Gene Overview
Target Gene: CORO2B
NCBI Official Symbol: CORO2B
Entrez ID: 10391
Ensembl ID: ENSG00000103647
Gene Full Name: coronin 2B
Strand: +
Gene Locus: 15q23
External Links:

CORO2B Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CORO2B   
T(co)Fs that Repress CORO2B
The Intensity of the Gene Regulated by T(co)Fs:
CORO2B-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CORO2B HNF1B shRNA Ovary RMG2 0.60168 -0.73293 0.004 0.01277 DataSet_01_103
CORO2B FOXO1 shRNA Bone EWS-FLI1 1.50075 0.58569 0.61093 0.96444 DataSet_01_106
CORO2B HSF1 siRNA Upper_aerodigestive_tract HSC3 0.48638 -1.03984 3.47496e-05 0.0202 DataSet_01_112
CORO2B GABPA siRNA Lung A549 2.21617 1.14807 3.30454e-07 4.72506e-06 DataSet_01_113
CORO2B ID1 siRNA Lung A549 2.07266 1.05148 0.01346 0.15392 DataSet_01_117
CORO2B FOXM1 siRNA Central_nervous_system U87 16.8637 4.07585 - - DataSet_01_122
CORO2B ID1 shRNA Neuroepithelium GSC2 1.93793 0.95452 1.99171e-11 5.09624e-10 DataSet_01_133
CORO2B STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.50688 -0.98028 0.27774 0.58775 DataSet_01_154
CORO2B ELK1 siRNA Peripheral_blood CD4+ T cells 2.00245 1.00177 0.00796 0.04404 DataSet_01_162
CORO2B GATA3 siRNA Peripheral_blood CD4+ T cells 1.98132 0.98646 0.00047 0.04301 DataSet_01_163
CORO2B NFKB1 siRNA Peripheral_blood CD4+ T cells 1.6772 0.74606 0.00816 0.26116 DataSet_01_167
CORO2B GABPA shRNA Prostate C4-2B 1446.89 10.4987 0.23874 0.43934 DataSet_01_190
CORO2B GABPA shRNA Prostate LNCaP 1001.37 9.96776 0.45976 0.7048 DataSet_01_191
CORO2B CREB1 shRNA Parotid_gland H3118 MEC 0.59957 -0.73801 0.21124 0.57514 DataSet_01_194
CORO2B CREB1 shRNA Parotid_gland HSY 3.62926 1.85967 0.0128 0.40367 DataSet_01_195
CORO2B TP63 siRNA Immortalized_keratinocyte HaCaT RG 7.53684 2.91396 - - DataSet_01_196
CORO2B TP63 siRNA Head_and_neck SCC-1 0.41948 -1.25334 - - DataSet_01_198
CORO2B TP63 siRNA Immortalized_keratinocyte HaCaT 0.59966 -0.73779 - - DataSet_01_200
CORO2B TP63 siRNA Head_and_neck SCC-012 0.64278 -0.63759 - - DataSet_01_201
CORO2B HIC1 shRNA Mammary_gland HBL100 2.13058 1.09125 - - DataSet_01_205
CORO2B MITF shRNA Skin COLO829 1.66822 0.73831 0.28073 0.4961 DataSet_01_207
CORO2B FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.49784 -1.00626 - - DataSet_01_208
CORO2B LIN28A siRNA Embryo H9 2.69372 1.4296 0.00014 0.00378 DataSet_01_215
CORO2B ARNT shRNA Embryo hESC HSF1 0.58628 -0.77035 0.20949 0.99999 DataSet_01_240
CORO2B EGR2 siRNA Muscle A673 1.91894 0.94031 0.11349 0.66484 DataSet_01_242
CORO2B EGR2 siRNA Neuroepithelium SK-N-MC 1.86951 0.90266 0.14136 0.76806 DataSet_01_243
CORO2B TWIST1 shRNA Stomach CAF14 0.60627 -0.72197 0.04449 0.99996 DataSet_01_252
CORO2B TWIST1 shRNA Stomach CAF32 0.35182 -1.5071 0.00029 0.01502 DataSet_01_253
CORO2B TWIST1 shRNA Stomach CAF 0.46184 -1.11454 0.01817 0.52717 DataSet_01_254
CORO2B SOX4 shRNA Mammary_gland MDA-MB-231 0.54327 -0.88026 0.00653 0.09775 DataSet_01_260
CORO2B ZIC5 siRNA Skin A375 1.80202 0.84961 - - DataSet_01_284
CORO2B ZIC5 siRNA Skin SK-MEL-28 1.95424 0.9666 - - DataSet_01_285
CORO2B POSTN shRNA Brain GSC272 0.52119 -0.94012 0.1678 0.58241 DataSet_01_293
CORO2B TFAP4 siRNA Brain BE(2)-C 0.12027 -3.05566 0.20492 0.51625 DataSet_01_295
CORO2B MYCN siRNA Brain BE(2)-C 3.78836 1.92157 0.49482 1 DataSet_01_296
CORO2B PTEN shRNA Skin A431 5.46527 2.45029 0.01599 0.1122 DataSet_01_301
CORO2B PTEN shRNA Lung HCC827 0.34947 -1.51678 0.19301 0.66584 DataSet_01_302
CORO2B PTEN shRNA Mammary_gland SKBR3 2.46621 1.3023 0.19243 0.67306 DataSet_01_303
CORO2B ETV5 siRNA Soft_tissue hADSC 1.61107 0.68802 0.00063 0.01508 DataSet_01_304
CORO2B SOX9 siRNA Prostate VCaP 0.40182 -1.31539 0.04557 0.9316 DataSet_01_308
CORO2B SOX9 siRNA Prostate VCaP 0.40182 -1.31539 0.04557 0.9316 DataSet_01_309
CORO2B OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 1.68952 0.75662 0.04184 0.30977 DataSet_01_313
CORO2B ELK3 shRNA Mammary_gland MDA-MB-231 0.64514 -0.63233 0.00091 0.0032 DataSet_01_318
CORO2B MYC siRNA Colon HCT116 1.893 0.92067 8.15519e-06 5.02807e-05 DataSet_01_324
CORO2B HIF1A siRNA Oral_cavity OEC-M1 1.88254 0.91268 0.29875 0.85205 DataSet_01_348
CORO2B GTF2B siRNA Cervix HeLa 0.60674 -0.72086 - - DataSet_01_362
CORO2B RBFOX2 shRNA Liver HepG2 1.73729 0.79684 0.10219 0.65168 DataSet_02_101
CORO2B HDGF shRNA Liver HepG2 2.28667 1.19325 0.00525 0.07843 DataSet_02_104
CORO2B U2AF2 shRNA Liver HepG2 0.43846 -1.18948 0.31377 0.46304 DataSet_02_105
CORO2B SSB shRNA Liver HepG2 0.00685 -7.18982 0.00013 0.00391 DataSet_02_107
CORO2B ZNF622 shRNA Liver HepG2 3.2069 1.68118 0.00038 0.00625 DataSet_02_108
CORO2B HNRNPUL1 shRNA Liver HepG2 0.42086 -1.24858 0.0169 0.0534 DataSet_02_109
CORO2B XRCC5 shRNA Liver HepG2 3.03846 1.60334 0.00373 0.12948 DataSet_02_114
CORO2B PCBP1 shRNA Liver HepG2 3.2 1.67807 0.09479 0.15056 DataSet_02_115
CORO2B TARDBP shRNA Liver HepG2 0.37685 -1.40792 0.00339 0.02306 DataSet_02_116
CORO2B SUB1 shRNA Liver HepG2 2.58462 1.36995 0.00382 0.12645 DataSet_02_117
CORO2B RBM25 shRNA Liver HepG2 9.06667 3.18057 0.01948 0.057 DataSet_02_119
CORO2B PTBP1 shRNA Liver HepG2 25.4667 4.67054 0.00712 0.01825 DataSet_02_120
CORO2B RBM34 shRNA Liver HepG2 0.54615 -0.87262 0.02562 0.39846 DataSet_02_121
CORO2B EWSR1 shRNA Liver HepG2 1.62 0.69599 0.01109 0.06387 DataSet_02_122
CORO2B FUS shRNA Liver HepG2 2.76923 1.46949 0.00387 0.06474 DataSet_02_124
CORO2B HNRNPLL shRNA Liver HepG2 0.18101 -2.46587 7e-04 0.01189 DataSet_02_125
CORO2B SNRNP70 shRNA Liver HepG2 0.26409 -1.92087 0.00624 0.04352 DataSet_02_126
CORO2B PRPF4 shRNA Liver HepG2 0.22162 -2.17383 0.00195 0.03079 DataSet_02_128
CORO2B ZFX siRNA Mammary_gland MCF7 0.51351 -0.96153 0.03921 0.17923 DataSet_02_206
CORO2B AR siRNA Prostate abl cells 5.38095 2.42786 0.131636697120133 0.999852161656754 DataSet_03_004
CORO2B ASCL1 siRNA Lung DMS79 0.575419 -0.797315 0.120754500404706 0.786293314348562 DataSet_03_016
CORO2B BCL6 siRNA Lymph Pfeiffer DLBCL 0.477314 -1.06699 0.0382120939013134 0.462643316122906 DataSet_03_026
CORO2B CEBPB siRNA Embryo hESC 2.94587 1.55869 0.0547101777002072 0.381538773020676 DataSet_03_049
CORO2B FOXM1 siRNA Aorta Vascular smooth muscle cells 1.59436 0.672975 - - DataSet_03_090
CORO2B FOXM1 siRNA Mammary_gland BT-20 cells 0.5 -1 0.104381592812916 0.5207873664479 DataSet_03_091
CORO2B GATA4 siRNA Stomach AGS 2.75129 1.46011 0.243258273946949 0.844680792640182 DataSet_03_105
CORO2B GATA4 siRNA Stomach YCC3 0.640831 -0.641984 0.257115303755875 0.766180253589305 DataSet_03_107
CORO2B GATA6 siRNA Stomach AGS 0.663673 -0.591457 0.546003829973952 0.883136254918966 DataSet_03_108
CORO2B GATA6 siRNA Stomach KatoIII 0.61748 -0.695535 0.197956108230158 0.707333259704245 DataSet_03_109
CORO2B HIF3A siRNA Liver Hep3B 1.57462 0.655 0.220268832041551 1 DataSet_03_120
CORO2B HIF3A siRNA Liver Hep3B 1.57462 0.655 0.220268832041551 1 DataSet_03_121
CORO2B HINFP siRNA Bone_marrow U2OS 1.61444 0.691031 0.000589899665890625 0.0213676869297396 DataSet_03_123
CORO2B JARID1A siRNA Brain NB1691 1.51068 0.595194 0.0312035648685104 0.482531830811863 DataSet_03_136
CORO2B KLF5 siRNA Stomach AGS 2.53103 1.33973 0.167734083792704 0.648960120936423 DataSet_03_149
CORO2B KLF5 siRNA Stomach KatoIII 0.518855 -0.946596 0.412784666807741 0.789864111136583 DataSet_03_150
CORO2B KLF5 siRNA Stomach YCC3 0.439684 -1.18546 0.273484530372434 0.638937048787901 DataSet_03_151
CORO2B MYB siRNA Cord_Blood CD34+ progenitor cells 19.7653 4.3049 - - DataSet_03_170
CORO2B MYC siRNA Colon HT29 3.80787 1.92898 - - DataSet_03_177
CORO2B MYC siRNA Central_nervous_system DAOY M2.1 2.7703 1.47004 1.68460714757132e-06 1.19921656083685e-05 DataSet_03_178
CORO2B MYCN siRNA Brain NB1691 1.77463 0.827521 0.0214137308661662 0.427431841231722 DataSet_03_186
CORO2B NR2F2 siRNA Uterus Primary eutopic stromal cells 0.542524 -0.882242 0.0705231932113539 0.99947668859931 DataSet_03_202
CORO2B PHB shRNA Embryo Embryonic stem cells (ESCs) 2.98795 1.57915 0.00494984963655861 0.0182698131719238 DataSet_03_211
CORO2B SOX11 siRNA Lung_fibroblast NHLF 0.64403 -0.6348 0.0296980922655815 0.346727495210233 DataSet_03_237
CORO2B SOX11 siRNA Lung_fibroblast NHLF 0.531249 -0.912539 0.0114468064047197 0.206655365837802 DataSet_03_238
CORO2B SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 3.33333 1.73697 - - DataSet_03_246
CORO2B SP1 siRNA Mammary_gland MDA-MB-231 0.45973 -1.12114 0.168203696265594 0.413972819854456 DataSet_03_250
CORO2B STAT3 CRISPR Embryo hESC 6.53011 2.70711 0.0224862938707006 0.0869784560567604 DataSet_03_258
CORO2B STAT3 siRNA Prostate DU145 2.16415 1.1138 0.000145162729812526 0.0110686581482051 DataSet_03_260
CORO2B STAT6 siRNA Umbilical_vein HUVEC 1.708 0.772308 0.287995995547217 0.870695740656481 DataSet_03_264
CORO2B TFAP2C siRNA Mammary_gland MCF7 0.417054 -1.2617 0.628246103030825 0.83736501268742 DataSet_03_274
CORO2B TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.605749 -0.723207 0.313508018538507 0.999791649573014 DataSet_03_278
CORO2B ERN1 CRISPR Liver HepG2 0.427451 -1.22617 0.000568338967735045 0.0458543944154898 DataSet_04_029
CORO2B NFX1 CRISPR Liver HepG2 1.50602 0.590745 0.014362778364178 0.0449111288524138 DataSet_04_032
CORO2B PAN2 CRISPR Liver HepG2 1.6 0.678072 0.0476118890818453 0.18034372399379 DataSet_04_033
CORO2B SMAD4 CRISPR Liver HepG2 1.61258 0.689367 0.00567842958884377 0.0816678591542776 DataSet_04_035
CORO2B YBX1 CRISPR Liver HepG2 0.0961538 -3.37851 0.0352332448638412 0.972884761036538 DataSet_04_039
CORO2B ZC3H8 shRNA Liver HepG2 0.26506 -1.91561 0.00479378915703955 0.0853116958887745 DataSet_04_040
CORO2B CNOT7 CRISPR Liver HepG2 0.5 -1 0.000492314380214266 0.013613363560152 DataSet_04_045
CORO2B PAN2 CRISPR Liver HepG2 1.61258 0.689367 0.00172878300251939 0.0309206969477056 DataSet_04_066
CORO2B ABT1 shRNA Liver HepG2 1.64458 0.717718 0.00813252083530725 0.0304369121698549 DataSet_04_052
CORO2B CALR shRNA Liver HepG2 1.63087 0.705644 0.0151143704963518 0.0486357981373288 DataSet_04_053
CORO2B CCAR1 shRNA Liver HepG2 1.69057 0.757506 0.00301669030351603 0.0259128730438027 DataSet_04_054
CORO2B CNOT7 shRNA Liver HepG2 0.492891 -1.02066 0.00745940454389775 0.0235450667569006 DataSet_04_051
CORO2B DDX1 shRNA Liver HepG2 2.40072 1.26347 0.0172151424652465 0.129293785344743 DataSet_04_057
CORO2B UBE2L3 shRNA Liver HepG2 2.09524 1.06711 0.00137263117778338 0.0132624831106158 DataSet_04_055
CORO2B YBX3 shRNA Liver HepG2 0.476534 -1.06935 0.0118362792118915 0.0833493985339682 DataSet_02_98
CORO2B HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.828796719433377 0.959711480173343 DataSet_02_75
CORO2B CNOT3 shRNA Lung A549 3.94399 1.97966 1.384667e-01 0.8830540 DataSet_03_340
CORO2B ZNF598 knockout Cervix HeLa 1.69368 0.760159 1.156680e-02 1.0000000 DataSet_03_299
CORO2B SMARCA4 siRNA Colon HCT116 1.592 0.670842 2.167422e-01 9.892536e-01 DataSet_03_301
CORO2B ELF3 CRISPR Bile_duct HBDEC2 0.390706 -1.35585 1.262226e-04 1.409553e-03 DataSet_03_304
CORO2B ELF3 knockdown Bile_duct HBDEC2 0.620261 -0.689052 1.462818e-01 2.812563e-01 DataSet_03_305
CORO2B ACTR5 siRNA Muscle RD 2.98221 1.57638 - - DataSet_03_343
CORO2B INO80 siRNA Muscle RD 1.87671 0.908203 - - DataSet_03_344
CORO2B BRCA1 siRNA Mammary_gland MCF7 0.52181 -0.938404 1.998658e-01 0.9999931 DataSet_03_308
CORO2B EZH2 knockdown Colon HCT116 4.37122 2.12804 0.051921325 0.8488990 DataSet_03_334
CORO2B ESR1 siRNA Mammary_gland MCF7 1.81455 0.859614 4.989305e-03 0.0452326967 DataSet_03_352
CORO2B ETV5 knockdown Colon HT29 1.61111 0.688056 2.783952e-01 0.527308910 DataSet_03_353
CORO2B TET1 CRISPR Mammary_gland Hs578T 0.53529 -0.901606 2.965203e-01 4.933447e-01 DataSet_03_355
CORO2B PTPN14 CRISPR Brain U5-NPC 0.362121 -1.46546 6.273882e-02 0.28606593 DataSet_03_357
CORO2B EP300 shRNA Mammary_gland MCF10AT 8.53846 3.09398 5.973329e-03 0.054485123 DataSet_03_364
CORO2B TP53 knockout Stomach SNU1 2.27798 1.18775 0.9329353146 1.0000000 DataSet_03_365
CORO2B ZNF148 shRNA Mammary_gland MDA-MB-231 0.571259 -0.807783 1.801026e-03 0.035044686 DataSet_03_366
CORO2B DNMT3A knockout Embryo_kidney HEK293T 7.34829 2.87741 - - DataSet_03_369
CORO2B ZFP36L1 siRNA Urinary_bladder J82 2.45602 1.29632 - - DataSet_03_371
CORO2B HNRNPU siRNA Colon RKO 0.60813 -0.717548 - - DataSet_03_374
CORO2B GLI1 siRNA Skeletal_muscle RMS13 3.75908 1.91038 2.402490e-01 0.471856524 DataSet_03_375
CORO2B ZNF213 siRNA Mammary_gland MCF7 1.76285 0.817906 6.059053e-01 8.009522e-01 DataSet_03_376
CORO2B EZH2 CRISPR Ovary SKOV3 0.35443 -1.49643 6.584603e-02 0.2241062253 DataSet_03_378
CORO2B DDX5 shRNA Stomach HGC-27 3.9 1.96347 - - DataSet_03_379
CORO2B TCF19 CRISPR Oral_squamous CAL27 2.72261 1.44499 1.542869e-02 0.0994725502 DataSet_03_383
CORO2B YY1 shRNA Brain GSC1517 1.56849 0.649375 - - DataSet_03_384
CORO2B NFKBIA shRNA Bone_marrow U2OS 0.641319 -0.640886 4.287854e-02 0.87005461 DataSet_03_389
CORO2B YY1 knockdown Liver HepG2 29.75 4.89482 3.321843e-12 3.586088e-10 DataSet_03_390
CORO2B KDM5A CRISPR Lung GLC16 0.62342 -0.681722 2.884483e-03 0.023694480 DataSet_03_392
CORO2B ASXL1 CRISPR Embryo iPSC 2.39421 1.25955 0.2856091618 0.8217350 DataSet_03_394
CORO2B EHF shRNA Stomach MKN7 0.0122508 -6.35099 - - DataSet_03_402
CORO2B JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.50916 0.593746 4.102100e-02 0.3239928 DataSet_03_403
CORO2B CDK7 shRNA Bone_marrow D458 0.618848 -0.692343 1.118756e-01 0.41900299 DataSet_03_404
CORO2B MAP3K7 shRNA Prostate LNCaP 0.409091 -1.28951 5.013208e-02 2.070363e-01 DataSet_03_408
CORO2B STRAP knockout Nerve SK-N-AS 1.90284 0.92815 - - DataSet_03_409
CORO2B SIRT1 siRNA Pancreas PANC1 0.392857 -1.34792 4.079881e-01 0.575429754 DataSet_03_410
CORO2B FOXK2 shRNA Ovary OVCAR-5 1.82895 0.871014 4.988662e-02 0.18273523 DataSet_03_419
CORO2B MAEL CRISPR Liver Alexander cells 0.0769231 -3.70044 - - DataSet_03_423
CORO2B LHX2 shRNA Bone_marrow ES-derived RPE cells 3.03038 1.5995 2.758690e-02 1.000000e+00 DataSet_03_428
CORO2B USP7 shRNA Skin xenograft cells 0.518355 -0.947988 0.27160485 0.4348960 DataSet_03_431
CORO2B PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.642857 -0.63743 - - DataSet_03_432
CORO2B NFE2L1 knockout Lung A549 1.64145 0.71497 4.084301e-01 9.984904e-01 DataSet_03_433
CORO2B FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 2.34083 1.22702 1.758414e-01 0.90558273 DataSet_03_439
CORO2B SETDB1 shRNA Colon HCT116 3.7706 1.91479 - - DataSet_03_440
CORO2B HMG20A siRNA Mammary_gland MDA-MB-231 0.475264 -1.0732 0.0308376079 0.2105526 DataSet_03_442
CORO2B FOSL1 siRNA Prostate MSKPCa3 0.385417 -1.37551 0.0099958343 0.3072825 DataSet_03_445
CORO2B RELB CRISPR Colon SW480 0.53401 -0.905061 1.162945e-02 8.513113e-02 DataSet_03_449
CORO2B CBX2 siRNA Mammary_gland MCF7 0.241895 -2.04755 1.667352e-01 0.2872123511 DataSet_03_451
CORO2B OGT siRNA Embryo BeWo cells 2 1 5.826027e-01 0.84740396 DataSet_03_453
CORO2B STAT3 shRNA Liver HepG2 5 2.32193 1.740387e-01 0.5673804397 DataSet_03_465
CORO2B SMARCA1 Cas13 Embryo_kidney HEK293T 0.495238 -1.01381 - - DataSet_03_466
CORO2B SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.55238 0.634483 - - DataSet_03_467
CORO2B CREBBP CRISPR Lymph U2932 1.7561 0.812373 1.216823e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate YBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CORO2B
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines