Gene Overview
| Target Gene: | Myl4 |
| NCBI Official Symbol: | Myl4 |
| Entrez ID: | 17896 |
| Ensembl ID: | ENSMUSG00000061086 |
| Gene Full Name: | myosin, light polypeptide 4 |
| Strand: | + |
| Gene Locus: | 11 E1|11 67.79 cM |
| External Links: |
|
Myl4 Significantly Regulated by These T(co)Fs
T(co)Fs
that Activate Myl4
T(co)Fs
that Repress Myl4
The Intensity of the Gene Regulated by T(co)Fs:
Myl4-T(co)F Pairs
| Target Gene |
T(co)F | Knock -Method |
Tissue Type | Biosample Name |
Fold Change |
Log2FC | P-value | Corrected _P |
Dataset ID |
|---|---|---|---|---|---|---|---|---|---|
| Myl4 | Bcl11a | knockout | Bone_marrow | Bone marrow erythoid progenitors | 0.660623 | -0.5981 | 0.0361265692423723 | 0.349796940283287 | DataSet_11_013 |
| Myl4 | Bcl6 | knockout | Bone_marrow | Bone marrow-derived macrophages | 2.19527 | 1.1344 | 0.510439244927745 | 0.780063393681577 | DataSet_11_014 |
| Myl4 | Bhlha9 | knockout | Limb | Whole limb bud | 9.98983 | 3.32046 | - | - | DataSet_11_016 |
| Myl4 | Cebpa | shRNA | Bone_marrow | Marrow progenitors | 0.563923 | -0.82643 | 0.000393437688092849 | 0.0225956813399335 | DataSet_11_019 |
| Myl4 | Dmrt1 | knockout | Testis | Testes | 1.56672 | 0.647744 | 0.0211582993998792 | 0.766596077573069 | DataSet_11_024 |
| Myl4 | Dmrt1 | knockout | Testis | Juvenile testes | 0.621172 | -0.686934 | 0.021856523901374 | 0.564130128272585 | DataSet_11_027 |
| Myl4 | E2f4 | knockout | Brain | Forebrain | 0.488775 | -1.03276 | - | - | DataSet_11_033 |
| Myl4 | Elf5 | knockout | Mammary_gland | Mammary gland | 1.53954 | 0.622501 | 0.250513506696289 | 0.531930860195304 | DataSet_11_035 |
| Myl4 | Esrrb | shRNA | Embryo | ES cells | 0.591502 | -0.757544 | - | - | DataSet_11_039 |
| Myl4 | Gfi1b | knockout | Bone_marrow | Ter119 positive erythroid cells | 0.445291 | -1.16718 | - | - | DataSet_11_054 |
| Myl4 | Hsf4 | knockout | Eye | Lens | 0.169411 | -2.5614 | 0.0714124673664346 | 0.987999303842427 | DataSet_11_058 |
| Myl4 | Jarid2 | knockout | Pancreas | Embryonic pancreas | 0.120419 | -3.05387 | 0.20138427151026 | 0.814778590325536 | DataSet_11_064 |
| Myl4 | Klf17 | shRNA | Mammary_gland | 168FARN | 0.536427 | -0.898545 | 0.00181621061991986 | 0.0161953653419965 | DataSet_11_066 |
| Myl4 | Lhx8 | knockout | Ovary | Ovary | 2.58358 | 1.36937 | 0.00234497103820357 | 0.0252050802123051 | DataSet_11_070 |
| Myl4 | Lmx1b | knockout | Kidney | Kidney | 1.70524 | 0.769972 | 0.061340218237117 | 0.438683654746566 | DataSet_11_072 |
| Myl4 | Mef2a | shRNA | Muscle | C2C12 | 0.601332 | -0.733767 | 4.89773288235605e-07 | 3.3046898002378e-05 | DataSet_11_077 |
| Myl4 | Myb | shRNA | Lung | Tracheal epithelial cell | 0.180961 | -2.46625 | 0.000314383234513955 | 0.0190288158161005 | DataSet_11_085 |
| Myl4 | Nhlh2 | knockout | Eye | Retina | 0.472705 | -1.08099 | 0.175006266235083 | 0.523726874680013 | DataSet_11_092 |
| Myl4 | Nr2f2 | knockout | Ovary | E14.5 Ovary | 3.27181 | 1.71009 | 0.00137689951013958 | 0.475060234221242 | DataSet_11_094 |
| Myl4 | Nrf1 | knockdown | Liver | Liver | 1.50231 | 0.587178 | 0.0277082538760235 | 0.0800487816267109 | DataSet_11_096 |
| Myl4 | Otx2 | knockout | Eye | Retina | 0.6125 | -0.707218 | 0.835862211887764 | 0.999923528647439 | DataSet_11_097 |
| Myl4 | Pitx2 | knockout | Eye | Cornea | 2.97237 | 1.57161 | 0.426810330171457 | 0.724129030570014 | DataSet_11_103 |
| Myl4 | Pparg | siRNA | Adipose_tissue | Preadipocytes | 0.643888 | -0.635119 | 0.00967595216540127 | 0.203131446853519 | DataSet_11_105 |
| Myl4 | Prdm2 | shRNA | Muscle | C2C12 | 1.93054 | 0.949001 | 0.0377643243610187 | 0.761041192303511 | DataSet_11_108 |
| Myl4 | Prox1 | knockout | Liver | Liver | 2.00795 | 1.00572 | - | - | DataSet_11_109 |
| Myl4 | Rest | knockout | Brain | Brain | 1.6886 | 0.755829 | 0.214114044593528 | 1 | DataSet_11_113 |
| Myl4 | Runx1 | knockout | Bone_marrow | KSL cells | 0.456101 | -1.13258 | 0.0299560233315966 | 0.676645401357633 | DataSet_11_115 |
| Myl4 | Runx1 | knockout | Lymph | ProB cells | 0.0873431 | -3.51716 | 2.2404351647091e-05 | 0.00379977803934664 | DataSet_11_116 |
| Myl4 | Sall1 | knockout | Kidney | Kidney | 1.97169 | 0.979434 | 0.0884321620166201 | 0.469069027258496 | DataSet_11_121 |
| Myl4 | Sall1 | knockout | Kidney | Kidney | 0.238538 | -2.06771 | 0.502128732045231 | 0.999095636270846 | DataSet_11_122 |
| Myl4 | Sall4 | shRNA | Embryo | ES cells | 0.5 | -1 | 0.0681007656594905 | 0.934656681675898 | DataSet_11_123 |
| Myl4 | Smad4 | siRNA | Brain | bEnd3 | 0.185108 | -2.43356 | - | - | DataSet_11_127 |
| Myl4 | Snai1 | knockout | Embryo | Embryoid body | 0.53915 | -0.891242 | - | - | DataSet_11_129 |
| Myl4 | Snai1 | knockout | Embryo | Embryonic stem cells (ESCs) | 0.432279 | -1.20997 | 0.0028593250805578 | 0.999994003527217 | DataSet_11_132 |
| Myl4 | Sohlh1 | knockout | Ovary | Ovary | 0.195874 | -2.352 | 4.38277915964926e-06 | 0.000160399027537895 | DataSet_11_134 |
| Myl4 | Sohlh2 | knockout | Ovary | Ovary | 0.232586 | -2.10417 | 2.28905227851154e-08 | 2.82859536557011e-06 | DataSet_11_135 |
| Myl4 | Sox2 | shRNA | Embryo | ES cells | 0.471425 | -1.0849 | - | - | DataSet_11_140 |
| Myl4 | Sox2 | siRNA | Embryo | NG4 | 2.30308 | 1.20356 | 0.00239884530513445 | 0.052353360837781 | DataSet_11_141 |
| Myl4 | Sox6 | knockout | Heart | Cardiac ventricle | 2.08842 | 1.06241 | 0.275921569328129 | 0.999873206585343 | DataSet_11_143 |
| Myl4 | Sox9 | knockout | Lung | Trachea | 1.65439 | 0.726299 | 0.00240456124159735 | 0.0674338270998696 | DataSet_11_144 |
| Myl4 | Sp3 | knockout | Heart | Heart | 1.5054 | 0.590142 | 0.272717869955963 | 0.806479025809203 | DataSet_11_145 |
| Myl4 | Srf | knockout | Aorta | Aorta | 0.646176 | -0.63 | 0.26964052012098 | 0.993526315825099 | DataSet_11_148 |
| Myl4 | Stat4 | knockout | Lymph | Lamina propria lymphocytes | 0.59836 | -0.740915 | 0.294643321714808 | 0.924261066168849 | DataSet_11_152 |
| Myl4 | Tet2 | shRNA | Macrophage_cells | HAFTL | 1.70144 | 0.766759 | 4.03885034771143e-05 | 0.150344575699612 | DataSet_11_160 |
| Myl4 | Thap1 | knockout | Brain | Cerebellum | 0.103173 | -3.27687 | 7.76634900221944e-09 | 1.60912225954222e-06 | DataSet_11_164 |
| Myl4 | Thap1 | knockout | Brain | Cortex | 0.115753 | -3.11087 | 7.59307970196131e-09 | 1.40394494081162e-06 | DataSet_11_165 |
| Myl4 | Yy1 | knockout | Muscle | Skeletal muscle | 6.3185 | 2.65958 | 3.52916713893237e-07 | 4.95447024478555e-05 | DataSet_11_182 |
| Myl4 | Hipk2 | knockout | Heart | cardiac tissue | 0.370593 | -1.4321 | 6.011922e-02 | 3.149010e-01 | DataSet_11_238 |
| Myl4 | Kdm5b | knockout | Heart | left ventricles | 7.40564 | 2.88862 | 0.3147141252 | 0.9999827 | DataSet_11_210 |
| Myl4 | Ncoa3 | shRNA | Embryo | ES cells | 0.207491 | -2.26888 | 2.765001e-15 | 2.845094e-12 | DataSet_11_194 |
| Myl4 | Ncoa3 | shRNA | Embryo | ES cells | 0.207491 | -2.26888 | 2.765001e-15 | 2.845094e-12 | DataSet_11_195 |
| Myl4 | Dnmt3l | shRNA | Embryo | ES cells | 1.73858 | 0.797909 | 1.338307e-03 | 1.464346e-02 | DataSet_11_231 |
| Myl4 | Bptf | knockout | Embryo | Embryonic fibroblasts | 1.55881 | 0.640445 | 3.837366e-03 | 0.22099936 | DataSet_11_197 |
| Myl4 | Ezh2 | knockout | Bone_marrow | CD45.2+LSK cells | 26.2905 | 4.71647 | - | - | DataSet_11_220 |
| Myl4 | Ezh2 | knockdown | Brain | Brain | 11.4333 | 3.51517 | 4.195327e-06 | 0.0021531608 | DataSet_11_221 |
| Myl4 | Cebpa | shRNA | Bone_marrow | lineage-negative marrow progenitors | 0.563923 | -0.82643 | 2.531949e-04 | 0.019258116 | DataSet_11_199 |
| Myl4 | Dnmt3b | knockout | Heart | Cardiac ventricle | 3.35445 | 1.74608 | 3.479750e-02 | 9.999725e-01 | DataSet_11_205 |
| Myl4 | Dnmt3a | siRNA | Peritoneum | peritoneal macrophages | 1.87981 | 0.910588 | - | - | DataSet_11_222 |
| Myl4 | Smarca4 | shRNA | Embryo | ES cells | 0.300879 | -1.73275 | - | - | DataSet_11_224 |
| Myl4 | Smarca4 | shRNA | Embryo | ES cells | 0.300879 | -1.73275 | - | - | DataSet_11_225 |
| Myl4 | Rag1 | knockout | Bone | Mice fractured callus | 2.16091 | 1.11164 | 1.166508e-03 | 8.821836e-03 | DataSet_11_230 |
| Myl4 | Dnmt3a | siRNA | Embryo | iPSC | 2.02639 | 1.01891 | - | - | DataSet_11_241 |
| Myl4 | Kat6a | knockout | Embryo | Embryonic fibroblasts | 0.610723 | -0.711411 | 6.448267e-02 | 0.3402558091 | DataSet_11_245 |
| Myl4 | Fubp1 | shRNA | Brain | brain neural progenitors | 1.85982 | 0.895159 | 0.1965039636 | 1 | DataSet_11_246 |
| Myl4 | Tet1 | shRNA | Muscle | MLL-ENL-ERtm | 0.474232 | -1.07633 | 1.710410e-02 | 3.863155e-02 | DataSet_11_249 |
| Myl4 | Kmt2d | knockout | Skin | iBiP melanoma mouse model tumor cell | 0.467249 | -1.09774 | 1.691745e-01 | 3.366175e-01 | DataSet_11_250 |
| Myl4 | Kdm2a | CRISPR | Embryo | ES cells | 0.340659 | -1.5536 | 0.0816117509 | 1.0000000 | DataSet_11_251 |
| Myl4 | Zbp1 | siRNA | Bone_marrow | bone marrow-derived mesenchymal stem_progenitor cells | 0.22031 | -2.18239 | 4.579995e-02 | 0.143529488 | DataSet_11_252 |
| Myl4 | Crebbp | shRNA | Lung | preSC | 0.58 | -0.785875 | 2.196348e-01 | 0.63287658 | DataSet_11_255 |
| Myl4 | Eed | knockout | Spinal_cord | spinal cord | 0.329973 | -1.59958 | 3.636539e-01 | 9.999790e-01 | DataSet_11_261 |
| Myl4 | Mef2d | CRISPR | Heart | Cardiac ventricle | 0.637331 | -0.649885 | 5.531626e-01 | 0.7530748486 | DataSet_11_270 |
| Myl4 | Myc | CRISPR | Skeletal_muscle | muscle stem cells | 0.0402568 | -4.63462 | 1.609738e-02 | 0.35193264 | DataSet_11_272 |
| Myl4 | Myod1 | CRISPR | Skeletal_muscle | myoblast | 0.000868087 | -10.1699 | 4.076077e-11 | 9.009475e-08 | DataSet_11_275 |
| Myl4 | Ezh2 | siRNA | Bone_marrow | Mesenchymal stem cells | 1.53469 | 0.617951 | 2.384559e-02 | 1.712584e-01 | DataSet_11_276 |
| Myl4 | Dnmt1 | knockout | Cortex | mature Pvergic cortical interneurons | 2 | 1 | 2.790451e-02 | 0.6936949 | DataSet_11_283 |
| Myl4 | Zmat3 | knockout | Embryo | Embryonic fibroblasts | 0.336437 | -1.57159 | 2.256631e-01 | 0.5395938 | DataSet_11_284 |
| Myl4 | Usp7 | siRNA | Embryo | ES cells | 0.662281 | -0.594485 | 5.069727e-01 | 0.7555373 | DataSet_11_287 |
| Myl4 | Mkl1 | knockout | Bone_marrow | Bone marrow differentiated macrophages | 3 | 1.58496 | 1.272971e-03 | 0.2225195152 | DataSet_11_294 |
| Myl4 | Sirt3 | knockout | Pancreatic_islets | pancreatic beta cell | 1.54808 | 0.630477 | 5.330112e-02 | 4.861371e-01 | DataSet_11_297 |
| Myl4 | Phf8 | knockout | prostate | Prostate | 1.69444 | 0.760812 | 0.0522796035 | 0.2668373 | DataSet_11_298 |
| Myl4 | Hmg20a | siRNA | Hypothalamus | Primary hypothalamic astrocytes | 1.76471 | 0.819428 | 0.0021275802 | 0.2101973 | DataSet_11_300 |
| Myl4 | Satb2 | CRISPR | Colon | Colon organoid | 2.44444 | 1.28951 | 1.185953e-01 | 0.6518149 | DataSet_11_304 |
| Myl4 | Foxp3 | CRISPR | Spleens_and_lymphnodes | CD4+ Th0 cells | 0.62844 | -0.670152 | - | - | DataSet_11_305 |
| Myl4 | Cited2 | knockout | Haematopoietic_and_lymphoid_tissue | Hematopoietic stem cell (HSC) | 0.594203 | -0.750973 | - | - | DataSet_11_308 |
| Myl4 | Suz12 | knockout | Lung | Alveolar macrophage | 4.06061 | 2.02169 | 9.688515e-02 | 0.4960114987 | DataSet_11_311 |
| Myl4 | Actl6a | knockout | Nerve | sciatic nerve | 4.57164 | 2.19271 | 1.040525e-01 | 0.383610804 | DataSet_11_314 |
| Myl4 | Satb2 | knockout | Colon | Intestine epithelium | 0.6 | -0.736966 | 1.216859e-01 | 0.4740826035 | DataSet_11_316 |
| Myl4 | Arid1b | knockout | Bone_marrow | bone marrow leukemia cells | 6 | 2.58496 | 1.406634e-02 | 0.1500354997 | DataSet_11_317 |
| Myl4 | Arid2 | knockout | Bone_marrow | bone marrow leukemia cells | 0.5625 | -0.830075 | 1.731200e-01 | 0.7527440 | DataSet_11_318 |
| Myl4 | Kat7 | knockout | Thymic_lobes | Thymic epithelial cells | 0.58952 | -0.762388 | 2.763421e-01 | 5.586256e-01 | DataSet_11_319 |
| Myl4 | Gata2 | knockout | Brain | Pituitary gland | 1.7 | 0.765535 | 0.888449674 | 1.0000000 | DataSet_11_322 |
| Myl4 | Kdm5b | siRNA | Embryo | ES cells | 0.306734 | -1.70494 | 0.1574328991 | 0.8933528 | DataSet_11_331 |
| Myl4 | Ezh2 | shRNA | Brain | SVZ derived neural stem cells | 2.74074 | 1.45457 | 1.299781e-02 | 1.133666e-01 | DataSet_11_332 |
| Myl4 | Ezh2 | knockout | Eye | Retina | 0.625 | -0.678072 | 2.683762e-01 | 8.864089e-01 | DataSet_11_333 |
| Myl4 | Ezh2 | knockout | Eye | Retina | 0.617322 | -0.695904 | 0.6933217872 | 1.0000000 | DataSet_11_334 |
| Myl4 | Atrx | knockout | Embryo | ES cells | 0.32 | -1.64386 | - | - | DataSet_11_335 |
| Myl4 | Dnmt3a | siRNA | Heart | embryonic cardiomyocytes | 2.02913 | 1.02086 | 1.258048e-02 | 0.34240443 | DataSet_11_337 |
| Myl4 | Dnmt3b | siRNA | Heart | embryonic cardiomyocytes | 3.44525 | 1.78461 | 4.443719e-04 | 0.11324631 | DataSet_11_338 |
| Myl4 | Gtf2ird1 | knockout | Lip | Lip | 0.636656 | -0.651414 | 7.378781e-02 | 4.348582e-01 | DataSet_11_339 |
| Myl4 | Ezh2 | knockout | Small_intestinal_crypts | small intestinal crypts | 0.0863309 | -3.53398 | 0.0102976362 | 0.1712697 | DataSet_11_341 |
| Myl4 | Dux | shRNA | Embryo | ES cells | 2.31304 | 1.20979 | 9.361369e-02 | 5.733358e-01 | DataSet_11_345 |
Regulation Region
Expression Atlas of Myl4