Gene Overview
Target Gene: OLFML2B
NCBI Official Symbol: OLFML2B
Entrez ID: 25903
Ensembl ID: ENSG00000162745
Gene Full Name: olfactomedin like 2B
Strand: -
Gene Locus: 1q23.3
External Links:

OLFML2B Significantly Regulated by These T(co)Fs

T(co)Fs that Activate OLFML2B   
T(co)Fs that Repress OLFML2B
The Intensity of the Gene Regulated by T(co)Fs:
OLFML2B-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
OLFML2B IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.73944 0.79862 0.00667 0.05728 DataSet_01_101
OLFML2B ARID1A shRNA Ovary OSE4 0.56766 -0.8169 - - DataSet_01_108
OLFML2B HOXA1 siRNA Lung_fibroblast IMR-90 1.69066 0.75759 0.10301 0.34824 DataSet_01_110
OLFML2B ZIC2 siRNA Pancreas PANC1 3.65633 1.8704 - - DataSet_01_121
OLFML2B FOXM1 siRNA Central_nervous_system U87 3.74447 1.90476 - - DataSet_01_122
OLFML2B GATA3 siRNA Peripheral_blood CD4+ T cells 1.6146 0.69117 0.02298 0.25493 DataSet_01_163
OLFML2B JUN siRNA Peripheral_blood CD4+ T cells 1.60849 0.68571 0.0255 0.12674 DataSet_01_164
OLFML2B STAT3 siRNA Peripheral_blood CD4+ T cells 98.2565 6.61848 0.16431 0.99183 DataSet_01_168
OLFML2B FOSL1 siRNA Mammary_gland BT549 0.61085 -0.7111 0.00036 0.02145 DataSet_01_171
OLFML2B ESRRG siRNA Placenta_tissue Trophoblast cells 0.53603 -0.89961 0.00895 0.12142 DataSet_01_173
OLFML2B TP53 siRNA Lung SAECs 5.36364 2.42321 0.00049 0.11835 DataSet_01_175
OLFML2B CREB1 shRNA Parotid_gland HSY 0.41782 -1.25906 0.20972 0.88093 DataSet_01_195
OLFML2B TP63 siRNA Immortalized_keratinocyte HaCaT 0.47664 -1.06904 - - DataSet_01_200
OLFML2B HIC1 shRNA Mammary_gland HBL100 1.6063 0.68374 - - DataSet_01_205
OLFML2B MITF shRNA Skin COLO829 1.56249 0.64385 0.51499 0.69598 DataSet_01_207
OLFML2B TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 2.16464 1.11412 0.28479 0.47513 DataSet_01_217
OLFML2B ESR2 siRNA Mammary_gland BT549 0.47085 -1.08667 1.62706e-07 2.30827e-05 DataSet_01_229
OLFML2B MYC siRNA White_adipose_tissue Adipose stem cells 0.64883 -0.62409 3.78346e-06 4e-04 DataSet_01_231
OLFML2B TWIST1 shRNA Stomach CAF32 0.58368 -0.77675 0.00204 0.02479 DataSet_01_253
OLFML2B TWIST1 shRNA Stomach CAF 0.65474 -0.61101 0.05942 0.56128 DataSet_01_254
OLFML2B SIX4 siRNA Ovary PEO1 1.93832 0.9548 0.02171 0.1137 DataSet_01_269
OLFML2B MSX1 siRNA Tooth Dental Pulp Cells 0.36701 -1.44609 1.08704e-05 0.00026 DataSet_01_281
OLFML2B ZIC5 siRNA Skin A375 0.49882 -1.00342 - - DataSet_01_284
OLFML2B JUN siRNA Mammary_gland BT549 0.43112 -1.21383 0.00384 0.02793 DataSet_01_291
OLFML2B POSTN shRNA Brain GSC272 4.07537 2.02693 0.05153 0.53645 DataSet_01_293
OLFML2B TFAP4 siRNA Brain BE(2)-C 0.18791 -2.4119 0.31963 0.51625 DataSet_01_295
OLFML2B PTEN shRNA Skin A431 3.26416 1.70671 0.03394 0.15216 DataSet_01_301
OLFML2B PTEN shRNA Mammary_gland SKBR3 1.7945 0.84358 0.77951 0.93352 DataSet_01_303
OLFML2B ETV5 siRNA Soft_tissue hADSC 1.6316 0.70628 0.00034 0.0106 DataSet_01_304
OLFML2B ARNT siRNA Upper_aerodigestive_tract HSC3 2.64429 1.40288 - - DataSet_01_315
OLFML2B ZNF25 siRNA Bone_marrow hMSC-TERT4 3.85258 1.94582 0.35084 0.81733 DataSet_01_319
OLFML2B KLF7 siRNA Embryo HCE 1.54689 0.62937 0.0575 0.99985 DataSet_01_342
OLFML2B HIF1A siRNA Oral_cavity OEC-M1 1.82198 0.86551 0.19546 0.85151 DataSet_01_348
OLFML2B CDX2 siRNA Colon COLO320 0.53889 -0.89194 - - DataSet_01_357
OLFML2B PAX3 shRNA Soft_tissue Rh30 0.63918 -0.6457 - - DataSet_01_359
OLFML2B RBM17 shRNA Liver HepG2 0.07692 -3.70044 0.02039 0.26816 DataSet_02_100
OLFML2B U2AF2 shRNA Liver HepG2 1.75 0.80735 0.30922 0.4584 DataSet_02_105
OLFML2B SSB shRNA Liver HepG2 6 2.58496 0.00748 0.02207 DataSet_02_107
OLFML2B HNRNPUL1 shRNA Liver HepG2 0.4 -1.32193 0.04522 0.09916 DataSet_02_109
OLFML2B GTF2F1 shRNA Liver HepG2 4 2 0.27976 0.60891 DataSet_02_110
OLFML2B RBM39 shRNA Liver HepG2 0.38462 -1.37851 0.01357 0.21151 DataSet_02_111
OLFML2B BCLAF1 shRNA Liver HepG2 0.08 -3.64386 0.15664 0.2629 DataSet_02_112
OLFML2B TARDBP shRNA Liver HepG2 2.82353 1.4975 0.97614 0.99308 DataSet_02_116
OLFML2B RBM34 shRNA Liver HepG2 0.5 -1 1 1 DataSet_02_121
OLFML2B PCBP2 shRNA Liver HepG2 4.25 2.08746 0.00075 0.04878 DataSet_02_123
OLFML2B FUS shRNA Liver HepG2 5 2.32193 0.07617 0.21895 DataSet_02_124
OLFML2B HNRNPLL shRNA Liver HepG2 0.17647 -2.5025 0.04663 0.09142 DataSet_02_125
OLFML2B SNRNP70 shRNA Liver HepG2 0.05882 -4.08746 0.07467 0.15714 DataSet_02_126
OLFML2B SRSF3 shRNA Liver HepG2 0.52941 -0.91754 0.38746 0.54375 DataSet_02_127
OLFML2B PRPF4 shRNA Liver HepG2 0.14286 -2.80735 0.01564 0.06657 DataSet_02_128
OLFML2B DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.01412 0.51061 DataSet_02_145
OLFML2B CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.85078 0.96549 DataSet_02_146
OLFML2B NONO shRNA Haematopoietic_and_lymphoid_tissue K562 4.66667 2.22239 0.67476 0.80602 DataSet_02_149
OLFML2B SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.05985 0.48872 DataSet_02_150
OLFML2B ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 32 5 0.00096 0.23369 DataSet_02_152
OLFML2B HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.04891 0.51515 DataSet_02_156
OLFML2B HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.16914 0.34551 DataSet_02_160
OLFML2B CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.10476 1 DataSet_02_185
OLFML2B RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 9.33333 3.22239 0.52122 1 DataSet_02_190
OLFML2B AR siRNA Prostate LNCaP 0.528662 -0.919581 0.158849326958394 1 DataSet_03_005
OLFML2B ASCL1 siRNA Lung DMS79 3.55319 1.82912 0.135119347312427 0.802584126635319 DataSet_03_016
OLFML2B ESR1 siRNA Mammary_gland MCF7 0.634484 -0.656344 0.000192026716615108 0.0068822137185206 DataSet_03_071
OLFML2B GATA2 siRNA Uterus Decidual stromal cells 0.495448 -1.0132 0.174659604939168 0.792802948912537 DataSet_03_100
OLFML2B GATA4 siRNA Stomach AGS 4.6549 2.21875 0.0123263498039562 0.497246461975969 DataSet_03_105
OLFML2B GATA6 siRNA Stomach AGS 2.41495 1.27199 0.130642475715814 0.626453235523905 DataSet_03_108
OLFML2B GATA6 siRNA Stomach KatoIII 2.05346 1.03805 0.137821461214913 0.661018405381243 DataSet_03_109
OLFML2B GATA6 siRNA Stomach YCC3 0.569856 -0.81133 0.458041192086003 0.89558779950337 DataSet_03_110
OLFML2B HIC1 CRISPR Prostate PC3 1.60742 0.684746 - - DataSet_03_118
OLFML2B HNF4a siRNA Liver HepG2 0.533333 -0.906891 0.186990177701918 0.791600507558428 DataSet_03_126
OLFML2B IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 3.76329 1.912 0.304967742446036 0.999948959532916 DataSet_03_134
OLFML2B KLF5 siRNA Stomach AGS 1.81328 0.858606 0.428218480370661 0.812782189130839 DataSet_03_149
OLFML2B KLF5 siRNA Stomach YCC3 0.242564 -2.04357 0.0813972516989927 0.404593960504778 DataSet_03_151
OLFML2B MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.35233 -1.505 0.000283397620337191 0.279831662879245 DataSet_03_155
OLFML2B MYB siRNA Cord_Blood CD34+ progenitor cells 1.85055 0.887954 - - DataSet_03_170
OLFML2B MYC siRNA Central_nervous_system DAOY M2.1 2.17411 1.12043 2.95200825780963e-06 1.86318096248521e-05 DataSet_03_178
OLFML2B PHB shRNA Embryo Embryonic stem cells (ESCs) 0.524288 -0.93157 0.00376019705377386 0.0148833974044001 DataSet_03_211
OLFML2B PRRX1 CRISPR Neuroblastoma 691-MES 0.327961 -1.6084 0.0224205009872178 0.89189998148014 DataSet_03_217
OLFML2B SOX11 siRNA Lung_fibroblast NHLF 0.649875 -0.621766 0.247887730929437 0.612273876569061 DataSet_03_237
OLFML2B SOX11 siRNA Lung_fibroblast NHLF 0.64567 -0.631132 0.205284317856525 0.576463585029692 DataSet_03_238
OLFML2B SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.302632 -1.72437 - - DataSet_03_246
OLFML2B STAT3 CRISPR Embryo hESC 0.363143 -1.46139 0.0961009526229174 0.181952339365709 DataSet_03_258
OLFML2B TBX3 siRNA Skin Fibroblast 0.571782 -0.806463 5.06583213487204e-06 0.000587515439840503 DataSet_03_265
OLFML2B ZHX2 shRNA Kidney 786-O 0.520459 -0.942142 0.00111578221769477 0.0162234239571416 DataSet_03_287
OLFML2B ZNF165 siRNA Mammary_gland WHIM12 0.652879 -0.615112 0.72087903811838 0.999997668745677 DataSet_03_289
OLFML2B CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4.75 2.24793 0.105504392945834 0.208841285848378 DataSet_04_002
OLFML2B SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.424242 -1.23704 0.0177043169646353 0.0997114864176297 DataSet_04_018
OLFML2B SMAD4 CRISPR Liver HepG2 1.66667 0.736966 0.338162057090513 0.493182440136185 DataSet_04_035
OLFML2B PAN2 CRISPR Liver HepG2 1.66667 0.736966 0.588061653376827 0.746222005960651 DataSet_04_066
OLFML2B CALR shRNA Liver HepG2 2.25 1.16992 0.637276235173982 0.761988972722034 DataSet_04_053
OLFML2B CCAR1 shRNA Liver HepG2 1.77778 0.830075 0.598970489293038 0.742225304620363 DataSet_04_054
OLFML2B DDX1 shRNA Liver HepG2 1.6 0.678072 0.80042242246976 0.91183764380047 DataSet_04_057
OLFML2B NPM1 shRNA Liver HepG2 0.0769231 -3.70044 0.552856944553698 0.883172355892037 DataSet_04_058
OLFML2B UBE2L3 shRNA Liver HepG2 3 1.58496 0.474608516219321 0.631067966464186 DataSet_04_055
OLFML2B DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.442348779311593 0.855581828731657 DataSet_04_047
OLFML2B DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.400145472788447 0.753555080510603 DataSet_04_050
OLFML2B NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.71129927608641 0.847083204235858 DataSet_04_046
OLFML2B RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0526316 -4.24793 0.267490726832424 0.748208767036091 DataSet_04_076
OLFML2B SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 7 2.80735 0.557050718315245 1 DataSet_04_077
OLFML2B SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.702721058185851 0.923058490273404 DataSet_04_073
OLFML2B SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.781507518032063 0.942598116818686 DataSet_04_075
OLFML2B HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 12 3.58496 0.196434509659411 0.594187938757129 DataSet_02_75
OLFML2B HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.52381 0.607683 0.745233418731581 0.944729462749887 DataSet_02_45
OLFML2B LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.142857 -2.80735 0.297130235985418 0.47247676210609 DataSet_02_35
OLFML2B SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.778000546538685 0.967099802762899 DataSet_02_49
OLFML2B TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.142857 -2.80735 0.303994096574199 0.491248622113946 DataSet_02_43
OLFML2B TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.380952 -1.39232 0.448107427427228 0.609164296231276 DataSet_02_33
OLFML2B TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.238095 -2.07039 0.319975659304009 0.490253193452425 DataSet_02_53
OLFML2B CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 18 4.16993 0.229394478043364 0.421530913006512 DataSet_04_061
OLFML2B ELF3 CRISPR Bile_duct HBDEC2 0.540029 -0.888892 9.903793e-05 1.209029e-03 DataSet_03_304
OLFML2B BRCA1 siRNA Mammary_gland MCF7 0.522738 -0.93584 8.583710e-02 0.9999931 DataSet_03_308
OLFML2B EZH2 shRNA Mammary_gland LM2 0.47371 -1.07792 7.161811e-02 3.810500e-01 DataSet_03_350
OLFML2B SKI CRISPR Blood HL60 0.4 -1.32193 4.253904e-01 0.688047333 DataSet_03_351
OLFML2B ETV5 knockdown Colon HT29 8.47619 3.08342 1.216347e-02 0.127136844 DataSet_03_353
OLFML2B CREBBP CRISPR Brain U5-NPC 1.62538 0.700773 0.6590030473 0.7825506 DataSet_03_356
OLFML2B TP53 knockout Stomach SNU1 3.06328 1.61508 0.0281396002 0.9301241 DataSet_03_365
OLFML2B ZNF148 shRNA Mammary_gland MDA-MB-231 0.430011 -1.21755 6.903679e-03 0.060993263 DataSet_03_366
OLFML2B ZFP36L1 siRNA Urinary_bladder J82 2.08333 1.05889 - - DataSet_03_371
OLFML2B HNRNPU siRNA Colon RKO 0.491628 -1.02436 - - DataSet_03_374
OLFML2B GLI1 siRNA Skeletal_muscle RMS13 2.83441 1.50305 3.788133e-05 0.004794926 DataSet_03_375
OLFML2B SMARCA2 shRNA Lung NCI-H1944 2.37662 1.24891 7.888574e-02 4.502244e-01 DataSet_03_377
OLFML2B EZH2 CRISPR Ovary SKOV3 5.62222 2.49114 8.274579e-05 0.0049463329 DataSet_03_378
OLFML2B DNMT1 siRNA Skin Human melanoma cells 1.67371 0.743052 2.588589e-04 1.092141e-03 DataSet_03_382
OLFML2B TCF19 CRISPR Oral_squamous CAL27 2.06662 1.04727 2.134402e-03 0.0294399211 DataSet_03_383
OLFML2B YY1 shRNA Brain GSC1517 6 2.58496 - - DataSet_03_384
OLFML2B KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.83147 0.873 0.7490479012 0.9534862 DataSet_03_387
OLFML2B TRIM8 siRNA Mammary_gland MCF7 0.169811 -2.558 1.175417e-01 0.2806318527 DataSet_03_388
OLFML2B NFKBIA shRNA Bone_marrow U2OS 0.254841 -1.97233 1.863668e-01 0.87005461 DataSet_03_389
OLFML2B ILF2 siRNA Stomach SGC-7901 0.5 -1 0.5813092085 0.66041517 DataSet_03_393
OLFML2B ASXL1 CRISPR Embryo iPSC 0.530207 -0.915373 0.4322417865 0.8513986 DataSet_03_394
OLFML2B HMGA1 shRNA Bile_duct HUCCT1 4.81395 2.26722 1.722255e-03 0.050028406 DataSet_03_400
OLFML2B JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.69329 0.759833 1.437754e-02 0.3239928 DataSet_03_403
OLFML2B CDK7 shRNA Bone_marrow D458 107.429 6.74723 1.294528e-03 0.08073427 DataSet_03_404
OLFML2B CHD1 shRNA Prostate LNCaP 0.38 -1.39593 3.635772e-01 8.457503e-01 DataSet_03_407
OLFML2B MAP3K7 shRNA Prostate LNCaP 0.48 -1.05889 6.457441e-01 8.074491e-01 DataSet_03_408
OLFML2B STRAP knockout Nerve SK-N-AS 0.26918 -1.89336 - - DataSet_03_409
OLFML2B ZKSCAN3 CRISPR Colon HCT116 0.59021 -0.7607 3.327105e-02 0.360712766 DataSet_03_415
OLFML2B NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2 1 1.750179e-01 0.359427756 DataSet_03_418
OLFML2B FOXQ1 CRISPR Lymph Primary CD4+ T cells 1.77273 0.825971 - - DataSet_03_422
OLFML2B STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 2.0876 1.06184 0.2320119542 1 DataSet_03_430
OLFML2B USP7 shRNA Skin xenograft cells 0.519519 -0.944753 0.30389380 0.4471890 DataSet_03_431
OLFML2B EP300 knockout Pancreas HPAF-II orthotopic cells 0.645652 -0.631171 7.522482e-01 8.588723e-01 DataSet_03_436
OLFML2B SUFU shRNA Mammary_gland HCC1954 cells 0.625 -0.678072 0.9566529866 1.0000000 DataSet_03_437
OLFML2B FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.277533 -1.84927 8.081077e-01 1.00000000 DataSet_03_439
OLFML2B SETDB1 shRNA Colon HCT116 0.439903 -1.18474 - - DataSet_03_440
OLFML2B DAXX shRNA Mammary_gland MDA-MB-231 0.0416354 -4.58605 1.275449e-03 0.05377038 DataSet_03_441
OLFML2B HMG20A siRNA Mammary_gland MDA-MB-231 2.46842 1.30359 0.0012919073 0.1152070 DataSet_03_442
OLFML2B PURA siRNA Cervix HeLa 2.66667 1.41504 4.520945e-02 0.195016342 DataSet_03_444
OLFML2B FOSL1 siRNA Prostate MSKPCa3 0.555556 -0.847997 0.4640164189 0.6715527 DataSet_03_445
OLFML2B CBX2 siRNA Mammary_gland MCF7 0.259158 -1.9481 6.656931e-03 0.0222721900 DataSet_03_451
OLFML2B OGT siRNA Embryo BeWo cells 1.61111 0.688056 1.056783e-01 0.62151935 DataSet_03_453
OLFML2B SMARCA2 shRNA Lung HCC2302 0.117239 -3.09248 3.990468e-13 7.741037e-12 DataSet_03_455
OLFML2B SREBF2 siRNA Umbilical_vein HUVEC 0.480821 -1.05643 9.881163e-03 1.572276e-01 DataSet_03_457
OLFML2B ARID1A shRNA Bile_duct MMNK1 1.58564 0.665064 7.246114e-02 0.284855822 DataSet_03_458
OLFML2B STAT3 shRNA Liver HepG2 3.58333 1.8413 1.330241e-03 0.0486680933 DataSet_03_465
OLFML2B SMARCA1 Cas13 Embryo_kidney HEK293T 0.467532 -1.09686 - - DataSet_03_466
OLFML2B CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.75 1.90689 0.4879895 0.9443437 DataSet_04_071
OLFML2B CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4.75 2.24793 0.2616916 0.417114663 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate CDK7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of OLFML2B
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines