Gene Overview
Target Gene: ASZ1
NCBI Official Symbol: ASZ1
Entrez ID: 136991
Ensembl ID: ENSG00000154438
Gene Full Name: ankyrin repeat, SAM and basic leucine zipper domain containing 1
Strand: -
Gene Locus: 7q31.2
External Links:

ASZ1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ASZ1   
T(co)Fs that Repress ASZ1
The Intensity of the Gene Regulated by T(co)Fs:
ASZ1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
ASZ1 ID1 siRNA Lung H1650 4.10455 2.03723 0.15747 0.51215 DataSet_01_118
ASZ1 ZIC2 siRNA Pancreas PANC1 1.59353 0.67223 - - DataSet_01_121
ASZ1 FOXM1 siRNA Central_nervous_system U87 0.50329 -0.99053 - - DataSet_01_122
ASZ1 NFYA shRNA Cervix HeLaS3 2.43962 1.28666 5.30149e-06 0.00089 DataSet_01_131
ASZ1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.09884 -3.33883 4.39339e-08 2.51573e-05 DataSet_01_137
ASZ1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.20742 -2.26935 0.00016 0.10287 DataSet_01_138
ASZ1 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.73156 0.79207 0.04886 0.26706 DataSet_01_154
ASZ1 HSF1 shRNA Skin A375 0.63253 -0.66079 0.76028 0.88844 DataSet_01_155
ASZ1 GABPA shRNA Prostate C4-2B 1322.3 10.3688 0.23613 0.43934 DataSet_01_190
ASZ1 GABPA shRNA Prostate LNCaP 943.626 9.88207 0.46493 0.7048 DataSet_01_191
ASZ1 GATA2 siRNA Prostate LNCaP 0.1774 -2.49491 2.44253e-07 2.53723e-05 DataSet_01_193
ASZ1 CREB1 shRNA Parotid_gland H3118 MEC 2.01796 1.0129 0.5739 0.82991 DataSet_01_194
ASZ1 TP63 siRNA Immortalized_keratinocyte HaCaT 2.05023 1.03578 - - DataSet_01_200
ASZ1 TP63 siRNA Head_and_neck SCC-012 1.83226 0.87362 - - DataSet_01_201
ASZ1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 1.56809 0.64901 - - DataSet_01_208
ASZ1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.06285 -3.99203 - - DataSet_01_210
ASZ1 LIN28A siRNA Embryo H9 0.58701 -0.76855 0.01937 0.0745 DataSet_01_215
ASZ1 ERG siRNA Prostate VCaP 0.34818 -1.52209 5.08188e-07 0.00016 DataSet_01_216
ASZ1 SNAI2 shRNA Skin Primary human keratinocytes 0.2282 -2.13165 0.89317 0.93222 DataSet_01_225
ASZ1 MSX1 siRNA Tooth Dental Pulp Cells 2.13534 1.09446 0.24409 0.37734 DataSet_01_281
ASZ1 POSTN shRNA Brain GSC272 1.87831 0.90943 0.60129 0.82364 DataSet_01_293
ASZ1 TFAP4 siRNA Brain BE(2)-C 0.29781 -1.74754 0.46815 0.51904 DataSet_01_295
ASZ1 SOX7 siRNA Umbilical_vein HUVEC 0.15487 -2.69083 0.06604 0.89788 DataSet_01_299
ASZ1 SOX17 siRNA Umbilical_vein HUVEC 0.16667 -2.58491 0.03432 0.99998 DataSet_01_300
ASZ1 PTEN shRNA Skin A431 0.58174 -0.78156 0.73027 0.84853 DataSet_01_301
ASZ1 PTEN shRNA Lung HCC827 2.06465 1.0459 0.37515 0.76831 DataSet_01_302
ASZ1 PTEN shRNA Mammary_gland SKBR3 4.32383 2.11231 0.25704 0.70635 DataSet_01_303
ASZ1 SOX9 siRNA Prostate VCaP 0.63576 -0.65344 0.22306 0.9316 DataSet_01_308
ASZ1 SOX9 siRNA Prostate VCaP 0.63576 -0.65344 0.22306 0.9316 DataSet_01_309
ASZ1 ARNT siRNA Upper_aerodigestive_tract HSC3 2.43461 1.28369 - - DataSet_01_315
ASZ1 HIF1A siRNA Oral_cavity OEC-M1 8.71571 3.12362 0.00982 0.82066 DataSet_01_348
ASZ1 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.51111 0.6896 DataSet_02_136
ASZ1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.52921 0.7159 DataSet_02_144
ASZ1 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.44991 0.7236 DataSet_02_152
ASZ1 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.0587 0.63352 DataSet_02_159
ASZ1 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.19773 0.37638 DataSet_02_160
ASZ1 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.1 -3.32193 0.45701 0.82266 DataSet_02_162
ASZ1 ZFX siRNA Prostate C4-2B 0.61538 -0.70044 0.78665 0.85352 DataSet_02_172
ASZ1 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.06435 1 DataSet_02_175
ASZ1 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.2053 1 DataSet_02_177
ASZ1 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.1285 1 DataSet_02_182
ASZ1 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.08333 -3.58496 0.03185 1 DataSet_02_183
ASZ1 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.07415 1 DataSet_02_188
ASZ1 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.18168 1 DataSet_02_192
ASZ1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.19833 1 DataSet_02_197
ASZ1 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.85714 0.89308 0.32102 1 DataSet_02_201
ASZ1 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.18097 1 DataSet_02_202
ASZ1 ASCL1 siRNA Lung DMS79 5 2.32193 0.547514300898621 0.917808908208564 DataSet_03_016
ASZ1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 3.0151 1.59221 0.193282356076654 0.806218736181477 DataSet_03_025
ASZ1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.0913403 -3.45261 1.5857894256353e-05 0.0703375281343243 DataSet_03_026
ASZ1 GATA4 siRNA Stomach AGS 2.3615 1.2397 0.412565854050151 0.907350513807834 DataSet_03_105
ASZ1 GATA6 siRNA Stomach AGS 4.30171 2.10491 0.140107406256985 0.63818942748161 DataSet_03_108
ASZ1 GATA6 siRNA Stomach KatoIII 0.499633 -1.00106 0.125687587357828 0.651079745075333 DataSet_03_109
ASZ1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 5.67612 2.5049 0.0772169805293693 0.91629919807377 DataSet_03_134
ASZ1 KLF5 siRNA Stomach AGS 2.50743 1.32621 0.329690631903218 0.763004434851542 DataSet_03_149
ASZ1 KLF5 siRNA Stomach YCC3 2.50325 1.3238 0.00187385685578612 0.0726064446748394 DataSet_03_151
ASZ1 MEF2D shRNA Liver HuH7 5.19641 2.37752 - - DataSet_03_162
ASZ1 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.97145 1.57117 0.922363354456526 0.952538434868428 DataSet_03_211
ASZ1 PPARG siRNA Peripheral_blood GM-CSF Macrophage 2.18354 1.12667 0.168541777462764 0.948211592841326 DataSet_03_214
ASZ1 SOX11 siRNA Lung_fibroblast NHLF 1.65013 0.722581 0.142236412266138 0.514779392722029 DataSet_03_238
ASZ1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.0666667 -3.90689 - - DataSet_03_246
ASZ1 SOX9 knockdown Liver HepG2 1.78976 0.839767 0.000145090398096536 0.00364006766871442 DataSet_03_248
ASZ1 SRF siRNA Prostate LNCaP 1.52062 0.60466 0.417989033745253 0.751201225784243 DataSet_03_254
ASZ1 STAT6 siRNA Umbilical_vein HUVEC 8.83333 3.14296 0.0869305181189051 0.798957643496596 DataSet_03_264
ASZ1 TFAP2C siRNA Mammary_gland MCF7 2.27355 1.18495 0.176548644285879 0.52901077791763 DataSet_03_274
ASZ1 TFE3 siRNA Kidney UOK257-2 12.8307 3.68152 - - DataSet_03_275
ASZ1 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.148936 -2.74723 0.163731775875066 0.256053646347182 DataSet_04_004
ASZ1 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.0646745086931684 0.489628380736371 DataSet_04_008
ASZ1 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.206897 -2.27302 0.431985175697423 0.838969781913791 DataSet_04_009
ASZ1 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.172414 -2.53605 0.346497309881639 0.660052310038831 DataSet_04_020
ASZ1 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.468085 -1.09516 0.497900376524809 0.69320380058586 DataSet_04_021
ASZ1 APTX CRISPR Liver HepG2 0.137931 -2.85798 0.265296569225554 0.655195606712013 DataSet_04_025
ASZ1 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.832949970068279 0.922391288383233 DataSet_04_048
ASZ1 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.743524789838868 0.9563665899451 DataSet_04_076
ASZ1 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.6 1.848 0.251398761425143 1 DataSet_04_077
ASZ1 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.71070813901571 0.918037217021219 DataSet_04_075
ASZ1 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.824500693138209 0.915918180544348 DataSet_04_049
ASZ1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.851463058463727 0.923668820626626 DataSet_02_14
ASZ1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.86155157096204 0.934048812500474 DataSet_02_32
ASZ1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.55 -0.862496 0.72938381430742 0.950258628309833 DataSet_02_49
ASZ1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 37 5.20945 0.159196523377215 0.335043522531813 DataSet_04_061
ASZ1 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.827830219822853 0.961104715747924 DataSet_04_065
ASZ1 CNOT3 shRNA Lung A549 0.312753 -1.67691 7.478832e-02 0.8830540 DataSet_03_340
ASZ1 ZNF598 knockout Cervix HeLa 0.0619667 -4.01236 2.563235e-04 0.5704159 DataSet_03_299
ASZ1 AEBP1 siRNA Umbilical_vein HUVEC 1.81877 0.862966 3.074392e-01 0.870983358 DataSet_03_300
ASZ1 SMARCA4 siRNA Colon HCT116 7.7565 2.95541 4.248891e-01 0.6956111 DataSet_03_302
ASZ1 ELF3 knockdown Bile_duct HBDEC2 0.664975 -0.588629 7.926743e-02 2.570903e-01 DataSet_03_305
ASZ1 AEBP1 siRNA Central_nervous_system U87MG 0.563319 -0.827976 3.864706e-01 0.9999434 DataSet_03_338
ASZ1 SKI CRISPR Blood HL60 3.33333 1.73697 4.004274e-01 0.665641880 DataSet_03_351
ASZ1 ESR1 siRNA Mammary_gland MCF7 2.81868 1.49502 8.793178e-02 0.2554015018 DataSet_03_352
ASZ1 PARP1 siRNA Prostate LNCaP 0.602433 -0.731128 1.436192e-01 0.426750016 DataSet_03_354
ASZ1 DNMT3A knockout Embryo_kidney HEK293T 0.393546 -1.3454 - - DataSet_03_369
ASZ1 TPR shRNA Bone_marrow U2OS 0.256578 -1.96253 4.656458e-01 8.456530e-01 DataSet_03_370
ASZ1 E2F1 siRNA Nasopharynx HK1 1.9 0.925999 2.486016e-01 9.306553e-01 DataSet_03_373
ASZ1 NFKBIA shRNA Bone_marrow U2OS 0.000978793 -9.99671 6.675801e-01 0.87475253 DataSet_03_389
ASZ1 JAZF1 siRNA Cervix HeLa Kyoto 0.472797 -1.08071 4.343878e-02 0.612471021 DataSet_03_396
ASZ1 HMGA1 shRNA Bile_duct HUCCT1 7.25 2.85798 5.716793e-02 0.286821764 DataSet_03_400
ASZ1 E2F1 siRNA Prostate LNCaP 0.536585 -0.89812 3.810194e-01 0.7282362990 DataSet_03_413
ASZ1 E2F2 siRNA Prostate LNCaP 1.58537 0.664816 1.531516e-01 3.756051e-01 DataSet_03_414
ASZ1 USP7 shRNA Skin xenograft cells 0.647059 -0.628031 0.52440598 0.6525990 DataSet_03_431
ASZ1 PURA siRNA Cervix HeLa 18 4.16993 1.648151e-05 0.029192856 DataSet_03_444
ASZ1 CBX2 siRNA Mammary_gland MCF7 4.93632 2.30344 4.416925e-01 0.6109172247 DataSet_03_451
ASZ1 STAT3 shRNA Liver HepG2 1.58461 0.664133 8.412339e-02 0.3967514505 DataSet_03_465
ASZ1 CREBBP CRISPR Lymph U2932 16.375 4.03342 6.825627e-02 1.0000000 DataSet_03_474
ASZ1 EZH2 siRNA Prostate LNCaP 0.595745 -0.747234 6.058693e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate CNOT7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of ASZ1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines