Gene Overview
| Target Gene: | Gfi1 |
| NCBI Official Symbol: | Gfi1 |
| Entrez ID: | 14581 |
| Ensembl ID: | ENSMUSG00000029275 |
| Gene Full Name: | growth factor independent 1 transcription repressor |
| Strand: | - |
| Gene Locus: | 5 F|5 52.23 cM |
| External Links: |
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Gfi1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Gfi1
T(co)Fs
that Repress Gfi1
The Intensity of the Gene Regulated by T(co)Fs:
Gfi1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Gfi1 | Adnp | knockout | Embryo | Whole embryonic body | 1.84444 | 0.883186 | 0.329268055911463 | 0.661208640085067 | DataSet_11_001 |
| Gfi1 | Ahr | knockout | Lung | Lung | 2.49703 | 1.32021 | 0.505651034875602 | 0.999996968611848 | DataSet_11_003 |
| Gfi1 | Atf3 | knockout | Mammary_gland | Breast tumor-associated macrophage | 1.63229 | 0.706895 | 0.174249527025182 | 1 | DataSet_11_006 |
| Gfi1 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 4.1579 | 2.05585 | 0.0403348606526603 | 0.363016956216841 | DataSet_11_014 |
| Gfi1 | Bcl6 | knockout | Bone_marrow | Myeloid cells | 0.207485 | -2.26892 | 4.40183595179084e-09 | 1.82596958952188e-06 | DataSet_11_015 |
| Gfi1 | Bhlha9 | knockout | Limb | Whole limb bud | 0.311315 | -1.68355 | - | - | DataSet_11_016 |
| Gfi1 | Cebpa | shRNA | Bone_marrow | Marrow progenitors | 4.16965 | 2.05993 | 0.000176503727446574 | 0.0157969694796866 | DataSet_11_019 |
| Gfi1 | Dmrt1 | knockout | Testis | Juvenile testes | 2.98109 | 1.57584 | 0.000350964088062028 | 0.150446102933723 | DataSet_11_025 |
| Gfi1 | Dmrt1 | knockout | Testis | Juvenile testes | 1.77742 | 0.829786 | 0.0358737255839818 | 0.932139260123802 | DataSet_11_026 |
| Gfi1 | Dmrt1 | knockout | Testis | Juvenile testes | 2.35277 | 1.23436 | 0.0120993727825705 | 0.599208831299486 | DataSet_11_028 |
| Gfi1 | E2f4 | knockout | Brain | Forebrain | 0.264277 | -1.91988 | - | - | DataSet_11_033 |
| Gfi1 | Foxa2 | knockout | Lung | Whole lung | 3.33037 | 1.73568 | 0.0372982190159684 | 0.362682775719738 | DataSet_11_041 |
| Gfi1 | Gfi1 | knockout | Macrophage_cells | RAW264.7 | 3.31228 | 1.72783 | 0.000818796842150639 | 0.00447912513702468 | DataSet_11_052 |
| Gfi1 | Hsf4 | knockout | Eye | Lens | 0.0960075 | -3.38071 | 0.0132315922522427 | 0.987999303842427 | DataSet_11_058 |
| Gfi1 | Irf8 | knockout | Lymph | Splenic CD11b+Gr-1 cells | 5.07878 | 2.34448 | 0.00235494380055617 | 0.0292730342366423 | DataSet_11_063 |
| Gfi1 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.422972 | -1.24137 | 0.0207722775909336 | 0.147533628800657 | DataSet_11_065 |
| Gfi1 | Lhx8 | knockout | Gonads | Oocytes | 1.7709 | 0.824482 | 0.168061675766607 | 0.993830266659981 | DataSet_11_069 |
| Gfi1 | Lmx1b | knockout | Kidney | Kidney | 1.96307 | 0.973113 | 0.0713943590612703 | 0.467469776183465 | DataSet_11_072 |
| Gfi1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.6 | -0.736966 | - | - | DataSet_11_074 |
| Gfi1 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.521797 | -0.938441 | 0.182459400345674 | 0.995635220774426 | DataSet_11_081 |
| Gfi1 | Meis1 | knockout | Bone_marrow | Immortalized myeloid cell | 1.73653 | 0.796207 | 1.34110220322109e-08 | 8.10974697801616e-07 | DataSet_11_082 |
| Gfi1 | Myb | shRNA | Hematopoietic | AML cells | 0.506425 | -0.98158 | 0.000647707424997563 | 0.0107301115829668 | DataSet_11_084 |
| Gfi1 | Neurod1 | knockout | Eye | Pineal gland | 0.541966 | -0.883725 | 0.85677087721714 | 0.999269041168372 | DataSet_11_089 |
| Gfi1 | Nhlh2 | knockout | Eye | Retina | 2.69231 | 1.42884 | 0.408555902313316 | 0.568514742136392 | DataSet_11_092 |
| Gfi1 | Nrf1 | knockdown | Liver | Liver | 0.603803 | -0.72785 | 0.639971192134877 | 0.771507337628343 | DataSet_11_096 |
| Gfi1 | Otx2 | knockout | Eye | Retina | 0.496429 | -1.01034 | 0.0977840807917692 | 0.999923528647439 | DataSet_11_097 |
| Gfi1 | Otx2 | knockout | Brain | Ganglionic eminences and septum | 1.52163 | 0.60562 | 0.110089372377056 | 0.603642956845519 | DataSet_11_098 |
| Gfi1 | Pax5 | knockout | Bone_marrow | B220+ cells | 0.556005 | -0.846829 | 0.0375770720099866 | 0.2799518859767 | DataSet_11_100 |
| Gfi1 | Pbx1 | knockout | Bone_marrow | BM cells | 1.54418 | 0.626837 | 0.126152858780951 | 0.597301419611131 | DataSet_11_102 |
| Gfi1 | Pitx2 | knockout | Eye | Cornea | 0.0952342 | -3.39238 | 0.119274065086867 | 0.492150210186877 | DataSet_11_103 |
| Gfi1 | Plagl2 | knockout | Intestine | Small intestine | 1.67188 | 0.741467 | 0.0484184478934207 | 0.262385730562229 | DataSet_11_104 |
| Gfi1 | Prox1 | knockout | Liver | Liver | 1.53097 | 0.614444 | - | - | DataSet_11_109 |
| Gfi1 | Runx1 | knockout | Lymph | ProB cells | 1.85277 | 0.889681 | 0.0132427005881356 | 0.100842403903906 | DataSet_11_116 |
| Gfi1 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 2.61409 | 1.38631 | 0.0659009615514888 | 0.999784944667092 | DataSet_11_117 |
| Gfi1 | Sall4 | shRNA | Embryo | ES cells | 0.170213 | -2.55459 | 0.00517136236713732 | 0.550047317214334 | DataSet_11_123 |
| Gfi1 | Smad4 | siRNA | Brain | bEnd3 | 0.143303 | -2.80286 | - | - | DataSet_11_127 |
| Gfi1 | Smad4 | knockout | Aorta | Aortic arteries | 1.89055 | 0.918809 | 0.0948284009863162 | 0.453193002063998 | DataSet_11_128 |
| Gfi1 | Sox11 | knockout | Brain | Cortex | 0.618365 | -0.69347 | - | - | DataSet_11_138 |
| Gfi1 | Sox2 | shRNA | Embryo | ES cells | 1.50941 | 0.593988 | - | - | DataSet_11_140 |
| Gfi1 | Sp3 | knockout | Heart | Heart | 2.7523 | 1.46064 | 0.0445588798703757 | 0.691846630845678 | DataSet_11_145 |
| Gfi1 | Stat3 | knockout | Lung | Lung typeII cells | 0.627379 | -0.67259 | 0.589657118089067 | 0.902788682829064 | DataSet_11_151 |
| Gfi1 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.552078 | -0.857056 | 0.106223903178184 | 0.883809210947411 | DataSet_11_152 |
| Gfi1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.85805 | 1.51503 | 0.013127179335769 | 0.0554184462860134 | DataSet_11_153 |
| Gfi1 | Tbx1 | knockout | Ear | Otic vesicles | 3.02805 | 1.59839 | 0.104438623141701 | 0.996209135879357 | DataSet_11_154 |
| Gfi1 | Tcf7 | shRNA | Hematopoietic | EML | 0.411444 | -1.28123 | 0.00130940813901929 | 0.179240930833643 | DataSet_11_156 |
| Gfi1 | Tet2 | shRNA | Macrophage_cells | HAFTL | 0.662871 | -0.593199 | 0.364742680206443 | 0.999974559958775 | DataSet_11_160 |
| Gfi1 | Wt1 | siRNA | Embryo_kidney | LB-22 | 3.39388 | 1.76294 | 0.0108658110546418 | 0.0768910907827794 | DataSet_11_179 |
| Gfi1 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 1.54832 | 0.630708 | 2.858742e-01 | 0.9999923 | DataSet_11_187 |
| Gfi1 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 2.5661 | 1.35958 | 7.248452e-06 | 1.003960e-04 | DataSet_11_236 |
| Gfi1 | Mapk9 | knockout | Knee | Mouse total knee | 0.495858 | -1.012 | 4.322673e-02 | 0.205111504 | DataSet_11_237 |
| Gfi1 | Kdm5b | knockout | Heart | left ventricles | 0.279896 | -1.83704 | 0.1760838712 | 0.9999827 | DataSet_11_210 |
| Gfi1 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 3.44444 | 1.78427 | 2.472455e-02 | 1.032339e-01 | DataSet_11_192 |
| Gfi1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.603297 | -0.72906 | - | - | DataSet_11_196 |
| Gfi1 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 0.000750635 | -10.3796 | - | - | DataSet_11_220 |
| Gfi1 | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 4.16965 | 2.05993 | 1.085126e-04 | 0.012640282 | DataSet_11_199 |
| Gfi1 | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 0.0541281 | -4.20748 | - | - | DataSet_11_222 |
| Gfi1 | Crebbp | knockout | Spleen | Germinal center B cells | 2.41652 | 1.27293 | 4.858043e-06 | 0.007356937 | DataSet_11_227 |
| Gfi1 | Ncl | siRNA | Embryo | ES cells | 0.222222 | -2.16992 | 2.571630e-01 | 0.5868969634 | DataSet_11_240 |
| Gfi1 | Dnmt3a | siRNA | Embryo | iPSC | 0.540372 | -0.887976 | - | - | DataSet_11_241 |
| Gfi1 | Dnmt3b | siRNA | Embryo | iPSC | 0.333674 | -1.58349 | - | - | DataSet_11_242 |
| Gfi1 | Twist1 | knockout | Bone_marrow | stromal cells | 2.17134 | 1.11859 | - | - | DataSet_11_244 |
| Gfi1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 2 | 1 | 1.839358e-01 | 0.5823767321 | DataSet_11_245 |
| Gfi1 | Fubp1 | shRNA | Brain | brain neural progenitors | 0.372544 | -1.42452 | 0.7817336065 | 1 | DataSet_11_246 |
| Gfi1 | Dnmt1 | siRNA | Embryo | Embryo | 5 | 2.32193 | - | - | DataSet_11_248 |
| Gfi1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.461538 | -1.11548 | 9.193376e-02 | 2.184939e-01 | DataSet_11_250 |
| Gfi1 | Eed | knockout | Brain | Forebrain | 8.52392 | 3.09152 | 1.930853e-04 | 2.643090e-02 | DataSet_11_258 |
| Gfi1 | Eed | knockout | Brain | hindbrain | 16.0423 | 4.00381 | 2.140323e-04 | 4.923528e-02 | DataSet_11_259 |
| Gfi1 | Eed | knockout | Brain | midbrain | 8.99026 | 3.16836 | 5.733572e-04 | 6.850537e-02 | DataSet_11_260 |
| Gfi1 | Eed | knockout | Spinal_cord | spinal cord | 4.41325 | 2.14184 | 2.555112e-03 | 5.511741e-01 | DataSet_11_261 |
| Gfi1 | Fubp1 | shRNA | Bone_marrow | BM cells | 8.23026 | 3.04094 | 2.209480e-02 | 0.348956060 | DataSet_11_262 |
| Gfi1 | Bcl3 | knockout | Bone | Osteoblast | 0.227273 | -2.1375 | 2.402810e-02 | 5.790559e-01 | DataSet_11_263 |
| Gfi1 | Arhgap35 | knockout | Ventral_spinal_cord | Ventral spinal cord | 0.571429 | -0.807355 | 2.126551e-01 | 1.000000000 | DataSet_11_264 |
| Gfi1 | Ctnnb1 | knockout | Embryo | MGE cells | 0.12764 | -2.96985 | 6.476919e-02 | 0.275856189 | DataSet_11_266 |
| Gfi1 | Dux | knockout | Embryo | Embryo | 2.68313 | 1.42392 | 1.298416e-01 | 2.866047e-01 | DataSet_11_269 |
| Gfi1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 33.8729 | 5.08206 | 3.875949e-01 | 0.81420760 | DataSet_11_272 |
| Gfi1 | Dux | knockout | Embryo | Embryo | 2.68313 | 1.42392 | 1.298416e-01 | 2.866074e-01 | DataSet_11_273 |
| Gfi1 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 1.84655 | 0.884832 | 7.832470e-01 | 8.643937e-01 | DataSet_11_275 |
| Gfi1 | Usp7 | knockout | Embryo | ES cells | 2 | 1 | 3.168483e-01 | 0.5913015 | DataSet_11_279 |
| Gfi1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 2.66667 | 1.41504 | - | - | DataSet_11_285 |
| Gfi1 | Pdx1 | CRISPR | Liver | Liver | 0.310345 | -1.68806 | 3.472789e-03 | 0.263969129 | DataSet_11_286 |
| Gfi1 | Usp7 | siRNA | Embryo | ES cells | 4 | 2 | 2.216813e-01 | 0.6667924 | DataSet_11_287 |
| Gfi1 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 0.028169 | -5.14975 | 1.908977e-02 | 0.3106771374 | DataSet_11_294 |
| Gfi1 | Ssrp1 | CRISPR | Embryo | ES cells | 2 | 1 | 7.248802e-01 | 0.84401850 | DataSet_11_296 |
| Gfi1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.609081 | -0.715293 | - | - | DataSet_11_305 |
| Gfi1 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 2.44792 | 1.29155 | - | - | DataSet_11_308 |
| Gfi1 | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 0.5 | -1 | 3.036737e-01 | 0.84403079 | DataSet_11_309 |
| Gfi1 | Suz12 | knockout | Lung | Alveolar macrophage | 4.02424 | 2.00872 | 7.700091e-02 | 0.4378234234 | DataSet_11_311 |
| Gfi1 | Actl6a | knockout | Nerve | sciatic nerve | 1.80556 | 0.852443 | 1.204229e-02 | 0.157867110 | DataSet_11_314 |
| Gfi1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.216046 | -2.21059 | 1.419792e-03 | 0.0476268553 | DataSet_11_317 |
| Gfi1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.15873 | -2.65535 | 1.387284e-03 | 1.557707e-01 | DataSet_11_319 |
| Gfi1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 1.62963 | 0.704544 | 2.404626e-01 | 4.599328e-01 | DataSet_11_320 |
| Gfi1 | Bud31 | knockout | Testis | Spermatogonial stem cells | 2.14286 | 1.09954 | 4.376004e-01 | 0.8600602 | DataSet_11_321 |
| Gfi1 | Setdb1 | shRNA | Neuron | NE-4C | 2.04852 | 1.03458 | - | - | DataSet_11_323 |
| Gfi1 | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.5 | -1 | 2.138975e-01 | 0.9832045 | DataSet_11_325 |
| Gfi1 | Dnmt1 | knockout | Brain | Cortex | 0.122098 | -3.03389 | 2.367211e-01 | 0.6579340332 | DataSet_11_329 |
| Gfi1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 0.212121 | -2.23704 | 1.587700e-02 | 1.273866e-01 | DataSet_11_332 |
| Gfi1 | Ezh2 | knockout | Eye | Retina | 1.6463 | 0.719229 | 2.822659e-04 | 8.843043e-03 | DataSet_11_333 |
| Gfi1 | Atrx | knockout | Embryo | ES cells | 0.5 | -1 | - | - | DataSet_11_335 |
| Gfi1 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 0.555556 | -0.847997 | 1.204425e-01 | 0.67893782 | DataSet_11_338 |
| Gfi1 | Gtf2ird1 | knockout | Lip | Lip | 0.5 | -1 | 2.135637e-02 | 2.847586e-01 | DataSet_11_339 |
| Gfi1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.333333 | -1.58496 | 4.029210e-02 | 0.086869428 | DataSet_11_340 |
| Gfi1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 2.19867 | 1.13663 | 0.0865278029 | 0.1713909 | DataSet_11_341 |
| Gfi1 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 0.5 | -1 | 3.036737e-01 | 0.84403079 | DataSet_11_347 |
Regulation Region
Expression Atlas of Gfi1