Gene Overview
Target Gene: PDE4D
NCBI Official Symbol: PDE4D
Entrez ID: 5144
Ensembl ID: ENSG00000113448
Gene Full Name: phosphodiesterase 4D
Strand: -
Gene Locus: 5q11.2-q12.1
External Links:

PDE4D Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PDE4D   
T(co)Fs that Repress PDE4D
The Intensity of the Gene Regulated by T(co)Fs:
PDE4D-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PDE4D ZIC2 siRNA Pancreas PANC1 1.66254 0.73339 - - DataSet_01_121
PDE4D FOXM1 siRNA Central_nervous_system U87 1.53663 0.61977 - - DataSet_01_122
PDE4D ID1 shRNA Neuroepithelium GSC8 0.59504 -0.74894 1.25274e-08 3.52061e-08 DataSet_01_134
PDE4D IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 4.96942 2.31308 4.99281e-05 0.00805 DataSet_01_137
PDE4D IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.73812 0.79753 0.16289 0.99993 DataSet_01_138
PDE4D ELK1 siRNA Peripheral_blood CD4+ T cells 0.30208 -1.72699 0.00114 0.01195 DataSet_01_162
PDE4D GATA3 siRNA Peripheral_blood CD4+ T cells 1.60977 0.68685 0.06166 0.38461 DataSet_01_163
PDE4D JUN siRNA Peripheral_blood CD4+ T cells 0.29832 -1.74509 0.00082 0.01355 DataSet_01_164
PDE4D MAF siRNA Peripheral_blood CD4+ T cells 0.25579 -1.96699 0.00031 0.01183 DataSet_01_165
PDE4D NFATC3 siRNA Peripheral_blood CD4+ T cells 0.25252 -1.98551 0.00038 0.01447 DataSet_01_166
PDE4D STAT3 siRNA Peripheral_blood CD4+ T cells 48.8218 5.60945 0.25541 0.99183 DataSet_01_168
PDE4D GATA2 siRNA Prostate LNCaP 0.26384 -1.92227 3.84623e-07 3.16589e-05 DataSet_01_193
PDE4D TP63 siRNA Head_and_neck SCC-1 0.65829 -0.60322 - - DataSet_01_198
PDE4D TP63 siRNA Head_and_neck SCC-1 0.09516 -3.39346 - - DataSet_01_199
PDE4D XBP1 shRNA Mammary_gland MDA-MB-231 0.59763 -0.74268 0.00041 0.01084 DataSet_01_204
PDE4D FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.38498 -1.37715 - - DataSet_01_210
PDE4D LIN28A siRNA Embryo H9 0.61365 -0.70452 0.03411 0.1074 DataSet_01_215
PDE4D HIF1A shRNA Liver HuH7 0.58838 -0.76518 - - DataSet_01_224
PDE4D STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.98543 0.98945 0.00049 0.00435 DataSet_01_239
PDE4D YBX1 shRNA Mammary_gland MDA 0.65421 -0.61217 4.72257e-07 8.49478e-06 DataSet_01_259
PDE4D SOX4 shRNA Mammary_gland MDA-MB-231 0.37883 -1.40038 0.00629 0.09594 DataSet_01_260
PDE4D HES1 shRNA Haematopoietic_and_lymphoid_tissue_Blood CUTLL1 0.59588 -0.7469 6.23484e-06 0.00035 DataSet_01_266
PDE4D FOXO3 siRNA Pancreas PANC1 0.34054 -1.5541 - - DataSet_01_267
PDE4D ESRRA shRNA Embryo_kidney 293T 2.08143 1.05757 0.00992 0.56407 DataSet_01_280
PDE4D TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 4.30837 2.10714 9.34888e-10 7.60923e-08 DataSet_01_286
PDE4D TFAP4 siRNA Brain BE(2)-C 0.36498 -1.45412 0.62327 0.63281 DataSet_01_295
PDE4D MYCN siRNA Brain BE(2)-C 1.79669 0.84535 0.71187 1 DataSet_01_296
PDE4D PTEN shRNA Skin A431 1.81016 0.85612 0.03013 0.14405 DataSet_01_301
PDE4D ELK3 shRNA Mammary_gland MDA-MB-231 0.62838 -0.67028 0.00011 0.00065 DataSet_01_318
PDE4D REST siRNA Skin NHEK 1.58848 0.66765 0.00572 0.0758 DataSet_01_337
PDE4D CDX2 siRNA Colon COLO320 0.57322 -0.80283 - - DataSet_01_357
PDE4D PAX3 shRNA Soft_tissue Rh30 1.71938 0.78189 - - DataSet_01_359
PDE4D FIP1L1 shRNA Liver HepG2 0.53051 -0.91455 0.00084 0.01387 DataSet_02_103
PDE4D U2AF2 shRNA Liver HepG2 1.98356 0.98809 0.43741 0.58222 DataSet_02_105
PDE4D SSB shRNA Liver HepG2 0.62755 -0.6722 0.00675 0.0208 DataSet_02_107
PDE4D ZNF622 shRNA Liver HepG2 0.63994 -0.64399 0.00457 0.01747 DataSet_02_108
PDE4D GTF2F1 shRNA Liver HepG2 2.05205 1.03707 0.00244 0.20753 DataSet_02_110
PDE4D XRCC5 shRNA Liver HepG2 2.36712 1.24313 0.00085 0.12055 DataSet_02_114
PDE4D SUB1 shRNA Liver HepG2 1.65753 0.72904 0.01775 0.15165 DataSet_02_117
PDE4D EWSR1 shRNA Liver HepG2 0.51286 -0.96337 6e-04 0.04098 DataSet_02_122
PDE4D PCBP2 shRNA Liver HepG2 1.51233 0.59677 0.00908 0.07442 DataSet_02_123
PDE4D HNRNPLL shRNA Liver HepG2 0.51402 -0.96011 0.0088 0.03124 DataSet_02_125
PDE4D SNRNP70 shRNA Liver HepG2 1.50334 0.58817 0.03807 0.10282 DataSet_02_126
PDE4D PRPF4 shRNA Liver HepG2 0.49408 -1.01718 7e-04 0.02524 DataSet_02_128
PDE4D TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.05797 -4.10852 0.1147 0.39161 DataSet_02_129
PDE4D POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.19672 -2.34577 0.03155 0.70011 DataSet_02_130
PDE4D PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.27536 -1.8606 0.15526 0.2494 DataSet_02_131
PDE4D AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.34375 -1.54057 0.00628 0.10192 DataSet_02_132
PDE4D SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.05797 -4.10852 0.00279 0.22541 DataSet_02_133
PDE4D SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 0.07246 -3.7866 0.02224 0.11581 DataSet_02_134
PDE4D PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.30435 -1.71621 0.17613 0.32761 DataSet_02_135
PDE4D HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 0.10145 -3.30117 0.04238 0.20896 DataSet_02_136
PDE4D PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.10145 -3.30117 0.0074 0.1955 DataSet_02_137
PDE4D RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.32633 0.5969 DataSet_02_138
PDE4D RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.07143 -3.80735 0.00115 0.44546 DataSet_02_139
PDE4D RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 0.15942 -2.64909 0.03103 0.22495 DataSet_02_141
PDE4D RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.00205 0.02173 DataSet_02_143
PDE4D DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.07563 0.51061 DataSet_02_145
PDE4D CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.24458 0.65101 DataSet_02_146
PDE4D FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.05848 0.16605 DataSet_02_147
PDE4D ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 2.85714 1.51457 0.34984 0.6212 DataSet_02_148
PDE4D NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.28562 0.48685 DataSet_02_149
PDE4D SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.04418 0.46775 DataSet_02_150
PDE4D RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.1 -3.32193 0.01728 0.23644 DataSet_02_151
PDE4D FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.36364 -1.45943 0.87301 0.93719 DataSet_02_155
PDE4D HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.00121 0.51515 DataSet_02_156
PDE4D PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.03704 -4.75489 0.13326 0.24953 DataSet_02_158
PDE4D XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57143 -0.80735 0.34821 0.8157 DataSet_02_159
PDE4D AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.18182 1.12553 0.34587 0.75869 DataSet_02_162
PDE4D U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44444 -1.16993 0.62891 0.76003 DataSet_02_165
PDE4D EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.09677 -3.36923 0.12102 0.33858 DataSet_02_167
PDE4D RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 0.4058 -1.30117 0.08548 0.18665 DataSet_02_168
PDE4D U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.08372 0.18489 DataSet_02_170
PDE4D RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.27901 0.48498 DataSet_02_171
PDE4D ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 2.95238 1.56188 0.16252 1 DataSet_02_177
PDE4D TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.8 2.26303 0.04413 1 DataSet_02_178
PDE4D STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 3.72 1.8953 0.08756 1 DataSet_02_182
PDE4D RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.73333 0.79355 0.4966 1 DataSet_02_190
PDE4D LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.75 1.90689 0.38481 1 DataSet_02_195
PDE4D UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.06664 1 DataSet_02_198
PDE4D TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.05354 1 DataSet_02_201
PDE4D ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.79208 1 DataSet_02_203
PDE4D E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 1.55 0.63227 0.30694 1 DataSet_02_205
PDE4D GATA3 siRNA Mammary_gland MCF7 1.58024 0.660141 0.203735028818479 0.352158803985824 DataSet_03_103
PDE4D GATA6 siRNA Stomach AGS 3.19075 1.6739 0.000991645439240139 0.120663313570969 DataSet_03_108
PDE4D MEF2D shRNA Liver HuH7 1.8091 0.855271 - - DataSet_03_162
PDE4D MITF siRNA Skin MZ7 1.66086 0.731932 4.17633005485406e-05 0.000418163333111419 DataSet_03_165
PDE4D MITF siRNA Skin Ma-Mel-15 1.51443 0.59877 0.0265318722854395 0.237370266209119 DataSet_03_167
PDE4D MTA2 siRNA Stomach SGC-7901 0.349393 -1.51708 - - DataSet_03_169
PDE4D MYB siRNA Cord_Blood CD34+ progenitor cells 1.60212 0.679983 - - DataSet_03_170
PDE4D PHB shRNA Embryo Embryonic stem cells (ESCs) 2.03373 1.02413 0.000157635570931268 0.00167087532477563 DataSet_03_211
PDE4D RELB siRNA Immortalized_keratinocyte HaCaT 0.272091 -1.87784 2.74884995029676e-05 0.000430582643640419 DataSet_03_227
PDE4D SOX11 siRNA Lung_fibroblast NHLF 1.80912 0.855286 0.107267137731925 0.498819265682601 DataSet_03_237
PDE4D SOX11 siRNA Lung_fibroblast NHLF 2.25821 1.17518 0.0198525629547475 0.236395459197986 DataSet_03_238
PDE4D SOX2 siRNA Lung LK2 1.90428 0.929247 - - DataSet_03_241
PDE4D SOX2 siRNA Embryo NTera-2 1.69406 0.760483 0.000139323541005781 0.0085133631447653 DataSet_03_243
PDE4D STAT3 CRISPR Embryo hESC 3.01419 1.59177 0.000596569441720005 0.0185927960389355 DataSet_03_258
PDE4D STAT3 siRNA Prostate DU145 0.66085 -0.597605 0.00018530416476999 0.012511583459823 DataSet_03_260
PDE4D TET1 siRNA Embryo NCCIT 0.649184 -0.6233 0.000963048530441334 0.0103847118768996 DataSet_03_269
PDE4D TET2 siRNA Embryo NCCIT 0.586544 -0.76969 0.000197493885449002 0.00339890451836853 DataSet_03_270
PDE4D TET3 siRNA Embryo NCCIT 0.606389 -0.721685 0.000410218926979784 0.00876349452898059 DataSet_03_273
PDE4D TP53 knockout Haematopoietic_and_lymphoid_tissue MOLP8 1.5257 0.609469 0.173916056281339 0.805286665936779 DataSet_03_280
PDE4D CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.0505061553566437 0.109009650736574 DataSet_04_004
PDE4D CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 6.5 2.70044 0.506522937873343 0.757249587930317 DataSet_04_005
PDE4D DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.1 -3.32193 0.00676684979238163 0.518744806039141 DataSet_04_006
PDE4D E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.75 0.807355 0.0151792723640793 0.460888933881103 DataSet_04_007
PDE4D ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.0399927796987747 0.66157425514643 DataSet_04_009
PDE4D FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 6.88889 2.78427 0.362163814943967 0.488070339846643 DataSet_04_010
PDE4D FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.266667 -1.90689 0.0262119048397101 0.747473862097999 DataSet_04_011
PDE4D MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.275644406375157 0.353200320488098 DataSet_04_012
PDE4D NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 218.958 7.77451 1.31818676841311e-05 0.0015885371102682 DataSet_04_014
PDE4D SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.147371035424784 0.285173492008726 DataSet_04_018
PDE4D SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.273613047614637 0.61151439250043 DataSet_04_020
PDE4D XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.767718397825073 0.877445905575531 DataSet_04_021
PDE4D YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.571429 -0.807355 0.768851318544982 0.905124355734017 DataSet_04_022
PDE4D APTX CRISPR Liver HepG2 3.75 1.90689 0.0429552123920468 0.455813913069024 DataSet_04_025
PDE4D ACTN4 CRISPR Liver HepG2 0.453137 -1.14198 0.00117077468221308 0.0314049003592783 DataSet_04_042
PDE4D CNOT7 shRNA Liver HepG2 2.93997 1.5558 0.000364337176530239 0.00428434671353929 DataSet_04_051
PDE4D UBE2L3 shRNA Liver HepG2 2.89538 1.53376 4.41885797666338e-05 0.00489832006442962 DataSet_04_055
PDE4D ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.15 -2.73697 0.178203739791031 0.368652029562024 DataSet_04_048
PDE4D DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.641409838549929 0.938181423208644 DataSet_04_047
PDE4D DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.0942369917078942 0.467629358554314 DataSet_04_050
PDE4D NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.62069 -0.688056 0.632948802273288 0.791742841329576 DataSet_04_046
PDE4D RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0147059 -6.08746 0.147131819913499 0.677827118044092 DataSet_04_076
PDE4D SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.08 -3.64386 0.302752385700329 1 DataSet_04_077
PDE4D SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.12 -3.05889 0.321018315872944 0.694994966941846 DataSet_04_073
PDE4D SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.4 -1.32193 0.481928031441829 0.649200127624152 DataSet_04_049
PDE4D CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.75 1.90689 0.0490491928140737 0.219645534834082 DataSet_02_38
PDE4D HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.60714 0.684498 0.48016365521627 0.798146535255441 DataSet_02_75
PDE4D HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.41667 2.14296 0.150990565167832 0.643385843739619 DataSet_02_45
PDE4D LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.83333 1.5025 0.288531727173214 0.462655859903671 DataSet_02_35
PDE4D NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.20833 2.07325 0.220923212883883 0.499084579744206 DataSet_02_32
PDE4D SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.25 -2 0.421452376118925 0.58216611458684 DataSet_02_47
PDE4D SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.441176 -1.18057 0.495454603501213 0.835639466797749 DataSet_02_49
PDE4D TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.91667 0.938599 0.537206512149758 0.712262298664942 DataSet_02_43
PDE4D TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.25 1.16992 0.322543385969981 0.477810363147952 DataSet_02_33
PDE4D ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.619681411418463 0.754828509239158 DataSet_04_060
PDE4D DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.142857 -2.80735 0.53049364424731 0.850821834877491 DataSet_04_063
PDE4D PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 1.71429 0.777608 0.714772876592299 0.918728232984676 DataSet_04_065
PDE4D UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.275862 -1.85798 0.229143870416206 0.47886511162557 DataSet_04_062
PDE4D EZH2 siRNA Uterus Hec-1A 0.650671 -0.62 6.339064e-05 4.662635e-03 DataSet_03_314
PDE4D EZH2 shRNA Colon SW480 1.6097 0.68679 - - DataSet_03_298
PDE4D NSD2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.63837 0.712265 1.804369e-04 5.132456e-03 DataSet_03_303
PDE4D ELF3 CRISPR Bile_duct HBDEC2 1.63096 0.70572 1.187415e-04 1.359226e-03 DataSet_03_304
PDE4D SNAI2 shRNA Pancreas KLM1 0.286708 -1.80235 3.949307e-03 0.13032044 DataSet_03_307
PDE4D PRMT1 shRNA Lung A549 0.587901 -0.766355 - - DataSet_03_342
PDE4D ARID3B CRISPR Colon HCT15 0.492099 -1.02298 - - DataSet_03_335
PDE4D TET1 CRISPR Mammary_gland MDA-MB-231 1.55996 0.641512 3.939164e-04 6.924480e-03 DataSet_03_347
PDE4D SKI CRISPR Blood HL60 1.65294 0.725031 5.784827e-02 0.389745412 DataSet_03_351
PDE4D ETV5 knockdown Colon HT29 1.73411 0.794197 1.813315e-02 0.155555692 DataSet_03_353
PDE4D PARP1 siRNA Prostate LNCaP 3.20136 1.67869 7.702441e-02 0.321731183 DataSet_03_354
PDE4D CREBBP CRISPR Brain U5-NPC 3.5967 1.84667 0.0421830878 0.7490853 DataSet_03_356
PDE4D PTPN14 CRISPR Brain U5-NPC 1.7469 0.8048 1.209990e-01 0.34774800 DataSet_03_357
PDE4D TP53 CRISPR Brain U5-NPC 3.11557 1.63949 3.712515e-02 1.712468e-01 DataSet_03_358
PDE4D ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 3.06502 1.6159 1.308497e-05 1.406846e-04 DataSet_03_362
PDE4D MYC siRNA Peripheral_blood T lymphocyte 1.79888 0.847099 4.782563e-04 0.014778272 DataSet_03_363
PDE4D EP300 shRNA Mammary_gland MCF10AT 2.24958 1.16966 9.535570e-03 0.072278794 DataSet_03_364
PDE4D TP53 knockout Stomach SNU1 1.89995 0.925962 0.1664298765 0.9301241 DataSet_03_365
PDE4D DNMT3A knockout Embryo_kidney HEK293T 55.9037 5.80487 - - DataSet_03_369
PDE4D TPR shRNA Bone_marrow U2OS 1.64103 0.714604 1.635503e-02 1.862901e-01 DataSet_03_370
PDE4D ZFP36L1 siRNA Urinary_bladder J82 2.65789 1.41028 - - DataSet_03_371
PDE4D E2F1 siRNA Nasopharynx HK1 0.571763 -0.806511 4.687747e-01 1.000000e+00 DataSet_03_373
PDE4D HNRNPU siRNA Colon RKO 0.590446 -0.760122 - - DataSet_03_374
PDE4D GLI1 siRNA Skeletal_muscle RMS13 2.80743 1.48925 2.524153e-03 0.034623630 DataSet_03_375
PDE4D ZNF213 siRNA Mammary_gland MCF7 0.509688 -0.972313 9.644286e-02 5.078795e-01 DataSet_03_376
PDE4D EZH2 CRISPR Ovary SKOV3 4.33632 2.11647 3.006776e-04 0.0105049243 DataSet_03_378
PDE4D DDX5 shRNA Stomach HGC-27 1.59933 0.677465 - - DataSet_03_379
PDE4D NFKB2 siRNA Bone_marrow U2OS 2.62069 1.38995 6.138565e-03 0.11106960 DataSet_03_381
PDE4D NFKBIA shRNA Bone_marrow U2OS 0.0571195 -4.12987 6.015046e-01 0.87005461 DataSet_03_389
PDE4D BMI1 shRNA Bile_duct QBC-939 2.20501 1.14078 7.122335e-04 0.0060724839 DataSet_03_395
PDE4D RELA CRISPR Brain T30 1.59244 0.671242 0.3939355177 0.8400824 DataSet_03_399
PDE4D TFAP2A knockout Embryo H9 0.413452 -1.27421 4.808431e-04 0.02177958 DataSet_03_405
PDE4D SIRT1 siRNA Pancreas PANC1 2.76923 1.46949 4.913366e-02 0.135138235 DataSet_03_410
PDE4D USP22 shRNA Liver HuH7 6.82948 2.77178 - - DataSet_03_411
PDE4D ZKSCAN3 CRISPR Colon HCT116 0.205418 -2.28337 1.058375e-02 0.239980459 DataSet_03_415
PDE4D FOXK2 shRNA Ovary OVCAR-5 1.53804 0.621096 3.384429e-01 0.45666609 DataSet_03_419
PDE4D FOXP3 CRISPR Peripheral_blood Naive Treg 1.5096 0.594169 2.707210e-01 0.629711110 DataSet_03_427
PDE4D USP7 shRNA Skin xenograft cells 0.407818 -1.294 0.26488376 0.4348960 DataSet_03_431
PDE4D POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.384468 -1.37907 1.907785e-01 0.549450744 DataSet_03_434
PDE4D POU2AF1 CRISPR Lymph SUDHL4 0.218491 -2.19436 1.565139e-03 0.014828824 DataSet_03_435
PDE4D EP300 knockout Pancreas HPAF-II orthotopic cells 0.521472 -0.939338 1.315505e-05 4.447950e-04 DataSet_03_436
PDE4D CIC knockout Brain Immortalized Astrocyte Cells 6.17965 2.62753 1.336435e-06 1.741642e-03 DataSet_03_438
PDE4D SETDB1 shRNA Colon HCT116 0.0565093 -4.14537 - - DataSet_03_440
PDE4D DAXX shRNA Mammary_gland MDA-MB-231 0.638569 -0.647085 6.249350e-02 0.27718892 DataSet_03_441
PDE4D PHF14 siRNA Mammary_gland MDA-MB-231 1.55873 0.640373 0.0994044302 0.5159506 DataSet_03_443
PDE4D RELB CRISPR Colon SW480 1.50776 0.592411 9.979168e-03 7.837568e-02 DataSet_03_449
PDE4D CBX2 siRNA Mammary_gland MDA-MB-231 0.291818 -1.77686 2.054731e-05 6.729082e-04 DataSet_03_450
PDE4D SMARCA2 shRNA Lung HCC2302 0.666522 -0.585276 2.616174e-06 6.311207e-06 DataSet_03_455
PDE4D TXNIP shRNA Cord_Blood CD34+ cells 2.29846 1.20067 - - DataSet_03_461
PDE4D TXNIP shRNA Cord_blood ST3 3.1171 1.64021 1.744480e-03 0.0732400212 DataSet_03_462
PDE4D PARP1 knockout Embryo_kidney HEK293a 2.38225 1.25233 1.925733e-09 8.261596e-08 DataSet_03_464
PDE4D SMARCA1 Cas13 Embryo_kidney HEK293T 0.616646 -0.697486 - - DataSet_03_466
PDE4D SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.70492 0.769702 - - DataSet_03_467
PDE4D CREBBP CRISPR Lymph U2932 1.65138 0.723669 8.875530e-01 1.0000000 DataSet_03_474
PDE4D EZH2 siRNA Prostate LNCaP 0.583333 -0.777608 2.068053e-01 1.0000000 DataSet_03_475
PDE4D CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4.44444 2.152 0.3724503 0.534146627 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate POLR2G by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PDE4D
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines