Gene Overview
Target Gene: Fosb
NCBI Official Symbol: Fosb
Entrez ID: 14282
Ensembl ID: ENSMUSG00000003545
Gene Full Name: FBJ osteosarcoma oncogene B
Strand: -
Gene Locus: 7 A3|7 9.56 cM
External Links:

Fosb Significantly Regulated by These T(co)Fs

T(co)Fs that Activate Fosb   
T(co)Fs that Repress Fosb
The Intensity of the Gene Regulated by T(co)Fs:
Fosb-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
Fosb Atoh1 knockout Gastrointestinal_tissue Intestinal epithelial Lgr5(hi) stem cells 0.0531897 -4.23271 0.000111220327553141 0.00262511626266732 DataSet_11_010
Fosb Batf2 knockdown Bone_marrow Bone marrow-derived macrophages 2.46332 1.30061 2.58087047117113e-05 0.000679629224075064 DataSet_11_012
Fosb Bcl11a knockout Bone_marrow Bone marrow erythoid progenitors 0.378291 -1.40243 0.000807840954614063 0.121684866515815 DataSet_11_013
Fosb Bcl6 knockout Bone_marrow Bone marrow-derived macrophages 0.392157 -1.3505 0.0139363823930279 0.286353998832741 DataSet_11_014
Fosb Bcl6 knockout Bone_marrow Myeloid cells 0.620724 -0.687977 0.00651078658108991 0.0553670457065953 DataSet_11_015
Fosb Bhlha9 knockout Limb Whole limb bud 22.717 4.5057 - - DataSet_11_016
Fosb Cebpb knockout Mammary_gland Mammary epithlial cells (MECs) 1.98275 0.9875 0.093667352975292 0.999788745984441 DataSet_11_020
Fosb E2f4 knockout Brain Forebrain 0.373944 -1.41911 - - DataSet_11_033
Fosb Erg knockdown Bone_marrow HSPCs 0.651973 -0.617117 0.574206069137067 0.911885465121729 DataSet_11_038
Fosb Foxa2 knockout Lung Whole lung 0.576787 -0.793889 0.0677108773144564 0.453638691642465 DataSet_11_041
Fosb Gata3 siRNA Peripheral_blood CD4+ T helper (Th) cells 1.54172 0.624542 0.264860809227044 0.987135756219234 DataSet_11_048
Fosb Gfi1 knockout Cord_Blood T-cells 1.79985 0.84788 0.6062046376498 0.856065577839866 DataSet_11_053
Fosb Irf8 knockout Lymph Splenic CD11b+Gr-1 cells 2.12884 1.09007 0.0527044090531305 0.229178538807517 DataSet_11_063
Fosb Jarid2 knockout Pancreas Embryonic pancreas 4.55556 2.18763 0.0180888993466763 0.685128749167216 DataSet_11_064
Fosb Lhx8 knockout Ovary Ovary 3.2584 1.70416 0.0203633088996656 0.0791075837962097 DataSet_11_070
Fosb Lmx1b knockout Kidney Kidney 0.608466 -0.716752 0.217631718179744 0.598195073118838 DataSet_11_072
Fosb Mafg knockout Embryo Whole embryo 1.7552 0.811632 0.21864076396389 1 DataSet_11_073
Fosb Mbd2 knockout Lymph GFP+ BM leukemia cells 0.314487 -1.66893 0.0138733768575357 0.075385829028595 DataSet_11_076
Fosb Meis1 knockout Hematopoietic KSL hematopoietic cells 0.484465 -1.04554 0.161636720988286 0.995635220774426 DataSet_11_081
Fosb Meis1 knockout Bone_marrow Immortalized myeloid cell 0.475073 -1.07378 1.09711442351407e-06 2.70756842394922e-05 DataSet_11_082
Fosb Mkx knockout Tooth PDL 1.61949 0.695542 0.0522025656455843 0.999970897748702 DataSet_11_083
Fosb Neurod1 knockout Eye Retina 2.31374 1.21023 0.00154959344148136 0.0188889471610262 DataSet_11_088
Fosb Npas4 RNAi Brain Hippocampal Neurons 0.642687 -0.637811 0.587799668022439 0.797655845636679 DataSet_11_093
Fosb Nr2f2 knockout Ovary E16.5 Ovary 2.37806 1.24978 0.0381273581884758 0.376746943304818 DataSet_11_095
Fosb Nrf1 knockdown Liver Liver 4.81139 2.26645 0.000215480198344196 0.0196138856920193 DataSet_11_096
Fosb Otx2 knockout Eye Retina 2.48322 1.31221 0.649433975128234 0.999923528647439 DataSet_11_097
Fosb Pitx2 knockout Eye Cornea 0.481669 -1.05388 0.0429244143267531 0.316750896737829 DataSet_11_103
Fosb Pparg siRNA Adipose_tissue Preadipocytes 7.82342 2.9678 0.180399545272095 0.853496319463692 DataSet_11_105
Fosb Prox1 knockout Liver Liver 0.304197 -1.71692 - - DataSet_11_109
Fosb Rest shRNA Brain NSP 0.576997 -0.793363 0.702546986770017 0.999899167758865 DataSet_11_111
Fosb Runx1 knockout Lymph ProB cells 0.124794 -3.00238 0.0281322786397035 0.164253458320494 DataSet_11_116
Fosb Sall4 shRNA Embryo ES cells 0.168909 -2.56568 0.500124548469822 0.999840995136314 DataSet_11_123
Fosb Smad1 knockout Lung Lung left lobe 1.60749 0.684815 0.0688538293334231 0.542998753027287 DataSet_11_126
Fosb Smad4 siRNA Brain bEnd3 0.264439 -1.919 - - DataSet_11_127
Fosb Smad4 knockout Aorta Aortic arteries 0.288056 -1.79558 0.00623939904228053 0.133810980370349 DataSet_11_128
Fosb Snai1 knockout Embryo Embryoid body 1.59036 0.66935 - - DataSet_11_129
Fosb Sox10 siRNA Melanoma B16F10 0.479859 -1.05932 1.14085179140674e-05 0.000463136531246076 DataSet_11_136
Fosb Sox11 knockout Eye Retina 1.61539 0.691878 - - DataSet_11_137
Fosb Sox9 knockout Lung Trachea 0.621338 -0.686549 0.0302251740177426 0.219646905050619 DataSet_11_144
Fosb Sp3 knockout Heart Heart 4.27455 2.09577 0.158075363963092 0.769319272602354 DataSet_11_145
Fosb Spdef knockout Colon Colon 0.479765 -1.0596 0.162968910179753 0.997507742354799 DataSet_11_146
Fosb Spdef knockout Stomach Stomach 5.52598 2.46623 0.000644556600365196 0.344051567225484 DataSet_11_147
Fosb Srf knockout Aorta Aorta 0.446738 -1.1625 0.0932854315173183 0.993526315825099 DataSet_11_148
Fosb Srf knockout Brain Denate gyrus of hippocampus 0.387062 -1.36936 0.125605010795367 0.887411689660798 DataSet_11_149
Fosb Stat6 knockout Bone_marrow Bone marrow-derived macrophages 1.80378 0.851021 0.0222771164286503 0.0817114803382512 DataSet_11_153
Fosb Tbx1 knockout Ear Otic vesicles 0.415063 -1.2686 0.841704613447736 0.975109288105423 DataSet_11_155
Fosb Tet2 shRNA Embryo ES cells 4.19059 2.06715 - - DataSet_11_161
Fosb Thap1 knockout Brain Cerebellum 0.605406 -0.724025 2.09613804380311e-05 0.000493309281057597 DataSet_11_164
Fosb Thap1 knockout Brain Cortex 0.57322 -0.802839 0.000286794098706367 0.00479401205586657 DataSet_11_165
Fosb Vdr knockout Bone_marrow Bone marrow-derived macrophages 2.85667 1.51433 0.136875847769999 0.999827445128963 DataSet_11_174
Fosb Cpeb1 siRNA Neuron Neuro-2a 1.75424 0.810842 - - DataSet_11_189
Fosb Mapk9 knockout Hip Mouse Hip Cartilage 11.2634 3.49357 7.524977e-10 2.357492e-07 DataSet_11_236
Fosb Dnmt1 shRNA Embryo Embryonic fibroblasts 0.616438 -0.697972 - - DataSet_11_196
Fosb Ezh2 knockout Bone_marrow CD45.2+LSK cells 77415000 26.2061 - - DataSet_11_220
Fosb Ezh2 knockdown Brain Brain 9.88026 3.30455 1.862810e-06 0.0015541375 DataSet_11_221
Fosb Smarca4 shRNA Embryo ES cells 0.584946 -0.773625 - - DataSet_11_224
Fosb Smarca4 shRNA Embryo ES cells 0.584946 -0.773625 - - DataSet_11_225
Fosb Crebbp knockout Spleen Germinal center B cells 0.228227 -2.13146 5.447280e-02 0.601643163 DataSet_11_227
Fosb Bcl11b knockout Main_olfactory_epithelium main olfactory epithelium (MOE) 1.50505 0.589816 - - DataSet_11_207
Fosb Rag1 knockout Bone Mice fractured callus 1.60169 0.679593 1.760502e-06 7.384326e-05 DataSet_11_230
Fosb Dux siRNA Embryo ES cells 1.66667 0.736966 1.518185e-01 0.8774371149 DataSet_11_239
Fosb Ncl siRNA Embryo ES cells 0.6 -0.736966 2.036918e-01 0.5456712635 DataSet_11_240
Fosb Dnmt3a siRNA Embryo iPSC 1.51303 0.597443 - - DataSet_11_241
Fosb Lin28a knockout Heart Heart 0.601128 -0.734256 0.4802483907 0.8795265 DataSet_11_243
Fosb Twist1 knockout Bone_marrow stromal cells 0.518325 -0.948072 - - DataSet_11_244
Fosb Kat6a knockout Embryo Embryonic fibroblasts 0.22225 -2.16974 5.187460e-04 0.0163512178 DataSet_11_245
Fosb Fubp1 shRNA Brain brain neural progenitors 0.526325 -0.925974 0.0403461791 1 DataSet_11_246
Fosb Ezh2 knockout Calvaria calvaria 0.473273 -1.07925 2.616858e-03 0.41974329 DataSet_11_247
Fosb Dnmt1 siRNA Embryo Embryo 3 1.58496 - - DataSet_11_248
Fosb Tet1 shRNA Muscle MLL-ENL-ERtm 1.78119 0.832839 1.727205e-02 3.889940e-02 DataSet_11_249
Fosb Kmt2d knockout Skin iBiP melanoma mouse model tumor cell 73.4639 6.19896 1.458156e-07 4.263512e-05 DataSet_11_250
Fosb Mecp2 knockout Adipose_tissue brown adipose tissue 4.29787 2.10362 2.585167e-02 0.218048348 DataSet_11_253
Fosb Mecp2 knockout Adipose_tissue inguinal adipose tissue 0.520876 -0.940989 4.363609e-01 0.6733951 DataSet_11_254
Fosb Crebbp shRNA Lung preSC 0.544554 -0.876852 1.744071e-02 0.35192515 DataSet_11_255
Fosb Eed knockout Brain hindbrain 1.90148 0.927121 9.206233e-01 9.999914e-01 DataSet_11_259
Fosb Eed knockout Spinal_cord spinal cord 0.660458 -0.598461 7.200513e-01 9.999790e-01 DataSet_11_261
Fosb Arhgap35 knockout Ventral_spinal_cord Ventral spinal cord 0.563593 -0.827276 2.223213e-01 1.000000000 DataSet_11_264
Fosb Dux knockout Embryo Embryo 1.92129 0.942073 1.625987e-01 3.262975e-01 DataSet_11_269
Fosb Mef2d CRISPR Heart Cardiac ventricle 0.188304 -2.40886 6.821705e-02 0.2716493684 DataSet_11_270
Fosb Kat6b shRNA Bone_marrow LT-HSCs 1.86705 0.900762 6.646427e-02 0.5927415 DataSet_11_271
Fosb Myc CRISPR Skeletal_muscle muscle stem cells 2.81452 1.49289 1.154718e-01 0.81420760 DataSet_11_272
Fosb Dux knockout Embryo Embryo 1.92129 0.942073 1.625986e-01 3.262975e-01 DataSet_11_273
Fosb Lin28b knockout Bone_marrow Bone marrow immature B cells 2.39509 1.26008 3.288279e-02 0.9643594 DataSet_11_274
Fosb Ezh2 siRNA Bone_marrow Mesenchymal stem cells 1.71429 0.777608 3.032122e-03 5.111460e-02 DataSet_11_276
Fosb Zmat3 knockout Embryo Embryonic fibroblasts 3.02622 1.59752 2.310793e-02 0.5395938 DataSet_11_284
Fosb Pdx1 CRISPR Liver Liver 0.235294 -2.08746 6.576369e-04 0.212263481 DataSet_11_286
Fosb Fli1 CRISPR Lymph CD8 T cells 2.33684 1.22456 4.903550e-01 0.9999740103 DataSet_11_288
Fosb Mkl1 knockout Bone_marrow Bone marrow differentiated macrophages 1.69048 0.75743 9.469299e-02 0.4912687513 DataSet_11_294
Fosb Tfap2a knockout Brain Brain 0.473433 -1.07877 0.1571238282 0.9599640 DataSet_11_295
Fosb Ssrp1 CRISPR Embryo ES cells 2.46154 1.29956 5.553166e-02 0.29050623 DataSet_11_296
Fosb Phf8 knockout prostate Prostate 2.26429 1.17906 0.2995236339 0.5478440 DataSet_11_298
Fosb Hmg20a siRNA Hypothalamus Primary hypothalamic astrocytes 0.485549 -1.04231 0.0159921138 0.2501520 DataSet_11_300
Fosb Arid2 knockout Muscle LSK 0.504262 -0.987755 8.429327e-02 9.229543e-01 DataSet_11_301
Fosb Dnmt1 knockout Skin Keratinocytes 1.95552 0.967554 3.901945e-03 0.0745639091 DataSet_11_303
Fosb Satb2 CRISPR Colon Colon organoid 0.53125 -0.912537 2.359771e-01 0.6518149 DataSet_11_304
Fosb Myc CRISPR Skeletal_muscle quiescent muscle stem cell 18.6843 4.22375 1.456845e-02 0.31507703 DataSet_11_310
Fosb Suz12 knockout Lung Alveolar macrophage 2.9777 1.5742 3.189445e-03 4.009206e-02 DataSet_11_312
Fosb Irf7 knockout Bone_marrow c-kit+ leukemic cells 0.271177 -1.88269 - - DataSet_11_313
Fosb Arid2 knockout Bone_marrow bone marrow leukemia cells 133.743 7.06332 5.358437e-01 0.8201669 DataSet_11_318
Fosb Kat7 knockout Thymic_lobes Thymic epithelial cells 0.457851 -1.12705 4.561528e-01 6.528112e-01 DataSet_11_320
Fosb Setdb1 shRNA Neuron NE-4C 6.26606 2.64756 - - DataSet_11_323
Fosb Kdm5b siRNA Embryo ES cells 0.560515 -0.835176 0.3460359444 0.8933528 DataSet_11_331
Fosb Ezh2 shRNA Brain SVZ derived neural stem cells 3.21939 1.68679 7.850036e-01 8.897531e-01 DataSet_11_332
Fosb Ezh2 knockout Eye Retina 0.247194 -2.01628 0.1834756035 1.0000000 DataSet_11_334
Fosb Dnmt3a knockout Peritoneum peritoneal macrophages 2.72183 1.44458 - - DataSet_11_336
Fosb Dnmt1 siRNA Heart embryonic cardiomyocytes 0.645374 -0.631792 1.155929e-01 0.205265306 DataSet_11_340
Fosb Ezh2 knockout Small_intestinal_crypts small intestinal crypts 3.25 1.70044 0.0668197110 0.1712697 DataSet_11_341
Fosb Hnrnpk siRNA Embryo ES cells 1.72149 0.783657 1.468148e-03 0.008573956 DataSet_11_342
Fosb Pcbp1 shRNA Thymus Th1 1.86957 0.902703 2.414923e-02 0.13371725 DataSet_11_343
Fosb Dux shRNA Embryo ES cells 1.58108 0.660911 5.947460e-01 8.489104e-01 DataSet_11_345
Regulation Region
 
T(co)Fs that significantly regulate Crebbp by the evidences of both expression and ChIP-seq/motif
Expression Atlas of Fosb
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)