Gene Overview
Target Gene: SCG2
NCBI Official Symbol: SCG2
Entrez ID: 7857
Ensembl ID: ENSG00000171951
Gene Full Name: secretogranin II
Strand: -
Gene Locus: 2q36.1
External Links:

SCG2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate SCG2   
T(co)Fs that Repress SCG2
The Intensity of the Gene Regulated by T(co)Fs:
SCG2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
SCG2 FOXA1 shRNA Prostate 22RV1 0.60669 -0.72096 - - DataSet_01_105
SCG2 FOXO1 shRNA Bone EWS-FLI1 1.97935 0.98503 0.00685 0.14995 DataSet_01_106
SCG2 ARID1A shRNA Ovary OSE4 0.44801 -1.1584 - - DataSet_01_108
SCG2 HOXA1 siRNA Lung_fibroblast IMR-90 7.20395 2.84879 6.34861e-05 0.01014 DataSet_01_110
SCG2 GABPA siRNA Lung A549 4.88563 2.28854 3.45423e-12 2.04725e-09 DataSet_01_113
SCG2 ZIC2 siRNA Pancreas PANC1 6.20531 2.6335 - - DataSet_01_121
SCG2 FOXM1 siRNA Central_nervous_system U87 86.5718 6.43583 - - DataSet_01_122
SCG2 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 1.53533 0.61855 0.00038 0.00731 DataSet_01_127
SCG2 ID1 shRNA Neuroepithelium GSC8 0.65161 -0.61792 2.2316e-08 5.87224e-08 DataSet_01_134
SCG2 REST siRNA Uterus Smooth muscle cells 4.51193 2.17374 0.03621 0.99996 DataSet_01_136
SCG2 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.01566 1.01125 0.08029 0.80735 DataSet_01_137
SCG2 REST siRNA Adrenal_gland H295R/TR 5.16247 2.36806 1.76481e-08 9.03469e-05 DataSet_01_145
SCG2 TEAD4 shRNA Stomach SNU216 1.82975 0.87165 - - DataSet_01_151
SCG2 ZFX shRNA Central_nervous_system DAOY 1.80245 0.84996 0.22361 0.99991 DataSet_01_157
SCG2 ELK1 siRNA Peripheral_blood CD4+ T cells 0.59739 -0.74325 0.32654 0.55078 DataSet_01_162
SCG2 GATA3 siRNA Peripheral_blood CD4+ T cells 0.52658 -0.92529 0.18111 0.51611 DataSet_01_163
SCG2 JUN siRNA Peripheral_blood CD4+ T cells 0.52675 -0.92481 0.18377 0.42125 DataSet_01_164
SCG2 MAF siRNA Peripheral_blood CD4+ T cells 0.57967 -0.78671 0.27959 0.63833 DataSet_01_165
SCG2 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.65516 -0.61009 0.47766 0.74914 DataSet_01_166
SCG2 NFKB1 siRNA Peripheral_blood CD4+ T cells 0.4977 -1.00664 0.13596 0.67398 DataSet_01_167
SCG2 STAT3 siRNA Peripheral_blood CD4+ T cells 0.55487 -0.84977 0.22993 0.99183 DataSet_01_168
SCG2 HOXB7 siRNA Pancreas Capan-1 0.51786 -0.94936 0.03386 0.51663 DataSet_01_170
SCG2 TCF4 siRNA Autonomic_ganglia SH-SY5Y 4.16437 2.0581 0.00012 0.01248 DataSet_01_185
SCG2 CREB1 shRNA Parotid_gland H3118 MEC 2.36332 1.24081 0.8374 0.94317 DataSet_01_194
SCG2 TP63 siRNA Head_and_neck SCC-1 0.6046 -0.72594 - - DataSet_01_198
SCG2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.54886 -0.8655 - - DataSet_01_209
SCG2 LIN28A siRNA Embryo H9 1.74534 0.8035 0.06445 0.16279 DataSet_01_215
SCG2 KLF2 shRNA Bone_marrow RPMI8226 5.14534 2.36327 0.07894 0.68303 DataSet_01_226
SCG2 TWIST1 shRNA Stomach CAF14 2.36873 1.24411 0.0096 0.99996 DataSet_01_252
SCG2 TWIST1 shRNA Stomach CAF 1.52594 0.6097 0.06315 0.56128 DataSet_01_254
SCG2 YBX1 shRNA Mammary_gland MDA 0.49428 -1.0166 3.46563e-09 3.20164e-07 DataSet_01_255
SCG2 YBX1 shRNA Mammary_gland MDA 0.4346 -1.20224 0.00011 0.00202 DataSet_01_257
SCG2 MYT1L shRNA Fetal_spinal_cord SPC04 0.56556 -0.82225 0.0307 0.27581 DataSet_01_264
SCG2 PTEN shRNA Lung A549 2.82451 1.498 2.76134e-12 8.828e-09 DataSet_01_276
SCG2 AR shRNA Prostate CWR22Pc 2.01224 1.0088 0.01283 0.0704 DataSet_01_278
SCG2 STAT5 shRNA Prostate CWR22Pc 3.17508 1.6668 0.00147 0.01877 DataSet_01_279
SCG2 ZIC5 siRNA Skin A375 2.81399 1.49262 - - DataSet_01_284
SCG2 NFYA shRNA Colon HCT1163 0.60933 -0.7147 0.00088 0.01992 DataSet_01_287
SCG2 POSTN shRNA Brain GSC272 0.29224 -1.77479 0.02221 0.49102 DataSet_01_293
SCG2 TFAP4 siRNA Brain BE(2)-C 0.17639 -2.50319 0.28692 0.51625 DataSet_01_295
SCG2 ARID1B shRNA Liver IRM90 3.91184 1.96785 1.04263e-08 5.80075e-05 DataSet_01_298
SCG2 NR2E1 shRNA Neuroepithelium PBT003 2.55841 1.35524 0.2914 0.69177 DataSet_01_306
SCG2 ELK3 shRNA Mammary_gland MDA-MB-231 0.49296 -1.02045 0.00289 0.00806 DataSet_01_318
SCG2 MYC siRNA Colon HCT116 3.98458 1.99443 5.16999e-05 0.00025 DataSet_01_324
SCG2 HOXC6 siRNA Prostate LNCaP 0.18887 -2.40453 0.02618 0.99927 DataSet_01_333
SCG2 GRHL3 siRNA Skin NHEK 0.64293 -0.63727 0.02485 0.40068 DataSet_01_336
SCG2 REST siRNA Skin NHEK 2.55442 1.35299 2.06248e-05 0.00448 DataSet_01_337
SCG2 RBM17 shRNA Liver HepG2 2 1 0.83401 0.92567 DataSet_02_100
SCG2 FIP1L1 shRNA Liver HepG2 0.4 -1.32193 0.00097 0.01448 DataSet_02_103
SCG2 TAF15 shRNA Liver HepG2 3 1.58496 0.0397 0.07495 DataSet_02_106
SCG2 ZNF622 shRNA Liver HepG2 2.85714 1.51457 0.24245 0.31603 DataSet_02_108
SCG2 HNRNPUL1 shRNA Liver HepG2 9 3.16993 0.31383 0.41027 DataSet_02_109
SCG2 RBM39 shRNA Liver HepG2 3.5 1.80735 0.05826 0.26598 DataSet_02_111
SCG2 BCLAF1 shRNA Liver HepG2 4.6 2.20163 0.86048 0.90519 DataSet_02_112
SCG2 XRCC5 shRNA Liver HepG2 3 1.58496 0.0247 0.16796 DataSet_02_114
SCG2 TARDBP shRNA Liver HepG2 0.25 -2 0.70246 0.77082 DataSet_02_116
SCG2 PTBP1 shRNA Liver HepG2 4.66667 2.22239 0.00832 0.02023 DataSet_02_120
SCG2 RBM34 shRNA Liver HepG2 0.5 -1 1 1 DataSet_02_121
SCG2 PCBP2 shRNA Liver HepG2 9 3.16993 0.00338 0.05701 DataSet_02_123
SCG2 FUS shRNA Liver HepG2 4 2 0.00537 0.07176 DataSet_02_124
SCG2 SNRNP70 shRNA Liver HepG2 0.41667 -1.26303 0.40508 0.52265 DataSet_02_126
SCG2 SRSF3 shRNA Liver HepG2 3.91667 1.96963 0.08017 0.20177 DataSet_02_127
SCG2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.00702 0.25699 DataSet_02_129
SCG2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5812 -0.7829 0.09021 0.16809 DataSet_02_131
SCG2 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65054 -0.6203 0.04876 0.17566 DataSet_02_132
SCG2 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.63248 -0.66091 0.02954 0.25248 DataSet_02_133
SCG2 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.13502 0.27669 DataSet_02_135
SCG2 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.04274 1.0305 0.00477 0.14579 DataSet_02_136
SCG2 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.62393 0.69949 0.01582 0.21164 DataSet_02_137
SCG2 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.15094 1.10497 0.59476 0.77104 DataSet_02_140
SCG2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.41379 -1.27302 0.04087 0.08663 DataSet_02_143
SCG2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.51613 -0.9542 0.00229 0.19727 DataSet_02_144
SCG2 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52071 -0.94145 0.00179 0.08322 DataSet_02_147
SCG2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.62222 -0.6845 0.06731 0.2508 DataSet_02_149
SCG2 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65649 0.72813 0.02769 0.28434 DataSet_02_152
SCG2 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.53153 -0.91177 0.02356 0.51515 DataSet_02_156
SCG2 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 0.57738 -0.7924 0.00229 0.11467 DataSet_02_160
SCG2 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.34906 -1.51847 0.01056 0.17801 DataSet_02_166
SCG2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.02005 0.0697 DataSet_02_169
SCG2 ZFX siRNA Prostate C4-2B 1.93548 0.95269 0.02816 0.06772 DataSet_02_172
SCG2 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.65432 0.72624 0.29146 1 DataSet_02_174
SCG2 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 1.8022 0.84976 0.11061 1 DataSet_02_182
SCG2 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.63158 -0.66297 0.46322 1 DataSet_02_187
SCG2 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64744 -0.62719 0.2188 1 DataSet_02_195
SCG2 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.56395 -0.82635 0.22176 1 DataSet_02_199
SCG2 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.6069 0.68428 0.11351 1 DataSet_02_202
SCG2 AR siRNA Prostate LNCaP 3.07092 1.61867 0.0294312542374568 1 DataSet_03_005
SCG2 ASCL1 siRNA Lung DMS79 1.72246 0.784473 0.0652132855647433 0.708755235336452 DataSet_03_016
SCG2 ATF3 knockout Colon HCT116 0.487502 -1.03652 3.56890593788666e-07 0.000687549728933865 DataSet_03_017
SCG2 BCL6 siRNA Lymph Pfeiffer DLBCL 0.255199 -1.97031 0.0564675828614897 0.501149797895721 DataSet_03_026
SCG2 CEBPB siRNA Mammary_gland MCF7 1.69808 0.763909 0.00215098641160134 0.993756826434039 DataSet_03_048
SCG2 CEBPB siRNA Embryo hESC 12.4411 3.63704 0.0026259245630172 0.151701608012047 DataSet_03_049
SCG2 CHEK1 siRNA Mammary_gland MCF7 2.07549 1.05345 0.000362276001846305 0.999587656258211 DataSet_03_053
SCG2 ERF siRNA Mammary_gland MCF7 1.57496 0.655315 0.00471043166171255 0.999855523449227 DataSet_03_067
SCG2 ESR1 siRNA Uterus Endometrial stromal cells 1.80751 0.854 - - DataSet_03_069
SCG2 FOXA1 siRNA Mammary_gland MCF7 2.23425 1.15979 3.01004059028833e-05 0.000918472719784199 DataSet_03_080
SCG2 GATA2 siRNA Uterus Decidual stromal cells 2.06484 1.04603 0.524280558834837 0.939686765565998 DataSet_03_100
SCG2 GATA6 siRNA Stomach AGS 1.73879 0.798081 0.0766715333480693 0.547064875641098 DataSet_03_108
SCG2 GFP siRNA Mammary_gland BT-20 cells 0.625 -0.678072 0.190707456788735 0.762642199972988 DataSet_03_111
SCG2 HINFP siRNA Bone_marrow hTERT-RPE1 3.38915 1.76092 4.95250825955214e-05 0.0236170755114905 DataSet_03_122
SCG2 HMGA1 siRNA Mammary_gland MDA-MB-231 1.52657 0.610296 9.75342676898837e-07 2.59472305506687e-05 DataSet_03_124
SCG2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.74613 0.804165 0.29885433183973 0.999948959532916 DataSet_03_134
SCG2 KLF5 siRNA Stomach KatoIII 1.92184 0.942491 0.000527615051514997 0.075330304772914 DataSet_03_150
SCG2 MAX siRNA Mammary_gland MCF7 1.71124 0.775043 0.00199267283411182 0.999907009675999 DataSet_03_158
SCG2 MEF2D shRNA Liver HuH7 3.3296 1.73535 - - DataSet_03_162
SCG2 MITF siRNA Skin MZ7 2.43684 1.28501 2.51839323808885e-09 8.25053210597304e-08 DataSet_03_165
SCG2 MYB siRNA Cord_Blood CD34+ progenitor cells 1.97739 0.9836 - - DataSet_03_170
SCG2 MYC siRNA Central_nervous_system DAOY M2.1 5.44466 2.44484 4.86119062078565e-08 9.93417526951357e-07 DataSet_03_178
SCG2 MYCN CRISPR Neuroblastoma CHP-134 0.562817 -0.829263 0.00178459140706703 0.0150617448931098 DataSet_03_183
SCG2 MYCN CRISPR Neuroblastoma CHP-134 0.562817 -0.829263 0.00178459140706703 0.0150617448931098 DataSet_03_184
SCG2 MYCN siRNA Brain BE(2)C cells 1.59759 0.6759 - - DataSet_03_187
SCG2 NR4A3 siRNA Pancreas 1.1B4 4.15206 2.05383 2.46007605111857e-05 0.000287369534444004 DataSet_03_203
SCG2 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.18277 1.12616 0.00459230362557677 0.0172449308139077 DataSet_03_211
SCG2 PRRX1 CRISPR Neuroblastoma 691-MES 0.308034 -1.69884 0.152919040025747 0.89189998148014 DataSet_03_217
SCG2 REST siRNA Adrenal_gland H295R/TR 3.79469 1.92398 7.91093141083733e-05 0.0211931124588949 DataSet_03_228
SCG2 SOX11 siRNA Lung_fibroblast NHLF 2.43097 1.28153 0.026561830700194 0.337410974409811 DataSet_03_237
SCG2 SOX11 siRNA Lung_fibroblast NHLF 2.61632 1.38754 0.206533924302867 0.577527278071135 DataSet_03_238
SCG2 SOX2 siRNA Mammary_gland GSC-11 0.649726 -0.622096 5.51925089246073e-05 0.00522707544852998 DataSet_03_245
SCG2 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.296296 -1.75489 - - DataSet_03_246
SCG2 SP1 siRNA Cervix HeLa 0.565773 -0.821705 2.07409028691414e-06 0.000202894215305345 DataSet_03_249
SCG2 SP1 siRNA Mammary_gland MDA-MB-231 0.364015 -1.45793 0.101643801040491 0.413972819854456 DataSet_03_250
SCG2 SP1 siRNA Ovary OVSAYO 0.430726 -1.21516 0.098101039030404 0.381163687508885 DataSet_03_251
SCG2 STAT3 CRISPR Embryo hESC 1.8844 0.914104 0.117774299763677 0.191445035318795 DataSet_03_258
SCG2 STAT6 siRNA Umbilical_vein HUVEC 4.8125 2.26679 0.122431069798582 0.813799411240831 DataSet_03_264
SCG2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.602564 -0.730813 0.339102710845827 0.467770564386349 DataSet_04_002
SCG2 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 4.37234 2.12841 0.844319000767971 0.89880678840137 DataSet_04_014
SCG2 NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57868 -0.789162 0.127993204563124 0.195566478881212 DataSet_04_015
SCG2 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.11304 1.07932 0.00298240179305053 0.0786343354168621 DataSet_04_018
SCG2 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71795 0.780687 0.00269286514293353 0.0979887211869635 DataSet_04_019
SCG2 SMAD4 CRISPR Liver HepG2 2 1 0.140828772420542 0.288858310753861 DataSet_04_035
SCG2 APTX CRISPR Liver HepG2 3 1.58496 0.606675347517942 0.960077219752962 DataSet_04_069
SCG2 DNMT3B CRISPR Liver HepG2 0.571429 -0.807355 0.717083270012874 0.886761893373262 DataSet_04_044
SCG2 PAN2 CRISPR Liver HepG2 2 1 0.547689635690412 0.713862614409128 DataSet_04_066
SCG2 RIOK2 CRISPR Liver HepG2 0.333333 -1.58496 0.882249658541505 1 DataSet_04_070
SCG2 SEPT11 CRISPR Liver HepG2 2 1 0.720327692246195 0.87924718410078 DataSet_04_068
SCG2 CALR shRNA Liver HepG2 2.36364 1.24101 0.223521633631594 0.350872024603157 DataSet_04_053
SCG2 CCAR1 shRNA Liver HepG2 1.66667 0.736966 0.862177358154059 0.932017881290817 DataSet_04_054
SCG2 DDX1 shRNA Liver HepG2 3.5 1.80735 0.694462105429217 0.852719288082108 DataSet_04_057
SCG2 NPM1 shRNA Liver HepG2 0.5 -1 0.950730627066374 0.995448784130025 DataSet_04_058
SCG2 PRPF6 shRNA Liver HepG2 2.5 1.32193 0.632356360064133 0.805490615929857 DataSet_04_056
SCG2 YBX3 shRNA Liver HepG2 2.5 1.32193 0.802603316221644 0.899059094379016 DataSet_02_98
SCG2 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.68235 0.75048 0.124522144541215 0.499450803122077 DataSet_04_050
SCG2 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.04274 1.0305 0.000587601885323167 0.0365970507551275 DataSet_04_046
SCG2 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.66 0.731183 0.241926421077029 0.630992201825976 DataSet_04_073
SCG2 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.82 0.863938 0.0376136026089227 0.102145031590457 DataSet_04_049
SCG2 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.468085 -1.09516 0.176859609993691 0.468907888061324 DataSet_02_32
SCG2 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.404255 -1.30666 0.0736746029344957 0.159968140260342 DataSet_02_47
SCG2 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.90909 1.54057 0.328227169386302 0.728662893571012 DataSet_02_49
SCG2 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.404255 -1.30666 0.0944744526888697 0.216646518789517 DataSet_02_43
SCG2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.0425532 -4.55459 0.0130005831110768 0.0411992536531813 DataSet_02_33
SCG2 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.659574 -0.600393 0.356257868899854 0.527296141085502 DataSet_02_53
SCG2 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.57895 0.658963 0.0123543631566064 0.126295703085554 DataSet_04_062
SCG2 KDM5A shRNA Brain NCH644 2.42923 1.2805 4.883897e-02 0.497183978 DataSet_03_316
SCG2 SMARCA4 siRNA Colon HCT116 2.04036 1.02882 5.148110e-02 7.604388e-01 DataSet_03_301
SCG2 ELF3 knockdown Bile_duct HBDEC2 0.66185 -0.595424 1.471525e-01 2.819334e-01 DataSet_03_305
SCG2 INO80 siRNA Muscle RD 1.70702 0.77148 - - DataSet_03_344
SCG2 AEBP1 siRNA Central_nervous_system U87MG 1.6576 0.729094 6.073886e-01 0.9999434 DataSet_03_338
SCG2 DNMT1 shRNA Lung hTERT-immortalised adult fibroblasts 2.8353 1.5035 5.660890e-03 1.879703e-01 DataSet_03_311
SCG2 ZFX siRNA Prostate C4-2B 1.50521 0.589966 4.897307e-02 8.136067e-02 DataSet_03_348
SCG2 SKI CRISPR Blood HL60 0.0534759 -4.22497 7.467945e-04 0.071532454 DataSet_03_351
SCG2 ETV5 knockdown Colon HT29 0.5 -1 4.049242e-01 0.605926801 DataSet_03_353
SCG2 TET1 CRISPR Mammary_gland Hs578T 0.297455 -1.74926 5.732302e-04 8.728663e-03 DataSet_03_355
SCG2 CREBBP CRISPR Brain U5-NPC 1.69463 0.760969 0.6178130163 0.7615550 DataSet_03_356
SCG2 TP53 CRISPR Brain U5-NPC 4.1568 2.05547 5.269393e-03 1.623145e-01 DataSet_03_358
SCG2 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 0.132881 -2.91179 3.499206e-01 5.927511e-01 DataSet_03_359
SCG2 NCOA2 siRNA Uterus endometrial stromal cells 0.513474 -0.961636 0.7644292206 1 DataSet_03_360
SCG2 MYC siRNA Peripheral_blood T lymphocyte 4.36981 2.12757 3.984360e-01 0.648149121 DataSet_03_363
SCG2 EP300 shRNA Mammary_gland MCF10AT 2.29412 1.19794 1.218951e-02 0.083345902 DataSet_03_364
SCG2 TP53 knockout Stomach SNU1 0.545077 -0.875468 0.5986816721 0.9636875 DataSet_03_365
SCG2 ZNF148 shRNA Mammary_gland MDA-MB-231 4.41622 2.14281 3.973131e-07 0.006378067 DataSet_03_366
SCG2 USP22 shRNA Liver PLC_PRF_5 cells 1.71875 0.78136 2.674113e-02 0.16912822 DataSet_03_368
SCG2 DNMT3A knockout Embryo_kidney HEK293T 1.67536 0.744473 - - DataSet_03_369
SCG2 ZFP36L1 siRNA Urinary_bladder J82 2.33333 1.22239 - - DataSet_03_371
SCG2 BHLHE40 shRNA Cervix HeLaS3 0.519512 -0.94477 2.983148e-01 0.84447131 DataSet_03_372
SCG2 GLI1 siRNA Skeletal_muscle RMS13 10.0822 3.33374 1.030135e-01 0.280411979 DataSet_03_375
SCG2 ZNF213 siRNA Mammary_gland MCF7 0.472239 -1.08241 5.441918e-01 7.550057e-01 DataSet_03_376
SCG2 EZH2 CRISPR Ovary SKOV3 4 2 6.977999e-02 0.2302336924 DataSet_03_378
SCG2 DDX5 shRNA Stomach HGC-27 0.272727 -1.87447 - - DataSet_03_379
SCG2 ZBTB7A siRNA Stomach BGC823 4.33261 2.11524 - - DataSet_03_380
SCG2 DNMT1 siRNA Skin Human melanoma cells 2.43189 1.28208 1.253698e-06 3.281978e-05 DataSet_03_382
SCG2 TCF19 CRISPR Oral_squamous CAL27 0.600404 -0.735994 5.888557e-01 0.8085379522 DataSet_03_383
SCG2 YY1 shRNA Brain GSC1517 3.52529 1.81774 - - DataSet_03_384
SCG2 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.607721 -0.718518 0.4013868350 0.8583205 DataSet_03_387
SCG2 TRIM8 siRNA Mammary_gland MCF7 3.4 1.76553 9.774080e-02 0.2488355656 DataSet_03_388
SCG2 NFKBIA shRNA Bone_marrow U2OS 0.201325 -2.3124 4.133996e-01 0.87005461 DataSet_03_389
SCG2 YY1 knockdown Liver HepG2 7 2.80735 6.522804e-03 2.456687e-02 DataSet_03_390
SCG2 IKZF2 CRISPR Lymph CAR T Cell 4.28265 2.09851 5.228926e-01 0.847824801 DataSet_03_397
SCG2 TLE4 CRISPR Lymph CAR T Cell 0.531406 -0.912114 8.898019e-01 0.97811957 DataSet_03_398
SCG2 RELA CRISPR Brain T30 0.170007 -2.55633 0.0066541451 0.8400824 DataSet_03_399
SCG2 HMGA1 shRNA Bile_duct HUCCT1 4.17512 2.06182 2.595163e-05 0.006655590 DataSet_03_400
SCG2 EHF shRNA Stomach MKN7 0.0586726 -4.09117 - - DataSet_03_402
SCG2 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 2.56667 1.3599 1.541765e-01 0.3606158 DataSet_03_403
SCG2 CDK7 shRNA Bone_marrow D458 2 1 9.291611e-01 0.96895184 DataSet_03_404
SCG2 TFAP2A knockout Embryo H9 8.81818 3.14048 1.081735e-02 0.06770764 DataSet_03_405
SCG2 STRAP knockout Nerve SK-N-AS 1.8498 0.887372 - - DataSet_03_409
SCG2 SIRT1 siRNA Pancreas PANC1 0.377907 -1.4039 3.076642e-02 0.099286863 DataSet_03_410
SCG2 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.423077 -1.24101 1.622293e-01 0.347422939 DataSet_03_418
SCG2 FOXK2 shRNA Ovary OVCAR-5 3.5 1.80736 2.355187e-02 0.12182767 DataSet_03_419
SCG2 MAEL CRISPR Liver Alexander cells 0.377358 -1.40599 - - DataSet_03_423
SCG2 FOXP3 CRISPR Peripheral_blood Naive Treg 0.5 -1 9.448520e-01 0.981202148 DataSet_03_427
SCG2 IKZF2 shRNA Lymph Hut78 2.38568 1.2544 1.254067e-01 0.59573629 DataSet_03_429
SCG2 USP7 shRNA Skin xenograft cells 0.451779 -1.14631 0.26560911 0.4348960 DataSet_03_431
SCG2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.593731 -0.752118 1.350183e-01 0.503025606 DataSet_03_434
SCG2 POU2AF1 CRISPR Lymph SUDHL4 7 2.80735 2.502878e-02 0.076347260 DataSet_03_435
SCG2 EP300 knockout Pancreas HPAF-II orthotopic cells 0.168703 -2.56744 1.195726e-05 4.232369e-04 DataSet_03_436
SCG2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.67347 0.742842 7.608609e-01 0.99568208 DataSet_03_439
SCG2 SETDB1 shRNA Colon HCT116 0.288558 -1.79307 - - DataSet_03_440
SCG2 DAXX shRNA Mammary_gland MDA-MB-231 0.279248 -1.84038 2.550859e-04 0.03507431 DataSet_03_441
SCG2 SMARCA2 shRNA Lung HCC2302 0.0172243 -5.85941 4.310590e-11 4.017812e-10 DataSet_03_455
SCG2 PPARG siRNA Aortic_valve Valvular endothelial cell 14.4042 3.84842 8.972478e-10 4.721766e-06 DataSet_03_456
SCG2 ARID1A shRNA Bile_duct MMNK1 4.37246 2.12844 2.173246e-05 0.006943690 DataSet_03_458
SCG2 TXNIP shRNA Cord_Blood CD34+ cells 0.6 -0.736966 - - DataSet_03_461
SCG2 SOX9 knockout Liver HuH7 1.75 0.807355 6.372635e-01 7.426870e-01 DataSet_03_463
SCG2 PARP1 knockout Embryo_kidney HEK293a 3.76606 1.91305 6.762110e-07 1.028150e-05 DataSet_03_464
SCG2 SMARCA1 Cas13 Embryo_kidney HEK293T 6.75 2.75489 - - DataSet_03_466
SCG2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.375 1.24793 - - DataSet_03_467
SCG2 SMARCA1 shRNA Embryo_kidney HEK293T 2.75 1.45943 - - DataSet_03_468
SCG2 EZH2 siRNA Prostate LNCaP 0.451925 -1.14585 - - DataSet_03_472
SCG2 EZH2 siRNA Prostate LNCaP 15 3.90689 1.995423e-01 1.0000000 DataSet_03_475
SCG2 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.602564 -0.730813 0.3126373 0.472435943 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SOX2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of SCG2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines