Gene Overview
| Target Gene: | Aldh1l1 |
| NCBI Official Symbol: | Aldh1l1 |
| Entrez ID: | 107747 |
| Ensembl ID: | ENSMUSG00000030088 |
| Gene Full Name: | aldehyde dehydrogenase 1 family, member L1 |
| Strand: | + |
| Gene Locus: | 6|6 D1 |
| External Links: |
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Aldh1l1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Aldh1l1
T(co)Fs
that Repress Aldh1l1
The Intensity of the Gene Regulated by T(co)Fs:
Aldh1l1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Aldh1l1 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 2.54217 | 1.34606 | 9.68012897706873e-05 | 0.00249524210397581 | DataSet_11_010 |
| Aldh1l1 | Batf2 | knockdown | Bone_marrow | Bone marrow-derived macrophages | 1.53274 | 0.616116 | 0.0037808608852039 | 0.018719514247906 | DataSet_11_012 |
| Aldh1l1 | Cebpb | knockout | Mammary_gland | Mammary epithlial cells (MECs) | 1.7411 | 0.8 | 0.0752548243839076 | 0.999788745984441 | DataSet_11_020 |
| Aldh1l1 | E2f4 | knockout | Brain | Forebrain | 1.75341 | 0.810164 | - | - | DataSet_11_033 |
| Aldh1l1 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.71981 | 0.782247 | 0.181326179571922 | 0.471525362399853 | DataSet_11_035 |
| Aldh1l1 | Gata2 | knockout | Kidney | renal collecting duct cells | 1.73946 | 0.798642 | - | - | DataSet_11_047 |
| Aldh1l1 | Gfi1 | knockout | Cord_Blood | T-cells | 2.13865 | 1.0967 | 0.174908758510553 | 0.583754301163915 | DataSet_11_053 |
| Aldh1l1 | Hsf4 | knockout | Eye | Lens | 0.532902 | -0.908058 | 0.386117276865642 | 0.987999303842427 | DataSet_11_058 |
| Aldh1l1 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 0.526316 | -0.925999 | 0.00329646842853623 | 0.491575278301074 | DataSet_11_064 |
| Aldh1l1 | Lhx8 | knockout | Gonads | Oocytes | 0.655805 | -0.608662 | 0.0684793211482289 | 0.993830266659981 | DataSet_11_069 |
| Aldh1l1 | Lhx8 | knockout | Ovary | Ovary | 0.661158 | -0.596932 | 0.0567648146220157 | 0.150943464112209 | DataSet_11_070 |
| Aldh1l1 | Lmx1b | knockout | Kidney | Kidney | 0.503057 | -0.991207 | 0.00386392222754366 | 0.119103611259292 | DataSet_11_072 |
| Aldh1l1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.55102 | -0.859822 | - | - | DataSet_11_074 |
| Aldh1l1 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 0.464844 | -1.10518 | 5.74528121780489e-05 | 0.00122848327565455 | DataSet_11_076 |
| Aldh1l1 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.485148 | -1.0435 | 0.0717436971272461 | 0.995635220774426 | DataSet_11_081 |
| Aldh1l1 | Neurod1 | knockout | Eye | Retina | 2.14289 | 1.09956 | 9.32818694506468e-05 | 0.00321923336817948 | DataSet_11_088 |
| Aldh1l1 | Neurod1 | knockout | Eye | Pineal gland | 1.50608 | 0.5908 | 0.145217844342993 | 0.9983937273602 | DataSet_11_089 |
| Aldh1l1 | Nhlh2 | knockout | Eye | Retina | 0.393123 | -1.34695 | 0.113555786559368 | 0.523726874680013 | DataSet_11_092 |
| Aldh1l1 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 1.68963 | 0.756711 | 0.0300171092520437 | 0.825846534822401 | DataSet_11_094 |
| Aldh1l1 | Nr2f2 | knockout | Ovary | E16.5 Ovary | 1.72712 | 0.788364 | 0.00790365295989206 | 0.244438149728177 | DataSet_11_095 |
| Aldh1l1 | Nrf1 | knockdown | Liver | Liver | 0.574515 | -0.799585 | 0.00217326311090822 | 0.0293255904678448 | DataSet_11_096 |
| Aldh1l1 | Otx2 | knockout | Brain | Ganglionic eminences and septum | 0.42499 | -1.2345 | 0.0160436506055119 | 0.386506128223696 | DataSet_11_098 |
| Aldh1l1 | Pitx2 | knockout | Eye | Cornea | 0.511188 | -0.968075 | 0.669357429518451 | 0.887055534988994 | DataSet_11_103 |
| Aldh1l1 | Prox1 | knockout | Liver | Liver | 0.307548 | -1.70112 | - | - | DataSet_11_109 |
| Aldh1l1 | Runx1 | knockout | Lymph | ProB cells | 5.51313 | 2.46287 | 0.000152765219389287 | 0.00745181350531432 | DataSet_11_116 |
| Aldh1l1 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.647216 | -0.627681 | 0.0188823507558171 | 0.999784944667092 | DataSet_11_117 |
| Aldh1l1 | Sall1 | knockout | Kidney | Kidney | 0.610719 | -0.71142 | 0.0513153793461954 | 0.757174298001747 | DataSet_11_122 |
| Aldh1l1 | Sall4 | shRNA | Embryo | ES cells | 0.609914 | -0.713323 | 0.2089228847504 | 0.999840995136314 | DataSet_11_123 |
| Aldh1l1 | Smad4 | siRNA | Brain | bEnd3 | 1.92349 | 0.943727 | - | - | DataSet_11_127 |
| Aldh1l1 | Smad4 | knockout | Aorta | Aortic arteries | 2.58365 | 1.36941 | 0.285539571805157 | 0.699894153418547 | DataSet_11_128 |
| Aldh1l1 | Sox11 | knockout | Eye | Retina | 1.70625 | 0.770829 | - | - | DataSet_11_137 |
| Aldh1l1 | Sox17 | siRNA | Embryo | NG4 | 2.28634 | 1.19304 | 0.00539165826750035 | 0.130033004797936 | DataSet_11_139 |
| Aldh1l1 | Stat3 | knockout | Lung | Lung typeII cells | 0.531561 | -0.911692 | 0.0406347978028831 | 0.66487364305402 | DataSet_11_151 |
| Aldh1l1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.617306 | -0.695942 | 0.0852455886936864 | 0.221369569938118 | DataSet_11_153 |
| Aldh1l1 | Tsc22d4 | shRNA | Liver | Liver | 1.53043 | 0.613937 | 0.00120031425854387 | 0.00895528896073092 | DataSet_11_169 |
| Aldh1l1 | Yy1 | knockout | Intestine | Jejunum crypt epithelium | 0.337469 | -1.56717 | 4.57095319406559e-05 | 0.00496666123672232 | DataSet_11_183 |
| Aldh1l1 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 0.198753 | -2.33096 | 0.00611214171881056 | 0.0521655653195755 | DataSet_11_185 |
| Aldh1l1 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 1.51843 | 0.602579 | 3.353606e-01 | 0.9999923 | DataSet_11_187 |
| Aldh1l1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 9.35135 | 3.22517 | - | - | DataSet_11_196 |
| Aldh1l1 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 0.0573995 | -4.12282 | - | - | DataSet_11_220 |
| Aldh1l1 | Dnmt3b | knockout | Heart | Cardiac ventricle | 2.69272 | 1.42906 | 3.605175e-16 | 1.112881e-11 | DataSet_11_205 |
| Aldh1l1 | Dux | siRNA | Embryo | ES cells | 1.66898 | 0.738968 | 1.411359e-01 | 0.8774371149 | DataSet_11_239 |
| Aldh1l1 | Ncl | siRNA | Embryo | ES cells | 2.09028 | 1.06369 | 1.947047e-02 | 0.2855180372 | DataSet_11_240 |
| Aldh1l1 | Dnmt3a | siRNA | Embryo | iPSC | 2.45052 | 1.29308 | - | - | DataSet_11_241 |
| Aldh1l1 | Twist1 | knockout | Bone_marrow | stromal cells | 3.20758e-19 | -61.4352 | - | - | DataSet_11_244 |
| Aldh1l1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 1.78864 | 0.838859 | 5.781140e-02 | 0.3191845160 | DataSet_11_245 |
| Aldh1l1 | Fubp1 | shRNA | Brain | brain neural progenitors | 2.10355 | 1.07283 | 0.5468079096 | 1 | DataSet_11_246 |
| Aldh1l1 | Dnmt1 | siRNA | Embryo | Embryo | 2.89474 | 1.53343 | - | - | DataSet_11_248 |
| Aldh1l1 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 74.947 | 6.2278 | 1.363245e-04 | 1.220669e-03 | DataSet_11_249 |
| Aldh1l1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 40.9881 | 5.35713 | 1.279834e-06 | 1.156491e-04 | DataSet_11_250 |
| Aldh1l1 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 1.72637 | 0.787742 | 9.507799e-04 | 0.022510665 | DataSet_11_252 |
| Aldh1l1 | Mecp2 | knockout | Adipose_tissue | inguinal adipose tissue | 0.55736 | -0.843319 | 4.868045e-04 | 0.1141779 | DataSet_11_254 |
| Aldh1l1 | Crebbp | shRNA | Lung | preSC | 0.552632 | -0.85561 | 1.021854e-01 | 0.55375919 | DataSet_11_255 |
| Aldh1l1 | Eed | knockout | Brain | Forebrain | 1.73389 | 0.794013 | 2.497524e-01 | 7.485151e-01 | DataSet_11_258 |
| Aldh1l1 | Fubp1 | shRNA | Bone_marrow | BM cells | 2.64865 | 1.40526 | 5.227103e-02 | 0.484806068 | DataSet_11_262 |
| Aldh1l1 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 1.88296 | 0.913001 | 9.590508e-02 | 0.30085902 | DataSet_11_267 |
| Aldh1l1 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 1.57907 | 0.65908 | 2.368902e-01 | 0.7396690 | DataSet_11_268 |
| Aldh1l1 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 1.72492 | 0.786529 | 2.384747e-01 | 0.6076680 | DataSet_11_271 |
| Aldh1l1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 3.17042 | 1.66467 | 7.804435e-01 | 0.98156410 | DataSet_11_272 |
| Aldh1l1 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 0.571429 | -0.807355 | 8.469727e-01 | 0.9961301 | DataSet_11_274 |
| Aldh1l1 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 1.84044 | 0.88005 | 1.582415e-01 | 0.5395938 | DataSet_11_284 |
| Aldh1l1 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 0.497483 | -1.00728 | 3.012383e-04 | 2.320642e-02 | DataSet_11_289 |
| Aldh1l1 | Kmt2d | CRISPR | Liver | MA1L | 0.598208 | -0.74128 | 4.147420e-05 | 1.972786e-03 | DataSet_11_290 |
| Aldh1l1 | Kmt2d | CRISPR | Liver | MA1L | 0.611495 | -0.709588 | 4.314978e-05 | 2.191165e-03 | DataSet_11_291 |
| Aldh1l1 | Setd1a | shRNA | Eye | Retina | 0.266292 | -1.90892 | 1.334990e-01 | 0.3230478818 | DataSet_11_293 |
| Aldh1l1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.86957 | 0.902703 | 6.253390e-01 | 8.641721e-01 | DataSet_11_297 |
| Aldh1l1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.515085 | -0.957119 | - | - | DataSet_11_305 |
| Aldh1l1 | Suz12 | knockout | Lung | Alveolar macrophage | 4.55945 | 2.18886 | 2.953943e-04 | 0.0265575900 | DataSet_11_311 |
| Aldh1l1 | Suz12 | knockout | Lung | Alveolar macrophage | 2.57001 | 1.36177 | 1.098563e-02 | 7.038365e-02 | DataSet_11_312 |
| Aldh1l1 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 5.85311 | 2.5492 | - | - | DataSet_11_313 |
| Aldh1l1 | Actl6a | knockout | Nerve | sciatic nerve | 0.618442 | -0.69329 | 2.495340e-02 | 0.219053788 | DataSet_11_314 |
| Aldh1l1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.0123762 | -6.33628 | 3.086503e-04 | 0.0260034351 | DataSet_11_317 |
| Aldh1l1 | Snai1 | knockdown | Heart | Heart | 0.651196 | -0.618837 | 1.392747e-03 | 0.02837142 | DataSet_11_326 |
| Aldh1l1 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 0.525994 | -0.926882 | 2.026953e-01 | 0.9609895 | DataSet_11_327 |
| Aldh1l1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 1.93112 | 0.949441 | 1.007793e-01 | 3.506952e-01 | DataSet_11_332 |
| Aldh1l1 | Ezh2 | knockout | Eye | Retina | 2.66359 | 1.41337 | 0.6623641522 | 1.0000000 | DataSet_11_334 |
| Aldh1l1 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 0.650664 | -0.620016 | - | - | DataSet_11_336 |
| Aldh1l1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.469091 | -1.09206 | 4.827987e-03 | 0.015381068 | DataSet_11_340 |
Regulation Region
Expression Atlas of Aldh1l1