Gene Overview
| Target Gene: | Rgs5 |
| NCBI Official Symbol: | Rgs5 |
| Entrez ID: | 19737 |
| Ensembl ID: | ENSMUSG00000026678 |
| Gene Full Name: | regulator of G-protein signaling 5 |
| Strand: | + |
| Gene Locus: | 1 H2.3|1 76.84 cM |
| External Links: |
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Rgs5 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Rgs5
T(co)Fs
that Repress Rgs5
The Intensity of the Gene Regulated by T(co)Fs:
Rgs5-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Rgs5 | Atf3 | knockout | Mammary_gland | Breast tumor-associated macrophage | 0.617452 | -0.695601 | 0.927197025612401 | 1 | DataSet_11_006 |
| Rgs5 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.536978 | -0.897066 | 0.0296420124480266 | 0.335043585931618 | DataSet_11_014 |
| Rgs5 | Cebpb | shRNA | Mammary_gland | 4T1 mammary tumor cells | 1.73326 | 0.793484 | 0.231552028048774 | 0.999984070881864 | DataSet_11_022 |
| Rgs5 | Gata2 | knockout | Kidney | renal collecting duct cells | 0.482077 | -1.05266 | - | - | DataSet_11_047 |
| Rgs5 | Lhx8 | knockout | Gonads | Oocytes | 0.452484 | -1.14406 | 0.411051408913965 | 0.993830266659981 | DataSet_11_069 |
| Rgs5 | Mafg | knockout | Embryo | Whole embryo | 0.597416 | -0.743192 | 0.389084572848698 | 1 | DataSet_11_073 |
| Rgs5 | Nhlh2 | knockout | Eye | Retina | 0.381463 | -1.39038 | 0.0880481978451543 | 0.523726874680013 | DataSet_11_092 |
| Rgs5 | Nrf1 | knockdown | Liver | Liver | 2.1665 | 1.11536 | 0.0267097094129728 | 0.0781297184493695 | DataSet_11_096 |
| Rgs5 | Pitx2 | knockout | Eye | Cornea | 1.72091 | 0.783176 | 0.189263193678964 | 0.575443325162396 | DataSet_11_103 |
| Rgs5 | Prdm2 | shRNA | Muscle | C2C12 | 2.78256 | 1.47641 | 0.821484878887607 | 0.999550069809472 | DataSet_11_108 |
| Rgs5 | Prox1 | knockout | Liver | Liver | 3.72746 | 1.89819 | - | - | DataSet_11_109 |
| Rgs5 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.549221 | -0.864542 | 0.0383764130509384 | 0.999784944667092 | DataSet_11_117 |
| Rgs5 | Smad4 | siRNA | Brain | bEnd3 | 1.52576 | 0.60953 | - | - | DataSet_11_127 |
| Rgs5 | Smad4 | knockout | Aorta | Aortic arteries | 0.405922 | -1.30072 | 0.0383849934329433 | 0.300277339401387 | DataSet_11_128 |
| Rgs5 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 0.290908 | -1.78137 | 0.00525764401666279 | 0.999994003527217 | DataSet_11_132 |
| Rgs5 | Sox11 | knockout | Eye | Retina | 1.78132 | 0.832948 | - | - | DataSet_11_137 |
| Rgs5 | Sox9 | knockout | Lung | Trachea | 0.467744 | -1.09621 | 0.00404289387510516 | 0.0862864982531277 | DataSet_11_144 |
| Rgs5 | Sp3 | knockout | Heart | Heart | 1.67243 | 0.741941 | 0.16207689901118 | 0.769319272602354 | DataSet_11_145 |
| Rgs5 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 1.82239 | 0.865831 | 0.0612559467271934 | 0.812330507586414 | DataSet_11_152 |
| Rgs5 | Yy1 | knockout | Muscle | Skeletal muscle | 0.460553 | -1.11856 | 1.54578956745393e-07 | 4.07070732351568e-05 | DataSet_11_182 |
| Rgs5 | Pogz | knockdown | Liver | fetal liver | 0.561836 | -0.83178 | 3.803687e-01 | 0.6498208 | DataSet_11_188 |
| Rgs5 | Cpeb1 | siRNA | Neuron | Neuro-2a | 1.76132 | 0.816656 | - | - | DataSet_11_189 |
| Rgs5 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 0.227257 | -2.1376 | 5.999655e-07 | 1.608139e-05 | DataSet_11_236 |
| Rgs5 | Tet1 | knockout | Embryo | ES cells | 1.55484 | 0.636762 | 1.831330e-01 | 0.41327597 | DataSet_11_216 |
| Rgs5 | Ezh1 | knockout | Muscle | LSK | 1.8025 | 0.85 | 0.0152717200 | 0.07204012 | DataSet_11_233 |
| Rgs5 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 28.7269 | 4.84433 | - | - | DataSet_11_196 |
| Rgs5 | Ezh2 | knockdown | Brain | Brain | 3.93256 | 1.97547 | 3.620097e-05 | 0.0051071670 | DataSet_11_221 |
| Rgs5 | Bptf | shRNA | Mammary_gland | 4T1 cells | 0.662045 | -0.595 | 4.267861e-03 | 0.161151832 | DataSet_11_223 |
| Rgs5 | Smarca4 | shRNA | Embryo | ES cells | 2.23279 | 1.15884 | - | - | DataSet_11_224 |
| Rgs5 | Smarca4 | shRNA | Embryo | ES cells | 2.23279 | 1.15884 | - | - | DataSet_11_225 |
| Rgs5 | Dux | siRNA | Embryo | ES cells | 3.42857 | 1.77761 | 1.188596e-02 | 0.6206523275 | DataSet_11_239 |
| Rgs5 | Ncl | siRNA | Embryo | ES cells | 2.51429 | 1.33015 | 1.198796e-02 | 0.2460989267 | DataSet_11_240 |
| Rgs5 | Dnmt3a | siRNA | Embryo | iPSC | 0.504347 | -0.98751 | - | - | DataSet_11_241 |
| Rgs5 | Dnmt3b | siRNA | Embryo | iPSC | 0.300306 | -1.73549 | - | - | DataSet_11_242 |
| Rgs5 | Twist1 | knockout | Bone_marrow | stromal cells | 0.0592452 | -4.07716 | - | - | DataSet_11_244 |
| Rgs5 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 2.62147 | 1.39038 | 8.200961e-02 | 0.3922066405 | DataSet_11_245 |
| Rgs5 | Fubp1 | shRNA | Brain | brain neural progenitors | 1.53435 | 0.617623 | 0.4408642230 | 1 | DataSet_11_246 |
| Rgs5 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 2.63889 | 1.39993 | 2.880487e-02 | 1.022065e-01 | DataSet_11_250 |
| Rgs5 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 1.51335 | 0.597747 | 0.0466785059 | 0.3984006 | DataSet_11_256 |
| Rgs5 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 6.86124 | 2.77847 | 2.406530e-04 | 0.3692828 | DataSet_11_268 |
| Rgs5 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 129020 | 16.9772 | 3.208955e-01 | 0.81420760 | DataSet_11_272 |
| Rgs5 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.624554 | -0.679102 | 7.206795e-01 | 8.218180e-01 | DataSet_11_275 |
| Rgs5 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 2.43333 | 1.28293 | 1.360085e-02 | 1.240234e-01 | DataSet_11_276 |
| Rgs5 | Ssrp1 | CRISPR | Embryo | ES cells | 51 | 5.67242 | 7.748164e-04 | 0.3093549 | DataSet_11_278 |
| Rgs5 | Usp7 | knockout | Embryo | ES cells | 44 | 5.45943 | 3.301271e-03 | 0.2150674 | DataSet_11_279 |
| Rgs5 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 2.05529 | 1.03934 | 8.116695e-03 | 0.5570259 | DataSet_11_283 |
| Rgs5 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 2.09929 | 1.0699 | - | - | DataSet_11_285 |
| Rgs5 | Pdx1 | CRISPR | Liver | Liver | 0.551427 | -0.858759 | 8.427613e-02 | 0.397445551 | DataSet_11_286 |
| Rgs5 | Usp7 | siRNA | Embryo | ES cells | 9.8 | 3.29278 | 3.341359e-04 | 0.5386350 | DataSet_11_287 |
| Rgs5 | Kmt2d | CRISPR | Liver | MA1L | 0.542153 | -0.883229 | 6.312417e-07 | 2.517169e-04 | DataSet_11_290 |
| Rgs5 | Kmt2d | CRISPR | Liver | MA1L | 0.554126 | -0.851715 | 9.693680e-07 | 3.865497e-04 | DataSet_11_291 |
| Rgs5 | Ssrp1 | CRISPR | Embryo | ES cells | 3.5 | 1.80736 | 1.837126e-01 | 0.50577329 | DataSet_11_296 |
| Rgs5 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.511966 | -0.965882 | 4.828261e-01 | 0.9999903 | DataSet_11_299 |
| Rgs5 | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 2.25 | 1.16992 | 0.0130481419 | 0.2453370 | DataSet_11_300 |
| Rgs5 | Dnmt1 | knockout | Skin | Keratinocytes | 3.77414 | 1.91615 | 1.449504e-01 | 0.5120957019 | DataSet_11_303 |
| Rgs5 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 2.47826 | 1.30933 | - | - | DataSet_11_308 |
| Rgs5 | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 1.87143 | 0.90414 | 2.541510e-02 | 0.79913034 | DataSet_11_309 |
| Rgs5 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 2.14738 | 1.10258 | 3.465452e-01 | 0.80359421 | DataSet_11_310 |
| Rgs5 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 65.0707 | 6.02394 | - | - | DataSet_11_313 |
| Rgs5 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.0833333 | -3.58496 | 1.939989e-02 | 0.1780465474 | DataSet_11_317 |
| Rgs5 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.263889 | -1.922 | 9.031910e-02 | 0.7021662 | DataSet_11_318 |
| Rgs5 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.357378 | -1.48448 | 1.115335e-04 | 9.437785e-03 | DataSet_11_320 |
| Rgs5 | Gata2 | knockout | Brain | Pituitary gland | 2.39506 | 1.26006 | 0.214292722 | 0.9730581 | DataSet_11_322 |
| Rgs5 | Prmt1 | siRNA | Adipose_tissue | 3T3-L1 cells | 1.51852 | 0.602664 | 4.799627e-02 | 0.9832045 | DataSet_11_325 |
| Rgs5 | Ezh2 | knockout | Eye | Retina | 0.361111 | -1.46949 | 2.038888e-01 | 7.918620e-01 | DataSet_11_333 |
| Rgs5 | Ezh2 | knockout | Eye | Retina | 50.5802 | 5.6605 | 0.1282238534 | 1.0000000 | DataSet_11_334 |
| Rgs5 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 1.65689 | 0.728479 | 2.196608e-01 | 0.69832724 | DataSet_11_337 |
| Rgs5 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 2.16422 | 1.11385 | 4.412837e-02 | 0.55135465 | DataSet_11_338 |
| Rgs5 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.00635471 | -7.29796 | 0.0047942094 | 0.1712697 | DataSet_11_341 |
| Rgs5 | Hnrnpk | siRNA | Embryo | ES cells | 8.89537 | 3.15305 | 7.670200e-03 | 0.022749891 | DataSet_11_342 |
| Rgs5 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 1.87143 | 0.90414 | 2.541510e-02 | 0.79913034 | DataSet_11_347 |
Regulation Region
Expression Atlas of Rgs5