Gene Overview
| Target Gene: | Slc14a1 |
| NCBI Official Symbol: | Slc14a1 |
| Entrez ID: | 108052 |
| Ensembl ID: | ENSMUSG00000059336 |
| Gene Full Name: | solute carrier family 14 (urea transporter), member 1 |
| Strand: | - |
| Gene Locus: | 18|18 E3 |
| External Links: |
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Slc14a1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Slc14a1
T(co)Fs
that Repress Slc14a1
The Intensity of the Gene Regulated by T(co)Fs:
Slc14a1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Slc14a1 | Adnp | knockout | Embryo | Whole embryonic body | 2.47573 | 1.30785 | 0.57850497275041 | 0.809603759547766 | DataSet_11_001 |
| Slc14a1 | Ahr | knockout | Lung | Lung | 2.06167 | 1.04381 | 0.142955762768503 | 0.999996968611848 | DataSet_11_003 |
| Slc14a1 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 0.0833213 | -3.58517 | 0.000107169582466306 | 0.00258687078377126 | DataSet_11_010 |
| Slc14a1 | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 1.68275 | 0.75082 | 0.00339040433646358 | 0.185787035501909 | DataSet_11_013 |
| Slc14a1 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.23383 | 1.15952 | 0.550063164016075 | 0.80366723618325 | DataSet_11_014 |
| Slc14a1 | Bcl6 | knockout | Bone_marrow | Myeloid cells | 1.51294 | 0.597356 | 0.0015792766601571 | 0.0203073634273517 | DataSet_11_015 |
| Slc14a1 | Bhlha9 | knockout | Limb | Whole limb bud | 0.383939 | -1.38105 | - | - | DataSet_11_016 |
| Slc14a1 | Cebpa | shRNA | Bone_marrow | Marrow progenitors | 0.382151 | -1.38779 | 0.0362092559886936 | 0.268590339178844 | DataSet_11_019 |
| Slc14a1 | Cebpb | knockout | Mammary_gland | Mammary epithlial cells (MECs) | 2.10672 | 1.075 | 0.0401522449267335 | 0.999788745984441 | DataSet_11_020 |
| Slc14a1 | Cebpb | shRNA | Mammary_gland | 4T1 mammary tumor cells | 4.68624 | 2.22843 | 0.249747106264066 | 0.999984070881864 | DataSet_11_022 |
| Slc14a1 | Dmrt1 | knockout | Testis | Juvenile testes | 1.55497 | 0.636882 | 0.181347253493459 | 0.932139260123802 | DataSet_11_026 |
| Slc14a1 | Dmrt1 | knockout | Testis | Juvenile testes | 1.69589 | 0.762042 | 0.0266461642107765 | 0.778434098416569 | DataSet_11_028 |
| Slc14a1 | Dmrt1 | knockout | Testis | Testes | 2.26326 | 1.1784 | 0.00625457203526015 | 0.107123103702172 | DataSet_11_029 |
| Slc14a1 | Dmrt1 | knockout | Ovary | Ovary | 0.559717 | -0.837231 | 0.00756476325833251 | 0.102863142541232 | DataSet_11_030 |
| Slc14a1 | Dmrt1 | knockout | Ovary | Ovary | 0.559717 | -0.837231 | 0.00756476325833251 | 0.102863142541232 | DataSet_11_031 |
| Slc14a1 | Dmrt1 | knockout | Testis | Testes | 2.26326 | 1.1784 | 0.00625457203526015 | 0.107123103702172 | DataSet_11_032 |
| Slc14a1 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.58179 | 0.661556 | 0.124625547127417 | 0.410313305107024 | DataSet_11_035 |
| Slc14a1 | Foxp1 | knockout | Eye | Lens | 0.257732 | -1.95606 | - | - | DataSet_11_044 |
| Slc14a1 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.545725 | -0.873755 | - | - | DataSet_11_047 |
| Slc14a1 | Gata4 | knockout | Intestine | Jejunum | 0.602004 | -0.732155 | 0.0607142919413082 | 0.530647524910762 | DataSet_11_049 |
| Slc14a1 | Gfi1 | knockout | Macrophage_cells | RAW264.7 | 1.69052 | 0.757465 | 0.00186060388654431 | 0.00794506791950524 | DataSet_11_052 |
| Slc14a1 | Gfi1 | knockout | Cord_Blood | T-cells | 0.561038 | -0.833829 | 0.0827113302919932 | 0.455418997758998 | DataSet_11_053 |
| Slc14a1 | Hnf1a | knockout | Intestine | Jejunum | 0.641956 | -0.639453 | 0.0250213332302648 | 0.188706345889343 | DataSet_11_056 |
| Slc14a1 | Hsf4 | knockout | Eye | Lens | 0.455019 | -1.136 | 0.369019023217459 | 0.987999303842427 | DataSet_11_058 |
| Slc14a1 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.507615 | -0.978195 | 0.0315624793920135 | 0.179710686351154 | DataSet_11_065 |
| Slc14a1 | Lhx8 | knockout | Ovary | Ovary | 18.2172 | 4.18723 | 1.1173579102392e-05 | 0.0100703454019506 | DataSet_11_070 |
| Slc14a1 | Lmx1b | knockout | Kidney | Kidney | 0.246526 | -2.02019 | 0.000604421537098139 | 0.0466440734772021 | DataSet_11_072 |
| Slc14a1 | Mafg | knockout | Embryo | Whole embryo | 0.427844 | -1.22484 | 0.238396629337946 | 1 | DataSet_11_073 |
| Slc14a1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.389313 | -1.361 | - | - | DataSet_11_074 |
| Slc14a1 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 3.9358 | 1.97666 | 4.65970665250608e-07 | 3.3212019133893e-05 | DataSet_11_076 |
| Slc14a1 | Neurod1 | knockout | Eye | Retina | 2.54832 | 1.34955 | 3.94717986948024e-07 | 9.09649529698774e-05 | DataSet_11_088 |
| Slc14a1 | Nfil3 | knockout | Bone_marrow | Prepro NK cells | 1.66636 | 0.736703 | 0.280778989646573 | 0.59802165652737 | DataSet_11_090 |
| Slc14a1 | Nhlh2 | knockout | Eye | Retina | 0.641509 | -0.640458 | 0.237986739551598 | 0.523726874680013 | DataSet_11_092 |
| Slc14a1 | Pbx1 | knockout | Bone_marrow | BM cells | 0.285852 | -1.80666 | 0.0490984026192882 | 0.495061829766129 | DataSet_11_102 |
| Slc14a1 | Pitx2 | knockout | Eye | Cornea | 2.45536 | 1.29594 | 0.151730211692467 | 0.528692320101133 | DataSet_11_103 |
| Slc14a1 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 2.08844 | 1.06243 | 0.149087409178673 | 0.801717151104739 | DataSet_11_105 |
| Slc14a1 | Prdm2 | shRNA | Muscle | C2C12 | 0.175228 | -2.5127 | 0.00855796824151164 | 0.602932787533663 | DataSet_11_108 |
| Slc14a1 | Rest | knockout | Brain | Brain | 3.61403 | 1.85361 | 0.00879479767182793 | 0.782887976443704 | DataSet_11_113 |
| Slc14a1 | Runx1 | knockout | Embryo | Embryo | 0.593173 | -0.753474 | 0.142761815062947 | 0.999961610631375 | DataSet_11_114 |
| Slc14a1 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 3.15112 | 1.65586 | 0.235335356826718 | 0.999784944667092 | DataSet_11_117 |
| Slc14a1 | Runx2 | knockout | Humeri | Embryonic humeri | 0.513344 | -0.962002 | 0.0220223952360733 | 0.326644353645419 | DataSet_11_120 |
| Slc14a1 | Sall1 | knockout | Kidney | Kidney | 2.51487 | 1.33048 | 0.239131978419279 | 0.945620084902242 | DataSet_11_122 |
| Slc14a1 | Smad4 | siRNA | Brain | bEnd3 | 0.0066202 | -7.23891 | - | - | DataSet_11_127 |
| Slc14a1 | Smad4 | knockout | Aorta | Aortic arteries | 3.49113 | 1.80369 | 0.0407793114604448 | 0.309478877990356 | DataSet_11_128 |
| Slc14a1 | Snai1 | knockout | Embryo | Teratoma | 1.92881 | 0.947711 | - | - | DataSet_11_130 |
| Slc14a1 | Sohlh1 | knockout | Ovary | Ovary | 0.401612 | -1.31613 | 7.57619343193536e-08 | 8.94118513621719e-06 | DataSet_11_134 |
| Slc14a1 | Sohlh2 | knockout | Ovary | Ovary | 0.556148 | -0.846458 | 6.29428194214656e-07 | 2.99149277734554e-05 | DataSet_11_135 |
| Slc14a1 | Sox11 | knockout | Eye | Retina | 0.553398 | -0.853611 | - | - | DataSet_11_137 |
| Slc14a1 | Spdef | knockout | Colon | Colon | 0.319621 | -1.64557 | 0.0530951813696342 | 0.997507742354799 | DataSet_11_146 |
| Slc14a1 | Stat3 | knockout | Lung | Lung typeII cells | 5.84307 | 2.54673 | 0.00586758558191986 | 0.53023486969546 | DataSet_11_151 |
| Slc14a1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 3.32934 | 1.73524 | 0.00282668977571941 | 0.0191034123943292 | DataSet_11_153 |
| Slc14a1 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.365259 | -1.45301 | - | - | DataSet_11_189 |
| Slc14a1 | Mapk9 | knockout | Knee | Mouse total knee | 0.325631 | -1.61869 | 5.674322e-02 | 0.222681046 | DataSet_11_237 |
| Slc14a1 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.646914 | -0.628355 | 1.280912e-01 | 2.842889e-01 | DataSet_11_192 |
| Slc14a1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.611765 | -0.708951 | - | - | DataSet_11_196 |
| Slc14a1 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 0.457492 | -1.12818 | - | - | DataSet_11_220 |
| Slc14a1 | Ezh2 | knockdown | Brain | Brain | 0.491807 | -1.02383 | 6.668849e-04 | 0.0219467702 | DataSet_11_221 |
| Slc14a1 | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 0.400366 | -1.32061 | 3.463893e-02 | 0.309484540 | DataSet_11_199 |
| Slc14a1 | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 1.9207 | 0.941633 | - | - | DataSet_11_222 |
| Slc14a1 | Crebbp | knockout | Spleen | Germinal center B cells | 0.588538 | -0.764794 | 7.658427e-02 | 0.665503550 | DataSet_11_227 |
| Slc14a1 | Dnmt3a | siRNA | Embryo | iPSC | 0.09004 | -3.47329 | - | - | DataSet_11_241 |
| Slc14a1 | Dnmt3b | siRNA | Embryo | iPSC | 0.500499 | -0.99856 | - | - | DataSet_11_242 |
| Slc14a1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.286221 | -1.8048 | 5.069397e-03 | 0.0661240834 | DataSet_11_245 |
| Slc14a1 | Fubp1 | shRNA | Brain | brain neural progenitors | 1.73742 | 0.796948 | 0.3778121326 | 1 | DataSet_11_246 |
| Slc14a1 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 0.296893 | -1.75198 | 3.348136e-04 | 2.147093e-03 | DataSet_11_249 |
| Slc14a1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.28972 | -1.78727 | 3.479752e-03 | 2.187216e-02 | DataSet_11_250 |
| Slc14a1 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 6.52011 | 2.7049 | 1.345787e-01 | 0.296380187 | DataSet_11_252 |
| Slc14a1 | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 3.89068 | 1.96002 | 8.229756e-02 | 0.350805224 | DataSet_11_253 |
| Slc14a1 | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 1.66754 | 0.737718 | 8.687447e-03 | 0.1327666 | DataSet_11_254 |
| Slc14a1 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 0.438145 | -1.19052 | 0.3484302989 | 0.6871281 | DataSet_11_256 |
| Slc14a1 | Eed | knockout | Brain | Forebrain | 2.47321 | 1.30639 | 2.805082e-02 | 4.240792e-01 | DataSet_11_258 |
| Slc14a1 | Eed | knockout | Brain | hindbrain | 2.64087 | 1.40101 | 5.179143e-02 | 7.804197e-01 | DataSet_11_259 |
| Slc14a1 | Eed | knockout | Brain | midbrain | 3.84108 | 1.94151 | 6.059169e-03 | 2.649125e-01 | DataSet_11_260 |
| Slc14a1 | Eed | knockout | Spinal_cord | spinal cord | 1.68505 | 0.752794 | 2.240658e-01 | 9.999790e-01 | DataSet_11_261 |
| Slc14a1 | Ctnnb1 | knockout | Embryo | MGE cells | 1.95208 | 0.965015 | 1.080594e-01 | 0.367350359 | DataSet_11_266 |
| Slc14a1 | Dux | knockout | Embryo | Embryo | 1.97811 | 0.98412 | 4.710422e-01 | 6.471454e-01 | DataSet_11_269 |
| Slc14a1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.000000418583 | -21.188 | 3.541541e-01 | 0.81420760 | DataSet_11_272 |
| Slc14a1 | Dux | knockout | Embryo | Embryo | 1.97811 | 0.98412 | 4.710432e-01 | 6.471704e-01 | DataSet_11_273 |
| Slc14a1 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 0.285714 | -1.80736 | 9.237587e-02 | 3.578235e-01 | DataSet_11_276 |
| Slc14a1 | Gsk3b | CRISPR | Neuron | mPFC D2 neurons | 0.380895 | -1.39253 | 1.484239e-01 | 0.85266614 | DataSet_11_277 |
| Slc14a1 | Ssrp1 | CRISPR | Embryo | ES cells | 0.5 | -1 | 7.472217e-01 | 0.9363812 | DataSet_11_278 |
| Slc14a1 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 6.15495 | 2.62175 | 2.595300e-03 | 0.5395938 | DataSet_11_284 |
| Slc14a1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.88889 | 0.917538 | - | - | DataSet_11_285 |
| Slc14a1 | Pdx1 | CRISPR | Liver | Liver | 0.655172 | -0.610053 | 1.728885e-01 | 0.458690924 | DataSet_11_286 |
| Slc14a1 | Setd1a | shRNA | Eye | Retina | 1.59149 | 0.670376 | 7.190291e-01 | 0.8614791282 | DataSet_11_293 |
| Slc14a1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 0.43379 | -1.20493 | 5.497353e-01 | 8.203864e-01 | DataSet_11_297 |
| Slc14a1 | Phf8 | knockout | prostate | Prostate | 0.0338753 | -4.88362 | 0.0217379781 | 0.1802828 | DataSet_11_298 |
| Slc14a1 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.532764 | -0.908431 | 5.963260e-01 | 0.9999903 | DataSet_11_299 |
| Slc14a1 | Dnmt1 | knockout | Skin | Keratinocytes | 3.98864 | 1.9959 | 3.469128e-02 | 0.2584339451 | DataSet_11_303 |
| Slc14a1 | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 1.66667 | 0.736966 | 5.682392e-01 | 0.96373360 | DataSet_11_309 |
| Slc14a1 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 3.85727 | 1.94758 | 5.160537e-01 | 0.85643211 | DataSet_11_310 |
| Slc14a1 | Suz12 | knockout | Lung | Alveolar macrophage | 0.543689 | -0.879146 | 9.252482e-01 | 0.9822416571 | DataSet_11_311 |
| Slc14a1 | Suz12 | knockout | Lung | Alveolar macrophage | 13.2 | 3.72247 | 2.143106e-02 | 8.809497e-02 | DataSet_11_312 |
| Slc14a1 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 0.0750138 | -3.7367 | - | - | DataSet_11_313 |
| Slc14a1 | Satb2 | knockout | Colon | Intestine epithelium | 0.154839 | -2.69116 | 1.003567e-01 | 0.4478154605 | DataSet_11_316 |
| Slc14a1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 12.5 | 3.64386 | 1.781741e-04 | 0.0226974915 | DataSet_11_317 |
| Slc14a1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.287671 | -1.79751 | 7.358353e-02 | 3.975237e-01 | DataSet_11_319 |
| Slc14a1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 1.72881 | 0.789782 | 3.684664e-02 | 1.647743e-01 | DataSet_11_320 |
| Slc14a1 | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.00653595 | -7.25739 | 1.007902e-01 | 0.8600602 | DataSet_11_321 |
| Slc14a1 | Padi2 | knockout | Testis | Testis | 0.625 | -0.678072 | 3.314153e-01 | 0.9800332 | DataSet_11_324 |
| Slc14a1 | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.333333 | -1.58496 | 2.414468e-01 | 0.9832045 | DataSet_11_325 |
| Slc14a1 | Snai1 | knockdown | Heart | Heart | 0.63755 | -0.649389 | 7.034795e-03 | 0.05984377 | DataSet_11_326 |
| Slc14a1 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 3.21311 | 1.68397 | 1.205014e-01 | 0.9609895 | DataSet_11_327 |
| Slc14a1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 6.73697 | 2.7521 | 2.262843e-03 | 4.045766e-02 | DataSet_11_332 |
| Slc14a1 | Ezh2 | knockout | Eye | Retina | 0.0420168 | -4.57289 | 3.704430e-07 | 6.446110e-05 | DataSet_11_333 |
| Slc14a1 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 2.6 | 1.37851 | 5.693252e-02 | 0.55135465 | DataSet_11_338 |
| Slc14a1 | Gtf2ird1 | knockout | Lip | Lip | 3.93491 | 1.97633 | 2.379264e-04 | 1.950996e-02 | DataSet_11_339 |
| Slc14a1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 1.8 | 0.847997 | 7.695766e-02 | 0.143388959 | DataSet_11_340 |
| Slc14a1 | Hnrnpk | siRNA | Embryo | ES cells | 3.37833 | 1.75631 | 8.499973e-01 | 0.912232766 | DataSet_11_342 |
| Slc14a1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 6.05945 | 2.59919 | 9.794609e-02 | 3.266607e-01 | DataSet_11_344 |
| Slc14a1 | Dux | shRNA | Embryo | ES cells | 0.375 | -1.41504 | 1.154811e-01 | 6.059606e-01 | DataSet_11_345 |
| Slc14a1 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 1.66667 | 0.736966 | 5.682392e-01 | 0.96373360 | DataSet_11_347 |
Regulation Region
Expression Atlas of Slc14a1