Gene Overview
Target Gene: TFPI2
NCBI Official Symbol: TFPI2
Entrez ID: 7980
Ensembl ID: ENSG00000105825
Gene Full Name: tissue factor pathway inhibitor 2
Strand: -
Gene Locus: 7q21.3
External Links:

TFPI2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate TFPI2   
T(co)Fs that Repress TFPI2
The Intensity of the Gene Regulated by T(co)Fs:
TFPI2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
TFPI2 HNF1B shRNA Ovary RMG2 0.15796 -2.66236 5.90592e-12 6.01281e-10 DataSet_01_103
TFPI2 HOXA1 siRNA Lung_fibroblast IMR-90 2.65202 1.40709 0.00128 0.03725 DataSet_01_110
TFPI2 ID1 siRNA Lung A549 1.66744 0.73764 0.04534 0.23216 DataSet_01_117
TFPI2 ZIC2 siRNA Pancreas PANC1 1.57511 0.65545 - - DataSet_01_121
TFPI2 FOXM1 siRNA Central_nervous_system U87 7.16399 2.84076 - - DataSet_01_122
TFPI2 SPDEF shRNA Mammary_gland MCF7 1.60072 0.67872 0.00417 0.10365 DataSet_01_135
TFPI2 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.08501 1.06005 0.10443 0.8809 DataSet_01_137
TFPI2 POLR3A siRNA Mammary_gland MCF7 3 1.58496 - - DataSet_01_139
TFPI2 REST siRNA Adrenal_gland H295R/TR 1.80034 0.84827 0.00013 0.02133 DataSet_01_145
TFPI2 SF1 siRNA Adrenal_gland H295R/TR 2.44677 1.29088 1.40025e-07 4.43143e-05 DataSet_01_146
TFPI2 EHF siRNA Corneal_epithelial Corneal epithelial cells 2.02535 1.01817 4.2042e-07 0.00045 DataSet_01_147
TFPI2 LIN28B siRNA Embryo_kidney HEK293 2.15672 1.10884 4.79037e-05 0.00928 DataSet_01_153
TFPI2 ELK1 siRNA Peripheral_blood CD4+ T cells 0.58073 -0.78406 0.09364 0.2333 DataSet_01_162
TFPI2 GATA3 siRNA Peripheral_blood CD4+ T cells 0.60694 -0.72036 0.12493 0.45225 DataSet_01_163
TFPI2 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.53433 -0.9042 0.05398 0.24433 DataSet_01_166
TFPI2 NFKB1 siRNA Peripheral_blood CD4+ T cells 0.57861 -0.78934 0.09424 0.67337 DataSet_01_167
TFPI2 HOXB7 siRNA Pancreas MIA PaCa-2 0.50169 -0.99512 0.27611 0.71016 DataSet_01_169
TFPI2 FOSL1 siRNA Mammary_gland BT549 1.6094 0.68653 0.00021 0.01374 DataSet_01_171
TFPI2 JUN siRNA Mammary_gland BT549 1.63887 0.7127 0.00191 0.08691 DataSet_01_172
TFPI2 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.83279 1.50223 0.00684 0.07122 DataSet_01_185
TFPI2 CREB1 shRNA Parotid_gland H3118 MEC 0.33609 -1.57309 0.0151 0.21166 DataSet_01_194
TFPI2 TP63 siRNA Head_and_neck SCC-012 0.56806 -0.81587 - - DataSet_01_201
TFPI2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.43903 -1.18762 - - DataSet_01_210
TFPI2 EGR3 shRNA Prostate M12 0.1356 -2.88262 0.00799 0.10586 DataSet_01_212
TFPI2 LIN28A siRNA Embryo H9 4.31031 2.10779 1.69886e-05 0.00112 DataSet_01_215
TFPI2 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 8.89984 3.15378 2.6763e-07 0.00147 DataSet_01_217
TFPI2 ATM shRNA Mammary_gland MCF10A 4.8432 2.27596 1.41616e-07 5.20399e-06 DataSet_01_219
TFPI2 KLF2 shRNA Bone_marrow RPMI8226 2.43105 1.28158 0.44541 0.88846 DataSet_01_226
TFPI2 ESR2 siRNA Mammary_gland BT549 1.92297 0.94333 5.76495e-08 1.34204e-05 DataSet_01_229
TFPI2 EGR2 siRNA Muscle A673 1.62729 0.70247 0.37743 0.8374 DataSet_01_242
TFPI2 EGR2 siRNA Neuroepithelium SK-N-MC 1.78573 0.83652 0.27708 0.83418 DataSet_01_243
TFPI2 TWIST1 shRNA Stomach CAF14 1.89766 0.92422 0.13182 0.99996 DataSet_01_252
TFPI2 TWIST1 shRNA Stomach CAF32 25.4092 4.66728 7.63086e-06 0.01138 DataSet_01_253
TFPI2 TWIST1 shRNA Stomach CAF 6.94393 2.79575 0.08298 0.57298 DataSet_01_254
TFPI2 YBX1 shRNA Mammary_gland MDA 0.36878 -1.43915 6.82912e-10 9.77583e-08 DataSet_01_255
TFPI2 SOX4 shRNA Mammary_gland MDA-MB-231 1.73606 0.79581 0.00481 0.08467 DataSet_01_260
TFPI2 FOXO3 siRNA Pancreas PANC1 0.53986 -0.88935 - - DataSet_01_267
TFPI2 SIX4 siRNA Ovary PEO1 0.34526 -1.53426 0.00044 0.00846 DataSet_01_269
TFPI2 SALL4 shRNA Lung H661 0.6633 -0.59227 0.18414 0.55362 DataSet_01_277
TFPI2 STAT5 shRNA Prostate CWR22Pc 2.61289 1.38565 0.00156 0.01922 DataSet_01_279
TFPI2 MSX1 siRNA Tooth Dental Pulp Cells 0.33566 -1.57491 0.00033 0.00229 DataSet_01_281
TFPI2 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.23549 -2.08623 2.99507e-05 0.00076 DataSet_01_283
TFPI2 ZIC5 siRNA Skin SK-MEL-28 0.49718 -1.00816 - - DataSet_01_285
TFPI2 GRHL2 shRNA Ovary OVCA429 1.55051 0.63274 0.22704 0.93924 DataSet_01_289
TFPI2 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.50015 0.58511 0.1529 0.892 DataSet_01_290
TFPI2 JUN siRNA Mammary_gland BT549 1.71715 0.78002 0.31832 0.57171 DataSet_01_291
TFPI2 POSTN shRNA Brain GSC272 0.37606 -1.41098 0.05326 0.53645 DataSet_01_293
TFPI2 TFAP4 siRNA Brain BE(2)-C 0.58759 -0.76713 0.66807 0.67523 DataSet_01_295
TFPI2 PTEN shRNA Skin A431 2.789 1.47975 0.17295 0.36157 DataSet_01_301
TFPI2 PTEN shRNA Mammary_gland SKBR3 0.54287 -0.88132 0.27602 0.71413 DataSet_01_303
TFPI2 ETV5 siRNA Soft_tissue hADSC 0.63483 -0.65556 0.17373 0.43001 DataSet_01_304
TFPI2 NR2E1 shRNA Neuroepithelium PBT003 0.63009 -0.66636 0.03091 0.45072 DataSet_01_306
TFPI2 RUNX1 shRNA Embryo H9 0.60527 -0.72435 0.29257 0.51969 DataSet_01_314
TFPI2 ELK3 shRNA Mammary_gland MDA-MB-231 0.17087 -2.54905 3.62068e-06 6.95201e-05 DataSet_01_318
TFPI2 ZNF25 siRNA Bone_marrow hMSC-TERT4 0.5262 -0.92632 0.07812 0.56382 DataSet_01_319
TFPI2 TP63 shRNA Immortalized_keratinocyte HaCaT 2.87662 1.52437 5.17709e-11 1.16659e-07 DataSet_01_325
TFPI2 TP63 shRNA Head_and_neck FaDU 2.14406 1.10034 5.59886e-07 9.61245e-05 DataSet_01_327
TFPI2 TP63 shRNA Immortalized_keratinocyte HaCaT 2.87662 1.52437 5.17709e-11 1.16659e-07 DataSet_01_328
TFPI2 TP63 shRNA Head_and_neck FaDU 2.14406 1.10034 5.59886e-07 9.61245e-05 DataSet_01_330
TFPI2 HOXC6 siRNA Prostate LNCaP 2.13924 1.0971 0.01222 0.99927 DataSet_01_333
TFPI2 GRHL3 siRNA Skin NHEK 1.98735 0.99085 0.01616 0.35311 DataSet_01_336
TFPI2 REST siRNA Skin NHEK 0.6154 -0.7004 0.00232 0.04935 DataSet_01_337
TFPI2 REST siRNA Skin NHEK 0.65101 -0.61924 0.00611 0.56522 DataSet_01_338
TFPI2 KLF7 siRNA Embryo HCE 0.08558 -3.54655 0.14572 0.6419 DataSet_01_340
TFPI2 KLF4 siRNA Embryo HCE 0.64933 -0.62298 0.01272 0.40408 DataSet_01_341
TFPI2 KLF7 siRNA Embryo HCE 0.42528 -1.23351 0.00294 0.99985 DataSet_01_342
TFPI2 ARID1A shRNA Uterus iEEC16 1.5561 0.63793 - - DataSet_01_345
TFPI2 GATA3 siRNA Oral_cavity OEC-M1 0.56795 -0.81616 0.21853 0.99787 DataSet_01_347
TFPI2 SOX2 shRNA Neuroepithelium HF2303 0.64498 -0.63268 0.16844 1 DataSet_01_349
TFPI2 ZNF24 siRNA Embryo_kidney HEK293 0.52413 -0.932 - - DataSet_01_353
TFPI2 ETV4 shRNA Prostate PC3 0.31324 -1.67467 - - DataSet_01_356
TFPI2 GTF2B siRNA Cervix HeLa 2.58226 1.36863 - - DataSet_01_362
TFPI2 RBM17 shRNA Liver HepG2 0.35294 -1.5025 0.12384 0.39007 DataSet_02_100
TFPI2 SAFB2 shRNA Liver HepG2 0.53571 -0.90046 0.7404 0.80736 DataSet_02_102
TFPI2 FIP1L1 shRNA Liver HepG2 49.3333 5.62449 0.00475 0.02876 DataSet_02_103
TFPI2 SSB shRNA Liver HepG2 0.14634 -2.77259 0.00174 0.00967 DataSet_02_107
TFPI2 ZNF622 shRNA Liver HepG2 2 1 0.18278 0.25103 DataSet_02_108
TFPI2 BCLAF1 shRNA Liver HepG2 0.62162 -0.68589 0.43812 0.55536 DataSet_02_112
TFPI2 TARDBP shRNA Liver HepG2 0.58065 -0.78427 0.1761 0.26155 DataSet_02_116
TFPI2 CEBPZ shRNA Liver HepG2 3.33333 1.73697 0.02075 1 DataSet_02_118
TFPI2 EWSR1 shRNA Liver HepG2 0.54762 -0.86876 0.13278 0.24232 DataSet_02_122
TFPI2 HNRNPLL shRNA Liver HepG2 0.20968 -2.25376 0.00257 0.01728 DataSet_02_125
TFPI2 SNRNP70 shRNA Liver HepG2 0.35484 -1.49476 0.00064 0.03074 DataSet_02_126
TFPI2 PRPF4 shRNA Liver HepG2 0.125 -3 0.07329 0.16168 DataSet_02_128
TFPI2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.50249 0.73035 DataSet_02_129
TFPI2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.88889 2.28951 0.2011 0.30284 DataSet_02_131
TFPI2 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.83333 1.5025 0.05514 0.18518 DataSet_02_132
TFPI2 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.09976 0.33177 DataSet_02_133
TFPI2 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 2.11111 1.078 0.76548 0.84659 DataSet_02_134
TFPI2 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.11111 1.63743 0.47936 0.62681 DataSet_02_135
TFPI2 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 6.11111 2.61143 0.21377 0.43125 DataSet_02_136
TFPI2 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56863 -0.81444 0.17182 0.45348 DataSet_02_138
TFPI2 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.69752 0.8648 DataSet_02_139
TFPI2 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 2.11111 1.078 0.63677 0.7841 DataSet_02_141
TFPI2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 5.16667 2.36923 0.78292 0.83447 DataSet_02_143
TFPI2 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.54167 -0.88452 0.64624 0.75726 DataSet_02_147
TFPI2 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.21429 -2.22239 0.0236 0.2724 DataSet_02_148
TFPI2 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.11816 0.3165 DataSet_02_151
TFPI2 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.1875 1.12928 0.00374 0.0795 DataSet_02_158
TFPI2 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.45 -1.152 0.48428 0.86219 DataSet_02_159
TFPI2 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2.72414 1.4458 0.02702 0.15331 DataSet_02_160
TFPI2 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.80952 2.26589 0.04217 0.54119 DataSet_02_162
TFPI2 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 0.28571 -1.80735 0.09822 0.29573 DataSet_02_164
TFPI2 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.26667 2.09311 0.02826 0.17223 DataSet_02_165
TFPI2 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56667 -0.81943 0.35004 0.56468 DataSet_02_166
TFPI2 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 16 4 0.04041 0.23874 DataSet_02_167
TFPI2 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 4.88889 2.28951 0.01615 0.08404 DataSet_02_168
TFPI2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.48659 0.5842 DataSet_02_169
TFPI2 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 4.43333 2.14839 0.04711 0.1317 DataSet_02_170
TFPI2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.13333 -2.90689 0.1099 0.30629 DataSet_02_171
TFPI2 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.41379 -1.27302 0.09838 1 DataSet_02_174
TFPI2 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.36667 -1.44746 0.68847 1 DataSet_02_175
TFPI2 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 1.77778 0.83007 0.26409 1 DataSet_02_176
TFPI2 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.54167 1.34577 0.11488 1 DataSet_02_178
TFPI2 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.26829 -1.89812 0.00343 1 DataSet_02_179
TFPI2 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.26923 -1.89308 0.12303 1 DataSet_02_182
TFPI2 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 3.66667 1.87447 0.08157 1 DataSet_02_183
TFPI2 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.30233 -1.72583 0.11414 1 DataSet_02_184
TFPI2 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.23319 1 DataSet_02_185
TFPI2 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6087 -0.71621 0.59865 1 DataSet_02_186
TFPI2 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.11111 2.03953 0.20162 1 DataSet_02_188
TFPI2 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 2.93333 1.55254 0.19122 1 DataSet_02_190
TFPI2 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.03333 -4.90689 0.01759 1 DataSet_02_191
TFPI2 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.92087 1 DataSet_02_192
TFPI2 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.47826 -1.06413 0.52541 1 DataSet_02_193
TFPI2 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.14236 1 DataSet_02_194
TFPI2 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.04646 0.15656 DataSet_02_196
TFPI2 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.25758 -1.95693 0.31927 1 DataSet_02_201
TFPI2 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 1.77778 0.83007 0.61461 1 DataSet_02_205
TFPI2 AR siRNA Prostate LNCaP 1.94444 0.959358 0.264916648484863 1 DataSet_03_005
TFPI2 ASCL1 siRNA Lung DMS79 0.263333 -1.92504 0.148277909806263 0.810683683797745 DataSet_03_016
TFPI2 ATF4 siRNA Skin A375 1.57126 0.651922 0.380564746326291 0.775512819201899 DataSet_03_018
TFPI2 ATOH8 siRNA Umbilical_vein HUVEC 1.82794 0.870222 0.238886437486764 0.947329177896605 DataSet_03_019
TFPI2 BCL6 siRNA Mammary_gland MCF7 2.4184 1.27405 0.000678078936833215 0.458713429957964 DataSet_03_024
TFPI2 BCL6 siRNA Lymph Pfeiffer DLBCL 0.428658 -1.2221 0.00153997881883442 0.185682603485989 DataSet_03_026
TFPI2 BCL6 siRNA Central_nervous_system U87 0.526672 -0.925022 0.000726442628884981 0.0499073278545258 DataSet_03_027
TFPI2 E2F7 siRNA Upper_aerodigestive_tract SCC25 0.55982 -0.836965 5.91154360211972e-06 0.000128479528036019 DataSet_03_063
TFPI2 ETS1 siRNA Fibroblasts WI38 0.563087 -0.828571 0.252574997763146 0.486237616952925 DataSet_03_073
TFPI2 ETS1 siRNA Fibroblasts WI38 0.584389 -0.775 0.320745430175085 0.545013409402732 DataSet_03_074
TFPI2 FOXM1 siRNA Oesophagus TE1 0.502063 -0.99406 0.000418138004309949 0.948263470156127 DataSet_03_093
TFPI2 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.102549 -3.28562 - - DataSet_03_096
TFPI2 GATA2 siRNA Lymph Lymphatic endothelial cells 2.47005 1.30454 6.82132443122223e-05 0.00060121665044341 DataSet_03_101
TFPI2 GATA4 siRNA Stomach AGS 0.648304 -0.625257 0.0519791978120967 0.662225247700509 DataSet_03_105
TFPI2 GATA6 siRNA Stomach KatoIII 2.52084 1.33391 0.0651575924361035 0.575518499080291 DataSet_03_109
TFPI2 GATA6 siRNA Stomach YCC3 1.68139 0.74965 0.450953186847074 0.893720671571917 DataSet_03_110
TFPI2 GFP siRNA Mammary_gland BT-20 cells 0.65812 -0.603578 0.00220719158670558 0.254090275504419 DataSet_03_111
TFPI2 GRHL3 siRNA Skin Primary neonatal keratinocytes 3.65092 1.86826 0.0505196177122855 0.287185543907375 DataSet_03_113
TFPI2 HNF4a siRNA Liver HepG2 2.99024 1.58026 0.204465324497804 0.802359018195136 DataSet_03_126
TFPI2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.415715 -1.26633 0.0484081293269343 0.82024885803972 DataSet_03_134
TFPI2 MEF2D shRNA Liver HuH7 1.61857 0.694717 - - DataSet_03_162
TFPI2 MEF2D siRNA Liver HuH7 0.585764 -0.771609 - - DataSet_03_163
TFPI2 MITF siRNA Skin MZ7 1.77896 0.831034 2.07067101076005e-05 0.000224921290066716 DataSet_03_165
TFPI2 MITF siRNA Skin Ma-Mel-15 1.74631 0.804313 0.243261502683079 0.645949183590001 DataSet_03_167
TFPI2 MYB siRNA Prostate PC-3M 0.499884 -1.00033 3.20421414337056e-06 0.000248592416567059 DataSet_03_173
TFPI2 NFAT5 siRNA Synovial Primary fibroblast-like synoviocytes 2.14733 1.10254 0.0132085711592429 0.175768343354782 DataSet_03_194
TFPI2 NFAT5 siRNA Umbilical_vein HUVEC 1.53718 0.620287 0.00998112729491043 0.152887575468717 DataSet_03_195
TFPI2 PAX3 siRNA Mammary_gland MCF7 0.643422 -0.636162 0.0682255577179387 0.919978041032696 DataSet_03_206
TFPI2 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.37233 1.24631 2.20205042173692e-05 0.000536997768949471 DataSet_03_211
TFPI2 PRRX1 CRISPR Neuroblastoma 691-MES 0.512858 -0.963368 0.179141306220289 0.89189998148014 DataSet_03_217
TFPI2 RELB siRNA Immortalized_keratinocyte HaCaT 14.6226 3.87013 5.7942596100758e-09 4.20755646386993e-07 DataSet_03_227
TFPI2 SOX11 siRNA Lung_fibroblast NHLF 0.595847 -0.746986 0.030891043127614 0.272267180081438 DataSet_03_238
TFPI2 SOX2 siRNA Embryo 2102Ep 0.530807 -0.91374 0.000147196916700718 0.00471754148689023 DataSet_03_242
TFPI2 SOX2 siRNA Embryo NTera-2 0.482345 -1.05186 3.84013674482353e-07 0.000151529192468198 DataSet_03_243
TFPI2 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.06667 1.04731 - - DataSet_03_246
TFPI2 SOX9 knockdown Liver HepG2 2.08426 1.05954 2.53358015953883e-06 0.000367638420972975 DataSet_03_248
TFPI2 SP1 siRNA Mammary_gland MDA-MB-231 0.0972279 -3.36248 0.100395242703625 0.413972819854456 DataSet_03_250
TFPI2 SP1 siRNA Ovary OVSAYO 0.418637 -1.25623 0.00210960893653537 0.0814057527325062 DataSet_03_251
TFPI2 STAT1 knockout Liver Huh-7.5 2.20457 1.1405 0.00168496654938711 0.0444078493625273 DataSet_03_257
TFPI2 STAT6 siRNA Umbilical_vein HUVEC 1.75542 0.811816 0.0488782147982625 0.719345554770036 DataSet_03_264
TFPI2 TET1 siRNA Embryo NCCIT 0.533837 -0.90553 0.000131536989390313 0.00399073588365628 DataSet_03_269
TFPI2 TET2 siRNA Embryo NCCIT 0.601987 -0.732195 0.000199604475410213 0.00341569861114966 DataSet_03_270
TFPI2 TET3 siRNA Embryo NCCIT 0.596678 -0.744975 0.000294638069815463 0.00757961312714017 DataSet_03_273
TFPI2 TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.325626 -1.61871 0.0916401783376878 0.999791649573014 DataSet_03_278
TFPI2 TP63 siRNA Skin Primary neonatal keratinocytes 0.518798 -0.946756 0.0206120717824449 0.0800069402929255 DataSet_03_281
TFPI2 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.641743 -0.639933 0.484770831185965 0.866322304144743 DataSet_03_282
TFPI2 ZNF165 siRNA Mammary_gland SUM159 4.5361 2.18145 0.294591412347957 0.999998167536832 DataSet_03_288
TFPI2 ZNF746 siRNA Colon HCT116 2.89989 1.536 - - DataSet_03_293
TFPI2 ZNF750 siRNA Skin Primary neonatal keratinocytes 0.546475 -0.871773 0.0208189515349474 0.117740192349503 DataSet_03_294
TFPI2 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 7.1282 2.83354 0.0461922184530958 0.549206735984189 DataSet_04_001
TFPI2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.38461 1.25376 0.0638078380428154 0.152958543332502 DataSet_04_002
TFPI2 CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 0.611111 -0.710493 0.940247867010294 0.976501929504731 DataSet_04_005
TFPI2 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.611111 -0.710493 0.970091914506371 0.993130278132099 DataSet_04_007
TFPI2 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.366013 -1.45003 0.29439017059697 0.627643685294714 DataSet_04_008
TFPI2 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.348837 -1.51937 0.0872830080691379 0.18459533025571 DataSet_04_010
TFPI2 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 585 9.19229 0.000508990771504212 0.00832225488835091 DataSet_04_014
TFPI2 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 2.39474 1.25987 0.336161494272544 0.423558058636664 DataSet_04_015
TFPI2 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.61039 -0.712198 0.86789861712061 0.916054490335629 DataSet_04_018
TFPI2 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.52 -0.943416 0.000453017050348812 0.136850345610058 DataSet_04_021
TFPI2 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.70707 0.771523 0.52206346684071 0.66202155494649 DataSet_04_023
TFPI2 CTCF CRISPR Liver HepG2 0.588235 -0.765535 0.293202863864284 0.885833753999373 DataSet_04_027
TFPI2 E4F1 CRISPR Liver HepG2 0.489362 -1.03103 0.0463032990987439 0.299658734245115 DataSet_04_028
TFPI2 FUBP1 shRNA Liver HepG2 0.5 -1 0.117931520051334 0.490721186266731 DataSet_04_030
TFPI2 NFX1 CRISPR Liver HepG2 2.20455 1.14048 0.0663595557841681 0.12412675799605 DataSet_04_032
TFPI2 ACTN4 CRISPR Liver HepG2 2.96296 1.56704 0.056346257285967 0.140409740251604 DataSet_04_042
TFPI2 APTX CRISPR Liver HepG2 0.588235 -0.765535 0.528412404257201 0.939130055863966 DataSet_04_069
TFPI2 CHCHD3 CRISPR Liver HepG2 2.02564 1.01838 0.0695108615348916 0.472266612682052 DataSet_04_067
TFPI2 CNOT7 CRISPR Liver HepG2 0.614173 -0.703282 0.211979330272751 0.363221910364653 DataSet_04_045
TFPI2 DNMT3B CRISPR Liver HepG2 0.531915 -0.910733 0.0631659076319237 0.250529414575009 DataSet_04_044
TFPI2 RIOK2 CRISPR Liver HepG2 1.58824 0.667425 0.660480175369321 1 DataSet_04_070
TFPI2 SEPT11 CRISPR Liver HepG2 0.552239 -0.856636 0.328308900019109 0.590440672813736 DataSet_04_068
TFPI2 CALR shRNA Liver HepG2 1.81579 0.860597 0.105629776987452 0.198116025811274 DataSet_04_053
TFPI2 CNOT7 shRNA Liver HepG2 1.73913 0.798366 0.212087438196213 0.30554125112855 DataSet_04_051
TFPI2 DDX1 shRNA Liver HepG2 3.07143 1.61891 0.129368430364847 0.33835814826111 DataSet_04_057
TFPI2 NPM1 shRNA Liver HepG2 2.11765 1.08246 0.410475279129627 0.799193506899493 DataSet_04_058
TFPI2 YBX3 shRNA Liver HepG2 1.60714 0.684498 0.354432758123772 0.549273252512808 DataSet_02_98
TFPI2 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 5.64706 2.4975 0.0544574950112938 0.178688272304565 DataSet_04_048
TFPI2 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.4375 1.78136 0.13000864052967 0.507021631741575 DataSet_04_050
TFPI2 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.203740680353189 0.384079249187347 DataSet_04_046
TFPI2 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 8.46154 3.08092 0.123233434916577 0.649093234086811 DataSet_04_076
TFPI2 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.57895 2.19502 0.0867551215083446 0.430046120909766 DataSet_04_075
TFPI2 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.42105 1.27563 0.050817500232572 0.125932357288259 DataSet_04_049
TFPI2 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.4 1.76553 0.499452406435764 0.726260344121047 DataSet_02_38
TFPI2 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.6 2.20163 0.270405515696227 0.426818682056313 DataSet_02_14
TFPI2 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.872911993568314 0.937918087833752 DataSet_02_34
TFPI2 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.8 2.26303 0.538476440655083 0.866731892064229 DataSet_02_45
TFPI2 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 13.4 3.74416 0.245755710883902 0.410137690014985 DataSet_02_35
TFPI2 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 14.6 3.8679 0.0425245818725985 0.369511003108029 DataSet_02_32
TFPI2 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 7.4 2.88753 0.0327568701807872 0.0875547354023926 DataSet_02_47
TFPI2 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 10.4 3.37851 0.264872360110435 0.447825132293082 DataSet_02_43
TFPI2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 11.6 3.53605 0.0132948506290365 0.041902496358721 DataSet_02_33
TFPI2 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 13.4 3.74416 0.259263223807014 0.425718774799084 DataSet_02_53
TFPI2 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.488372 -1.03395 0.290083987220387 0.451494511306193 DataSet_04_060
TFPI2 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.04545 1.03242 0.31473298723028 0.504756893610987 DataSet_04_064
TFPI2 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.09091 1.62803 0.223739715614007 0.661538495802509 DataSet_04_063
TFPI2 CNOT3 shRNA Lung A549 1.5334 0.616734 6.309902e-02 0.8830540 DataSet_03_340
TFPI2 TET1 siRNA Lung H1299 1.61608 0.692502 - - DataSet_03_319
TFPI2 TET1 siRNA Lung H1299 1.61608 0.692502 - - DataSet_03_321
TFPI2 AEBP1 siRNA Umbilical_vein HUVEC 1.94143 0.95712 7.341422e-02 0.563238092 DataSet_03_300
TFPI2 EZH2 knockdown Uterus Ishikawa (ISK) cell 1.57038 0.651111 - - DataSet_03_324
TFPI2 ELF3 CRISPR Bile_duct HBDEC2 1.96607 0.975315 2.680584e-04 2.380381e-03 DataSet_03_304
TFPI2 HDAC4 siRNA Liver human hepatocytes 1.64685 0.719712 2.525480e-07 1.657098e-04 DataSet_03_345
TFPI2 INO80 siRNA Muscle RD 2.0311 1.02226 - - DataSet_03_344
TFPI2 TET1 CRISPR Mammary_gland MDA-MB-231 2.27131 1.18352 1.666423e-03 1.827878e-02 DataSet_03_347
TFPI2 SKI CRISPR Blood HL60 1.66667 0.736966 8.260793e-01 0.928469241 DataSet_03_351
TFPI2 CREBBP CRISPR Brain U5-NPC 3 1.58496 0.1188859634 0.7490853 DataSet_03_356
TFPI2 PTPN14 CRISPR Brain U5-NPC 0.465665 -1.10263 4.581526e-02 0.26997021 DataSet_03_357
TFPI2 TP53 CRISPR Brain U5-NPC 3.31313 1.7282 6.932112e-02 2.047818e-01 DataSet_03_358
TFPI2 TPR shRNA Bone_marrow U2OS 2.9925 1.58135 2.817801e-01 7.170676e-01 DataSet_03_370
TFPI2 ZFP36L1 siRNA Urinary_bladder J82 5.51478 2.4633 - - DataSet_03_371
TFPI2 E2F1 siRNA Nasopharynx HK1 0.590361 -0.76033 3.152152e-01 9.722824e-01 DataSet_03_373
TFPI2 ZNF213 siRNA Mammary_gland MCF7 0.483356 -1.04884 2.119161e-01 6.592819e-01 DataSet_03_376
TFPI2 SMARCA2 shRNA Lung NCI-H1944 0.655308 -0.609755 4.828845e-03 1.778454e-01 DataSet_03_377
TFPI2 EZH2 CRISPR Ovary SKOV3 5.17681 2.37206 1.403120e-05 0.0019476999 DataSet_03_378
TFPI2 DDX5 shRNA Stomach HGC-27 0.364706 -1.45519 - - DataSet_03_379
TFPI2 ZBTB7A siRNA Stomach BGC823 1.7203 0.78266 - - DataSet_03_380
TFPI2 DNMT1 siRNA Skin Human melanoma cells 3.37935 1.75675 2.009416e-06 4.087696e-05 DataSet_03_382
TFPI2 YY1 shRNA Brain GSC1517 0.59999 -0.73699 - - DataSet_03_384
TFPI2 YY1 shRNA Brain GSC3028 0.5 -1 - - DataSet_03_386
TFPI2 TRIM8 siRNA Mammary_gland MCF7 0.329181 -1.60304 3.998257e-02 0.1344720312 DataSet_03_388
TFPI2 NFKBIA shRNA Bone_marrow U2OS 0.00224888 -8.79658 5.662401e-01 0.87005461 DataSet_03_389
TFPI2 YY1 knockdown Liver HepG2 9.75 3.2854 9.733544e-09 2.911489e-07 DataSet_03_390
TFPI2 PRDM15 CRISPR Kidney Immortalized human podocytes 0.299039 -1.7416 8.652702e-05 1.721841e-03 DataSet_03_391
TFPI2 ILF2 siRNA Stomach SGC-7901 2.04651 1.03317 0.3395528170 0.53916453 DataSet_03_393
TFPI2 ASXL1 CRISPR Embryo iPSC 3.10247 1.63342 0.0893098890 0.8048302 DataSet_03_394
TFPI2 RELA CRISPR Brain T30 3.19208 1.6745 0.2432530429 0.8400824 DataSet_03_399
TFPI2 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.94647 0.960862 3.272347e-02 0.3239928 DataSet_03_403
TFPI2 TFAP2A knockout Embryo H9 22.3585 4.48275 7.017902e-06 0.01552045 DataSet_03_405
TFPI2 STRAP knockout Nerve SK-N-AS 0.370082 -1.43408 - - DataSet_03_409
TFPI2 USP22 shRNA Liver HuH7 1.6932 0.759756 - - DataSet_03_411
TFPI2 MAEL CRISPR Liver Alexander cells 0.109608 -3.18958 - - DataSet_03_423
TFPI2 FOXP3 CRISPR Peripheral_blood Naive Treg 0.461538 -1.11548 7.709156e-01 0.894302756 DataSet_03_427
TFPI2 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 1.95607 0.967956 0.5628087600 1 DataSet_03_430
TFPI2 USP7 shRNA Skin xenograft cells 0.363992 -1.45802 0.30335404 0.4466279 DataSet_03_431
TFPI2 NFE2L1 knockout Lung A549 1.66365 0.734348 1.549092e-01 8.561383e-01 DataSet_03_433
TFPI2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.5 -1 7.730142e-01 0.867446032 DataSet_03_434
TFPI2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 7.99283 2.99871 1.755862e-01 0.90558273 DataSet_03_439
TFPI2 DAXX shRNA Mammary_gland MDA-MB-231 2.70502 1.43564 1.758167e-04 0.02965147 DataSet_03_441
TFPI2 HMG20A siRNA Mammary_gland MDA-MB-231 0.634089 -0.657244 0.0140347982 0.1789483 DataSet_03_442
TFPI2 FOSL1 siRNA Prostate MSKPCa3 0.663965 -0.59082 0.0261695027 0.3910563 DataSet_03_445
TFPI2 OGT siRNA Embryo BeWo cells 0.0543478 -4.20163 2.672323e-01 0.66237450 DataSet_03_453
TFPI2 SMARCA2 shRNA Lung HCC2302 0.241685 -2.0488 1.772089e-04 3.064636e-04 DataSet_03_455
TFPI2 SREBF2 siRNA Umbilical_vein HUVEC 0.286182 -1.805 4.844788e-04 3.130923e-02 DataSet_03_457
TFPI2 ARID1A shRNA Bile_duct MMNK1 0.281874 -1.82688 7.176282e-05 0.009924496 DataSet_03_458
TFPI2 TXNIP shRNA Cord_Blood CD34+ cells 4.75 2.24793 - - DataSet_03_461
TFPI2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.247423 -2.01495 - - DataSet_03_466
TFPI2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.93814 0.954676 - - DataSet_03_467
TFPI2 SMARCA1 shRNA Embryo_kidney HEK293T 0.618557 -0.693022 - - DataSet_03_468
TFPI2 EZH2 siRNA Umbilical_vein HUVEC 1.53696 0.620078 2.070662e-03 0.074755398 DataSet_03_473
TFPI2 CREBBP CRISPR Lymph U2932 0.25 -2 2.907850e-01 1.0000000 DataSet_03_474
TFPI2 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 7.12821 2.83354 0.006311968 0.3637527 DataSet_04_072
TFPI2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 2.38462 1.25376 0.03759533 0.10219958 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate OGT by the evidences of both expression and ChIP-seq/motif
Expression Atlas of TFPI2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines