Gene Overview
Target Gene: SOX8
NCBI Official Symbol: SOX8
Entrez ID: 30812
Ensembl ID: ENSG00000005513
Gene Full Name: SRY-box 8
Strand: +
Gene Locus: 16p13.3
External Links:

SOX8 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate SOX8   
T(co)Fs that Repress SOX8
The Intensity of the Gene Regulated by T(co)Fs:
SOX8-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
SOX8 FOXO1 shRNA Bone EWS-FLI1 1.61094 0.6879 0.00107 0.05724 DataSet_01_106
SOX8 HOXA1 siRNA Lung_fibroblast IMR-90 4.08882 2.03168 0.00012 0.01265 DataSet_01_110
SOX8 ID1 siRNA Lung A549 0.44971 -1.15293 0.01343 0.15392 DataSet_01_117
SOX8 ID1 siRNA Lung H1650 0.55652 -0.8455 0.32804 0.65994 DataSet_01_118
SOX8 BRD4 shRNA Embryo_kidney HEK293 1.75747 0.8135 - - DataSet_01_119
SOX8 ZIC2 siRNA Pancreas PANC1 3.15825 1.65912 - - DataSet_01_121
SOX8 FOXM1 siRNA Central_nervous_system U87 0.05138 -4.28275 - - DataSet_01_122
SOX8 ID1 shRNA Neuroepithelium GSC2 0.51495 -0.95749 1.36628e-11 3.84312e-10 DataSet_01_133
SOX8 POLR3A siRNA Mammary_gland MCF7 2.70588 1.4361 - - DataSet_01_139
SOX8 LIN28B siRNA Embryo_kidney HEK293 0.62547 -0.677 0.02127 0.08866 DataSet_01_153
SOX8 HSF1 shRNA Skin A375 0.33333 -1.58496 0.16179 0.4009 DataSet_01_155
SOX8 ETV1 shRNA Prostate LNCaP 0.44006 -1.18422 2.2127e-06 4.65756e-05 DataSet_01_161
SOX8 ELK1 siRNA Peripheral_blood CD4+ T cells 1758.9 10.7805 0.01325 0.06231 DataSet_01_162
SOX8 JUN siRNA Peripheral_blood CD4+ T cells 5.01514 2.32629 1.50617e-05 0.00139 DataSet_01_164
SOX8 MAF siRNA Peripheral_blood CD4+ T cells 4.89792 2.29217 1.56148e-05 0.00206 DataSet_01_165
SOX8 NFATC3 siRNA Peripheral_blood CD4+ T cells 3.69502 1.88558 0.00031 0.01306 DataSet_01_166
SOX8 NR4A1 siRNA Pancreas PANC1 1.59844 0.67667 5.35471e-05 0.00248 DataSet_01_174
SOX8 GATA2 siRNA Prostate LNCaP 0.37712 -1.4069 0.00018 0.00161 DataSet_01_193
SOX8 CREB1 shRNA Parotid_gland H3118 MEC 2.06093 1.04329 0.02594 0.25485 DataSet_01_194
SOX8 CREB1 shRNA Parotid_gland HSY 1.50146 0.58637 0.64159 0.98114 DataSet_01_195
SOX8 TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.0367 1.02623 - - DataSet_01_197
SOX8 TP63 siRNA Head_and_neck SCC-1 2.7305 1.44916 - - DataSet_01_199
SOX8 XBP1 shRNA Mammary_gland MDA-MB-231 1.57007 0.65083 0.01188 0.07489 DataSet_01_204
SOX8 HIC1 shRNA Mammary_gland HBL100 2.36392 1.24118 - - DataSet_01_205
SOX8 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.35738 -1.48447 - - DataSet_01_209
SOX8 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 3.13528 1.64859 0.30786 0.49819 DataSet_01_217
SOX8 HIF1A shRNA Liver HuH7 2.05975 1.04247 - - DataSet_01_224
SOX8 SNAI2 shRNA Skin Primary human keratinocytes 18.656 4.22156 0.12196 0.23819 DataSet_01_225
SOX8 MYC shRNA Soft_tissue HT1080 0.56943 -0.81241 - - DataSet_01_237
SOX8 SOX4 shRNA Mammary_gland MDA-MB-231 0.6074 -0.71929 0.08132 0.33908 DataSet_01_260
SOX8 MYT1L shRNA Fetal_spinal_cord SPC04 0.48262 -1.05104 0.00035 0.05793 DataSet_01_264
SOX8 POSTN shRNA Brain GSC272 3.25901 1.70443 0.15301 0.57242 DataSet_01_293
SOX8 TFAP4 siRNA Brain BE(2)-C 0.19329 -2.37118 0.34006 0.51625 DataSet_01_295
SOX8 PTEN shRNA Lung HCC827 1.8419 0.8812 0.2767 0.71076 DataSet_01_302
SOX8 PTEN shRNA Mammary_gland SKBR3 1.59472 0.6733 0.03227 0.53657 DataSet_01_303
SOX8 SOX9 siRNA Prostate VCaP 3.375 1.75489 0.51602 0.94497 DataSet_01_308
SOX8 SOX9 siRNA Prostate VCaP 3.375 1.75489 0.51602 0.94497 DataSet_01_309
SOX8 ELK3 shRNA Mammary_gland MDA-MB-231 3.86126 1.94907 0.00034 0.00146 DataSet_01_318
SOX8 MYC siRNA Colon HCT116 0.38675 -1.37051 1.13334e-08 2.21996e-07 DataSet_01_324
SOX8 GATA3 siRNA Oral_cavity OEC-M1 0.57749 -0.79212 0.49339 0.99787 DataSet_01_347
SOX8 HIF1A siRNA Oral_cavity OEC-M1 2.49725 1.32034 0.20043 0.85151 DataSet_01_348
SOX8 SOX2 shRNA Neuroepithelium HF2303 0.36713 -1.44566 0.00756 1 DataSet_01_349
SOX8 CDX2 siRNA Colon COLO320 0.53532 -0.90154 - - DataSet_01_357
SOX8 GTF2B siRNA Cervix HeLa 0.55059 -0.86096 - - DataSet_01_362
SOX8 RBFOX2 shRNA Liver HepG2 3.15789 1.65896 0.08156 0.65168 DataSet_02_101
SOX8 SAFB2 shRNA Liver HepG2 0.42 -1.25154 0.03694 0.08664 DataSet_02_102
SOX8 HDGF shRNA Liver HepG2 1.62264 0.69834 0.0051 0.07713 DataSet_02_104
SOX8 SSB shRNA Liver HepG2 0.08108 -3.62449 8e-04 0.00687 DataSet_02_107
SOX8 ZNF622 shRNA Liver HepG2 0.04651 -4.42626 0.00019 0.00543 DataSet_02_108
SOX8 HNRNPUL1 shRNA Liver HepG2 0.44 -1.18442 0.01423 0.04881 DataSet_02_109
SOX8 RBM39 shRNA Liver HepG2 0.52632 -0.926 0.59455 0.77974 DataSet_02_111
SOX8 PCBP1 shRNA Liver HepG2 1.85 0.88753 0.01975 0.04948 DataSet_02_115
SOX8 TARDBP shRNA Liver HepG2 0.30435 -1.71621 0.02053 0.05679 DataSet_02_116
SOX8 SUB1 shRNA Liver HepG2 1.875 0.90689 0.15573 0.3386 DataSet_02_117
SOX8 CEBPZ shRNA Liver HepG2 0.52381 -0.93289 0.24689 1 DataSet_02_118
SOX8 PTBP1 shRNA Liver HepG2 2.25 1.16993 0.13783 0.18022 DataSet_02_120
SOX8 EWSR1 shRNA Liver HepG2 0.37736 -1.40599 0.00774 0.05635 DataSet_02_122
SOX8 FUS shRNA Liver HepG2 0.1875 -2.41504 0.04787 0.17107 DataSet_02_124
SOX8 HNRNPLL shRNA Liver HepG2 0.17391 -2.52356 0.02693 0.06227 DataSet_02_125
SOX8 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.05734 0.32221 DataSet_02_129
SOX8 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.06086 0.12862 DataSet_02_131
SOX8 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.08227 0.30939 DataSet_02_133
SOX8 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.84667 0.90652 DataSet_02_134
SOX8 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.04523 0.15565 DataSet_02_135
SOX8 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.47968 0.66759 DataSet_02_141
SOX8 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 1 1 DataSet_02_143
SOX8 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.21429 -2.22239 0.16949 0.53735 DataSet_02_145
SOX8 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.03442 0.13097 DataSet_02_147
SOX8 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.17149 0.45844 DataSet_02_148
SOX8 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.0824 0.26793 DataSet_02_149
SOX8 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.36364 -1.45943 0.16716 0.60973 DataSet_02_150
SOX8 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.35714 -1.48543 0.3761 0.56142 DataSet_02_151
SOX8 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.27588 0.58141 DataSet_02_152
SOX8 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.625 -0.67807 0.09748 0.31702 DataSet_02_155
SOX8 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.14286 -2.80735 0.4083 0.69353 DataSet_02_156
SOX8 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.15372 0.76193 DataSet_02_161
SOX8 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.01423 0.53443 DataSet_02_162
SOX8 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.84128 0.92545 DataSet_02_167
SOX8 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.08641 0.18746 DataSet_02_168
SOX8 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 1 1 DataSet_02_169
SOX8 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.31128 1 DataSet_02_174
SOX8 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.5413 1 DataSet_02_175
SOX8 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 13 3.70044 0.41988 1 DataSet_02_176
SOX8 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.29713 1 DataSet_02_180
SOX8 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.43458 1 DataSet_02_183
SOX8 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 1 1 DataSet_02_185
SOX8 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.0322 1 DataSet_02_188
SOX8 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 10 3.32193 0.44 1 DataSet_02_189
SOX8 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.84707 1 DataSet_02_190
SOX8 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.07474 1 DataSet_02_191
SOX8 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.06313 1 DataSet_02_192
SOX8 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 6.25 2.64386 0.42906 1 DataSet_02_194
SOX8 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 11 3.45943 0.02872 1 DataSet_02_195
SOX8 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 4.5 2.16993 0.00151 0.12618 DataSet_02_196
SOX8 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.12403 1 DataSet_02_198
SOX8 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 1.55556 0.63743 0.87074 1 DataSet_02_199
SOX8 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.06671 1 DataSet_02_202
SOX8 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.0665 1 DataSet_02_205
SOX8 AR siRNA Prostate LNCaP 3.03256 1.60054 0.282319545851072 1 DataSet_03_005
SOX8 ASCL1 siRNA Lung DMS79 0.641857 -0.639675 0.153491232379018 0.812368038692406 DataSet_03_016
SOX8 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.276925 -1.85243 0.0619784539729259 0.73080575438439 DataSet_03_025
SOX8 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.19847 1.1365 - - DataSet_03_096
SOX8 GATA2 siRNA Uterus Decidual stromal cells 0.480282 -1.05805 0.564121685949578 0.948406368654038 DataSet_03_100
SOX8 GATA4 siRNA Stomach YCC3 2.30959 1.20764 0.100790942531273 0.646128706007691 DataSet_03_107
SOX8 GATA6 siRNA Stomach YCC3 1.75728 0.813348 0.435935437293617 0.887401945346237 DataSet_03_110
SOX8 HNF4a siRNA Liver HepG2 4.66667 2.22239 0.0890461981441205 0.703859565587688 DataSet_03_126
SOX8 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.02238 1.01606 0.538303393545218 0.999948959532916 DataSet_03_134
SOX8 MITF siRNA Skin MZ7 4.58279 2.19622 1.65090788544104e-11 1.06067774402762e-09 DataSet_03_165
SOX8 MITF siRNA Skin Ma-Mel-15 4.25582 2.08944 3.97645568606392e-05 0.00679119575209019 DataSet_03_166
SOX8 MITF siRNA Skin Ma-Mel-15 3.96122 1.98595 1.37529797366609e-07 5.18517233854151e-05 DataSet_03_167
SOX8 MITF siRNA Skin SK-MEL-5 0.636491 -0.651788 0.00470537738034848 0.0115804395980334 DataSet_03_168
SOX8 MYC siRNA Colon HT29 0.116653 -3.0997 - - DataSet_03_177
SOX8 MYC siRNA Central_nervous_system DAOY M2.1 0.249979 -2.00012 5.9193813441608e-07 5.48264341350736e-06 DataSet_03_178
SOX8 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.221938 -2.17177 5.83958347537092e-05 0.000926418902264889 DataSet_03_211
SOX8 SOX2 CRISPR Seminoma-like TCam-2 0.488722 -1.03291 0.0242861090178754 0.999580851453413 DataSet_03_244
SOX8 SP1 siRNA Ovary OVSAYO 0.646948 -0.628278 0.163286415633279 0.473120998476709 DataSet_03_251
SOX8 SRF siRNA Prostate LNCaP 2.58887 1.37232 0.0215897703537387 0.107304676844207 DataSet_03_254
SOX8 STAT6 siRNA Umbilical_vein HUVEC 4.86486 2.2824 0.179856260925778 0.837635960915423 DataSet_03_264
SOX8 TFAP2C siRNA Mammary_gland MCF7 4.80296 2.26393 0.00790737870488357 0.254524554051381 DataSet_03_274
SOX8 TFE3 siRNA Kidney UOK257-2 1.66134 0.732351 - - DataSet_03_275
SOX8 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.0797821686010524 0.598730530090409 DataSet_04_001
SOX8 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.163376511823762 0.28358470698003 DataSet_04_002
SOX8 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 122.017 6.93093 3.74725175523079e-05 0.00235439834804835 DataSet_04_014
SOX8 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.28571 1.19264 0.148200900827007 0.297108062672558 DataSet_04_023
SOX8 E4F1 CRISPR Liver HepG2 2.625 1.39232 0.179770498094581 0.46711169559422 DataSet_04_028
SOX8 ERN1 CRISPR Liver HepG2 0.571429 -0.807355 0.0114782183284953 0.101061756604025 DataSet_04_029
SOX8 NFX1 CRISPR Liver HepG2 0.352941 -1.5025 0.00118532699883144 0.0142780842269676 DataSet_04_032
SOX8 SRPK2 CRISPR Liver HepG2 0.589286 -0.762961 0.0106959346827025 0.130851055354647 DataSet_04_037
SOX8 WRN shRNA Liver HepG2 0.553571 -0.853159 0.0553464337089167 0.250244312573332 DataSet_04_038
SOX8 ZC3H8 shRNA Liver HepG2 0.411765 -1.28011 0.0993709619627114 0.262031687832108 DataSet_04_040
SOX8 ZNF574 CRISPR Liver HepG2 0.652174 -0.616671 0.00737871020724226 0.0665483768051875 DataSet_04_041
SOX8 ACTN4 CRISPR Liver HepG2 0.097561 -3.35755 6.1345937128262e-05 0.0290651341479898 DataSet_04_042
SOX8 DDX20 CRISPR Liver HepG2 0.5 -1 0.0166375587319713 0.0840277245095518 DataSet_04_043
SOX8 RIOK2 CRISPR Liver HepG2 3 1.58496 0.782409748011303 1 DataSet_04_070
SOX8 SEPT11 CRISPR Liver HepG2 0.294118 -1.76553 0.0412488821014894 0.1966859755026 DataSet_04_068
SOX8 CALR shRNA Liver HepG2 0.25 -2 0.04646082064644 0.107137151203825 DataSet_04_053
SOX8 CNOT7 shRNA Liver HepG2 1.625 0.70044 0.306142010128075 0.41162870178785 DataSet_04_051
SOX8 NPM1 shRNA Liver HepG2 0.315789 -1.66297 0.528881617239084 0.86900797244714 DataSet_04_058
SOX8 PRPF6 shRNA Liver HepG2 0.5 -1 0.276313074414397 0.490942495477305 DataSet_04_056
SOX8 YBX3 shRNA Liver HepG2 0.46 -1.12029 0.118016873505502 0.273850760304187 DataSet_02_98
SOX8 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.809075845185239 0.912951309899281 DataSet_04_048
SOX8 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.803986488536923 0.957348252118587 DataSet_04_050
SOX8 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.433333 -1.20645 0.203918229252887 0.465012743100738 DataSet_02_38
SOX8 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.158977602506661 0.286718654365684 DataSet_02_14
SOX8 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.166185446013821 0.306096513211228 DataSet_02_35
SOX8 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.433333 -1.20645 0.26939765505832 0.424221990970998 DataSet_02_47
SOX8 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.566667 -0.819428 0.382768498257466 0.573105501152937 DataSet_02_43
SOX8 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.433333 -1.20645 0.201622547392584 0.335772728834854 DataSet_02_33
SOX8 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.209002141158264 0.367132055179007 DataSet_02_53
SOX8 CNOT3 shRNA Lung A549 1.76231 0.817467 1.864124e-01 0.8846481 DataSet_03_340
SOX8 EZH2 shRNA Colon SW480 1.53017 0.61369 - - DataSet_03_298
SOX8 NFKBIZ knockout Colon Colon organoid 1.74125 0.800125 2.892241e-01 0.716774052 DataSet_03_323
SOX8 EZH2 knockdown Uterus Ishikawa (ISK) cell 0.382447 -1.38667 - - DataSet_03_324
SOX8 SMARCA4 siRNA Colon HCT116 1.68087 0.749212 8.933051e-03 0.1352359 DataSet_03_302
SOX8 ELF3 CRISPR Bile_duct HBDEC2 0.648388 -0.62507 6.130767e-04 4.268699e-03 DataSet_03_304
SOX8 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.658455 -0.602844 3.301418e-02 0.6330193 DataSet_03_306
SOX8 SNAI2 shRNA Pancreas KLM1 0.372375 -1.42517 1.238744e-03 0.10654357 DataSet_03_307
SOX8 PRMT1 shRNA Lung A549 1.58895 0.668078 - - DataSet_03_342
SOX8 ACTR5 siRNA Muscle RD 1.67353 0.742895 - - DataSet_03_343
SOX8 ARID3B CRISPR Colon HCT15 0.503541 -0.98982 - - DataSet_03_335
SOX8 ESR1 siRNA Mammary_gland MCF7 1.91825 0.939793 4.700557e-03 0.0435907388 DataSet_03_352
SOX8 ETV5 knockdown Colon HT29 5.45455 2.44746 2.130179e-05 0.011889712 DataSet_03_353
SOX8 PTPN14 CRISPR Brain U5-NPC 0.191248 -2.38649 5.089232e-04 0.10763469 DataSet_03_357
SOX8 NCOA2 siRNA Uterus endometrial stromal cells 0.65 -0.621488 0.1706228779 1 DataSet_03_360
SOX8 ZNF213 siRNA Mammary_gland MCF7 0.307493 -1.70137 6.134182e-01 8.058301e-01 DataSet_03_376
SOX8 EZH2 CRISPR Ovary SKOV3 13 3.70044 2.794203e-02 0.1371234990 DataSet_03_378
SOX8 DNMT1 siRNA Skin Human melanoma cells 0.65568 -0.608937 4.872909e-05 3.147735e-04 DataSet_03_382
SOX8 TRIM8 siRNA Mammary_gland MCF7 4 2 4.475982e-01 0.6419155967 DataSet_03_388
SOX8 NFKBIA shRNA Bone_marrow U2OS 0.321223 -1.63835 4.527021e-01 0.87005461 DataSet_03_389
SOX8 YY1 knockdown Liver HepG2 4.44231 2.15131 4.245823e-05 3.467556e-04 DataSet_03_390
SOX8 ASXL1 CRISPR Embryo iPSC 2.12554 1.08783 0.0483492700 0.8048302 DataSet_03_394
SOX8 IKZF2 CRISPR Lymph CAR T Cell 0.630925 -0.664459 8.128211e-01 0.969871630 DataSet_03_397
SOX8 RELA CRISPR Brain T30 0.000380609 -11.3594 0.3249694218 0.8400824 DataSet_03_399
SOX8 SUMO1 CRISPR Bone_marrow U2OS 1.53846 0.621488 2.807571e-02 1.031181e-01 DataSet_03_401
SOX8 EHF shRNA Stomach MKN7 0.0220923 -5.50031 - - DataSet_03_402
SOX8 CDK7 shRNA Bone_marrow D458 82.5 6.36632 5.591512e-04 0.06702090 DataSet_03_404
SOX8 SIRT1 siRNA Pancreas PANC1 0.639785 -0.644341 1.449989e-02 0.062297175 DataSet_03_410
SOX8 E2F6 shRNA Liver HuH7 1.68131 0.749583 - - DataSet_03_412
SOX8 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 3.25 1.70044 6.434073e-03 0.041204933 DataSet_03_418
SOX8 FOXK2 shRNA Ovary OVCAR-5 1.62602 0.701342 3.811867e-02 0.15523001 DataSet_03_419
SOX8 FOXQ1 CRISPR Lymph Primary CD4+ T cells 4.67391 2.22463 - - DataSet_03_422
SOX8 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.259052 -1.94868 2.297483e-03 2.896861e-01 DataSet_03_428
SOX8 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 1.54545 0.628031 0.6587588292 1 DataSet_03_430
SOX8 USP7 shRNA Skin xenograft cells 0.337243 -1.56814 0.27323223 0.4348960 DataSet_03_431
SOX8 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.538462 -0.893085 - - DataSet_03_432
SOX8 NFE2L1 knockout Lung A549 1.98783 0.991193 4.240377e-01 9.984904e-01 DataSet_03_433
SOX8 EP300 knockout Pancreas HPAF-II orthotopic cells 0.142788 -2.80805 5.056906e-05 1.057318e-03 DataSet_03_436
SOX8 CAMTA1 knockout Embryo_kidney HEK293T 1.8526 0.889552 8.254131e-03 0.10886477 DataSet_03_448
SOX8 CBX2 siRNA Mammary_gland MCF7 0.380593 -1.39368 2.495610e-03 0.0106913507 DataSet_03_451
SOX8 TXNIP shRNA Cord_Blood CD34+ cells 12 3.58496 - - DataSet_03_461
SOX8 SOX9 knockout Liver HuH7 0.222222 -2.16992 2.376224e-01 4.241924e-01 DataSet_03_463
SOX8 SMARCA1 Cas13 Embryo_kidney HEK293T 0.550409 -0.861425 - - DataSet_03_466
SOX8 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.71662 0.779572 - - DataSet_03_467
SOX8 LIN28A siRNA Mammary_gland MCF7M 2.3496 1.23242 7.980845e-01 0.9703578 DataSet_03_469
SOX8 LIN28A siRNA Mammary_gland MCF7M 2.3496 1.23242 7.980845e-01 0.9703578 DataSet_03_470
SOX8 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.4019693 0.8025579 DataSet_04_072
SOX8 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.7422629 0.853217135 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate CDK7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of SOX8
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines