Gene Overview
Target Gene: EREG
NCBI Official Symbol: EREG
Entrez ID: 2069
Ensembl ID: ENSG00000124882
Gene Full Name: epiregulin
Strand: +
Gene Locus: 4q13.3
External Links:

EREG Significantly Regulated by These T(co)Fs

T(co)Fs that Activate EREG   
T(co)Fs that Repress EREG
The Intensity of the Gene Regulated by T(co)Fs:
EREG-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
EREG IRF2 shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 1.80998 0.85598 0.03505 0.25296 DataSet_01_100
EREG MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 2.26917 1.18216 1.37537e-05 9.92556e-05 DataSet_01_102
EREG SPDEF shRNA Mammary_gland MCF7 0.20862 -2.26105 0.32487 0.99999 DataSet_01_107
EREG HOXA1 siRNA Lung_fibroblast IMR-90 11.9544 3.57947 7.97453e-06 0.00544 DataSet_01_110
EREG GABPA siRNA Lung A549 0.6546 -0.61131 9.92895e-08 1.93166e-06 DataSet_01_113
EREG ID1 siRNA Lung H1650 1.99828 0.99876 0.00958 0.32206 DataSet_01_118
EREG ZIC2 siRNA Pancreas PANC1 0.36615 -1.4495 - - DataSet_01_121
EREG FOXM1 siRNA Central_nervous_system U87 24.083 4.58994 - - DataSet_01_122
EREG TEAD4 shRNA Stomach SNU216 1.53046 0.61396 - - DataSet_01_151
EREG HSF1 shRNA Skin A375 2.08529 1.06025 6.90398e-05 0.00174 DataSet_01_155
EREG ELK1 siRNA Peripheral_blood CD4+ T cells 0.45064 -1.14996 0.17563 0.36199 DataSet_01_162
EREG GATA3 siRNA Peripheral_blood CD4+ T cells 0.23391 -2.09595 0.00982 0.1881 DataSet_01_163
EREG JUN siRNA Peripheral_blood CD4+ T cells 0.57635 -0.79499 0.44189 0.68714 DataSet_01_164
EREG MAF siRNA Peripheral_blood CD4+ T cells 0.46663 -1.09965 0.20775 0.55182 DataSet_01_165
EREG NFKB1 siRNA Peripheral_blood CD4+ T cells 0.2571 -1.95958 0.01512 0.34686 DataSet_01_167
EREG TP53 siRNA Lung SAECs 0.48036 -1.0578 0.00048 0.11835 DataSet_01_175
EREG CREB1 shRNA Parotid_gland H3118 MEC 2.95739 1.56433 0.80172 0.92748 DataSet_01_194
EREG CREB1 shRNA Parotid_gland HSY 0.52848 -0.92008 0.04185 0.5517 DataSet_01_195
EREG TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.81493 0.85991 - - DataSet_01_196
EREG TP63 siRNA Head_and_neck SCC-012 0.65112 -0.61902 - - DataSet_01_201
EREG TP63 siRNA Head_and_neck SCC-6 0.56265 -0.82968 - - DataSet_01_202
EREG XBP1 shRNA Mammary_gland T47D 3.57901 1.83956 5.26055e-06 0.00029 DataSet_01_203
EREG FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.64366 -0.63564 - - DataSet_01_209
EREG FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.50563 -0.98386 - - DataSet_01_210
EREG REST siRNA Prostate LNCaP 0.6489 -0.62394 0.03309 0.22988 DataSet_01_211
EREG TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 2.33977 1.22636 0.00298 0.0253 DataSet_01_217
EREG KLF2 shRNA Bone_marrow RPMI8226 0.53347 -0.90653 0.02945 0.55876 DataSet_01_226
EREG IRX1 shRNA Bone_marrow 143B 2.80717 1.48912 0.07463 0.28094 DataSet_01_227
EREG ZEB1 siRNA Cervix HeLa229 1.83387 0.87489 - - DataSet_01_232
EREG STAT5 shRNA Haematopoietic_and_lymphoid_tissue K562 0.39077 -1.3556 2.81599e-05 0.00078 DataSet_01_239
EREG TWIST1 shRNA Stomach CAF32 4.72946 2.24167 6.09808e-05 0.012 DataSet_01_253
EREG TWIST1 shRNA Stomach CAF 1.91331 0.93607 0.35907 0.77461 DataSet_01_254
EREG YBX1 shRNA Mammary_gland MDA 2.54864 1.34973 1.57799e-05 6e-04 DataSet_01_257
EREG SOX4 shRNA Mammary_gland MDA-MB-231 1.59499 0.67354 0.04651 0.262 DataSet_01_260
EREG STAT5 shRNA Prostate CWR22Pc 0.50584 -0.98324 0.01654 0.07307 DataSet_01_279
EREG ESRRA shRNA Embryo_kidney 293T 0.62961 -0.66746 0.04137 0.64526 DataSet_01_280
EREG MSX1 siRNA Tooth Dental Pulp Cells 2.46015 1.29875 0.01724 0.04588 DataSet_01_281
EREG AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 0.30772 -1.70033 2.41323e-06 0.00014 DataSet_01_283
EREG SP3 siRNA Haematopoietic_and_lymphoid_tissue JURKAT 7.75519 2.95516 0.01446 0.77909 DataSet_01_290
EREG TFAP4 siRNA Brain BE(2)-C 0.23184 -2.10878 0.39903 0.51625 DataSet_01_295
EREG PTEN shRNA Skin A431 0.50758 -0.97828 0.04255 0.16856 DataSet_01_301
EREG ARNT siRNA Upper_aerodigestive_tract HSC3 0.38175 -1.3893 - - DataSet_01_315
EREG ELK3 shRNA Mammary_gland MDA-MB-231 0.23168 -2.1098 6.93463e-05 0.00046 DataSet_01_318
EREG MYC siRNA Colon HCT116 1.59276 0.67153 0.02483 0.04458 DataSet_01_324
EREG HOXC6 siRNA Prostate LNCaP 0.36615 -1.44948 0.11847 0.99927 DataSet_01_333
EREG GRHL3 siRNA Skin NHEK 0.54994 -0.86266 0.2759 0.73063 DataSet_01_336
EREG KLF7 siRNA Embryo HCE 0.19333 -2.37089 0.04265 0.6419 DataSet_01_340
EREG GATA3 siRNA Oral_cavity OEC-M1 0.65199 -0.61708 0.25819 0.99787 DataSet_01_347
EREG SMAD3 siRNA Pancreas BxPC-3 0.66596 -0.5865 - - DataSet_01_352
EREG ETV4 shRNA Prostate PC3 0.5484 -0.86669 - - DataSet_01_356
EREG RBFOX2 shRNA Liver HepG2 1.57143 0.65208 0.19813 0.66758 DataSet_02_101
EREG FIP1L1 shRNA Liver HepG2 5.13333 2.3599 0.00173 0.01819 DataSet_02_103
EREG HDGF shRNA Liver HepG2 3.33333 1.73697 0.0186 0.11269 DataSet_02_104
EREG ZNF622 shRNA Liver HepG2 0.18519 -2.43296 0.38348 0.46159 DataSet_02_108
EREG HNRNPUL1 shRNA Liver HepG2 0.48148 -1.05445 0.04922 0.10505 DataSet_02_109
EREG GTF2F1 shRNA Liver HepG2 1.60274 0.68054 0.03011 0.27476 DataSet_02_110
EREG BCLAF1 shRNA Liver HepG2 0.50617 -0.9823 0.00635 0.04003 DataSet_02_112
EREG XRCC5 shRNA Liver HepG2 3.67123 1.87626 0.00081 0.12055 DataSet_02_114
EREG PCBP1 shRNA Liver HepG2 8.25 3.04439 0.07288 0.12289 DataSet_02_115
EREG TARDBP shRNA Liver HepG2 0.56522 -0.82312 0.10525 0.1765 DataSet_02_116
EREG SUB1 shRNA Liver HepG2 2.72603 1.4468 0.00231 0.12645 DataSet_02_117
EREG RBM25 shRNA Liver HepG2 4.75 2.24793 0.04294 0.09505 DataSet_02_119
EREG PTBP1 shRNA Liver HepG2 39.75 5.31288 0.00078 0.00664 DataSet_02_120
EREG RBM34 shRNA Liver HepG2 0.60274 -0.73039 0.0139 0.39494 DataSet_02_121
EREG EWSR1 shRNA Liver HepG2 5.66667 2.5025 0.07661 0.1696 DataSet_02_122
EREG FUS shRNA Liver HepG2 1.69863 0.76437 0.00803 0.08333 DataSet_02_124
EREG HNRNPLL shRNA Liver HepG2 0.63043 -0.66558 0.35071 0.43516 DataSet_02_125
EREG SNRNP70 shRNA Liver HepG2 0.13043 -2.9386 0.03069 0.09054 DataSet_02_126
EREG SRSF3 shRNA Liver HepG2 3.91304 1.96829 0.01094 0.08555 DataSet_02_127
EREG TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 0.35258 -1.50396 0.01562 0.27212 DataSet_02_129
EREG RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.37288 -1.42321 0.02157 0.45812 DataSet_02_139
EREG BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65278 -0.61534 0.01853 0.1291 DataSet_02_142
EREG FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.04442 0.14678 DataSet_02_147
EREG NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.46945 -1.09095 0.0268 0.20524 DataSet_02_149
EREG SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56495 -0.82379 0.01065 0.42628 DataSet_02_150
EREG ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.33123 -1.59409 0.00862 0.24113 DataSet_02_152
EREG U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.49212 -1.02292 0.00964 0.0614 DataSet_02_170
EREG LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 1.60274 0.68054 0.41905 1 DataSet_02_175
EREG CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 2.15584 1.10825 0.33357 1 DataSet_02_176
EREG TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.6 -0.73697 0.16947 1 DataSet_02_178
EREG CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 0.625 -0.67807 0.77331 1 DataSet_02_185
EREG BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.68831 0.75558 0.42729 1 DataSet_02_188
EREG MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 1.63636 0.71049 0.45563 1 DataSet_02_189
EREG LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.63014 0.70499 0.35133 1 DataSet_02_191
EREG MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.84416 0.88296 0.28821 1 DataSet_02_192
EREG ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 1.53 0.61353 0.50077 1 DataSet_02_193
EREG TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.47945 1.31002 0.14683 1 DataSet_02_194
EREG LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.01299 1.00934 0.19522 1 DataSet_02_195
EREG CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.74026 0.7993 0.61012 1 DataSet_02_197
EREG TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.64706 0.71989 0.43188 1 DataSet_02_201
EREG BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.59211 0.67094 0.73612 1 DataSet_02_202
EREG RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.73864 0.79796 0.20575 1 DataSet_02_204
EREG E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 1.63636 0.71049 0.41144 1 DataSet_02_205
EREG AR siRNA Prostate abl cells 1.73457 0.794576 0.453649182784056 0.999852161656754 DataSet_03_004
EREG ASCL1 siRNA Lung DMS79 0.622263 -0.684404 0.454363828375934 0.904584974080861 DataSet_03_016
EREG BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.606127 -0.722307 0.48723806794507 0.909193184014261 DataSet_03_025
EREG BCL6 siRNA Lymph Pfeiffer DLBCL 1.60168 0.679589 0.147576269324141 0.624689647283837 DataSet_03_026
EREG CASP8AP2 siRNA Bone_marrow U2OS 2.59122 1.37363 3.6655903900883e-05 0.00215019364052705 DataSet_03_031
EREG CEBPB siRNA Embryo hESC 0.0348382 -4.84318 0.000975012253547722 0.115701652365275 DataSet_03_049
EREG E2F1 siRNA Cervix HeLa 0.613709 -0.704374 0.0125578442628588 0.994339149117477 DataSet_03_060
EREG ESR1 siRNA Uterus Endometrial stromal cells 1.7863 0.83697 - - DataSet_03_069
EREG FOXM1 siRNA Mammary_gland BT-20 cells 1.87097 0.903785 0.000929498642051878 0.113236397674437 DataSet_03_091
EREG FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.311007 -1.68498 - - DataSet_03_096
EREG GATA2 siRNA Uterus Decidual stromal cells 0.258044 -1.95431 0.726104043304005 0.974130551149242 DataSet_03_100
EREG GATA4 siRNA Stomach YCC3 1.74976 0.807153 0.277115622181338 0.778029145382714 DataSet_03_107
EREG GRHL3 siRNA Skin Primary neonatal keratinocytes 0.652855 -0.615166 0.0724336128509929 0.321157883773305 DataSet_03_113
EREG HIC1 CRISPR Prostate PC3 0.470623 -1.08736 - - DataSet_03_118
EREG HINFP siRNA Bone_marrow U2OS 2.65897 1.41087 3.35779028295652e-06 0.00258184082713571 DataSet_03_123
EREG HNF4a siRNA Liver HepG2 1.84915 0.886866 0.0505863059690267 0.638880897985671 DataSet_03_126
EREG IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 4.17747 2.06263 0.13424386463144 0.998575942529912 DataSet_03_134
EREG JUN siRNA Fibroblasts WI38 0.479395 -1.06071 0.00086359816817983 0.0139891458275314 DataSet_03_140
EREG JUN siRNA Fibroblasts WI38 0.479395 -1.06071 0.000862789397274815 0.0138911014541195 DataSet_03_141
EREG Klf4 siRNA Skin Primary neonatal keratinocytes 0.253181 -1.98176 2.25709394713896e-05 0.00099795444235607 DataSet_03_147
EREG MEF2D shRNA Liver HuH7 2.8965 1.53431 - - DataSet_03_162
EREG MEF2D siRNA Liver HuH7 3.46014 1.79083 - - DataSet_03_163
EREG MTA2 siRNA Stomach SGC-7901 2.65452 1.40845 - - DataSet_03_169
EREG MYB siRNA Cord_Blood CD34+ progenitor cells 2.04759 1.03393 - - DataSet_03_170
EREG NPAT siRNA Bone_marrow U2OS 1.93593 0.953025 7.39291990927319e-05 0.00702734690504055 DataSet_03_201
EREG PHB shRNA Embryo Embryonic stem cells (ESCs) 2.57392 1.36397 0.0258149963108825 0.0667491038939894 DataSet_03_211
EREG RELA siRNA Fibroblasts WI38 1.65017 0.722619 0.00138124355509446 0.00958867765023479 DataSet_03_223
EREG RELB siRNA Immortalized_keratinocyte HaCaT 7.12458 2.8328 9.32063729875525e-07 2.71933129689316e-05 DataSet_03_227
EREG SOX11 siRNA Lung_fibroblast NHLF 0.665792 -0.586856 0.697094269731294 0.901527102406449 DataSet_03_238
EREG SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.03 -5.05889 - - DataSet_03_246
EREG SOX4 siRNA Mammary_gland MDA-LM2 0.424972 -1.23456 0.000989114461831177 0.181690107445265 DataSet_03_247
EREG SP1 siRNA Ovary OVSAYO 0.347312 -1.52569 0.0213573606246066 0.184912983329836 DataSet_03_251
EREG STAT3 CRISPR Embryo hESC 0.342435 -1.5461 0.637928278462005 0.695997380493628 DataSet_03_258
EREG TET2 siRNA Prostate DU145 0.655787 -0.6087 - - DataSet_03_271
EREG TFAP2C siRNA Mammary_gland MCF7 1.84242 0.881602 0.0903587497463455 0.435350355110232 DataSet_03_274
EREG TFE3 siRNA Kidney UOK257-2 0.608928 -0.715656 - - DataSet_03_275
EREG TP53 siRNA Foreskin Neonatal foreskin keratinocytes 0.575855 -0.796222 0.123142831895744 0.999791649573014 DataSet_03_278
EREG TP63 siRNA Skin Primary neonatal keratinocytes 0.530673 -0.914106 0.0148449176141736 0.0638210623257749 DataSet_03_281
EREG TP63 siRNA Foreskin Neonatal foreskin keratinocytes 0.575217 -0.797821 0.101829846895742 0.737723716449684 DataSet_03_282
EREG ZNF165 siRNA Mammary_gland SUM159 2.00913 1.00657 0.68197439068194 0.999998167536832 DataSet_03_288
EREG ZNF746 siRNA Colon HCT116 0.633317 -0.659 - - DataSet_03_293
EREG CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.595588 -0.747613 0.053478550664502 0.113031576133669 DataSet_04_004
EREG FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.546448 -0.871844 0.0786714323081284 0.172831540542629 DataSet_04_010
EREG MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.574661 -0.799218 0.0991201233788164 0.153319537054009 DataSet_04_012
EREG NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 460.115 8.84585 0.00206155765225151 0.01919254137629 DataSet_04_014
EREG NUP35 shRNA Haematopoietic_and_lymphoid_tissue K562 0.312217 -1.67938 0.026202350643836 0.0598705502823861 DataSet_04_015
EREG SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71642 0.779401 0.00298621706077529 0.0979887211869635 DataSet_04_019
EREG YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.853210827415389 0.943499902544234 DataSet_04_022
EREG CIZ1 CRISPR Liver HepG2 3.3 1.72247 0.0834741289658773 0.301279662185077 DataSet_04_026
EREG NFX1 CRISPR Liver HepG2 3.52308 1.81684 0.0168059632954344 0.0495131301478127 DataSet_04_032
EREG SMAD2 CRISPR Liver HepG2 1.78289 0.834221 0.000604115102709017 0.254405684313552 DataSet_04_034
EREG SRPK2 CRISPR Liver HepG2 1.66667 0.736966 0.0282350643660594 0.162743773776593 DataSet_04_037
EREG YBX1 CRISPR Liver HepG2 0.0257353 -5.28011 0.112512837269621 0.972884761036538 DataSet_04_039
EREG ZC3H8 shRNA Liver HepG2 0.107692 -3.21501 0.00844465958138156 0.097940630823289 DataSet_04_040
EREG DDX20 CRISPR Liver HepG2 2.2963 1.19931 0.0134644959520809 0.0766755541991372 DataSet_04_043
EREG CNOT7 CRISPR Liver HepG2 0.128289 -2.96253 4.76672265605103e-06 0.00817949022430367 DataSet_04_045
EREG DNMT3B CRISPR Liver HepG2 2.40909 1.26849 0.00692638473257088 0.0972198721320306 DataSet_04_044
EREG ABT1 shRNA Liver HepG2 0.2 -2.32193 0.05519389344904 0.119603355177899 DataSet_04_052
EREG CALR shRNA Liver HepG2 4.80702 2.26514 0.00142783962431118 0.0120899640828479 DataSet_04_053
EREG CNOT7 shRNA Liver HepG2 0.124224 -3.00899 0.000230541234230611 0.00361073106242933 DataSet_04_051
EREG DDX1 shRNA Liver HepG2 1.53086 0.614346 0.125668296224461 0.33389986077515 DataSet_04_057
EREG NPM1 shRNA Liver HepG2 1.7619 0.817136 0.450164040128324 0.824140935938555 DataSet_04_058
EREG UBE2L3 shRNA Liver HepG2 2.9375 1.55459 0.00277666303586674 0.018907113063201 DataSet_04_055
EREG YBX3 shRNA Liver HepG2 0.654321 -0.61193 0.172236219641454 0.347430103609352 DataSet_02_98
EREG NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.64925 0.721813 0.00331045953168662 0.0486277423162384 DataSet_04_046
EREG DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.615385 -0.70044 0.675721344581137 0.808270250308301 DataSet_02_14
EREG SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.53846 1.34395 0.142972734015723 0.265023629079052 DataSet_02_47
EREG SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.875 0.906891 0.702028171743191 0.938524266673806 DataSet_02_49
EREG TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.46154 1.29956 0.188939778069343 0.319490452520193 DataSet_02_33
EREG ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.319672 -1.64534 0.00166955931071975 0.0256397641909137 DataSet_04_060
EREG CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.337539 -1.56687 0.0106494664686839 0.0820505867825643 DataSet_04_061
EREG DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.393162 -1.3468 0.00560113722749897 0.387576621454989 DataSet_04_063
EREG PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 1.65714 0.728698 0.209456528127166 0.584762382292707 DataSet_04_065
EREG UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.592105 -0.756074 0.0371876823067862 0.184701346745722 DataSet_04_062
EREG CNOT3 shRNA Lung A549 1.94776 0.961813 2.813698e-01 0.8887602 DataSet_03_340
EREG EZH2 shRNA Colon SW480 2.79097 1.48076 - - DataSet_03_298
EREG AEBP1 siRNA Umbilical_vein HUVEC 1.6514 0.723693 6.359853e-02 0.563238092 DataSet_03_300
EREG SMARCA4 siRNA Colon HCT116 2.90948 1.54076 3.138231e-03 1.626728e-01 DataSet_03_301
EREG SMARCA4 siRNA Colon HCT116 1.57852 0.658568 3.279910e-02 0.1880765 DataSet_03_302
EREG PRMT1 shRNA Lung A549 0.463625 -1.10897 - - DataSet_03_342
EREG ACTR5 siRNA Muscle RD 1.69061 0.757542 - - DataSet_03_343
EREG BRCA1 siRNA Mammary_gland MCF7 1.6991 0.764773 3.438753e-01 0.9999931 DataSet_03_308
EREG EZH2 knockdown Colon HCT116 1.50143 0.58634 0.210367953 0.8827142 DataSet_03_334
EREG ARID3B CRISPR Colon HCT15 2.28756 1.19381 - - DataSet_03_335
EREG TET1 CRISPR Mammary_gland MDA-MB-231 0.129505 -2.94892 5.656006e-06 3.797065e-04 DataSet_03_347
EREG ESR1 siRNA Mammary_gland MCF7 1.77471 0.827582 2.250330e-01 0.4735142714 DataSet_03_352
EREG ETV5 knockdown Colon HT29 2.03835 1.0274 1.772691e-01 0.460918087 DataSet_03_353
EREG TET1 CRISPR Mammary_gland Hs578T 1.56255 0.643899 6.640265e-01 8.088290e-01 DataSet_03_355
EREG NCOA2 siRNA Uterus endometrial stromal cells 0.657205 -0.605584 0.8192929407 1 DataSet_03_360
EREG EP300 shRNA Mammary_gland MCF10AT 1.81818 0.862496 1.059312e-01 0.290972330 DataSet_03_364
EREG TP53 knockout Stomach SNU1 1.74195 0.800706 0.2413684367 0.9301241 DataSet_03_365
EREG ZNF148 shRNA Mammary_gland MDA-MB-231 1.97936 0.985033 5.555158e-03 0.054870143 DataSet_03_366
EREG ABL1 shRNA Liver HuH7 4.37458 2.12914 9.383393e-05 0.0015697411 DataSet_03_367
EREG TPR shRNA Bone_marrow U2OS 1.81769 0.862109 2.096932e-01 6.425213e-01 DataSet_03_370
EREG ZFP36L1 siRNA Urinary_bladder J82 2.16872 1.11685 - - DataSet_03_371
EREG GLI1 siRNA Skeletal_muscle RMS13 3.829 1.93697 2.157370e-01 0.442298713 DataSet_03_375
EREG EZH2 CRISPR Ovary SKOV3 69.5 6.11894 4.030520e-05 0.0033887495 DataSet_03_378
EREG NFKB2 siRNA Bone_marrow U2OS 1.73485 0.79481 1.077891e-01 0.38841843 DataSet_03_381
EREG YY1 shRNA Brain GSC1517 1.75 0.807355 - - DataSet_03_384
EREG YY1 shRNA Brain GSC23 2 1 - - DataSet_03_385
EREG KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 1.67177 0.741373 0.4945094701 0.8873980 DataSet_03_387
EREG TRIM8 siRNA Mammary_gland MCF7 6.1 2.60881 2.946800e-03 0.0239582029 DataSet_03_388
EREG NFKBIA shRNA Bone_marrow U2OS 0.496456 -1.01026 6.170665e-01 0.87005461 DataSet_03_389
EREG YY1 knockdown Liver HepG2 14.5147 3.85944 8.139088e-10 3.546694e-08 DataSet_03_390
EREG KDM5A CRISPR Lung GLC16 4.57812 2.19476 6.419267e-01 0.775227158 DataSet_03_392
EREG ILF2 siRNA Stomach SGC-7901 1.69231 0.758992 0.1692916182 0.35083099 DataSet_03_393
EREG ASXL1 CRISPR Embryo iPSC 2.33682 1.22455 0.6627521093 0.9186084 DataSet_03_394
EREG JAZF1 siRNA Cervix HeLa Kyoto 1.82999 0.871833 6.981972e-02 0.703574669 DataSet_03_396
EREG TLE4 CRISPR Lymph CAR T Cell 0.528304 -0.92056 1.342768e-01 0.42342861 DataSet_03_398
EREG RELA CRISPR Brain T30 3.33207 1.73642 0.2453394215 0.8400824 DataSet_03_399
EREG HMGA1 shRNA Bile_duct HUCCT1 7.8541 2.97345 4.911326e-05 0.009697774 DataSet_03_400
EREG SUMO1 CRISPR Bone_marrow U2OS 0.628571 -0.669851 3.667258e-02 1.218030e-01 DataSet_03_401
EREG EHF shRNA Stomach MKN7 377.851 8.56168 - - DataSet_03_402
EREG JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.86957 0.902703 2.624451e-01 0.4685534 DataSet_03_403
EREG CHD1 shRNA Prostate LNCaP 0.0133945 -6.22222 1.101005e-01 6.313249e-01 DataSet_03_407
EREG MAP3K7 shRNA Prostate LNCaP 0.00875157 -6.83624 1.022363e-01 3.058425e-01 DataSet_03_408
EREG STRAP knockout Nerve SK-N-AS 4.39355 2.13539 - - DataSet_03_409
EREG SIRT1 siRNA Pancreas PANC1 0.422633 -1.24252 3.762974e-05 0.008076714 DataSet_03_410
EREG ZKSCAN3 CRISPR Colon HCT116 0.543121 -0.880654 8.637245e-02 0.457680117 DataSet_03_415
EREG MAEL CRISPR Liver Alexander cells 0.136226 -2.87593 - - DataSet_03_423
EREG STAT5B CRISPR Embryo_kidney HEK293 0.5 -1 2.009529e-01 0.665084591 DataSet_03_424
EREG FOXP3 CRISPR Peripheral_blood Naive Treg 2 1 3.737846e-01 0.688886184 DataSet_03_427
EREG STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 6.0053 2.58624 0.1755970793 1 DataSet_03_430
EREG USP7 shRNA Skin xenograft cells 0.642157 -0.639002 0.53323079 0.6622310 DataSet_03_431
EREG PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.514389 -0.95907 - - DataSet_03_432
EREG POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.98297 0.987664 1.378316e-02 0.348222411 DataSet_03_434
EREG SUFU shRNA Mammary_gland HCC1954 cells 0.155844 -2.68182 0.1177399752 0.6455297 DataSet_03_437
EREG CIC knockout Brain Immortalized Astrocyte Cells 2.76697 1.46831 2.731339e-01 7.215296e-01 DataSet_03_438
EREG FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.6 -0.736966 4.507190e-01 0.92867703 DataSet_03_439
EREG SETDB1 shRNA Colon HCT116 0.609447 -0.714427 - - DataSet_03_440
EREG DAXX shRNA Mammary_gland MDA-MB-231 2.32985 1.22024 1.375003e-03 0.05546830 DataSet_03_441
EREG PURA siRNA Cervix HeLa 3.16667 1.66297 1.105627e-03 0.047027228 DataSet_03_444
EREG FOSL1 siRNA Prostate MSKPCa3 0.615186 -0.700905 0.0148398498 0.3170955 DataSet_03_445
EREG RELB CRISPR Colon SW480 0.428571 -1.22239 3.308289e-01 5.110708e-01 DataSet_03_449
EREG CBX2 siRNA Mammary_gland MCF7 3.31089 1.72722 1.078140e-02 0.0321847883 DataSet_03_451
EREG SMARCA2 shRNA Lung HCC2302 25.1676 4.65349 5.962066e-10 3.797275e-09 DataSet_03_455
EREG IRF2 shRNA Cord_Blood CD34+ cells 2.81006 1.4906 - - DataSet_03_460
EREG TXNIP shRNA Cord_Blood CD34+ cells 3.24803 1.69957 - - DataSet_03_461
EREG TXNIP shRNA Cord_blood ST3 4.58654 2.19741 5.624987e-03 0.1204381817 DataSet_03_462
EREG PARP1 knockout Embryo_kidney HEK293a 3.95455 1.98351 4.470309e-04 2.365345e-03 DataSet_03_464
EREG STAT3 shRNA Liver HepG2 0.3125 -1.67807 9.407718e-03 0.1426810999 DataSet_03_465
EREG CREBBP CRISPR Lymph U2932 4.33333 2.11548 8.062952e-02 1.0000000 DataSet_03_474
EREG EZH2 siRNA Prostate LNCaP 2.5 1.32193 7.112131e-01 1.0000000 DataSet_03_475
Regulation Region
 
T(co)Fs that significantly regulate YBX1 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of EREG
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines