Gene Overview
Target Gene: PGLYRP4
NCBI Official Symbol: PGLYRP4
Entrez ID: 57115
Ensembl ID: ENSG00000163218
Gene Full Name: peptidoglycan recognition protein 4
Strand: -
Gene Locus: 1q21.3
External Links:

PGLYRP4 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PGLYRP4   
T(co)Fs that Repress PGLYRP4
The Intensity of the Gene Regulated by T(co)Fs:
PGLYRP4-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PGLYRP4 TCF3 shRNA Mammary_gland MDA-MB468 0.40975 -1.28718 8.93978e-06 0.00046 DataSet_01_116
PGLYRP4 ZIC2 siRNA Pancreas PANC1 1.68617 0.75375 - - DataSet_01_121
PGLYRP4 FOXM1 siRNA Central_nervous_system U87 1.76227 0.81744 - - DataSet_01_122
PGLYRP4 POLR3A siRNA Mammary_gland MCF7 3.04517 1.60652 - - DataSet_01_139
PGLYRP4 EHF siRNA Corneal_epithelial Corneal epithelial cells 0.64228 -0.63873 0.00017 0.00644 DataSet_01_147
PGLYRP4 HOXB7 siRNA Pancreas Capan-1 0.52545 -0.92837 0.07178 0.56934 DataSet_01_170
PGLYRP4 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.6167 -0.69737 0.11693 0.28231 DataSet_01_185
PGLYRP4 GATA2 siRNA Prostate LNCaP 1.58676 0.66608 0.03201 0.08455 DataSet_01_193
PGLYRP4 CREB1 shRNA Parotid_gland H3118 MEC 1.70948 0.77356 0.60167 0.84217 DataSet_01_194
PGLYRP4 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 2.0227 1.01628 - - DataSet_01_209
PGLYRP4 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.37284 -1.42336 - - DataSet_01_210
PGLYRP4 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 0.59055 -0.75987 0.00499 0.03405 DataSet_01_217
PGLYRP4 SNAI2 shRNA Skin Primary human keratinocytes 13.9906 3.80638 7.85222e-06 0.00444 DataSet_01_225
PGLYRP4 ESRRA shRNA Embryo_kidney 293T 0.65828 -0.60322 0.27756 0.79499 DataSet_01_280
PGLYRP4 POSTN shRNA Brain GSC272 3.13874 1.65019 0.02811 0.51529 DataSet_01_293
PGLYRP4 TFAP4 siRNA Brain BE(2)-C 0.20286 -2.30142 0.33187 0.51625 DataSet_01_295
PGLYRP4 SOX17 siRNA Umbilical_vein HUVEC 1.60688 0.68426 0.29236 0.99998 DataSet_01_300
PGLYRP4 PTEN shRNA Skin A431 3.71107 1.89183 0.04132 0.16604 DataSet_01_301
PGLYRP4 PTEN shRNA Mammary_gland SKBR3 0.48631 -1.04006 0.1197 0.62975 DataSet_01_303
PGLYRP4 SOX9 siRNA Prostate VCaP 0.46472 -1.10557 0.10326 0.9316 DataSet_01_308
PGLYRP4 SOX9 siRNA Prostate VCaP 0.46472 -1.10557 0.10326 0.9316 DataSet_01_309
PGLYRP4 TFAP2C siRNA Lung NCI-H292 0.66477 -0.58908 - - DataSet_01_312
PGLYRP4 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.53482 -0.90287 0.1402 0.37058 DataSet_01_313
PGLYRP4 GRHL3 siRNA Skin NHEK 0.53609 -0.89946 0.01107 0.3166 DataSet_01_336
PGLYRP4 HIF1A siRNA Oral_cavity OEC-M1 0.51659 -0.95291 0.03662 0.85151 DataSet_01_348
PGLYRP4 CDX2 siRNA Colon COLO320 4.02717 2.00977 - - DataSet_01_357
PGLYRP4 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 1 1 DataSet_02_130
PGLYRP4 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64706 -0.62803 0.56915 0.70783 DataSet_02_132
PGLYRP4 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 1.58333 0.66297 0.26643 0.40835 DataSet_02_134
PGLYRP4 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 2.14286 1.09954 0.52189 0.74186 DataSet_02_138
PGLYRP4 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.625 1.39232 0.01245 0.44546 DataSet_02_139
PGLYRP4 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47059 -1.08746 0.60491 0.7791 DataSet_02_140
PGLYRP4 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 22.3333 4.48113 0.00554 0.09655 DataSet_02_142
PGLYRP4 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.18999 0.26777 DataSet_02_143
PGLYRP4 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 5.35294 2.42033 0.03421 0.22383 DataSet_02_144
PGLYRP4 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 5.33333 2.41504 0.20281 0.6226 DataSet_02_146
PGLYRP4 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.875 0.90689 0.21726 0.50754 DataSet_02_148
PGLYRP4 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 2.23529 1.16046 0.07489 0.2607 DataSet_02_149
PGLYRP4 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.08697 0.51688 DataSet_02_150
PGLYRP4 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 9 3.16993 0.00301 0.23369 DataSet_02_152
PGLYRP4 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 3.6875 1.88264 0.00448 0.41577 DataSet_02_153
PGLYRP4 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.04057 0.38026 DataSet_02_154
PGLYRP4 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.57692 -0.79355 0.38739 0.60393 DataSet_02_155
PGLYRP4 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.06095 0.88657 DataSet_02_157
PGLYRP4 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.54545 0.62803 0.33615 0.46943 DataSet_02_158
PGLYRP4 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.62631 0.90842 DataSet_02_159
PGLYRP4 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 5.25 2.39232 0.00778 0.66851 DataSet_02_161
PGLYRP4 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46154 -1.11548 0.22032 0.68066 DataSet_02_162
PGLYRP4 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.27127 0.50395 DataSet_02_163
PGLYRP4 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47059 -1.08746 0.89178 0.94601 DataSet_02_166
PGLYRP4 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6 0.67807 0.57819 0.75449 DataSet_02_167
PGLYRP4 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.02357 0.09702 DataSet_02_168
PGLYRP4 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.25398 0.35836 DataSet_02_169
PGLYRP4 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.82353 1.4975 0.08233 0.18278 DataSet_02_170
PGLYRP4 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58824 -0.76553 0.66967 0.80398 DataSet_02_171
PGLYRP4 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.65909 -0.60145 0.56374 1 DataSet_02_178
PGLYRP4 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.61345 -0.70499 0.69587 1 DataSet_02_181
PGLYRP4 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 2.45902 1.29808 0.09345 1 DataSet_02_182
PGLYRP4 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 2.03704 1.02647 0.36813 1 DataSet_02_184
PGLYRP4 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.51327 -0.9622 0.69102 1 DataSet_02_187
PGLYRP4 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 4.30081 2.10461 0.37641 1 DataSet_02_190
PGLYRP4 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.78049 0.83227 0.23755 1 DataSet_02_201
PGLYRP4 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.31818 -1.65208 0.1504 1 DataSet_02_203
PGLYRP4 ZFX siRNA Mammary_gland MCF7 1.9375 0.9542 0.06312 0.23002 DataSet_02_206
PGLYRP4 ASCL1 siRNA Lung DMS79 0.60804 -0.717761 0.23778959248583 0.854007056101987 DataSet_03_016
PGLYRP4 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.637911 -0.648574 0.137541518958226 0.781242674895867 DataSet_03_025
PGLYRP4 BCL6 siRNA Lymph Pfeiffer DLBCL 1.53428 0.61756 0.0912930708196277 0.561129097562881 DataSet_03_026
PGLYRP4 GRHL3 siRNA Skin Primary neonatal keratinocytes 0.496551 -1.00999 0.00861539385397348 0.202011050859718 DataSet_03_113
PGLYRP4 HIC1 CRISPR Prostate PC3 0.347929 -1.52313 - - DataSet_03_118
PGLYRP4 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.02191 1.01572 0.110961593157659 0.973283724837266 DataSet_03_134
PGLYRP4 Klf4 siRNA Skin Primary neonatal keratinocytes 0.552946 -0.854789 0.115760532273567 0.256843680981977 DataSet_03_147
PGLYRP4 KLF5 siRNA Stomach KatoIII 1.51869 0.602831 0.140847622972425 0.59012105473953 DataSet_03_150
PGLYRP4 MEF2D shRNA Liver HuH7 1.60146 0.67939 - - DataSet_03_162
PGLYRP4 MITF siRNA Skin SK-MEL-5 0.629683 -0.667303 0.00439657462296085 0.0109643753987747 DataSet_03_168
PGLYRP4 MTA2 siRNA Stomach SGC-7901 1.91254 0.935493 - - DataSet_03_169
PGLYRP4 MYB siRNA Cord_Blood CD34+ progenitor cells 5.62557 2.492 - - DataSet_03_170
PGLYRP4 MYC siRNA Colon HT29 2.31962 1.21389 - - DataSet_03_177
PGLYRP4 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 2.8913 1.53172 - - DataSet_03_246
PGLYRP4 STAT6 siRNA Umbilical_vein HUVEC 0.267223 -1.90388 0.0568072242868407 0.740977923278918 DataSet_03_264
PGLYRP4 TP63 siRNA Skin Primary neonatal keratinocytes 0.389433 -1.36055 0.00300950390654561 0.0213460025913367 DataSet_03_281
PGLYRP4 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.642857 -0.63743 0.0684510989393124 0.588057568548328 DataSet_04_001
PGLYRP4 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.88889 0.917538 0.200839259459953 0.593363115840371 DataSet_04_006
PGLYRP4 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 7.41667 2.89077 0.00569406958336761 0.0609075923875511 DataSet_04_010
PGLYRP4 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.9 0.925999 0.123137249544381 0.794501855965956 DataSet_04_013
PGLYRP4 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 34.583 5.11199 0.829872263562929 0.88899712207827 DataSet_04_014
PGLYRP4 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.11667 1.08179 0.0697968584933837 0.453478596196344 DataSet_04_017
PGLYRP4 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.65 0.722466 0.10811107394772 0.263181476893363 DataSet_04_019
PGLYRP4 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.62963 -0.667425 0.0671922136273745 0.285735057710524 DataSet_04_021
PGLYRP4 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.377358 -1.40599 0.545615227554015 0.680170123694404 DataSet_04_023
PGLYRP4 ANXA2 CRISPR Liver HepG2 3.15 1.65535 0.0232603314014059 0.605768083801457 DataSet_04_024
PGLYRP4 APTX CRISPR Liver HepG2 0.661972 -0.595158 0.453579275857849 0.76774469276947 DataSet_04_025
PGLYRP4 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.53125 0.61471 0.0465330150620037 0.163985270975458 DataSet_04_048
PGLYRP4 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.560976 -0.83399 0.196190942635432 0.709930091110656 DataSet_04_047
PGLYRP4 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.3 1.20163 0.113382183550331 0.265664299527736 DataSet_04_046
PGLYRP4 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.323171 -1.62963 0.00124553883543786 0.0166835227879465 DataSet_02_34
PGLYRP4 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.39344 1.25909 0.00918214573475225 0.393478982766751 DataSet_02_75
PGLYRP4 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.545732 -0.873736 0.0540232742292344 0.507768498242424 DataSet_02_45
PGLYRP4 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.652439 -0.616085 0.0178169168903982 0.0570448557380277 DataSet_02_47
PGLYRP4 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.010091888871553 0.396811658374965 DataSet_02_49
PGLYRP4 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.304878 -1.7137 0.00052843574877108 0.0193185602312486 DataSet_02_43
PGLYRP4 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.240854 -2.05377 0.00053871068808556 0.00854472974894901 DataSet_02_33
PGLYRP4 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 18.75 4.22882 0.000470230742291882 0.0172508180805643 DataSet_04_060
PGLYRP4 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.875 0.906891 0.483963759934152 0.662383009539484 DataSet_04_064
PGLYRP4 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 52.1667 5.70506 0.000358932347176199 0.0370497129649969 DataSet_04_061
PGLYRP4 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.0625 1.04439 0.470047726503971 0.823186305195367 DataSet_04_063
PGLYRP4 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 5.75 2.52356 0.21938314118023 0.592732259053957 DataSet_04_065
PGLYRP4 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 9.33333 3.22239 0.0593555595071496 0.229698637055968 DataSet_04_062
PGLYRP4 ELF3 CRISPR Bile_duct HBDEC2 1.56535 0.646488 2.918815e-01 3.817233e-01 DataSet_03_304
PGLYRP4 SNAI2 shRNA Pancreas KLM1 0.117348 -3.09114 1.188241e-01 0.44897866 DataSet_03_307
PGLYRP4 AEBP1 siRNA Central_nervous_system U87MG 1.67689 0.745787 5.937260e-03 0.9347200 DataSet_03_338
PGLYRP4 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 26.2079 4.71193 7.618553e-04 2.772727e-03 DataSet_03_362
PGLYRP4 ZNF213 siRNA Mammary_gland MCF7 0.171279 -2.54558 4.851517e-01 7.172311e-01 DataSet_03_376
PGLYRP4 TRIM8 siRNA Mammary_gland MCF7 2.69231 1.42884 4.509444e-03 0.0312867254 DataSet_03_388
PGLYRP4 ILF2 siRNA Stomach SGC-7901 0.1 -3.32193 0.1451458049 0.31662166 DataSet_03_393
PGLYRP4 IKZF2 CRISPR Lymph CAR T Cell 2.24728 1.16818 1.364573e-01 0.601605393 DataSet_03_397
PGLYRP4 TLE4 CRISPR Lymph CAR T Cell 4.01412 2.00508 1.254316e-01 0.40678138 DataSet_03_398
PGLYRP4 EHF shRNA Stomach MKN7 0.188858 -2.40462 - - DataSet_03_402
PGLYRP4 BRD4 CRISPR Lymph CD8+ T cells 0.333333 -1.58496 - - DataSet_03_420
PGLYRP4 PRDM1 CRISPR Lymph CD8+ T cells 0.5 -1 - - DataSet_03_421
PGLYRP4 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.380952 -1.39232 - - DataSet_03_422
PGLYRP4 FOXP3 CRISPR Peripheral_blood Naive Treg 6.17647 2.62678 3.857498e-03 0.132322433 DataSet_03_427
PGLYRP4 IKZF2 shRNA Lymph Hut78 0.55544 -0.848298 1.354252e-02 0.40530138 DataSet_03_429
PGLYRP4 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.538462 -0.893085 0.6271900968 1 DataSet_03_430
PGLYRP4 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 3 1.58496 - - DataSet_03_432
PGLYRP4 SUFU shRNA Mammary_gland HCC1954 cells 40.5 5.33985 0.0009230383 0.2904148 DataSet_03_437
PGLYRP4 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 3.5 1.80735 1.346301e-01 0.90558273 DataSet_03_439
PGLYRP4 SREBF2 siRNA Umbilical_vein HUVEC 2.546 1.34823 3.818162e-01 7.835597e-01 DataSet_03_457
PGLYRP4 LIN28A siRNA Mammary_gland MCF7M 3.17554 1.667 7.098110e-02 0.3718692 DataSet_03_469
PGLYRP4 LIN28A siRNA Mammary_gland MCF7M 3.17554 1.667 7.098110e-02 0.3718692 DataSet_03_470
PGLYRP4 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.642857 -0.63743 0.0792468 0.5049739 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate CNOT7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PGLYRP4
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines