Gene Overview
Target Gene: UNC13A
NCBI Official Symbol: UNC13A
Entrez ID: 23025
Ensembl ID: ENSG00000130477
Gene Full Name: unc-13 homolog A
Strand: -
Gene Locus: 19p13.11
External Links:

UNC13A Significantly Regulated by These T(co)Fs

T(co)Fs that Activate UNC13A   
T(co)Fs that Repress UNC13A
The Intensity of the Gene Regulated by T(co)Fs:
UNC13A-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
UNC13A ID1 siRNA Lung H1650 0.55762 -0.84265 0.00715 0.32206 DataSet_01_118
UNC13A ZIC2 siRNA Pancreas PANC1 0.32296 -1.63058 - - DataSet_01_121
UNC13A EGR4 siRNA Lung SBC-5 0.63099 -0.66432 0.07685 0.41392 DataSet_01_132
UNC13A REST siRNA Uterus Smooth muscle cells 2.34452 1.2293 0.0043 0.99996 DataSet_01_136
UNC13A POLR3A siRNA Mammary_gland MCF7 1.78481 0.83577 - - DataSet_01_139
UNC13A REST siRNA Adrenal_gland H295R/TR 2.75609 1.46262 4.35139e-08 0.00013 DataSet_01_145
UNC13A SF1 siRNA Adrenal_gland H295R/TR 0.53383 -0.90554 9.7166e-07 0.00013 DataSet_01_146
UNC13A JUN siRNA Peripheral_blood CD4+ T cells 1.53624 0.61941 0.20012 0.44517 DataSet_01_164
UNC13A HOXB7 siRNA Pancreas MIA PaCa-2 0.57753 -0.79203 0.1598 0.65301 DataSet_01_169
UNC13A FOSL1 siRNA Mammary_gland BT549 1.57732 0.65747 0.00041 0.02405 DataSet_01_171
UNC13A TP53 siRNA Lung SAECs 0.61032 -0.71237 0.14514 0.55988 DataSet_01_175
UNC13A GABPA shRNA Prostate C4-2B 1740.93 10.7656 0.23882 0.43934 DataSet_01_190
UNC13A GABPA shRNA Prostate LNCaP 860.992 9.74986 0.46727 0.7048 DataSet_01_191
UNC13A GATA2 siRNA Prostate LNCaP 0.63804 -0.64828 0.15872 0.27284 DataSet_01_193
UNC13A CREB1 shRNA Parotid_gland H3118 MEC 0.59663 -0.7451 0.10048 0.42292 DataSet_01_194
UNC13A CREB1 shRNA Parotid_gland HSY 1.75253 0.80944 0.15824 0.81968 DataSet_01_195
UNC13A TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.52303 0.60694 - - DataSet_01_197
UNC13A TP63 siRNA Head_and_neck SCC-1 2.73077 1.44931 - - DataSet_01_198
UNC13A TP63 siRNA Head_and_neck SCC-012 3.02404 1.59648 - - DataSet_01_201
UNC13A TP63 siRNA Head_and_neck SCC-6 0.45211 -1.14526 - - DataSet_01_202
UNC13A MITF shRNA Skin COLO829 1.54683 0.62931 0.22131 0.43388 DataSet_01_207
UNC13A FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.25966 -1.9453 - - DataSet_01_208
UNC13A FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.61746 -0.69557 - - DataSet_01_209
UNC13A FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.81753 1.49443 - - DataSet_01_210
UNC13A REST siRNA Prostate LNCaP 30.1401 4.91361 0.00081 0.07176 DataSet_01_211
UNC13A LIN28A siRNA Embryo H9 0.31131 -1.68358 0.00052 0.00839 DataSet_01_215
UNC13A EGR2 siRNA Muscle A673 1.79699 0.84559 0.33711 0.8205 DataSet_01_242
UNC13A EGR2 siRNA Neuroepithelium SK-N-MC 2.19258 1.13263 0.26868 0.83208 DataSet_01_243
UNC13A TWIST1 shRNA Stomach CAF14 2.43504 1.28395 0.04697 0.99996 DataSet_01_252
UNC13A TWIST1 shRNA Stomach CAF32 0.42068 -1.24921 0.00609 0.03961 DataSet_01_253
UNC13A AR shRNA Prostate CWR22Pc 1.86939 0.90256 0.00071 0.01308 DataSet_01_278
UNC13A POSTN shRNA Brain GSC272 2.59329 1.37479 0.10126 0.54761 DataSet_01_293
UNC13A TFAP4 siRNA Brain BE(2)-C 0.0899 -3.47552 0.19091 0.51625 DataSet_01_295
UNC13A PTEN shRNA Skin A431 0.43113 -1.21381 0.10468 0.27139 DataSet_01_301
UNC13A PTEN shRNA Lung HCC827 2.37839 1.24999 0.045 0.54477 DataSet_01_302
UNC13A PTEN shRNA Mammary_gland SKBR3 1.96484 0.97441 0.98549 0.99568 DataSet_01_303
UNC13A NR2E1 shRNA Neuroepithelium PBT003 1.73589 0.79568 0.00383 0.42474 DataSet_01_306
UNC13A REST siRNA Skin NHEK 96.0356 6.5855 3.24865e-05 0.00586 DataSet_01_337
UNC13A REST siRNA Skin NHEK 205.581 7.68357 1.05278e-08 0.00019 DataSet_01_338
UNC13A GATA3 siRNA Oral_cavity OEC-M1 2.16754 1.11606 0.01424 0.68576 DataSet_01_347
UNC13A HIF1A siRNA Oral_cavity OEC-M1 1.55428 0.63624 0.12798 0.85151 DataSet_01_348
UNC13A CDX2 siRNA Colon COLO320 3.95822 1.98485 - - DataSet_01_357
UNC13A PAX3 shRNA Soft_tissue Rh30 2.7249 1.4462 - - DataSet_01_359
UNC13A RBM17 shRNA Liver HepG2 2 1 0.11621 0.38013 DataSet_02_100
UNC13A FIP1L1 shRNA Liver HepG2 0.58824 -0.76553 0.13271 0.21862 DataSet_02_103
UNC13A HDGF shRNA Liver HepG2 2.28 1.18903 0.02527 0.12766 DataSet_02_104
UNC13A U2AF2 shRNA Liver HepG2 0.13725 -2.86507 0.00137 0.04622 DataSet_02_105
UNC13A TAF15 shRNA Liver HepG2 3.5 1.80735 0.00156 0.01265 DataSet_02_106
UNC13A ZNF622 shRNA Liver HepG2 0.4 -1.32193 0.00221 0.0118 DataSet_02_108
UNC13A HNRNPUL1 shRNA Liver HepG2 3.51282 1.81263 0.0109 0.0431 DataSet_02_109
UNC13A GTF2F1 shRNA Liver HepG2 0.58824 -0.76553 0.06473 0.33872 DataSet_02_110
UNC13A BCLAF1 shRNA Liver HepG2 3.67105 1.87619 0.00017 0.02312 DataSet_02_112
UNC13A U2AF2 shRNA Liver HepG2 0.12069 -3.05063 0.0015 0.0514 DataSet_02_113
UNC13A XRCC5 shRNA Liver HepG2 0.58824 -0.76553 0.06219 0.22802 DataSet_02_114
UNC13A PCBP1 shRNA Liver HepG2 1.88462 0.91427 0.02896 0.06365 DataSet_02_115
UNC13A TARDBP shRNA Liver HepG2 1.89744 0.92405 0.00895 0.03531 DataSet_02_116
UNC13A PTBP1 shRNA Liver HepG2 3.86538 1.95061 0.00119 0.00746 DataSet_02_120
UNC13A EWSR1 shRNA Liver HepG2 4.7 2.23266 0.01016 0.06144 DataSet_02_122
UNC13A PCBP2 shRNA Liver HepG2 2.27451 1.18556 0.02035 0.10547 DataSet_02_123
UNC13A FUS shRNA Liver HepG2 0.64706 -0.62803 0.23482 0.42525 DataSet_02_124
UNC13A SNRNP70 shRNA Liver HepG2 0.28205 -1.82597 0.00162 0.03109 DataSet_02_126
UNC13A PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.89333 0.92093 0.06154 0.12946 DataSet_02_131
UNC13A TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.93333 0.95109 0.55292 0.74268 DataSet_02_140
UNC13A NONO shRNA Haematopoietic_and_lymphoid_tissue K562 2.46154 1.29956 0.01494 0.19424 DataSet_02_149
UNC13A RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 1.98485 0.98903 0.02809 0.2379 DataSet_02_151
UNC13A HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.83333 0.87447 0.02603 0.51515 DataSet_02_156
UNC13A PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.76744 2.25322 5e-04 0.0795 DataSet_02_158
UNC13A RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62222 -0.6845 0.03632 0.21725 DataSet_02_166
UNC13A EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47273 -1.08092 0.00042 0.22555 DataSet_02_167
UNC13A VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.61268 -0.7068 0.20191 1 DataSet_02_179
UNC13A BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.59459 -0.75002 0.07869 1 DataSet_02_186
UNC13A UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.56579 -0.82166 0.23784 1 DataSet_02_198
UNC13A RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.71795 0.78069 0.05937 1 DataSet_02_204
UNC13A BCL6 siRNA Lymph Pfeiffer DLBCL 1.89977 0.925822 0.10262929213985 0.575650341365367 DataSet_03_026
UNC13A CEBPB siRNA Embryo hESC 2.35698 1.23694 0.150850521077213 0.528748288629946 DataSet_03_049
UNC13A GATA4 siRNA Stomach YCC3 1.51383 0.598199 0.220939222263542 0.747868290410219 DataSet_03_107
UNC13A GATA6 siRNA Stomach KatoIII 1.75841 0.814273 0.190730297041622 0.701216390851866 DataSet_03_109
UNC13A GATA6 siRNA Stomach YCC3 0.433238 -1.20677 0.0892631103807576 0.707616607959491 DataSet_03_110
UNC13A HINFP siRNA Bone_marrow U2OS 2.15138 1.10526 1.75467180724503e-05 0.00520069114304641 DataSet_03_123
UNC13A KLF5 siRNA Stomach YCC3 0.417227 -1.2611 0.0549511515399021 0.346354445392584 DataSet_03_151
UNC13A MTA2 siRNA Stomach SGC-7901 0.652448 -0.616065 - - DataSet_03_169
UNC13A PHB shRNA Embryo Embryonic stem cells (ESCs) 0.458074 -1.12635 0.0217443460105597 0.0583053260102364 DataSet_03_211
UNC13A REST siRNA Adrenal_gland H295R/TR 2.84748 1.50969 3.50704524384522e-08 0.000104326363888509 DataSet_03_228
UNC13A SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.625 -0.678072 - - DataSet_03_246
UNC13A STAT3 CRISPR Embryo hESC 4.00689 2.00248 0.0421016841126384 0.114779363169478 DataSet_03_258
UNC13A STAT6 siRNA Umbilical_vein HUVEC 0.566802 -0.819084 0.09668892541623 0.808832946068239 DataSet_03_264
UNC13A TET2 siRNA Prostate DU145 1.52401 0.60787 - - DataSet_03_271
UNC13A TFAP2C siRNA Mammary_gland MCF7 0.553766 -0.852652 0.196092376732786 0.547709159724573 DataSet_03_274
UNC13A TFE3 siRNA Kidney UOK257-2 0.661834 -0.595459 - - DataSet_03_275
UNC13A CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.519608 -0.944505 0.00847963987862953 0.0579213038651605 DataSet_04_002
UNC13A CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 5.11268 2.35408 0.000464667352521826 0.0187062860053472 DataSet_04_004
UNC13A EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.88235 0.912537 0.0836716414115437 0.49256691822214 DataSet_04_008
UNC13A FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.75 1.90689 0.00935765331145707 0.0661270614703137 DataSet_04_010
UNC13A NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 47.337 5.5649 0.044875831805654 0.127551638119805 DataSet_04_014
UNC13A PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.1875 1.12928 0.059341093632789 0.811810847774913 DataSet_04_016
UNC13A SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.540541 -0.887525 0.00251535633717999 0.0786343354168621 DataSet_04_018
UNC13A SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.94624 0.960687 0.0152681648779536 0.118406459019399 DataSet_04_019
UNC13A SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.55435 0.636309 0.00362692854747725 0.394951331771279 DataSet_04_020
UNC13A YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.441558 -1.17932 0.174819345449868 0.579368577062628 DataSet_04_022
UNC13A ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.64 -0.643856 0.15494478965005 0.304327206287033 DataSet_04_023
UNC13A ANXA2 CRISPR Liver HepG2 1.69893 0.764622 0.0161378851342947 0.577364782982721 DataSet_04_024
UNC13A APTX CRISPR Liver HepG2 1.8913 0.919381 0.014927721148576 0.425890326589601 DataSet_04_025
UNC13A CIZ1 CRISPR Liver HepG2 2.63077 1.39549 0.012240400928957 0.181344272100339 DataSet_04_026
UNC13A E4F1 CRISPR Liver HepG2 1.63158 0.706269 0.00723482149255682 0.206933669323673 DataSet_04_028
UNC13A ERN1 CRISPR Liver HepG2 1.92105 0.941897 0.0569611264322966 0.203491207451637 DataSet_04_029
UNC13A MECP2 CRISPR Liver HepG2 1.80263 0.850105 0.0629293313432479 0.308520340807415 DataSet_04_031
UNC13A NFX1 CRISPR Liver HepG2 34 5.08746 2.53371473070135e-06 0.0107080024071796 DataSet_04_032
UNC13A SRPK2 CRISPR Liver HepG2 1.64474 0.717857 0.0963196842078265 0.273907264755605 DataSet_04_037
UNC13A YBX1 CRISPR Liver HepG2 1.61539 0.691878 0.0803381081049503 0.972884761036538 DataSet_04_039
UNC13A ZC3H8 shRNA Liver HepG2 2.10345 1.07276 0.124807506183284 0.298262331710319 DataSet_04_040
UNC13A ZNF574 CRISPR Liver HepG2 0.65812 -0.603578 0.0191513325192923 0.0898464010806405 DataSet_04_041
UNC13A ACTN4 CRISPR Liver HepG2 0.283582 -1.81816 0.0240958220535779 0.0859207251780931 DataSet_04_042
UNC13A DDX20 CRISPR Liver HepG2 1.69737 0.7633 0.133698844294949 0.268248745651555 DataSet_04_043
UNC13A DNMT3B CRISPR Liver HepG2 1.60526 0.68281 0.025140812271963 0.159796073845019 DataSet_04_044
UNC13A SEPT11 CRISPR Liver HepG2 1.63208 0.706708 0.0143633830391221 0.119977042039522 DataSet_04_068
UNC13A ABT1 shRNA Liver HepG2 0.413793 -1.27302 0.205827147579786 0.322442301731363 DataSet_04_052
UNC13A CALR shRNA Liver HepG2 2.11905 1.08342 0.0164512303985133 0.0514914657452335 DataSet_04_053
UNC13A CNOT7 shRNA Liver HepG2 0.166667 -2.58496 0.183428394220711 0.271573110669392 DataSet_04_051
UNC13A NPM1 shRNA Liver HepG2 1.72414 0.785875 0.147319708805739 0.540421404425433 DataSet_04_058
UNC13A PRPF6 shRNA Liver HepG2 26.549 4.73059 3.04492180290111e-06 0.0210821866264412 DataSet_04_056
UNC13A NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.04301 1.0307 0.0013607703824114 0.0408255447908373 DataSet_04_046
UNC13A SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.621622 -0.685891 0.380577799137416 1 DataSet_04_077
UNC13A SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.56757 0.648528 0.20586408796562 0.353473324285605 DataSet_04_049
UNC13A ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.73913 0.798366 0.0809179267850799 0.184176845189686 DataSet_02_34
UNC13A HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.32609 1.73383 0.0749549379926989 0.548541954098249 DataSet_02_45
UNC13A LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.93478 0.952172 0.222099481901383 0.379710959099743 DataSet_02_35
UNC13A NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.6413 1.40125 0.149626998541713 0.451761073277781 DataSet_02_32
UNC13A SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.657534 -0.604862 0.425804935926577 0.794220125431659 DataSet_02_49
UNC13A TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.478261 -1.06413 0.091521585815159 0.181005757121911 DataSet_02_33
UNC13A ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.5625 1.83289 0.0131205262989581 0.0612843136644717 DataSet_04_060
UNC13A CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.37333 1.24691 0.00942825184988642 0.0657619338252891 DataSet_04_064
UNC13A CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.06061 1.04307 0.0177395555699542 0.101542955939886 DataSet_04_061
UNC13A PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 4.72381 2.23995 0.000353201431336959 0.195605415730804 DataSet_04_065
UNC13A UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.53061 0.614109 0.0804027103285961 0.270820823579085 DataSet_04_062
UNC13A CNOT3 shRNA Lung A549 1.51144 0.595923 1.120054e-01 0.8830540 DataSet_03_340
UNC13A SMARCA4 siRNA Colon HCT116 1.88936 0.917898 9.177630e-02 9.571744e-01 DataSet_03_301
UNC13A PRMT1 shRNA Lung A549 1.74243 0.801098 - - DataSet_03_342
UNC13A ZFX siRNA Mammary_gland MCF7 1.50199 0.586877 5.522734e-02 1.813040e-01 DataSet_03_349
UNC13A SKI CRISPR Blood HL60 0.642857 -0.63743 2.180687e-01 0.615851377 DataSet_03_351
UNC13A ESR1 siRNA Mammary_gland MCF7 0.65865 -0.602417 3.517578e-02 0.1486469429 DataSet_03_352
UNC13A ETV5 knockdown Colon HT29 0.425287 -1.23349 6.462991e-03 0.094409347 DataSet_03_353
UNC13A PARP1 siRNA Prostate LNCaP 1.58876 0.667898 4.482066e-01 0.706796466 DataSet_03_354
UNC13A TET1 CRISPR Mammary_gland Hs578T 0.225159 -2.15099 3.032575e-01 5.012600e-01 DataSet_03_355
UNC13A CREBBP CRISPR Brain U5-NPC 1.72727 0.788496 0.1490924385 0.7490853 DataSet_03_356
UNC13A PTPN14 CRISPR Brain U5-NPC 0.571429 -0.807355 3.488119e-01 0.56731100 DataSet_03_357
UNC13A TP53 CRISPR Brain U5-NPC 20.0455 4.3252 1.497549e-04 9.420080e-02 DataSet_03_358
UNC13A NCOA3 siRNA Mammary_gland MDA-MB-231 0.664138 -0.590444 6.578408e-01 0.9568977 DataSet_03_361
UNC13A ABL1 shRNA Liver HuH7 0.6326 -0.660633 7.958957e-03 0.0256423022 DataSet_03_367
UNC13A DNMT3A knockout Embryo_kidney HEK293T 0.654802 -0.610869 - - DataSet_03_369
UNC13A ZFP36L1 siRNA Urinary_bladder J82 2 1 - - DataSet_03_371
UNC13A BHLHE40 shRNA Cervix HeLaS3 2.05988 1.04256 5.958185e-01 0.92972028 DataSet_03_372
UNC13A ZNF213 siRNA Mammary_gland MCF7 0.00793838 -6.97694 8.507181e-02 5.057283e-01 DataSet_03_376
UNC13A DDX5 shRNA Stomach HGC-27 4.09091 2.03242 - - DataSet_03_379
UNC13A DNMT1 siRNA Skin Human melanoma cells 2.08153 1.05765 1.751475e-06 3.788219e-05 DataSet_03_382
UNC13A TCF19 CRISPR Oral_squamous CAL27 5.78375 2.53201 7.498748e-04 0.0163640566 DataSet_03_383
UNC13A KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.86155 1.5168 0.2612862457 0.8388073 DataSet_03_387
UNC13A TRIM8 siRNA Mammary_gland MCF7 0.333333 -1.58496 6.218100e-03 0.0383851430 DataSet_03_388
UNC13A ILF2 siRNA Stomach SGC-7901 2.15653 1.10871 0.0755186836 0.21075323 DataSet_03_393
UNC13A ASXL1 CRISPR Embryo iPSC 2.3273 1.21866 0.0909839677 0.8048302 DataSet_03_394
UNC13A RELA CRISPR Brain T30 0.131379 -2.92819 0.3319795493 0.8400824 DataSet_03_399
UNC13A HMGA1 shRNA Bile_duct HUCCT1 1.91228 0.935294 8.193978e-03 0.110842812 DataSet_03_400
UNC13A EHF shRNA Stomach MKN7 0.0553163 -4.17615 - - DataSet_03_402
UNC13A CDK7 shRNA Bone_marrow D458 10.5 3.39232 3.503434e-02 0.27450886 DataSet_03_404
UNC13A STRAP knockout Nerve SK-N-AS 15.5878 3.96235 - - DataSet_03_409
UNC13A SIRT1 siRNA Pancreas PANC1 0.578947 -0.788496 5.086112e-02 0.138208822 DataSet_03_410
UNC13A NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 11.75 3.55459 1.048641e-04 0.003766242 DataSet_03_418
UNC13A FOXK2 shRNA Ovary OVCAR-5 0.0582524 -4.10154 7.815553e-03 0.09617284 DataSet_03_419
UNC13A BRD4 CRISPR Lymph CD8+ T cells 0.2 -2.32193 - - DataSet_03_420
UNC13A PRDM1 CRISPR Lymph CD8+ T cells 0.6 -0.736966 - - DataSet_03_421
UNC13A FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.470588 -1.08746 - - DataSet_03_422
UNC13A MAEL CRISPR Liver Alexander cells 0.376471 -1.40939 - - DataSet_03_423
UNC13A STAT5B CRISPR Embryo_kidney HEK293 0.485095 -1.04366 1.679690e-03 0.205626398 DataSet_03_424
UNC13A FOXP3 CRISPR Peripheral_blood Naive Treg 3.16667 1.66297 4.651689e-02 0.303704149 DataSet_03_427
UNC13A USP7 shRNA Skin xenograft cells 0.515829 -0.955036 0.27025194 0.4348960 DataSet_03_431
UNC13A PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.357143 -1.48543 - - DataSet_03_432
UNC13A POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.69234 0.75902 8.616488e-02 0.500930674 DataSet_03_434
UNC13A POU2AF1 CRISPR Lymph SUDHL4 0.6001 -0.736725 3.347500e-01 0.445514196 DataSet_03_435
UNC13A EP300 knockout Pancreas HPAF-II orthotopic cells 0.590625 -0.759686 4.388362e-01 6.297444e-01 DataSet_03_436
UNC13A SUFU shRNA Mammary_gland HCC1954 cells 1.58333 0.662965 0.1876069622 0.6455297 DataSet_03_437
UNC13A CIC knockout Brain Immortalized Astrocyte Cells 0.314634 -1.66825 4.027141e-02 3.452150e-01 DataSet_03_438
UNC13A FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 1.88235 0.912537 7.258712e-02 0.90558273 DataSet_03_439
UNC13A HMG20A siRNA Mammary_gland MDA-MB-231 0.367232 -1.44524 0.0129909709 0.1740877 DataSet_03_442
UNC13A PHF14 siRNA Mammary_gland MDA-MB-231 0.553672 -0.852896 0.0589410513 0.4509894 DataSet_03_443
UNC13A CAMTA1 knockout Embryo_kidney HEK293T 2.59459 1.37551 3.392259e-02 0.15912997 DataSet_03_448
UNC13A CBX2 siRNA Mammary_gland MCF7 0.141697 -2.81912 1.764570e-02 0.0475670171 DataSet_03_451
UNC13A OGT siRNA Embryo BeWo cells 1.61429 0.690896 3.311487e-02 0.52550251 DataSet_03_453
UNC13A ZFP36L1 CRISPR Lung NCI-H1876 0.206946 -2.27267 3.270814e-01 0.992381486 DataSet_03_454
UNC13A SREBF2 siRNA Umbilical_vein HUVEC 3.02329 1.59612 3.150195e-01 7.451290e-01 DataSet_03_457
UNC13A HAND1 siRNA Placenta HPMVEC 0.662791 -0.593375 2.258647e-01 0.9463341 DataSet_03_459
UNC13A PARP1 knockout Embryo_kidney HEK293a 1.52707 0.610762 8.719545e-02 1.828312e-01 DataSet_03_464
UNC13A STAT3 shRNA Liver HepG2 1.54545 0.628031 2.564647e-01 0.5909364897 DataSet_03_465
UNC13A SMARCA1 Cas13 Embryo_kidney HEK293T 0.191176 -2.38702 - - DataSet_03_466
UNC13A SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.15441 1.10729 - - DataSet_03_467
UNC13A SMARCA1 shRNA Embryo_kidney HEK293T 0.595588 -0.747613 - - DataSet_03_468
UNC13A WHSC1 siRNA Prostate PC3 1.55814 0.639824 2.016487e-01 0.43721886 DataSet_03_471
UNC13A EZH2 siRNA Prostate LNCaP 2.71048 1.43855 - - DataSet_03_472
UNC13A EZH2 siRNA Umbilical_vein HUVEC 2.63158 1.39593 4.665945e-03 0.106210771 DataSet_03_473
UNC13A HMGB2 knockdown Umbilical_vein HUVEC 0.625 -0.678072 4.330199e-05 0.02495801 DataSet_03_476
UNC13A CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 0.519608 -0.944505 0.01538367 0.056232531 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate REST by the evidences of both expression and ChIP-seq/motif
Expression Atlas of UNC13A
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines