Gene Overview
| Target Gene: | Col3a1 |
| NCBI Official Symbol: | Col3a1 |
| Entrez ID: | 12825 |
| Ensembl ID: | ENSMUSG00000026043 |
| Gene Full Name: | collagen, type III, alpha 1 |
| Strand: | + |
| Gene Locus: | 1 C1.1|1 23.67 cM |
| External Links: |
|
Col3a1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Col3a1
T(co)Fs
that Repress Col3a1
The Intensity of the Gene Regulated by T(co)Fs:
Col3a1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Col3a1 | Batf2 | knockdown | Bone_marrow | Bone marrow-derived macrophages | 0.575338 | -0.797517 | 0.000576236639322912 | 0.00498828227141141 | DataSet_11_012 |
| Col3a1 | Cbx2 | knockout | Gonads | Embryonic gonads | 2.27891 | 1.18834 | 1.80640552006748e-10 | 3.7845107971434e-08 | DataSet_11_018 |
| Col3a1 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.52993 | 0.613466 | 0.112702988334958 | 0.396736707578983 | DataSet_11_035 |
| Col3a1 | Foxp1 | knockout | Eye | Lens | 2.81194 | 1.49157 | - | - | DataSet_11_044 |
| Col3a1 | Gata1 | siRNA | Bone_marrow | Bone marrow-derived mast cells | 0.649363 | -0.622902 | - | - | DataSet_11_046 |
| Col3a1 | Gata4 | siRNA | Testis | TM4 | 0.664106 | -0.590514 | 3.97312868698709e-06 | 0.000758854580601721 | DataSet_11_050 |
| Col3a1 | Hsf4 | knockout | Eye | Lens | 0.182847 | -2.45129 | 0.0667701855074693 | 0.987999303842427 | DataSet_11_058 |
| Col3a1 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.193676 | -2.36828 | 2.05447148846384e-05 | 0.00222389065131384 | DataSet_11_066 |
| Col3a1 | Klf6 | shRNA | Liver | HCC | 1.67087 | 0.740603 | 0.206940185756491 | 0.998072688143085 | DataSet_11_067 |
| Col3a1 | Lhx8 | knockout | Ovary | Ovary | 1.84172 | 0.881055 | 0.00500626010178593 | 0.0356001667356952 | DataSet_11_070 |
| Col3a1 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.582648 | -0.779302 | 0.739061748931935 | 0.995635220774426 | DataSet_11_081 |
| Col3a1 | Nelfb | knockout | Embryo | Embryonic fibroblasts | 0.455946 | -1.13307 | 2.78012864548037e-07 | 8.35258333640361e-05 | DataSet_11_086 |
| Col3a1 | Nhlh2 | knockout | Eye | Retina | 0.27087 | -1.88433 | 0.0632955878393124 | 0.523726874680013 | DataSet_11_092 |
| Col3a1 | Nrf1 | knockdown | Liver | Liver | 3.60194 | 1.84878 | 0.00543402611897497 | 0.0365675603795737 | DataSet_11_096 |
| Col3a1 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 1.91912 | 0.940444 | 2.64103483740053e-05 | 0.003633823842187 | DataSet_11_105 |
| Col3a1 | Prox1 | knockout | Liver | Liver | 1.93854 | 0.954968 | - | - | DataSet_11_109 |
| Col3a1 | Rest | knockout | Brain | Brain | 8.57018 | 3.09932 | 0.150504083664114 | 1 | DataSet_11_113 |
| Col3a1 | Runx1 | knockout | Lymph | ProB cells | 1.65424 | 0.726168 | 0.149002809288027 | 0.446355737870027 | DataSet_11_116 |
| Col3a1 | Sall4 | shRNA | Embryo | ES cells | 1.53604 | 0.61922 | 0.516108350941091 | 0.999840995136314 | DataSet_11_123 |
| Col3a1 | Smad4 | siRNA | Brain | bEnd3 | 478.998 | 8.90388 | - | - | DataSet_11_127 |
| Col3a1 | Snai1 | knockout | Embryo | Embryoid body | 0.0193377 | -5.69244 | - | - | DataSet_11_129 |
| Col3a1 | Snai1 | knockout | Embryo | Teratoma | 0.466945 | -1.09868 | - | - | DataSet_11_130 |
| Col3a1 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 0.599938 | -0.737114 | 0.0966776159324934 | 0.999994003527217 | DataSet_11_132 |
| Col3a1 | Sox11 | knockout | Eye | Retina | 16.0857 | 4.00771 | - | - | DataSet_11_137 |
| Col3a1 | Sox17 | siRNA | Embryo | NG4 | 0.330424 | -1.59761 | 0.232341821314393 | 0.59780542384648 | DataSet_11_139 |
| Col3a1 | Sox9 | knockout | Lung | Trachea | 0.587196 | -0.768085 | 0.0321133773436026 | 0.226066199481771 | DataSet_11_144 |
| Col3a1 | Stat3 | knockout | Lung | Lung typeII cells | 0.328404 | -1.60646 | 0.00575979376173196 | 0.53023486969546 | DataSet_11_151 |
| Col3a1 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 4.26136 | 2.09131 | 0.00875414685261665 | 0.705058987509745 | DataSet_11_152 |
| Col3a1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.2939 | 1.1978 | 0.444032865629154 | 0.649255246106048 | DataSet_11_153 |
| Col3a1 | Tbx1 | knockout | Ear | Otic vesicles | 1.57157 | 0.652208 | 0.460452929176849 | 0.996209135879357 | DataSet_11_154 |
| Col3a1 | Tsc22d4 | shRNA | Liver | Liver | 0.530449 | -0.914713 | 0.000946910043805477 | 0.00778205883635734 | DataSet_11_169 |
| Col3a1 | Tsc22d4 | shRNA | Adipose_tissue | Abdominal fat | 1.56285 | 0.644179 | 0.0547918651713811 | 0.416743300101536 | DataSet_11_171 |
| Col3a1 | Wt1 | siRNA | Embryo_kidney | LB-22 | 0.580252 | -0.785249 | 0.000267415113404322 | 0.00840116707681471 | DataSet_11_179 |
| Col3a1 | Xbp1 | siRNA | Liver | Liver | 2.04831 | 1.03443 | 0.00751696347301013 | 0.0902560845356402 | DataSet_11_181 |
| Col3a1 | Yy1 | knockout | Muscle | Skeletal muscle | 2.57348 | 1.36372 | 0.000361636321969417 | 0.00259537785475078 | DataSet_11_182 |
| Col3a1 | Hipk2 | knockout | Heart | cardiac tissue | 0.503721 | -0.989303 | 1.598991e-03 | 6.913419e-02 | DataSet_11_238 |
| Col3a1 | Kdm5b | knockout | Heart | left ventricles | 0.565744 | -0.821779 | 0.2508675568 | 0.9999827 | DataSet_11_210 |
| Col3a1 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.185825 | -2.42798 | 1.206791e-04 | 3.530539e-03 | DataSet_11_192 |
| Col3a1 | Tet1 | knockout | Hippocampus | Hippocampus | 0.630204 | -0.666108 | 6.364869e-02 | 0.32027729 | DataSet_11_219 |
| Col3a1 | Dnmt3a | knockout | Bone_marrow | Bone marrow-derived osteoclasts | 0.504278 | -0.987707 | - | - | DataSet_11_200 |
| Col3a1 | Brca1 | knockout | Brain | mouse P7 brain | 2.59637 | 1.37649 | 3.602335e-04 | 0.10436244 | DataSet_11_201 |
| Col3a1 | Brca1 | knockout | Brain | mouse P7 cortex | 4.10181 | 2.03626 | 9.904428e-08 | 1.391968e-04 | DataSet_11_203 |
| Col3a1 | Bptf | shRNA | Mammary_gland | 4T1 cells | 0.38289 | -1.385 | 2.639363e-05 | 0.016399245 | DataSet_11_223 |
| Col3a1 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 0.608873 | -0.715787 | 1.026171e-01 | 1.0000000 | DataSet_11_208 |
| Col3a1 | Rag1 | knockout | Bone | Mice fractured callus | 1.55761 | 0.639333 | 1.737260e-04 | 2.142897e-03 | DataSet_11_230 |
| Col3a1 | Dnmt3b | siRNA | Embryo | iPSC | 0.506527 | -0.981289 | - | - | DataSet_11_242 |
| Col3a1 | Lin28a | knockout | Heart | Heart | 0.365804 | -1.45086 | 0.5086399873 | 0.8806742 | DataSet_11_243 |
| Col3a1 | Twist1 | knockout | Bone_marrow | stromal cells | 0.0147625 | -6.08192 | - | - | DataSet_11_244 |
| Col3a1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.337646 | -1.56642 | 4.733358e-03 | 0.0631333306 | DataSet_11_245 |
| Col3a1 | Fubp1 | shRNA | Brain | brain neural progenitors | 1.95035 | 0.963731 | 0.2121877467 | 1 | DataSet_11_246 |
| Col3a1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 10.5271 | 3.39603 | 6.833538e-06 | 2.858463e-04 | DataSet_11_250 |
| Col3a1 | Eed | knockout | Brain | hindbrain | 2.7932 | 1.48192 | 7.994786e-03 | 3.624978e-01 | DataSet_11_259 |
| Col3a1 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 0.123772 | -3.01424 | 4.719106e-01 | 0.71333536 | DataSet_11_267 |
| Col3a1 | Nr4a1 | knockout | Mammary_gland | PyVT mouse mammary tumor cells | 1.80486 | 0.851884 | 4.706768e-02 | 0.7273107 | DataSet_11_268 |
| Col3a1 | Dux | knockout | Embryo | Embryo | 8.46198 | 3.081 | 6.434457e-01 | 7.700653e-01 | DataSet_11_269 |
| Col3a1 | Dux | knockout | Embryo | Embryo | 8.46198 | 3.081 | 6.435024e-01 | 7.701479e-01 | DataSet_11_273 |
| Col3a1 | Lin28b | knockout | Bone_marrow | Bone marrow immature B cells | 1.80952 | 0.85561 | 4.625972e-01 | 0.9643594 | DataSet_11_274 |
| Col3a1 | Ssrp1 | CRISPR | Embryo | ES cells | 2 | 1 | 2.788867e-01 | 0.7914316 | DataSet_11_278 |
| Col3a1 | Pcgf6 | knockout | Testis | Testis | 0.569041 | -0.813395 | 4.879465e-01 | 0.9104401 | DataSet_11_282 |
| Col3a1 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 1.9972 | 0.997979 | 1.628725e-01 | 0.5395938 | DataSet_11_284 |
| Col3a1 | Setd2 | knockout | Kidney | primary renal tubular epithelial (RTE) cells | 1.67149 | 0.741133 | - | - | DataSet_11_285 |
| Col3a1 | Pdx1 | CRISPR | Liver | Liver | 0.252178 | -1.98748 | 5.505453e-02 | 0.368668394 | DataSet_11_286 |
| Col3a1 | Usp7 | siRNA | Embryo | ES cells | 2 | 1 | 6.571420e-01 | 0.7970318 | DataSet_11_287 |
| Col3a1 | Kmt2d | CRISPR | Liver | MA1L | 2.62907 | 1.39455 | 2.199057e-06 | 4.707602e-04 | DataSet_11_290 |
| Col3a1 | Kmt2d | CRISPR | Liver | MA1L | 2.68649 | 1.42572 | 1.029745e-06 | 3.872970e-04 | DataSet_11_291 |
| Col3a1 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 28.7087 | 4.84342 | 9.547742e-02 | 0.4912687513 | DataSet_11_294 |
| Col3a1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.57569 | 0.655982 | 1.964988e-01 | 7.144686e-01 | DataSet_11_297 |
| Col3a1 | Phf8 | knockout | prostate | Prostate | 2.9497 | 1.56057 | 0.3759526935 | 0.6234695 | DataSet_11_298 |
| Col3a1 | Brpf1 | shRNA | Nerve | Neural progenitor cells | 0.454843 | -1.13656 | 7.694082e-01 | 0.9999903 | DataSet_11_299 |
| Col3a1 | Arid2 | knockout | Muscle | LSK | 4 | 2 | 5.947667e-02 | 7.843001e-01 | DataSet_11_301 |
| Col3a1 | Dnmt1 | knockout | Skin | Keratinocytes | 1.58614 | 0.665517 | 4.769255e-01 | 0.7440430388 | DataSet_11_303 |
| Col3a1 | Esr1 | knockout | Liver | Liver | 1.64189 | 0.715361 | 6.430310e-02 | 1.0000000 | DataSet_11_307 |
| Col3a1 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 1.68212 | 0.750282 | 3.678723e-01 | 0.80359421 | DataSet_11_310 |
| Col3a1 | Suz12 | knockout | Lung | Alveolar macrophage | 0.420348 | -1.25034 | 5.489631e-01 | 0.8489833824 | DataSet_11_311 |
| Col3a1 | Suz12 | knockout | Lung | Alveolar macrophage | 2.25532 | 1.17333 | 8.368964e-02 | 1.534481e-01 | DataSet_11_312 |
| Col3a1 | Ahr | knockout | Liver | Liver | 0.473582 | -1.07832 | 3.722646e-03 | 0.2199707551 | DataSet_11_315 |
| Col3a1 | Satb2 | knockout | Colon | Intestine epithelium | 0.663848 | -0.591074 | 1.991604e-01 | 0.5605035983 | DataSet_11_316 |
| Col3a1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.3125 | -1.67807 | 9.243639e-03 | 0.1189248491 | DataSet_11_317 |
| Col3a1 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.297297 | -1.75002 | 7.269653e-03 | 0.3912739 | DataSet_11_318 |
| Col3a1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.213265 | -2.22928 | 2.854225e-01 | 5.052120e-01 | DataSet_11_320 |
| Col3a1 | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.630486 | -0.665463 | 4.873172e-01 | 0.8600602 | DataSet_11_321 |
| Col3a1 | Setdb1 | shRNA | Neuron | NE-4C | 3.67467 | 1.87761 | - | - | DataSet_11_323 |
| Col3a1 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 1.63066 | 0.705457 | 4.781490e-02 | 0.9609895 | DataSet_11_327 |
| Col3a1 | Ezh2 | knockout | Eye | Retina | 0.589641 | -0.76209 | 4.256770e-01 | 9.985408e-01 | DataSet_11_333 |
| Col3a1 | Ezh2 | knockout | Eye | Retina | 2.59441 | 1.3754 | 0.7436090394 | 1.0000000 | DataSet_11_334 |
| Col3a1 | Gtf2ird1 | knockout | Lip | Lip | 0.575679 | -0.796665 | 5.291582e-02 | 3.930429e-01 | DataSet_11_339 |
| Col3a1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.346741 | -1.52807 | 5.095780e-04 | 0.009358970 | DataSet_11_340 |
| Col3a1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.624464 | -0.679309 | 0.4213691815 | 0.4988732 | DataSet_11_341 |
| Col3a1 | Pcbp1 | shRNA | Thymus | Th1 | 2 | 1 | 9.966274e-03 | 0.08723011 | DataSet_11_343 |
| Col3a1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 2.04314 | 1.03079 | 1.476779e-01 | 4.038823e-01 | DataSet_11_344 |
| Col3a1 | Dux | shRNA | Embryo | ES cells | 0.423077 | -1.24101 | 1.299542e-01 | 6.205000e-01 | DataSet_11_345 |
| Col3a1 | Hoxa5 | siRNA | Heart | Adult mouse cardiomyocytes | 0.4 | -1.32193 | 2.590009e-01 | 0.57416819 | DataSet_11_302 |
Regulation Region
Expression Atlas of Col3a1