Gene Overview
Target Gene: NCAM2
NCBI Official Symbol: NCAM2
Entrez ID: 4685
Ensembl ID: ENSG00000154654
Gene Full Name: neural cell adhesion molecule 2
Strand: +
Gene Locus: 21q21.1
External Links:

NCAM2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate NCAM2   
T(co)Fs that Repress NCAM2
The Intensity of the Gene Regulated by T(co)Fs:
NCAM2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
NCAM2 FOXA1 shRNA Prostate 22RV1 0.53192 -0.91072 - - DataSet_01_105
NCAM2 HOXA1 siRNA Lung_fibroblast IMR-90 0.44092 -1.18141 0.00556 0.08059 DataSet_01_110
NCAM2 ID1 siRNA Lung A549 1.54031 0.62322 0.3002 0.5332 DataSet_01_117
NCAM2 ZIC2 siRNA Pancreas PANC1 0.55743 -0.84314 - - DataSet_01_121
NCAM2 FOXM1 siRNA Central_nervous_system U87 5.67356 2.50426 - - DataSet_01_122
NCAM2 ZNF100 siRNA Gastrointestinal_tissue GIST-T1 0.59359 -0.75246 0.00015 0.00805 DataSet_01_124
NCAM2 ZNF85 siRNA Gastrointestinal_tissue GIST-T1 0.42325 -1.24043 2.58435e-06 0.00081 DataSet_01_126
NCAM2 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.33782 -1.56567 3.37718e-07 0.00018 DataSet_01_127
NCAM2 ZNF431 siRNA Gastrointestinal_tissue GIST-T1 0.64548 -0.63156 0.00056 0.00575 DataSet_01_128
NCAM2 ZNF665 siRNA Gastrointestinal_tissue GIST-T1 0.64027 -0.64325 0.00049 0.00994 DataSet_01_129
NCAM2 ZNF708 siRNA Gastrointestinal_tissue GIST-T1 0.5477 -0.86855 5.01115e-05 0.0034 DataSet_01_130
NCAM2 SPDEF shRNA Mammary_gland MCF7 0.65167 -0.61779 0.00068 0.03773 DataSet_01_135
NCAM2 HSF1 shRNA Skin A375 0.57303 -0.80331 0.00064 0.0091 DataSet_01_155
NCAM2 MYCN siRNA Autonomic_ganglia SKNBE2 1.59246 0.67126 0.14829 0.45826 DataSet_01_160
NCAM2 JUN siRNA Peripheral_blood CD4+ T cells 0.61821 -0.69382 0.04341 0.1793 DataSet_01_164
NCAM2 MAF siRNA Peripheral_blood CD4+ T cells 250.778 7.97027 0.12181 0.42307 DataSet_01_165
NCAM2 TP53 siRNA Lung SAECs 2.30612 1.20547 0.09456 0.48411 DataSet_01_175
NCAM2 NR5A2 siRNA Mammary_gland MCF7 0.57102 -0.80838 0.00061 0.01367 DataSet_01_182
NCAM2 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.08311 1.05874 0.00013 0.01279 DataSet_01_185
NCAM2 GATA2 siRNA Prostate LNCaP 1.53093 0.61441 0.00541 0.02153 DataSet_01_193
NCAM2 CREB1 shRNA Parotid_gland H3118 MEC 3.08656 1.626 0.73665 0.89804 DataSet_01_194
NCAM2 TP63 siRNA Head_and_neck SCC-6 3.1824 1.67012 - - DataSet_01_202
NCAM2 XBP1 shRNA Mammary_gland T47D 0.45251 -1.14398 5.27972e-05 9e-04 DataSet_01_203
NCAM2 ATF2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.95274 0.9655 0.0844 0.98802 DataSet_01_206
NCAM2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.48386 -1.04733 - - DataSet_01_209
NCAM2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.87475 0.9067 - - DataSet_01_210
NCAM2 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 2.20342 1.13975 0.13533 0.29553 DataSet_01_217
NCAM2 FOXM1 siRNA Mammary_gland MCF7 0.52501 -0.92958 0.0029 0.17603 DataSet_01_223
NCAM2 IRX1 shRNA Bone_marrow 143B 0.32414 -1.62533 0.05021 0.23081 DataSet_01_227
NCAM2 ESR2 siRNA Mammary_gland BT549 2.3511 1.23333 1.75285e-07 2.43202e-05 DataSet_01_229
NCAM2 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64681 -0.62859 0.00065 0.00529 DataSet_01_239
NCAM2 TWIST1 shRNA Stomach CAF14 1.57865 0.65869 0.07984 0.99996 DataSet_01_252
NCAM2 TWIST1 shRNA Stomach CAF32 0.24234 -2.0449 0.00246 0.02683 DataSet_01_253
NCAM2 TWIST1 shRNA Stomach CAF 0.61852 -0.6931 0.24707 0.71432 DataSet_01_254
NCAM2 AR shRNA Prostate CWR22Pc 1.85407 0.8907 0.00018 0.00674 DataSet_01_278
NCAM2 MSX1 siRNA Tooth Dental Pulp Cells 0.58538 -0.77255 0.04542 0.10032 DataSet_01_281
NCAM2 ZIC5 siRNA Skin A375 0.64324 -0.63658 - - DataSet_01_284
NCAM2 SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.09537 1.06721 0.41614 0.9251 DataSet_01_290
NCAM2 TFAP4 siRNA Brain BE(2)-C 0.35809 -1.48162 0.50705 0.53678 DataSet_01_295
NCAM2 PTEN shRNA Skin A431 0.42062 -1.24941 0.25524 0.45478 DataSet_01_301
NCAM2 PTEN shRNA Lung HCC827 0.49115 -1.02575 0.01192 0.44303 DataSet_01_302
NCAM2 PTEN shRNA Mammary_gland SKBR3 5.40352 2.4339 0.01126 0.45424 DataSet_01_303
NCAM2 ETV5 siRNA Soft_tissue hADSC 0.61537 -0.70047 0.00106 0.02056 DataSet_01_304
NCAM2 NR2E1 shRNA Neuroepithelium PBT003 0.65485 -0.61076 0.317 0.70956 DataSet_01_306
NCAM2 SOX9 siRNA Prostate VCaP 2.84393 1.50789 0.03782 0.9316 DataSet_01_308
NCAM2 SOX9 siRNA Prostate VCaP 2.84393 1.50789 0.03782 0.9316 DataSet_01_309
NCAM2 HNF4G shRNA Prostate 22RV1 1.51003 0.59458 0.00218 0.11699 DataSet_01_320
NCAM2 AR shRNA Prostate CWR22Rv1 1.97043 0.97851 3.3525e-05 0.00587 DataSet_01_323
NCAM2 MYC siRNA Colon HCT116 1.84099 0.88048 0.00275 0.00701 DataSet_01_324
NCAM2 HIF1A siRNA Oral_cavity OEC-M1 2.12282 1.08598 0.11863 0.85151 DataSet_01_348
NCAM2 ETV4 shRNA Prostate PC3 1.57589 0.65616 - - DataSet_01_356
NCAM2 FIP1L1 shRNA Liver HepG2 4 2 0.02472 0.06932 DataSet_02_103
NCAM2 SSB shRNA Liver HepG2 2 1 1 1 DataSet_02_107
NCAM2 TARDBP shRNA Liver HepG2 0.07407 -3.75489 0.28206 0.3781 DataSet_02_116
NCAM2 CEBPZ shRNA Liver HepG2 20 4.32193 0.0108 1 DataSet_02_118
NCAM2 HNRNPLL shRNA Liver HepG2 0.14815 -2.75489 0.50484 0.58426 DataSet_02_125
NCAM2 SNRNP70 shRNA Liver HepG2 0.03704 -4.75489 0.44639 0.56202 DataSet_02_126
NCAM2 SRSF3 shRNA Liver HepG2 0.03704 -4.75489 0.46125 0.615 DataSet_02_127
NCAM2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.58404 -0.77587 0.31594 0.59759 DataSet_02_129
NCAM2 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.38622 -1.3725 0.00084 0.08322 DataSet_02_147
NCAM2 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.51657 -0.95296 0.00128 0.0795 DataSet_02_158
NCAM2 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.61146 -0.70966 0.00781 0.06797 DataSet_02_168
NCAM2 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6203 -0.68897 0.27459 1 DataSet_02_180
NCAM2 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 2.36416 1.24133 0.99822 1 DataSet_02_190
NCAM2 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 1.78023 0.83206 0.06051 1 DataSet_02_200
NCAM2 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.55483 0.63675 0.05442 1 DataSet_02_202
NCAM2 ASCL1 siRNA Lung DMS79 5.96667 2.57693 0.131086176566788 0.79963178393944 DataSet_03_016
NCAM2 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.471833 -1.08365 0.142563274639485 0.786621984090896 DataSet_03_025
NCAM2 GATA2 siRNA Uterus Decidual stromal cells 0.625317 -0.677341 0.173047727660172 0.792083817899179 DataSet_03_100
NCAM2 GATA6 siRNA Stomach KatoIII 1.57073 0.651435 0.546249858872675 0.880989103588871 DataSet_03_109
NCAM2 GATA6 siRNA Stomach YCC3 1.77501 0.827827 0.120639491084075 0.744251560199952 DataSet_03_110
NCAM2 HINFP siRNA Bone_marrow U2OS 0.581834 -0.78132 0.00128864382944611 0.0288284746487951 DataSet_03_123
NCAM2 KDM3A siRNA Mammary_gland MCF7 1.51237 0.596813 0.00777028210876173 0.0768916621452879 DataSet_03_146
NCAM2 MITF siRNA Skin Ma-Mel-15 3.56321 1.83318 0.000283073657046008 0.0239480313860923 DataSet_03_166
NCAM2 MITF siRNA Skin Ma-Mel-15 3.1352 1.64856 0.000245187315349331 0.0115187225098682 DataSet_03_167
NCAM2 MTA2 siRNA Stomach SGC-7901 1.53204 0.615457 - - DataSet_03_169
NCAM2 MYB siRNA Cord_Blood CD34+ progenitor cells 28.0316 4.80898 - - DataSet_03_170
NCAM2 MYC siRNA Colon HT29 6.38438 2.67455 - - DataSet_03_177
NCAM2 MYCN siRNA Autonomic_ganglia SKNBE2 1.59246 0.671256 0.14555983922048 0.468854094203137 DataSet_03_185
NCAM2 SOX2 siRNA Mammary_gland GSC-11 1.73228 0.79267 0.000319495876616462 0.0113053808106065 DataSet_03_245
NCAM2 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.15 -2.73697 - - DataSet_03_246
NCAM2 SRF siRNA Prostate LNCaP 0.524492 -0.931007 0.000523779184878628 0.00611130700681522 DataSet_03_254
NCAM2 STAT3 CRISPR Embryo hESC 1.70414 0.769042 0.149573675056107 0.215499418979439 DataSet_03_258
NCAM2 STAT6 siRNA Umbilical_vein HUVEC 1.53403 0.617328 0.253236172006198 0.865033945420509 DataSet_03_264
NCAM2 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.425981 -1.23114 0.015452107938835 0.0768729409064164 DataSet_04_010
NCAM2 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.28477 -1.81213 0.000436614629422951 0.0116174763701763 DataSet_04_012
NCAM2 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 21.0186 4.3936 0.734841467189673 0.821688701995108 DataSet_04_014
NCAM2 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.379533 -1.3977 0.000461533446416658 0.0153372676273991 DataSet_04_015
NCAM2 PRPF6 shRNA Liver HepG2 2 1 0.9343586008981 0.977071411286856 DataSet_04_056
NCAM2 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.61939 0.695454 0.149202632339695 0.451270643989546 DataSet_02_32
NCAM2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.96364 0.973528 0.0195484179345133 0.0555238987872933 DataSet_02_33
NCAM2 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.650734 -0.61986 0.000990494101735578 0.022172332769459 DataSet_04_060
NCAM2 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.545501 -0.874345 0.0377589235647745 0.146546003073588 DataSet_04_061
NCAM2 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.346978 -1.52708 0.000115929470804041 0.00347161346547372 DataSet_04_059
NCAM2 SMARCA4 siRNA Colon HCT116 0.646895 -0.628398 2.607889e-01 9.892536e-01 DataSet_03_301
NCAM2 ELF3 CRISPR Bile_duct HBDEC2 0.4843 -1.04603 1.959224e-04 1.911338e-03 DataSet_03_304
NCAM2 ACTR5 siRNA Muscle RD 1.65083 0.723194 - - DataSet_03_343
NCAM2 INO80 siRNA Muscle RD 2.1322 1.09234 - - DataSet_03_344
NCAM2 EZH2 shRNA Mammary_gland MCF7 0.502183 -0.993715 3.878647e-06 4.838499e-04 DataSet_03_331
NCAM2 TET1 CRISPR Mammary_gland MDA-MB-231 0.198873 -2.33008 3.283536e-05 1.278982e-03 DataSet_03_347
NCAM2 EZH2 shRNA Mammary_gland LM2 2.2181 1.14933 3.017677e-01 6.934686e-01 DataSet_03_350
NCAM2 PARP1 siRNA Prostate LNCaP 0.649208 -0.623247 4.878983e-02 0.261808798 DataSet_03_354
NCAM2 TET1 CRISPR Mammary_gland Hs578T 0.410352 -1.28507 1.620096e-01 3.289526e-01 DataSet_03_355
NCAM2 PTPN14 CRISPR Brain U5-NPC 0.407143 -1.29639 1.715973e-02 0.24670427 DataSet_03_357
NCAM2 TP53 CRISPR Brain U5-NPC 1.52881 0.612412 6.971349e-01 7.628222e-01 DataSet_03_358
NCAM2 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.64029 1.40069 4.460148e-03 1.011566e-01 DataSet_03_359
NCAM2 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 3.18426 1.67096 2.223770e-05 2.010805e-04 DataSet_03_362
NCAM2 USP22 shRNA Liver PLC_PRF_5 cells 2.87065 1.52138 1.317375e-02 0.12851308 DataSet_03_368
NCAM2 E2F1 siRNA Nasopharynx HK1 0.555556 -0.847997 2.656941e-01 9.709751e-01 DataSet_03_373
NCAM2 EZH2 CRISPR Ovary SKOV3 2.1875 1.12928 9.949493e-01 1.0000000000 DataSet_03_378
NCAM2 DDX5 shRNA Stomach HGC-27 1.90363 0.928756 - - DataSet_03_379
NCAM2 NFKB2 siRNA Bone_marrow U2OS 0.6 -0.736966 4.487715e-02 0.28002694 DataSet_03_381
NCAM2 DNMT1 siRNA Skin Human melanoma cells 3.29519 1.72036 8.661333e-02 1.412920e-01 DataSet_03_382
NCAM2 YY1 shRNA Brain GSC1517 0.530769 -0.913843 - - DataSet_03_384
NCAM2 TRIM8 siRNA Mammary_gland MCF7 0.629719 -0.66722 1.267446e-04 0.0045703935 DataSet_03_388
NCAM2 NFKBIA shRNA Bone_marrow U2OS 0.374943 -1.41526 6.378025e-01 0.87005461 DataSet_03_389
NCAM2 PRDM15 CRISPR Kidney Immortalized human podocytes 1.69018 0.757175 9.163087e-01 9.481751e-01 DataSet_03_391
NCAM2 KDM5A CRISPR Lung GLC16 1.85582 0.892055 2.382320e-03 0.021566914 DataSet_03_392
NCAM2 ILF2 siRNA Stomach SGC-7901 0.5 -1 0.5815873053 0.66041517 DataSet_03_393
NCAM2 JAZF1 siRNA Cervix HeLa Kyoto 1.72429 0.786 9.309264e-02 0.726433895 DataSet_03_396
NCAM2 IKZF2 CRISPR Lymph CAR T Cell 1.63161 0.7063 7.239090e-01 0.939693315 DataSet_03_397
NCAM2 SUMO1 CRISPR Bone_marrow U2OS 1.52597 0.60973 2.249043e-02 8.941738e-02 DataSet_03_401
NCAM2 TFAP2A knockout Embryo H9 0.639421 -0.645163 2.452707e-02 0.09928307 DataSet_03_405
NCAM2 SIRT1 siRNA Pancreas PANC1 6 2.58496 2.627090e-01 0.431061807 DataSet_03_410
NCAM2 USP22 shRNA Liver HuH7 7.08565 2.8249 - - DataSet_03_411
NCAM2 E2F6 shRNA Liver HuH7 0.465587 -1.10288 - - DataSet_03_412
NCAM2 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2.11023 1.0774 6.618858e-03 0.042078636 DataSet_03_418
NCAM2 BRD4 CRISPR Lymph CD8+ T cells 1.66667 0.736966 - - DataSet_03_420
NCAM2 PRDM1 CRISPR Lymph CD8+ T cells 1.66667 0.736966 - - DataSet_03_421
NCAM2 MAEL CRISPR Liver Alexander cells 0.293333 -1.76939 - - DataSet_03_423
NCAM2 FOXP3 CRISPR Peripheral_blood Naive Treg 2 1 7.876071e-01 0.903659273 DataSet_03_427
NCAM2 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.525 -0.929611 3.058777e-02 1.000000e+00 DataSet_03_428
NCAM2 USP7 shRNA Skin xenograft cells 0.425232 -1.23368 0.25296409 0.4348960 DataSet_03_431
NCAM2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.5 1.32193 4.276818e-01 0.635167284 DataSet_03_434
NCAM2 POU2AF1 CRISPR Lymph SUDHL4 1.66667 0.736966 7.937418e-01 0.854745846 DataSet_03_435
NCAM2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.8 0.847997 9.641049e-01 1.00000000 DataSet_03_439
NCAM2 DAXX shRNA Mammary_gland MDA-MB-231 3.40642 1.76826 1.551499e-03 0.05789778 DataSet_03_441
NCAM2 PHF14 siRNA Mammary_gland MDA-MB-231 1.97059 0.978626 0.0056430675 0.2418250 DataSet_03_443
NCAM2 PURA siRNA Cervix HeLa 2.10938 1.07682 5.528129e-03 0.074814848 DataSet_03_444
NCAM2 CAMTA1 knockout Embryo_kidney HEK293T 6.5 2.70044 7.758184e-02 0.22655793 DataSet_03_448
NCAM2 CBX2 siRNA Mammary_gland MDA-MB-231 1.60896 0.686125 3.050575e-02 1.051529e-01 DataSet_03_450
NCAM2 CBX2 siRNA Mammary_gland MCF7 2.66088 1.41191 1.750907e-03 0.0083663458 DataSet_03_451
NCAM2 SREBF2 siRNA Umbilical_vein HUVEC 1.91899 0.940347 4.498895e-04 2.996757e-02 DataSet_03_457
NCAM2 SOX9 knockout Liver HuH7 0.530645 -0.914181 4.479096e-03 2.445964e-02 DataSet_03_463
NCAM2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.560976 -0.83399 - - DataSet_03_466
NCAM2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.04878 1.03477 - - DataSet_03_467
NCAM2 WHSC1 siRNA Prostate PC3 1.875 0.906891 5.188753e-01 0.70353670 DataSet_03_471
NCAM2 CREBBP CRISPR Lymph U2932 2 1 7.469436e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate RBM14 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of NCAM2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines