Gene Overview
Target Gene: USP18
NCBI Official Symbol: USP18
Entrez ID: 11274
Ensembl ID: ENSG00000184979
Gene Full Name: ubiquitin specific peptidase 18
Strand: +
Gene Locus: 22q11.21
External Links:

USP18 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate USP18   
T(co)Fs that Repress USP18
The Intensity of the Gene Regulated by T(co)Fs:
USP18-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
USP18 HNF1B shRNA Ovary RMG2 2.98209 1.57633 7e-04 0.00314 DataSet_01_103
USP18 FOXA1 shRNA Prostate 22RV1 0.6475 -0.62704 - - DataSet_01_105
USP18 SPDEF shRNA Mammary_gland MCF7 0.65223 -0.61655 0.85394 0.99999 DataSet_01_107
USP18 ARID1A shRNA Ovary OSE4 0.41798 -1.2585 - - DataSet_01_108
USP18 HOXA1 siRNA Lung_fibroblast IMR-90 2.90867 1.54036 0.00176 0.0433 DataSet_01_110
USP18 ID1 siRNA Lung A549 2.90958 1.54081 0.0045 0.11413 DataSet_01_117
USP18 ID1 siRNA Lung H1650 0.44731 -1.16065 0.13919 0.49283 DataSet_01_118
USP18 ZIC2 siRNA Pancreas PANC1 2.43523 1.28406 - - DataSet_01_121
USP18 SPDEF shRNA Mammary_gland MCF7 2.32307 1.21603 1.19457e-05 0.00583 DataSet_01_135
USP18 POLR3A siRNA Mammary_gland MCF7 0.54848 -0.86649 - - DataSet_01_139
USP18 TAL1 shRNA Umbilical_cord_blood ECFCs 1.87301 0.90536 0.19107 0.7427 DataSet_01_152
USP18 ELK1 siRNA Peripheral_blood CD4+ T cells 56.8545 5.8292 4.41295e-10 8.49686e-07 DataSet_01_162
USP18 JUN siRNA Peripheral_blood CD4+ T cells 32654.9 14.995 0.00015 0.00469 DataSet_01_164
USP18 MAF siRNA Peripheral_blood CD4+ T cells 13626.2 13.7341 0.00024 0.00994 DataSet_01_165
USP18 NFATC3 siRNA Peripheral_blood CD4+ T cells 11524.3 13.4924 0.00063 0.01836 DataSet_01_166
USP18 JUN siRNA Mammary_gland BT549 1.8112 0.85695 0.00018 0.01887 DataSet_01_172
USP18 TCF4 siRNA Autonomic_ganglia SH-SY5Y 2.11247 1.07893 0.02127 0.11923 DataSet_01_185
USP18 GATA2 siRNA Prostate LNCaP 0.58867 -0.76446 0.00011 0.00113 DataSet_01_193
USP18 TP63 siRNA Head_and_neck SCC-6 5.21235 2.38193 - - DataSet_01_202
USP18 MITF shRNA Skin COLO829 2.96086 1.56602 0.00033 0.01117 DataSet_01_207
USP18 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.6845 0.75232 - - DataSet_01_210
USP18 LIN28A siRNA Embryo H9 0.57221 -0.80539 0.00827 0.04434 DataSet_01_215
USP18 FOXM1 siRNA Mammary_gland MCF7 3.49489 1.80525 0.00385 0.19947 DataSet_01_223
USP18 KLF2 shRNA Bone_marrow RPMI8226 11.0856 3.47062 0.02618 0.54862 DataSet_01_226
USP18 MYC shRNA Soft_tissue HT1080 20.959 4.3895 - - DataSet_01_237
USP18 TWIST1 shRNA Stomach CAF32 0.36472 -1.45514 0.00022 0.0141 DataSet_01_253
USP18 SOX4 shRNA Mammary_gland MDA-MB-231 1.85905 0.89457 0.0386 0.2404 DataSet_01_260
USP18 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 1.65165 0.7239 5.79733e-07 5.85814e-05 DataSet_01_283
USP18 ZIC5 siRNA Skin SK-MEL-28 1.50736 0.59203 - - DataSet_01_285
USP18 POSTN shRNA Brain GSC272 0.09795 -3.3518 0.01706 0.48721 DataSet_01_293
USP18 TFAP4 siRNA Brain BE(2)-C 0.12106 -3.04617 0.25966 0.51625 DataSet_01_295
USP18 ARID1B shRNA Liver IRM90 1.58694 0.66625 2.70952e-05 0.00148 DataSet_01_298
USP18 PTEN shRNA Skin A431 2.11667 1.0818 0.01613 0.11257 DataSet_01_301
USP18 ETV5 siRNA Soft_tissue hADSC 2.59781 1.3773 1.80595e-05 0.00198 DataSet_01_304
USP18 TFAP2C siRNA Lung NCI-H292 2.76822 1.46896 - - DataSet_01_312
USP18 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.57751 -0.79208 0.00161 0.17596 DataSet_01_313
USP18 ARNT siRNA Upper_aerodigestive_tract HSC3 0.57768 -0.79165 - - DataSet_01_315
USP18 ERG siRNA Cervix HeLa 3.8515 1.94542 7.25706e-10 1.11811e-08 DataSet_01_316
USP18 ELK3 shRNA Mammary_gland MDA-MB-231 11.246 3.49134 2.25343e-08 6.69044e-06 DataSet_01_318
USP18 KLF7 siRNA Embryo HCE 0.49661 -1.00983 0.3032 0.66968 DataSet_01_340
USP18 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue MV4-11 0.64379 -0.63535 0.03266 0.99997 DataSet_01_344
USP18 HIF1A siRNA Oral_cavity OEC-M1 1.9549 0.9671 0.04837 0.85151 DataSet_01_348
USP18 FIP1L1 shRNA Liver HepG2 0.50816 -0.97664 0.00065 0.01276 DataSet_02_103
USP18 SSB shRNA Liver HepG2 2.00145 1.00105 0.00137 0.00852 DataSet_02_107
USP18 ZNF622 shRNA Liver HepG2 0.5999 -0.73722 0.00503 0.01841 DataSet_02_108
USP18 RBM39 shRNA Liver HepG2 0.62809 -0.67096 0.14223 0.38034 DataSet_02_111
USP18 U2AF2 shRNA Liver HepG2 0.513 -0.96296 0.10756 0.22642 DataSet_02_113
USP18 PCBP1 shRNA Liver HepG2 0.6099 -0.71336 0.00091 0.01359 DataSet_02_115
USP18 FUS shRNA Liver HepG2 0.60134 -0.73376 0.00324 0.06169 DataSet_02_124
USP18 SNRNP70 shRNA Liver HepG2 0.53638 -0.89866 0.01829 0.06824 DataSet_02_126
USP18 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.50862 -0.97534 0.02189 0.69659 DataSet_02_130
USP18 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.43925 -1.18688 0.01167 0.11215 DataSet_02_132
USP18 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51923 0.60334 0.01753 0.10856 DataSet_02_134
USP18 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.49038 -1.02801 0.12038 0.25969 DataSet_02_135
USP18 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 1.68116 0.74946 0.05361 0.31572 DataSet_02_138
USP18 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.7551 0.81155 0.09024 0.49149 DataSet_02_139
USP18 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.95327 0.96589 0.03395 0.22383 DataSet_02_144
USP18 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65455 0.72643 0.01597 0.47274 DataSet_02_146
USP18 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.06 1.61353 0.01988 0.10601 DataSet_02_147
USP18 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 2.42857 1.28011 0.09672 0.37647 DataSet_02_148
USP18 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.58696 0.66626 0.07275 0.5057 DataSet_02_150
USP18 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 4.1875 2.06609 0.01359 0.25655 DataSet_02_152
USP18 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.63265 0.70722 0.02508 0.43734 DataSet_02_153
USP18 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 2.04225 1.03016 0.01797 0.37537 DataSet_02_154
USP18 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.79208 0.84163 0.0302 0.51515 DataSet_02_156
USP18 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.61972 0.69574 0.01883 0.7666 DataSet_02_157
USP18 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 2.07042 1.04993 0.00602 0.59238 DataSet_02_159
USP18 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 2.95349 1.56242 0.0171 0.13415 DataSet_02_160
USP18 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.76056 0.81604 0.0087 0.66851 DataSet_02_161
USP18 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66355 0.73427 0.16678 0.63907 DataSet_02_162
USP18 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47845 -1.06357 0.59354 0.75296 DataSet_02_163
USP18 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 2.04673 1.03332 0.18577 0.39351 DataSet_02_164
USP18 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 1.7561 0.81237 0.02489 0.20125 DataSet_02_166
USP18 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 1.53659 0.61973 0.10656 0.30203 DataSet_02_171
USP18 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.49821 -1.00518 0.05651 1 DataSet_02_201
USP18 ATF4 siRNA Skin A375 0.616825 -0.697067 0.233437963233213 0.775512819201899 DataSet_03_018
USP18 BCL6 siRNA Mammary_gland MCF7 2.43487 1.28385 0.0684430548173092 0.989541443114508 DataSet_03_024
USP18 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.278873 -1.84232 0.0270965088188268 0.661845522175647 DataSet_03_025
USP18 BCL6 siRNA Lymph Pfeiffer DLBCL 0.553721 -0.852769 0.00354319867015733 0.230414315922694 DataSet_03_026
USP18 BRCA1 siRNA Mammary_gland MCF7 0.525862 -0.927243 0.162355861813531 0.999850583334387 DataSet_03_028
USP18 CEBPA siRNA Mammary_gland MCF7 1.53926 0.622238 0.327993616603851 0.999962793175751 DataSet_03_047
USP18 CENPF siRNA Mammary_gland MCF7 2.17465 1.12078 0.101755713685665 0.999662524742916 DataSet_03_052
USP18 CHEK1 siRNA Mammary_gland MCF7 1.59089 0.669835 0.295174249452738 0.999587656258211 DataSet_03_053
USP18 CTNNB1 siRNA Mammary_gland MCF7 2.73779 1.45301 0.0454812308051449 0.999436862066063 DataSet_03_058
USP18 E2F1 siRNA Mammary_gland MCF7 2.16664 1.11546 0.103080678695811 0.999927373439084 DataSet_03_061
USP18 E2F5 siRNA Mammary_gland MCF7 2.23543 1.16055 0.09237483167282 0.999540347732068 DataSet_03_062
USP18 EBF1 siRNA White_adipose_tissue Fully differentiated adipocytes 1.52448 0.608316 0.0855396533477099 0.834145468899623 DataSet_03_064
USP18 ERF siRNA Mammary_gland MCF7 1.52218 0.606136 0.33974491900854 0.999855523449227 DataSet_03_067
USP18 ESRRA siRNA Mammary_gland MCF7 0.49873 -1.00367 0.135138479467789 0.999964003642835 DataSet_03_072
USP18 ETS1 siRNA Fibroblasts WI38 0.583666 -0.776786 0.0756657460546166 0.245972517095929 DataSet_03_073
USP18 ETS1 siRNA Fibroblasts WI38 0.537437 -0.895833 0.0535138573863076 0.202421272929759 DataSet_03_074
USP18 FOXA1 siRNA Mammary_gland MCF7 0.45116 -1.14829 1.77905633956725e-08 6.07689116107662e-07 DataSet_03_081
USP18 FOXA1 siRNA Mammary_gland MCF7 0.45116 -1.14829 1.77905633956725e-08 6.07689116107662e-07 DataSet_03_082
USP18 GATA3 siRNA Mammary_gland MCF7 1.81879 0.862979 0.189135511766482 0.999831535534034 DataSet_03_102
USP18 GATA6 siRNA Stomach KatoIII 1.61505 0.691582 0.0773423532825087 0.592028511959253 DataSet_03_109
USP18 GFP siRNA Upper_aerodigestive_tract SCC25 1.57005 0.650813 1.47956941629302e-06 0.000135431486253276 DataSet_03_112
USP18 HDAC3 siRNA Mammary_gland MCF7 2.68317 1.42394 0.048772307081362 0.99997791025972 DataSet_03_114
USP18 HDAC5 siRNA Mammary_gland MCF7 2.02463 1.01766 0.130652443366906 0.999966625300244 DataSet_03_115
USP18 HIF1A siRNA Mammary_gland MCF7 1.79215 0.841693 0.198864012483086 0.999966843283762 DataSet_03_119
USP18 HOXB7 siRNA Mammary_gland MCF7 0.541045 -0.886179 0.179028615130508 0.999977683706165 DataSet_03_127
USP18 HSF2 siRNA Mammary_gland MCF7 1.68335 0.751336 0.245365834008025 0.990969613280381 DataSet_03_130
USP18 Klf4 siRNA Skin Primary neonatal keratinocytes 2.049 1.03492 0.00107856652961087 0.00967537622150927 DataSet_03_147
USP18 MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.550953 -0.86 0.479943112252558 1 DataSet_03_155
USP18 MEF2D shRNA Liver HuH7 1.69526 0.761506 - - DataSet_03_162
USP18 MITF siRNA Skin Ma-Mel-15 0.663218 -0.592444 0.102308617167993 0.533956770251131 DataSet_03_166
USP18 MITF siRNA Skin SK-MEL-5 0.500701 -0.997978 1.51122820383161e-05 0.000126638013862793 DataSet_03_168
USP18 MYB siRNA Cord_Blood CD34+ progenitor cells 10.3673 3.37397 - - DataSet_03_170
USP18 MYC siRNA Central_nervous_system DAOY M2.1 0.665989 -0.58643 4.17506222074557e-06 2.45348636065794e-05 DataSet_03_178
USP18 MYCN CRISPR Neuroblastoma CHP-134 0.599111 -0.739105 4.37105006250095e-05 0.0014644262783033 DataSet_03_183
USP18 MYCN CRISPR Neuroblastoma CHP-134 0.599111 -0.739105 4.37105006250095e-05 0.0014644262783033 DataSet_03_184
USP18 MYCN siRNA Brain BE(2)C cells 0.634416 -0.6565 - - DataSet_03_187
USP18 NR4A3 siRNA Pancreas 1.1B4 2.0398 1.02843 2.07705345428495e-07 1.18520084435944e-05 DataSet_03_203
USP18 PBX1 siRNA Mammary_gland LTED 1.78611 0.836822 0.00423104610946334 0.99990029707784 DataSet_03_208
USP18 PCNA siRNA Mammary_gland MCF7 2.27472 1.18569 0.0868939293995503 0.999448838103647 DataSet_03_210
USP18 PRRX1 CRISPR Neuroblastoma 691-MES 0.566075 -0.820934 0.69899812715219 0.970188524433478 DataSet_03_217
USP18 RB1 siRNA Mammary_gland MCF7 2.03945 1.02818 0.127372666716368 0.999890290262508 DataSet_03_219
USP18 RBL2 siRNA Mammary_gland MCF7 4.92205 2.29926 0.00677314798495865 0.999927471951507 DataSet_03_220
USP18 RELA siRNA Fibroblasts WI38 0.664672 -0.589286 0.164783337823691 0.361923051629176 DataSet_03_222
USP18 RELA siRNA Fibroblasts WI38 0.642031 -0.639286 0.0673470574030272 0.163208809241195 DataSet_03_223
USP18 RELB siRNA Pancreas MIA PaCa-2 1.90718 0.931439 0.0192953778527667 0.128089098937485 DataSet_03_225
USP18 RELB siRNA Immortalized_keratinocyte HaCaT 0.607507 -0.719026 0.000712169296045727 0.00627349898655442 DataSet_03_227
USP18 SOX11 siRNA Lung_fibroblast NHLF 1.86695 0.900684 0.0682951193014837 0.431484615764964 DataSet_03_237
USP18 SOX11 siRNA Lung_fibroblast NHLF 2.2848 1.19207 0.0046782127521846 0.178698917802671 DataSet_03_238
USP18 SOX2 siRNA Embryo NTera-2 0.607163 -0.719845 2.13712975306633e-05 0.00247534914334016 DataSet_03_243
USP18 SP100 siRNA Mammary_gland MCF7 0.429133 -1.2205 0.0798367297245591 0.999952086018951 DataSet_03_252
USP18 SRF siRNA Prostate LNCaP 0.578375 -0.789922 2.66701280562652e-06 0.000106754458975679 DataSet_03_254
USP18 STAT5B siRNA Mammary_gland MCF7 2.20495 1.14074 0.0969347253425652 0.999932708473107 DataSet_03_263
USP18 TCEA1 siRNA Mammary_gland MCF7 2.76258 1.46602 0.0440847353835105 0.999762252994287 DataSet_03_266
USP18 TET1 siRNA Embryo NCCIT 0.496831 -1.00917 1.31531174633839e-05 0.00176183740643154 DataSet_03_269
USP18 TET2 siRNA Embryo NCCIT 0.506477 -0.981432 0.000102841202113256 0.00245083834115916 DataSet_03_270
USP18 TET3 siRNA Embryo NCCIT 0.499477 -1.00151 1.21072490401235e-05 0.00225648701831767 DataSet_03_273
USP18 TFAP2C siRNA Mammary_gland MCF7 11.2 3.48542 0.000668395543953872 0.166627547732606 DataSet_03_274
USP18 TP53 siRNA Mammary_gland MCF7 2.18173 1.12547 0.10060148811815 0.999938217444253 DataSet_03_277
USP18 TP63 siRNA Skin Primary neonatal keratinocytes 3.64531 1.86604 0.000409887560631936 0.00623322691396389 DataSet_03_281
USP18 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.54489 0.627505 0.0594165154069168 0.732269517420315 DataSet_03_282
USP18 ZNF750 siRNA Skin Primary neonatal keratinocytes 2.27979 1.1889 0.00410950612899659 0.0533201649031882 DataSet_03_294
USP18 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.6309 0.70567 0.0167421623293711 0.0551929647826577 DataSet_04_004
USP18 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.61972 1.85588 0.0025219458892646 0.0567314874135781 DataSet_04_010
USP18 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.613924 -0.703868 0.0531092806149545 0.0945965998913613 DataSet_04_012
USP18 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 7.67992 2.94109 0.85991598031445 0.910124947856596 DataSet_04_014
USP18 ABT1 shRNA Liver HepG2 0.483296 -1.04902 0.000663156266575119 0.00660002929860857 DataSet_04_052
USP18 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.59067 0.669638 0.0210334133560221 0.3937702583054 DataSet_02_75
USP18 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.657143 -0.605721 0.0562501513869344 0.130678135349281 DataSet_02_47
USP18 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.604082 -0.727185 0.0280101790395992 0.0954731993113565 DataSet_02_43
USP18 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.640816 -0.642017 0.0468331251905091 0.107752022583696 DataSet_02_33
USP18 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.38028 1.75714 0.00125783602234844 0.0232316789055066 DataSet_04_060
USP18 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.06122 1.0435 0.0634868514656413 0.17887505299605 DataSet_04_064
USP18 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 3.875 1.9542 0.0045004907905299 0.0620788589967562 DataSet_04_061
USP18 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.56962 -0.811928 0.0489756618778825 0.100084242343521 DataSet_04_059
USP18 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 1.96364 0.973528 0.00484965563558238 0.0950056968801355 DataSet_04_062
USP18 SMARCA4 siRNA Colon HCT116 1.5398 0.622744 1.651597e-02 0.1503144 DataSet_03_302
USP18 SNAI2 shRNA Pancreas KLM1 0.582116 -0.780622 9.735939e-03 0.16295942 DataSet_03_307
USP18 EZH2 shRNA Mammary_gland MCF7 2.54167 1.34578 2.185067e-07 6.369392e-05 DataSet_03_331
USP18 EZH2 shRNA Mammary_gland LM2 0.577372 -0.792428 1.457155e-02 1.912730e-01 DataSet_03_350
USP18 ETV5 knockdown Colon HT29 0.484058 -1.04675 1.289998e-03 0.049651979 DataSet_03_353
USP18 PTPN14 CRISPR Brain U5-NPC 0.252913 -1.98329 9.146580e-04 0.13815615 DataSet_03_357
USP18 RUNX1 shRNA Haematopoietic_and_lymphoid_tissue OCI-AML5 2.54631 1.34841 1.455498e-02 1.636079e-01 DataSet_03_359
USP18 NCOA2 siRNA Uterus endometrial stromal cells 0.629428 -0.667887 0.1289697526 1 DataSet_03_360
USP18 ZNF148 shRNA Mammary_gland MDA-MB-231 2.913 1.54251 1.641131e-02 0.093157984 DataSet_03_366
USP18 ZFP36L1 siRNA Urinary_bladder J82 2.86806 1.52007 - - DataSet_03_371
USP18 BHLHE40 shRNA Cervix HeLaS3 4.20066 2.07062 2.586334e-01 0.84447131 DataSet_03_372
USP18 E2F1 siRNA Nasopharynx HK1 1.5359 0.619082 5.990685e-03 7.586376e-02 DataSet_03_373
USP18 GLI1 siRNA Skeletal_muscle RMS13 3.31995 1.73116 2.295810e-05 0.004005592 DataSet_03_375
USP18 EZH2 CRISPR Ovary SKOV3 6.02083 2.58996 4.408572e-04 0.0134008087 DataSet_03_378
USP18 DNMT1 siRNA Skin Human melanoma cells 2.04269 1.03047 1.321422e-07 1.264562e-05 DataSet_03_382
USP18 TRIM8 siRNA Mammary_gland MCF7 2.33004 1.22036 3.653845e-02 0.1262026327 DataSet_03_388
USP18 NFKBIA shRNA Bone_marrow U2OS 0.214286 -2.22239 4.970114e-01 0.87005461 DataSet_03_389
USP18 YY1 knockdown Liver HepG2 0.593939 -0.751612 7.931737e-04 4.134858e-03 DataSet_03_390
USP18 ILF2 siRNA Stomach SGC-7901 3.11029 1.63705 0.1125468816 0.27456440 DataSet_03_393
USP18 RELA CRISPR Brain T30 0.556979 -0.844306 0.0817137839 0.8400824 DataSet_03_399
USP18 HMGA1 shRNA Bile_duct HUCCT1 1.71069 0.77458 1.125222e-02 0.128551688 DataSet_03_400
USP18 EHF shRNA Stomach MKN7 0.470679 -1.08719 - - DataSet_03_402
USP18 TFAP2A knockout Embryo H9 3.35294 1.74543 3.393357e-04 0.01961472 DataSet_03_405
USP18 SIRT1 siRNA Pancreas PANC1 2.31698 1.21225 1.030782e-02 0.051417215 DataSet_03_410
USP18 USP22 shRNA Liver HuH7 2.39193 1.25818 - - DataSet_03_411
USP18 FOXK2 shRNA Ovary OVCAR-5 0.537037 -0.896906 8.340973e-02 0.24752127 DataSet_03_419
USP18 PRDM1 CRISPR Lymph CD8+ T cells 7.95633 2.9921 - - DataSet_03_421
USP18 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.620991 -0.687355 - - DataSet_03_422
USP18 MAEL CRISPR Liver Alexander cells 0.443409 -1.17329 - - DataSet_03_423
USP18 FOXP3 CRISPR Peripheral_blood Naive Treg 4.05018 2.01799 5.703561e-01 0.805901609 DataSet_03_427
USP18 USP7 shRNA Skin xenograft cells 0.462449 -1.11263 0.26165082 0.4348960 DataSet_03_431
USP18 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.48927 -1.0313 - - DataSet_03_432
USP18 POU2AF1 CRISPR Lymph SUDHL4 5.345 2.41819 7.670864e-04 0.011213101 DataSet_03_435
USP18 SUFU shRNA Mammary_gland HCC1954 cells 0.561753 -0.831992 0.0334914713 0.4447510 DataSet_03_437
USP18 DAXX shRNA Mammary_gland MDA-MB-231 0.154975 -2.68989 1.630856e-02 0.14192575 DataSet_03_441
USP18 PURA siRNA Cervix HeLa 0.641379 -0.64075 1.252386e-02 0.104838564 DataSet_03_444
USP18 RELB CRISPR Colon SW480 2.53012 1.33921 3.436926e-04 1.277106e-02 DataSet_03_449
USP18 CBX2 siRNA Mammary_gland MDA-MB-231 0.546372 -0.872045 6.238852e-02 1.758567e-01 DataSet_03_450
USP18 CBX2 siRNA Mammary_gland MCF7 3.43032 1.77834 1.515950e-01 0.2655596061 DataSet_03_451
USP18 SMARCA2 shRNA Lung HCC2302 3.92967 1.97441 1.327991e-13 3.126221e-12 DataSet_03_455
USP18 SREBF2 siRNA Umbilical_vein HUVEC 2.00592 1.00427 2.283457e-01 6.746194e-01 DataSet_03_457
USP18 ARID1A shRNA Bile_duct MMNK1 11.357 3.50551 1.404500e-03 0.034316462 DataSet_03_458
USP18 TXNIP shRNA Cord_Blood CD34+ cells 2.8 1.48543 - - DataSet_03_461
USP18 TXNIP shRNA Cord_blood ST3 4.625 2.20945 9.742364e-02 0.3790035454 DataSet_03_462
USP18 LIN28A siRNA Mammary_gland MCF7M 2.21896 1.14989 1.025166e-03 0.1452921 DataSet_03_469
USP18 LIN28A siRNA Mammary_gland MCF7M 2.21896 1.14989 1.025166e-03 0.1452921 DataSet_03_470
Regulation Region
 
T(co)Fs that significantly regulate SP100 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of USP18
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines