9736188549 0.9957609 DataSet_03_356
SLC17A8 DNMT3A knockout Embryo_kidney HEK293T 11.8897 3.57164 - - DataSet_03_369
SLC17A8 TPR shRNA Bone_marrow U2OS 1.58561 0.665035 8.761593e-01 9.746883e-01 DataSet_03_370
SLC17A8 GLI1 siRNA Skeletal_muscle RMS13 1.8594 0.894838 1.737022e-01 0.387106678 DataSet_03_375
SLC17A8 SMARCA2 shRNA Lung NCI-H1944 0.382353 -1.38702 6.409995e-02 4.132181e-01 DataSet_03_377
SLC17A8 NFKBIA shRNA Bone_marrow U2OS 0.00349977 -8.15853 5.249795e-01 0.87005461 DataSet_03_389
SLC17A8 YY1 knockdown Liver HepG2 0.35 -1.51457 3.427741e-01 5.113760e-01 DataSet_03_390
SLC17A8 KDM5A CRISPR Lung GLC16 2.10995 1.07721 3.080937e-02 0.086942019 DataSet_03_392
SLC17A8 ILF2 siRNA Stomach SGC-7901 0.625 -0.678072 0.6529717022 0.72959528 DataSet_03_393
SLC17A8 IKZF2 CRISPR Lymph CAR T Cell 0.522258 -0.937165 9.133433e-01 0.998006552 DataSet_03_397
SLC17A8 TLE4 CRISPR Lymph CAR T Cell 0.469697 -1.0902 9.133211e-01 0.98628617 DataSet_03_398
SLC17A8 SATB2 CRISPR Colon Colon organoid 1.54167 0.624491 6.252277e-01 0.99764242 DataSet_03_406
SLC17A8 E2F6 shRNA Liver HuH7 0.166284 -2.58828 - - DataSet_03_412
SLC17A8 MAEL CRISPR Liver Alexander cells 1.88889 0.917538 - - DataSet_03_423
SLC17A8 USP7 shRNA Skin xenograft cells 0.56 -0.836501 0.20533462 0.4348960 DataSet_03_431
SLC17A8 CBX2 siRNA Mammary_gland MCF7 0.523227 -0.934492 6.655641e-01 0.7963646695 DataSet_03_451
SLC17A8 SOX9 knockout Liver HuH7 1.70588 0.770518 2.635849e-01 4.338812e-01 DataSet_03_463
SLC17A8 PARP1 knockout Embryo_kidney HEK293a 9.125 3.18983 1.914100e-07 3.538241e-06 DataSet_03_464
SLC17A8 LIN28A siRNA Mammary_gland MCF7M 5.60167 2.48586 7.259316e-01 0.9484501 DataSet_03_469
SLC17A8 LIN28A siRNA Mammary_gland MCF7M 5.60167 2.48586 7.259316e-01 0.9484501 DataSet_03_470
SLC17A8 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.9219629 1 DataSet_04_071
SLC17A8 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 15 3.90689 0.2510967 0.6998235 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate FUS by the evidences of both expression and ChIP-seq/motif
Expression Atlas of SLC17A8
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines