Gene Overview
Target Gene: TRIM16
NCBI Official Symbol: TRIM16
Entrez ID: 10626
Ensembl ID: ENSG00000221926
Gene Full Name: tripartite motif containing 16
Strand: -
Gene Locus: 17p12
External Links:

TRIM16 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate TRIM16   
T(co)Fs that Repress TRIM16
The Intensity of the Gene Regulated by T(co)Fs:
TRIM16-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
TRIM16 HNF1B shRNA Ovary RMG2 4.67286 2.2243 4.11602e-14 1.39399e-11 DataSet_01_103
TRIM16 SPDEF shRNA Mammary_gland MCF7 1.9427 0.95806 0.75564 0.99999 DataSet_01_107
TRIM16 GABPA siRNA Lung A549 0.19597 -2.35129 6.36586e-12 2.92108e-09 DataSet_01_113
TRIM16 FOXM1 siRNA Central_nervous_system U87 2.68436 1.42458 - - DataSet_01_122
TRIM16 ZNF100 siRNA Gastrointestinal_tissue GIST-T1 0.55307 -0.85446 0.00048 0.01497 DataSet_01_124
TRIM16 ZNF43 siRNA Gastrointestinal_tissue GIST-T1 0.59296 -0.754 0.00114 0.02272 DataSet_01_125
TRIM16 ZNF665 siRNA Gastrointestinal_tissue GIST-T1 0.57359 -0.80192 0.00075 0.01311 DataSet_01_129
TRIM16 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.64432 -0.63414 0.00345 0.0382 DataSet_01_130
TRIM16 NFYA shRNA Cervix HeLaS3 0.53936 -0.89068 9.81993e-05 0.00468 DataSet_01_131
TRIM16 SPDEF shRNA Mammary_gland MCF7 2.43548 1.2842 4.7866e-06 0.00488 DataSet_01_135
TRIM16 EHF siRNA Corneal_epithelial Corneal epithelial cells 0.61591 -0.69921 5.48635e-06 0.00143 DataSet_01_147
TRIM16 ELK1 siRNA Peripheral_blood CD4+ T cells 403.562 8.65664 0.05088 0.15634 DataSet_01_162
TRIM16 TP53 siRNA Lung SAECs 1.81449 0.85956 0.00125 0.13502 DataSet_01_175
TRIM16 GABPA shRNA Prostate C4-2B 2114.01 11.0458 0.23722 0.43934 DataSet_01_190
TRIM16 GABPA shRNA Prostate LNCaP 1326.05 10.3729 0.46295 0.7048 DataSet_01_191
TRIM16 CREB1 shRNA Parotid_gland H3118 MEC 1.50536 0.59011 0.07988 0.38962 DataSet_01_194
TRIM16 XBP1 shRNA Mammary_gland T47D 2.08781 1.06199 3.80171e-05 0.00076 DataSet_01_203
TRIM16 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.65144 -0.6183 - - DataSet_01_210
TRIM16 EGR3 shRNA Prostate M12 0.57822 -0.7903 0.0063 0.09495 DataSet_01_212
TRIM16 FOXM1 siRNA Mammary_gland MCF7 1.91669 0.93862 0.00885 0.29252 DataSet_01_223
TRIM16 SNAI2 shRNA Skin Primary human keratinocytes 1.66423 0.73486 0.00124 0.01608 DataSet_01_225
TRIM16 FOXP1 siRNA Prostate LNCaP 0.35232 -1.50506 1.45121e-05 0.03272 DataSet_01_234
TRIM16 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.61807 -0.69416 0.00265 0.01943 DataSet_01_283
TRIM16 TFAP4 siRNA Brain BE(2)-C 0.07388 -3.75874 0.15213 0.51625 DataSet_01_295
TRIM16 ELK3 shRNA Mammary_gland MDA-MB-231 0.14591 -2.77685 1.15261e-07 1.11924e-05 DataSet_01_318
TRIM16 TP63 shRNA Head_and_neck FaDU 0.62026 -0.68905 6.04061e-05 0.00154 DataSet_01_327
TRIM16 TP63 shRNA Head_and_neck FaDU 0.62026 -0.68905 6.04061e-05 0.00154 DataSet_01_330
TRIM16 KLF7 siRNA Embryo HCE 0.60959 -0.7141 0.17105 0.99985 DataSet_01_342
TRIM16 ZNF622 shRNA Liver HepG2 0.59085 -0.75913 0.0109 0.03 DataSet_02_108
TRIM16 SNRNP70 shRNA Liver HepG2 1.95968 0.97062 0.03134 0.09164 DataSet_02_126
TRIM16 PRPF4 shRNA Liver HepG2 1.68787 0.7552 0.00236 0.03208 DataSet_02_128
TRIM16 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47402 -1.07699 0.0063 0.03012 DataSet_02_143
TRIM16 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.50515 0.58991 0.05304 0.2507 DataSet_02_144
TRIM16 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6601 -0.59924 0.32004 0.51194 DataSet_02_151
TRIM16 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.55331 0.63535 0.01109 0.24904 DataSet_02_152
TRIM16 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57643 -0.79477 0.06358 0.21696 DataSet_02_165
TRIM16 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61975 -0.69025 0.09223 0.2946 DataSet_02_166
TRIM16 ABL1 siRNA Mammary_gland MCF7 1.55593 0.637779 0.46358572660613 0.976385569407162 DataSet_03_001
TRIM16 AKT1 siRNA Mammary_gland MCF7 1.51128 0.595767 0.492365938300248 0.938324772849764 DataSet_03_002
TRIM16 ASCL1 siRNA Lung DMS79 0.629825 -0.666978 0.0857692437838238 0.747843145757434 DataSet_03_016
TRIM16 ATR siRNA Mammary_gland MCF7 1.56334 0.64463 0.45900464168672 0.999819450785634 DataSet_03_020
TRIM16 BCL6 siRNA Mammary_gland MCF7 1.79089 0.84068 0.341402456180259 0.989541443114508 DataSet_03_024
TRIM16 BRCA1 siRNA Mammary_gland MCF7 1.81565 0.860488 0.330960384887183 0.999850583334387 DataSet_03_028
TRIM16 BRCA2 siRNA Mammary_gland MCF7 1.60827 0.685513 0.432327354730862 0.999441861952364 DataSet_03_029
TRIM16 CCNA2 siRNA Mammary_gland MCF7 1.63417 0.708557 0.417790735677867 0.898367206002161 DataSet_03_034
TRIM16 CDK2 siRNA Mammary_gland MCF7 1.71072 0.774608 0.378126993794667 0.99987175116756 DataSet_03_044
TRIM16 CEBPA siRNA Mammary_gland MCF7 0.606075 -0.722432 0.409212726802767 0.999962793175751 DataSet_03_047
TRIM16 CEBPB siRNA Mammary_gland MCF7 1.63787 0.711824 0.415759299381455 0.993756826434039 DataSet_03_048
TRIM16 CENPF siRNA Mammary_gland MCF7 0.415677 -1.26646 0.169269256366713 0.999662524742916 DataSet_03_052
TRIM16 CHEK1 siRNA Mammary_gland MCF7 1.55745 0.639188 0.462640828519249 0.999587656258211 DataSet_03_053
TRIM16 CTNNB1 siRNA Mammary_gland MCF7 0.494572 -1.01575 0.25785142507904 0.999436862066063 DataSet_03_058
TRIM16 E2F1 siRNA Mammary_gland MCF7 0.249709 -2.00168 0.0471615914379727 0.999927373439084 DataSet_03_061
TRIM16 E2F5 siRNA Mammary_gland MCF7 0.506859 -0.980344 0.273196010328791 0.999540347732068 DataSet_03_062
TRIM16 ESR1 siRNA Mammary_gland MCF7 1.81645 0.861118 0.20167787213924 0.999753934970283 DataSet_03_068
TRIM16 ESRRA siRNA Mammary_gland MCF7 2.34202 1.22775 0.180832128744711 0.999964003642835 DataSet_03_072
TRIM16 FOXJ2 siRNA Mammary_gland MCF7 1.59054 0.66952 0.442628283058322 0.999965704179325 DataSet_03_088
TRIM16 FOXP1 siRNA Mammary_gland MCF7 1.5574 0.639138 0.46267437770315 0.999975993110711 DataSet_03_099
TRIM16 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.664245 -0.590213 0.0705559271854442 0.317972950316833 DataSet_03_113
TRIM16 HDAC5 siRNA Mammary_gland MCF7 0.447712 -1.15936 0.203051416628249 0.999966625300244 DataSet_03_115
TRIM16 HIC1 CRISPR Prostate PC3 1.82893 0.871001 - - DataSet_03_118
TRIM16 HIF1A siRNA Mammary_gland MCF7 1.50281 0.587666 0.498051306578992 0.999966843283762 DataSet_03_119
TRIM16 HOXB7 siRNA Mammary_gland MCF7 2.01883 1.01352 0.258796332190139 0.999977683706165 DataSet_03_127
TRIM16 HSF2 siRNA Mammary_gland MCF7 0.420661 -1.24927 0.17431793468001 0.990969613280381 DataSet_03_130
TRIM16 ID1 siRNA Mammary_gland MCF7 1.76193 0.817159 0.354140012478382 0.999926480273844 DataSet_03_133
TRIM16 JUND siRNA Mammary_gland MCF7 1.57049 0.651213 0.791531315448219 0.999848956486105 DataSet_03_145
TRIM16 Klf4 siRNA Skin Primary neonatal keratinocytes 0.221915 -2.17192 5.42797883855989e-06 0.000534285826131883 DataSet_03_147
TRIM16 MAPK1 siRNA Mammary_gland MCF7 1.70195 0.767189 0.572148878841699 0.999829384224364 DataSet_03_156
TRIM16 MITF siRNA Skin SK-MEL-5 0.5202 -0.942861 6.71379528201638e-05 0.000406262483493606 DataSet_03_168
TRIM16 MYBL2 siRNA Mammary_gland MCF7 1.58342 0.663045 0.446848006422148 0.999907476570542 DataSet_03_176
TRIM16 MYC siRNA Central_nervous_system DAOY M2.1 1.50352 0.588347 1.70457939054419e-05 7.72421236724617e-05 DataSet_03_178
TRIM16 MYC siRNA Mammary_gland MCF7 1.7349 0.794851 0.366563577109884 0.999887767096734 DataSet_03_182
TRIM16 NCOR2 siRNA Mammary_gland MCF7 1.64038 0.714034 0.414389157380726 0.999834929103349 DataSet_03_193
TRIM16 PCNA siRNA Mammary_gland MCF7 0.406043 -1.30029 0.159731022692905 0.999448838103647 DataSet_03_210
TRIM16 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.638271 -0.647758 0.00256965918170469 0.0111918683788848 DataSet_03_211
TRIM16 POLR2A siRNA Mammary_gland MCF7 0.620091 -0.689449 0.351482530728445 0.999513313282531 DataSet_03_213
TRIM16 RB1 siRNA Mammary_gland MCF7 0.516431 -0.953352 0.285410370992607 0.999890290262508 DataSet_03_219
TRIM16 SOX2 siRNA Embryo 2102Ep 0.64249 -0.638253 0.00024677022361255 0.00690081881679558 DataSet_03_242
TRIM16 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.554487 -0.850774 - - DataSet_03_246
TRIM16 SOX9 knockdown Liver HepG2 1.74246 0.801121 4.36174975646948e-05 0.00185808588059713 DataSet_03_248
TRIM16 SP1 siRNA Cervix HeLa 0.527521 -0.922699 1.89115497363551e-06 0.000195382741116875 DataSet_03_249
TRIM16 SP100 siRNA Mammary_gland MCF7 2.07991 1.05652 0.241105837264526 0.999952086018951 DataSet_03_252
TRIM16 STAT3 CRISPR Embryo hESC 1.80587 0.852692 0.0108615203052543 0.0663339451770079 DataSet_03_258
TRIM16 STAT5B siRNA Mammary_gland MCF7 0.390843 -1.35534 0.145284362825561 0.999932708473107 DataSet_03_263
TRIM16 TET2 siRNA Prostate DU145 1.5504 0.63264 - - DataSet_03_271
TRIM16 TFAP2C siRNA Mammary_gland MCF7 2.38353 1.2531 0.0147043744124732 0.296398632146617 DataSet_03_274
TRIM16 TP53 siRNA Mammary_gland MCF7 0.592788 -0.754412 0.389939801136376 0.999938217444253 DataSet_03_277
TRIM16 TP63 siRNA Skin Primary neonatal keratinocytes 1.6239 0.699459 0.0285863808154794 0.101150012509674 DataSet_03_281
TRIM16 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 2.05139 1.0366 0.138789716769086 0.745023265145178 DataSet_03_282
TRIM16 ZHX2 shRNA Kidney 786-O 1.82094 0.864682 0.000165963688243017 0.00659567654468706 DataSet_03_287
TRIM16 ZNF750 siRNA Skin Primary neonatal keratinocytes 0.370643 -1.4319 0.00454649073582619 0.055370183749445 DataSet_03_294
TRIM16 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.555775 -0.847427 0.0134882337080179 0.0684734847951322 DataSet_04_002
TRIM16 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.363173 -1.46127 0.00225780161808581 0.014484253542045 DataSet_04_012
TRIM16 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.0294384 -5.08616 0.000318560046227948 0.00630316092666642 DataSet_04_014
TRIM16 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.3983 -1.32807 0.00920646699281266 0.0310154390562613 DataSet_04_015
TRIM16 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.60633 0.683766 0.0919026617819275 0.464344537560855 DataSet_04_050
TRIM16 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.88057 0.911168 0.00649077621744524 0.473368010655576 DataSet_04_073
TRIM16 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.54757 0.630005 0.0227558823558723 0.36988468995597 DataSet_04_075
TRIM16 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.364306 -1.45678 7.7944265454176e-05 0.00338512189212764 DataSet_04_059
TRIM16 TET1 CRISPR Mammary_gland MDA-MB-231 0.295823 -1.75719 1.191529e-04 3.010425e-03 DataSet_03_347
TRIM16 SKI CRISPR Blood HL60 1.82806 0.870317 7.711446e-03 0.165920459 DataSet_03_351
TRIM16 CREBBP CRISPR Brain U5-NPC 1.76189 0.817124 0.4619132672 0.7490853 DataSet_03_356
TRIM16 PTPN14 CRISPR Brain U5-NPC 0.421321 -1.24701 2.230716e-02 0.25497367 DataSet_03_357
TRIM16 TP53 CRISPR Brain U5-NPC 2.84057 1.50618 1.178314e-02 1.623145e-01 DataSet_03_358
TRIM16 EP300 shRNA Mammary_gland MCF10AT 0.652365 -0.616248 7.342180e-03 0.061718275 DataSet_03_364
TRIM16 USP22 shRNA Liver PLC_PRF_5 cells 1.71429 0.777608 2.609751e-01 0.48210887 DataSet_03_368
TRIM16 ZFP36L1 siRNA Urinary_bladder J82 2.68085 1.42269 - - DataSet_03_371
TRIM16 GLI1 siRNA Skeletal_muscle RMS13 1.80317 0.850539 9.029429e-04 0.019953935 DataSet_03_375
TRIM16 ZNF213 siRNA Mammary_gland MCF7 0.63767 -0.649119 2.470264e-01 6.592819e-01 DataSet_03_376
TRIM16 DDX5 shRNA Stomach HGC-27 1.77202 0.825396 - - DataSet_03_379
TRIM16 NFKB2 siRNA Bone_marrow U2OS 1.58005 0.65997 6.294904e-02 0.32349026 DataSet_03_381
TRIM16 DNMT1 siRNA Skin Human melanoma cells 0.493696 -1.0183 8.803057e-08 1.068691e-05 DataSet_03_382
TRIM16 PRDM15 CRISPR Kidney Immortalized human podocytes 1.95756 0.969056 3.393440e-04 4.323321e-03 DataSet_03_391
TRIM16 ILF2 siRNA Stomach SGC-7901 2.12129 1.08494 0.0195896963 0.07804198 DataSet_03_393
TRIM16 RELA CRISPR Brain T30 1.50079 0.585726 0.3929129122 0.8400824 DataSet_03_399
TRIM16 RUNX2 shRNA Cord_blood Natural Killer Cell 0.520408 -0.942285 5.699440e-01 0.848767776 DataSet_03_416
TRIM16 MAEL CRISPR Liver Alexander cells 0.556522 -0.84549 - - DataSet_03_423
TRIM16 FOXP3 CRISPR Peripheral_blood Naive Treg 3.19981 1.67799 2.005558e-02 0.221269111 DataSet_03_427
TRIM16 USP7 shRNA Skin xenograft cells 0.393379 -1.34601 0.26600994 0.4348960 DataSet_03_431
TRIM16 POU2AF1 CRISPR Lymph SUDHL4 0.657383 -0.605193 1.401022e-03 0.014379182 DataSet_03_435
TRIM16 EP300 knockout Pancreas HPAF-II orthotopic cells 0.45848 -1.12507 1.045699e-09 9.961418e-07 DataSet_03_436
TRIM16 SETDB1 shRNA Colon HCT116 3.22039 1.68723 - - DataSet_03_440
TRIM16 HMG20A siRNA Mammary_gland MDA-MB-231 0.484691 -1.04486 0.0017872852 0.1189065 DataSet_03_442
TRIM16 PHF14 siRNA Mammary_gland MDA-MB-231 0.564821 -0.824135 0.0063759054 0.2522965 DataSet_03_443
TRIM16 IRF2 shRNA Cord_Blood CD34+ cells 2.09009 1.06357 - - DataSet_03_460
TRIM16 TXNIP shRNA Cord_Blood CD34+ cells 1.6129 0.68966 - - DataSet_03_461
TRIM16 SOX9 knockout Liver HuH7 0.646186 -0.629978 3.767084e-02 1.143558e-01 DataSet_03_463
TRIM16 SMARCA1 Cas13 Embryo_kidney HEK293T 0.500821 -0.997633 - - DataSet_03_466
TRIM16 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.555775 -0.847427 0.003948967 0.025881606 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SP100 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of TRIM16
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines