Gene Overview
Target Gene: CD274
NCBI Official Symbol: CD274
Entrez ID: 29126
Ensembl ID: ENSG00000120217
Gene Full Name: CD274 molecule
Strand: +
Gene Locus: 9p24.1
External Links:

CD274 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate CD274   
T(co)Fs that Repress CD274
The Intensity of the Gene Regulated by T(co)Fs:
CD274-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
CD274 FOXO1 shRNA Bone EWS-FLI1 1.61122 0.68815 0.06055 0.46071 DataSet_01_106
CD274 HOXA1 siRNA Lung_fibroblast IMR-90 0.37995 -1.39612 0.00714 0.09035 DataSet_01_110
CD274 GABPA siRNA Lung A549 1.64578 0.71877 7.24491e-07 8.55453e-06 DataSet_01_113
CD274 TCF3 shRNA Mammary_gland MDA-MB468 2.37188 1.24603 0.01005 0.06059 DataSet_01_116
CD274 ID1 siRNA Lung A549 4.45552 2.15559 0.00028 0.08908 DataSet_01_117
CD274 ZIC2 siRNA Pancreas PANC1 3.73232 1.90007 - - DataSet_01_121
CD274 FOXM1 siRNA Central_nervous_system U87 17.9102 4.16271 - - DataSet_01_122
CD274 ZNF43 siRNA Gastrointestinal_tissue GIST-T1 0.56151 -0.83261 0.00012 0.00747 DataSet_01_125
CD274 ZNF254 siRNA Gastrointestinal_tissue GIST-T1 0.64349 -0.63602 0.00086 0.01208 DataSet_01_127
CD274 GLI2 siRNA Bone_marrow U2OS 0.65547 -0.60939 - - DataSet_01_143
CD274 MYBL2 shRNA Bone_marrow CD34+ BM cells 0.48343 -1.04863 0.0036 0.16422 DataSet_01_148
CD274 LIN28B siRNA Embryo_kidney HEK293 2.99597 1.58302 0.00116 0.01985 DataSet_01_153
CD274 HSF1 shRNA Skin A375 1.73672 0.79637 0.0038 0.0328 DataSet_01_155
CD274 ELK1 siRNA Peripheral_blood CD4+ T cells 286.648 8.16313 0.04534 0.14591 DataSet_01_162
CD274 JUN siRNA Peripheral_blood CD4+ T cells 1.91505 0.93738 0.03191 0.14662 DataSet_01_164
CD274 MAF siRNA Peripheral_blood CD4+ T cells 1.70321 0.76825 0.0587 0.29679 DataSet_01_165
CD274 NFATC3 siRNA Peripheral_blood CD4+ T cells 425.965 8.73459 0.06539 0.26713 DataSet_01_166
CD274 FOSL1 siRNA Mammary_gland BT549 1.9092 0.93296 1.22231e-06 0.00021 DataSet_01_171
CD274 ESRRG siRNA Placenta_tissue Trophoblast cells 3.82118 1.93402 0.00013 0.01085 DataSet_01_173
CD274 TCF4 siRNA Autonomic_ganglia SH-SY5Y 1.99951 0.99964 0.00051 0.02401 DataSet_01_185
CD274 TP63 siRNA Head_and_neck SCC-1 0.63613 -0.6526 - - DataSet_01_199
CD274 HIC1 shRNA Mammary_gland HBL100 0.6344 -0.65654 - - DataSet_01_205
CD274 EGR3 shRNA Prostate M12 0.34688 -1.5275 0.01024 0.11734 DataSet_01_212
CD274 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.98117 0.98635 0.00027 0.00791 DataSet_01_217
CD274 ESR2 siRNA Mammary_gland BT549 2.7384 1.45333 1.62805e-06 8.4663e-05 DataSet_01_229
CD274 JUN shRNA Soft_tissue LP6 0.56501 -0.82366 0.03902 0.45955 DataSet_01_230
CD274 FOXA1 siRNA Prostate LNCaP 4.43965 2.15044 0.00283 0.09834 DataSet_01_233
CD274 FOXP1 siRNA Prostate LNCaP 2.72389 1.44567 0.09587 0.49779 DataSet_01_234
CD274 MYC shRNA Soft_tissue HT1080 1.59849 0.67671 - - DataSet_01_237
CD274 FOXO3 siRNA Pancreas PANC1 0.47483 -1.07452 - - DataSet_01_267
CD274 STAT5 shRNA Prostate CWR22Pc 1.81914 0.86326 0.04045 0.13052 DataSet_01_279
CD274 ESRRA shRNA Embryo_kidney 293T 0.61444 -0.70266 0.24297 0.79327 DataSet_01_280
CD274 MSX1 siRNA Tooth Dental Pulp Cells 3.83395 1.93883 0.00101 0.00511 DataSet_01_281
CD274 AHR siRNA Haematopoietic_and_lymphoid_tissue THP-1 1.7277 0.78886 0.00021 0.00302 DataSet_01_283
CD274 NFYA shRNA Colon HCT1163 0.60518 -0.72457 0.00204 0.03169 DataSet_01_287
CD274 POSTN shRNA Brain GSC272 1.61535 0.69185 0.34364 0.67544 DataSet_01_293
CD274 TFAP4 siRNA Brain BE(2)-C 0.16054 -2.63901 0.30932 0.51625 DataSet_01_295
CD274 ARID1B shRNA Liver IRM90 0.45056 -1.15021 4.7229e-05 0.00208 DataSet_01_298
CD274 TFAP2C siRNA Lung NCI-H292 2.44106 1.28751 - - DataSet_01_312
CD274 ELK3 shRNA Mammary_gland MDA-MB-231 0.43439 -1.20294 3.49368e-05 0.00029 DataSet_01_318
CD274 TP63 shRNA Immortalized_keratinocyte HaCaT 2.021 1.01507 2.1275e-08 2.97305e-06 DataSet_01_325
CD274 TP63 shRNA Immortalized_keratinocyte HaCaT 2.021 1.01507 2.1275e-08 2.97305e-06 DataSet_01_328
CD274 STAT3 siRNA Liver LX-2 1.80832 0.85465 4.87779e-06 1e-04 DataSet_01_334
CD274 REST siRNA Skin NHEK 1.54383 0.62652 0.00778 0.08935 DataSet_01_337
CD274 KLF4 siRNA Embryo HCE 1.54226 0.62504 0.02426 0.3285 DataSet_01_339
CD274 KLF7 siRNA Embryo HCE 0.42333 -1.24016 0.0859 0.6419 DataSet_01_340
CD274 ETV4 shRNA Prostate PC3 0.3298 -1.60034 - - DataSet_01_356
CD274 SOX17 siRNA Umbilical_vein HUVEC 1.51926 0.60337 - - DataSet_01_360
CD274 GTF2B siRNA Cervix HeLa 0.58445 -0.77484 - - DataSet_01_362
CD274 RBM17 shRNA Liver HepG2 0.55102 -0.85982 0.27237 0.54132 DataSet_02_100
CD274 RBFOX2 shRNA Liver HepG2 0.28571 -1.80735 0.15182 0.65738 DataSet_02_101
CD274 SAFB2 shRNA Liver HepG2 2 1 0.4178 0.51854 DataSet_02_102
CD274 FIP1L1 shRNA Liver HepG2 6.06667 2.6009 0.19523 0.29108 DataSet_02_103
CD274 U2AF2 shRNA Liver HepG2 2.53333 1.34104 0.01827 0.08829 DataSet_02_105
CD274 TAF15 shRNA Liver HepG2 8 3 0.0102 0.03053 DataSet_02_106
CD274 SSB shRNA Liver HepG2 1.76471 0.81943 0.70893 0.76157 DataSet_02_107
CD274 HNRNPUL1 shRNA Liver HepG2 2.53333 1.34104 0.27094 0.36629 DataSet_02_109
CD274 PCBP1 shRNA Liver HepG2 54 5.75489 0.00278 0.01784 DataSet_02_115
CD274 TARDBP shRNA Liver HepG2 1.70732 0.77173 0.3114 0.40711 DataSet_02_116
CD274 CEBPZ shRNA Liver HepG2 5.2 2.37851 0.04358 1 DataSet_02_118
CD274 RBM25 shRNA Liver HepG2 25 4.64386 0.17077 0.25964 DataSet_02_119
CD274 PTBP1 shRNA Liver HepG2 23 4.52356 0.00135 0.00775 DataSet_02_120
CD274 RBM34 shRNA Liver HepG2 1.95556 0.96758 0.38326 0.69328 DataSet_02_121
CD274 EWSR1 shRNA Liver HepG2 0.37931 -1.39855 0.17319 0.2916 DataSet_02_122
CD274 FUS shRNA Liver HepG2 1.8 0.848 0.72915 0.83814 DataSet_02_124
CD274 SNRNP70 shRNA Liver HepG2 1.90244 0.92785 0.29361 0.40923 DataSet_02_126
CD274 SRSF3 shRNA Liver HepG2 0.5122 -0.96523 0.5985 0.72791 DataSet_02_127
CD274 PRPF4 shRNA Liver HepG2 0.0625 -4 0.0234 0.08222 DataSet_02_128
CD274 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 3.76471 1.91254 0.02693 0.27905 DataSet_02_129
CD274 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 0.55556 -0.848 0.42999 0.83122 DataSet_02_130
CD274 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 5.76471 2.52725 0.01369 0.05358 DataSet_02_131
CD274 SRSF7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.23529 -2.08746 0.02712 0.24843 DataSet_02_133
CD274 SRSF9 shRNA Haematopoietic_and_lymphoid_tissue K562 0.29412 -1.76553 0.05739 0.1657 DataSet_02_134
CD274 PCBP2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.70588 0.77052 0.11284 0.25059 DataSet_02_135
CD274 HNRNPK shRNA Haematopoietic_and_lymphoid_tissue K562 2.88235 1.52725 0.12271 0.3221 DataSet_02_136
CD274 PCBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.64706 0.71989 0.33831 0.56835 DataSet_02_137
CD274 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.40351 -1.30933 0.04897 0.30736 DataSet_02_138
CD274 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.02985 -5.06609 0.00048 0.44546 DataSet_02_139
CD274 RBM34 shRNA Haematopoietic_and_lymphoid_tissue K562 3.82353 1.9349 0.23394 0.45214 DataSet_02_141
CD274 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.31579 1.72935 0.0931 0.24438 DataSet_02_142
CD274 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.56 -0.8365 0.31646 0.40285 DataSet_02_143
CD274 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16418 -2.60666 0.00462 0.2373 DataSet_02_148
CD274 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 20.5 4.35755 0.00277 0.19424 DataSet_02_149
CD274 ILF2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.98391 1 DataSet_02_152
CD274 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46269 -1.11189 0.57924 0.84882 DataSet_02_153
CD274 SRSF4 shRNA Haematopoietic_and_lymphoid_tissue K562 0.57143 -0.80735 0.0283 0.37594 DataSet_02_154
CD274 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.31579 -1.66297 0.85124 0.9247 DataSet_02_155
CD274 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46667 -1.09954 0.07583 0.51515 DataSet_02_156
CD274 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.27381 -1.86876 0.03086 0.828 DataSet_02_157
CD274 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.25806 -1.9542 0.05146 0.14642 DataSet_02_158
CD274 HNRNPL shRNA Haematopoietic_and_lymphoid_tissue K562 1.72 0.78241 0.3927 0.5739 DataSet_02_160
CD274 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.17857 -2.48543 0.00189 0.54364 DataSet_02_161
CD274 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59649 -0.74543 0.53197 0.84845 DataSet_02_162
CD274 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 16.8333 4.07325 0.84662 0.92132 DataSet_02_163
CD274 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.59459 -0.75002 0.60689 0.74184 DataSet_02_165
CD274 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.15789 -2.66297 0.64131 0.79867 DataSet_02_167
CD274 RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 5.23529 2.38827 0.03735 0.11947 DataSet_02_168
CD274 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 8 3 0.05965 0.12959 DataSet_02_169
CD274 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.32432 -1.62449 0.21232 0.41799 DataSet_02_171
CD274 ZFX siRNA Prostate C4-2B 0.56481 -0.82415 0.01039 0.03218 DataSet_02_172
CD274 MXI1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.08571 -3.54432 0.02021 1 DataSet_02_173
CD274 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 4.14286 2.05063 0.27785 1 DataSet_02_174
CD274 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 2.04545 1.03242 0.89472 1 DataSet_02_175
CD274 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.38182 -1.38904 0.01674 1 DataSet_02_176
CD274 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 4.4 2.1375 0.70224 1 DataSet_02_178
CD274 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 12.6 3.65535 0.30967 1 DataSet_02_179
CD274 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.33333 -1.58496 0.4029 1 DataSet_02_181
CD274 KAT2B siRNA Haematopoietic_and_lymphoid_tissue K562 2.22222 1.152 0.15778 1 DataSet_02_184
CD274 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.61538 -0.70044 0.65266 1 DataSet_02_186
CD274 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.61538 0.69188 0.85648 1 DataSet_02_187
CD274 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 3.74359 1.90442 0.60036 1 DataSet_02_190
CD274 LMNB2 siRNA Haematopoietic_and_lymphoid_tissue K562 1.95455 0.96683 0.8678 1 DataSet_02_191
CD274 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.25424 -1.97575 0.2797 1 DataSet_02_193
CD274 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.36364 -1.45943 0.1396 1 DataSet_02_194
CD274 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.27273 -1.87447 0.01908 1 DataSet_02_195
CD274 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.63636 -0.65208 0.13471 1 DataSet_02_197
CD274 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 1.87879 0.9098 0.88509 1 DataSet_02_198
CD274 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.27354 1 DataSet_02_201
CD274 BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.51429 1.33015 0.39405 1 DataSet_02_202
CD274 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 3.4 1.76553 0.7737 1 DataSet_02_203
CD274 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.90866 1 DataSet_02_204
CD274 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 0.27273 -1.87447 0.00538 1 DataSet_02_205
CD274 ZFX siRNA Mammary_gland MCF7 2 1 0.02669 0.1456 DataSet_02_206
CD274 ATF4 siRNA Skin A375 0.504238 -0.987824 0.123398344270645 0.775512819201899 DataSet_03_018
CD274 ATOH8 siRNA Umbilical_vein HUVEC 0.473811 -1.07762 0.177744077361233 0.885272532352317 DataSet_03_019
CD274 BCL6 siRNA Lymph Pfeiffer DLBCL 0.353586 -1.49987 0.00778341062744987 0.296394820167002 DataSet_03_026
CD274 CASP8AP2 siRNA Bone_marrow U2OS 1.61736 0.693642 0.0354436386019558 0.204825692731368 DataSet_03_031
CD274 FLI1 siRNA Haematopoietic_and_lymphoid_tissue THP-1 2.44749 1.2913 3.52255062144991e-05 0.0227343707243391 DataSet_03_078
CD274 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.06001 1.04265 - - DataSet_03_096
CD274 GATA2 siRNA Uterus Decidual stromal cells 0.291631 -1.77778 0.0240374116563223 0.520145941954223 DataSet_03_100
CD274 GATA6 siRNA Stomach AGS 2.05409 1.0385 0.0070011571121189 0.264589977771265 DataSet_03_108
CD274 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 2.08306 1.0587 0.0086457670434105 0.570137209822132 DataSet_03_134
CD274 KLF5 siRNA Stomach KatoIII 1.84391 0.88277 0.0415200770366957 0.411482695442542 DataSet_03_150
CD274 MAFB siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 0.62057 -0.688333 0.087944721589753 1 DataSet_03_155
CD274 MEF2D shRNA Liver HuH7 2.75501 1.46206 - - DataSet_03_162
CD274 MEF2D siRNA Liver HuH7 1.67757 0.746373 - - DataSet_03_163
CD274 MTA2 siRNA Stomach SGC-7901 0.375706 -1.41232 - - DataSet_03_169
CD274 MYC siRNA Colon HT29 3.62151 1.85659 - - DataSet_03_177
CD274 MYC siRNA Central_nervous_system DAOY M2.1 1.90174 0.927324 6.27529973751813e-07 5.71453388628912e-06 DataSet_03_178
CD274 NFKB1 siRNA Central_nervous_system U251 0.597495 -0.743 7.42231556253591e-05 0.00491869769946054 DataSet_03_197
CD274 NR2F2 siRNA Uterus Primary eutopic stromal cells 1.72459 0.786252 0.00325489595042387 0.704622161867156 DataSet_03_202
CD274 PRRX1 CRISPR Neuroblastoma 691-MES 1.54536 0.627945 0.108929465202009 0.89189998148014 DataSet_03_217
CD274 SOX11 siRNA Lung_fibroblast NHLF 0.48191 -1.05316 0.0339138634740861 0.354444130118142 DataSet_03_237
CD274 SOX11 siRNA Lung_fibroblast NHLF 0.398997 -1.32555 0.14143932491003 0.513654148181235 DataSet_03_238
CD274 SOX2 siRNA Embryo 2102Ep 1.56311 0.644423 0.000237395125455878 0.00673178552465078 DataSet_03_242
CD274 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 0.614458 -0.702614 - - DataSet_03_246
CD274 SRF siRNA Prostate LNCaP 1.63654 0.710648 0.0911075859836034 0.305549755997357 DataSet_03_254
CD274 STAT6 siRNA Umbilical_vein HUVEC 0.488885 -1.03243 0.0355626077749737 0.677432945084944 DataSet_03_264
CD274 TET2 siRNA Prostate LNCaP 1.5821 0.66184 - - DataSet_03_272
CD274 TFAP2C siRNA Mammary_gland MCF7 1.75574 0.812079 0.0162954979856786 0.301406987021975 DataSet_03_274
CD274 TWIST1 siRNA Bone_marrow MSCs 0.446429 -1.1635 - - DataSet_03_283
CD274 ZHX2 shRNA Kidney 786-O 1.907 0.931302 0.00407370708215697 0.0339700869133661 DataSet_03_287
CD274 ZNF750 siRNA Skin Primary neonatal keratinocytes 1.74654 0.804501 0.00289783685924459 0.0453415153084838 DataSet_03_294
CD274 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.16667 2.05889 0.0321424996754674 0.518730914089848 DataSet_04_001
CD274 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 5.57143 2.47805 0.0257367226268734 0.0914857874225667 DataSet_04_002
CD274 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.42857 1.28011 0.561211661965584 0.949615469538917 DataSet_04_003
CD274 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.66667 1.41504 0.507357130863749 0.601987984826434 DataSet_04_004
CD274 DDX59 CRISPR Haematopoietic_and_lymphoid_tissue K562 10.3333 3.36923 0.0153041628847402 0.518744806039141 DataSet_04_006
CD274 EIF2AK2 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.33333 1.73697 0.166402620094541 0.5358410772083 DataSet_04_008
CD274 ERN1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.878265538759842 0.972417608638779 DataSet_04_009
CD274 FUBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.1479610197101 0.259989846160101 DataSet_04_010
CD274 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 12.3333 3.62449 0.0108497041461604 0.681492822769963 DataSet_04_011
CD274 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.6 -0.736966 0.255542268271975 0.848572146483105 DataSet_04_013
CD274 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 33.0147 5.04504 0.139987715827919 0.267029183863457 DataSet_04_014
CD274 PAN2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.375 1.24793 0.148319239355266 0.858378518819642 DataSet_04_016
CD274 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.48 -1.05889 0.0094079502566474 0.110564062116725 DataSet_04_019
CD274 SMAD5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.291667 -1.77761 0.441082404330804 0.722648948405705 DataSet_04_020
CD274 XRCC5 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.22222 2.078 0.251495801611572 0.488907971381661 DataSet_04_021
CD274 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.647059 -0.628031 0.320278290257629 0.477124649674405 DataSet_04_023
CD274 E4F1 CRISPR Liver HepG2 4.04545 2.0163 0.00249361324110114 0.161703952963123 DataSet_04_028
CD274 NFX1 CRISPR Liver HepG2 1.65854 0.729911 0.386112597838852 0.480394606136086 DataSet_04_032
CD274 SMAD2 CRISPR Liver HepG2 3.31818 1.73039 0.037824731192347 0.592551633437875 DataSet_04_034
CD274 SMAD4 CRISPR Liver HepG2 0.611111 -0.710493 0.270681645888783 0.431705218394539 DataSet_04_035
CD274 APTX CRISPR Liver HepG2 3.57143 1.8365 0.218269521531028 0.824268978173362 DataSet_04_069
CD274 CHCHD3 CRISPR Liver HepG2 2.33333 1.22239 0.744736006760559 0.910871388241267 DataSet_04_067
CD274 CNOT7 CRISPR Liver HepG2 2 1 0.102045280941458 0.216065931370272 DataSet_04_045
CD274 DNMT3B CRISPR Liver HepG2 0.5 -1 0.255818068553686 0.524241560730318 DataSet_04_044
CD274 PAN2 CRISPR Liver HepG2 0.611111 -0.710493 0.233905381017646 0.40342758520929 DataSet_04_066
CD274 RIOK2 CRISPR Liver HepG2 0.230769 -2.11548 0.551851591709489 1 DataSet_04_070
CD274 ABT1 shRNA Liver HepG2 0.536585 -0.89812 0.522762942945164 0.648535904251864 DataSet_04_052
CD274 CALR shRNA Liver HepG2 4.125 2.04439 0.350235120759612 0.492439061805046 DataSet_04_053
CD274 CCAR1 shRNA Liver HepG2 11.7692 3.55695 0.0090762557401852 0.0457242102780111 DataSet_04_054
CD274 DDX1 shRNA Liver HepG2 11.6 3.53605 0.0106260792488394 0.107307773826147 DataSet_04_057
CD274 PRPF6 shRNA Liver HepG2 1.91111 0.934412 0.372255479549095 0.590681509574496 DataSet_04_056
CD274 UBE2L3 shRNA Liver HepG2 0.210526 -2.24793 0.265079385941812 0.412083665294952 DataSet_04_055
CD274 ACTN4 CRISPR Haematopoietic_and_lymphoid_tissue K562 4.30769 2.10692 0.273332695375023 0.480516833997446 DataSet_04_048
CD274 DDX17 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.28571 1.71621 0.13357087947473 0.659665459957125 DataSet_04_047
CD274 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 17.3333 4.11548 0.0441213249342693 0.390871857665245 DataSet_04_050
CD274 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.88 1.52607 0.112583986688208 0.264474374918432 DataSet_04_046
CD274 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.0810811 -3.62449 0.0648706816350826 1 DataSet_04_077
CD274 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.459459 -1.12199 0.261948659457827 0.647397692393279 DataSet_04_073
CD274 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.7027 1.4344 0.0150413099804837 0.0560241437484667 DataSet_04_049
CD274 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.61765 0.693897 0.369004953635244 0.623641764300489 DataSet_02_38
CD274 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.235294 -2.08746 0.272440067649671 0.429253091932267 DataSet_02_14
CD274 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.323529 -1.62803 0.490826119033177 0.842244084863414 DataSet_02_45
CD274 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.97059 0.978626 0.46024293666068 0.641476866940326 DataSet_02_35
CD274 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.647059 -0.628031 0.637939798109635 0.803154178841447 DataSet_02_32
CD274 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.70588 1.4361 0.20504962156554 0.347826589168594 DataSet_02_47
CD274 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.5 -1 0.680667273104996 0.931952167648722 DataSet_02_49
CD274 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.617647 -0.695145 0.602115296695774 0.765226375130288 DataSet_02_43
CD274 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.558824 -0.839535 0.55266895994522 0.705583579925581 DataSet_02_33
CD274 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.97059 0.978626 0.209076800159961 0.367178791854192 DataSet_02_53
CD274 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 3.3125 1.72792 0.0364252616019217 0.109563794781093 DataSet_04_060
CD274 CCAR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.104478 -3.25873 0.0143760462803421 0.0792518037324458 DataSet_04_064
CD274 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 3.04 1.60407 0.107346223862662 0.263592755631561 DataSet_04_061
CD274 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0298507 -5.06609 0.0209877791079926 0.439304085790495 DataSet_04_063
CD274 HDGF shRNA Haematopoietic_and_lymphoid_tissue K562 0.588235 -0.765535 0.493300076755997 0.625692914990736 DataSet_04_059
CD274 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 0.329412 -1.60204 0.0240939976291391 0.297303882536335 DataSet_04_065
CD274 SMARCA4 siRNA Colon HCT116 1.83555 0.876213 1.137856e-01 9.892536e-01 DataSet_03_301
CD274 ELF3 CRISPR Bile_duct HBDEC2 0.645095 -0.632416 2.766525e-02 6.845844e-02 DataSet_03_304
CD274 HDAC5 siRNA Liver human hepatocytes 1.77764 0.829962 5.174475e-06 2.790277e-04 DataSet_03_346
CD274 SNAI2 shRNA Pancreas KLM1 1.50316 0.588001 9.601155e-02 0.40562576 DataSet_03_307
CD274 INO80 siRNA Muscle RD 2.08696 1.0614 - - DataSet_03_344
CD274 TET1 CRISPR Mammary_gland MDA-MB-231 2.97813 1.57441 4.852833e-06 3.420762e-04 DataSet_03_347
CD274 SKI CRISPR Blood HL60 3.07143 1.61891 2.990036e-02 0.304389351 DataSet_03_351
CD274 ESR1 siRNA Mammary_gland MCF7 0.562588 -0.829848 3.988052e-02 0.1616128463 DataSet_03_352
CD274 ETV5 knockdown Colon HT29 0.0789474 -3.66297 4.807080e-03 0.084578293 DataSet_03_353
CD274 PARP1 siRNA Prostate LNCaP 0.651296 -0.618615 2.656373e-01 0.560894327 DataSet_03_354
CD274 TET1 CRISPR Mammary_gland Hs578T 1.51935 0.603454 3.900598e-02 1.218409e-01 DataSet_03_355
CD274 CREBBP CRISPR Brain U5-NPC 5.14213 2.36237 0.1931836736 0.7490853 DataSet_03_356
CD274 PTPN14 CRISPR Brain U5-NPC 1.852 0.889084 3.923298e-01 0.60809111 DataSet_03_357
CD274 TP53 CRISPR Brain U5-NPC 2.51777 1.33214 6.340785e-02 1.996620e-01 DataSet_03_358
CD274 NCOA3 siRNA Mammary_gland MDA-MB-231 0.601578 -0.733177 9.350206e-03 0.4762984 DataSet_03_361
CD274 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 2.19827 1.13637 5.958177e-04 2.277766e-03 DataSet_03_362
CD274 MYC siRNA Peripheral_blood T lymphocyte 1.81263 0.858082 3.821371e-03 0.043259879 DataSet_03_363
CD274 EP300 shRNA Mammary_gland MCF10AT 0.192385 -2.37793 5.886534e-04 0.019179932 DataSet_03_364
CD274 E2F1 siRNA Nasopharynx HK1 0.388909 -1.36249 1.059125e-01 5.542060e-01 DataSet_03_373
CD274 ZNF213 siRNA Mammary_gland MCF7 0.117219 -3.09273 4.905668e-01 7.201832e-01 DataSet_03_376
CD274 EZH2 CRISPR Ovary SKOV3 0.427586 -1.22571 8.096510e-03 0.0676606520 DataSet_03_378
CD274 DDX5 shRNA Stomach HGC-27 0.439024 -1.18763 - - DataSet_03_379
CD274 NFKB2 siRNA Bone_marrow U2OS 3.23628 1.69433 1.418902e-03 0.06994625 DataSet_03_381
CD274 YY1 shRNA Brain GSC1517 0.5 -1 - - DataSet_03_384
CD274 YY1 shRNA Brain GSC23 0.461538 -1.11548 - - DataSet_03_385
CD274 YY1 shRNA Brain GSC3028 0.333333 -1.58496 - - DataSet_03_386
CD274 TRIM8 siRNA Mammary_gland MCF7 1.93103 0.949374 3.661328e-01 0.5702193705 DataSet_03_388
CD274 NFKBIA shRNA Bone_marrow U2OS 0.500314 -0.999094 6.363272e-01 0.87005461 DataSet_03_389
CD274 YY1 knockdown Liver HepG2 7 2.80735 1.566946e-01 3.190475e-01 DataSet_03_390
CD274 ILF2 siRNA Stomach SGC-7901 2.0122 1.00877 0.2881894974 0.48980285 DataSet_03_393
CD274 ASXL1 CRISPR Embryo iPSC 0.400162 -1.32134 0.2881467774 0.8230067 DataSet_03_394
CD274 JAZF1 siRNA Cervix HeLa Kyoto 2.44513 1.28991 4.139029e-02 0.600281126 DataSet_03_396
CD274 HMGA1 shRNA Bile_duct HUCCT1 4 2 1.081574e-02 0.125817934 DataSet_03_400
CD274 EHF shRNA Stomach MKN7 0.181989 -2.45807 - - DataSet_03_402
CD274 JARID2 siRNA Adipose_tissue human adipose tissue derived stem cells 1.60181 0.679703 9.576104e-02 0.3277549 DataSet_03_403
CD274 CDK7 shRNA Bone_marrow D458 10.3333 3.36923 1.726844e-01 0.51117207 DataSet_03_404
CD274 TFAP2A knockout Embryo H9 1.55 0.632268 1.165479e-01 0.24504951 DataSet_03_405
CD274 CHD1 shRNA Prostate LNCaP 0.341966 -1.54807 1.144126e-04 1.622046e-02 DataSet_03_407
CD274 MAP3K7 shRNA Prostate LNCaP 1.5444 0.627044 1.418394e-02 9.931171e-02 DataSet_03_408
CD274 STRAP knockout Nerve SK-N-AS 1.76597 0.820462 - - DataSet_03_409
CD274 SIRT1 siRNA Pancreas PANC1 3.6 1.848 1.270943e-02 0.057519363 DataSet_03_410
CD274 RUNX2 shRNA Cord_blood Natural Killer Cell 0.428571 -1.22239 1.754865e-01 0.793390621 DataSet_03_416
CD274 FOXK2 shRNA Ovary OVCAR-5 0.375 -1.41504 3.458185e-02 0.15120289 DataSet_03_419
CD274 MAEL CRISPR Liver Alexander cells 0.172414 -2.53605 - - DataSet_03_423
CD274 FOXP3 CRISPR Peripheral_blood Naive Treg 0.606614 -0.721148 2.250804e-01 0.577770447 DataSet_03_427
CD274 LHX2 shRNA Bone_marrow ES-derived RPE cells 2.11852 1.08306 9.674589e-02 1.000000e+00 DataSet_03_428
CD274 USP7 shRNA Skin xenograft cells 0.577061 -0.793204 0.30301081 0.4462854 DataSet_03_431
CD274 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.294776 -1.76231 - - DataSet_03_432
CD274 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 1.93494 0.95229 1.587378e-02 0.366588920 DataSet_03_434
CD274 POU2AF1 CRISPR Lymph SUDHL4 3 1.58496 1.364940e-01 0.271751988 DataSet_03_435
CD274 SUFU shRNA Mammary_gland HCC1954 cells 0.121369 -3.04253 0.5104224483 0.7880076 DataSet_03_437
CD274 CIC knockout Brain Immortalized Astrocyte Cells 0.343553 -1.54139 1.686181e-02 2.423608e-01 DataSet_03_438
CD274 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.590164 -0.760812 7.748326e-01 0.99868088 DataSet_03_439
CD274 FOSL1 siRNA Prostate MSKPCa3 0.482904 -1.05019 0.0047771153 0.2326828 DataSet_03_445
CD274 CBX2 siRNA Mammary_gland MCF7 4.03797 2.01363 1.701821e-02 0.0462374113 DataSet_03_451
CD274 SMARCA2 shRNA Lung HCC2302 1.60838 0.685606 3.328559e-03 4.797933e-03 DataSet_03_455
CD274 TXNIP shRNA Cord_Blood CD34+ cells 3.6875 1.88264 - - DataSet_03_461
CD274 SOX9 knockout Liver HuH7 0.428571 -1.22239 1.300500e-01 2.677489e-01 DataSet_03_463
CD274 PARP1 knockout Embryo_kidney HEK293a 1.66947 0.739388 8.586463e-03 2.796831e-02 DataSet_03_464
CD274 STAT3 shRNA Liver HepG2 2 1 2.305925e-01 0.5909364897 DataSet_03_465
CD274 SMARCA1 Cas13 Embryo_kidney HEK293T 2 1 - - DataSet_03_466
CD274 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 5.33333 2.41504 - - DataSet_03_467
CD274 SMARCA1 shRNA Embryo_kidney HEK293T 2.66667 1.41504 - - DataSet_03_468
CD274 CREBBP CRISPR Lymph U2932 1.61905 0.695145 1.497782e-01 1.0000000 DataSet_03_474
CD274 CHCHD3 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.42857 1.28011 0.5021067 0.9486302 DataSet_04_071
CD274 APTX CRISPR Haematopoietic_and_lymphoid_tissue K562 4.16667 2.05889 0.06774962 0.4878886 DataSet_04_072
CD274 CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 5.57143 2.47805 0.06084158 0.143501424 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate NONO by the evidences of both expression and ChIP-seq/motif
Expression Atlas of CD274
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines