Gene Overview
Target Gene: SELL
NCBI Official Symbol: SELL
Entrez ID: 6402
Ensembl ID: ENSG00000188404
Gene Full Name: selectin L
Strand: -
Gene Locus: 1q24.2
External Links:

SELL Significantly Regulated by These T(co)Fs

T(co)Fs that Activate SELL   
T(co)Fs that Repress SELL
The Intensity of the Gene Regulated by T(co)Fs:
SELL-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
SELL HNF1B shRNA Ovary RMG2 1.59941 0.67754 0.02641 0.05592 DataSet_01_103
SELL ZIC2 siRNA Pancreas PANC1 1.59629 0.67472 - - DataSet_01_121
SELL ZNF665 siRNA Gastrointestinal_tissue GIST-T1 1.58696 0.66626 0.00024 0.00689 DataSet_01_129
SELL EGR4 siRNA Lung SBC-5 2.79067 1.48061 0.08945 0.43881 DataSet_01_132
SELL IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.2009 1.1381 0.03451 0.56877 DataSet_01_137
SELL ZFX shRNA Haematopoietic_and_lymphoid_tissue NOMO-1 2.97874 1.5747 0.38647 0.99999 DataSet_01_144
SELL STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.264 -1.92137 7.80409e-06 0.00535 DataSet_01_154
SELL HSF1 shRNA Skin A375 0.51264 -0.964 0.01626 0.09118 DataSet_01_155
SELL RUNX1 siRNA Haematopoietic_and_lymphoid_tissue Kasumi-1 1.55679 0.63858 7.37444e-06 0.00137 DataSet_01_159
SELL ELK1 siRNA Peripheral_blood CD4+ T cells 3.2518 1.70124 0.16399 0.34478 DataSet_01_162
SELL JUN siRNA Peripheral_blood CD4+ T cells 2.84195 1.50688 0.17888 0.41324 DataSet_01_164
SELL NFATC3 siRNA Peripheral_blood CD4+ T cells 3.14957 1.65515 0.17209 0.44306 DataSet_01_166
SELL HOXB7 siRNA Pancreas MIA PaCa-2 1.73189 0.79235 0.23228 0.68671 DataSet_01_169
SELL HOXB7 siRNA Pancreas Capan-1 0.63407 -0.65729 0.02087 0.48032 DataSet_01_170
SELL TP53 siRNA Lung SAECs 7.83333 2.96963 0.0024 0.16502 DataSet_01_175
SELL TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.45962 -1.12149 - - DataSet_01_196
SELL TP63 siRNA Immortalized_keratinocyte HaCaT 5.24603 2.39123 - - DataSet_01_200
SELL TP63 siRNA Head_and_neck SCC-6 1.53444 0.61771 - - DataSet_01_202
SELL MITF shRNA Skin COLO829 1.72415 0.78589 0.00109 0.02287 DataSet_01_207
SELL FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.50221 -0.99363 - - DataSet_01_209
SELL FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.13921 1.6504 - - DataSet_01_210
SELL SOX11 shRNA Lymph MCL 0.54768 -0.86861 0.00059 0.11823 DataSet_01_213
SELL LIN28A siRNA Embryo H9 0.48084 -1.05638 0.00296 0.02364 DataSet_01_215
SELL TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.96387 0.9737 0.00029 0.00828 DataSet_01_217
SELL IRX1 shRNA Bone_marrow 143B 0.4459 -1.1652 0.00041 0.02481 DataSet_01_227
SELL FOXP1 siRNA Prostate LNCaP 0.40007 -1.32168 0.00608 0.22088 DataSet_01_234
SELL TWIST1 shRNA Stomach CAF14 2.40213 1.26432 0.08034 0.99996 DataSet_01_252
SELL IRF4 shRNA Lymph BL2 0.5585 -0.84036 - - DataSet_01_262
SELL TLX1 shRNA Haematopoietic_and_lymphoid_tissue ALLSIL 1.62898 0.70397 0.32807 0.99999 DataSet_01_263
SELL CREB1 shRNA Haematopoietic_and_lymphoid_tissue Molt4 0.63263 -0.66057 0.251 0.99988 DataSet_01_273
SELL STAT5 shRNA Prostate CWR22Pc 2.07129 1.05053 0.00342 0.0284 DataSet_01_279
SELL AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 2.647 1.40436 3.48022e-07 4.25406e-05 DataSet_01_283
SELL POSTN shRNA Brain GSC272 3.93377 1.97591 0.01702 0.48721 DataSet_01_293
SELL TFAP4 siRNA Brain BE(2)-C 0.25218 -1.98747 0.40152 0.51625 DataSet_01_295
SELL PTEN shRNA Skin A431 0.32867 -1.60529 0.19434 0.38714 DataSet_01_301
SELL TFAP2C siRNA Lung NCI-H292 1.58486 0.66436 - - DataSet_01_312
SELL FOXO1 shRNA Haematopoietic_and_lymphoid_tissue RS4;11 0.64071 -0.64226 0.00515 0.06235 DataSet_01_321
SELL TP63 shRNA Head_and_neck FaDU 1.79104 0.8408 3.52652e-05 0.0011 DataSet_01_327
SELL TP63 shRNA Head_and_neck FaDU 1.79104 0.8408 3.52652e-05 0.0011 DataSet_01_330
SELL RBM17 shRNA Liver HepG2 1.61538 0.69188 0.32289 0.58645 DataSet_02_100
SELL RBFOX2 shRNA Liver HepG2 3.38462 1.75899 0.20162 0.66758 DataSet_02_101
SELL FIP1L1 shRNA Liver HepG2 4 2 0.01522 0.05257 DataSet_02_103
SELL HDGF shRNA Liver HepG2 2.16667 1.11548 0.82721 0.90229 DataSet_02_104
SELL U2AF2 shRNA Liver HepG2 0.57576 -0.79647 0.86644 0.91768 DataSet_02_105
SELL TAF15 shRNA Liver HepG2 10.2 3.3505 0.00539 0.02146 DataSet_02_106
SELL ZNF622 shRNA Liver HepG2 0.27273 -1.87447 0.49891 0.5727 DataSet_02_108
SELL GTF2F1 shRNA Liver HepG2 0.60606 -0.72247 0.63034 0.8431 DataSet_02_110
SELL BCLAF1 shRNA Liver HepG2 2.375 1.24793 0.05178 0.12405 DataSet_02_112
SELL PCBP1 shRNA Liver HepG2 6 2.58496 0.01985 0.04965 DataSet_02_115
SELL SUB1 shRNA Liver HepG2 0.21212 -2.23704 0.2172 0.40598 DataSet_02_117
SELL RBM25 shRNA Liver HepG2 2 1 0.602 0.6862 DataSet_02_119
SELL PTBP1 shRNA Liver HepG2 5 2.32193 0.0142 0.02923 DataSet_02_120
SELL EWSR1 shRNA Liver HepG2 2.5 1.32193 0.48062 0.59722 DataSet_02_122
SELL PCBP2 shRNA Liver HepG2 0.27273 -1.87447 0.33778 0.5101 DataSet_02_123
SELL FUS shRNA Liver HepG2 4.78788 2.25939 0.086 0.23427 DataSet_02_124
SELL HNRNPLL shRNA Liver HepG2 0.25 -2 0.45869 0.54274 DataSet_02_125
SELL SRSF3 shRNA Liver HepG2 1.66667 0.73697 0.71495 0.81478 DataSet_02_127
SELL PRPF4 shRNA Liver HepG2 0.11765 -3.08746 0.10791 0.20809 DataSet_02_128
SELL MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.125 -3 0.03238 1 DataSet_02_173
SELL KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.1107 1 DataSet_02_184
SELL CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.07829 1 DataSet_02_185
SELL RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.44444 -1.16993 0.46486 1 DataSet_02_190
SELL ATOH8 siRNA Umbilical_vein HUVEC 0.63918 -0.645707 0.492982949214509 1 DataSet_03_019
SELL CEBPA siRNA Mammary_gland MCF7 1.57578 0.656065 0.0395228169022969 0.999962793175751 DataSet_03_047
SELL CEBPB siRNA Embryo hESC 0.465504 -1.10313 0.113940648025463 0.487612520800666 DataSet_03_049
SELL CENPF siRNA Mammary_gland MCF7 1.68224 0.750386 0.0237100371996537 0.999662524742916 DataSet_03_052
SELL CTNNB1 siRNA Mammary_gland MCF7 2.47284 1.30617 0.00172877499727613 0.999436862066063 DataSet_03_058
SELL FOXM1 siRNA Oesophagus TE1 0.606036 -0.722525 0.00529981326721194 1 DataSet_03_093
SELL GATA4 siRNA Stomach KatoIII 0.636936 -0.650779 0.242380979367022 0.914908611202096 DataSet_03_106
SELL GATA6 siRNA Stomach AGS 1.53247 0.615863 0.0271497968541614 0.405468173018528 DataSet_03_108
SELL HIC1 CRISPR Prostate PC3 2.34297 1.22834 - - DataSet_03_118
SELL HOXB7 siRNA Mammary_gland MCF7 0.560814 -0.834404 0.0152590565064676 0.999977683706165 DataSet_03_127
SELL IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 3.28885 1.71758 0.00573190116927454 0.517184665919334 DataSet_03_134
SELL MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.356012 -1.49 0.00038256043644651 0.301745182733087 DataSet_03_155
SELL MEF2D shRNA Liver HuH7 1.72652 0.787868 - - DataSet_03_162
SELL MYB siRNA Cord_Blood CD34+ progenitor cells 2.2306 1.15743 - - DataSet_03_170
SELL MYC siRNA Colon HT29 1.75651 0.812711 - - DataSet_03_177
SELL NR2F2 siRNA Uterus Primary eutopic stromal cells 2.20249 1.13913 0.111502919134858 0.99947668859931 DataSet_03_202
SELL PCNA siRNA Mammary_gland MCF7 1.64631 0.719239 0.0280195782098935 0.999448838103647 DataSet_03_210
SELL PPARG siRNA Peripheral_blood GM-CSF Macrophage 0.622725 -0.683333 0.0378299007125714 0.838659367420472 DataSet_03_214
SELL SATB1 siRNA Peripheral_blood CD4+ T cells 1.6518 0.724036 0.124740245216145 0.999960966858709 DataSet_03_231
SELL SPIB siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly3 0.527295 -0.923316 9.45789395400026e-07 0.00234380123457204 DataSet_03_253
SELL STAT5B siRNA Mammary_gland MCF7 1.525 0.608806 0.0513174871017247 0.999932708473107 DataSet_03_263
SELL STAT6 siRNA Umbilical_vein HUVEC 0.481122 -1.05553 0.0397599413132212 0.697732195411512 DataSet_03_264
SELL TET1 siRNA Embryo NCCIT 0.612357 -0.707555 0.000791646604642857 0.00937069955023417 DataSet_03_269
SELL TFAP2C siRNA Mammary_gland MCF7 1.57073 0.65144 0.1831526871726 0.535390313272495 DataSet_03_274
SELL TFE3 siRNA Kidney UOK257-2 0.275997 -1.85728 - - DataSet_03_275
SELL TP53 siRNA Mammary_gland MCF7 1.58207 0.661813 0.0382949493790282 0.999938217444253 DataSet_03_277
SELL CTCF CRISPR Liver HepG2 1.71429 0.777608 0.705725875831537 0.958268523428557 DataSet_04_027
SELL ERN1 CRISPR Liver HepG2 0.368421 -1.44057 0.285114684402508 0.492341935235757 DataSet_04_029
SELL FUBP1 shRNA Liver HepG2 0.631579 -0.662965 0.633601572808781 0.844478022015323 DataSet_04_030
SELL NFX1 CRISPR Liver HepG2 2.42308 1.27684 0.205005074637683 0.292158304775623 DataSet_04_032
SELL PAN2 CRISPR Liver HepG2 7 2.80735 0.000310751059945528 0.0821848765220944 DataSet_04_033
SELL SMAD5 CRISPR Liver HepG2 10.5 3.39232 0.0046148511143395 0.367798690114644 DataSet_04_036
SELL SRPK2 CRISPR Liver HepG2 0.631579 -0.662965 0.658217677784497 0.795567194923698 DataSet_04_037
SELL WRN shRNA Liver HepG2 0.210526 -2.24793 0.114086643972562 0.331186538700979 DataSet_04_038
SELL ZNF574 CRISPR Liver HepG2 13 3.70044 0.00682227331630121 0.0644917278546999 DataSet_04_041
SELL DDX20 CRISPR Liver HepG2 0.526316 -0.925999 0.424474419358037 0.568028804178094 DataSet_04_043
SELL APTX CRISPR Liver HepG2 1.71429 0.777608 0.501484822593056 0.932481731675335 DataSet_04_069
SELL DNMT3B CRISPR Liver HepG2 1.90909 0.932886 0.297292601267772 0.566585643242372 DataSet_04_044
SELL RIOK2 CRISPR Liver HepG2 71 6.14975 0.191627238908088 0.956011506471202 DataSet_04_070
SELL SEPT11 CRISPR Liver HepG2 0.272727 -1.87447 0.146633878127702 0.382231191619694 DataSet_04_068
SELL ABT1 shRNA Liver HepG2 1.84615 0.884523 0.386194620381603 0.517598960507564 DataSet_04_052
SELL CALR shRNA Liver HepG2 0.125 -3 0.220954404053778 0.347466015053878 DataSet_04_053
SELL CCAR1 shRNA Liver HepG2 10.3333 3.36923 0.00706875899470753 0.0398801635808605 DataSet_04_054
SELL CNOT7 shRNA Liver HepG2 3.38462 1.75899 0.13854154330505 0.216610208583516 DataSet_04_051
SELL PRPF6 shRNA Liver HepG2 2.12121 1.08489 0.213866052453347 0.419273112196101 DataSet_04_056
SELL UBE2L3 shRNA Liver HepG2 0.363636 -1.45943 0.306430332025359 0.457482957755784 DataSet_04_055
SELL YBX3 shRNA Liver HepG2 0.307692 -1.70044 0.0363045295954845 0.140640546411039 DataSet_02_98
SELL CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.452381 -1.14439 0.250002868410431 0.515493765941315 DataSet_02_38
SELL HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.4 2.1375 0.171955415446861 0.568318251270103 DataSet_02_75
SELL LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.428571 -1.22239 0.214661761392363 0.370490299292004 DataSet_02_35
SELL TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.134689187688812 0.280451477504507 DataSet_02_43
SELL TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.428571 -1.22239 0.187474165539924 0.317485763281952 DataSet_02_33
SELL SMARCA4 siRNA Colon HCT116 0.592472 -0.755182 6.650669e-02 8.476247e-01 DataSet_03_301
SELL SMARCA4 siRNA Colon HCT116 0.614652 -0.702159 6.786408e-02 0.2619150 DataSet_03_302
SELL SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.630617 -0.665163 3.436536e-01 0.6709252 DataSet_03_306
SELL BRCA1 siRNA Mammary_gland MCF7 0.617115 -0.696389 2.140161e-03 0.6269749 DataSet_03_308
SELL EZH2 shRNA Mammary_gland MCF7 0.435207 -1.20022 1.652180e-06 2.537068e-04 DataSet_03_331
SELL EZH2 knockdown Colon HCT116 0.592485 -0.75515 0.058913336 0.8488990 DataSet_03_334
SELL EZH2 shRNA Mammary_gland LM2 3.59711 1.84684 2.485910e-02 2.407797e-01 DataSet_03_350
SELL SKI CRISPR Blood HL60 3.63443 1.86173 2.535977e-03 0.102039778 DataSet_03_351
SELL ETV5 knockdown Colon HT29 0.369231 -1.43741 6.424060e-03 0.094221670 DataSet_03_353
SELL PARP1 siRNA Prostate LNCaP 2.33772 1.2251 5.070408e-03 0.099543671 DataSet_03_354
SELL CREBBP CRISPR Brain U5-NPC 1.94086 0.956696 0.7783396000 0.8674856 DataSet_03_356
SELL PTPN14 CRISPR Brain U5-NPC 0.292517 -1.77341 9.734387e-02 0.32322579 DataSet_03_357
SELL RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 1.5947 0.673284 1.453066e-01 3.682494e-01 DataSet_03_359
SELL ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 1.52647 0.610196 1.046326e-04 5.973632e-04 DataSet_03_362
SELL TPR shRNA Bone_marrow U2OS 0.605409 -0.724018 2.013737e-02 2.088244e-01 DataSet_03_370
SELL E2F1 siRNA Nasopharynx HK1 0.347826 -1.52356 2.958920e-01 9.722824e-01 DataSet_03_373
SELL EZH2 CRISPR Ovary SKOV3 34 5.08746 6.322538e-04 0.0162244471 DataSet_03_378
SELL DDX5 shRNA Stomach HGC-27 1.53226 0.615659 - - DataSet_03_379
SELL TCF19 CRISPR Oral_squamous CAL27 0.392927 -1.34767 2.831684e-03 0.0346654755 DataSet_03_383
SELL TRIM8 siRNA Mammary_gland MCF7 0.439474 -1.18615 1.515626e-02 0.0690145627 DataSet_03_388
SELL NFKBIA shRNA Bone_marrow U2OS 0.303169 -1.72181 9.857917e-01 0.99508270 DataSet_03_389
SELL ILF2 siRNA Stomach SGC-7901 0.25 -2 0.3132694608 0.50566494 DataSet_03_393
SELL RELA CRISPR Brain T30 0.648899 -0.623934 0.4226702088 0.8400824 DataSet_03_399
SELL EHF shRNA Stomach MKN7 2.07687 1.05441 - - DataSet_03_402
SELL TFAP2A knockout Embryo H9 2.1 1.07039 5.620934e-03 0.05151366 DataSet_03_405
SELL SATB2 CRISPR Colon Colon organoid 3.33333 1.73697 7.716987e-02 0.95735254 DataSet_03_406
SELL STRAP knockout Nerve SK-N-AS 1.67439 0.743636 - - DataSet_03_409
SELL USP22 shRNA Liver HuH7 4.50033 2.17003 - - DataSet_03_411
SELL E2F6 shRNA Liver HuH7 0.194005 -2.36584 - - DataSet_03_412
SELL RUNX2 shRNA Cord_blood Natural Killer Cell 2.18416 1.12708 2.769461e-02 0.793390621 DataSet_03_416
SELL BRD4 CRISPR Lymph CD8+ T cells 0.572822 -0.803842 - - DataSet_03_420
SELL FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.503588 -0.989685 - - DataSet_03_422
SELL STAT5B CRISPR Embryo_kidney HEK293 1.6 0.678072 3.599290e-01 0.713024399 DataSet_03_424
SELL USP7 shRNA Skin xenograft cells 0.536211 -0.899127 0.34247852 0.4803886 DataSet_03_431
SELL PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.394192 -1.34303 - - DataSet_03_432
SELL POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.511574 -0.966985 1.124561e-01 0.500930674 DataSet_03_434
SELL SUFU shRNA Mammary_gland HCC1954 cells 0.543478 -0.879706 0.1708851287 0.6455297 DataSet_03_437
SELL FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.82353 0.866733 6.509997e-01 0.98357482 DataSet_03_439
SELL SETDB1 shRNA Colon HCT116 0.554402 -0.850997 - - DataSet_03_440
SELL DAXX shRNA Mammary_gland MDA-MB-231 0.606576 -0.72124 7.049093e-01 0.88491333 DataSet_03_441
SELL CAMTA1 knockout Embryo_kidney HEK293T 2.16667 1.11548 9.985498e-02 0.25961613 DataSet_03_448
SELL CBX2 siRNA Mammary_gland MDA-MB-231 0.182267 -2.45588 1.405929e-02 5.991943e-02 DataSet_03_450
SELL CBX2 siRNA Mammary_gland MCF7 1.98769 0.991096 2.503721e-01 0.3979896139 DataSet_03_451
SELL OGT siRNA Embryo BeWo cells 0.5 -1 4.494673e-01 0.76317389 DataSet_03_453
SELL SREBF2 siRNA Umbilical_vein HUVEC 5.31393 2.40978 2.176096e-02 2.344148e-01 DataSet_03_457
SELL IRF2 shRNA Cord_Blood CD34+ cells 0.659804 -0.59989 - - DataSet_03_460
SELL TXNIP shRNA Cord_Blood CD34+ cells 1.54312 0.62585 - - DataSet_03_461
SELL TXNIP shRNA Cord_blood ST3 1.64397 0.717184 1.219315e-01 0.4037279154 DataSet_03_462
SELL SMARCA1 Cas13 Embryo_kidney HEK293T 0.25 -2 - - DataSet_03_466
SELL SMARCA1 shRNA Embryo_kidney HEK293T 0.25 -2 - - DataSet_03_468
SELL LIN28A siRNA Mammary_gland MCF7M 4.79114 2.26037 6.833200e-02 0.3646840 DataSet_03_469
SELL LIN28A siRNA Mammary_gland MCF7M 4.79114 2.26037 6.833200e-02 0.3646840 DataSet_03_470
SELL WHSC1 siRNA Prostate PC3 0.383686 -1.382 1.535077e-02 0.12540055 DataSet_03_471
SELL EZH2 siRNA Umbilical_vein HUVEC 0.619048 -0.691878 4.880205e-02 0.259512324 DataSet_03_473
Regulation Region
 
T(co)Fs that significantly regulate SMAD5 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of SELL
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines