Gene Overview
Target Gene: Pf4
NCBI Official Symbol: Pf4
Entrez ID: 56744
Ensembl ID: ENSMUSG00000029373
Gene Full Name: platelet factor 4
Strand: +
Gene Locus: 5|5 E1
External Links:

Pf4 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate Pf4   
T(co)Fs that Repress Pf4
The Intensity of the Gene Regulated by T(co)Fs:
Pf4-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
Pf4 Adnp knockout Embryo Whole embryonic body 0.266 -1.9105 0.0350397264757779 0.38614908701105 DataSet_11_001
Pf4 Arid1a knockout Liver Liver 1.50171 0.586603 0.720766814564526 0.999999999999956 DataSet_11_004
Pf4 Cbx2 knockout Gonads Embryonic gonads 0.39531 -1.33894 2.66817223531712e-05 0.000478659440158545 DataSet_11_018
Pf4 Elf5 knockout Mammary_gland Mammary gland 2.11969 1.08386 0.0204176807677263 0.246408522822816 DataSet_11_035
Pf4 Gfi1 knockout Macrophage_cells RAW264.7 0.3314 -1.59336 0.00243885872885655 0.00967545726393336 DataSet_11_052
Pf4 Gfi1b knockout Bone_marrow Ter119 positive erythroid cells 62.4526 5.96469 - - DataSet_11_054
Pf4 Hsf4 knockout Eye Lens 0.660711 -0.597909 0.53312378552781 0.987999303842427 DataSet_11_058
Pf4 Lhx8 knockout Ovary Ovary 2.74672 1.45771 0.000457229817246575 0.0138710293379004 DataSet_11_070
Pf4 Mbd1 siRNA Adipose_tissue 3T3-L1 cells 1.63522 0.709485 - - DataSet_11_074
Pf4 Meis1 knockout Bone_marrow Immortalized myeloid cell 14.3314 3.84111 1.91282950778315e-15 5.6513181500662e-12 DataSet_11_082
Pf4 Neurod1 knockout Eye Retina 1.61118 0.688117 0.0348215800427289 0.129991791156631 DataSet_11_088
Pf4 Neurod1 knockout Eye Pineal gland 1.72186 0.783964 0.0567697517844871 0.9983937273602 DataSet_11_089
Pf4 Nhlh2 knockout Eye Retina 0.181592 -2.46123 0.0288723953176726 0.523726874680013 DataSet_11_092
Pf4 Nr2f2 knockout Ovary E16.5 Ovary 2.15656 1.10873 0.114342520708533 0.507180971346382 DataSet_11_095
Pf4 Pbx1 knockout Bone_marrow BM cells 0.295728 -1.75766 0.0866016465644785 0.551762447592729 DataSet_11_102
Pf4 Pitx2 knockout Eye Cornea 0.304463 -1.71566 0.215408252570426 0.605695040970739 DataSet_11_103
Pf4 Pparg siRNA Adipose_tissue Preadipocytes 1.96881 0.977322 0.602168494197432 0.999962577291099 DataSet_11_105
Pf4 Prdm2 shRNA Muscle C2C12 1.65517 0.72698 0.0373079718087586 0.761041192303511 DataSet_11_108
Pf4 Rest knockout Brain Brain 2.19319 1.13303 0.0980681111738533 1 DataSet_11_113
Pf4 Runx1 knockout Embryo Embryo 0.0391075 -4.67641 0.0642415098056345 0.999961610631375 DataSet_11_114
Pf4 Runx1 knockout Lymph ProB cells 1.70074 0.766162 0.0125874628224492 0.0974567550545259 DataSet_11_116
Pf4 Sall1 knockout Kidney Kidney 1.53826 0.6213 0.0334658714710655 0.714146368285326 DataSet_11_122
Pf4 Sall4 shRNA Embryo ES cells 1.82222 0.865699 0.0251665815049963 0.761439970721481 DataSet_11_123
Pf4 Smad4 siRNA Brain bEnd3 0.131035 -2.93198 - - DataSet_11_127
Pf4 Smad4 knockout Aorta Aortic arteries 2.48539 1.31347 0.0197596318503408 0.216614441970358 DataSet_11_128
Pf4 Snai1 knockout Embryo Embryoid body 0.0387475 -4.68975 - - DataSet_11_129
Pf4 Sox11 knockout Eye Retina 1.89888 0.925146 - - DataSet_11_137
Pf4 Srf knockout Aorta Aorta 2.03144 1.0225 0.0484254622908927 0.993526315825099 DataSet_11_148
Pf4 Stat3 knockout Lung Lung typeII cells 1.54599 0.628528 0.0473910656105795 0.668665368591177 DataSet_11_151
Pf4 Tbx1 knockout Ear Otic vesicles 1.55127 0.633449 0.171805970536436 0.996209135879357 DataSet_11_154
Pf4 Tet2 knockout Kidney Kidney 2.38911 1.25647 0.145388895303476 1 DataSet_11_159
Pf4 Tet2 shRNA Macrophage_cells HAFTL 0.463021 -1.11085 0.00947739933189289 0.999974559958775 DataSet_11_160
Pf4 Vdr knockout Bone_marrow Bone marrow-derived macrophages 1.72961 0.79045 0.280560549496992 0.999827445128963 DataSet_11_174
Pf4 Yy1 knockout Muscle Skeletal muscle 1.80035 0.848274 0.000218846186492787 0.00181208535486689 DataSet_11_182
Pf4 Dnmt1 siRNA Pituitary_gland AtT-20 1.61176 0.688638 9.610901e-01 0.9999923 DataSet_11_187
Pf4 Hipk2 knockout Heart cardiac tissue 0.628312 -0.670448 1.814498e-03 7.184781e-02 DataSet_11_238
Pf4 Dnmt1 shRNA Embryo Embryonic fibroblasts 3.14493 1.65303 - - DataSet_11_196
Pf4 Ezh2 knockout Bone_marrow CD45.2+LSK cells 0.0000027005 -18.4983 - - DataSet_11_220
Pf4 Brca1 knockout Brain mouse P7 cortex 1.78395 0.835077 7.019442e-04 2.596085e-02 DataSet_11_203
Pf4 Dnmt3a knockout Skeletal_muscle Satellite cells 0.4 -1.32193 6.364572e-02 1.0000000 DataSet_11_208
Pf4 Lin28a knockout Heart Heart 0.594212 -0.750949 0.1728584479 0.8777652 DataSet_11_243
Pf4 Twist1 knockout Bone_marrow stromal cells 2.14707 1.10237 - - DataSet_11_244
Pf4 Kat6a knockout Embryo Embryonic fibroblasts 0.0986395 -3.34169 4.403904e-05 0.0055988296 DataSet_11_245
Pf4 Fubp1 shRNA Brain brain neural progenitors 15.74 3.97637 0.1868147702 1 DataSet_11_246
Pf4 Eed knockout Brain Forebrain 1.56461 0.645801 4.414996e-02 4.982214e-01 DataSet_11_258
Pf4 Eed knockout Brain hindbrain 1.70016 0.765674 3.720268e-02 6.808905e-01 DataSet_11_259
Pf4 Eed knockout Brain midbrain 1.59508 0.673628 1.599037e-02 4.378768e-01 DataSet_11_260
Pf4 Myc CRISPR Skeletal_muscle muscle stem cells 1.87125 0.904003 4.069097e-01 0.81440395 DataSet_11_272
Pf4 Lin28b knockout Bone_marrow Bone marrow immature B cells 0.352941 -1.5025 4.391650e-01 0.9643594 DataSet_11_274
Pf4 Myod1 CRISPR Skeletal_muscle myoblast 0.173526 -2.52678 2.365425e-03 1.003739e-02 DataSet_11_275
Pf4 Pdx1 CRISPR Liver Liver 0.427481 -1.22607 2.219275e-02 0.320198855 DataSet_11_286
Pf4 Usp7 siRNA Embryo ES cells 0.5 -1 6.264997e-01 0.7767490 DataSet_11_287
Pf4 Kmt2d CRISPR Liver MA1L 4.32387 2.11232 2.631384e-01 5.452595e-01 DataSet_11_290
Pf4 Kmt2d CRISPR Liver MA1L 4.41956 2.1439 2.579286e-01 5.267618e-01 DataSet_11_291
Pf4 Irf8 knockout Brain mice brain 3.30571 1.72496 1.756493e-01 7.222817e-01 DataSet_11_292
Pf4 Mkl1 knockout Bone_marrow Bone marrow differentiated macrophages 0.556579 -0.845341 5.192925e-01 0.7473262488 DataSet_11_294
Pf4 Hmg20a siRNA Hypothalamus Primary hypothalamic astrocytes 1.67284 0.742299 0.1987015213 0.4510700 DataSet_11_300
Pf4 Arid2 knockout Muscle LSK 0.524198 -0.931816 8.178439e-02 9.066623e-01 DataSet_11_301
Pf4 Dnmt1 knockout Skin Keratinocytes 7.55121 2.91671 1.761771e-01 0.5633330942 DataSet_11_303
Pf4 Myc CRISPR Skeletal_muscle quiescent muscle stem cell 46.102 5.52676 3.682487e-01 0.80359421 DataSet_11_310
Pf4 Suz12 knockout Lung Alveolar macrophage 2.91556 1.54377 2.408491e-02 0.2496899922 DataSet_11_311
Pf4 Ahr knockout Liver Liver 0.609756 -0.713696 2.020551e-02 0.3245111952 DataSet_11_315
Pf4 Arid2 knockout Bone_marrow bone marrow leukemia cells 2.77778 1.47393 1.042750e-01 0.7021662 DataSet_11_318
Pf4 Kat7 knockout Thymic_lobes Thymic epithelial cells 0.265306 -1.91427 1.017726e-01 4.225234e-01 DataSet_11_319
Pf4 Bud31 knockout Testis Spermatogonial stem cells 2.83333 1.5025 9.562231e-01 0.9914197 DataSet_11_321
Pf4 Ezh2 knockout Eye Retina 3.79118 1.92265 0.4187394741 1.0000000 DataSet_11_334
Pf4 Gtf2ird1 knockout Lip Lip 0.525488 -0.928271 3.143405e-02 3.348810e-01 DataSet_11_339
Pf4 Dnmt1 siRNA Heart embryonic cardiomyocytes 0.3 -1.73697 5.529269e-03 0.016791118 DataSet_11_340
Pf4 Ezh2 knockout Small_intestinal_crypts small intestinal crypts 0.00242718 -8.6865 0.0810011988 0.1712697 DataSet_11_341
Regulation Region
 
T(co)Fs that significantly regulate Snai1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of Pf4
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)