Gene Overview
Target Gene: Anpep
NCBI Official Symbol: Anpep
Entrez ID: 16790
Ensembl ID: ENSMUSG00000039062
Gene Full Name: alanyl (membrane) aminopeptidase
Strand: -
Gene Locus: 7|7 D2
External Links:

Anpep Significantly Regulated by These T(co)Fs

T(co)Fs that Activate Anpep   
T(co)Fs that Repress Anpep
The Intensity of the Gene Regulated by T(co)Fs:
Anpep-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
Anpep Adnp knockout Embryo Whole embryonic body 1.98077 0.986061 0.234727786241891 0.592151560597958 DataSet_11_001
Anpep Atoh1 knockout Gastrointestinal_tissue Intestinal epithelial Lgr5(hi) stem cells 16.6958 4.06142 4.46003651765808e-06 0.00198480094441157 DataSet_11_010
Anpep Batf2 knockdown Bone_marrow Bone marrow-derived macrophages 0.616591 -0.697615 0.000196342256000151 0.00247224340052138 DataSet_11_012
Anpep Bcl11a knockout Bone_marrow Bone marrow erythoid progenitors 6.86333 2.77891 0.128480980787597 0.516774853724956 DataSet_11_013
Anpep Bhlha9 knockout Limb Whole limb bud 0.172312 -2.5369 - - DataSet_11_016
Anpep Cebpb shRNA Mammary_gland 4T1 mammary tumor cells 2.05486 1.03904 0.128483785703783 0.999984070881864 DataSet_11_022
Anpep Foxq1 siRNA Mammary_gland NM18 1.59427 0.672896 0.0415829118895048 0.146038827985965 DataSet_11_045
Anpep Gata2 knockout Kidney renal collecting duct cells 1.64514 0.71821 - - DataSet_11_047
Anpep Gfi1 knockout Macrophage_cells RAW264.7 0.207321 -2.27006 1.85451016698233e-07 2.4097184577147e-05 DataSet_11_052
Anpep Gfi1 knockout Cord_Blood T-cells 2.26562 1.17991 0.00124059056455315 0.0979916171383105 DataSet_11_053
Anpep Hnf1a knockout Intestine Jejunum 0.487962 -1.03516 7.95150540261699e-05 0.00998328696597763 DataSet_11_056
Anpep Hsf4 knockout Eye Lens 0.599661 -0.73778 0.248430217955481 0.987999303842427 DataSet_11_058
Anpep Irf6 knockout Skin Skin 1.50202 0.586908 0.048661866291669 0.278460480089694 DataSet_11_062
Anpep Junb shRNA Tibialis_anterior_muscle Tibialis anterior muscle 0.544895 -0.87595 0.0573392901425179 0.243665626301534 DataSet_11_065
Anpep Klf17 shRNA Mammary_gland 168FARN 0.1398 -2.83857 8.0235540817845e-06 0.00156554499304243 DataSet_11_066
Anpep Lmx1b knockout Kidney Kidney 0.199907 -2.3226 1.32641663911873e-05 0.00682409779478036 DataSet_11_072
Anpep Mef2a shRNA Muscle C2C12 0.632615 -0.6606 5.58257571569285e-06 0.000172694215230658 DataSet_11_077
Anpep Mef2b shRNA Muscle C2C12 0.629222 -0.668358 2.73135067961155e-06 0.000322515889699254 DataSet_11_078
Anpep Meis1 knockout Hematopoietic KSL hematopoietic cells 0.426009 -1.23104 0.0465898781333016 0.995635220774426 DataSet_11_081
Anpep Nhlh2 knockout Eye Retina 2.01852 1.0133 0.394864800971779 0.560630036058835 DataSet_11_092
Anpep Nr2f2 knockout Ovary E16.5 Ovary 1.90036 0.926271 0.134117123360668 0.527100207729376 DataSet_11_095
Anpep Otx2 knockout Eye Retina 1.77174 0.825166 0.347324953592858 0.999923528647439 DataSet_11_097
Anpep Pitx2 knockout Eye Cornea 0.458267 -1.12574 0.080785184948443 0.423953846304932 DataSet_11_103
Anpep Plagl2 knockout Intestine Small intestine 2.27988 1.18896 0.000282916670906437 0.0125932238032595 DataSet_11_104
Anpep Pparg siRNA Adipose_tissue Preadipocytes 2.04975 1.03545 0.319013558597169 0.971597954319947 DataSet_11_105
Anpep Rest knockout Brain Brain 3.0989 1.63176 0.0133305983935045 0.898578384859856 DataSet_11_113
Anpep Runx1 knockout Lymph ProB cells 1.58717 0.666457 0.0195430805920536 0.130150143712257 DataSet_11_116
Anpep Smad4 siRNA Brain bEnd3 23.1494 4.53291 - - DataSet_11_127
Anpep Smad4 knockout Aorta Aortic arteries 1.59332 0.672037 0.148971619872957 0.553601266278653 DataSet_11_128
Anpep Snai1 knockout Embryo Embryonic stem cells (ESCs) 0.426646 -1.22889 0.0178309671198206 0.999994003527217 DataSet_11_132
Anpep Sox11 knockout Eye Retina 0.555556 -0.847997 - - DataSet_11_137
Anpep Spdef knockout Colon Colon 0.00519264 -7.58932 0.111595380410578 0.997507742354799 DataSet_11_146
Anpep Srf knockout Aorta Aorta 1.94868 0.9625 0.00327112844033801 0.993526315825099 DataSet_11_148
Anpep Stat3 siRNA Macrophage_cells RAW264.7 1.84999 0.887514 0.000191008136097924 0.0670069945511245 DataSet_11_150
Anpep Stat6 knockout Bone_marrow Bone marrow-derived macrophages 0.551687 -0.858079 0.000614122072875348 0.00740122365688994 DataSet_11_153
Anpep Tet2 knockout Kidney Kidney 0.616859 -0.696988 0.369958444608972 1 DataSet_11_159
Anpep Vdr knockout Bone_marrow Bone marrow-derived macrophages 0.544195 -0.877803 0.150214314739943 0.999827445128963 DataSet_11_174
Anpep Vdr knockout Skin Skin 0.625844 -0.676126 - - DataSet_11_177
Anpep Xbp1 siRNA Liver Liver 2.1 1.07039 0.00251988704708172 0.0540701592856354 DataSet_11_181
Anpep Yy1 knockout Intestine Jejunum crypt epithelium 0.501179 -0.996602 0.00555066680743444 0.0347498883951095 DataSet_11_183
Anpep Dnmt1 siRNA Pituitary_gland AtT-20 1.51289 0.597306 8.303835e-01 0.9999923 DataSet_11_187
Anpep Cpeb1 siRNA Neuron Neuro-2a 0.257775 -1.95582 - - DataSet_11_189
Anpep Mapk9 knockout Hip Mouse Hip Cartilage 0.333328 -1.58499 1.060928e-04 7.680941e-04 DataSet_11_236
Anpep Kdm5b knockout Heart left ventricles 0.594686 -0.7498 0.5151775470 0.9999827 DataSet_11_210
Anpep Tet1 shRNA Embryo ES cells 1.89668 0.92348 6.075240e-09 2.727783e-06 DataSet_11_211
Anpep Tet1 shRNA Embryo ES cells 1.89668 0.92348 6.075240e-09 2.727783e-06 DataSet_11_212
Anpep Dnmt1 knockout Embryo Embryonic fibroblasts 0.604508 -0.726166 3.286132e-01 5.084483e-01 DataSet_11_192
Anpep Ezh2 knockdown Brain Brain 0.433835 -1.20478 8.232582e-03 0.0880566799 DataSet_11_221
Anpep Dnmt3a siRNA Peritoneum peritoneal macrophages 0.477628 -1.06604 - - DataSet_11_222
Anpep Smarca4 shRNA Embryo ES cells 0.218153 -2.19659 - - DataSet_11_224
Anpep Smarca4 shRNA Embryo ES cells 0.218153 -2.19659 - - DataSet_11_225
Anpep Dux siRNA Embryo ES cells 1.5325 0.61589 8.442998e-02 0.8376586364 DataSet_11_239
Anpep Lin28a knockout Heart Heart 0.623075 -0.682523 0.0924950643 0.8777652 DataSet_11_243
Anpep Twist1 knockout Bone_marrow stromal cells 0.0134422 -6.21709 - - DataSet_11_244
Anpep Fubp1 shRNA Brain brain neural progenitors 0.511215 -0.967998 0.6013897656 1 DataSet_11_246
Anpep Tet1 shRNA Muscle MLL-ENL-ERtm 2.29367 1.19766 5.549995e-03 1.614438e-02 DataSet_11_249
Anpep Kmt2d knockout Skin iBiP melanoma mouse model tumor cell 4.8253 2.27062 4.298841e-04 4.741247e-03 DataSet_11_250
Anpep Crebbp shRNA Lung preSC 0.4375 -1.19264 3.965914e-02 0.45795683 DataSet_11_255
Anpep Eed knockout Brain Forebrain 1.54925 0.631571 1.399133e-01 6.737631e-01 DataSet_11_258
Anpep Eed knockout Brain hindbrain 2.22181 1.15174 1.355644e-02 4.531313e-01 DataSet_11_259
Anpep Eed knockout Brain midbrain 1.68098 0.749299 1.348055e-02 4.043956e-01 DataSet_11_260
Anpep Fubp1 shRNA Bone_marrow BM cells 3.41667 1.77259 2.303183e-01 0.846117121 DataSet_11_262
Anpep Nr4a1 knockout Mammary_gland PyVT mouse mammary tumor cells 1.51215 0.5966 6.783210e-02 0.7273107 DataSet_11_268
Anpep Dux knockout Embryo Embryo 0.0169622 -5.88154 4.957844e-02 1.464102e-01 DataSet_11_269
Anpep Myc CRISPR Skeletal_muscle muscle stem cells 2.71259 1.43967 2.003427e-01 0.81420760 DataSet_11_272
Anpep Dux knockout Embryo Embryo 0.0169622 -5.88154 4.957838e-02 1.463957e-01 DataSet_11_273
Anpep Myod1 CRISPR Skeletal_muscle myoblast 4.93349 2.30261 2.411976e-08 2.136854e-06 DataSet_11_275
Anpep Ezh2 siRNA Bone_marrow Mesenchymal stem cells 0.245947 -2.02358 8.270710e-07 4.424579e-04 DataSet_11_276
Anpep Gsk3b CRISPR Neuron mPFC D2 neurons 0.375028 -1.41493 1.122098e-01 0.85266614 DataSet_11_277
Anpep Dnmt1 knockout Cortex mature Pvergic cortical interneurons 2.46512 1.30166 2.480834e-03 0.4964615 DataSet_11_283
Anpep Setd2 knockout Kidney primary renal tubular epithelial (RTE) cells 2.49231 1.31748 - - DataSet_11_285
Anpep Irf8 knockout Brain mice brain 0.439865 -1.18487 1.456593e-02 4.612695e-01 DataSet_11_292
Anpep Mkl1 knockout Bone_marrow Bone marrow differentiated macrophages 1.60807 0.685329 1.252456e-01 0.5031776963 DataSet_11_294
Anpep Sirt3 knockout Pancreatic_islets pancreatic beta cell 0.419179 -1.25436 1.199747e-04 9.894856e-03 DataSet_11_297
Anpep Phf8 knockout prostate Prostate 1.71055 0.77446 0.2742108102 0.5263303 DataSet_11_298
Anpep Brpf1 shRNA Nerve Neural progenitor cells 0.490932 -1.0264 6.363926e-01 0.9999903 DataSet_11_299
Anpep Arid2 knockout Muscle LSK 1.9561 0.967983 7.239417e-02 8.483798e-01 DataSet_11_301
Anpep Satb2 CRISPR Colon Colon organoid 2.04167 1.02975 6.361665e-02 0.6518149 DataSet_11_304
Anpep Myc CRISPR Skeletal_muscle quiescent muscle stem cell 26.6148 4.73416 3.668616e-01 0.80359421 DataSet_11_310
Anpep Suz12 knockout Lung Alveolar macrophage 2.00691 1.00498 2.134535e-02 0.2355606313 DataSet_11_311
Anpep Suz12 knockout Lung Alveolar macrophage 4.20879 2.0734 3.729235e-04 1.020088e-02 DataSet_11_312
Anpep Irf7 knockout Bone_marrow c-kit+ leukemic cells 2.23333 1.1592 - - DataSet_11_313
Anpep Satb2 knockout Colon Intestine epithelium 15.6944 3.97218 1.539391e-06 0.0010375495 DataSet_11_316
Anpep Arid1b knockout Bone_marrow bone marrow leukemia cells 0.208333 -2.26303 7.165668e-02 0.3624868240 DataSet_11_317
Anpep Arid2 knockout Bone_marrow bone marrow leukemia cells 0.047619 -4.39232 3.644584e-02 0.6531250 DataSet_11_318
Anpep Kat7 knockout Thymic_lobes Thymic epithelial cells 0.651249 -0.618719 1.757667e-01 4.824940e-01 DataSet_11_319
Anpep Kat7 knockout Thymic_lobes Thymic epithelial cells 2.43304 1.28276 1.319044e-01 3.278036e-01 DataSet_11_320
Anpep Gata2 knockout Brain Pituitary gland 0.62 -0.68966 0.908206104 1.0000000 DataSet_11_322
Anpep Setdb1 shRNA Neuron NE-4C 0.121936 -3.03581 - - DataSet_11_323
Anpep Padi2 knockout Testis Testis 0.662338 -0.594361 1.528184e-01 0.9481885 DataSet_11_324
Anpep Tet1 siRNA Embryo Embryonic fibroblasts 1.7885 0.838748 2.969891e-01 0.9609895 DataSet_11_327
Anpep Kdm5b siRNA Embryo ES cells 0.386635 -1.37095 0.2070565976 0.8933528 DataSet_11_331
Anpep Ezh2 shRNA Brain SVZ derived neural stem cells 0.326488 -1.6149 2.384799e-03 4.161458e-02 DataSet_11_332
Anpep Ezh2 knockout Eye Retina 0.414634 -1.27009 2.091456e-03 3.787808e-02 DataSet_11_333
Anpep Ezh2 knockout Eye Retina 0.125066 -2.99924 0.6944491862 1.0000000 DataSet_11_334
Anpep Dnmt3a knockout Peritoneum peritoneal macrophages 0.478282 -1.06407 - - DataSet_11_336
Anpep Dnmt3a siRNA Heart embryonic cardiomyocytes 0.506524 -0.981297 2.889603e-02 0.47939050 DataSet_11_337
Anpep Dnmt1 siRNA Heart embryonic cardiomyocytes 0.26809 -1.89921 2.822867e-04 0.009358970 DataSet_11_340
Anpep Ezh2 knockout Small_intestinal_crypts small intestinal crypts 6.50288 2.70108 0.0294265717 0.1712697 DataSet_11_341
Anpep Hnrnpk siRNA Embryo ES cells 0.653044 -0.614748 9.987804e-04 0.006998584 DataSet_11_342
Regulation Region
 
T(co)Fs that significantly regulate Spdef by the evidences of both expression and ChIP-seq/motif
Expression Atlas of Anpep
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)