Gene Overview
| Target Gene: | Upk3b |
| NCBI Official Symbol: | Upk3b |
| Entrez ID: | 100647 |
| Ensembl ID: | ENSMUSG00000042985 |
| Gene Full Name: | uroplakin 3B |
| Strand: | + |
| Gene Locus: | 5|5 G2 |
| External Links: |
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Upk3b Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Upk3b
T(co)Fs
that Repress Upk3b
The Intensity of the Gene Regulated by T(co)Fs:
Upk3b-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Upk3b | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 0.645477 | -0.631563 | 0.0898052485886504 | 0.465216506936039 | DataSet_11_013 |
| Upk3b | Bhlha9 | knockout | Limb | Whole limb bud | 2.672 | 1.41792 | - | - | DataSet_11_016 |
| Upk3b | Cbx2 | knockout | Gonads | Embryonic gonads | 1.89058 | 0.918831 | 1.18826784016034e-07 | 5.73159610994548e-06 | DataSet_11_018 |
| Upk3b | E2f4 | knockout | Brain | Forebrain | 0.33222 | -1.58979 | - | - | DataSet_11_033 |
| Upk3b | Elf5 | knockout | Mammary_gland | Mammary gland | 0.309091 | -1.6939 | 0.0117589827986967 | 0.219388658035936 | DataSet_11_035 |
| Upk3b | Foxp1 | knockout | Eye | Lens | 0.0679612 | -3.87915 | - | - | DataSet_11_044 |
| Upk3b | Gata2 | knockout | Kidney | renal collecting duct cells | 1.59619 | 0.674634 | - | - | DataSet_11_047 |
| Upk3b | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 2.14804 | 1.10302 | 0.057100992902244 | 0.987135756219234 | DataSet_11_048 |
| Upk3b | Gata5 | knockout | Lung | Left lung | 0.430649 | -1.21542 | 0.00294480305784202 | 0.0414370150764595 | DataSet_11_051 |
| Upk3b | Gfi1 | knockout | Cord_Blood | T-cells | 0.625178 | -0.677661 | 0.401483911301345 | 0.755204849288224 | DataSet_11_053 |
| Upk3b | Hsf4 | knockout | Eye | Lens | 0.509114 | -0.973939 | 0.182817838902918 | 0.987999303842427 | DataSet_11_058 |
| Upk3b | Irf6 | knockout | Skin | Skin | 0.0761492 | -3.71503 | 0.00476127261842867 | 0.0992289403483447 | DataSet_11_062 |
| Upk3b | Klf17 | shRNA | Mammary_gland | 168FARN | 0.21131 | -2.24256 | 0.00903183052686963 | 0.0384378680315428 | DataSet_11_066 |
| Upk3b | Lhx8 | knockout | Ovary | Ovary | 3.55435 | 1.82959 | 0.000234650191183193 | 0.0108346788236522 | DataSet_11_070 |
| Upk3b | Lmx1b | knockout | Kidney | Kidney | 0.613782 | -0.704202 | 0.341593227281501 | 0.660738509713569 | DataSet_11_072 |
| Upk3b | Mafg | knockout | Embryo | Whole embryo | 0.629559 | -0.667588 | 0.358762121919503 | 1 | DataSet_11_073 |
| Upk3b | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 2.26923 | 1.1822 | - | - | DataSet_11_074 |
| Upk3b | Mkx | knockout | Tooth | PDL | 1.91252 | 0.935471 | 0.311502349489897 | 0.999970897748702 | DataSet_11_083 |
| Upk3b | Neurod1 | knockout | Eye | Pineal gland | 0.655612 | -0.609085 | 0.0386284942005442 | 0.323453208806414 | DataSet_11_087 |
| Upk3b | Neurod1 | knockout | Eye | Retina | 0.274973 | -1.86264 | 5.90339345782571e-05 | 0.0023095670638467 | DataSet_11_088 |
| Upk3b | Neurod1 | knockout | Eye | Pineal gland | 1.60752 | 0.684836 | 0.315915871376815 | 0.9983937273602 | DataSet_11_089 |
| Upk3b | Plagl2 | knockout | Intestine | Small intestine | 0.452363 | -1.14445 | 0.000119205898455611 | 0.0076539044212722 | DataSet_11_104 |
| Upk3b | Pparg | siRNA | Adipose_tissue | Preadipocytes | 0.281879 | -1.82685 | 0.485428028221059 | 0.999962577291099 | DataSet_11_105 |
| Upk3b | Prdm2 | shRNA | Muscle | C2C12 | 1.79451 | 0.843588 | 0.360842944095544 | 0.969448909238337 | DataSet_11_108 |
| Upk3b | Prox1 | knockout | Liver | Liver | 1.57804 | 0.658134 | - | - | DataSet_11_109 |
| Upk3b | Sall1 | knockout | Kidney | Kidney | 1.60058 | 0.678591 | 0.486973343395754 | 0.714600679904614 | DataSet_11_121 |
| Upk3b | Sall4 | shRNA | Embryo | ES cells | 0.661765 | -0.59561 | 0.761703009818718 | 0.999840995136314 | DataSet_11_123 |
| Upk3b | Smad4 | knockout | Aorta | Aortic arteries | 3.54878 | 1.82732 | 0.519163312165931 | 0.841056158175604 | DataSet_11_128 |
| Upk3b | Snai1 | knockout | Embryo | Embryoid body | 0.0505592 | -4.30588 | - | - | DataSet_11_129 |
| Upk3b | Sohlh2 | knockout | Ovary | Ovary | 1.64671 | 0.719583 | 6.44854913492255e-07 | 3.03732447706991e-05 | DataSet_11_135 |
| Upk3b | Sox11 | knockout | Eye | Retina | 0.4375 | -1.19264 | - | - | DataSet_11_137 |
| Upk3b | Sox17 | siRNA | Embryo | NG4 | 1.81789 | 0.862262 | 0.00633566413902017 | 0.138909101382048 | DataSet_11_139 |
| Upk3b | Spdef | knockout | Colon | Colon | 0.199027 | -2.32896 | 0.0723077014435212 | 0.997507742354799 | DataSet_11_146 |
| Upk3b | Spdef | knockout | Stomach | Stomach | 0.423576 | -1.23931 | 0.0338990910399386 | 0.734605793690245 | DataSet_11_147 |
| Upk3b | Stat3 | knockout | Lung | Lung typeII cells | 0.303194 | -1.72169 | 0.00183313238279214 | 0.480449251018387 | DataSet_11_151 |
| Upk3b | Tbx1 | knockout | Ear | Otic vesicles | 0.461589 | -1.11532 | 0.193274775399411 | 0.996209135879357 | DataSet_11_154 |
| Upk3b | Tet2 | knockout | Kidney | Kidney | 0.574127 | -0.800557 | 0.232336142402347 | 1 | DataSet_11_159 |
| Upk3b | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.85408 | 0.890701 | 0.264191191042886 | 0.999827445128963 | DataSet_11_174 |
| Upk3b | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.362425 | -1.46424 | 1.38289404183843e-06 | 0.000747652834695705 | DataSet_11_179 |
| Upk3b | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 2.25883 | 1.17557 | 4.260951e-02 | 0.9999923 | DataSet_11_187 |
| Upk3b | Pogz | knockdown | Liver | fetal liver | 0.288252 | -1.7946 | 3.710822e-02 | 0.3412992 | DataSet_11_188 |
| Upk3b | Kdm5b | knockout | Heart | left ventricles | 0.56826 | -0.815377 | 0.6957481441 | 0.9999827 | DataSet_11_210 |
| Upk3b | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 430.621 | 8.75027 | 5.133547e-08 | 8.150892e-05 | DataSet_11_192 |
| Upk3b | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 14.0526 | 3.81277 | - | - | DataSet_11_196 |
| Upk3b | Smarca4 | shRNA | Embryo | ES cells | 0.243503 | -2.03799 | - | - | DataSet_11_224 |
| Upk3b | Smarca4 | shRNA | Embryo | ES cells | 0.243503 | -2.03799 | - | - | DataSet_11_225 |
| Upk3b | Bcl11b | knockout | Main_olfactory_epithelium | main olfactory epithelium (MOE) | 2.30684 | 1.20592 | - | - | DataSet_11_207 |
| Upk3b | Ncl | siRNA | Embryo | ES cells | 0.643478 | -0.636037 | 2.172421e-01 | 0.5552522780 | DataSet_11_240 |
| Upk3b | Dnmt3a | siRNA | Embryo | iPSC | 4.14283 | 2.05062 | - | - | DataSet_11_241 |
| Upk3b | Dnmt3b | siRNA | Embryo | iPSC | 2.66938 | 1.4165 | - | - | DataSet_11_242 |
| Upk3b | Twist1 | knockout | Bone_marrow | stromal cells | 1.71215e-18 | -59.0189 | - | - | DataSet_11_244 |
| Upk3b | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.204153 | -2.29228 | 5.815048e-04 | 0.0174634577 | DataSet_11_245 |
| Upk3b | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 3.25 | 1.70044 | 1.471244e-01 | 3.048056e-01 | DataSet_11_250 |
| Upk3b | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 0.60156 | -0.73322 | 0.0440234467 | 0.3955399 | DataSet_11_256 |
| Upk3b | Eed | knockout | Spinal_cord | spinal cord | 0.171651 | -2.54245 | 3.311799e-01 | 9.999790e-01 | DataSet_11_261 |
| Upk3b | Bcl3 | knockout | Bone | Osteoblast | 0.4 | -1.32193 | 5.134279e-01 | 7.947772e-01 | DataSet_11_263 |
| Upk3b | Ctnnb1 | knockout | Embryo | MGE cells | 2.39664 | 1.26101 | 4.001863e-01 | 0.587695726 | DataSet_11_266 |
| Upk3b | Dux | knockout | Embryo | Embryo | 15.044 | 3.91111 | 8.639590e-03 | 3.877734e-02 | DataSet_11_269 |
| Upk3b | Dux | knockout | Embryo | Embryo | 15.044 | 3.91111 | 8.639576e-03 | 3.877346e-02 | DataSet_11_273 |
| Upk3b | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 0.5 | -1 | 5.577921e-01 | 7.759860e-01 | DataSet_11_276 |
| Upk3b | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 0.614861 | -0.701668 | - | - | DataSet_11_285 |
| Upk3b | Pdx1 | CRISPR | Liver | Liver | 2.13684 | 1.09548 | 9.912560e-01 | 1.000000000 | DataSet_11_286 |
| Upk3b | Usp7 | siRNA | Embryo | ES cells | 0.3 | -1.73697 | 1.626630e-02 | 0.6667924 | DataSet_11_287 |
| Upk3b | Ssrp1 | CRISPR | Embryo | ES cells | 2.21429 | 1.14684 | 5.957243e-03 | 0.12627031 | DataSet_11_296 |
| Upk3b | Phf8 | knockout | prostate | Prostate | 0.0232975 | -5.42368 | 0.1657423383 | 0.4152826 | DataSet_11_298 |
| Upk3b | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 4 | 2 | 0.0993969774 | 0.3412498 | DataSet_11_300 |
| Upk3b | Dnmt1 | knockout | Skin | Keratinocytes | 14.4244 | 3.85044 | 8.512911e-03 | 0.1191886696 | DataSet_11_303 |
| Upk3b | Satb2 | CRISPR | Colon | Colon organoid | 0.615385 | -0.70044 | 1.682249e-01 | 0.6518149 | DataSet_11_304 |
| Upk3b | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 0.5 | -1 | - | - | DataSet_11_306 |
| Upk3b | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 0.342308 | -1.54663 | 1.671432e-02 | 0.69001689 | DataSet_11_309 |
| Upk3b | Ahr | knockout | Liver | Liver | 0.109375 | -3.19265 | 3.129149e-02 | 0.3671763414 | DataSet_11_315 |
| Upk3b | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.545455 | -0.874469 | 6.276689e-01 | 7.690701e-01 | DataSet_11_319 |
| Upk3b | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.631579 | -0.662965 | 8.329486e-01 | 9.048959e-01 | DataSet_11_320 |
| Upk3b | Bud31 | knockout | Testis | Spermatogonial stem cells | 3.28842 | 1.71739 | 3.931277e-01 | 0.8600602 | DataSet_11_321 |
| Upk3b | Padi2 | knockout | Testis | Testis | 1.66667 | 0.736966 | 5.545128e-01 | 1.0000000 | DataSet_11_324 |
| Upk3b | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 4.92683 | 2.30066 | 2.813923e-01 | 0.9609895 | DataSet_11_327 |
| Upk3b | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 2.72429 | 1.44588 | - | - | DataSet_11_328 |
| Upk3b | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.111111 | -3.16992 | 9.106365e-02 | 3.318781e-01 | DataSet_11_332 |
| Upk3b | Ezh2 | knockout | Eye | Retina | 0.580843 | -0.78378 | 0.6422200540 | 1.0000000 | DataSet_11_334 |
| Upk3b | Atrx | knockout | Embryo | ES cells | 0.166667 | -2.58496 | - | - | DataSet_11_335 |
| Upk3b | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 0.486389 | -1.03982 | - | - | DataSet_11_336 |
| Upk3b | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 0.574692 | -0.79914 | 1.900883e-02 | 0.42682687 | DataSet_11_338 |
| Upk3b | Gtf2ird1 | knockout | Lip | Lip | 0.4 | -1.32193 | 9.328846e-02 | 4.565453e-01 | DataSet_11_339 |
| Upk3b | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.541613 | -0.884667 | 7.721000e-03 | 0.021466396 | DataSet_11_340 |
| Upk3b | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.9039 | 0.928961 | 4.131890e-01 | 6.644795e-01 | DataSet_11_344 |
| Upk3b | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 0.342308 | -1.54663 | 1.671432e-02 | 0.69001689 | DataSet_11_347 |
Regulation Region
Expression Atlas of Upk3b