Gene Overview
Target Gene: CCNB3
NCBI Official Symbol: CCNB3
Entrez ID: 85417
Ensembl ID: ENSG00000147082
Gene Full Name: cyclin B3
Strand: +
Gene Locus: Xp11.22
External Links:

CCNB3 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CCNB3   
T(co)Fs that Repress CCNB3
The Intensity of the Gene Regulated by T(co)Fs:
CCNB3-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CCNB3 GATA2 siRNA Uterus Decidual stromal cells 0.656262 -0.607656 0.132021825740443 0.760171899646693 DataSet_03_100
CCNB3 HIC1 CRISPR Prostate PC3 0.290614 -1.78282 - - DataSet_03_118
CCNB3 MYC siRNA Colon HT29 1.71013 0.77411 - - DataSet_03_177
CCNB3 MYC siRNA Central_nervous_system DAOY M2.1 0.44023 -1.18367 3.43875932864907e-08 8.14730123215487e-07 DataSet_03_178
CCNB3 NR4A3 siRNA Pancreas 1.1B4 1.90129 0.926981 1.33153669455762e-06 3.71004421483595e-05 DataSet_03_203
CCNB3 PHB shRNA Embryo Embryonic stem cells (ESCs) 1.8795 0.910352 0.0500099630162816 0.113056242730721 DataSet_03_211
CCNB3 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.611111 -0.710493 - - DataSet_03_246
CCNB3 SP1 siRNA Ovary OVSAYO 0.601404 -0.733594 0.033894575439286 0.226986765123926 DataSet_03_251
CCNB3 STAT3 CRISPR Embryo hESC 9.9474 3.31432 0.0116195683904894 0.0679044895513323 DataSet_03_258
CCNB3 STAT6 siRNA Umbilical_vein HUVEC 0.662404 -0.594217 0.357446844441001 0.885849540833116 DataSet_03_264
CCNB3 TFAP2C siRNA Mammary_gland MCF7 2.04138 1.02955 0.0659297689494338 0.403524880755726 DataSet_03_274
CCNB3 TP63 siRNA Foreskin Neonatal foreskin keratinocytes 1.67198 0.741556 0.112319911110958 0.74068467747383 DataSet_03_282
CCNB3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.61905 0.695145 0.252556291706469 0.724428305565091 DataSet_04_001
CCNB3 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.0323044955377452 0.102506761338445 DataSet_04_002
CCNB3 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.326531 -1.61471 0.172486648753875 0.265295343319868 DataSet_04_004
CCNB3 CTCF CRISPR Haematopoietic_and_lymphoid_tissue K562 2.83333 1.5025 0.025168311609029 0.341279286606256 DataSet_04_005
CCNB3 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.6875 0.754888 0.518543789329091 0.779968138480805 DataSet_04_006
CCNB3 E4F1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.83333 1.5025 0.0505354729596784 0.48199053531887 DataSet_04_007
CCNB3 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.03704 1.02647 0.246971298571477 0.596882832732466 DataSet_04_008
CCNB3 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.8125 0.857981 0.120743362311244 0.790203892064082 DataSet_04_011
CCNB3 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 3.6 1.848 0.0153506588291009 0.0391271158371325 DataSet_04_012
CCNB3 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 90.5882 6.50125 0.172733800241054 0.307963069881825 DataSet_04_014
CCNB3 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.266667 -1.90689 0.0343574395800421 0.81150282769151 DataSet_04_016
CCNB3 RPS3 CRISPR Haematopoietic_and_lymphoid_tissue K562 5.11111 2.35364 0.0332463669595778 0.400849584985145 DataSet_04_017
CCNB3 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.92857 0.947533 0.151187331377152 0.289322674243576 DataSet_04_018
CCNB3 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.73913 0.798366 0.230698503130812 0.402442584799056 DataSet_04_019
CCNB3 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.326531 -1.61471 0.0508294269504696 0.257926393817317 DataSet_04_021
CCNB3 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.91304 1.54253 0.93425467620392 0.975972785200047 DataSet_04_022
CCNB3 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.0116125931556916 0.117392123079289 DataSet_04_023
CCNB3 ANXA2 CRISPR Liver HepG2 1.82609 0.868756 0.559113934910786 0.863791501680803 DataSet_04_024
CCNB3 APTX CRISPR Liver HepG2 2.5 1.32193 0.206747895729028 0.60769719465749 DataSet_04_025
CCNB3 E4F1 CRISPR Liver HepG2 0.294118 -1.76553 0.0821283984952056 0.351868181464487 DataSet_04_028
CCNB3 FUBP1 shRNA Liver HepG2 0.2 -2.32193 0.296358246353728 0.633744016565176 DataSet_04_030
CCNB3 MECP2 CRISPR Liver HepG2 0.3 -1.73697 0.475521699242279 0.70895732325406 DataSet_04_031
CCNB3 PAN2 CRISPR Liver HepG2 5.5 2.45943 0.0223009296141776 0.136536201187318 DataSet_04_033
CCNB3 SMAD2 CRISPR Liver HepG2 2.54839 1.34958 0.340072496262155 0.769486226436651 DataSet_04_034
CCNB3 SMAD4 CRISPR Liver HepG2 2.125 1.08746 0.0918404100950025 0.224559238252107 DataSet_04_035
CCNB3 SMAD5 CRISPR Liver HepG2 14.5 3.85798 0.264587597899806 0.646009017324315 DataSet_04_036
CCNB3 WRN shRNA Liver HepG2 0.5 -1 0.721588833406597 0.848329072672939 DataSet_04_038
CCNB3 ZNF574 CRISPR Liver HepG2 2.75 1.45943 0.0977841935753846 0.211613524822355 DataSet_04_041
CCNB3 DDX20 CRISPR Liver HepG2 0.3 -1.73697 0.475618917062826 0.61564351113589 DataSet_04_043
CCNB3 CHCHD3 CRISPR Liver HepG2 3 1.58496 0.491813776984194 0.772200676035276 DataSet_04_067
CCNB3 CNOT7 CRISPR Liver HepG2 0.419355 -1.25376 0.0425372585940549 0.118229771448688 DataSet_04_045
CCNB3 DNMT3B CRISPR Liver HepG2 2.17647 1.12199 0.361438874810858 0.628062988388941 DataSet_04_044
CCNB3 PAN2 CRISPR Liver HepG2 2.125 1.08746 0.278054893588899 0.455046175244299 DataSet_04_066
CCNB3 RIOK2 CRISPR Liver HepG2 0.285714 -1.80735 0.711411868609423 1 DataSet_04_070
CCNB3 ABT1 shRNA Liver HepG2 43 5.42626 0.22079663574241 0.340335274062224 DataSet_04_052
CCNB3 CALR shRNA Liver HepG2 0.657895 -0.604071 0.472785776166646 0.614164880852437 DataSet_04_053
CCNB3 CCAR1 shRNA Liver HepG2 0.625 -0.678072 0.805150677122585 0.894869296729374 DataSet_04_054
CCNB3 CNOT7 shRNA Liver HepG2 66 6.04439 0.0812080656253203 0.141085587434656 DataSet_04_051
CCNB3 NPM1 shRNA Liver HepG2 3.66667 1.87447 0.5006995313417 0.854822290395203 DataSet_04_058
CCNB3 PRPF6 shRNA Liver HepG2 4 2 0.650873581846587 0.816838483722115 DataSet_04_056
CCNB3 UBE2L3 shRNA Liver HepG2 0.0487805 -4.35755 0.15408550413244 0.276312921878288 DataSet_04_055
CCNB3 YBX3 shRNA Liver HepG2 1.66667 0.736966 0.869082794206246 0.936032277097885 DataSet_02_98
CCNB3 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.554824692329742 0.745217515993561 DataSet_04_048
CCNB3 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.16667 2.05889 0.223199192750366 0.72466483042355 DataSet_04_047
CCNB3 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.8125 0.857981 0.537637173923947 0.838774490582238 DataSet_04_050
CCNB3 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.25 1.16992 0.485384050806656 0.863548156968955 DataSet_04_076
CCNB3 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.363374805788365 1 DataSet_04_077
CCNB3 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.700778886106182 0.923058490273404 DataSet_04_073
CCNB3 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.5 2.16992 0.118452949569114 0.465489652831058 DataSet_04_075
CCNB3 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.16667 1.66297 0.26264494335882 0.422052899092249 DataSet_04_049
CCNB3 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.64706 0.719892 0.565162511106843 0.771883985720494 DataSet_02_38
CCNB3 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.176471 -2.5025 0.379732947608425 0.543326193770451 DataSet_02_14
CCNB3 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 2 1 0.420449766995862 0.598083171719814 DataSet_02_34
CCNB3 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.372461694533175 0.728376997294906 DataSet_02_75
CCNB3 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 9.14706 3.19331 0.30785154393128 0.564518189918575 DataSet_02_32
CCNB3 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.324675 -1.62293 0.452527544376682 0.807995878391235 DataSet_02_49
CCNB3 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.470588 -1.08746 0.615983757189639 0.777809568307939 DataSet_02_43
CCNB3 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5.23529 2.38827 0.276675158217066 0.426762629365892 DataSet_02_33
CCNB3 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.70588 0.770518 0.424084469285071 0.594078108054921 DataSet_02_53
CCNB3 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.433333 -1.20645 0.223201056854062 0.376075107482329 DataSet_04_060
CCNB3 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0588235 -4.08746 0.191060984460175 0.364762698188481 DataSet_04_064
CCNB3 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.231780988726435 0.42404875194352 DataSet_04_061
CCNB3 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.117647 -3.08746 0.248574757243259 0.68482782799379 DataSet_04_063
CCNB3 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.937927034978011 0.991541782545828 DataSet_04_065
CCNB3 SMARCA4 siRNA Colon HCT116 2.04932 1.03515 6.404986e-02 8.331280e-01 DataSet_03_301
CCNB3 SNAI2 shRNA Pancreas KLM1 0.318534 -1.65048 8.472923e-03 0.15969341 DataSet_03_307
CCNB3 ESR1 siRNA Mammary_gland MCF7 0.499471 -1.00153 1.700985e-01 0.3937665512 DataSet_03_352
CCNB3 TET1 CRISPR Mammary_gland Hs578T 0.0558361 -4.16266 3.030929e-01 5.012091e-01 DataSet_03_355
CCNB3 CREBBP CRISPR Brain U5-NPC 4 2 0.3845134914 0.7490853 DataSet_03_356
CCNB3 PTPN14 CRISPR Brain U5-NPC 0.5 -1 2.871935e-01 0.50665633 DataSet_03_357
CCNB3 TP53 CRISPR Brain U5-NPC 6 2.58496 3.363050e-02 1.683292e-01 DataSet_03_358
CCNB3 EP300 shRNA Mammary_gland MCF10AT 1.72727 0.788496 2.654087e-01 0.462324270 DataSet_03_364
CCNB3 ZNF148 shRNA Mammary_gland MDA-MB-231 1.87599 0.907653 1.132903e-03 0.029752703 DataSet_03_366
CCNB3 USP22 shRNA Liver PLC_PRF_5 cells 4.10195 2.03631 1.581019e-03 0.06724518 DataSet_03_368
CCNB3 ZFP36L1 siRNA Urinary_bladder J82 15 3.90689 - - DataSet_03_371
CCNB3 BHLHE40 shRNA Cervix HeLaS3 2.3125 1.20945 6.545215e-01 0.94392039 DataSet_03_372
CCNB3 E2F1 siRNA Nasopharynx HK1 0.470588 -1.08746 9.980024e-01 1.000000e+00 DataSet_03_373
CCNB3 HNRNPU siRNA Colon RKO 0.635741 -0.653489 - - DataSet_03_374
CCNB3 GLI1 siRNA Skeletal_muscle RMS13 2.81919 1.49528 1.404161e-03 0.024753795 DataSet_03_375
CCNB3 EZH2 CRISPR Ovary SKOV3 9.75 3.2854 7.936225e-02 0.2402589953 DataSet_03_378
CCNB3 ZBTB7A siRNA Stomach BGC823 1.62473 0.700198 - - DataSet_03_380
CCNB3 DNMT1 siRNA Skin Human melanoma cells 2.78561 1.478 1.575259e-03 4.563765e-03 DataSet_03_382
CCNB3 TCF19 CRISPR Oral_squamous CAL27 0.582537 -0.779579 2.646620e-01 0.5851206937 DataSet_03_383
CCNB3 YY1 shRNA Brain GSC1517 0.414284 -1.27131 - - DataSet_03_384
CCNB3 YY1 shRNA Brain GSC3028 2.66667 1.41504 - - DataSet_03_386
CCNB3 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 0.509181 -0.973749 0.4690694229 0.8806391 DataSet_03_387
CCNB3 NFKBIA shRNA Bone_marrow U2OS 0.42122 -1.24735 8.571125e-01 0.93958342 DataSet_03_389
CCNB3 YY1 knockdown Liver HepG2 0.291667 -1.77761 2.141012e-01 3.883719e-01 DataSet_03_390
CCNB3 KDM5A CRISPR Lung GLC16 3.54725 1.8267 4.972590e-01 0.652738926 DataSet_03_392
CCNB3 ASXL1 CRISPR Embryo iPSC 0.498465 -1.00444 0.1753657494 0.8187866 DataSet_03_394
CCNB3 IKZF2 CRISPR Lymph CAR T Cell 0.380482 -1.3941 3.430861e-01 0.760551048 DataSet_03_397
CCNB3 TLE4 CRISPR Lymph CAR T Cell 1.60802 0.685288 6.652746e-01 0.87329899 DataSet_03_398
CCNB3 HMGA1 shRNA Bile_duct HUCCT1 0.5 -1 4.579621e-01 0.664532869 DataSet_03_400
CCNB3 TFAP2A knockout Embryo H9 1.59459 0.67319 2.464733e-01 0.40531584 DataSet_03_405
CCNB3 STRAP knockout Nerve SK-N-AS 2.54688 1.34873 - - DataSet_03_409
CCNB3 USP22 shRNA Liver HuH7 6.45604 2.69065 - - DataSet_03_411
CCNB3 E2F6 shRNA Liver HuH7 0.621716 -0.685672 - - DataSet_03_412
CCNB3 RUNX2 shRNA Cord_blood Natural Killer Cell 1.71429 0.777608 5.511202e-01 0.842974826 DataSet_03_416
CCNB3 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 1.65217 0.724366 1.518937e-01 0.333468746 DataSet_03_418
CCNB3 FOXK2 shRNA Ovary OVCAR-5 0.649123 -0.623437 3.317217e-01 0.45139695 DataSet_03_419
CCNB3 PRDM1 CRISPR Lymph CD8+ T cells 0.627551 -0.672195 - - DataSet_03_421
CCNB3 MAEL CRISPR Liver Alexander cells 2.47458 1.30718 - - DataSet_03_423
CCNB3 FOXP3 CRISPR Peripheral_blood Naive Treg 2.06452 1.0458 5.052348e-02 0.315360869 DataSet_03_427
CCNB3 IKZF2 shRNA Lymph Hut78 1.68633 0.753883 2.534578e-01 0.73609286 DataSet_03_429
CCNB3 USP7 shRNA Skin xenograft cells 0.468599 -1.09357 0.25928047 0.4348960 DataSet_03_431
CCNB3 POU2AF1 CRISPR Lymph SUDHL4 0.5 -1 6.665080e-01 0.749951902 DataSet_03_435
CCNB3 EP300 knockout Pancreas HPAF-II orthotopic cells 1.58207 0.661817 6.114022e-02 1.639234e-01 DataSet_03_436
CCNB3 SETDB1 shRNA Colon HCT116 0.570651 -0.809319 - - DataSet_03_440
CCNB3 FOSL1 siRNA Prostate MSKPCa3 0.5 -1 0.1757345299 0.5297688 DataSet_03_445
CCNB3 RELB CRISPR Colon SW480 3.31034 1.72698 1.388249e-03 2.660576e-02 DataSet_03_449
CCNB3 OGT siRNA Embryo BeWo cells 1.71429 0.777608 2.189588e-01 0.66237450 DataSet_03_453
CCNB3 SMARCA2 shRNA Lung HCC2302 1.97345 0.980718 5.685070e-06 1.274749e-05 DataSet_03_455
CCNB3 PPARG siRNA Aortic_valve Valvular endothelial cell 0.429412 -1.21957 1.912146e-02 1.970496e-01 DataSet_03_456
CCNB3 ARID1A shRNA Bile_duct MMNK1 9.48594 3.24579 2.002505e-04 0.013946232 DataSet_03_458
CCNB3 PARP1 knockout Embryo_kidney HEK293a 1.53636 0.61952 8.158268e-03 2.681626e-02 DataSet_03_464
CCNB3 STAT3 shRNA Liver HepG2 2.53488 1.34192 2.472548e-02 0.2481042569 DataSet_03_465
CCNB3 SMARCA1 Cas13 Embryo_kidney HEK293T 0.378788 -1.40054 - - DataSet_03_466
CCNB3 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 1.99242 0.994525 - - DataSet_03_467
CCNB3 SMARCA1 shRNA Embryo_kidney HEK293T 0.545455 -0.874469 - - DataSet_03_468
CCNB3 WHSC1 siRNA Prostate PC3 6.875 2.78136 2.233424e-02 0.14553771 DataSet_03_471
CCNB3 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 1.61905 0.695145 0.3446474 0.7712966 DataSet_04_072
CCNB3 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 4 2 0.155045 0.286075454 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate SMAD5 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CCNB3
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines