Gene Overview
Target Gene: IL21R
NCBI Official Symbol: IL21R
Entrez ID: 50615
Ensembl ID: ENSG00000103522
Gene Full Name: interleukin 21 receptor
Strand: +
Gene Locus: 16p12.1
External Links:

IL21R Significantly Regulated by These T(co)Fs

T(co)Fs that Activate IL21R   
T(co)Fs that Repress IL21R
The Intensity of the Gene Regulated by T(co)Fs:
IL21R-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
IL21R MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.85487 0.89132 5.35152e-09 2.37498e-07 DataSet_01_102
IL21R HOXA1 siRNA Lung_fibroblast IMR-90 4.2774 2.09673 0.00068 0.02626 DataSet_01_110
IL21R ID1 siRNA Lung A549 2.57207 1.36293 0.14713 0.37796 DataSet_01_117
IL21R ZIC2 siRNA Pancreas PANC1 6.10687 2.61043 - - DataSet_01_121
IL21R FOXM1 siRNA Central_nervous_system U87 2.28487 1.19211 - - DataSet_01_122
IL21R EGR4 siRNA Lung SBC-5 1.60237 0.68021 0.02956 0.26665 DataSet_01_132
IL21R IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.59237 1.37427 0.01155 0.32869 DataSet_01_137
IL21R POLR3A siRNA Mammary_gland MCF7 1.54367 0.62636 - - DataSet_01_139
IL21R HSF1 shRNA Skin A375 0.60309 -0.72955 0.43562 0.68653 DataSet_01_155
IL21R ELK1 siRNA Peripheral_blood CD4+ T cells 1.51367 0.59805 0.57481 0.76455 DataSet_01_162
IL21R GATA3 siRNA Peripheral_blood CD4+ T cells 1.96037 0.97113 0.46824 0.76118 DataSet_01_163
IL21R NFATC3 siRNA Peripheral_blood CD4+ T cells 0.00563 -7.47167 0.45256 0.73231 DataSet_01_166
IL21R NFKB1 siRNA Peripheral_blood CD4+ T cells 0.00837 -6.89984 0.65854 0.86383 DataSet_01_167
IL21R STAT3 siRNA Peripheral_blood CD4+ T cells 0.00612 -7.35295 0.49488 0.99183 DataSet_01_168
IL21R HOXB7 siRNA Pancreas MIA PaCa-2 0.65991 -0.59965 0.03235 0.60529 DataSet_01_169
IL21R GABPA shRNA Prostate C4-2B 675.244 9.39926 0.2365 0.43934 DataSet_01_190
IL21R GABPA shRNA Prostate LNCaP 727.31 9.50643 0.46538 0.7048 DataSet_01_191
IL21R CREB1 shRNA Parotid_gland H3118 MEC 0.52899 -0.91867 0.15456 0.50848 DataSet_01_194
IL21R TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.2766 1.18688 - - DataSet_01_196
IL21R TP63 siRNA Head_and_neck SCC-1 2.46538 1.30181 - - DataSet_01_198
IL21R TP63 siRNA Head_and_neck SCC-1 0.27883 -1.84256 - - DataSet_01_199
IL21R TP63 siRNA Immortalized_keratinocyte HaCaT 0.44861 -1.15647 - - DataSet_01_200
IL21R TP63 siRNA Head_and_neck SCC-012 0.4571 -1.1294 - - DataSet_01_201
IL21R TP63 siRNA Head_and_neck SCC-6 0.63818 -0.64795 - - DataSet_01_202
IL21R HIC1 shRNA Mammary_gland HBL100 0.50865 -0.97526 - - DataSet_01_205
IL21R MYC siRNA White_adipose_tissue Adipose stem cells 0.64559 -0.63132 0.0012 0.0183 DataSet_01_231
IL21R NFYB siRNA Bone_marrow U2OS ER-HA-E2F1 0.64131 -0.64091 0.03575 0.25309 DataSet_01_238
IL21R TWIST1 shRNA Stomach CAF32 0.29155 -1.77817 0.00033 0.01506 DataSet_01_253
IL21R TWIST1 shRNA Stomach CAF 0.53345 -0.90658 0.11378 0.59933 DataSet_01_254
IL21R FOXO3 siRNA Pancreas PANC1 0.36263 -1.46345 - - DataSet_01_267
IL21R AR shRNA Prostate CWR22Pc 1.50166 0.58656 0.10436 0.27512 DataSet_01_278
IL21R ESRRA shRNA Embryo_kidney 293T 0.63462 -0.65603 0.09776 0.706 DataSet_01_280
IL21R SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.64727 -0.62756 0.17393 0.89686 DataSet_01_290
IL21R POSTN shRNA Brain GSC272 2.0585 1.04159 0.11966 0.55804 DataSet_01_293
IL21R TFAP4 siRNA Brain BE(2)-C 0.20456 -2.28941 0.33298 0.51625 DataSet_01_295
IL21R SOX17 siRNA Umbilical_vein HUVEC 5.65254 2.4989 0.00076 0.62017 DataSet_01_300
IL21R PTEN shRNA Lung HCC827 0.57567 -0.79667 0.0194 0.48427 DataSet_01_302
IL21R FOXO1 shRNA Haematopoietic_and_lymphoid_tissue 018Z 1.99515 0.9965 0.02258 0.93203 DataSet_01_322
IL21R MYC siRNA Colon HCT116 2.20472 1.14059 0.26075 0.3261 DataSet_01_324
IL21R TOX shRNA Haematopoietic_and_lymphoid_tissue CCRF-CEM 1.76347 0.81842 0.00103 0.51427 DataSet_01_331
IL21R SOX17 siRNA Umbilical_vein HUVEC 4.53942 2.18251 - - DataSet_01_360
IL21R RBM17 shRNA Liver HepG2 0.47674 -1.06871 0.09092 0.35047 DataSet_02_100
IL21R RBFOX2 shRNA Liver HepG2 0.62791 -0.67138 0.18047 0.6638 DataSet_02_101
IL21R SAFB2 shRNA Liver HepG2 0.5283 -0.92057 0.29429 0.39463 DataSet_02_102
IL21R TAF15 shRNA Liver HepG2 0.22074 -2.17958 0.00032 0.01075 DataSet_02_106
IL21R HNRNPUL1 shRNA Liver HepG2 4.07547 2.02697 0.0288 0.07394 DataSet_02_109
IL21R GTF2F1 shRNA Liver HepG2 2.87931 1.52572 0.01059 0.22187 DataSet_02_110
IL21R BCLAF1 shRNA Liver HepG2 1.72308 0.78499 0.01861 0.06768 DataSet_02_112
IL21R U2AF2 shRNA Liver HepG2 0.48837 -1.03395 0.86387 0.91628 DataSet_02_113
IL21R PCBP1 shRNA Liver HepG2 2.87852 1.52533 0.00081 0.01339 DataSet_02_115
IL21R SUB1 shRNA Liver HepG2 2.32759 1.21883 0.06347 0.21805 DataSet_02_117
IL21R PTBP1 shRNA Liver HepG2 0.40296 -1.31128 0.00157 0.00817 DataSet_02_120
IL21R HNRNPLL shRNA Liver HepG2 14.5625 3.86419 1e-04 0.01076 DataSet_02_125
IL21R PRPF4 shRNA Liver HepG2 2.10753 1.07555 0.06538 0.15033 DataSet_02_128
IL21R TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.85106 0.88835 0.38507 0.65966 DataSet_02_129
IL21R SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65957 0.73081 0.4078 0.63452 DataSet_02_133
IL21R SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 1.85106 0.88835 0.29913 0.44364 DataSet_02_134
IL21R PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61702 -0.69661 0.34266 0.50292 DataSet_02_135
IL21R HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 0.57447 -0.7997 0.0559 0.2324 DataSet_02_136
IL21R PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.31915 1.2136 0.01179 0.2014 DataSet_02_137
IL21R TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65217 -0.61667 0.00055 0.13508 DataSet_02_140
IL21R BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.80556 0.85244 0.13537 0.29842 DataSet_02_142
IL21R RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.28042 -1.83432 0.00232 0.02244 DataSet_02_143
IL21R PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 6.53846 2.70895 0.0059 0.19727 DataSet_02_144
IL21R FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38889 -1.36257 0.08049 0.19547 DataSet_02_147
IL21R NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.52113 -0.94029 0.19415 0.39322 DataSet_02_149
IL21R SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.34211 -1.54749 0.06937 0.49906 DataSet_02_150
IL21R ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44737 -1.16046 0.03213 0.29053 DataSet_02_152
IL21R SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 2.80392 1.48745 0.05411 0.39199 DataSet_02_154
IL21R FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.51429 -0.95936 0.14343 0.37073 DataSet_02_155
IL21R HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.74453 0.80283 0.08503 0.51515 DataSet_02_156
IL21R PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.14286 2.05063 0.00249 0.0795 DataSet_02_158
IL21R TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.10409 -3.26411 0.16461 0.4052 DataSet_02_163
IL21R SSB shRNA Haematopoietic_and_lymphoid_tissue K562 5.62857 2.49277 0.02426 0.21096 DataSet_02_164
IL21R U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.69565 0.76184 0.68637 0.80245 DataSet_02_165
IL21R RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 1.69565 0.76184 0.92406 0.96422 DataSet_02_166
IL21R EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.55128 -0.85914 0.05409 0.25651 DataSet_02_167
IL21R RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59574 -0.74723 0.18631 0.31036 DataSet_02_168
IL21R U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.95652 0.96829 0.15339 0.27342 DataSet_02_170
IL21R ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.52708 0.61077 0.88758 1 DataSet_02_181
IL21R ARID1A siRNA Mammary_gland MDA-MB-157 1.79299 0.84237 - - DataSet_03_014
IL21R ASCL1 siRNA Lung DMS79 1.53261 0.615989 0.655191104619447 0.94069154431093 DataSet_03_016
IL21R CEBPB siRNA Embryo hESC 2.18523 1.12778 0.446258811397189 0.767578430531677 DataSet_03_049
IL21R E2F1 siRNA Cervix HeLa 1.60076 0.67876 0.0157297441535985 0.994339149117477 DataSet_03_060
IL21R GATA4 siRNA Stomach AGS 1.71351 0.776951 0.367743277381719 0.893137275598956 DataSet_03_105
IL21R GATA4 siRNA Stomach YCC3 2.13201 1.09221 0.0157777291005307 0.490115723137104 DataSet_03_107
IL21R GATA6 siRNA Stomach AGS 1.53809 0.621138 0.468210732987838 0.850962890832975 DataSet_03_108
IL21R GATA6 siRNA Stomach YCC3 1.5301 0.613625 0.105373011155863 0.724873723224015 DataSet_03_110
IL21R HSF1 siRNA Liver HepG2 1.5577 0.639417 0.234284261116615 1 DataSet_03_129
IL21R KLF5 siRNA Stomach KatoIII 0.609623 -0.71401 0.148139508529154 0.595534069170968 DataSet_03_150
IL21R MEF2D shRNA Liver HuH7 0.185853 -2.42776 - - DataSet_03_162
IL21R MEF2D siRNA Liver HuH7 3.15471 1.65751 - - DataSet_03_163
IL21R MYC siRNA Colon HT29 2.35334 1.23471 - - DataSet_03_177
IL21R PRRX1 CRISPR Neuroblastoma 691-MES 0.519037 -0.946091 0.0739455624374984 0.89189998148014 DataSet_03_217
IL21R SOX11 siRNA Lung_fibroblast NHLF 2.58031 1.36754 0.0206091564628231 0.322644699488926 DataSet_03_237
IL21R SOX11 siRNA Lung_fibroblast NHLF 2.01704 1.01224 0.0293347288436233 0.266934310350518 DataSet_03_238
IL21R SP1 siRNA Mammary_gland MDA-MB-231 0.455029 -1.13597 0.155248392071996 0.413972819854456 DataSet_03_250
IL21R STAT6 siRNA Umbilical_vein HUVEC 2.21323 1.14616 0.377732157642519 0.888274055212061 DataSet_03_264
IL21R TFE3 siRNA Kidney UOK257-2 0.454838 -1.13658 - - DataSet_03_275
IL21R TWIST1 siRNA Bone_marrow MSCs 2.04054 1.02895 - - DataSet_03_283
IL21R ZNF746 siRNA Colon HCT116 0.219151 -2.19 - - DataSet_03_293
IL21R CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.35533 -1.49277 0.0434656308756246 0.120413331893107 DataSet_04_002
IL21R CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.441624 -1.17911 0.00793426990824349 0.778325657111673 DataSet_04_003
IL21R CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.08772 1.62654 0.00733039338284437 0.0357339702134145 DataSet_04_004
IL21R EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.06723 1.0477 0.105447134863439 0.50135283118018 DataSet_04_008
IL21R FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.625 -0.678072 0.153618957593465 0.266758696442389 DataSet_04_010
IL21R NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 358.069 8.4841 0.000497505488820298 0.00823858315472831 DataSet_04_014
IL21R NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.142857 -2.80735 0.0199928096821753 0.0496719678982704 DataSet_04_015
IL21R PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.120473527723439 0.858378518819642 DataSet_04_016
IL21R SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.21134 -2.24236 0.00436514590896656 0.0786343354168621 DataSet_04_018
IL21R XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.52632 0.610053 0.0216364616157723 0.203358111767919 DataSet_04_021
IL21R CIZ1 CRISPR Liver HepG2 1.57194 0.652548 0.00741430716911859 0.176328357533288 DataSet_04_026
IL21R E4F1 CRISPR Liver HepG2 2.20833 1.14296 0.00179064629610654 0.151178732378897 DataSet_04_028
IL21R MECP2 CRISPR Liver HepG2 1.75723 0.813299 0.00345057399315741 0.189174027991592 DataSet_04_031
IL21R NFX1 CRISPR Liver HepG2 10.6667 3.41504 0.0003945200560571 0.0114500179402994 DataSet_04_032
IL21R SRPK2 CRISPR Liver HepG2 1.72254 0.78454 0.000193349981144824 0.0914604176088555 DataSet_04_037
IL21R YBX1 CRISPR Liver HepG2 2.05454 1.03882 0.0335206114286196 0.972884761036538 DataSet_04_039
IL21R ZC3H8 shRNA Liver HepG2 2.43411 1.28339 0.0321509197751708 0.156168731249008 DataSet_04_040
IL21R ACTN4 CRISPR Liver HepG2 0.437126 -1.19388 0.0468068392640972 0.1252639224305 DataSet_04_042
IL21R DDX20 CRISPR Liver HepG2 2.00578 1.00416 0.000347911090378547 0.0358469759629209 DataSet_04_043
IL21R RIOK2 CRISPR Liver HepG2 0.601266 -0.733925 0.330609672049025 1 DataSet_04_070
IL21R ABT1 shRNA Liver HepG2 2.68217 1.4234 0.0015451578639732 0.0108787254864652 DataSet_04_052
IL21R CALR shRNA Liver HepG2 10.3125 3.36632 4.21139776084507e-05 0.00260659433091596 DataSet_04_053
IL21R CCAR1 shRNA Liver HepG2 8.8 3.1375 3.58743867471669e-05 0.00694342969300005 DataSet_04_054
IL21R CNOT7 shRNA Liver HepG2 3.52727 1.81855 0.0150147874545169 0.0390822370030358 DataSet_04_051
IL21R PRPF6 shRNA Liver HepG2 2.86207 1.51706 0.00934492818944969 0.0740990998945228 DataSet_04_056
IL21R UBE2L3 shRNA Liver HepG2 2.85577 1.51388 0.0010063339509451 0.0115192075035767 DataSet_04_055
IL21R YBX3 shRNA Liver HepG2 0.5 -1 0.270873941734148 0.46318788222092 DataSet_02_98
IL21R DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.639594 -0.644772 0.0540668997944634 0.585009737402967 DataSet_04_047
IL21R DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.5625 0.643856 0.395097675417205 0.750028124070188 DataSet_04_050
IL21R SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.63025 0.705095 0.452389184569383 1 DataSet_04_077
IL21R SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.2521 1.17127 0.00531319332479587 0.473368010655576 DataSet_04_073
IL21R SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.7479 0.805622 0.0468378674046395 0.383575909325413 DataSet_04_075
IL21R SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.411765 -1.28011 0.00600031320583254 0.0328617153239429 DataSet_04_049
IL21R DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.02778 1.0199 0.126671761602171 0.241303463306309 DataSet_02_14
IL21R HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.2 2.07039 0.307382346976959 0.683124548818198 DataSet_02_75
IL21R HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.05556 1.03953 0.342171731296727 0.767448969094674 DataSet_02_45
IL21R NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.15278 1.1062 0.401907616018262 0.639344621315975 DataSet_02_32
IL21R SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.583333 -0.777608 0.39481625752111 0.556062428274602 DataSet_02_47
IL21R SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.06667 1.04731 0.516743819298996 0.846900884130101 DataSet_02_49
IL21R ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.372204614001207 0.53690143129835 DataSet_04_060
IL21R HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.485714 -1.04182 0.338217029919956 0.469701463604798 DataSet_04_059
IL21R DNMT1 siRNA Lung_fibroblast IMR-90 1.6026 0.680416 8.435568e-02 0.9999458 DataSet_03_317
IL21R ELF3 CRISPR Bile_duct HBDEC2 1.6177 0.693942 1.047057e-01 1.760879e-01 DataSet_03_304
IL21R SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.50102 -0.997061 3.529574e-02 0.6330193 DataSet_03_306
IL21R SNAI2 shRNA Pancreas KLM1 0.500821 -0.997634 2.298622e-01 0.58682101 DataSet_03_307
IL21R INO80 siRNA Muscle RD 1.77441 0.827337 - - DataSet_03_344
IL21R BRCA1 siRNA Mammary_gland MCF7 0.584723 -0.774174 6.502197e-03 0.7791568 DataSet_03_308
IL21R LITAF siRNA Lymph KARPAS-231 0.621504 -0.686164 3.164792e-01 0.68544654 DataSet_03_309
IL21R LITAF siRNA Lymph VAL 0.658357 -0.603059 1.293989e-01 0.632664977 DataSet_03_310
IL21R EZH2 knockdown Colon HCT116 0.340263 -1.55528 0.332950004 0.9428887 DataSet_03_334
IL21R SKI CRISPR Blood HL60 5.85714 2.5502 1.505850e-04 0.036580310 DataSet_03_351
IL21R ESR1 siRNA Mammary_gland MCF7 1.53464 0.617898 1.208395e-02 0.0771931698 DataSet_03_352
IL21R ETV5 knockdown Colon HT29 0.285714 -1.80735 2.899673e-01 0.527308910 DataSet_03_353
IL21R TET1 CRISPR Mammary_gland Hs578T 2.76639 1.46801 1.495647e-02 6.338235e-02 DataSet_03_355
IL21R CREBBP CRISPR Brain U5-NPC 0.366667 -1.44746 0.1569360776 0.7490853 DataSet_03_356
IL21R RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.38392 1.25333 6.928537e-03 1.235589e-01 DataSet_03_359
IL21R TP53 knockout Stomach SNU1 1.9395 0.955682 0.0289899320 0.9301241 DataSet_03_365
IL21R TPR shRNA Bone_marrow U2OS 1.65555 0.727312 6.763076e-03 1.141229e-01 DataSet_03_370
IL21R E2F1 siRNA Nasopharynx HK1 1.56436 0.645569 2.494588e-03 4.038341e-02 DataSet_03_373
IL21R GLI1 siRNA Skeletal_muscle RMS13 2.80351 1.48724 9.492491e-04 0.020360713 DataSet_03_375
IL21R ZNF213 siRNA Mammary_gland MCF7 0.541865 -0.883995 5.566164e-01 7.634873e-01 DataSet_03_376
IL21R SMARCA2 shRNA Lung NCI-H1944 0.559633 -0.837447 4.119549e-03 1.690529e-01 DataSet_03_377
IL21R EZH2 CRISPR Ovary SKOV3 0.416667 -1.26303 4.404434e-01 0.6136308650 DataSet_03_378
IL21R DDX5 shRNA Stomach HGC-27 3 1.58496 - - DataSet_03_379
IL21R NFKB2 siRNA Bone_marrow U2OS 0.38 -1.39593 2.327961e-02 0.20102372 DataSet_03_381
IL21R DNMT1 siRNA Skin Human melanoma cells 2.36834 1.24388 1.821636e-02 3.653172e-02 DataSet_03_382
IL21R YY1 shRNA Brain GSC1517 1.59232 0.671131 - - DataSet_03_384
IL21R TRIM8 siRNA Mammary_gland MCF7 5.75 2.52356 2.087816e-01 0.4167217724 DataSet_03_388
IL21R NFKBIA shRNA Bone_marrow U2OS 0.0775373 -3.68897 2.110724e-01 0.87005461 DataSet_03_389
IL21R YY1 knockdown Liver HepG2 0.318182 -1.65208 2.504756e-02 7.490210e-02 DataSet_03_390
IL21R ASXL1 CRISPR Embryo iPSC 0.481396 -1.0547 0.2078220892 0.8187866 DataSet_03_394
IL21R JAZF1 siRNA Cervix HeLa Kyoto 3.22657 1.69 7.476233e-01 0.962945087 DataSet_03_396
IL21R HMGA1 shRNA Bile_duct HUCCT1 5.96683 2.57696 9.219322e-06 0.004193474 DataSet_03_400
IL21R SUMO1 CRISPR Bone_marrow U2OS 1.775 0.827819 7.910683e-02 1.990109e-01 DataSet_03_401
IL21R EHF shRNA Stomach MKN7 0.0121641 -6.36123 - - DataSet_03_402
IL21R CDK7 shRNA Bone_marrow D458 12.3784 3.62975 8.653033e-03 0.15783712 DataSet_03_404
IL21R TFAP2A knockout Embryo H9 2.625 1.39232 6.379964e-02 0.16638871 DataSet_03_405
IL21R CHD1 shRNA Prostate LNCaP 0.609859 -0.713452 1.091957e-01 6.293822e-01 DataSet_03_407
IL21R MAP3K7 shRNA Prostate LNCaP 1.56761 0.648563 2.742056e-01 5.119605e-01 DataSet_03_408
IL21R STRAP knockout Nerve SK-N-AS 0.506371 -0.981732 - - DataSet_03_409
IL21R ZKSCAN3 CRISPR Colon HCT116 0.327655 -1.60975 6.906482e-02 0.439319430 DataSet_03_415
IL21R NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.66 -0.599462 6.099632e-01 0.729717607 DataSet_03_418
IL21R FOXQ1 CRISPR Lymph Primary CD4+ T cells 1.70257 0.767718 - - DataSet_03_422
IL21R MAEL CRISPR Liver Alexander cells 0.0526316 -4.24793 - - DataSet_03_423
IL21R FOXP3 CRISPR Peripheral_blood Naive Treg 1.847 0.885183 1.634551e-02 0.201778539 DataSet_03_427
IL21R USP7 shRNA Skin xenograft cells 0.366667 -1.44746 0.36482339 0.4901191 DataSet_03_431
IL21R NFE2L1 knockout Lung A549 1.64037 0.714023 5.400549e-01 9.984904e-01 DataSet_03_433
IL21R POU2AF1 CRISPR Lymph SUDHL4 2.48492 1.3132 2.295094e-04 0.007482007 DataSet_03_435
IL21R CIC knockout Brain Immortalized Astrocyte Cells 0.587542 -0.767236 2.427471e-01 6.855204e-01 DataSet_03_438
IL21R FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2 1 7.505831e-01 0.99496042 DataSet_03_439
IL21R SETDB1 shRNA Colon HCT116 0.248641 -2.00786 - - DataSet_03_440
IL21R PHF14 siRNA Mammary_gland MDA-MB-231 0.482759 -1.05063 0.1419657654 0.5844462 DataSet_03_443
IL21R PURA siRNA Cervix HeLa 0.25 -2 5.596589e-01 0.709812038 DataSet_03_444
IL21R FOSL1 siRNA Prostate MSKPCa3 2.25 1.16992 0.1092086788 0.4983845 DataSet_03_445
IL21R RELB CRISPR Colon SW480 1.53191 0.615336 5.419074e-02 2.052368e-01 DataSet_03_449
IL21R CBX2 siRNA Mammary_gland MDA-MB-231 0.256111 -1.96516 2.816299e-01 4.931148e-01 DataSet_03_450
IL21R CBX2 siRNA Mammary_gland MCF7 14.047 3.81219 1.304494e-01 0.2346962728 DataSet_03_451
IL21R OGT siRNA Embryo BeWo cells 1.85165 0.88881 6.559255e-02 0.55837810 DataSet_03_453
IL21R SREBF2 siRNA Umbilical_vein HUVEC 0.419611 -1.25287 3.386074e-01 7.580069e-01 DataSet_03_457
IL21R ARID1A shRNA Bile_duct MMNK1 0.637174 -0.650241 3.644083e-01 0.581119024 DataSet_03_458
IL21R PARP1 knockout Embryo_kidney HEK293a 4.16667 2.05889 3.981424e-03 1.475179e-02 DataSet_03_464
IL21R LIN28A siRNA Mammary_gland MCF7M 1.50227 0.587149 2.446420e-01 0.6224697 DataSet_03_469
IL21R LIN28A siRNA Mammary_gland MCF7M 1.50227 0.587149 2.446420e-01 0.6224697 DataSet_03_470
IL21R WHSC1 siRNA Prostate PC3 1.78947 0.839535 9.737871e-02 0.29074135 DataSet_03_471
IL21R EZH2 siRNA Prostate LNCaP 1.58137 0.661171 - - DataSet_03_472
IL21R EZH2 siRNA Umbilical_vein HUVEC 0.25 -2 2.449094e-01 0.516307962 DataSet_03_473
IL21R CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.441624 -1.17911 0.005844488 0.8431706 DataSet_04_071
IL21R CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.35533 -1.49277 0.01127569 0.046356688 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate POLR2G by the evidences of both expression and ChIP-seq/motif
Expression Atlas of IL21R
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines