Gene Overview
Target Gene: AHSG
NCBI Official Symbol: AHSG
Entrez ID: 197
Ensembl ID: ENSG00000145192
Gene Full Name: alpha 2-HS glycoprotein
Strand: +
Gene Locus: 3q27.3
External Links:

AHSG Significantly Regulated by These T(co)Fs

T(co)Fs that Activate AHSG   
T(co)Fs that Repress AHSG
The Intensity of the Gene Regulated by T(co)Fs:
AHSG-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
AHSG ID1 siRNA Lung A549 1.50447 0.58926 0.34618 0.57135 DataSet_01_117
AHSG ID1 siRNA Lung H1650 1.95977 0.97069 0.20194 0.55232 DataSet_01_118
AHSG ZIC2 siRNA Pancreas PANC1 1.67592 0.74495 - - DataSet_01_121
AHSG FOXM1 siRNA Central_nervous_system U87 0.2306 -2.11656 - - DataSet_01_122
AHSG POLR3A siRNA Mammary_gland MCF7 0.60897 -0.71555 - - DataSet_01_139
AHSG ELK1 siRNA Peripheral_blood CD4+ T cells 2.22943 1.15668 0.00283 0.02221 DataSet_01_162
AHSG GATA3 siRNA Peripheral_blood CD4+ T cells 2.76067 1.46502 0.00031 0.03495 DataSet_01_163
AHSG NFATC3 siRNA Peripheral_blood CD4+ T cells 1.57438 0.65478 0.04578 0.22351 DataSet_01_166
AHSG NFKB1 siRNA Peripheral_blood CD4+ T cells 2.92875 1.55028 0.00055 0.06004 DataSet_01_167
AHSG HSF1 shRNA Liver KYN2 0.19552 -2.35465 - - DataSet_01_178
AHSG GATA2 siRNA Prostate LNCaP 0.38421 -1.38005 0.00079 0.00489 DataSet_01_193
AHSG CREB1 shRNA Parotid_gland H3118 MEC 1.81207 0.85764 0.47741 0.77916 DataSet_01_194
AHSG TP63 siRNA Head_and_neck SCC-1 0.45455 -1.1375 - - DataSet_01_198
AHSG TP63 siRNA Immortalized_keratinocyte HaCaT 1.60843 0.68566 - - DataSet_01_200
AHSG TP63 siRNA Head_and_neck SCC-012 1.66765 0.73781 - - DataSet_01_201
AHSG TP63 siRNA Head_and_neck SCC-6 0.56204 -0.83125 - - DataSet_01_202
AHSG HIC1 shRNA Mammary_gland HBL100 0.63666 -0.65141 - - DataSet_01_205
AHSG FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 4.13231 2.04695 - - DataSet_01_209
AHSG SF1 siRNA Endometrial_tissue OsisHESC 1.73722 0.79678 0.17983 0.3313 DataSet_01_271
AHSG STAT5 shRNA Prostate CWR22Pc 1.7021 0.76731 0.04798 0.14583 DataSet_01_279
AHSG SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.51888 0.60301 0.22471 0.90406 DataSet_01_290
AHSG TFAP4 siRNA Brain BE(2)-C 0.20965 -2.25396 0.37456 0.51625 DataSet_01_295
AHSG PTEN shRNA Skin A431 1.54349 0.62619 0.22472 0.4222 DataSet_01_301
AHSG PTEN shRNA Lung HCC827 0.50941 -0.97311 0.17487 0.65768 DataSet_01_302
AHSG GTF2B siRNA Cervix HeLa 0.33531 -1.57642 - - DataSet_01_362
AHSG FIP1L1 shRNA Liver HepG2 0.25361 -1.97934 0.00101 0.01448 DataSet_02_103
AHSG U2AF2 shRNA Liver HepG2 0.41031 -1.28523 0.00705 0.0628 DataSet_02_105
AHSG TAF15 shRNA Liver HepG2 0.42724 -1.22687 0.00037 0.01075 DataSet_02_106
AHSG BCLAF1 shRNA Liver HepG2 2.64107 1.40112 0.00038 0.02408 DataSet_02_112
AHSG U2AF2 shRNA Liver HepG2 0.24942 -2.00338 0.00258 0.05392 DataSet_02_113
AHSG PCBP1 shRNA Liver HepG2 0.50478 -0.98627 0.00028 0.01339 DataSet_02_115
AHSG TARDBP shRNA Liver HepG2 3.35999 1.74846 0.00707 0.03097 DataSet_02_116
AHSG PTBP1 shRNA Liver HepG2 0.41568 -1.26644 0.00046 0.00603 DataSet_02_120
AHSG PCBP2 shRNA Liver HepG2 1.73282 0.79312 0.00364 0.05808 DataSet_02_123
AHSG FUS shRNA Liver HepG2 0.48754 -1.03642 0.00129 0.05046 DataSet_02_124
AHSG HNRNPLL shRNA Liver HepG2 5.43166 2.44139 0.00211 0.01603 DataSet_02_125
AHSG SNRNP70 shRNA Liver HepG2 1.5801 0.66001 0.20027 0.31075 DataSet_02_126
AHSG RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.59367 0.792 DataSet_02_138
AHSG MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.18151 1 DataSet_02_173
AHSG CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.12171 1 DataSet_02_187
AHSG RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.10273 1 DataSet_02_190
AHSG ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.12868 1 DataSet_02_193
AHSG ZFX siRNA Mammary_gland MCF7 0.3 -1.73697 0.75916 0.88268 DataSet_02_206
AHSG AR siRNA Prostate abl cells 0.626923 -0.67364 0.46467159921607 0.999852161656754 DataSet_03_004
AHSG ARID1A siRNA Mammary_gland MDA-MB-157 1.72429 0.785998 - - DataSet_03_014
AHSG ATF4 siRNA Skin A375 0.506425 -0.981578 0.0533703002088822 0.775512819201899 DataSet_03_018
AHSG GATA4 siRNA Stomach AGS 0.539276 -0.890904 0.23892811568181 0.842832540366852 DataSet_03_105
AHSG GATA6 siRNA Stomach AGS 0.601507 -0.733345 0.0215355665094708 0.377613516406955 DataSet_03_108
AHSG GATA6 siRNA Stomach KatoIII 1.79254 0.842009 0.114181823623131 0.639389979076894 DataSet_03_109
AHSG MEF2D shRNA Liver HuH7 0.489053 -1.03194 - - DataSet_03_162
AHSG MEF2D siRNA Liver HuH7 1.64492 0.718017 - - DataSet_03_163
AHSG MTA2 siRNA Stomach SGC-7901 0.556107 -0.846566 - - DataSet_03_169
AHSG MYB siRNA Cord_Blood CD34+ progenitor cells 0.193122 -2.37241 - - DataSet_03_170
AHSG MYC siRNA Colon HT29 0.254949 -1.97172 - - DataSet_03_177
AHSG SOX11 siRNA Lung_fibroblast NHLF 1.87551 0.907281 0.148418686119836 0.562370731433619 DataSet_03_237
AHSG SOX2 CRISPR Seminoma-like TCam-2 17.7997 4.15378 0.0778526913601919 0.999580851453413 DataSet_03_244
AHSG SOX2 siRNA Mammary_gland GSC-11 0.38675 -1.37053 1.3808759936363e-05 0.00299205532917935 DataSet_03_245
AHSG SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.9403 0.956279 - - DataSet_03_246
AHSG STAT1 knockout Liver Huh-7.5 0.630514 -0.6654 3.19114420497306e-05 0.00684252493171915 DataSet_03_257
AHSG STAT3 CRISPR Embryo hESC 3.53572 1.822 0.00536053395245954 0.0504696765643299 DataSet_03_258
AHSG STAT6 siRNA Umbilical_vein HUVEC 2.02222 1.01594 0.161776892384746 0.835278631521068 DataSet_03_264
AHSG APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 8.75 3.12928 0.00435911131023384 0.356485482249421 DataSet_04_001
AHSG EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.491803 -1.02385 0.543640127321074 0.78587476585451 DataSet_04_008
AHSG ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0952381 -3.39232 1.35457091271007e-05 0.0705648732380784 DataSet_04_009
AHSG FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.159868248290184 0.801001232267312 DataSet_04_011
AHSG SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 16.375 4.03342 0.00107954338287586 0.0979887211869635 DataSet_04_019
AHSG SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0952381 -3.39232 0.0273034010927264 0.395061837750111 DataSet_04_020
AHSG ANXA2 CRISPR Liver HepG2 13.875 3.79442 0.00304593477991885 0.461528344948158 DataSet_04_024
AHSG SMAD4 CRISPR Liver HepG2 0.512069 -0.96559 0.000409070212941403 0.0527443981287996 DataSet_04_035
AHSG ZC3H8 shRNA Liver HepG2 2.03458 1.02473 0.0021254332468997 0.0735572924512638 DataSet_04_040
AHSG CNOT7 CRISPR Liver HepG2 1.52445 0.608289 0.000196931669859064 0.0115756367231466 DataSet_04_045
AHSG PAN2 CRISPR Liver HepG2 0.512069 -0.96559 3.62524895903267e-05 0.0134929239906341 DataSet_04_066
AHSG ABT1 shRNA Liver HepG2 0.641999 -0.639357 0.00240933226427369 0.0140373327282483 DataSet_04_052
AHSG CNOT7 shRNA Liver HepG2 0.579999 -0.785878 0.00610891699075962 0.0205693957103618 DataSet_04_051
AHSG DDX1 shRNA Liver HepG2 1.62273 0.698423 0.000313953186146688 0.0429589673467077 DataSet_04_057
AHSG PRPF6 shRNA Liver HepG2 0.532771 -0.908411 0.00391456633623502 0.0526840986548604 DataSet_04_056
AHSG UBE2L3 shRNA Liver HepG2 1.7465 0.804465 0.000763845793981642 0.010312651276136 DataSet_04_055
AHSG YBX3 shRNA Liver HepG2 1.85007 0.887583 0.000148713215128219 0.0284930389263024 DataSet_02_98
AHSG ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.181818 -2.45943 0.321559057499814 0.531265145792209 DataSet_04_048
AHSG NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.478554460531201 0.667220195903734 DataSet_04_046
AHSG SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.795868909595498 0.956636905922333 DataSet_04_073
AHSG SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.66667 2.22239 0.299138510304191 0.464687588178177 DataSet_04_049
AHSG ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0588235 -4.08746 0.0432491077070255 0.122274263015631 DataSet_04_060
AHSG UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.695183915964789 0.868494137100788 DataSet_04_062
AHSG SMARCA4 siRNA Colon HCT116 1.67875 0.747386 1.890510e-02 0.1554389 DataSet_03_302
AHSG ELF3 CRISPR Bile_duct HBDEC2 0.621041 -0.687239 7.036810e-03 2.590781e-02 DataSet_03_304
AHSG ELF3 knockdown Bile_duct HBDEC2 0.665424 -0.587654 4.827598e-02 1.966715e-01 DataSet_03_305
AHSG HDAC5 siRNA Liver human hepatocytes 0.449884 -1.15237 3.689443e-06 2.298496e-04 DataSet_03_346
AHSG SNAI2 shRNA Pancreas KLM1 1.63097 0.705733 9.959943e-02 0.41250476 DataSet_03_307
AHSG ETV5 knockdown Colon HT29 2.4 1.26303 2.110958e-02 0.167893987 DataSet_03_353
AHSG PARP1 siRNA Prostate LNCaP 2.30164 1.20266 3.952228e-01 0.665528447 DataSet_03_354
AHSG TP53 knockout Stomach SNU1 0.0294098 -5.08756 0.2819436178 0.9301241 DataSet_03_365
AHSG USP22 shRNA Liver PLC_PRF_5 cells 0.535064 -0.902217 6.612615e-02 0.24492275 DataSet_03_368
AHSG BHLHE40 shRNA Cervix HeLaS3 2.66667 1.41504 7.197667e-01 0.95344806 DataSet_03_372
AHSG E2F1 siRNA Nasopharynx HK1 0.5 -1 2.247822e-01 8.707180e-01 DataSet_03_373
AHSG SMARCA2 shRNA Lung NCI-H1944 2.8209 1.49615 1.390819e-02 2.524734e-01 DataSet_03_377
AHSG TCF19 CRISPR Oral_squamous CAL27 0.43721 -1.1936 5.150513e-02 0.2172632423 DataSet_03_383
AHSG YY1 shRNA Brain GSC1517 0.375 -1.41504 - - DataSet_03_384
AHSG NFKBIA shRNA Bone_marrow U2OS 0.00880503 -6.82746 3.250450e-01 0.87005461 DataSet_03_389
AHSG KDM5A CRISPR Lung GLC16 1.65178 0.724024 5.905642e-01 0.735050208 DataSet_03_392
AHSG ASXL1 CRISPR Embryo iPSC 1.52713 0.610822 0.4110817551 0.8455453 DataSet_03_394
AHSG BMI1 shRNA Bile_duct QBC-939 2.65556 1.40902 5.988945e-04 0.0054867186 DataSet_03_395
AHSG SATB2 CRISPR Colon Colon organoid 2.25 1.16992 6.929757e-01 1.00000000 DataSet_03_406
AHSG CHD1 shRNA Prostate LNCaP 0.655172 -0.610053 4.391016e-02 4.507426e-01 DataSet_03_407
AHSG USP22 shRNA Liver HuH7 0.129614 -2.94771 - - DataSet_03_411
AHSG E2F6 shRNA Liver HuH7 0.366701 -1.44732 - - DataSet_03_412
AHSG E2F1 siRNA Prostate LNCaP 2.5 1.32193 7.845025e-02 0.6291071237 DataSet_03_413
AHSG ZKSCAN3 CRISPR Colon HCT116 2 1 4.052460e-02 0.394122782 DataSet_03_415
AHSG FOXK2 shRNA Ovary OVCAR-5 0.133333 -2.90689 1.529454e-03 0.08266460 DataSet_03_419
AHSG FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.285714 -1.80735 - - DataSet_03_422
AHSG MAEL CRISPR Liver Alexander cells 4.63327 2.21203 - - DataSet_03_423
AHSG POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2 1 3.381307e-01 0.574894029 DataSet_03_434
AHSG FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 8.88031 3.15061 3.504185e-02 0.72689181 DataSet_03_439
AHSG RELB CRISPR Colon SW480 4 2 1.179162e-01 3.014054e-01 DataSet_03_449
AHSG CBX2 siRNA Mammary_gland MCF7 0.472495 -1.08163 6.696748e-01 0.7993230470 DataSet_03_451
AHSG ARID1A shRNA Bile_duct MMNK1 0.216993 -2.20428 4.096051e-02 0.219658586 DataSet_03_458
AHSG PARP1 knockout Embryo_kidney HEK293a 1.5625 0.643856 1.185662e-01 2.288084e-01 DataSet_03_464
AHSG LIN28A siRNA Mammary_gland MCF7M 0.46398 -1.10786 3.347103e-01 0.7080276 DataSet_03_469
AHSG LIN28A siRNA Mammary_gland MCF7M 0.46398 -1.10786 3.347103e-01 0.7080276 DataSet_03_470
AHSG WHSC1 siRNA Prostate PC3 0.485714 -1.04182 6.500166e-02 0.23682146 DataSet_03_471
AHSG EZH2 siRNA Prostate LNCaP 0.345721 -1.53232 - - DataSet_03_472
AHSG CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.5262859 0.9520735 DataSet_04_071
AHSG APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 8.75 3.12928 0.06652644 0.485358 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate ERN1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of AHSG
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines