Gene Overview
Target Gene: NELL2
NCBI Official Symbol: NELL2
Entrez ID: 4753
Ensembl ID: ENSG00000184613
Gene Full Name: neural EGFL like 2
Strand: -
Gene Locus: 12q12
External Links:

NELL2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate NELL2   
T(co)Fs that Repress NELL2
The Intensity of the Gene Regulated by T(co)Fs:
NELL2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
NELL2 FOXA1 shRNA Prostate 22RV1 0.36514 -1.45349 - - DataSet_01_105
NELL2 ZIC2 siRNA Pancreas PANC1 0.43459 -1.20228 - - DataSet_01_121
NELL2 FOXM1 siRNA Central_nervous_system U87 0.03303 -4.92008 - - DataSet_01_122
NELL2 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.54414 0.62681 0.25809 0.99993 DataSet_01_137
NELL2 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.87551 0.90728 0.1048 0.99993 DataSet_01_138
NELL2 SF1 siRNA Adrenal_gland H295R/TR 1.59495 0.67351 5.54039e-05 0.00171 DataSet_01_146
NELL2 MYCN siRNA Autonomic_ganglia SKNBE2 2.34278 1.22822 0.00103 0.0624 DataSet_01_160
NELL2 ELK1 siRNA Peripheral_blood CD4+ T cells 0.00354 -8.14226 0.33316 0.55855 DataSet_01_162
NELL2 GATA3 siRNA Peripheral_blood CD4+ T cells 0.00662 -7.23975 0.60984 0.82536 DataSet_01_163
NELL2 JUN siRNA Peripheral_blood CD4+ T cells 0.00371 -8.07615 0.35591 0.62068 DataSet_01_164
NELL2 MAF siRNA Peripheral_blood CD4+ T cells 0.00255 -8.61445 0.23561 0.58851 DataSet_01_165
NELL2 NFATC3 siRNA Peripheral_blood CD4+ T cells 0.0039 -8.00192 0.36901 0.66932 DataSet_01_166
NELL2 NFKB1 siRNA Peripheral_blood CD4+ T cells 0.00544 -7.52342 0.51082 0.85052 DataSet_01_167
NELL2 STAT3 siRNA Peripheral_blood CD4+ T cells 0.0043 -7.86012 0.4021 0.99183 DataSet_01_168
NELL2 HOXB7 siRNA Pancreas Capan-1 0.44803 -1.15834 0.01521 0.44872 DataSet_01_170
NELL2 TP53 siRNA Lung SAECs 1.74204 0.80078 0.12757 0.53717 DataSet_01_175
NELL2 NR5A2 siRNA Mammary_gland MCF7 0.3376 -1.5666 6.48077e-12 1.54344e-08 DataSet_01_182
NELL2 CREB1 shRNA Parotid_gland H3118 MEC 0.42842 -1.2229 0.00049 0.09351 DataSet_01_194
NELL2 TP63 siRNA Immortalized_keratinocyte HaCaT RG 0.40916 -1.28925 - - DataSet_01_196
NELL2 TP63 siRNA Head_and_neck SCC-1 0.49169 -1.02419 - - DataSet_01_198
NELL2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 1.61578 0.69223 - - DataSet_01_209
NELL2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.06556 -3.93094 - - DataSet_01_210
NELL2 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 2.22851 1.15608 0.00017 0.00648 DataSet_01_217
NELL2 SNAI2 shRNA Skin Primary human keratinocytes 2.49452 1.31876 0.00015 0.00859 DataSet_01_225
NELL2 ARNT shRNA Embryo hESC HSF1 0.53655 -0.89821 0.11155 0.99999 DataSet_01_240
NELL2 MYT1L shRNA Fetal_spinal_cord SPC04 0.40528 -1.30302 0.00143 0.08549 DataSet_01_264
NELL2 MEF2A shRNA Fetal_spinal_cord SPC04 2.46678 1.30263 0.01351 0.89906 DataSet_01_265
NELL2 HES1 shRNA Haematopoietic_and_lymphoid_tissue_Blood CUTLL1 2.19406 1.1336 3.85238e-07 8.79626e-05 DataSet_01_266
NELL2 SIX4 siRNA Ovary PEO1 0.63066 -0.66507 0.0136 0.08348 DataSet_01_269
NELL2 SALL4 shRNA Lung H661 2.15102 1.10502 0.00058 0.03585 DataSet_01_277
NELL2 AR shRNA Prostate CWR22Pc 3.05209 1.6098 3.26472e-05 0.00356 DataSet_01_278
NELL2 STAT5 shRNA Prostate CWR22Pc 2.41593 1.27258 8.10288e-05 0.00605 DataSet_01_279
NELL2 ZIC5 siRNA Skin A375 0.64484 -0.63298 - - DataSet_01_284
NELL2 SNAI2 siRNA Mammary_gland MCFDCIS 2.32304 1.21602 0.0219 0.48191 DataSet_01_292
NELL2 POSTN shRNA Brain GSC272 1.97284 0.98027 0.12237 0.55804 DataSet_01_293
NELL2 TFAP4 siRNA Brain BE(2)-C 0.21334 -2.22875 0.36325 0.51625 DataSet_01_295
NELL2 SOX17 siRNA Umbilical_vein HUVEC 3.42921 1.77787 0.00229 0.79966 DataSet_01_300
NELL2 PTEN shRNA Lung HCC827 2.63871 1.39984 0.29219 0.72188 DataSet_01_302
NELL2 PTEN shRNA Mammary_gland SKBR3 0.41212 -1.27888 0.2955 0.72338 DataSet_01_303
NELL2 ARNT siRNA Upper_aerodigestive_tract HSC3 2.30916 1.20737 - - DataSet_01_315
NELL2 ELK3 shRNA Mammary_gland MDA-MB-231 6.06319 2.60008 3.33444e-07 1.92468e-05 DataSet_01_318
NELL2 ETV4 shRNA Prostate PC3 1.53356 0.61688 - - DataSet_01_356
NELL2 GTF2B siRNA Cervix HeLa 2.77651 1.47328 - - DataSet_01_362
NELL2 FIP1L1 shRNA Liver HepG2 0.05882 -4.08746 0.00949 0.03998 DataSet_02_103
NELL2 TAF15 shRNA Liver HepG2 0.5 -1 0.0637 0.1072 DataSet_02_106
NELL2 BCLAF1 shRNA Liver HepG2 2.5 1.32193 0.04502 0.11325 DataSet_02_112
NELL2 TARDBP shRNA Liver HepG2 0.64286 -0.63743 0.13075 0.20797 DataSet_02_116
NELL2 SUB1 shRNA Liver HepG2 10 3.32193 0.01313 0.14118 DataSet_02_117
NELL2 PTBP1 shRNA Liver HepG2 0.5 -1 0.05658 0.08476 DataSet_02_120
NELL2 FUS shRNA Liver HepG2 10.5 3.39232 0.01552 0.10654 DataSet_02_124
NELL2 SNRNP70 shRNA Liver HepG2 0.5 -1 0.08237 0.1664 DataSet_02_126
NELL2 SRSF3 shRNA Liver HepG2 1.64286 0.71621 0.1732 0.32118 DataSet_02_127
NELL2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.98864 0.99178 0.97701 1 DataSet_02_129
NELL2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.22727 -2.1375 0.03145 0.08394 DataSet_02_131
NELL2 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.3886 -1.36364 0.17954 0.34152 DataSet_02_132
NELL2 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 1.625 0.70044 0.02126 0.11356 DataSet_02_134
NELL2 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 1.68182 0.75002 0.05037 0.22191 DataSet_02_136
NELL2 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.16667 1.11548 0.98994 1 DataSet_02_139
NELL2 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.52381 1.3356 0.41498 0.64218 DataSet_02_140
NELL2 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.51685 0.60108 0.38826 0.5636 DataSet_02_142
NELL2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.63212 -0.66172 0.51324 0.70397 DataSet_02_144
NELL2 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.56115 -0.83354 0.33876 0.6408 DataSet_02_145
NELL2 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.47475 -1.07477 0.02087 0.47274 DataSet_02_146
NELL2 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 2.11111 1.078 0.20566 0.49448 DataSet_02_148
NELL2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.65591 -0.60842 0.40266 0.59138 DataSet_02_149
NELL2 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48387 -1.04731 0.09815 0.53252 DataSet_02_150
NELL2 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.65468 -0.61115 0.4817 0.64358 DataSet_02_151
NELL2 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.5 1.32193 0.01265 0.25114 DataSet_02_152
NELL2 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 1.96552 0.97491 0.2156 0.5196 DataSet_02_154
NELL2 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.64789 -0.62619 0.6093 0.77311 DataSet_02_155
NELL2 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57471 -0.79909 0.63256 0.99879 DataSet_02_157
NELL2 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.71264 0.77623 0.26673 0.82744 DataSet_02_161
NELL2 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 0.57746 -0.7922 0.525 0.69787 DataSet_02_164
NELL2 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.84127 1.50654 0.03266 0.10764 DataSet_02_170
NELL2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 2.49206 1.31734 0.15246 0.35415 DataSet_02_171
NELL2 ZFX siRNA Prostate C4-2B 3.29412 1.71989 0.04275 0.09333 DataSet_02_172
NELL2 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 3.38667 1.75987 0.07209 1 DataSet_02_176
NELL2 ZNF180 siRNA Haematopoietic_and_lymphoid_tissue K562 1.64062 0.71425 0.19102 1 DataSet_02_177
NELL2 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42941 -1.21957 0.03329 1 DataSet_02_180
NELL2 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.64151 -0.64046 0.34298 1 DataSet_02_181
NELL2 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 1.61728 0.69357 0.43707 1 DataSet_02_182
NELL2 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.44 2.15056 0.07164 1 DataSet_02_188
NELL2 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 2.73333 1.45066 0.0544 1 DataSet_02_189
NELL2 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.56 0.64155 0.22367 1 DataSet_02_192
NELL2 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.78667 0.83727 0.15858 1 DataSet_02_195
NELL2 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.52 0.60407 0.29686 1 DataSet_02_197
NELL2 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.60377 -0.72792 0.13215 1 DataSet_02_198
NELL2 MAZ siRNA Haematopoietic_and_lymphoid_tissue K562 1.52066 0.6047 0.15995 1 DataSet_02_199
NELL2 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.65079 0.72316 0.33724 1 DataSet_02_204
NELL2 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 3.17333 1.666 0.03974 1 DataSet_02_205
NELL2 ABL1 siRNA Mammary_gland MCF7 0.482393 -1.05172 0.0922903507015744 0.976385569407162 DataSet_03_001
NELL2 AKT1 siRNA Mammary_gland MCF7 0.448963 -1.15533 0.0698781932406777 0.937512920166337 DataSet_03_002
NELL2 ATR siRNA Mammary_gland MCF7 0.461325 -1.11615 0.0776261872807197 0.999819450785634 DataSet_03_020
NELL2 BCL6 siRNA Mammary_gland MCF7 0.357923 -1.48228 0.0294379251411541 0.989541443114508 DataSet_03_024
NELL2 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.641523 -0.640427 0.276411627090088 0.845198218672105 DataSet_03_025
NELL2 BRCA2 siRNA Mammary_gland MCF7 0.447434 -1.16025 0.0689622417559741 0.999441861952364 DataSet_03_029
NELL2 CCNA2 siRNA Mammary_gland MCF7 0.480758 -1.05662 0.0910841619785637 0.872422373040044 DataSet_03_034
NELL2 CDK2 siRNA Mammary_gland MCF7 0.512055 -0.965628 0.116257657382658 0.99987175116756 DataSet_03_044
NELL2 CEBPB siRNA Mammary_gland MCF7 0.477486 -1.06647 0.0887058017445438 0.993756826434039 DataSet_03_048
NELL2 CEBPB siRNA Embryo hESC 3.09655 1.63066 0.0124027199912398 0.243170828828245 DataSet_03_049
NELL2 CEBPD siRNA Mammary_gland MCF7 0.433791 -1.20493 0.0611863684576706 0.999848455332859 DataSet_03_050
NELL2 CENPF siRNA Mammary_gland MCF7 1.53822 0.621265 0.284809302212998 0.999662524742916 DataSet_03_052
NELL2 CHEK1 siRNA Mammary_gland MCF7 0.450401 -1.15072 0.0707482188819533 0.999587656258211 DataSet_03_053
NELL2 CREBBP siRNA Mammary_gland MCF7 0.587511 -0.767312 0.196401383773824 0.966455540764243 DataSet_03_055
NELL2 CTNNB1 siRNA Mammary_gland MCF7 1.98001 0.985505 0.110232272016582 0.999436862066063 DataSet_03_058
NELL2 E2F1 siRNA Mammary_gland MCF7 1.7681 0.8222 0.170152108064627 0.999927373439084 DataSet_03_061
NELL2 E2F5 siRNA Mammary_gland MCF7 1.61455 0.691133 0.238922319161861 0.999540347732068 DataSet_03_062
NELL2 ERBB2 siRNA Mammary_gland MCF7 0.512794 -0.963548 0.116906273852977 0.998282799776643 DataSet_03_066
NELL2 ERF siRNA Mammary_gland MCF7 0.397293 -1.33172 0.0436649710779878 0.999855523449227 DataSet_03_067
NELL2 ESR1 siRNA Mammary_gland MCF7 0.648091 -0.625732 0.178557229199665 0.999753934970283 DataSet_03_068
NELL2 FOS siRNA Mammary_gland MCF7 0.465834 -1.10211 0.080607408975179 0.999966427400474 DataSet_03_079
NELL2 FOXC1 siRNA Mammary_gland MCF7 0.417734 -1.25934 0.0529137458670939 0.999669928105298 DataSet_03_084
NELL2 FOXJ2 siRNA Mammary_gland MCF7 0.40992 -1.28658 0.0492149528012005 0.999965704179325 DataSet_03_088
NELL2 FOXP1 siRNA Mammary_gland MCF7 0.345393 -1.53369 0.0257816368453056 0.999975993110711 DataSet_03_099
NELL2 GATA4 siRNA Stomach AGS 0.50492 -0.985874 0.392431321005364 0.898636693256255 DataSet_03_105
NELL2 GATA4 siRNA Stomach YCC3 2.79395 1.4823 0.119087729461722 0.668467976761717 DataSet_03_107
NELL2 GATA6 siRNA Stomach YCC3 3.19491 1.67578 0.105871732963686 0.724906809292463 DataSet_03_110
NELL2 HDAC3 siRNA Mammary_gland MCF7 0.3928 -1.34813 0.041812365860056 0.99997791025972 DataSet_03_114
NELL2 HDAC5 siRNA Mammary_gland MCF7 1.63945 0.713216 0.225824155766758 0.999966625300244 DataSet_03_115
NELL2 HIF1A siRNA Mammary_gland MCF7 0.331168 -1.59437 0.0220788741018574 0.999966843283762 DataSet_03_119
NELL2 HSF2 siRNA Mammary_gland MCF7 1.5275 0.611175 0.292017650027331 0.990969613280381 DataSet_03_130
NELL2 ID1 siRNA Mammary_gland MCF7 0.393335 -1.34617 0.0420299121283451 0.999926480273844 DataSet_03_133
NELL2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.242532 -2.04375 0.0722206105045074 0.903854087586468 DataSet_03_134
NELL2 JUN siRNA Mammary_gland MCF7 0.51324 -0.962294 0.174931614999536 0.999857657786768 DataSet_03_142
NELL2 JUND siRNA Mammary_gland MCF7 0.56973 -0.811649 0.117299045102101 0.999848956486105 DataSet_03_145
NELL2 Klf4 siRNA Skin Primary neonatal keratinocytes 2.30103 1.20228 0.0175852864664073 0.0664688958821809 DataSet_03_147
NELL2 KLF5 siRNA Stomach KatoIII 0.631463 -0.66323 0.579472263742709 0.862793720527252 DataSet_03_150
NELL2 KLF5 siRNA Stomach YCC3 1.86969 0.902798 0.480195350750197 0.787134894644911 DataSet_03_151
NELL2 MAPK1 siRNA Mammary_gland MCF7 0.459306 -1.12247 0.244260476721516 0.999829384224364 DataSet_03_156
NELL2 MAPK14 siRNA Mammary_gland MCF7 0.623112 -0.682436 0.0763192184361298 0.999824418484635 DataSet_03_157
NELL2 MAX siRNA Mammary_gland MCF7 0.440286 -1.18349 0.0648000900370537 0.999907009675999 DataSet_03_158
NELL2 MCM2 siRNA Mammary_gland MCF7 0.444396 -1.17008 0.0671688301780512 0.999925560383539 DataSet_03_161
NELL2 MEF2D shRNA Liver HuH7 1.53758 0.620665 - - DataSet_03_162
NELL2 MITF siRNA Skin Ma-Mel-15 3.73978 1.90295 0.0157255383023511 0.25838668318864 DataSet_03_166
NELL2 MITF siRNA Skin Ma-Mel-15 2.96527 1.56816 0.00561695631096776 0.0955523767953886 DataSet_03_167
NELL2 MYB siRNA Cord_Blood CD34+ progenitor cells 17.1559 4.10063 - - DataSet_03_170
NELL2 MYB siRNA Prostate PC-3M 1.52591 0.609667 1.69088817834918e-06 0.000160296199307503 DataSet_03_173
NELL2 MYBL2 siRNA Mammary_gland MCF7 0.441509 -1.17948 0.0654982538627117 0.999907476570542 DataSet_03_176
NELL2 MYC siRNA Colon HT29 2.27976 1.18888 - - DataSet_03_177
NELL2 MYC siRNA Central_nervous_system DAOY M2.1 0.504384 -0.987406 5.07010392662767e-08 1.01625638814895e-06 DataSet_03_178
NELL2 MYC siRNA Mammary_gland MCF7 0.317493 -1.6552 0.0189322362044123 0.999887767096734 DataSet_03_182
NELL2 MYCN siRNA Autonomic_ganglia SKNBE2 2.34278 1.22822 0.000965155909073094 0.0633342845014392 DataSet_03_185
NELL2 NCOR2 siRNA Mammary_gland MCF7 0.322471 -1.63276 0.0200331558680653 0.999834929103349 DataSet_03_193
NELL2 NFKB1 siRNA Mammary_gland MCF7 0.634965 -0.65525 0.299327304496579 0.999910999317747 DataSet_03_196
NELL2 NMI siRNA Mammary_gland MCF7 0.372741 -1.42375 0.0342803245998532 0.695728433887744 DataSet_03_199
NELL2 PAX3 siRNA Mammary_gland MCF7 0.431888 -1.21127 0.0717477910013604 0.919978041032696 DataSet_03_206
NELL2 PHB shRNA Embryo Embryonic stem cells (ESCs) 0.403758 -1.30844 5.68307929793618e-06 0.00028226492555346 DataSet_03_211
NELL2 RBL2 siRNA Mammary_gland MCF7 0.261437 -1.93546 0.0095497927717049 0.999927471951507 DataSet_03_220
NELL2 RELA siRNA Mammary_gland MCF7 0.424174 -1.23727 0.0561208673560342 0.999993711976373 DataSet_03_224
NELL2 SMAD7 siRNA Mammary_gland MCF7 0.360463 -1.47208 0.0302271013805108 0.99858912864726 DataSet_03_234
NELL2 SOX11 siRNA Lung_fibroblast NHLF 0.520772 -0.941277 0.233725703687256 0.605255706106144 DataSet_03_238
NELL2 SOX2 siRNA Lung H520 0.657948 -0.603954 - - DataSet_03_240
NELL2 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 4 2 - - DataSet_03_246
NELL2 SP1 siRNA Ovary OVSAYO 2.23465 1.16005 0.00348707744086892 0.092045109245416 DataSet_03_251
NELL2 STAT1 siRNA Mammary_gland MCF7 0.430058 -1.2174 0.0591801350226984 0.999890411872485 DataSet_03_256
NELL2 STAT3 CRISPR Embryo hESC 6.89796 2.78617 0.00838224508825672 0.0600346914830632 DataSet_03_258
NELL2 STAT5B siRNA Mammary_gland MCF7 1.52231 0.606264 0.295581180589824 0.999932708473107 DataSet_03_263
NELL2 STAT6 siRNA Umbilical_vein HUVEC 2.31818 1.21299 0.310671540351501 0.876741320594925 DataSet_03_264
NELL2 TET1 siRNA Embryo NCCIT 1.85964 0.895025 1.04047179998424e-05 0.00163853217852923 DataSet_03_269
NELL2 TET2 siRNA Embryo NCCIT 1.95769 0.969155 6.04476649627996e-06 0.000769865424747524 DataSet_03_270
NELL2 TFAP2C siRNA Mammary_gland MCF7 0.0824958 -3.59954 0.0109705653987147 0.274962492718944 DataSet_03_274
NELL2 TP53 siRNA Mammary_gland MCF7 1.5162 0.600456 0.299842542592681 0.999938217444253 DataSet_03_277
NELL2 TP63 siRNA Skin Primary neonatal keratinocytes 0.520533 -0.941939 0.00880667470395449 0.0442210107343044 DataSet_03_281
NELL2 WT1 siRNA Mammary_gland MCF7 0.344231 -1.53855 0.0254618545533987 0.999957852801679 DataSet_03_285
NELL2 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.627737 -0.671767 0.623836330504555 0.960995628452088 DataSet_04_003
NELL2 MARK2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.51938 -0.945138 0.139997426764864 0.20300033141575 DataSet_04_012
NELL2 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 11.8699 3.56923 0.52757648745331 0.658689817483835 DataSet_04_014
NELL2 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.344037 -1.53937 0.0147850012950689 0.774600056591563 DataSet_04_016
NELL2 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.574257 -0.800231 0.00270262081172125 0.0786343354168621 DataSet_04_018
NELL2 YBX1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.331551 -1.5927 0.0266792623819315 0.482324531218369 DataSet_04_022
NELL2 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.36923 1.24442 0.0509695533384884 0.173413499892311 DataSet_04_023
NELL2 CNOT7 CRISPR Liver HepG2 0.125 -3 0.06828001956619 0.163927245034496 DataSet_04_045
NELL2 DNMT3B CRISPR Liver HepG2 0.222222 -2.16992 0.398642935764394 0.661691926081369 DataSet_04_044
NELL2 PAN2 CRISPR Liver HepG2 2 1 0.872637855480856 0.938959587947303 DataSet_04_066
NELL2 SEPT11 CRISPR Liver HepG2 1.8 0.847997 0.680712087658002 0.855404571846975 DataSet_04_068
NELL2 ABT1 shRNA Liver HepG2 4.66667 2.22239 0.493610363505829 0.621636754623897 DataSet_04_052
NELL2 PRPF6 shRNA Liver HepG2 5.5 2.45943 0.512828143930214 0.718625412078833 DataSet_04_056
NELL2 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.62 -0.68966 0.0384452499574189 0.384470368235233 DataSet_04_050
NELL2 RIOK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.44382 -1.17195 0.198012576256836 0.706568458113352 DataSet_04_076
NELL2 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.593985 -0.751502 0.0233510842141562 0.0737331800714771 DataSet_04_049
NELL2 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.76712 1.46839 0.0154026422160767 0.0595949024230599 DataSet_02_34
NELL2 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.256684 -1.96193 0.00713182231592267 0.393478982766751 DataSet_02_75
NELL2 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.0274 2.00985 0.224721239858003 0.697712433509231 DataSet_02_45
NELL2 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.13014 1.09095 0.0347475619654569 0.358160464954038 DataSet_02_32
NELL2 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.21127 1.14487 0.0802005072426221 0.469067238767892 DataSet_02_49
NELL2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.61644 0.692818 0.185686479866839 0.315209401715112 DataSet_02_33
NELL2 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.79452 0.843598 0.335165349455531 0.505226876749576 DataSet_02_53
NELL2 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.62844 -0.670152 0.0347942212562581 0.106637565245185 DataSet_04_060
NELL2 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.310078 -1.6893 0.0570644398485646 0.11312437144103 DataSet_04_059
NELL2 CNOT3 shRNA Lung A549 1.90292 0.928216 7.687269e-02 0.8830540 DataSet_03_340
NELL2 EZH2 shRNA Colon SW480 5.4566 2.448 - - DataSet_03_298
NELL2 EZH2 knockdown Uterus Ishikawa (ISK) cell 1.78592 0.836667 - - DataSet_03_324
NELL2 SNAI2 shRNA Pancreas KLM1 0.416387 -1.264 8.083562e-02 0.37534823 DataSet_03_307
NELL2 INO80 siRNA Muscle RD 1.60135 0.67929 - - DataSet_03_344
NELL2 BRCA1 siRNA Mammary_gland MCF7 0.652617 -0.615692 2.993673e-02 0.9999931 DataSet_03_308
NELL2 SKI CRISPR Blood HL60 0.111111 -3.16992 3.122884e-03 0.109886717 DataSet_03_351
NELL2 TET1 CRISPR Mammary_gland Hs578T 0.0956979 -3.38537 3.010091e-01 4.987329e-01 DataSet_03_355
NELL2 PTPN14 CRISPR Brain U5-NPC 0.076972 -3.69952 4.428686e-04 0.10177838 DataSet_03_357
NELL2 NCOA2 siRNA Uterus endometrial stromal cells 0.307692 -1.70044 0.4177809815 1 DataSet_03_360
NELL2 NCOA3 siRNA Mammary_gland MDA-MB-231 1.82309 0.866387 3.737590e-01 0.8474628 DataSet_03_361
NELL2 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 0.458542 -1.12487 5.088834e-04 2.018696e-03 DataSet_03_362
NELL2 TPR shRNA Bone_marrow U2OS 0.601728 -0.732817 2.288727e-03 6.083080e-02 DataSet_03_370
NELL2 BHLHE40 shRNA Cervix HeLaS3 2.1227 1.0859 2.865712e-01 0.84447131 DataSet_03_372
NELL2 HNRNPU siRNA Colon RKO 1.59779 0.676079 - - DataSet_03_374
NELL2 EZH2 CRISPR Ovary SKOV3 0.25974 -1.94486 1.159051e-02 0.0828070811 DataSet_03_378
NELL2 NFKB2 siRNA Bone_marrow U2OS 0.613014 -0.706009 3.957940e-02 0.26168415 DataSet_03_381
NELL2 DNMT1 siRNA Skin Human melanoma cells 4.29869 2.1039 4.057261e-02 7.326821e-02 DataSet_03_382
NELL2 YY1 shRNA Brain GSC1517 3 1.58496 - - DataSet_03_384
NELL2 NFKBIA shRNA Bone_marrow U2OS 0.497883 -1.00612 4.679529e-01 0.87005461 DataSet_03_389
NELL2 RELA CRISPR Brain T30 0.330227 -1.59847 0.0689145286 0.8400824 DataSet_03_399
NELL2 EHF shRNA Stomach MKN7 0.316393 -1.66021 - - DataSet_03_402
NELL2 TFAP2A knockout Embryo H9 1.9814 0.986517 1.980149e-02 0.08930662 DataSet_03_405
NELL2 E2F6 shRNA Liver HuH7 2.32806 1.21913 - - DataSet_03_412
NELL2 E2F1 siRNA Prostate LNCaP 0.641221 -0.641106 1.281661e-01 0.6731381120 DataSet_03_413
NELL2 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 0.596154 -0.746243 1.425945e-01 0.322528149 DataSet_03_418
NELL2 PRDM1 CRISPR Lymph CD8+ T cells 0.593202 -0.753404 - - DataSet_03_421
NELL2 FOXQ1 CRISPR Lymph Primary CD4+ T cells 0.63187 -0.662299 - - DataSet_03_422
NELL2 FOXP3 CRISPR Peripheral_blood Naive Treg 0.0470152 -4.41073 1.541686e-02 0.196838510 DataSet_03_427
NELL2 LHX2 shRNA Bone_marrow ES-derived RPE cells 0.472745 -1.08086 6.870583e-02 1.000000e+00 DataSet_03_428
NELL2 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 2.4 1.26303 0.5724168281 1 DataSet_03_430
NELL2 USP7 shRNA Skin xenograft cells 0.435549 -1.19909 0.25080674 0.4348960 DataSet_03_431
NELL2 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 8 3 - - DataSet_03_432
NELL2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 2.35576 1.23619 1.071059e-02 0.314164072 DataSet_03_434
NELL2 SUFU shRNA Mammary_gland HCC1954 cells 2.2 1.1375 0.0906361637 0.6302712 DataSet_03_437
NELL2 CIC knockout Brain Immortalized Astrocyte Cells 2.54688 1.34873 3.375097e-01 7.541883e-01 DataSet_03_438
NELL2 HMG20A siRNA Mammary_gland MDA-MB-231 2 1 0.1526560443 0.4087570 DataSet_03_442
NELL2 PHF14 siRNA Mammary_gland MDA-MB-231 4.02941 2.01057 0.0117373921 0.2772439 DataSet_03_443
NELL2 RELB CRISPR Colon SW480 1.65678 0.728386 5.512369e-02 2.071636e-01 DataSet_03_449
NELL2 CBX2 siRNA Mammary_gland MDA-MB-231 0.567979 -0.816091 4.717249e-02 1.446401e-01 DataSet_03_450
NELL2 CBX2 siRNA Mammary_gland MCF7 77.5519 6.27709 1.154206e-06 0.0002617204 DataSet_03_451
NELL2 SMARCA2 shRNA Lung HCC2302 14.9408 3.90118 2.807576e-12 4.031238e-11 DataSet_03_455
NELL2 PARP1 knockout Embryo_kidney HEK293a 3.9882 1.99574 4.599772e-15 2.213759e-12 DataSet_03_464
NELL2 STAT3 shRNA Liver HepG2 0.125 -3 2.598606e-05 0.0050418533 DataSet_03_465
NELL2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.541703 -0.884425 - - DataSet_03_466
NELL2 CREBBP CRISPR Lymph U2932 2 1 5.350113e-01 1.0000000 DataSet_03_474
NELL2 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.627737 -0.671767 0.4620616 0.9378253 DataSet_04_071
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of NELL2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines