Gene Overview
Target Gene: PSG1
NCBI Official Symbol: PSG1
Entrez ID: 5669
Ensembl ID: ENSG00000231924
Gene Full Name: pregnancy specific beta-1-glycoprotein 1
Strand: -
Gene Locus: 19q13.2
External Links:

PSG1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PSG1   
T(co)Fs that Repress PSG1
The Intensity of the Gene Regulated by T(co)Fs:
PSG1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PSG1 ID1 siRNA Lung H1650 1.80266 0.85013 0.08074 0.41701 DataSet_01_118
PSG1 BRD4 shRNA Embryo_kidney HEK293 1.77707 0.8295 - - DataSet_01_119
PSG1 ZIC2 siRNA Pancreas PANC1 1.65526 0.72706 - - DataSet_01_121
PSG1 FOXM1 siRNA Central_nervous_system U87 4.27462 2.0958 - - DataSet_01_122
PSG1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.53247 0.61586 0.26834 0.99993 DataSet_01_138
PSG1 TEAD4 shRNA Stomach SNU216 0.40006 -1.32171 - - DataSet_01_151
PSG1 HSF1 shRNA Skin A375 2.32159 1.21511 0.00116 0.01392 DataSet_01_155
PSG1 NFATC3 siRNA Peripheral_blood CD4+ T cells 16.1014 4.00911 0.13027 0.37988 DataSet_01_166
PSG1 HOXB7 siRNA Pancreas Capan-1 0.59121 -0.75825 0.0124 0.4306 DataSet_01_170
PSG1 ESRRG siRNA Placenta_tissue Trophoblast cells 0.42042 -1.25011 0.00396 0.07395 DataSet_01_173
PSG1 TP53 siRNA Lung SAECs 0.51511 -0.95706 0.02462 0.32173 DataSet_01_175
PSG1 CREB1 shRNA Parotid_gland H3118 MEC 2.2426 1.16517 0.19811 0.56113 DataSet_01_194
PSG1 TP63 siRNA Immortalized_keratinocyte HaCaT RG 1.83333 0.87447 - - DataSet_01_196
PSG1 TP63 siRNA Immortalized_keratinocyte HaCaT 2.26259 1.17797 - - DataSet_01_200
PSG1 TP63 siRNA Head_and_neck SCC-012 1.75306 0.80987 - - DataSet_01_201
PSG1 TP63 siRNA Head_and_neck SCC-6 1.54273 0.62548 - - DataSet_01_202
PSG1 XBP1 shRNA Mammary_gland MDA-MB-231 1.74829 0.80594 0.0015 0.02194 DataSet_01_204
PSG1 HIC1 shRNA Mammary_gland HBL100 2.96347 1.56729 - - DataSet_01_205
PSG1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 1.59261 0.67139 - - DataSet_01_208
PSG1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 2.54333 1.34672 - - DataSet_01_209
PSG1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.6426 -0.63801 - - DataSet_01_210
PSG1 IRX1 shRNA Bone_marrow 143B 2.29282 1.19712 0.44894 0.6808 DataSet_01_227
PSG1 TWIST1 shRNA Stomach CAF14 0.43744 -1.19283 0.1302 0.99996 DataSet_01_252
PSG1 TWIST1 shRNA Stomach CAF32 0.40682 -1.29755 0.00056 0.01672 DataSet_01_253
PSG1 TWIST1 shRNA Stomach CAF 0.42185 -1.24519 0.00864 0.52717 DataSet_01_254
PSG1 AR shRNA Prostate CWR22Pc 0.46267 -1.11193 0.21204 0.42887 DataSet_01_278
PSG1 STAT5 shRNA Prostate CWR22Pc 0.22205 -2.17102 0.05743 0.16436 DataSet_01_279
PSG1 MSX1 siRNA Tooth Dental Pulp Cells 3.45658 1.78935 0.00036 0.00241 DataSet_01_281
PSG1 POSTN shRNA Brain GSC272 4.52757 2.17874 0.06497 0.53976 DataSet_01_293
PSG1 TFAP4 siRNA Brain BE(2)-C 0.18357 -2.44563 0.32527 0.51625 DataSet_01_295
PSG1 SOX7 siRNA Umbilical_vein HUVEC 4.96876 2.31289 0.29437 0.89788 DataSet_01_299
PSG1 SOX17 siRNA Umbilical_vein HUVEC 3.89936 1.96324 0.20746 0.99998 DataSet_01_300
PSG1 PTEN shRNA Skin A431 0.63674 -0.65121 0.33966 0.53841 DataSet_01_301
PSG1 TFAP2C siRNA Lung NCI-H292 1.67455 0.74377 - - DataSet_01_312
PSG1 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 2.20439 1.14038 0.02495 0.28042 DataSet_01_313
PSG1 KLF4 siRNA Embryo HCE 2.45663 1.29668 0.38218 0.77451 DataSet_01_341
PSG1 KLF7 siRNA Embryo HCE 12.4028 3.63259 0.05846 0.99985 DataSet_01_342
PSG1 ARID1A shRNA Uterus iEEC16 0.62895 -0.66897 - - DataSet_01_345
PSG1 GATA3 siRNA Oral_cavity OEC-M1 0.48353 -1.04831 0.13855 0.99787 DataSet_01_347
PSG1 ELK1 siRNA Mammary_gland MDA-MB-231 1.80305 0.85044 - - DataSet_01_354
PSG1 NFYA siRNA Mammary_gland MDA-MB-231 1.76983 0.82361 - - DataSet_01_355
PSG1 RBFOX2 shRNA Liver HepG2 0.5 -1 0.75526 0.9113 DataSet_02_101
PSG1 FIP1L1 shRNA Liver HepG2 3.4 1.76553 0.54917 0.64077 DataSet_02_103
PSG1 ZNF622 shRNA Liver HepG2 1.83333 0.87447 0.10914 0.16504 DataSet_02_108
PSG1 HNRNPUL1 shRNA Liver HepG2 0.5 -1 1 1 DataSet_02_109
PSG1 GTF2F1 shRNA Liver HepG2 5.66667 2.5025 0.30615 0.62841 DataSet_02_110
PSG1 RBM39 shRNA Liver HepG2 1.66667 0.73697 0.30605 0.55397 DataSet_02_111
PSG1 XRCC5 shRNA Liver HepG2 3.66667 1.87447 0.19926 0.39704 DataSet_02_114
PSG1 TARDBP shRNA Liver HepG2 2.6 1.37851 0.14785 0.22821 DataSet_02_116
PSG1 RBM34 shRNA Liver HepG2 4.33333 2.11548 0.02959 0.40124 DataSet_02_121
PSG1 EWSR1 shRNA Liver HepG2 6.66667 2.73697 0.32822 0.45601 DataSet_02_122
PSG1 PCBP2 shRNA Liver HepG2 3.66667 1.87447 0.47238 0.63185 DataSet_02_123
PSG1 FUS shRNA Liver HepG2 9.66667 3.27302 0.27144 0.46211 DataSet_02_124
PSG1 HNRNPLL shRNA Liver HepG2 3.2 1.67807 0.02159 0.05377 DataSet_02_125
PSG1 SNRNP70 shRNA Liver HepG2 1.6 0.67807 0.60199 0.69704 DataSet_02_126
PSG1 SRSF3 shRNA Liver HepG2 93.8 6.55152 0.00322 0.06874 DataSet_02_127
PSG1 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.23077 -2.11548 0.03464 0.22383 DataSet_02_144
PSG1 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 5.5 2.45943 0.03697 1 DataSet_02_187
PSG1 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.25 2.08746 0.87037 1 DataSet_02_188
PSG1 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 5.125 2.35755 0.752 1 DataSet_02_195
PSG1 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.375 -1.41504 0.12209 1 DataSet_02_197
PSG1 ATF4 siRNA Skin A375 0.648271 -0.62533 0.199521265549432 0.775512819201899 DataSet_03_018
PSG1 CASP8AP2 siRNA Bone_marrow hTERT-RPE1 1.56874 0.649609 0.000518040948429151 0.047322501013015 DataSet_03_030
PSG1 CEBPB siRNA Embryo hESC 0.362205 -1.46512 0.389453583150419 0.730909895508743 DataSet_03_049
PSG1 ESR1 siRNA Mammary_gland MCF7 0.575926 -0.796045 0.000279213178526173 0.0078880471999592 DataSet_03_071
PSG1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 0.420547 -1.24966 - - DataSet_03_096
PSG1 GATA2 siRNA Uterus Decidual stromal cells 0.545301 -0.874875 0.672526450870628 0.966690257414943 DataSet_03_100
PSG1 GATA2 siRNA Lymph Lymphatic endothelial cells 0.166884 -2.58308 0.00236770968401891 0.0074349474923569 DataSet_03_101
PSG1 GATA3 siRNA Mammary_gland MCF7 0.423738 -1.23876 2.93288525458027e-06 0.00275001589559874 DataSet_03_103
PSG1 HES6 siRNA Brain A172 1.54491 0.627519 0.0222720554309944 0.999995680871491 DataSet_03_116
PSG1 HINFP siRNA Bone_marrow hTERT-RPE1 1.91307 0.935888 0.00344827975856441 0.112434879815633 DataSet_03_122
PSG1 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 0.564138 -0.825881 0.0617684672401585 0.875866997056734 DataSet_03_134
PSG1 KLF5 siRNA Colon SW480 0.66363 -0.591549 0.126467854816552 0.501289176107192 DataSet_03_148
PSG1 MEF2D shRNA Liver HuH7 1.57533 0.65565 - - DataSet_03_162
PSG1 MTA2 siRNA Stomach SGC-7901 0.590443 -0.76013 - - DataSet_03_169
PSG1 MYB siRNA Cord_Blood CD34+ progenitor cells 1.93649 0.953448 - - DataSet_03_170
PSG1 NPAT siRNA Bone_marrow hTERT-RPE1 1.96319 0.973203 0.00163687079651569 0.064370420871611 DataSet_03_200
PSG1 SOX11 siRNA Lung_fibroblast NHLF 0.560703 -0.83469 0.0434534991215567 0.374450504859096 DataSet_03_237
PSG1 SOX11 siRNA Lung_fibroblast NHLF 0.514475 -0.958828 0.0102375797592597 0.201591575045647 DataSet_03_238
PSG1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.514493 -0.958777 - - DataSet_03_246
PSG1 SP1 siRNA Cervix HeLa 3.94883 1.98143 1.32955792884909e-08 2.71484620550128e-05 DataSet_03_249
PSG1 SP1 siRNA Ovary OVSAYO 0.52464 -0.930601 0.102579920035476 0.387732704762372 DataSet_03_251
PSG1 ZNF750 siRNA Skin Primary neonatal keratinocytes 0.435236 -1.20013 0.00491383507402766 0.0572707742346981 DataSet_03_294
PSG1 SMAD4 CRISPR Liver HepG2 1.68889 0.756074 0.0129554444831781 0.0988351091629826 DataSet_04_035
PSG1 APTX CRISPR Liver HepG2 0.4 -1.32193 0.747095871516915 0.989249243867186 DataSet_04_069
PSG1 CNOT7 CRISPR Liver HepG2 0.333333 -1.58496 0.095812527128746 0.20718220698045 DataSet_04_045
PSG1 PAN2 CRISPR Liver HepG2 1.68889 0.756074 0.0291932620632675 0.106294331481156 DataSet_04_066
PSG1 RIOK2 CRISPR Liver HepG2 0.526316 -0.925999 0.584690116278494 1 DataSet_04_070
PSG1 SEPT11 CRISPR Liver HepG2 4.25 2.08746 0.119458731351392 0.342690999557709 DataSet_04_068
PSG1 CCAR1 shRNA Liver HepG2 0.625 -0.678072 0.740407203065285 0.850065675161062 DataSet_04_054
PSG1 DDX1 shRNA Liver HepG2 0.5 -1 0.73274408055381 0.876208510923444 DataSet_04_057
PSG1 NPM1 shRNA Liver HepG2 0.333333 -1.58496 0.551108580671184 0.882518904448156 DataSet_04_058
PSG1 PRPF6 shRNA Liver HepG2 7 2.80735 0.207175253037895 0.410527484521746 DataSet_04_056
PSG1 UBE2L3 shRNA Liver HepG2 5 2.32193 0.0753682182187862 0.162836826174746 DataSet_04_055
PSG1 YBX3 shRNA Liver HepG2 4.25 2.08746 0.365878319267718 0.560810157144242 DataSet_02_98
PSG1 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.419355 -1.25376 0.29257707479412 0.469213097723776 DataSet_02_34
PSG1 HMGA1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 5.4 2.43296 0.306066862545054 0.682209368233739 DataSet_02_75
PSG1 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.32258 1.7323 0.178005095552677 0.665377916225149 DataSet_02_45
PSG1 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.516129 -0.954196 0.325507889288847 0.505766759483767 DataSet_02_35
PSG1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 4.8871 2.28898 0.0956759664158458 0.415089980903254 DataSet_02_32
PSG1 EZH2 shRNA Colon SW480 3.85976 1.94851 - - DataSet_03_298
PSG1 AEBP1 siRNA Umbilical_vein HUVEC 1.74624 0.804249 2.833177e-01 0.843077521 DataSet_03_300
PSG1 ELF3 CRISPR Bile_duct HBDEC2 0.0844351 -3.56601 3.294743e-07 7.162953e-05 DataSet_03_304
PSG1 ELF3 knockdown Bile_duct HBDEC2 0.635037 -0.655089 3.727869e-03 4.112969e-02 DataSet_03_305
PSG1 SNAI2 shRNA Pancreas KLM1 0.245628 -2.02545 5.670389e-02 0.32247027 DataSet_03_307
PSG1 INO80 siRNA Muscle RD 4.93745 2.30377 - - DataSet_03_344
PSG1 AEBP1 siRNA Central_nervous_system U87MG 1.79838 0.846699 1.505763e-01 0.9999434 DataSet_03_338
PSG1 TET1 CRISPR Mammary_gland MDA-MB-231 11.4361 3.51552 7.863373e-03 5.175436e-02 DataSet_03_347
PSG1 TET1 CRISPR Mammary_gland Hs578T 2.2067 1.14189 4.155072e-02 1.270369e-01 DataSet_03_355
PSG1 NCOA3 siRNA Mammary_gland MDA-MB-231 0.581643 -0.781795 7.505207e-02 0.5496174 DataSet_03_361
PSG1 EP300 shRNA Mammary_gland MCF10AT 2 1 3.173779e-01 0.462324270 DataSet_03_364
PSG1 BHLHE40 shRNA Cervix HeLaS3 1.77444 0.827361 9.662454e-01 0.99680991 DataSet_03_372
PSG1 GLI1 siRNA Skeletal_muscle RMS13 6.46764 2.69324 8.180746e-03 0.067525088 DataSet_03_375
PSG1 SMARCA2 shRNA Lung NCI-H1944 2.83333 1.5025 2.505772e-02 3.058537e-01 DataSet_03_377
PSG1 EZH2 CRISPR Ovary SKOV3 0.185844 -2.42783 1.225939e-03 0.0236751531 DataSet_03_378
PSG1 ZBTB7A siRNA Stomach BGC823 0.361051 -1.46973 - - DataSet_03_380
PSG1 TCF19 CRISPR Oral_squamous CAL27 0.428256 -1.22345 7.212176e-01 0.8780967636 DataSet_03_383
PSG1 NFKBIA shRNA Bone_marrow U2OS 0.0078219 -6.99826 7.419418e-01 0.89034931 DataSet_03_389
PSG1 ILF2 siRNA Stomach SGC-7901 4.5 2.16992 0.5813124904 0.66041517 DataSet_03_393
PSG1 JAZF1 siRNA Cervix HeLa Kyoto 2.08523 1.0602 6.830758e-02 0.701047696 DataSet_03_396
PSG1 HMGA1 shRNA Bile_duct HUCCT1 5.75 2.52356 2.076577e-02 0.172014844 DataSet_03_400
PSG1 EHF shRNA Stomach MKN7 0.0957742 -3.38422 - - DataSet_03_402
PSG1 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 5 2.32193 4.080278e-01 0.5747889 DataSet_03_403
PSG1 SIRT1 siRNA Pancreas PANC1 4.66667 2.22239 3.905217e-01 0.558164461 DataSet_03_410
PSG1 FOXK2 shRNA Ovary OVCAR-5 0.318681 -1.64981 1.418370e-01 0.35156971 DataSet_03_419
PSG1 SUFU shRNA Mammary_gland HCC1954 cells 0.285714 -1.80735 0.6156198225 0.8451172 DataSet_03_437
PSG1 CIC knockout Brain Immortalized Astrocyte Cells 0.370526 -1.43235 8.820890e-02 4.960821e-01 DataSet_03_438
PSG1 HMG20A siRNA Mammary_gland MDA-MB-231 5.97727 2.57949 0.0293772991 0.2104640 DataSet_03_442
PSG1 PHF14 siRNA Mammary_gland MDA-MB-231 0.409091 -1.28951 0.1669004740 0.5994811 DataSet_03_443
PSG1 PURA siRNA Cervix HeLa 2.70588 1.4361 3.595044e-02 0.172139304 DataSet_03_444
PSG1 FOSL1 siRNA Prostate MSKPCa3 0.375 -1.41504 0.4514701572 0.6605188 DataSet_03_445
PSG1 RELB CRISPR Colon SW480 1.87267 0.9051 2.806901e-01 5.110708e-01 DataSet_03_449
PSG1 CBX2 siRNA Mammary_gland MCF7 37.4163 5.2256 5.097630e-03 0.0181654158 DataSet_03_451
PSG1 OGT siRNA Embryo BeWo cells 0.0275229 -5.18322 2.853350e-01 0.66237450 DataSet_03_453
PSG1 SREBF2 siRNA Umbilical_vein HUVEC 0.00195933 -8.99543 5.718784e-02 3.844473e-01 DataSet_03_457
PSG1 ARID1A shRNA Bile_duct MMNK1 1.53602 0.619193 1.192010e-01 0.373074997 DataSet_03_458
PSG1 PARP1 knockout Embryo_kidney HEK293a 2.35897 1.23816 4.038990e-06 4.523547e-05 DataSet_03_464
PSG1 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.7168674 0.9477358 DataSet_04_072
Regulation Region
 
T(co)Fs that significantly regulate OGT by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PSG1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines