Gene Overview
Target Gene: CTTNBP2
NCBI Official Symbol: CTTNBP2
Entrez ID: 83992
Ensembl ID: ENSG00000077063
Gene Full Name: cortactin binding protein 2
Strand: -
Gene Locus: 7q31.31
External Links:

CTTNBP2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CTTNBP2   
T(co)Fs that Repress CTTNBP2
The Intensity of the Gene Regulated by T(co)Fs:
CTTNBP2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CTTNBP2 IRF2 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.25548 1.17343 0.01306 0.16434 DataSet_01_100
CTTNBP2 IRF6 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.98775 0.99113 0.0092 0.06916 DataSet_01_101
CTTNBP2 MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 3.26637 1.70769 1.76576e-07 3.59457e-06 DataSet_01_102
CTTNBP2 HNF1B shRNA Ovary RMG2 0.64481 -0.63306 2.67388e-05 0.00021 DataSet_01_103
CTTNBP2 HOXA1 siRNA Lung_fibroblast IMR-90 1.52117 0.60518 0.37802 0.65069 DataSet_01_110
CTTNBP2 ID1 siRNA Lung A549 1.67534 0.74445 0.06594 0.26405 DataSet_01_117
CTTNBP2 ID1 siRNA Lung H1650 0.42006 -1.25132 0.48073 0.76348 DataSet_01_118
CTTNBP2 ZIC2 siRNA Pancreas PANC1 1.52135 0.60535 - - DataSet_01_121
CTTNBP2 FOXM1 siRNA Central_nervous_system U87 2.91744 1.5447 - - DataSet_01_122
CTTNBP2 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.6507 0.72308 0.13561 0.95851 DataSet_01_137
CTTNBP2 NR3C1 siRNA Uterus Endometrial stromal cells 0.63069 -0.665 0.41252 0.99972 DataSet_01_141
CTTNBP2 STAT1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 0.35772 -1.48311 0.05159 0.2731 DataSet_01_154
CTTNBP2 HSF1 shRNA Skin A375 1.51134 0.59582 0.38381 0.6437 DataSet_01_155
CTTNBP2 GATA2 siRNA Prostate LNCaP 0.39947 -1.32383 6.06699e-05 0.00073 DataSet_01_193
CTTNBP2 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.15 -2.73697 - - DataSet_01_197
CTTNBP2 TP63 siRNA Head_and_neck SCC-1 7.07368 2.82246 - - DataSet_01_199
CTTNBP2 TP63 siRNA Immortalized_keratinocyte HaCaT 2.35 1.23266 - - DataSet_01_200
CTTNBP2 TP63 siRNA Head_and_neck SCC-012 1.53846 0.62149 - - DataSet_01_201
CTTNBP2 TP63 siRNA Head_and_neck SCC-6 5.125 2.35755 - - DataSet_01_202
CTTNBP2 MITF shRNA Skin COLO829 0.57124 -0.80784 0.00325 0.0453 DataSet_01_207
CTTNBP2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 6.11762 2.61297 - - DataSet_01_209
CTTNBP2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.20568 -2.28152 - - DataSet_01_210
CTTNBP2 REST siRNA Prostate LNCaP 0.45397 -1.13932 0.00966 0.17107 DataSet_01_211
CTTNBP2 LIN28A siRNA Embryo H9 1.55862 0.64027 0.06057 0.15647 DataSet_01_215
CTTNBP2 KLF2 shRNA Bone_marrow RPMI8226 1.97951 0.98514 0.54994 0.91654 DataSet_01_226
CTTNBP2 TLX1 siRNA Haematopoietic_and_lymphoid_tissue ALLSIL 0.56982 -0.81143 0.00581 0.14321 DataSet_01_246
CTTNBP2 TWIST1 shRNA Stomach CAF32 0.32105 -1.63913 0.00583 0.0388 DataSet_01_253
CTTNBP2 TWIST1 shRNA Stomach CAF 0.58951 -0.76242 0.18038 0.6586 DataSet_01_254
CTTNBP2 MSX1 siRNA Tooth Dental Pulp Cells 0.40748 -1.29521 2.2508e-06 0.00011 DataSet_01_281
CTTNBP2 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.6254 -0.67715 0.00066 0.00686 DataSet_01_283
CTTNBP2 POSTN shRNA Brain GSC272 1.50446 0.58925 0.50651 0.76939 DataSet_01_293
CTTNBP2 TFAP4 siRNA Brain BE(2)-C 0.09448 -3.40383 0.17275 0.51625 DataSet_01_295
CTTNBP2 PTEN shRNA Lung HCC827 0.36975 -1.43537 0.18214 0.65906 DataSet_01_302
CTTNBP2 PTEN shRNA Mammary_gland SKBR3 0.34674 -1.52807 0.09621 0.60447 DataSet_01_303
CTTNBP2 SOX9 siRNA Prostate VCaP 0.58706 -0.76842 0.15801 0.9316 DataSet_01_308
CTTNBP2 SOX9 siRNA Prostate VCaP 0.58706 -0.76842 0.15801 0.9316 DataSet_01_309
CTTNBP2 ELK3 shRNA Mammary_gland MDA-MB-231 13.5383 3.75897 2.54877e-08 6.69286e-06 DataSet_01_318
CTTNBP2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.04545 -4.45943 0.01147 0.19424 DataSet_02_149
CTTNBP2 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.05556 -4.16993 0.44912 0.7236 DataSet_02_152
CTTNBP2 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.08995 0.4085 DataSet_02_154
CTTNBP2 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.09341 0.92135 DataSet_02_157
CTTNBP2 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.35897 -1.47805 0.31183 1 DataSet_02_190
CTTNBP2 AR siRNA Prostate abl cells 0.270588 -1.88583 0.172165295994989 0.999852161656754 DataSet_03_004
CTTNBP2 ARID1A siRNA Mammary_gland MDA-MB-157 0.28975 -1.78712 - - DataSet_03_014
CTTNBP2 BCL6 siRNA Lymph OCI-Ly7 DLBCL 1.9317 0.94987 0.38146904486249 0.87550011478965 DataSet_03_025
CTTNBP2 BCL6 siRNA Lymph Pfeiffer DLBCL 1.61351 0.690204 0.51950340511139 0.850765617487921 DataSet_03_026
CTTNBP2 CTCF siRNA Prostate LNCaP 1.8333 0.874441 0.0120262298558577 0.284443544833743 DataSet_03_056
CTTNBP2 GATA4 siRNA Stomach AGS 0.665723 -0.587007 0.31167956307769 0.872967240458663 DataSet_03_105
CTTNBP2 GATA4 siRNA Stomach KatoIII 0.353015 -1.5022 0.0758129367077132 0.881974118394822 DataSet_03_106
CTTNBP2 GATA4 siRNA Stomach YCC3 1.77328 0.826421 0.00468448449248375 0.429841151206507 DataSet_03_107
CTTNBP2 GATA6 siRNA Stomach AGS 0.644966 -0.632704 0.169026582663403 0.671846998673848 DataSet_03_108
CTTNBP2 GATA6 siRNA Stomach KatoIII 4.29477 2.10258 0.0247653943546666 0.475017373560943 DataSet_03_109
CTTNBP2 HNF4a siRNA Liver HepG2 0.486486 -1.03953 0.309636723356551 0.859123716068413 DataSet_03_126
CTTNBP2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.564331 -0.825386 0.512775953257211 0.999948959532916 DataSet_03_134
CTTNBP2 KLF5 siRNA Stomach KatoIII 3.31749 1.73009 0.092761287770675 0.528008747572935 DataSet_03_150
CTTNBP2 KLF5 siRNA Stomach YCC3 2.08453 1.05972 0.00339961918321139 0.0971223659794759 DataSet_03_151
CTTNBP2 MEF2D shRNA Liver HuH7 1.68782 0.755165 - - DataSet_03_162
CTTNBP2 MEF2D siRNA Liver HuH7 1.89554 0.922606 - - DataSet_03_163
CTTNBP2 MITF siRNA Skin Ma-Mel-15 0.650261 -0.620909 0.154734236312907 0.608792164331841 DataSet_03_166
CTTNBP2 MYC siRNA Colon HT29 11.5541 3.53034 - - DataSet_03_177
CTTNBP2 SOX11 siRNA Lung_fibroblast NHLF 1.51755 0.601744 0.0740705315730263 0.3860407553813 DataSet_03_238
CTTNBP2 SOX2 siRNA Mammary_gland GSC-11 1.52825 0.611884 7.61494913188397e-07 0.00125699112944631 DataSet_03_245
CTTNBP2 SP1 siRNA Mammary_gland MDA-MB-231 0.475664 -1.07199 0.135679295006458 0.413972819854456 DataSet_03_250
CTTNBP2 SP1 siRNA Ovary OVSAYO 2.4628 1.3003 0.0705279753178304 0.325281874019578 DataSet_03_251
CTTNBP2 STAT3 CRISPR Embryo hESC 3.52648 1.81823 0.0539463267599861 0.129587940849905 DataSet_03_258
CTTNBP2 STAT6 siRNA Umbilical_vein HUVEC 2.02609 1.0187 0.173081447321524 0.837635960915423 DataSet_03_264
CTTNBP2 TFAP2C siRNA Mammary_gland MCF7 0.450152 -1.15152 0.880644957282731 0.956626589779751 DataSet_03_274
CTTNBP2 TFE3 siRNA Kidney UOK257-2 1.94235 0.957804 - - DataSet_03_275
CTTNBP2 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.58377 0.663367 0.136880037916147 0.744769996513129 DataSet_03_282
CTTNBP2 ZNF165 siRNA Mammary_gland SUM159 0.585743 -0.771659 0.166759206437698 0.999998167536832 DataSet_03_288
CTTNBP2 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.410256 -1.2854 0.227566564343617 0.493792026967294 DataSet_02_38
CTTNBP2 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.102564 -3.2854 0.0317615551583458 0.0858497278741855 DataSet_02_14
CTTNBP2 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.102564 -3.2854 0.0509431256327265 0.133237194288201 DataSet_02_34
CTTNBP2 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.371127393385262 0.727801981464839 DataSet_02_75
CTTNBP2 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.487179 -1.03747 0.243142192541787 0.406941935388049 DataSet_02_35
CTTNBP2 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.0769231 -3.70044 0.0424760260719764 0.124925172265047 DataSet_02_43
CTTNBP2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.102564 -3.2854 0.0362194146548168 0.0882472735554189 DataSet_02_33
CTTNBP2 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.564103 -0.825971 0.391452846643633 0.561907229392204 DataSet_02_53
CTTNBP2 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.637668108301256 0.754923067506192 DataSet_04_059
CTTNBP2 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.938905012139921 0.991541782545828 DataSet_04_065
CTTNBP2 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.784695453764227 0.915173844200149 DataSet_04_062
CTTNBP2 AEBP1 siRNA Umbilical_vein HUVEC 2.15775 1.10953 7.884018e-02 0.563238092 DataSet_03_300
CTTNBP2 SMARCA4 siRNA Colon HCT116 1.60694 0.684314 2.066443e-01 9.892536e-01 DataSet_03_301
CTTNBP2 ELF3 CRISPR Bile_duct HBDEC2 9.87705 3.30408 1.230785e-05 3.769416e-04 DataSet_03_304
CTTNBP2 HDAC4 siRNA Liver human hepatocytes 1.65382 0.7258 2.843954e-03 4.291298e-02 DataSet_03_345
CTTNBP2 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.439905 -1.18474 2.833973e-01 0.6510154 DataSet_03_306
CTTNBP2 ACTR5 siRNA Muscle RD 1.64298 0.716319 - - DataSet_03_343
CTTNBP2 ARID3B CRISPR Colon HCT15 0.612296 -0.7077 - - DataSet_03_335
CTTNBP2 ESR1 siRNA Mammary_gland MCF7 1.78784 0.838216 9.932002e-02 0.2743689946 DataSet_03_352
CTTNBP2 PARP1 siRNA Prostate LNCaP 3.13991 1.65072 6.404591e-02 0.293311030 DataSet_03_354
CTTNBP2 TET1 CRISPR Mammary_gland Hs578T 5.47314 2.45237 6.243722e-01 7.799779e-01 DataSet_03_355
CTTNBP2 NCOA2 siRNA Uterus endometrial stromal cells 0.660377 -0.598637 0.2958312961 1 DataSet_03_360
CTTNBP2 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.661498 -0.596191 2.753753e-04 1.251467e-03 DataSet_03_362
CTTNBP2 ABL1 shRNA Liver HuH7 1.7113 0.775091 4.377445e-05 0.0011492829 DataSet_03_367
CTTNBP2 USP22 shRNA Liver PLC_PRF_5 cells 3.04167 1.60486 4.744246e-03 0.09002768 DataSet_03_368
CTTNBP2 E2F1 siRNA Nasopharynx HK1 0.5 -1 9.653467e-02 5.438761e-01 DataSet_03_373
CTTNBP2 ZNF213 siRNA Mammary_gland MCF7 0.531861 -0.910878 5.371019e-01 7.509795e-01 DataSet_03_376
CTTNBP2 EZH2 CRISPR Ovary SKOV3 1.69231 0.758992 4.929349e-02 0.1922712286 DataSet_03_378
CTTNBP2 DDX5 shRNA Stomach HGC-27 0.556901 -0.844508 - - DataSet_03_379
CTTNBP2 TCF19 CRISPR Oral_squamous CAL27 1.66845 0.738508 1.350213e-01 0.3945011409 DataSet_03_383
CTTNBP2 NFKBIA shRNA Bone_marrow U2OS 0.283368 -1.81925 5.916542e-01 0.87005461 DataSet_03_389
CTTNBP2 PRDM15 CRISPR Kidney Immortalized human podocytes 13.2095 3.72351 3.152708e-02 9.905467e-02 DataSet_03_391
CTTNBP2 ILF2 siRNA Stomach SGC-7901 0.375 -1.41504 0.4849176855 0.66041517 DataSet_03_393
CTTNBP2 ASXL1 CRISPR Embryo iPSC 0.530711 -0.914001 0.0275617299 0.8048302 DataSet_03_394
CTTNBP2 HMGA1 shRNA Bile_duct HUCCT1 6.83333 2.77259 4.024506e-02 0.240639024 DataSet_03_400
CTTNBP2 TFAP2A knockout Embryo H9 0.664316 -0.590058 6.865267e-03 0.05620259 DataSet_03_405
CTTNBP2 CHD1 shRNA Prostate LNCaP 0.411914 -1.27959 3.912407e-04 3.419558e-02 DataSet_03_407
CTTNBP2 E2F2 siRNA Prostate LNCaP 0.545455 -0.874469 1.357862e-01 3.539459e-01 DataSet_03_414
CTTNBP2 FOXQ1 CRISPR Lymph Primary CD4+ T cells 2 1 - - DataSet_03_422
CTTNBP2 MAEL CRISPR Liver Alexander cells 0.625 -0.678072 - - DataSet_03_423
CTTNBP2 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.618487 -0.693184 2.735828e-01 1.000000e+00 DataSet_03_428
CTTNBP2 USP7 shRNA Skin xenograft cells 0.354234 -1.49722 0.28016100 0.4350410 DataSet_03_431
CTTNBP2 NFE2L1 knockout Lung A549 1.91871 0.940134 4.770961e-01 9.984904e-01 DataSet_03_433
CTTNBP2 SUFU shRNA Mammary_gland HCC1954 cells 2 1 0.5986987362 0.8339612 DataSet_03_437
CTTNBP2 CIC knockout Brain Immortalized Astrocyte Cells 2.45606 1.29634 1.012720e-03 5.827319e-02 DataSet_03_438
CTTNBP2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.267327 -1.90332 5.803475e-03 0.40338377 DataSet_03_439
CTTNBP2 SETDB1 shRNA Colon HCT116 0.576846 -0.793741 - - DataSet_03_440
CTTNBP2 HMG20A siRNA Mammary_gland MDA-MB-231 0.5 -1 0.7194612309 0.8389054 DataSet_03_442
CTTNBP2 PURA siRNA Cervix HeLa 3 1.58496 1.156340e-01 0.312610404 DataSet_03_444
CTTNBP2 RELB CRISPR Colon SW480 6.26389 2.64706 1.769545e-06 1.128546e-03 DataSet_03_449
CTTNBP2 CBX2 siRNA Mammary_gland MCF7 1.6291 0.704075 4.924967e-01 0.6591417192 DataSet_03_451
CTTNBP2 PPARG siRNA Aortic_valve Valvular endothelial cell 0.658537 -0.602664 4.418902e-01 7.904370e-01 DataSet_03_456
CTTNBP2 HAND1 siRNA Placenta HPMVEC 0.125 -3 6.816933e-02 0.9463341 DataSet_03_459
CTTNBP2 TXNIP shRNA Cord_Blood CD34+ cells 2.64611 1.40387 - - DataSet_03_461
CTTNBP2 TXNIP shRNA Cord_blood ST3 6.72727 2.75002 2.499227e-03 0.0870715353 DataSet_03_462
CTTNBP2 PARP1 knockout Embryo_kidney HEK293a 1.59189 0.670738 7.498117e-04 3.655172e-03 DataSet_03_464
CTTNBP2 STAT3 shRNA Liver HepG2 1.58621 0.665581 6.807557e-02 0.3967514505 DataSet_03_465
CTTNBP2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.481793 -1.05352 - - DataSet_03_466
CTTNBP2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.10644 1.07481 - - DataSet_03_467
CTTNBP2 SMARCA1 shRNA Embryo_kidney HEK293T 1.57983 0.659771 - - DataSet_03_468
CTTNBP2 WHSC1 siRNA Prostate PC3 0.428571 -1.22239 8.263614e-02 0.26691268 DataSet_03_471
CTTNBP2 EZH2 siRNA Prostate LNCaP 0.481905 -1.05318 - - DataSet_03_472
CTTNBP2 CREBBP CRISPR Lymph U2932 8.6 3.10434 2.804911e-02 1.0000000 DataSet_03_474
CTTNBP2 EZH2 siRNA Prostate LNCaP 0.178571 -2.48543 1.947828e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate NONO by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CTTNBP2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines