Gene Overview
Target Gene: PLEKHG6
NCBI Official Symbol: PLEKHG6
Entrez ID: 55200
Ensembl ID: ENSG00000008323
Gene Full Name: pleckstrin homology and RhoGEF domain containing G6
Strand: +
Gene Locus: 12p13.31
External Links:

PLEKHG6 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PLEKHG6   
T(co)Fs that Repress PLEKHG6
The Intensity of the Gene Regulated by T(co)Fs:
PLEKHG6-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PLEKHG6 HOXA1 siRNA Lung_fibroblast IMR-90 3.4477 1.78563 0.06839 0.28083 DataSet_01_110
PLEKHG6 ZIC2 siRNA Pancreas PANC1 1.52542 0.60921 - - DataSet_01_121
PLEKHG6 FOXM1 siRNA Central_nervous_system U87 1.50926 0.59384 - - DataSet_01_122
PLEKHG6 TFAP2C shRNA Mammary_gland MCF7 0.50803 -0.97702 5.78971e-10 1.11618e-08 DataSet_01_150
PLEKHG6 TEAD4 shRNA Stomach SNU216 0.58805 -0.766 - - DataSet_01_151
PLEKHG6 ELK1 siRNA Peripheral_blood CD4+ T cells 1.82589 0.8686 0.02521 0.09754 DataSet_01_162
PLEKHG6 NFATC3 siRNA Peripheral_blood CD4+ T cells 1.62068 0.6966 0.0691 0.27406 DataSet_01_166
PLEKHG6 TP53 siRNA Lung SAECs 1.93519 0.95247 0.08284 0.46313 DataSet_01_175
PLEKHG6 TP63 shRNA Bladder UC14 1.86595 0.89991 7.56107e-06 0.00026 DataSet_01_183
PLEKHG6 HIC1 shRNA Mammary_gland HBL100 0.55321 -0.85411 - - DataSet_01_205
PLEKHG6 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 4.37092 2.12794 - - DataSet_01_209
PLEKHG6 EGR3 shRNA Prostate M12 0.65794 -0.60397 0.02902 0.18162 DataSet_01_212
PLEKHG6 SNAI2 shRNA Skin Primary human keratinocytes 1.56349 0.64477 0.01275 0.05458 DataSet_01_225
PLEKHG6 STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.66631 -0.58574 0.00811 0.03247 DataSet_01_239
PLEKHG6 ARNT shRNA Embryo hESC HSF1 1.5591 0.64071 0.1298 0.99999 DataSet_01_240
PLEKHG6 TP53 shRNA Haematopoietic_and_lymphoid_tissue JVM2 1.96785 0.97662 0.00678 0.03637 DataSet_01_286
PLEKHG6 SNAI2 siRNA Mammary_gland MCFDCIS 3.00639 1.58803 0.0119 0.44148 DataSet_01_292
PLEKHG6 TFAP4 siRNA Brain BE(2)-C 0.19261 -2.37627 0.39904 0.51625 DataSet_01_295
PLEKHG6 PTEN shRNA Skin A431 3.37944 1.75679 0.08203 0.23836 DataSet_01_301
PLEKHG6 ARNT siRNA Upper_aerodigestive_tract HSC3 1.50325 0.58809 - - DataSet_01_315
PLEKHG6 TCF7L1 shRNA Colon HCT116 1.63065 0.70545 2e-04 0.00864 DataSet_01_346
PLEKHG6 HIF1A siRNA Oral_cavity OEC-M1 1.85504 0.89145 0.08151 0.85151 DataSet_01_348
PLEKHG6 SAFB2 shRNA Liver HepG2 1.78344 0.83466 0.00406 0.02835 DataSet_02_102
PLEKHG6 FIP1L1 shRNA Liver HepG2 0.38961 -1.3599 0.00156 0.01728 DataSet_02_103
PLEKHG6 TAF15 shRNA Liver HepG2 0.41546 -1.26721 0.00388 0.01819 DataSet_02_106
PLEKHG6 SSB shRNA Liver HepG2 1.75075 0.80797 0.00301 0.01285 DataSet_02_107
PLEKHG6 HNRNPUL1 shRNA Liver HepG2 1.98726 0.99078 0.00471 0.0295 DataSet_02_109
PLEKHG6 GTF2F1 shRNA Liver HepG2 0.47296 -1.08021 0.01582 0.23265 DataSet_02_110
PLEKHG6 U2AF2 shRNA Liver HepG2 0.54419 -0.87783 0.64689 0.75163 DataSet_02_113
PLEKHG6 XRCC5 shRNA Liver HepG2 0.53987 -0.88931 0.04446 0.20217 DataSet_02_114
PLEKHG6 PCBP1 shRNA Liver HepG2 0.60689 -0.72049 0.02597 0.05959 DataSet_02_115
PLEKHG6 TARDBP shRNA Liver HepG2 1.65664 0.72826 0.06399 0.12265 DataSet_02_116
PLEKHG6 PTBP1 shRNA Liver HepG2 0.58919 -0.76318 0.00301 0.01112 DataSet_02_120
PLEKHG6 HNRNPLL shRNA Liver HepG2 2.90442 1.53825 0.00793 0.0296 DataSet_02_125
PLEKHG6 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.57831 -0.79008 0.24876 0.75553 DataSet_02_130
PLEKHG6 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.58242 -0.77987 0.63161 0.72092 DataSet_02_131
PLEKHG6 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.10638 -3.23266 0.03877 0.16019 DataSet_02_132
PLEKHG6 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52747 -0.92283 0.47217 0.6237 DataSet_02_135
PLEKHG6 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.42857 -1.22239 0.3865 0.61375 DataSet_02_137
PLEKHG6 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.26882 -1.8953 0.05345 0.25016 DataSet_02_140
PLEKHG6 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.5914 0.67029 0.23035 0.40796 DataSet_02_142
PLEKHG6 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.49057 1.31647 0.03949 0.08471 DataSet_02_143
PLEKHG6 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25532 -1.96963 0.16439 0.39399 DataSet_02_144
PLEKHG6 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 2.39583 1.26053 0.011 0.51061 DataSet_02_145
PLEKHG6 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.64815 -0.6256 0.53361 0.81892 DataSet_02_146
PLEKHG6 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.84524 0.88381 0.26694 0.55514 DataSet_02_148
PLEKHG6 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 2.54321 1.34665 0.01119 0.19424 DataSet_02_149
PLEKHG6 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 3.04167 1.60486 0.03787 0.24547 DataSet_02_151
PLEKHG6 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.57143 0.65208 0.37437 0.74541 DataSet_02_153
PLEKHG6 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.23171 -2.10962 0.01294 0.22733 DataSet_02_155
PLEKHG6 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.6988 0.76451 0.11328 0.35286 DataSet_02_163
PLEKHG6 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.43011 -1.21723 0.31919 0.49536 DataSet_02_165
PLEKHG6 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 2.54945 1.35019 0.16234 0.28189 DataSet_02_168
PLEKHG6 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48387 -1.04731 0.41125 0.5391 DataSet_02_170
PLEKHG6 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.10753 -3.21723 0.21257 0.41805 DataSet_02_171
PLEKHG6 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.25478 -1.97269 0.3756 1 DataSet_02_174
PLEKHG6 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 1.65263 0.72477 0.85364 1 DataSet_02_176
PLEKHG6 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.47222 -1.08246 0.05286 1 DataSet_02_178
PLEKHG6 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.31169 -1.68182 0.06459 1 DataSet_02_179
PLEKHG6 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52229 -0.93707 0.87474 1 DataSet_02_180
PLEKHG6 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 2.26667 1.18057 0.1814 1 DataSet_02_182
PLEKHG6 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 0.31818 -1.65208 0.21553 1 DataSet_02_184
PLEKHG6 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.2907 -1.78241 0.20943 1 DataSet_02_186
PLEKHG6 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.6686 0.73864 0.29849 1 DataSet_02_187
PLEKHG6 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 1.62857 0.70361 0.54552 1 DataSet_02_190
PLEKHG6 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.76842 0.82246 0.53675 1 DataSet_02_192
PLEKHG6 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 2.29167 1.1964 0.17951 1 DataSet_02_198
PLEKHG6 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.71831 0.78099 0.95592 1 DataSet_02_202
PLEKHG6 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 0.52778 -0.922 0.08905 1 DataSet_02_203
PLEKHG6 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.4359 1.28445 0.68582 1 DataSet_02_204
PLEKHG6 ASCL1 siRNA Lung DMS79 1.71191 0.775602 0.071057985504436 0.723812200913737 DataSet_03_016
PLEKHG6 GATA2 siRNA Uterus Decidual stromal cells 0.584137 -0.77562 0.0700241987149762 0.681425586555076 DataSet_03_100
PLEKHG6 HNF4a siRNA Liver HepG2 0.373436 -1.42107 0.0020718426152484 0.31595599882538 DataSet_03_126
PLEKHG6 KLF5 siRNA Stomach YCC3 0.619656 -0.690462 0.000869674566748536 0.0507781951780997 DataSet_03_151
PLEKHG6 MEF2D shRNA Liver HuH7 1.96083 0.971468 - - DataSet_03_162
PLEKHG6 MEF2D siRNA Liver HuH7 0.60615 -0.722253 - - DataSet_03_163
PLEKHG6 MITF siRNA Skin SK-MEL-5 0.565121 -0.823367 0.000417510278409001 0.00168839418809569 DataSet_03_168
PLEKHG6 MTA2 siRNA Stomach SGC-7901 0.581035 -0.783302 - - DataSet_03_169
PLEKHG6 MYB siRNA Cord_Blood CD34+ progenitor cells 1.64553 0.718553 - - DataSet_03_170
PLEKHG6 MYC siRNA Colon HT29 2.17578 1.12153 - - DataSet_03_177
PLEKHG6 NR2F2 siRNA Uterus Primary eutopic stromal cells 0.591243 -0.758176 0.254640427661261 0.99947668859931 DataSet_03_202
PLEKHG6 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.598108 -0.741521 0.000553501457479429 0.00374133122276906 DataSet_03_211
PLEKHG6 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 12.7 3.66676 - - DataSet_03_246
PLEKHG6 STAT3 CRISPR Embryo hESC 0.0798431 -3.64669 0.0128107343421582 0.0704012689936291 DataSet_03_258
PLEKHG6 STAT6 siRNA Umbilical_vein HUVEC 0.469697 -1.0902 0.1774632334007 0.837635960915423 DataSet_03_264
PLEKHG6 TFAP2C siRNA Mammary_gland MCF7 1.50641 0.591116 0.0452332529737741 0.372917121106038 DataSet_03_274
PLEKHG6 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.98039 0.985786 0.218406964249097 0.915844825866729 DataSet_04_003
PLEKHG6 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.42029 -1.25054 0.140939023438573 0.228765461477042 DataSet_04_004
PLEKHG6 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.19672 1.13535 0.00777439670826745 0.452673378973461 DataSet_04_008
PLEKHG6 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.23077 1.69188 0.0489627645503913 0.130789215399482 DataSet_04_010
PLEKHG6 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.06667 1.61667 0.0415361576854058 0.0788196387370635 DataSet_04_012
PLEKHG6 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.635294 -0.654503 0.428132764216473 0.883765156532286 DataSet_04_013
PLEKHG6 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 332.067 8.37533 0.0320446879303915 0.102749843166801 DataSet_04_014
PLEKHG6 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.352941 -1.5025 0.0768318525800469 0.221801720626172 DataSet_04_019
PLEKHG6 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.612245 -0.707819 0.413093435904975 0.705038474807137 DataSet_04_020
PLEKHG6 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.90756 0.931731 0.684836401347431 0.870130916471994 DataSet_04_022
PLEKHG6 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.333333 -1.58496 0.00100647319918313 0.113567209536072 DataSet_04_023
PLEKHG6 ANXA2 CRISPR Liver HepG2 0.547059 -0.870232 0.263626581088409 0.756714522136274 DataSet_04_024
PLEKHG6 E4F1 CRISPR Liver HepG2 1.58006 0.659978 0.0147864558702808 0.244807869652322 DataSet_04_028
PLEKHG6 NFX1 CRISPR Liver HepG2 0.550984 -0.859918 0.00433409802031356 0.0230248080531791 DataSet_04_032
PLEKHG6 CALR shRNA Liver HepG2 0.423459 -1.2397 0.000799667028226242 0.00899898824684527 DataSet_04_053
PLEKHG6 CNOT7 shRNA Liver HepG2 0.279709 -1.838 0.0010827896132143 0.00713015415137121 DataSet_04_051
PLEKHG6 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.661017 -0.597241 0.227163298294457 0.428606083499061 DataSet_04_048
PLEKHG6 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.01961 1.01408 0.079778348969219 0.608853428815846 DataSet_04_047
PLEKHG6 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.488235 -1.03435 0.15664131381105 0.32608063240712 DataSet_04_046
PLEKHG6 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.573248 -0.802768 0.133343170049227 1 DataSet_04_077
PLEKHG6 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.585987 -0.771059 0.136951308561649 0.261471788211892 DataSet_04_049
PLEKHG6 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.61146 0.688373 0.0173061602305274 0.146406863870886 DataSet_02_38
PLEKHG6 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.64331 1.40235 0.0253754945079652 0.0724697528742761 DataSet_02_14
PLEKHG6 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.98726 0.990781 0.0387005414035837 0.109617027578729 DataSet_02_34
PLEKHG6 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 10.8471 3.43924 0.0988179769075199 0.579506422749596 DataSet_02_45
PLEKHG6 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.24841 1.69973 0.00699761760338715 0.0326462079837655 DataSet_02_35
PLEKHG6 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.63057 0.705379 0.445049886864277 0.604605716963688 DataSet_02_47
PLEKHG6 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.470297 -1.08836 0.192686875100078 0.607344586137107 DataSet_02_49
PLEKHG6 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.636943 -0.650765 0.189838236861833 0.35649546831546 DataSet_02_43
PLEKHG6 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.636943 -0.650765 0.0573909839459316 0.125852389629649 DataSet_02_33
PLEKHG6 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 3.2093 1.68226 0.00595824414950903 0.0677706161179461 DataSet_04_061
PLEKHG6 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.418605 -1.25634 0.412508219660849 0.788863409180685 DataSet_04_063
PLEKHG6 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 6.53333 2.70782 0.041400991136927 0.0877498422560275 DataSet_04_059
PLEKHG6 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.639535 -0.644905 0.217573736797999 0.592632298383423 DataSet_04_065
PLEKHG6 SMARCA4 siRNA Colon HCT116 0.552313 -0.856443 1.865161e-02 0.1548209 DataSet_03_302
PLEKHG6 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.62438 0.699888 3.226573e-02 0.6330193 DataSet_03_306
PLEKHG6 SNAI2 shRNA Pancreas KLM1 1.75102 0.808195 1.673712e-02 0.19558548 DataSet_03_307
PLEKHG6 EZH2 knockdown Colon HCT116 0.648555 -0.6247 0.115987417 0.8488990 DataSet_03_334
PLEKHG6 ARID3B CRISPR Colon HCT15 1.5884 0.66757 - - DataSet_03_335
PLEKHG6 ZFX siRNA Prostate C4-2B 0.648902 -0.623928 1.302712e-02 2.706679e-02 DataSet_03_348
PLEKHG6 EZH2 shRNA Mammary_gland LM2 1.67581 0.744858 5.716098e-01 8.680543e-01 DataSet_03_350
PLEKHG6 SKI CRISPR Blood HL60 3 1.58496 3.374388e-01 0.615851377 DataSet_03_351
PLEKHG6 CREBBP CRISPR Brain U5-NPC 0.388889 -1.36257 0.4869622835 0.7526951 DataSet_03_356
PLEKHG6 PTPN14 CRISPR Brain U5-NPC 0.541667 -0.884523 6.038378e-01 0.74542334 DataSet_03_357
PLEKHG6 TP53 CRISPR Brain U5-NPC 0.333333 -1.58496 3.706825e-01 5.002607e-01 DataSet_03_358
PLEKHG6 NCOA2 siRNA Uterus endometrial stromal cells 0.631579 -0.662965 0.3284528686 1 DataSet_03_360
PLEKHG6 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 1.82177 0.865343 7.427447e-04 2.720405e-03 DataSet_03_362
PLEKHG6 MYC siRNA Peripheral_blood T lymphocyte 2.0648 1.046 3.632964e-01 0.621620710 DataSet_03_363
PLEKHG6 EP300 shRNA Mammary_gland MCF10AT 0.454545 -1.1375 1.596602e-01 0.386610559 DataSet_03_364
PLEKHG6 ABL1 shRNA Liver HuH7 2.86851 1.5203 2.088966e-03 0.0099978242 DataSet_03_367
PLEKHG6 TPR shRNA Bone_marrow U2OS 1.63572 0.709926 5.213165e-02 3.426880e-01 DataSet_03_370
PLEKHG6 NFKB2 siRNA Bone_marrow U2OS 3.71429 1.89308 1.007083e-02 0.14066963 DataSet_03_381
PLEKHG6 DNMT1 siRNA Skin Human melanoma cells 1.55795 0.639652 3.895823e-01 5.017296e-01 DataSet_03_382
PLEKHG6 YY1 shRNA Brain GSC1517 16 4 - - DataSet_03_384
PLEKHG6 YY1 shRNA Brain GSC23 0.375 -1.41504 - - DataSet_03_385
PLEKHG6 NFKBIA shRNA Bone_marrow U2OS 0.000702741 -10.4747 4.168404e-01 0.87005461 DataSet_03_389
PLEKHG6 ILF2 siRNA Stomach SGC-7901 1.88889 0.917538 0.3231076831 0.51804000 DataSet_03_393
PLEKHG6 BMI1 shRNA Bile_duct QBC-939 0.649766 -0.622009 1.024638e-04 0.0020095623 DataSet_03_395
PLEKHG6 JAZF1 siRNA Cervix HeLa Kyoto 0.647593 -0.626842 1.804345e-01 0.766122791 DataSet_03_396
PLEKHG6 IKZF2 CRISPR Lymph CAR T Cell 0.583193 -0.777954 7.075517e-01 0.933682283 DataSet_03_397
PLEKHG6 TLE4 CRISPR Lymph CAR T Cell 1.58291 0.662582 6.955883e-01 0.88978919 DataSet_03_398
PLEKHG6 RELA CRISPR Brain T30 19.76 4.30451 0.3472506302 0.8400824 DataSet_03_399
PLEKHG6 HMGA1 shRNA Bile_duct HUCCT1 1.60552 0.683043 1.043498e-02 0.123521532 DataSet_03_400
PLEKHG6 EHF shRNA Stomach MKN7 3.91223 1.96799 - - DataSet_03_402
PLEKHG6 TFAP2A knockout Embryo H9 0.51949 -0.944831 2.292462e-03 0.03643826 DataSet_03_405
PLEKHG6 MAP3K7 shRNA Prostate LNCaP 0.640584 -0.642541 4.749182e-01 6.812760e-01 DataSet_03_408
PLEKHG6 USP22 shRNA Liver HuH7 0.200669 -2.31711 - - DataSet_03_411
PLEKHG6 E2F6 shRNA Liver HuH7 1.76153 0.816826 - - DataSet_03_412
PLEKHG6 E2F2 siRNA Prostate LNCaP 1.6 0.678072 7.866707e-03 5.565720e-02 DataSet_03_414
PLEKHG6 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2.8 1.48543 7.144597e-02 0.207317218 DataSet_03_418
PLEKHG6 FOXK2 shRNA Ovary OVCAR-5 0.407216 -1.29613 6.434778e-03 0.09101657 DataSet_03_419
PLEKHG6 PRDM1 CRISPR Lymph CD8+ T cells 2.5 1.32193 - - DataSet_03_421
PLEKHG6 FOXQ1 CRISPR Lymph Primary CD4+ T cells 3.75 1.90689 - - DataSet_03_422
PLEKHG6 MAEL CRISPR Liver Alexander cells 0.582418 -0.779874 - - DataSet_03_423
PLEKHG6 FOXP3 CRISPR Peripheral_blood Naive Treg 2.5 1.32193 6.220010e-01 0.816445063 DataSet_03_427
PLEKHG6 IKZF2 shRNA Lymph Hut78 4.66263 2.22114 1.621707e-02 0.40530138 DataSet_03_429
PLEKHG6 USP7 shRNA Skin xenograft cells 0.402299 -1.31366 0.15552081 0.4348960 DataSet_03_431
PLEKHG6 HMG20A siRNA Mammary_gland MDA-MB-231 2 1 0.3454174513 0.5341362 DataSet_03_442
PLEKHG6 CAMTA1 knockout Embryo_kidney HEK293T 2.66667 1.41504 3.009824e-01 0.44365395 DataSet_03_448
PLEKHG6 CBX2 siRNA Mammary_gland MCF7 0.524358 -0.931375 2.570221e-02 0.0639098771 DataSet_03_451
PLEKHG6 SMARCA2 shRNA Lung HCC2302 18.5506 4.2134 1.126398e-15 6.348920e-14 DataSet_03_455
PLEKHG6 ARID1A shRNA Bile_duct MMNK1 0.502023 -0.994175 8.024340e-03 0.087065084 DataSet_03_458
PLEKHG6 SOX9 knockout Liver HuH7 2.14085 1.09818 6.058767e-04 6.512118e-03 DataSet_03_463
PLEKHG6 PARP1 knockout Embryo_kidney HEK293a 0.586592 -0.76957 5.780460e-01 6.807188e-01 DataSet_03_464
PLEKHG6 SMARCA1 Cas13 Embryo_kidney HEK293T 2 1 - - DataSet_03_466
PLEKHG6 SMARCA1 shRNA Embryo_kidney HEK293T 0.5 -1 - - DataSet_03_468
PLEKHG6 EZH2 siRNA Prostate LNCaP 0.583745 -0.776589 - - DataSet_03_472
PLEKHG6 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.98039 0.985786 0.1772403 0.8700248 DataSet_04_071
Regulation Region
 
T(co)Fs that significantly regulate YY1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PLEKHG6
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines