Gene Overview
Target Gene: MYOZ3
NCBI Official Symbol: MYOZ3
Entrez ID: 91977
Ensembl ID: ENSG00000164591
Gene Full Name: myozenin 3
Strand: +
Gene Locus: 5q33.1
External Links:

MYOZ3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate MYOZ3   
T(co)Fs that Repress MYOZ3
The Intensity of the Gene Regulated by T(co)Fs:
MYOZ3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
MYOZ3 ZNF431 siRNA Gastrointestinal_tissue GIST-T1 1.60866 0.68586 0.00054 0.00561 DataSet_01_128
MYOZ3 HSF1 shRNA Skin A375 0.57885 -0.78874 0.17618 0.41991 DataSet_01_155
MYOZ3 ELK1 siRNA Peripheral_blood CD4+ T cells 1.52976 0.6133 0.04383 0.14328 DataSet_01_162
MYOZ3 GATA3 siRNA Peripheral_blood CD4+ T cells 1.57578 0.65606 0.01851 0.23221 DataSet_01_163
MYOZ3 NFKB1 siRNA Peripheral_blood CD4+ T cells 2.07015 1.04974 0.0011 0.08744 DataSet_01_167
MYOZ3 CREB1 shRNA Parotid_gland H3118 MEC 2.26392 1.17882 0.35058 0.70026 DataSet_01_194
MYOZ3 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.31875 -1.6495 - - DataSet_01_196
MYOZ3 TP63 siRNA Head_and_neck SCC-1 0.24513 -2.02836 - - DataSet_01_198
MYOZ3 TP63 siRNA Head_and_neck SCC-6 0.47023 -1.08855 - - DataSet_01_202
MYOZ3 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.58726 -0.76793 - - DataSet_01_209
MYOZ3 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 0.53747 -0.89574 0.00045 0.00978 DataSet_01_217
MYOZ3 TWIST1 shRNA Stomach CAF32 2.40414 1.26552 0.00033 0.01507 DataSet_01_253
MYOZ3 TWIST1 shRNA Stomach CAF 1.60002 0.67809 0.20035 0.67214 DataSet_01_254
MYOZ3 MSX1 siRNA Tooth Dental Pulp Cells 0.23263 -2.1039 6.0652e-06 0.00019 DataSet_01_281
MYOZ3 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.55069 -0.86068 0.18372 0.8971 DataSet_01_290
MYOZ3 SNAI2 siRNA Mammary_gland MCFDCIS 0.61239 -0.70747 0.1298 0.67758 DataSet_01_292
MYOZ3 POSTN shRNA Brain GSC272 5.16615 2.36909 0.01691 0.48721 DataSet_01_293
MYOZ3 TFAP4 siRNA Brain BE(2)-C 0.15058 -2.73139 0.27602 0.51625 DataSet_01_295
MYOZ3 SOX9 siRNA Prostate VCaP 0.66528 -0.58797 0.12957 0.9316 DataSet_01_308
MYOZ3 SOX9 siRNA Prostate VCaP 0.66528 -0.58797 0.12957 0.9316 DataSet_01_309
MYOZ3 MYC siRNA Colon HCT116 2.23381 1.15951 0.50033 0.56659 DataSet_01_324
MYOZ3 HOXC6 siRNA Prostate LNCaP 0.63799 -0.6484 0.98984 1 DataSet_01_333
MYOZ3 SAFB2 shRNA Liver HepG2 3.75 1.90689 0.02968 0.07549 DataSet_02_102
MYOZ3 FIP1L1 shRNA Liver HepG2 6.25 2.64386 0.01174 0.04507 DataSet_02_103
MYOZ3 HDGF shRNA Liver HepG2 4.5 2.16993 0.02419 0.12508 DataSet_02_104
MYOZ3 TAF15 shRNA Liver HepG2 0.5 -1 0.0637 0.1072 DataSet_02_106
MYOZ3 SSB shRNA Liver HepG2 0.25 -2 0.00437 0.01585 DataSet_02_107
MYOZ3 HNRNPUL1 shRNA Liver HepG2 4.75 2.24793 0.02366 0.06557 DataSet_02_109
MYOZ3 XRCC5 shRNA Liver HepG2 0.33333 -1.58496 0.45878 0.63964 DataSet_02_114
MYOZ3 RBM34 shRNA Liver HepG2 0.33333 -1.58496 0.47092 0.74386 DataSet_02_121
MYOZ3 PRPF4 shRNA Liver HepG2 0.31579 -1.66297 0.21197 0.33201 DataSet_02_128
MYOZ3 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.09091 -3.45943 0.01055 0.44546 DataSet_02_139
MYOZ3 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.02216 0.78527 DataSet_02_157
MYOZ3 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.01482 0.09054 DataSet_02_158
MYOZ3 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.02344 0.59238 DataSet_02_159
MYOZ3 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.10934 1 DataSet_02_173
MYOZ3 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 2.44444 1.28951 0.21386 1 DataSet_02_175
MYOZ3 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.55611 1 DataSet_02_176
MYOZ3 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.11412 1 DataSet_02_177
MYOZ3 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.93822 1 DataSet_02_179
MYOZ3 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.27163 1 DataSet_02_183
MYOZ3 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.21429 -2.22239 0.04472 1 DataSet_02_187
MYOZ3 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.10679 1 DataSet_02_188
MYOZ3 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.17849 1 DataSet_02_189
MYOZ3 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64646 -0.62936 0.94264 1 DataSet_02_190
MYOZ3 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.63112 1 DataSet_02_192
MYOZ3 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.19788 1 DataSet_02_194
MYOZ3 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.06961 1 DataSet_02_195
MYOZ3 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.15226 1 DataSet_02_198
MYOZ3 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.03156 1 DataSet_02_199
MYOZ3 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.18786 1 DataSet_02_203
MYOZ3 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.26966 1 DataSet_02_204
MYOZ3 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.09358 1 DataSet_02_205
MYOZ3 AR siRNA Prostate LNCaP 1.54766 0.630092 0.505866191135188 1 DataSet_03_005
MYOZ3 ASCL1 siRNA Lung DMS79 1.70997 0.773974 0.100821390703049 0.766960176701145 DataSet_03_016
MYOZ3 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.502623 -0.992451 0.0304240224462325 0.67286761932158 DataSet_03_025
MYOZ3 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 3.47835 1.7984 - - DataSet_03_096
MYOZ3 GATA6 siRNA Stomach AGS 1.56905 0.649894 0.102687850951101 0.589894237021904 DataSet_03_108
MYOZ3 MITF siRNA Skin Ma-Mel-15 0.658191 -0.603422 0.00438689595945169 0.0815892081766978 DataSet_03_167
MYOZ3 MITF siRNA Skin SK-MEL-5 0.609422 -0.714487 0.00172400350297808 0.00523023716858555 DataSet_03_168
MYOZ3 SOX11 siRNA Lung_fibroblast NHLF 3.35001 1.74417 0.0198179484495813 0.321417452202908 DataSet_03_237
MYOZ3 SOX11 siRNA Lung_fibroblast NHLF 4.14381 2.05096 0.00081360415472603 0.144920899698915 DataSet_03_238
MYOZ3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.66292 1.41301 - - DataSet_03_246
MYOZ3 CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 0.45 -1.152 0.155470734711261 0.492276229585749 DataSet_04_005
MYOZ3 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.1 -3.32193 0.00468849371311033 0.476887905400229 DataSet_04_009
MYOZ3 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.142857 -2.80735 0.000261674655815425 0.254793036316993 DataSet_04_013
MYOZ3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 365.64 8.51428 4.97594776090379e-05 0.00260401453525505 DataSet_04_014
MYOZ3 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.285714 -1.80736 0.0416894130936939 0.167221704205241 DataSet_04_019
MYOZ3 CTCF CRISPR Liver HepG2 0.142857 -2.80735 0.00210021354954277 0.561232598716526 DataSet_04_027
MYOZ3 SMAD2 CRISPR Liver HepG2 4.5 2.16992 0.0101099590566468 0.496843876780664 DataSet_04_034
MYOZ3 YBX1 CRISPR Liver HepG2 0.333333 -1.58496 0.0404626053465914 0.972884761036538 DataSet_04_039
MYOZ3 APTX CRISPR Liver HepG2 0.142857 -2.80735 0.247831461286834 0.841611158799117 DataSet_04_069
MYOZ3 CNOT7 CRISPR Liver HepG2 3 1.58496 0.594971555021542 0.744604519217436 DataSet_04_045
MYOZ3 ABT1 shRNA Liver HepG2 0.5 -1 0.864821183212893 0.920140789085478 DataSet_04_052
MYOZ3 CCAR1 shRNA Liver HepG2 1.66667 0.736966 0.862177358154059 0.932017881290817 DataSet_04_054
MYOZ3 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.902731267593413 0.960554945712433 DataSet_04_048
MYOZ3 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.12 1.64155 0.353779070541769 0.610164264874327 DataSet_02_38
MYOZ3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.540424106380387 0.696837519924545 DataSet_02_14
MYOZ3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.26700330062446 0.439101158007044 DataSet_02_34
MYOZ3 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.22222 1.68806 0.00535523810057696 0.393478982766751 DataSet_02_75
MYOZ3 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 8.88 3.15056 0.0042781915311882 0.369098762874113 DataSet_02_45
MYOZ3 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.76 1.91073 0.343997832450851 0.526075979413184 DataSet_02_35
MYOZ3 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 7.24 2.85599 0.0706377581113095 0.398630638779169 DataSet_02_32
MYOZ3 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.258263710135888 0.439693012498992 DataSet_02_43
MYOZ3 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.24 1.1635 0.269160711870643 0.417851160723727 DataSet_02_33
MYOZ3 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.28 1.7137 0.0219641003183131 0.0836074088436779 DataSet_02_53
MYOZ3 SMARCA4 siRNA Colon HCT116 2.04858 1.03462 5.901977e-02 8.056800e-01 DataSet_03_301
MYOZ3 ELF3 knockdown Bile_duct HBDEC2 0.557016 -0.844209 8.579500e-03 6.766077e-02 DataSet_03_305
MYOZ3 ACTR5 siRNA Muscle RD 2.3027 1.20333 - - DataSet_03_343
MYOZ3 SKI CRISPR Blood HL60 3 1.58496 3.374388e-01 0.615851377 DataSet_03_351
MYOZ3 ETV5 knockdown Colon HT29 0.25 -2 2.809806e-01 0.527308910 DataSet_03_353
MYOZ3 TET1 CRISPR Mammary_gland Hs578T 4.83223 2.27269 5.370941e-01 7.120478e-01 DataSet_03_355
MYOZ3 CREBBP CRISPR Brain U5-NPC 3.33333 1.73697 0.4304291208 0.7490853 DataSet_03_356
MYOZ3 TP53 CRISPR Brain U5-NPC 3.38889 1.76081 4.604941e-02 1.805744e-01 DataSet_03_358
MYOZ3 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.79782 0.846248 6.938284e-02 2.724237e-01 DataSet_03_359
MYOZ3 NCOA2 siRNA Uterus endometrial stromal cells 0.535714 -0.900464 0.5968577725 1 DataSet_03_360
MYOZ3 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 4.24603 2.08612 3.404261e-01 4.519679e-01 DataSet_03_362
MYOZ3 E2F1 siRNA Nasopharynx HK1 4.875 2.2854 2.769987e-01 9.722824e-01 DataSet_03_373
MYOZ3 GLI1 siRNA Skeletal_muscle RMS13 3.96728 1.98815 3.612354e-03 0.041436046 DataSet_03_375
MYOZ3 EZH2 CRISPR Ovary SKOV3 0.571429 -0.807355 2.845770e-01 0.4966825035 DataSet_03_378
MYOZ3 YY1 shRNA Brain GSC23 0.333333 -1.58496 - - DataSet_03_385
MYOZ3 TRIM8 siRNA Mammary_gland MCF7 0.210526 -2.24793 3.409535e-01 0.5487634167 DataSet_03_388
MYOZ3 NFKBIA shRNA Bone_marrow U2OS 0.0152257 -6.03735 5.535130e-01 0.87005461 DataSet_03_389
MYOZ3 YY1 knockdown Liver HepG2 0.583333 -0.777608 7.547174e-01 8.267128e-01 DataSet_03_390
MYOZ3 KDM5A CRISPR Lung GLC16 3.50076 1.80767 4.343568e-01 0.595541471 DataSet_03_392
MYOZ3 EHF shRNA Stomach MKN7 0.00294585 -8.4071 - - DataSet_03_402
MYOZ3 TFAP2A knockout Embryo H9 2.05528 1.03933 6.768958e-03 0.05582767 DataSet_03_405
MYOZ3 CHD1 shRNA Prostate LNCaP 0.587302 -0.767827 1.799625e-02 3.031080e-01 DataSet_03_407
MYOZ3 STRAP knockout Nerve SK-N-AS 0.274643 -1.86437 - - DataSet_03_409
MYOZ3 SIRT1 siRNA Pancreas PANC1 1.74091 0.799841 2.783845e-02 0.092913447 DataSet_03_410
MYOZ3 E2F6 shRNA Liver HuH7 0.498869 -1.00327 - - DataSet_03_412
MYOZ3 E2F2 siRNA Prostate LNCaP 0.25 -2 3.569988e-01 5.539935e-01 DataSet_03_414
MYOZ3 BRD4 CRISPR Lymph CD8+ T cells 0.142857 -2.80735 - - DataSet_03_420
MYOZ3 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.640625 -0.642448 - - DataSet_03_422
MYOZ3 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.428571 -1.22239 0.6701545795 1 DataSet_03_430
MYOZ3 USP7 shRNA Skin xenograft cells 0.393548 -1.34539 0.20127812 0.4348960 DataSet_03_431
MYOZ3 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.530641 -0.914193 - - DataSet_03_432
MYOZ3 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.392405 -1.34958 4.154532e-01 0.90558273 DataSet_03_439
MYOZ3 HMG20A siRNA Mammary_gland MDA-MB-231 0.5 -1 0.3015979922 0.4905665 DataSet_03_442
MYOZ3 CBX2 siRNA Mammary_gland MDA-MB-231 0.155741 -2.68278 2.055826e-01 4.011756e-01 DataSet_03_450
MYOZ3 CBX2 siRNA Mammary_gland MCF7 0.300077 -1.7366 5.899755e-01 0.7421169037 DataSet_03_451
MYOZ3 OGT siRNA Embryo BeWo cells 0.2 -2.32193 1.650119e-02 0.42255651 DataSet_03_453
MYOZ3 ARID1A shRNA Bile_duct MMNK1 0.353979 -1.49826 1.054527e-03 0.029807719 DataSet_03_458
MYOZ3 IRF2 shRNA Cord_Blood CD34+ cells 2.72727 1.44746 - - DataSet_03_460
MYOZ3 TXNIP shRNA Cord_Blood CD34+ cells 2.63492 1.39776 - - DataSet_03_461
MYOZ3 TXNIP shRNA Cord_blood ST3 8 3 2.317886e-02 0.2194921617 DataSet_03_462
MYOZ3 PARP1 knockout Embryo_kidney HEK293a 3 1.58496 7.914075e-05 5.447709e-04 DataSet_03_464
MYOZ3 LIN28A siRNA Mammary_gland MCF7M 2.53199 1.34027 4.724805e-01 0.8167664 DataSet_03_469
MYOZ3 LIN28A siRNA Mammary_gland MCF7M 2.53199 1.34027 4.724805e-01 0.8167664 DataSet_03_470
MYOZ3 WHSC1 siRNA Prostate PC3 0.521429 -0.939458 1.242336e-02 0.11634249 DataSet_03_471
MYOZ3 EZH2 siRNA Prostate LNCaP 0.404255 -1.30666 2.964154e-01 1.0000000 DataSet_03_475
MYOZ3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.615385 -0.70044 0.7211502 0.9499131 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate ERN1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of MYOZ3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines