Gene Overview
| Target Gene: | Hoxc8 |
| NCBI Official Symbol: | Hoxc8 |
| Entrez ID: | 15426 |
| Ensembl ID: | ENSMUSG00000001657 |
| Gene Full Name: | homeobox C8 |
| Strand: | + |
| Gene Locus: | 15 F3|15 58.05 cM |
| External Links: |
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Hoxc8 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Hoxc8
T(co)Fs
that Repress Hoxc8
The Intensity of the Gene Regulated by T(co)Fs:
Hoxc8-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Hoxc8 | Adnp | knockout | Embryo | Whole embryonic body | 1.6104 | 0.687416 | 0.2576944667308 | 0.610836187760538 | DataSet_11_001 |
| Hoxc8 | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 1.80206 | 0.84965 | 0.0921842859851748 | 0.468981408117993 | DataSet_11_013 |
| Hoxc8 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.92 | 1.54597 | 0.320314049342422 | 0.671345361500726 | DataSet_11_014 |
| Hoxc8 | Bhlha9 | knockout | Limb | Whole limb bud | 1.561 | 0.642468 | - | - | DataSet_11_016 |
| Hoxc8 | Cbx2 | knockout | Gonads | Embryonic gonads | 2.32993 | 1.22029 | 2.05656279901438e-05 | 0.000386719574019558 | DataSet_11_018 |
| Hoxc8 | Cebpb | shRNA | Mammary_gland | 4T1 mammary tumor cells | 0.605599 | -0.723566 | 0.189019258613889 | 0.999984070881864 | DataSet_11_022 |
| Hoxc8 | Elf5 | knockout | Mammary_gland | Mammary gland | 4.84922 | 2.27775 | 0.00385249607190641 | 0.184241472964188 | DataSet_11_035 |
| Hoxc8 | Erg | knockdown | Bone_marrow | HSPCs | 2.55253 | 1.35193 | 0.832883856067755 | 0.968422028706201 | DataSet_11_038 |
| Hoxc8 | Foxp1 | knockout | Eye | Lens | 0.0802469 | -3.63941 | - | - | DataSet_11_044 |
| Hoxc8 | Gata3 | siRNA | Peripheral_blood | CD4+ T helper (Th) cells | 2.1602 | 1.11116 | 0.0450674385751543 | 0.987135756219234 | DataSet_11_048 |
| Hoxc8 | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 0.355443 | -1.49231 | - | - | DataSet_11_054 |
| Hoxc8 | Hsf4 | knockout | Eye | Lens | 0.159724 | -2.64635 | 0.168091644147222 | 0.987999303842427 | DataSet_11_058 |
| Hoxc8 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 0.439411 | -1.18636 | 0.152403881729287 | 0.415737251890893 | DataSet_11_065 |
| Hoxc8 | Lhx8 | knockout | Ovary | Ovary | 3.22996 | 1.69152 | 0.00124451115579496 | 0.0194363473055823 | DataSet_11_070 |
| Hoxc8 | Lmx1b | knockout | Kidney | Kidney | 0.660035 | -0.599386 | 0.305687546183349 | 0.631090040316059 | DataSet_11_072 |
| Hoxc8 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.129032 | -2.9542 | - | - | DataSet_11_074 |
| Hoxc8 | Neurod1 | knockout | Eye | Pineal gland | 0.319372 | -1.64669 | 0.0476728354066193 | 0.353010453112706 | DataSet_11_087 |
| Hoxc8 | Neurod1 | knockout | Eye | Retina | 4.66474 | 2.2218 | 0.594362441861187 | 0.751445448123657 | DataSet_11_088 |
| Hoxc8 | Neurod1 | knockout | Eye | Pineal gland | 2.80041 | 1.48564 | 0.411865729492055 | 0.9983937273602 | DataSet_11_089 |
| Hoxc8 | Nhlh2 | knockout | Eye | Retina | 0.409091 | -1.28951 | 0.132936500319002 | 0.523726874680013 | DataSet_11_092 |
| Hoxc8 | Otx2 | knockout | Eye | Retina | 0.421384 | -1.24679 | 0.890464481299868 | 0.999923528647439 | DataSet_11_097 |
| Hoxc8 | Pitx2 | knockout | Eye | Cornea | 1.56483 | 0.64601 | 0.117046896054936 | 0.491519664472612 | DataSet_11_103 |
| Hoxc8 | Plagl2 | knockout | Intestine | Small intestine | 1.51219 | 0.596644 | 0.280302665299699 | 0.590591991836885 | DataSet_11_104 |
| Hoxc8 | Prox1 | knockout | Liver | Liver | 29.0336 | 4.85965 | - | - | DataSet_11_109 |
| Hoxc8 | Runx1 | knockout | Embryo | Embryo | 0.622469 | -0.683926 | 0.729491922351042 | 0.999961610631375 | DataSet_11_114 |
| Hoxc8 | Sall4 | shRNA | Embryo | ES cells | 1.66165 | 0.73262 | 0.476456281960254 | 0.999840995136314 | DataSet_11_123 |
| Hoxc8 | Smad4 | siRNA | Brain | bEnd3 | 2.12368 | 1.08657 | - | - | DataSet_11_127 |
| Hoxc8 | Smad4 | knockout | Aorta | Aortic arteries | 1.89237 | 0.920197 | 0.122141419270439 | 0.508821670229594 | DataSet_11_128 |
| Hoxc8 | Snai1 | knockout | Embryo | Embryoid body | 0.0385431 | -4.69738 | - | - | DataSet_11_129 |
| Hoxc8 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 0.60668 | -0.720991 | 0.0223473472542818 | 0.174316032117735 | DataSet_11_131 |
| Hoxc8 | Sox11 | knockout | Eye | Retina | 0.454545 | -1.1375 | - | - | DataSet_11_137 |
| Hoxc8 | Sox17 | siRNA | Embryo | NG4 | 0.485258 | -1.04318 | 6.40025575969944e-05 | 0.0301303254668622 | DataSet_11_139 |
| Hoxc8 | Sp3 | knockout | Heart | Heart | 0.571894 | -0.80618 | 0.171543046323649 | 0.769319272602354 | DataSet_11_145 |
| Hoxc8 | Spdef | knockout | Colon | Colon | 0.0961306 | -3.37886 | 0.276202777953968 | 0.997507742354799 | DataSet_11_146 |
| Hoxc8 | Stat3 | knockout | Lung | Lung typeII cells | 3.64597 | 1.8663 | 0.224463264573104 | 0.785717961258929 | DataSet_11_151 |
| Hoxc8 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 5.63489 | 2.49439 | 0.195311782859592 | 0.391394052361793 | DataSet_11_153 |
| Hoxc8 | Tbx1 | knockout | Ear | Otic vesicles | 0.109432 | -3.19189 | 0.170261124487733 | 0.794884143367424 | DataSet_11_155 |
| Hoxc8 | Mapk9 | knockout | Knee | Mouse total knee | 1.83682 | 0.877214 | 1.132279e-02 | 0.144076849 | DataSet_11_237 |
| Hoxc8 | Hipk2 | knockout | Heart | cardiac tissue | 1.84566 | 0.884138 | 2.261262e-03 | 7.779540e-02 | DataSet_11_238 |
| Hoxc8 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 0.0523742 | -4.255 | 2.866204e-05 | 1.520253e-03 | DataSet_11_192 |
| Hoxc8 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.657208 | -0.605579 | - | - | DataSet_11_196 |
| Hoxc8 | Bptf | shRNA | Mammary_gland | 4T1 cells | 0.451668 | -1.14667 | 5.444304e-03 | 0.176644864 | DataSet_11_223 |
| Hoxc8 | Bcl11b | knockdown | Embryo | Embryonic fibroblasts | 0.654911 | -0.610629 | - | - | DataSet_11_226 |
| Hoxc8 | Dnmt3a | knockout | Skeletal_muscle | Satellite cells | 1.75 | 0.807355 | 2.364814e-02 | 1.0000000 | DataSet_11_208 |
| Hoxc8 | Ncl | siRNA | Embryo | ES cells | 0.571429 | -0.807355 | 5.843699e-01 | 0.7874356340 | DataSet_11_240 |
| Hoxc8 | Dnmt3a | siRNA | Embryo | iPSC | 2.37764 | 1.24953 | - | - | DataSet_11_241 |
| Hoxc8 | Twist1 | knockout | Bone_marrow | stromal cells | 3.42147e-19 | -61.342 | - | - | DataSet_11_244 |
| Hoxc8 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.399086 | -1.32523 | 3.074568e-02 | 0.2134945805 | DataSet_11_245 |
| Hoxc8 | Ezh2 | knockout | Calvaria | calvaria | 0.6 | -0.736966 | 2.281849e-01 | 0.54966233 | DataSet_11_247 |
| Hoxc8 | Kdm2a | CRISPR | Embryo | ES cells | 3 | 1.58496 | 0.1834538027 | 1.0000000 | DataSet_11_251 |
| Hoxc8 | Brca1 | siRNA | Embryo | Embryonic fibroblasts | 1.52062 | 0.604656 | 0.0949656118 | 0.4528309 | DataSet_11_256 |
| Hoxc8 | Eed | knockout | Brain | Forebrain | 104.77 | 6.71108 | 2.192522e-07 | 1.721323e-04 | DataSet_11_258 |
| Hoxc8 | Eed | knockout | Brain | midbrain | 85.8727 | 6.42413 | 1.479804e-09 | 3.748343e-06 | DataSet_11_260 |
| Hoxc8 | Dux | knockout | Embryo | Embryo | 114.521 | 6.83947 | 1.107180e-02 | 4.698972e-02 | DataSet_11_269 |
| Hoxc8 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 0.375 | -1.41504 | 3.862909e-01 | 0.6257070 | DataSet_11_271 |
| Hoxc8 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.522136 | -0.937504 | 1.052377e-01 | 0.81420760 | DataSet_11_272 |
| Hoxc8 | Dux | knockout | Embryo | Embryo | 114.521 | 6.83947 | 1.107491e-02 | 4.699831e-02 | DataSet_11_273 |
| Hoxc8 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 0.504854 | -0.986061 | 5.598486e-03 | 7.565604e-02 | DataSet_11_276 |
| Hoxc8 | Usp7 | knockout | Embryo | ES cells | 2 | 1 | 7.199797e-01 | 0.8766991 | DataSet_11_279 |
| Hoxc8 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 0.647258 | -0.627588 | 3.935783e-01 | 0.6017033 | DataSet_11_284 |
| Hoxc8 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 5 | 2.32193 | 8.626926e-02 | 0.4912687513 | DataSet_11_294 |
| Hoxc8 | Ssrp1 | CRISPR | Embryo | ES cells | 3 | 1.58496 | 5.507554e-02 | 0.28938337 | DataSet_11_296 |
| Hoxc8 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 5 | 2.32193 | 3.975733e-01 | 7.326353e-01 | DataSet_11_297 |
| Hoxc8 | Dnmt1 | knockout | Skin | Keratinocytes | 0.59574 | -0.747245 | 3.012778e-03 | 0.0632612304 | DataSet_11_303 |
| Hoxc8 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 0.454353 | -1.13811 | 2.018336e-01 | 0.80359421 | DataSet_11_310 |
| Hoxc8 | Suz12 | knockout | Lung | Alveolar macrophage | 100 | 6.64386 | 2.583963e-04 | 0.0244539570 | DataSet_11_311 |
| Hoxc8 | Satb2 | knockout | Colon | Intestine epithelium | 3.68571 | 1.88194 | 4.633381e-01 | 0.7118655549 | DataSet_11_316 |
| Hoxc8 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 3.41221 | 1.77071 | 3.685815e-02 | 3.656738e-01 | DataSet_11_319 |
| Hoxc8 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.658228 | -0.603341 | 1.902479e-01 | 4.026888e-01 | DataSet_11_320 |
| Hoxc8 | Bud31 | knockout | Testis | Spermatogonial stem cells | 1.63815 | 0.712064 | 8.784547e-01 | 0.9690539 | DataSet_11_321 |
| Hoxc8 | Ezh2 | knockout | Eye | Retina | 417.643 | 8.70613 | 0.3460749291 | 1.0000000 | DataSet_11_334 |
| Hoxc8 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 2.3242 | 1.21674 | - | - | DataSet_11_336 |
| Hoxc8 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 1.75 | 0.807355 | 4.423167e-01 | 0.79903105 | DataSet_11_338 |
| Hoxc8 | Gtf2ird1 | knockout | Lip | Lip | 0.333333 | -1.58496 | 2.849440e-01 | 6.966605e-01 | DataSet_11_339 |
| Hoxc8 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.0142247 | -6.13545 | 0.0374912182 | 0.1712697 | DataSet_11_341 |
| Hoxc8 | Hnrnpk | siRNA | Embryo | ES cells | 4.24165 | 2.08463 | 2.269645e-01 | 0.322390666 | DataSet_11_342 |
| Hoxc8 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 0.532417 | -0.909373 | 4.006846e-03 | 6.782868e-02 | DataSet_11_344 |
| Hoxc8 | Tbx20 | CRISPR | Heart | primary cardiac fibroblasts | 0.333333 | -1.58496 | 6.583009e-02 | 1.00000000 | DataSet_11_348 |
Regulation Region
Expression Atlas of Hoxc8