Gene Overview
Target Gene: TIMP4
NCBI Official Symbol: TIMP4
Entrez ID: 7079
Ensembl ID: ENSG00000157150
Gene Full Name: TIMP metallopeptidase inhibitor 4
Strand: -
Gene Locus: 3p25.2
External Links:

TIMP4 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate TIMP4   
T(co)Fs that Repress TIMP4
The Intensity of the Gene Regulated by T(co)Fs:
TIMP4-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
TIMP4 SPDEF shRNA Mammary_gland MCF7 0.3081 -1.69851 0.44696 0.99999 DataSet_01_107
TIMP4 HOXA1 siRNA Lung_fibroblast IMR-90 0.51489 -0.95766 0.01071 0.11033 DataSet_01_110
TIMP4 ZIC2 siRNA Pancreas PANC1 1.69634 0.76242 - - DataSet_01_121
TIMP4 FOXM1 siRNA Central_nervous_system U87 20.1651 4.33379 - - DataSet_01_122
TIMP4 ID1 shRNA Neuroepithelium GSC2 2.01807 1.01298 5.41474e-12 1.95271e-10 DataSet_01_133
TIMP4 ID1 shRNA Neuroepithelium GSC8 2.75427 1.46167 3.7052e-13 1.28724e-11 DataSet_01_134
TIMP4 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.19856 1.13656 0.03382 0.56522 DataSet_01_137
TIMP4 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.92663 0.94608 0.09775 0.99993 DataSet_01_138
TIMP4 POLR3A siRNA Mammary_gland MCF7 0.14992 -2.73771 - - DataSet_01_139
TIMP4 TFAP2C shRNA Mammary_gland MCF7 0.43952 -1.18599 1.3814e-12 6.92862e-11 DataSet_01_150
TIMP4 HOXB7 siRNA Pancreas MIA PaCa-2 0.55839 -0.84066 0.04473 0.61361 DataSet_01_169
TIMP4 TP53 siRNA Lung SAECs 1.7172 0.78006 0.16995 0.58466 DataSet_01_175
TIMP4 CREB1 shRNA Parotid_gland H3118 MEC 0.085 -3.55644 0.00267 0.1173 DataSet_01_194
TIMP4 CREB1 shRNA Parotid_gland HSY 0.39031 -1.35731 0.0449 0.56168 DataSet_01_195
TIMP4 TP63 siRNA Immortalized_keratinocyte HaCaT RG 2.88 1.52607 - - DataSet_01_196
TIMP4 TP63 siRNA Immortalized_keratinocyte HaCaT 4.29787 2.10362 - - DataSet_01_200
TIMP4 TP63 siRNA Head_and_neck SCC-012 0.59829 -0.74108 - - DataSet_01_201
TIMP4 TP63 siRNA Head_and_neck SCC-6 0.58031 -0.7851 - - DataSet_01_202
TIMP4 XBP1 shRNA Mammary_gland T47D 0.65749 -0.60496 0.00405 0.01626 DataSet_01_203
TIMP4 XBP1 shRNA Mammary_gland MDA-MB-231 2.77491 1.47244 4.62558e-06 0.00154 DataSet_01_204
TIMP4 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 1.67335 0.74274 - - DataSet_01_208
TIMP4 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.438 -1.191 - - DataSet_01_210
TIMP4 EGR3 shRNA Prostate M12 1.65519 0.727 0.00637 0.09495 DataSet_01_212
TIMP4 KLF9 siRNA Liver HepG2 0.50878 -0.97487 1.56935e-05 0.00024 DataSet_01_222
TIMP4 KLF2 shRNA Bone_marrow RPMI8226 2.84894 1.51043 0.32728 0.84407 DataSet_01_226
TIMP4 IRX1 shRNA Bone_marrow 143B 3.03543 1.6019 0.00021 0.0189 DataSet_01_227
TIMP4 NFYB siRNA Bone_marrow U2OS ER-HA-E2F1 0.61595 -0.69912 0.23918 0.67232 DataSet_01_238
TIMP4 SOX4 shRNA Mammary_gland MDA-MB-231 1.71725 0.7801 0.00966 0.121 DataSet_01_260
TIMP4 MYT1L shRNA Fetal_spinal_cord SPC04 0.53768 -0.89518 0.00666 0.14741 DataSet_01_264
TIMP4 MEF2A shRNA Fetal_spinal_cord SPC04 2.25978 1.17618 0.00022 0.58122 DataSet_01_265
TIMP4 ESRRA shRNA Embryo_kidney 293T 0.44345 -1.17314 0.11792 0.7178 DataSet_01_280
TIMP4 MSX1 siRNA Tooth Dental Pulp Cells 1.68396 0.75186 7.76593e-05 0.00087 DataSet_01_281
TIMP4 POSTN shRNA Brain GSC272 2.40979 1.26891 0.36608 0.68878 DataSet_01_293
TIMP4 TFAP4 siRNA Brain BE(2)-C 0.2087 -2.26047 0.35478 0.51625 DataSet_01_295
TIMP4 PTEN shRNA Skin A431 0.31095 -1.68525 0.00103 0.0655 DataSet_01_301
TIMP4 NR2E1 shRNA Neuroepithelium PBT003 0.66481 -0.58898 0.1999 0.62046 DataSet_01_306
TIMP4 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.32668 -1.61405 0.18607 0.40579 DataSet_01_313
TIMP4 GATA3 siRNA Oral_cavity OEC-M1 2.61669 1.38774 0.04357 0.99787 DataSet_01_347
TIMP4 HIF1A siRNA Oral_cavity OEC-M1 2.05423 1.0386 0.10205 0.85151 DataSet_01_348
TIMP4 SOX2 shRNA Neuroepithelium HF2303 0.63 -0.66658 0.16722 1 DataSet_01_349
TIMP4 SOX17 siRNA Umbilical_vein HUVEC 4.70255 2.23344 - - DataSet_01_360
TIMP4 SAFB2 shRNA Liver HepG2 0.16667 -2.58496 0.00212 0.02492 DataSet_02_102
TIMP4 FIP1L1 shRNA Liver HepG2 1.66667 0.73697 0.06762 0.13378 DataSet_02_103
TIMP4 HDGF shRNA Liver HepG2 0.42857 -1.22239 0.04733 0.16938 DataSet_02_104
TIMP4 SSB shRNA Liver HepG2 0.53846 -0.89308 0.18849 0.25242 DataSet_02_107
TIMP4 ZNF622 shRNA Liver HepG2 18.5 4.20945 0.07321 0.12026 DataSet_02_108
TIMP4 HNRNPUL1 shRNA Liver HepG2 1.875 0.90689 0.05392 0.11152 DataSet_02_109
TIMP4 BCLAF1 shRNA Liver HepG2 5 2.32193 0.11624 0.21395 DataSet_02_112
TIMP4 PCBP1 shRNA Liver HepG2 3.66667 1.87447 0.03236 0.06881 DataSet_02_115
TIMP4 TARDBP shRNA Liver HepG2 0.1875 -2.41504 0.02414 0.0629 DataSet_02_116
TIMP4 SUB1 shRNA Liver HepG2 4.33333 2.11548 0.0261 0.16451 DataSet_02_117
TIMP4 RBM25 shRNA Liver HepG2 1.66667 0.73697 0.09537 0.16712 DataSet_02_119
TIMP4 PTBP1 shRNA Liver HepG2 4.66667 2.22239 0.67988 0.72121 DataSet_02_120
TIMP4 RBM34 shRNA Liver HepG2 2.33333 1.22239 0.50894 0.76556 DataSet_02_121
TIMP4 FUS shRNA Liver HepG2 4.33333 2.11548 0.46614 0.6393 DataSet_02_124
TIMP4 PRPF4 shRNA Liver HepG2 0.23077 -2.11548 0.27269 0.3983 DataSet_02_128
TIMP4 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.5625 -0.83007 0.14667 0.72262 DataSet_02_130
TIMP4 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.08995 0.49149 DataSet_02_139
TIMP4 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.02688 0.51061 DataSet_02_145
TIMP4 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.87049 0.97283 DataSet_02_146
TIMP4 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.11809 0.2454 DataSet_02_147
TIMP4 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.11875 0.55902 DataSet_02_150
TIMP4 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.11445 0.31158 DataSet_02_151
TIMP4 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.45907 0.72536 DataSet_02_152
TIMP4 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.22222 -2.16993 0.16788 0.61444 DataSet_02_153
TIMP4 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 5 2.32193 0.41337 0.69579 DataSet_02_156
TIMP4 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.12367 0.28988 DataSet_02_160
TIMP4 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.625 -0.67807 0.39064 0.60204 DataSet_02_163
TIMP4 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.11849 0.28526 DataSet_02_165
TIMP4 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.47827 0.59933 DataSet_02_170
TIMP4 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.16737 1 DataSet_02_176
TIMP4 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.27831 1 DataSet_02_177
TIMP4 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.1885 1 DataSet_02_178
TIMP4 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.36364 -1.45943 0.74775 1 DataSet_02_181
TIMP4 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 4.33333 2.11548 0.16129 1 DataSet_02_182
TIMP4 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 1.57143 0.65208 0.46802 1 DataSet_02_185
TIMP4 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 4.75 2.24793 0.14261 1 DataSet_02_191
TIMP4 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 3.5 1.80735 0.14083 1 DataSet_02_192
TIMP4 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 3.375 1.75489 0.55113 1 DataSet_02_193
TIMP4 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.24779 1 DataSet_02_194
TIMP4 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.25 1.16993 0.93098 1 DataSet_02_197
TIMP4 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.63636 -0.65208 0.5827 1 DataSet_02_198
TIMP4 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 3.125 1.64386 0.29731 1 DataSet_02_199
TIMP4 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.31026 1 DataSet_02_200
TIMP4 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.39678 1 DataSet_02_201
TIMP4 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.13271 1 DataSet_02_202
TIMP4 ZFX siRNA Mammary_gland MCF7 1.82031 0.86419 0.01665 0.11529 DataSet_02_206
TIMP4 AR siRNA Prostate abl cells 0.456693 -1.1307 0.504235033645385 0.999852161656754 DataSet_03_004
TIMP4 AR siRNA Prostate LNCaP 1.81081 0.856636 0.308101512302102 1 DataSet_03_005
TIMP4 ARID1A siRNA Oral_cavity SAS cells 0.52824 -0.920735 0.108483623195742 0.600476515599457 DataSet_03_013
TIMP4 ASCL1 siRNA Lung DMS79 9.78571 3.29068 0.0341410378334564 0.63771390312078 DataSet_03_016
TIMP4 BCL6 siRNA Lymph Pfeiffer DLBCL 2.53803 1.34371 0.167423590382992 0.645508848734979 DataSet_03_026
TIMP4 BCL6 siRNA Central_nervous_system U87 1.56662 0.647655 0.000168184504094381 0.0190686051799034 DataSet_03_027
TIMP4 CASP8AP2 siRNA Bone_marrow hTERT-RPE1 1.66496 0.735485 0.000236769164076936 0.0282496215560911 DataSet_03_030
TIMP4 CEBPB siRNA Embryo hESC 0.452722 -1.1433 0.0859735878167603 0.442364858805427 DataSet_03_049
TIMP4 EBF1 siRNA White_adipose_tissue Fully differentiated adipocytes 0.592519 -0.755066 0.222961162344125 0.95691689190661 DataSet_03_064
TIMP4 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.34036 -1.55487 - - DataSet_03_096
TIMP4 GATA2 siRNA Lymph Lymphatic endothelial cells 1.55763 0.63935 3.85699526933099e-06 0.000103728553626263 DataSet_03_101
TIMP4 GATA6 siRNA Stomach YCC3 2.06016 1.04276 0.377405656902111 0.869290998562152 DataSet_03_110
TIMP4 HINFP siRNA Bone_marrow hTERT-RPE1 1.51344 0.597833 0.0137071466939947 0.184238737695197 DataSet_03_122
TIMP4 HMGA1 siRNA Mammary_gland MDA-MB-231 0.33834 -1.56346 1.56843818945213e-09 3.20420084835716e-07 DataSet_03_124
TIMP4 HNF4a siRNA Liver HepG2 1.87838 0.909488 0.767804689450578 0.970047504110121 DataSet_03_126
TIMP4 HOXC4 siRNA Skin Fibroblast 0.582245 -0.780302 1.64972201940516e-05 0.00891932520554021 DataSet_03_128
TIMP4 Klf4 siRNA Skin Primary neonatal keratinocytes 0.662013 -0.595068 0.00730415767331256 0.035274650850933 DataSet_03_147
TIMP4 KLF5 siRNA Stomach AGS 1.93202 0.950108 0.395970921984565 0.796539741344705 DataSet_03_149
TIMP4 KLF5 siRNA Stomach KatoIII 0.269541 -1.89142 0.0698170332420164 0.484711760943405 DataSet_03_150
TIMP4 KLF5 siRNA Stomach YCC3 2.8366 1.50416 0.146786858530224 0.506910481976485 DataSet_03_151
TIMP4 LHX9 siRNA Skin Fibroblast 0.592704 -0.754617 2.92699167184857e-05 0.010661027982032 DataSet_03_152
TIMP4 MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.650671 -0.62 0.326833371937249 1 DataSet_03_155
TIMP4 MEF2D shRNA Liver HuH7 3.3224 1.73223 - - DataSet_03_162
TIMP4 MITF siRNA Skin SK-MEL-5 0.654816 -0.610839 0.00941470559129367 0.0202787284894249 DataSet_03_168
TIMP4 MTA2 siRNA Stomach SGC-7901 2.84793 1.50991 - - DataSet_03_169
TIMP4 MYB siRNA Cord_Blood CD34+ progenitor cells 0.414187 -1.27164 - - DataSet_03_170
TIMP4 MYC siRNA Colon HT29 1.93156 0.949765 - - DataSet_03_177
TIMP4 NPAT siRNA Bone_marrow hTERT-RPE1 1.71051 0.774423 0.000102560445986346 0.0176729316117388 DataSet_03_200
TIMP4 PHB shRNA Embryo Embryonic stem cells (ESCs) 2.3627 1.24044 0.000350572679866625 0.00276361535584702 DataSet_03_211
TIMP4 SMAD7 siRNA Mammary_gland MCF7 1.69369 0.760171 0.00287984965885732 0.99858912864726 DataSet_03_234
TIMP4 SOX11 siRNA Lung_fibroblast NHLF 1.69229 0.758979 0.160795693595884 0.572933882078046 DataSet_03_237
TIMP4 SOX11 siRNA Lung_fibroblast NHLF 1.95111 0.964293 0.245483716848592 0.61591290502065 DataSet_03_238
TIMP4 SOX2 siRNA Embryo 2102Ep 0.494863 -1.0149 1.17461859725148e-05 0.000731184373331867 DataSet_03_242
TIMP4 SOX2 siRNA Embryo NTera-2 0.390206 -1.35769 7.43027109734854e-07 0.000239688807182471 DataSet_03_243
TIMP4 SOX2 CRISPR Seminoma-like TCam-2 0.234969 -2.08946 2.15810943999537e-05 0.061987040504233 DataSet_03_244
TIMP4 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 4.375 2.12928 - - DataSet_03_246
TIMP4 SP1 siRNA Cervix HeLa 2.09349 1.06591 8.97760188984662e-05 0.00171740255233771 DataSet_03_249
TIMP4 STAT1 knockout Liver Huh-7.5 2.09748 1.06866 6.93635935155714e-05 0.00885579780818475 DataSet_03_257
TIMP4 TFE3 siRNA Kidney UOK257-2 0.57155 -0.807047 - - DataSet_03_275
TIMP4 TWIST1 siRNA Bone_marrow MSCs 1.63717 0.711203 - - DataSet_03_283
TIMP4 TWIST2 siRNA Skin Fibroblast 0.596268 -0.745966 7.68250882956369e-05 0.0109464814668982 DataSet_03_284
TIMP4 ZNF165 siRNA Mammary_gland WHIM12 1.51474 0.599073 0.776537821993653 0.999997668745677 DataSet_03_289
TIMP4 ZNF746 siRNA Colon HCT116 0.5637 -0.827 - - DataSet_03_293
TIMP4 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.0505399805242182 0.484722079354532 DataSet_04_008
TIMP4 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.91667 0.9386 0.238520950312585 0.846595731090813 DataSet_04_013
TIMP4 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 295.286 8.20597 0.000285049729605621 0.00602882365262342 DataSet_04_014
TIMP4 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.473684 -1.078 0.0124959230702227 0.0896731605765743 DataSet_04_018
TIMP4 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.8 0.847997 0.0281867458522089 0.395800493182546 DataSet_04_020
TIMP4 ANXA2 CRISPR Liver HepG2 1.91667 0.9386 0.395077944186825 0.811170962015774 DataSet_04_024
TIMP4 ERN1 CRISPR Liver HepG2 1.75 0.807355 0.222988897140357 0.424658206597218 DataSet_04_029
TIMP4 MECP2 CRISPR Liver HepG2 1.75 0.807355 0.224883851567179 0.50897585929821 DataSet_04_031
TIMP4 SRPK2 CRISPR Liver HepG2 0.5 -1 0.303228402028323 0.503898739305244 DataSet_04_037
TIMP4 WRN shRNA Liver HepG2 0.5 -1 0.297512944173635 0.527476476760972 DataSet_04_038
TIMP4 ZC3H8 shRNA Liver HepG2 1.8 0.847997 0.072904825909812 0.224979876459435 DataSet_04_040
TIMP4 DNMT3B CRISPR Liver HepG2 2.5 1.32193 0.733174471942216 0.89440895185978 DataSet_04_044
TIMP4 PAN2 CRISPR Liver HepG2 9 3.16992 0.07636023005853 0.191101322514317 DataSet_04_066
TIMP4 SEPT11 CRISPR Liver HepG2 0.222222 -2.16992 0.522914236715893 0.751422448858315 DataSet_04_068
TIMP4 CALR shRNA Liver HepG2 0.375 -1.41504 0.644508727075649 0.767986035806643 DataSet_04_053
TIMP4 CCAR1 shRNA Liver HepG2 7.4 2.88753 0.0525184898875627 0.134691574834527 DataSet_04_054
TIMP4 PRPF6 shRNA Liver HepG2 4.33333 2.11548 0.474177584391088 0.685276012389635 DataSet_04_056
TIMP4 YBX3 shRNA Liver HepG2 0.458333 -1.12553 0.31137681143407 0.505214516905359 DataSet_02_98
TIMP4 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.515152 -0.956931 0.181310924576577 0.372570994804957 DataSet_04_048
TIMP4 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.285714 -1.80735 0.579813934286062 0.916673059794322 DataSet_04_047
TIMP4 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.851239810463875 0.980962826879223 DataSet_04_076
TIMP4 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.795868909595498 0.956636905922333 DataSet_04_073
TIMP4 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.716986106799352 0.918638634192046 DataSet_04_075
TIMP4 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2 1 0.759335334092337 0.871964866445864 DataSet_04_049
TIMP4 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.653846 -0.612977 0.322075087264546 0.582841921343197 DataSet_02_38
TIMP4 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.288462 -1.79355 0.0659882245746558 0.146999445240287 DataSet_02_14
TIMP4 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.211538 -2.24101 0.0312658208343649 0.0944210670641241 DataSet_02_34
TIMP4 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.2 1.1375 0.724043396515895 0.919868919436023 DataSet_02_75
TIMP4 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.57692 0.657112 0.106015483851024 0.217471078054358 DataSet_02_35
TIMP4 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.442308 -1.17688 0.119135343388341 0.428285890993828 DataSet_02_32
TIMP4 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.634615 -0.656046 0.178687671076064 0.313112367764444 DataSet_02_47
TIMP4 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.58333 0.662965 0.784201584603559 0.967904963627294 DataSet_02_49
TIMP4 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.647210769020719 0.805116702813048 DataSet_04_061
TIMP4 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 6.66667 2.73697 0.43751871496757 0.571599759674375 DataSet_04_059
TIMP4 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.430228876888123 0.678425361205628 DataSet_04_062
TIMP4 EZH2 siRNA Uterus Hec-1A 1.63429 0.708667 1.211180e-05 1.549026e-03 DataSet_03_314
TIMP4 SMARCA4 siRNA Colon HCT116 0.422153 -1.24416 2.871628e-03 0.1301247 DataSet_03_302
TIMP4 ELF3 CRISPR Bile_duct HBDEC2 3.44681 1.78526 1.469801e-06 1.395685e-04 DataSet_03_304
TIMP4 AEBP1 siRNA Central_nervous_system U87MG 0.423036 -1.24115 2.165878e-02 0.9446842 DataSet_03_338
TIMP4 BCL3 siRNA Central_nervous_system U87 0.654758 -0.610967 2.209543e-05 8.055093e-04 DataSet_03_336
TIMP4 TET1 CRISPR Mammary_gland MDA-MB-231 0.243727 -2.03666 5.972770e-04 8.967423e-03 DataSet_03_347
TIMP4 ETV5 knockdown Colon HT29 0.151724 -2.72048 2.340638e-04 0.030461033 DataSet_03_353
TIMP4 TET1 CRISPR Mammary_gland Hs578T 0.138363 -2.85347 7.081348e-02 1.857906e-01 DataSet_03_355
TIMP4 PTPN14 CRISPR Brain U5-NPC 0.0342334 -4.86845 2.941398e-04 0.08420420 DataSet_03_357
TIMP4 TP53 CRISPR Brain U5-NPC 1.7384 0.797757 5.567130e-01 6.396962e-01 DataSet_03_358
TIMP4 MYC siRNA Peripheral_blood T lymphocyte 3.18233 1.67008 2.081167e-01 0.492769628 DataSet_03_363
TIMP4 ZNF148 shRNA Mammary_gland MDA-MB-231 0.220641 -2.18023 1.827560e-02 0.098699981 DataSet_03_366
TIMP4 ABL1 shRNA Liver HuH7 1.95978 0.970695 9.058671e-05 0.0015493512 DataSet_03_367
TIMP4 ZNF213 siRNA Mammary_gland MCF7 2.21306 1.14604 7.306539e-01 8.876319e-01 DataSet_03_376
TIMP4 ZBTB7A siRNA Stomach BGC823 2.30416 1.20424 - - DataSet_03_380
TIMP4 DNMT1 siRNA Skin Human melanoma cells 1.6662 0.736557 4.957804e-06 6.677953e-05 DataSet_03_382
TIMP4 NFKBIA shRNA Bone_marrow U2OS 0.0144404 -6.11374 8.660898e-01 0.94301422 DataSet_03_389
TIMP4 YY1 knockdown Liver HepG2 2.625 1.39232 2.132400e-01 3.883719e-01 DataSet_03_390
TIMP4 KDM5A CRISPR Lung GLC16 0.406949 -1.29708 1.971483e-02 0.065030781 DataSet_03_392
TIMP4 ILF2 siRNA Stomach SGC-7901 1.57927 0.659256 0.4316248943 0.64560645 DataSet_03_393
TIMP4 RELA CRISPR Brain T30 2.2465 1.16768 0.2675981868 0.8400824 DataSet_03_399
TIMP4 HMGA1 shRNA Bile_duct HUCCT1 2.49406 1.3185 1.916049e-04 0.017507959 DataSet_03_400
TIMP4 EHF shRNA Stomach MKN7 10.6453 3.41215 - - DataSet_03_402
TIMP4 CHD1 shRNA Prostate LNCaP 0.555556 -0.847997 6.416393e-01 9.413332e-01 DataSet_03_407
TIMP4 MAP3K7 shRNA Prostate LNCaP 0.444444 -1.16992 3.823276e-01 6.082515e-01 DataSet_03_408
TIMP4 USP22 shRNA Liver HuH7 2.69195 1.42865 - - DataSet_03_411
TIMP4 ZKSCAN3 CRISPR Colon HCT116 0.266667 -1.90689 2.933874e-01 0.629422305 DataSet_03_415
TIMP4 STAT5B CRISPR Embryo_kidney HEK293 0.625 -0.678072 2.337952e-01 0.665084591 DataSet_03_424
TIMP4 FOXP3 CRISPR Peripheral_blood Naive Treg 4 2 2.199621e-01 0.572632521 DataSet_03_427
TIMP4 LHX2 shRNA Bone_marrow ES-derived RPE cells 1.55128 0.633461 3.656665e-01 1.000000e+00 DataSet_03_428
TIMP4 USP7 shRNA Skin xenograft cells 0.529004 -0.918649 0.35398332 0.4901191 DataSet_03_431
TIMP4 EP300 knockout Pancreas HPAF-II orthotopic cells 0.518931 -0.946386 1.284141e-05 4.368873e-04 DataSet_03_436
TIMP4 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 4.78846 2.25956 2.672732e-03 0.28288507 DataSet_03_439
TIMP4 HMG20A siRNA Mammary_gland MDA-MB-231 0.649279 -0.623091 0.0245795117 0.2031949 DataSet_03_442
TIMP4 PHF14 siRNA Mammary_gland MDA-MB-231 0.263041 -1.92664 0.0004011676 0.1688577 DataSet_03_443
TIMP4 PURA siRNA Cervix HeLa 1.72561 0.787106 5.227428e-02 0.212115397 DataSet_03_444
TIMP4 CAMTA1 knockout Embryo_kidney HEK293T 7 2.80735 3.179474e-02 0.15484598 DataSet_03_448
TIMP4 RELB CRISPR Colon SW480 1.77778 0.830075 9.977159e-02 2.847317e-01 DataSet_03_449
TIMP4 CBX2 siRNA Mammary_gland MDA-MB-231 0.469682 -1.09024 1.376511e-01 3.053755e-01 DataSet_03_450
TIMP4 CBX2 siRNA Mammary_gland MCF7 0.302353 -1.72569 3.958801e-01 0.5634579287 DataSet_03_451
TIMP4 ARID1A shRNA Bile_duct MMNK1 0.375386 -1.41355 8.221634e-02 0.300373498 DataSet_03_458
TIMP4 IRF2 shRNA Cord_Blood CD34+ cells 3 1.58496 - - DataSet_03_460
TIMP4 SOX9 knockout Liver HuH7 0.109541 -3.19046 1.093195e-04 2.232532e-03 DataSet_03_463
TIMP4 PARP1 knockout Embryo_kidney HEK293a 0.485095 -1.04366 7.970584e-02 1.700681e-01 DataSet_03_464
TIMP4 SMARCA1 Cas13 Embryo_kidney HEK293T 3.6 1.848 - - DataSet_03_466
TIMP4 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.6 0.678072 - - DataSet_03_467
TIMP4 SMARCA1 shRNA Embryo_kidney HEK293T 0.4 -1.32193 - - DataSet_03_468
TIMP4 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.285714 -1.80736 0.638025 0.9792695 DataSet_04_071
Regulation Region
 
T(co)Fs that significantly regulate BCL11A by the evidences of both expression and ChIP-seq/motif
Expression Atlas of TIMP4
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines