Gene Overview
Target Gene: CAV3
NCBI Official Symbol: CAV3
Entrez ID: 859
Ensembl ID: ENSG00000182533
Gene Full Name: caveolin 3
Strand: +
Gene Locus: 3p25.3
External Links:

CAV3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CAV3   
T(co)Fs that Repress CAV3
The Intensity of the Gene Regulated by T(co)Fs:
CAV3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CAV3 ID1 siRNA Lung A549 0.4061 -1.30009 0.18839 0.42543 DataSet_01_117
CAV3 ZIC2 siRNA Pancreas PANC1 1.7 0.76553 - - DataSet_01_121
CAV3 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.76235 0.8175 0.0637 0.73376 DataSet_01_137
CAV3 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 3.91529 1.96912 0.00029 0.16255 DataSet_01_138
CAV3 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.63636 -0.65208 0.49668 0.75459 DataSet_01_154
CAV3 HSF1 shRNA Skin A375 2.83562 1.50366 0.16359 0.40342 DataSet_01_155
CAV3 GATA3 siRNA Peripheral_blood CD4+ T cells 1.59273 0.6715 0.01811 0.22966 DataSet_01_163
CAV3 TP53 siRNA Lung SAECs 2.36047 1.23907 0.00618 0.22311 DataSet_01_175
CAV3 GABPA shRNA Prostate C4-2B 899.222 9.81253 0.24002 0.43934 DataSet_01_190
CAV3 GABPA shRNA Prostate LNCaP 474.207 8.88937 0.46386 0.7048 DataSet_01_191
CAV3 CREB1 shRNA Parotid_gland H3118 MEC 1.8862 0.91549 0.88671 0.95907 DataSet_01_194
CAV3 TP63 siRNA Immortalized_keratinocyte HaCaT RG 3.38209 1.75791 - - DataSet_01_196
CAV3 TP63 siRNA Immortalized_keratinocyte HaCaT 2.14579 1.10151 - - DataSet_01_200
CAV3 HIC1 shRNA Mammary_gland HBL100 0.54001 -0.88895 - - DataSet_01_205
CAV3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.47749 -1.06645 - - DataSet_01_209
CAV3 LIN28A siRNA Embryo H9 4.36027 2.12442 0.00038 0.00696 DataSet_01_215
CAV3 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 0.48406 -1.04674 0.11936 0.27289 DataSet_01_217
CAV3 KLF2 shRNA Bone_marrow RPMI8226 1.92321 0.94352 0.16539 0.76608 DataSet_01_226
CAV3 MYC shRNA Soft_tissue HT1080 1.51457 0.59891 - - DataSet_01_237
CAV3 NFYB siRNA Bone_marrow U2OS ER-HA-E2F1 2.06075 1.04317 0.0871 0.40843 DataSet_01_238
CAV3 TWIST1 shRNA Stomach CAF32 0.47852 -1.06335 0.34922 0.50822 DataSet_01_253
CAV3 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.35388 -1.49867 0.10452 0.87301 DataSet_01_290
CAV3 POSTN shRNA Brain GSC272 3.15188 1.65621 0.03732 0.52905 DataSet_01_293
CAV3 TFAP4 siRNA Brain BE(2)-C 0.18684 -2.42014 0.35302 0.51625 DataSet_01_295
CAV3 PTEN shRNA Skin A431 2.67709 1.42067 0.39542 0.58742 DataSet_01_301
CAV3 PTEN shRNA Lung HCC827 0.17521 -2.51283 0.00333 0.35214 DataSet_01_302
CAV3 PTEN shRNA Mammary_gland SKBR3 2.7078 1.43712 0.49853 0.82271 DataSet_01_303
CAV3 SOX9 siRNA Prostate VCaP 1.95625 0.96809 0.61853 0.95764 DataSet_01_308
CAV3 SOX9 siRNA Prostate VCaP 1.95625 0.96809 0.61853 0.95764 DataSet_01_309
CAV3 MYC siRNA Colon HCT116 3.57097 1.83631 0.0046 0.01069 DataSet_01_324
CAV3 HOXC6 siRNA Prostate LNCaP 1.83902 0.87894 0.02947 0.99927 DataSet_01_333
CAV3 HIF1A siRNA Oral_cavity OEC-M1 0.60539 -0.72406 0.07931 0.85151 DataSet_01_348
CAV3 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.22625 1 DataSet_02_175
CAV3 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.10476 1 DataSet_02_185
CAV3 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.15705 1 DataSet_02_188
CAV3 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.46705 1 DataSet_02_195
CAV3 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 10.3333 3.36923 0.76756 1 DataSet_02_202
CAV3 AR siRNA Prostate abl cells 0.431746 -1.21175 0.0884057753338398 0.999852161656754 DataSet_03_004
CAV3 AR siRNA Prostate LNCaP 1.78646 0.837102 0.268193942805836 1 DataSet_03_005
CAV3 ASCL1 siRNA Lung DMS79 0.394231 -1.34289 0.180144492042531 0.822307962727869 DataSet_03_016
CAV3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.634791 -0.655646 - - DataSet_03_096
CAV3 GATA4 siRNA Stomach AGS 4.43986 2.15052 0.0313216181961044 0.608549678814997 DataSet_03_105
CAV3 GATA4 siRNA Stomach KatoIII 2.5503 1.35067 0.12128744909842 0.897846043350432 DataSet_03_106
CAV3 GATA6 siRNA Stomach AGS 4.40547 2.1393 0.0923422569747246 0.571373259638678 DataSet_03_108
CAV3 GATA6 siRNA Stomach KatoIII 0.662591 -0.593811 0.510371563357877 0.867988392720869 DataSet_03_109
CAV3 HIC1 CRISPR Prostate PC3 0.616444 -0.697959 - - DataSet_03_118
CAV3 HNF4a siRNA Liver HepG2 0.59736 -0.743328 0.388189779583523 0.878787161737542 DataSet_03_126
CAV3 KLF5 siRNA Stomach AGS 4.4136 2.14196 0.0128884956146682 0.339538166101752 DataSet_03_149
CAV3 KLF5 siRNA Stomach YCC3 0.506591 -0.981107 0.28796510462773 0.651199283700239 DataSet_03_151
CAV3 MYC siRNA Colon HT29 5.99345 2.58339 - - DataSet_03_177
CAV3 NR2F2 siRNA Uterus Primary eutopic stromal cells 1.90521 0.929953 0.317063606406025 0.99947668859931 DataSet_03_202
CAV3 NR4A3 siRNA Pancreas 1.1B4 0.404536 -1.30566 1.41692296071078e-06 3.85764221754298e-05 DataSet_03_203
CAV3 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.235587 -2.08567 0.0928877860984647 0.183262118072363 DataSet_03_211
CAV3 SOX11 siRNA Lung_fibroblast NHLF 0.630474 -0.665492 0.191025240813393 0.583278932195695 DataSet_03_237
CAV3 SOX11 siRNA Lung_fibroblast NHLF 0.653391 -0.613981 0.0626490441724316 0.360098619400386 DataSet_03_238
CAV3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.380952 -1.39232 - - DataSet_03_246
CAV3 SP1 siRNA Ovary OVSAYO 0.280727 -1.83276 0.00545406621568402 0.106219257263036 DataSet_03_251
CAV3 STAT3 CRISPR Embryo hESC 0.207846 -2.26641 0.00409346046120653 0.0454198777064204 DataSet_03_258
CAV3 STAT6 siRNA Umbilical_vein HUVEC 0.276596 -1.85415 0.107459760657774 0.809837661542527 DataSet_03_264
CAV3 TFAP2C siRNA Mammary_gland MCF7 1.73069 0.791346 0.298420317481801 0.631078030507583 DataSet_03_274
CAV3 TFE3 siRNA Kidney UOK257-2 0.652012 -0.61703 - - DataSet_03_275
CAV3 ZNF165 siRNA Mammary_gland WHIM12 1.5862 0.665578 0.980101656446793 0.999997668745677 DataSet_03_289
CAV3 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.9 1.53605 0.473392324428197 0.707256036619594 DataSet_02_38
CAV3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.648427691584298 0.786106514799346 DataSet_02_14
CAV3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.0516920384226125 0.134648649249254 DataSet_02_34
CAV3 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 14.1 3.81762 0.0877333648521785 0.567572697342912 DataSet_02_45
CAV3 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.9 0.925999 0.48009306664341 0.659334851383708 DataSet_02_35
CAV3 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 12.75 3.67243 0.0959429500641573 0.415089980903254 DataSet_02_32
CAV3 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.71429 2.23704 0.427043586165366 0.794680643681293 DataSet_02_49
CAV3 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.7 0.765535 0.696534394987927 0.824514482552141 DataSet_02_33
CAV3 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.9 2.29278 0.216579214558295 0.376369079278198 DataSet_02_53
CAV3 CNOT3 shRNA Lung A549 0.199273 -2.32718 4.712693e-05 0.2551098 DataSet_03_340
CAV3 ELF3 CRISPR Bile_duct HBDEC2 0.250324 -1.99813 2.988507e-06 2.004820e-04 DataSet_03_304
CAV3 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.630833 -0.66467 2.764337e-02 0.6330193 DataSet_03_306
CAV3 EZH2 knockdown Colon HCT116 0.629849 -0.666922 0.267389520 0.9097852 DataSet_03_334
CAV3 EZH2 shRNA Mammary_gland LM2 0.298922 -1.74216 2.304015e-01 6.278719e-01 DataSet_03_350
CAV3 ESR1 siRNA Mammary_gland MCF7 2.80357 1.48727 2.717849e-03 0.0317339967 DataSet_03_352
CAV3 NCOA3 siRNA Mammary_gland MDA-MB-231 2.81155 1.49136 2.701880e-01 0.7767356 DataSet_03_361
CAV3 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.482315 -1.05195 6.267657e-01 7.086676e-01 DataSet_03_362
CAV3 TP53 knockout Stomach SNU1 2.98855 1.57945 0.1279595495 0.9301241 DataSet_03_365
CAV3 TPR shRNA Bone_marrow U2OS 8.29142 3.05162 3.401887e-02 2.724170e-01 DataSet_03_370
CAV3 EZH2 CRISPR Ovary SKOV3 4 2 2.152628e-01 0.4425726084 DataSet_03_378
CAV3 DDX5 shRNA Stomach HGC-27 3.5 1.80736 - - DataSet_03_379
CAV3 NFKBIA shRNA Bone_marrow U2OS 0.00152827 -9.35388 4.180976e-01 0.87005461 DataSet_03_389
CAV3 HMGA1 shRNA Bile_duct HUCCT1 1.8 0.847997 2.349299e-01 0.543358550 DataSet_03_400
CAV3 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.61538 0.691878 7.378823e-01 0.8262467 DataSet_03_403
CAV3 CDK7 shRNA Bone_marrow D458 1.72576 0.787233 1.304549e-01 0.45086346 DataSet_03_404
CAV3 TFAP2A knockout Embryo H9 1.66667 0.736966 8.858316e-01 0.92473366 DataSet_03_405
CAV3 FOXK2 shRNA Ovary OVCAR-5 0.5 -1 3.523244e-01 0.47162194 DataSet_03_419
CAV3 IKZF2 shRNA Lymph Hut78 0.471251 -1.08543 6.698956e-01 0.89704722 DataSet_03_429
CAV3 SUFU shRNA Mammary_gland HCC1954 cells 0.5 -1 0.3264174151 0.6455297 DataSet_03_437
CAV3 HMG20A siRNA Mammary_gland MDA-MB-231 0.625 -0.678072 0.4959857279 0.6737744 DataSet_03_442
CAV3 PHF14 siRNA Mammary_gland MDA-MB-231 0.166667 -2.58496 0.0356290645 0.3902385 DataSet_03_443
CAV3 FOSL1 siRNA Prostate MSKPCa3 0.583333 -0.777608 0.6639235623 0.8202541 DataSet_03_445
CAV3 RELB CRISPR Colon SW480 0.5 -1 4.904611e-01 6.403792e-01 DataSet_03_449
CAV3 OGT siRNA Embryo BeWo cells 0.333333 -1.58496 6.210505e-01 0.86430942 DataSet_03_453
CAV3 ZFP36L1 CRISPR Lung NCI-H1876 0.551092 -0.859634 7.430229e-01 0.992381486 DataSet_03_454
CAV3 PPARG siRNA Aortic_valve Valvular endothelial cell 0.444444 -1.16992 6.581337e-01 8.861775e-01 DataSet_03_456
CAV3 ARID1A shRNA Bile_duct MMNK1 0.548448 -0.866572 3.423922e-01 0.564818635 DataSet_03_458
CAV3 PARP1 knockout Embryo_kidney HEK293a 23 4.52356 5.385736e-03 1.895141e-02 DataSet_03_464
CAV3 STAT3 shRNA Liver HepG2 2 1 7.191973e-01 0.8592344917 DataSet_03_465
CAV3 SMARCA1 Cas13 Embryo_kidney HEK293T 0.336449 -1.57154 - - DataSet_03_466
CAV3 SMARCA1 shRNA Embryo_kidney HEK293T 0.542056 -0.883486 - - DataSet_03_468
Regulation Region
 
T(co)Fs that significantly regulate BCL11A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CAV3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines