Gene Overview
| Target Gene: | Tnnt1 |
| NCBI Official Symbol: | Tnnt1 |
| Entrez ID: | 21955 |
| Ensembl ID: | ENSMUSG00000064179 |
| Gene Full Name: | troponin T1, skeletal, slow |
| Strand: | - |
| Gene Locus: | 7 A1|7 2.6 cM |
| External Links: |
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Tnnt1 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Tnnt1
T(co)Fs
that Repress Tnnt1
The Intensity of the Gene Regulated by T(co)Fs:
Tnnt1-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Tnnt1 | Arid1a | knockout | Ovary | Ovary | 2.06911 | 1.04901 | 0.00376905832900145 | 0.94648870498129 | DataSet_11_005 |
| Tnnt1 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 0.185615 | -2.42962 | 0.0136294355592558 | 0.283448085285048 | DataSet_11_014 |
| Tnnt1 | Bhlha9 | knockout | Limb | Whole limb bud | 6.81069 | 2.7678 | - | - | DataSet_11_016 |
| Tnnt1 | Dmrt1 | knockout | Testis | Testes | 1.57149 | 0.652129 | 0.00742680555850735 | 0.117947453360644 | DataSet_11_029 |
| Tnnt1 | Dmrt1 | knockout | Testis | Testes | 1.57149 | 0.652129 | 0.00742680555850735 | 0.117947453360644 | DataSet_11_032 |
| Tnnt1 | Elf5 | knockout | Mammary_gland | Mammary gland | 4.95455 | 2.30875 | 0.240765105137921 | 0.5233947223211 | DataSet_11_035 |
| Tnnt1 | En2 | knockout | Hippocampus | Hippocampus | 2.32624 | 1.218 | 0.0492784641028494 | 0.246855082891984 | DataSet_11_037 |
| Tnnt1 | Foxp1 | knockout | Eye | Lens | 0.558674 | -0.839923 | - | - | DataSet_11_044 |
| Tnnt1 | Hoxc13 | knockout | Skin | Skin | 2.03872 | 1.02767 | 0.0625261456799483 | 0.36852194974521 | DataSet_11_057 |
| Tnnt1 | Hsf4 | knockout | Eye | Lens | 0.116273 | -3.10441 | 0.0259860851552917 | 0.987999303842427 | DataSet_11_058 |
| Tnnt1 | Irf6 | knockout | Skin | Skin | 0.544623 | -0.87667 | 0.000713245357957933 | 0.0399822215389338 | DataSet_11_062 |
| Tnnt1 | Irf8 | knockout | Lymph | Splenic CD11b+Gr-1 cells | 4.05616 | 2.02011 | 2.53772571297228e-05 | 0.00256293039374249 | DataSet_11_063 |
| Tnnt1 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 0.453831 | -1.13977 | 0.706163024859136 | 0.943205536823301 | DataSet_11_064 |
| Tnnt1 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.586577 | -0.769608 | 0.0165558438106432 | 0.0561667054557507 | DataSet_11_066 |
| Tnnt1 | Lhx8 | knockout | Ovary | Ovary | 1.81219 | 0.857731 | 0.0128948554033477 | 0.0603370040102238 | DataSet_11_070 |
| Tnnt1 | Mafg | knockout | Embryo | Whole embryo | 0.632075 | -0.661831 | 0.468138190218704 | 1 | DataSet_11_073 |
| Tnnt1 | Mbd1 | siRNA | Adipose_tissue | 3T3-L1 cells | 2.44444 | 1.28951 | - | - | DataSet_11_074 |
| Tnnt1 | Mbd2 | knockout | Lymph | GFP+ BM leukemia cells | 3.51508 | 1.81356 | 3.9748576466228e-05 | 0.000920117438042449 | DataSet_11_076 |
| Tnnt1 | Mef2a | shRNA | Muscle | C2C12 | 0.386897 | -1.36998 | 1.74650130838046e-07 | 1.64980477252622e-05 | DataSet_11_077 |
| Tnnt1 | Meis1 | knockout | Hematopoietic | KSL hematopoietic cells | 0.542636 | -0.881944 | 0.178955649266667 | 0.995635220774426 | DataSet_11_081 |
| Tnnt1 | Meis1 | knockout | Bone_marrow | Immortalized myeloid cell | 0.624901 | -0.6783 | 4.97481225937379e-07 | 1.45036097435335e-05 | DataSet_11_082 |
| Tnnt1 | Npas4 | RNAi | Brain | Hippocampal Neurons | 1.55421 | 0.63618 | 0.514227647442314 | 0.749198906687344 | DataSet_11_093 |
| Tnnt1 | Otx2 | knockout | Eye | Retina | 4.20264 | 2.0713 | 0.690624007842815 | 0.999923528647439 | DataSet_11_097 |
| Tnnt1 | Pax6 | knockout | Embryo | Surface ectoderm | 0.621593 | -0.685957 | 0.253918127225012 | 0.795631034444807 | DataSet_11_101 |
| Tnnt1 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 0.208412 | -2.26249 | 0.975881102603482 | 0.999962577291099 | DataSet_11_105 |
| Tnnt1 | Runx1 | knockout | Mammary_gland | Luminal epithelial cells | 0.626876 | -0.673748 | 0.114814641717793 | 0.999784944667092 | DataSet_11_117 |
| Tnnt1 | Sall1 | knockout | Kidney | Kidney | 1.61133 | 0.688252 | 0.137325575613731 | 0.486682203519863 | DataSet_11_121 |
| Tnnt1 | Smad4 | siRNA | Brain | bEnd3 | 10.542 | 3.39808 | - | - | DataSet_11_127 |
| Tnnt1 | Smad4 | knockout | Aorta | Aortic arteries | 0.586192 | -0.770554 | 0.151612123393763 | 0.557700205149013 | DataSet_11_128 |
| Tnnt1 | Snai1 | knockout | Embryo | Embryoid body | 4.30872 | 2.10726 | - | - | DataSet_11_129 |
| Tnnt1 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 2.9954 | 1.58275 | 0.00235277624134581 | 0.999994003527217 | DataSet_11_132 |
| Tnnt1 | Sox2 | siRNA | Embryo | NG4 | 3.33914 | 1.73948 | 0.000517104635139719 | 0.02605858280481 | DataSet_11_141 |
| Tnnt1 | Sox9 | knockout | Lung | Trachea | 2.10504 | 1.07385 | 0.0938468841414907 | 0.390721800720818 | DataSet_11_144 |
| Tnnt1 | Spdef | knockout | Colon | Colon | 0.532549 | -0.909013 | 0.206564332860571 | 0.997507742354799 | DataSet_11_146 |
| Tnnt1 | Spdef | knockout | Stomach | Stomach | 0.623977 | -0.680435 | 0.326806122372639 | 0.906520586026976 | DataSet_11_147 |
| Tnnt1 | Srf | knockout | Aorta | Aorta | 0.486327 | -1.04 | 0.0452387144202998 | 0.993526315825099 | DataSet_11_148 |
| Tnnt1 | Stat3 | knockout | Lung | Lung typeII cells | 0.354603 | -1.49572 | 0.0278056019948978 | 0.643261091591976 | DataSet_11_151 |
| Tnnt1 | Thap1 | knockout | Brain | Cerebellum | 0.601513 | -0.733331 | 0.000379376320225359 | 0.00443550923533607 | DataSet_11_164 |
| Tnnt1 | Thap1 | knockout | Brain | Cortex | 0.579085 | -0.788152 | 5.05319020553411e-05 | 0.00120956151287025 | DataSet_11_165 |
| Tnnt1 | Vdr | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.00268 | 1.00193 | 0.41056919688542 | 0.999827445128963 | DataSet_11_174 |
| Tnnt1 | Vdr | knockout | Skin | Skin | 1.6103 | 0.687333 | - | - | DataSet_11_176 |
| Tnnt1 | Wt1 | siRNA | Embryo_kidney | LB-22 | 1.58152 | 0.661308 | 0.307328633910759 | 0.556782363865117 | DataSet_11_179 |
| Tnnt1 | Yy1 | knockout | White_adipose_tissue | Visceral white adipose tissue | 0.372632 | -1.42418 | 0.0475107376468815 | 0.172385145810637 | DataSet_11_185 |
| Tnnt1 | Cpeb1 | siRNA | Neuron | Neuro-2a | 0.507695 | -0.977966 | - | - | DataSet_11_189 |
| Tnnt1 | Mapk9 | knockout | Hip | Mouse Hip Cartilage | 0.152521 | -2.71292 | 5.641824e-08 | 3.040426e-06 | DataSet_11_236 |
| Tnnt1 | Hipk2 | knockout | Heart | cardiac tissue | 1.57823 | 0.658305 | 5.563769e-04 | 4.866237e-02 | DataSet_11_238 |
| Tnnt1 | Tet1 | knockout | Embryo | ES cells | 0.611727 | -0.70904 | 5.843253e-03 | 0.14546200 | DataSet_11_216 |
| Tnnt1 | Dnmt1 | knockout | Embryo | Embryonic fibroblasts | 2.80157 | 1.48624 | 5.599756e-02 | 1.701575e-01 | DataSet_11_192 |
| Tnnt1 | Dnmt1 | shRNA | Embryo | Embryonic fibroblasts | 3.79562 | 1.92434 | - | - | DataSet_11_196 |
| Tnnt1 | Tet1 | knockout | Hippocampus | Hippocampus | 0.526068 | -0.92668 | 2.506876e-01 | 0.53873022 | DataSet_11_219 |
| Tnnt1 | Ezh2 | knockdown | Brain | Brain | 4.88235 | 2.28758 | 1.414546e-05 | 0.0033631494 | DataSet_11_221 |
| Tnnt1 | Dnmt1 | knockout | Liver | Liver | 1.57496 | 0.655315 | 1.879308e-03 | 3.395121e-02 | DataSet_11_232 |
| Tnnt1 | Dnmt3b | knockout | Heart | Cardiac ventricle | 2.78931 | 1.47991 | 2.632002e-11 | 2.708243e-07 | DataSet_11_205 |
| Tnnt1 | Smarca4 | shRNA | Embryo | ES cells | 0.402188 | -1.31406 | - | - | DataSet_11_224 |
| Tnnt1 | Smarca4 | shRNA | Embryo | ES cells | 0.402188 | -1.31406 | - | - | DataSet_11_225 |
| Tnnt1 | Ncl | siRNA | Embryo | ES cells | 0.635451 | -0.654146 | 1.257035e-01 | 0.4897743727 | DataSet_11_240 |
| Tnnt1 | Dnmt3a | siRNA | Embryo | iPSC | 0.181384 | -2.46288 | - | - | DataSet_11_241 |
| Tnnt1 | Lin28a | knockout | Heart | Heart | 1.55231 | 0.634417 | 0.0402869913 | 0.8777652 | DataSet_11_243 |
| Tnnt1 | Twist1 | knockout | Bone_marrow | stromal cells | 2.84751 | 1.5097 | - | - | DataSet_11_244 |
| Tnnt1 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.451282 | -1.1479 | 9.766699e-03 | 0.1021893398 | DataSet_11_245 |
| Tnnt1 | Fubp1 | shRNA | Brain | brain neural progenitors | 0.617254 | -0.696064 | 0.5702424615 | 1 | DataSet_11_246 |
| Tnnt1 | Ezh2 | knockout | Calvaria | calvaria | 0.611111 | -0.710493 | 1.372985e-02 | 0.46193852 | DataSet_11_247 |
| Tnnt1 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 26.3333 | 4.71882 | 4.375493e-04 | 4.789112e-03 | DataSet_11_250 |
| Tnnt1 | Kdm2a | CRISPR | Embryo | ES cells | 0.660714 | -0.597902 | 0.1967602807 | 1.0000000 | DataSet_11_251 |
| Tnnt1 | Mecp2 | knockout | Adipose_tissue | brown adipose tissue | 0.176361 | -2.5034 | 2.429855e-02 | 0.214451455 | DataSet_11_253 |
| Tnnt1 | Eed | knockout | Spinal_cord | spinal cord | 0.404236 | -1.30673 | 4.016470e-01 | 9.999790e-01 | DataSet_11_261 |
| Tnnt1 | Fubp1 | shRNA | Bone_marrow | BM cells | 1.79661 | 0.845277 | 1.097649e-01 | 0.666168912 | DataSet_11_262 |
| Tnnt1 | Bcl3 | knockout | Bone | Osteoblast | 1.97761 | 0.983759 | 8.575901e-03 | 4.324551e-01 | DataSet_11_263 |
| Tnnt1 | Mef2d | CRISPR | Heart | Cardiac ventricle | 1.77594 | 0.828585 | 5.645328e-04 | 0.0287697542 | DataSet_11_270 |
| Tnnt1 | Kat6b | shRNA | Bone_marrow | LT-HSCs | 1.74194 | 0.800691 | 1.223534e-01 | 0.6038131 | DataSet_11_271 |
| Tnnt1 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.45129 | -1.14787 | 7.298390e-02 | 0.80495832 | DataSet_11_272 |
| Tnnt1 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.00427801 | -7.86885 | 9.700071e-10 | 3.290949e-07 | DataSet_11_275 |
| Tnnt1 | Usp7 | knockout | Embryo | ES cells | 0.4329 | -1.20789 | 5.639582e-03 | 0.2150674 | DataSet_11_279 |
| Tnnt1 | Pdx1 | CRISPR | Liver | Liver | 0.537906 | -0.894574 | 1.994465e-02 | 0.320198855 | DataSet_11_286 |
| Tnnt1 | Med19 | knockout | White_adipose_tissue | Gonadal white adipose tissue | 1.84854 | 0.886387 | 4.715020e-02 | 2.745844e-01 | DataSet_11_289 |
| Tnnt1 | Tfap2a | knockout | Brain | Brain | 0.46169 | -1.11501 | 0.1766419540 | 0.9599640 | DataSet_11_295 |
| Tnnt1 | Ssrp1 | CRISPR | Embryo | ES cells | 1.54167 | 0.624491 | 1.966574e-02 | 0.19243613 | DataSet_11_296 |
| Tnnt1 | Phf8 | knockout | prostate | Prostate | 0.25 | -2 | 0.2228261232 | 0.4747197 | DataSet_11_298 |
| Tnnt1 | Arid2 | knockout | Muscle | LSK | 1.86752 | 0.901125 | 7.892240e-02 | 9.026354e-01 | DataSet_11_301 |
| Tnnt1 | Dnmt1 | knockout | Skin | Keratinocytes | 2.04136 | 1.02953 | 4.215938e-02 | 0.2897145158 | DataSet_11_303 |
| Tnnt1 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.664794 | -0.589021 | - | - | DataSet_11_305 |
| Tnnt1 | Jmjd6 | knockout | Bone_marrow | Lin-Sca1+Kit+ (LSK) haematopoietic stem and progenitor cells | 2.7931 | 1.48187 | - | - | DataSet_11_306 |
| Tnnt1 | Myc | CRISPR | Skeletal_muscle | quiescent muscle stem cell | 3.78569 | 1.92056 | 1.166781e-02 | 0.26689145 | DataSet_11_310 |
| Tnnt1 | Suz12 | knockout | Lung | Alveolar macrophage | 0.333333 | -1.58496 | 3.669102e-01 | 0.7502039691 | DataSet_11_311 |
| Tnnt1 | Irf7 | knockout | Bone_marrow | c-kit+ leukemic cells | 6.25933 | 2.64601 | - | - | DataSet_11_313 |
| Tnnt1 | Actl6a | knockout | Nerve | sciatic nerve | 1.92524 | 0.945039 | 5.514111e-01 | 0.744604172 | DataSet_11_314 |
| Tnnt1 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 0.316691 | -1.65885 | 9.651665e-02 | 0.3952056088 | DataSet_11_317 |
| Tnnt1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.333333 | -1.58496 | 4.792688e-03 | 2.144112e-01 | DataSet_11_319 |
| Tnnt1 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.41791 | -1.25873 | 2.329334e-02 | 1.292585e-01 | DataSet_11_320 |
| Tnnt1 | Gata2 | knockout | Brain | Pituitary gland | 1.57143 | 0.652077 | 0.463221596 | 1.0000000 | DataSet_11_322 |
| Tnnt1 | Setdb1 | shRNA | Neuron | NE-4C | 0.0897163 | -3.47849 | - | - | DataSet_11_323 |
| Tnnt1 | Tet1 | siRNA | Embryo | Embryonic fibroblasts | 0.392192 | -1.35037 | 5.898746e-02 | 0.9609895 | DataSet_11_327 |
| Tnnt1 | Kdm5b | siRNA | Embryo | ES cells | 0.544367 | -0.877348 | 0.0206935776 | 0.8933528 | DataSet_11_331 |
| Tnnt1 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 3.98765 | 1.99554 | 1.119294e-03 | 2.624616e-02 | DataSet_11_332 |
| Tnnt1 | Ezh2 | knockout | Eye | Retina | 0.456693 | -1.1307 | 1.690628e-04 | 6.323661e-03 | DataSet_11_333 |
| Tnnt1 | Ezh2 | knockout | Eye | Retina | 0.0530234 | -4.23723 | 0.5244874297 | 1.0000000 | DataSet_11_334 |
| Tnnt1 | Atrx | knockout | Embryo | ES cells | 1.93878 | 0.955146 | - | - | DataSet_11_335 |
| Tnnt1 | Dnmt3a | knockout | Peritoneum | peritoneal macrophages | 2.10343 | 1.07275 | - | - | DataSet_11_336 |
| Tnnt1 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 1.92647 | 0.94596 | 1.384550e-01 | 0.69832724 | DataSet_11_337 |
| Tnnt1 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 2.74632 | 1.4575 | 1.169599e-02 | 0.34658630 | DataSet_11_338 |
| Tnnt1 | Gtf2ird1 | knockout | Lip | Lip | 0.434295 | -1.20325 | 1.105889e-02 | 2.150348e-01 | DataSet_11_339 |
| Tnnt1 | Dnmt1 | siRNA | Heart | embryonic cardiomyocytes | 0.606618 | -0.721141 | 3.817409e-01 | 0.473953886 | DataSet_11_340 |
| Tnnt1 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 2.38095 | 1.25154 | 0.0956692095 | 0.1743267 | DataSet_11_341 |
| Tnnt1 | Dnmt1 | knockout | Kidney | kidney Cap Mesenchyme | 1.85466 | 0.891158 | 2.162999e-04 | 1.254926e-02 | DataSet_11_344 |
| Tnnt1 | Setdb1 | shRNA | Embryo | ES cells | 1.60635 | 0.683789 | 1.093631e-01 | 1.000000e+00 | DataSet_11_346 |
Regulation Region
Expression Atlas of Tnnt1