Gene Overview
| Target Gene: | Apoa1 |
| NCBI Official Symbol: | Apoa1 |
| Entrez ID: | 11806 |
| Ensembl ID: | ENSMUSG00000032083 |
| Gene Full Name: | apolipoprotein A-I |
| Strand: | + |
| Gene Locus: | 9 A5.2|9 25.36 cM |
| External Links: |
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Apoa1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Apoa1
T(co)Fs
that Repress Apoa1
The Intensity of the Gene Regulated by T(co)Fs:
Apoa1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Apoa1 | Adnp | knockout | Embryo | Whole embryonic body | 16.9885 | 4.08649 | 0.0396564236933065 | 0.393560697834265 | DataSet_11_001 |
| Apoa1 | Atoh1 | knockout | Gastrointestinal_tissue | Intestinal epithelial Lgr5(hi) stem cells | 13.4532 | 3.74988 | 1.8989033940453e-06 | 0.00164989386230616 | DataSet_11_010 |
| Apoa1 | Atoh8 | shRNA | Pancreas | mPAC L20 | 0.530533 | -0.914485 | 0.0920170672768233 | 0.420969999516463 | DataSet_11_011 |
| Apoa1 | Bhlha9 | knockout | Limb | Whole limb bud | 51.5112 | 5.68681 | - | - | DataSet_11_016 |
| Apoa1 | Dmrt1 | knockout | Ovary | Ovary | 0.323705 | -1.62725 | 0.321050170448052 | 0.622254314963057 | DataSet_11_030 |
| Apoa1 | Dmrt1 | knockout | Ovary | Ovary | 0.323705 | -1.62725 | 0.321050170448052 | 0.622254314963057 | DataSet_11_031 |
| Apoa1 | E2f4 | knockout | Brain | Forebrain | 1.88141 | 0.911815 | - | - | DataSet_11_033 |
| Apoa1 | Elf5 | knockout | Mammary_gland | Mammary gland | 0.35575 | -1.49107 | 0.00172962062510246 | 0.175716856245498 | DataSet_11_035 |
| Apoa1 | Foxp1 | knockout | Eye | Lens | 0.201646 | -2.3101 | - | - | DataSet_11_044 |
| Apoa1 | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 1.69927 | 0.764918 | - | - | DataSet_11_054 |
| Apoa1 | Junb | shRNA | Tibialis_anterior_muscle | Tibialis anterior muscle | 1.85676 | 0.892788 | 0.0450122450166935 | 0.213904682278582 | DataSet_11_065 |
| Apoa1 | Lhx8 | knockout | Gonads | Oocytes | 0.262542 | -1.92938 | 0.0753598853079058 | 0.993830266659981 | DataSet_11_069 |
| Apoa1 | Lmx1b | knockout | Kidney | Kidney | 0.279548 | -1.83883 | 0.269898105426489 | 0.61158782933928 | DataSet_11_072 |
| Apoa1 | Mafg | knockout | Embryo | Whole embryo | 0.237362 | -2.07484 | 0.00454851517864406 | 0.531266572865626 | DataSet_11_073 |
| Apoa1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 0.604396 | -0.726435 | - | - | DataSet_11_074 |
| Apoa1 | Nhlh2 | knockout | Eye | Retina | 0.631387 | -0.663404 | 0.300020316696984 | 0.524683792062381 | DataSet_11_092 |
| Apoa1 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 10.2782 | 3.36152 | 0.0730938249724318 | 0.834975080343504 | DataSet_11_094 |
| Apoa1 | Sall1 | knockout | Kidney | Kidney | 2.71977 | 1.44349 | 0.00708491454761245 | 0.403273297534345 | DataSet_11_121 |
| Apoa1 | Sall1 | knockout | Kidney | Kidney | 0.221358 | -2.17555 | 0.289872687928105 | 0.948818235535782 | DataSet_11_122 |
| Apoa1 | Shox2 | knockout | Heart | Right atria | 0.554755 | -0.850078 | - | - | DataSet_11_124 |
| Apoa1 | Smad1 | knockout | Lung | Lung left lobe | 1.72538 | 0.786917 | 0.0439079557389585 | 0.542998753027287 | DataSet_11_126 |
| Apoa1 | Smad4 | siRNA | Brain | bEnd3 | 0.246043 | -2.02302 | - | - | DataSet_11_127 |
| Apoa1 | Smad4 | knockout | Aorta | Aortic arteries | 368.257 | 8.52457 | 0.0855230890564524 | 0.435181937381281 | DataSet_11_128 |
| Apoa1 | Snai1 | knockout | Embryo | Embryoid body | 0.571315 | -0.807643 | - | - | DataSet_11_129 |
| Apoa1 | Snai1 | knockout | Embryo | Teratoma | 0.367785 | -1.44307 | - | - | DataSet_11_130 |
| Apoa1 | Sohlh1 | knockout | Ovary | Ovary | 0.347118 | -1.5265 | 4.81799612937901e-09 | 1.36772492824142e-06 | DataSet_11_134 |
| Apoa1 | Sohlh2 | knockout | Ovary | Ovary | 0.356218 | -1.48917 | 3.01338898809563e-09 | 6.52600644050773e-07 | DataSet_11_135 |
| Apoa1 | Sox11 | knockout | Brain | Cortex | 0.579466 | -0.787203 | - | - | DataSet_11_138 |
| Apoa1 | Sox2 | shRNA | Embryo | ES cells | 2.09617 | 1.06775 | - | - | DataSet_11_140 |
| Apoa1 | Sox21 | knockout | Tooth | Incisor | 2.24045 | 1.16379 | - | - | DataSet_11_142 |
| Apoa1 | Spdef | knockout | Colon | Colon | 0.00282801 | -8.46599 | 0.0930456366319031 | 0.997507742354799 | DataSet_11_146 |
| Apoa1 | Stat3 | knockout | Lung | Lung typeII cells | 1.55018 | 0.632438 | 0.169963089190369 | 0.765546931892487 | DataSet_11_151 |
| Apoa1 | Stat6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 1.57999 | 0.659918 | 0.0809200578904773 | 0.213069359655496 | DataSet_11_153 |
| Apoa1 | Tet2 | knockout | Kidney | Kidney | 0.553439 | -0.853503 | 0.323808467707945 | 1 | DataSet_11_159 |
| Apoa1 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.511892 | -0.966088 | 0.147948041803687 | 0.999827445128963 | DataSet_11_174 |
| Apoa1 | Dnmt1 | siRNA | Pituitary_gland | AtT-20 | 1.50072 | 0.585657 | 2.988994e-01 | 0.9999923 | DataSet_11_187 |
| Apoa1 | Hipk2 | knockout | Heart | cardiac tissue | 1.97149 | 0.979288 | 2.187905e-01 | 5.324748e-01 | DataSet_11_238 |
| Apoa1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 0.507099 | -0.97966 | - | - | DataSet_11_196 |
| Apoa1 | Dnmt3a | knockout | Bone_marrow | Bone marrow-derived osteoclasts | 0.57277 | -0.803972 | - | - | DataSet_11_200 |
| Apoa1 | Dux | siRNA | Embryo | ES cells | 1.71429 | 0.777608 | 5.916941e-02 | 0.7961052086 | DataSet_11_239 |
| Apoa1 | Ncl | siRNA | Embryo | ES cells | 0.571429 | -0.807355 | 3.105951e-01 | 0.6196502073 | DataSet_11_240 |
| Apoa1 | Dnmt3a | siRNA | Embryo | iPSC | 0.180124 | -2.47294 | - | - | DataSet_11_241 |
| Apoa1 | Dnmt3b | siRNA | Embryo | iPSC | 0.500512 | -0.998524 | - | - | DataSet_11_242 |
| Apoa1 | Fubp1 | shRNA | Brain | brain neural progenitors | 0.455376 | -1.13487 | 0.5807274515 | 1 | DataSet_11_246 |
| Apoa1 | Dnmt1 | siRNA | Embryo | Embryo | 0.285714 | -1.80736 | - | - | DataSet_11_248 |
| Apoa1 | Kdm2a | CRISPR | Embryo | ES cells | 0.363636 | -1.45943 | 0.0362188657 | 1.0000000 | DataSet_11_251 |
| Apoa1 | Ctnnb1 | knockout | Embryo | MGE cells | 2.86526 | 1.51867 | 3.758584e-01 | 0.578475918 | DataSet_11_266 |
| Apoa1 | Nsd2 | knockout | Bone_marrow | Bone marrow immature B cells | 3.71615 | 1.89381 | 2.249531e-01 | 0.48206894 | DataSet_11_267 |
| Apoa1 | Dux | knockout | Embryo | Embryo | 896.324 | 9.80788 | 8.657758e-03 | 3.882143e-02 | DataSet_11_269 |
| Apoa1 | Mef2d | CRISPR | Heart | Cardiac ventricle | 1.64888 | 0.721488 | 4.436967e-01 | 0.6678073155 | DataSet_11_270 |
| Apoa1 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 7.75 | 2.9542 | 4.879486e-02 | 0.5927415 | DataSet_11_271 |
| Apoa1 | Dux | knockout | Embryo | Embryo | 896.324 | 9.80788 | 8.657740e-03 | 3.881756e-02 | DataSet_11_273 |
| Apoa1 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 2.2062 | 1.14157 | 3.833802e-01 | 5.598103e-01 | DataSet_11_275 |
| Apoa1 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 2 | 1 | 5.829601e-01 | 7.837272e-01 | DataSet_11_276 |
| Apoa1 | Gsk3b | CRISPR | Neuron | mPFC D2 neurons | 0.201862 | -2.30856 | 6.102846e-02 | 0.85266614 | DataSet_11_277 |
| Apoa1 | Ssrp1 | CRISPR | Embryo | ES cells | 0.181818 | -2.45943 | 7.153205e-03 | 0.5941229 | DataSet_11_278 |
| Apoa1 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 1.58018 | 0.660086 | 3.274762e-01 | 0.5472125 | DataSet_11_284 |
| Apoa1 | Usp7 | siRNA | Embryo | ES cells | 0.357143 | -1.48543 | 5.961345e-01 | 0.7686529 | DataSet_11_287 |
| Apoa1 | Kmt2d | CRISPR | Liver | MA1L | 0.519604 | -0.944516 | 4.859376e-01 | 7.059492e-01 | DataSet_11_290 |
| Apoa1 | Kmt2d | CRISPR | Liver | MA1L | 0.530565 | -0.914398 | 4.972377e-01 | 7.118033e-01 | DataSet_11_291 |
| Apoa1 | Tfap2a | knockout | Brain | Brain | 3 | 1.58496 | 0.0701548261 | 0.9599640 | DataSet_11_295 |
| Apoa1 | Ssrp1 | CRISPR | Embryo | ES cells | 5 | 2.32193 | 7.700018e-04 | 0.06601329 | DataSet_11_296 |
| Apoa1 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 13.9184 | 3.79892 | 7.294733e-02 | 5.591064e-01 | DataSet_11_297 |
| Apoa1 | Phf8 | knockout | prostate | Prostate | 31.75 | 4.98869 | 0.4160188837 | 0.6605876 | DataSet_11_298 |
| Apoa1 | Dnmt1 | knockout | Skin | Keratinocytes | 1.76342 | 0.818379 | 7.310074e-02 | 0.3792411242 | DataSet_11_303 |
| Apoa1 | Satb2 | CRISPR | Colon | Colon organoid | 4.40026 | 2.13759 | 4.450960e-03 | 0.4719791 | DataSet_11_304 |
| Apoa1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.555556 | -0.847997 | - | - | DataSet_11_305 |
| Apoa1 | Tbx20 | knockdown | Heart | primary cardiac fibroblasts | 0.333333 | -1.58496 | 3.184647e-01 | 0.84419466 | DataSet_11_309 |
| Apoa1 | Satb2 | knockout | Colon | Intestine epithelium | 162.27 | 7.34226 | 2.605729e-06 | 0.0014047041 | DataSet_11_316 |
| Apoa1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 2 | 1 | 4.588504e-01 | 0.7498467608 | DataSet_11_317 |
| Apoa1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.583211 | -0.777911 | 2.120817e-01 | 5.075944e-01 | DataSet_11_319 |
| Apoa1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.394161 | -1.34315 | 3.097364e-02 | 1.510165e-01 | DataSet_11_320 |
| Apoa1 | Bud31 | knockout | Testis | Spermatogonial stem cells | 0.619632 | -0.690517 | 6.930254e-01 | 0.9034252 | DataSet_11_321 |
| Apoa1 | Gata2 | knockout | Brain | Pituitary gland | 0.271739 | -1.87971 | 0.767452575 | 1.0000000 | DataSet_11_322 |
| Apoa1 | Padi2 | knockout | Testis | Testis | 4.75 | 2.24793 | 1.461424e-02 | 0.5838318 | DataSet_11_324 |
| Apoa1 | Snai1 | knockdown | Heart | Heart | 0.128847 | -2.95627 | 2.332914e-01 | 0.45451366 | DataSet_11_326 |
| Apoa1 | Dnmt3l | knockout | Testis | Spermatogonial progenitor cells | 3.44282 | 1.78359 | - | - | DataSet_11_328 |
| Apoa1 | Dnmt3a | knockout | Brain | Cortex | 0.475398 | -1.07279 | 2.535850e-03 | 0.6144431 | DataSet_11_330 |
| Apoa1 | Ezh2 | knockout | Eye | Retina | 1.6 | 0.678072 | 2.198503e-01 | 8.185078e-01 | DataSet_11_333 |
| Apoa1 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 10 | 3.32193 | 2.540872e-03 | 0.16377756 | DataSet_11_338 |
| Apoa1 | Gtf2ird1 | knockout | Lip | Lip | 1.66667 | 0.736966 | 2.001177e-01 | 6.345629e-01 | DataSet_11_339 |
| Apoa1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 6 | 2.58496 | 1.447685e-01 | 0.251330626 | DataSet_11_340 |
| Apoa1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 6.84772 | 2.77562 | 0.0414389857 | 0.1712697 | DataSet_11_341 |
| Apoa1 | Hnrnpk | siRNA | Embryo | ES cells | 0.386952 | -1.36977 | 1.559798e-02 | 0.037860722 | DataSet_11_342 |
| Apoa1 | Pcbp1 | shRNA | Thymus | Th1 | 3 | 1.58496 | 2.037844e-01 | 0.47636835 | DataSet_11_343 |
| Apoa1 | Dux | shRNA | Embryo | ES cells | 2.3 | 1.20163 | 1.890201e-01 | 6.644478e-01 | DataSet_11_345 |
| Apoa1 | Gata4 | CRISPR | Heart | primary cardiac fibroblasts | 0.333333 | -1.58496 | 3.184647e-01 | 0.84419466 | DataSet_11_347 |
Regulation Region
Expression Atlas of Apoa1