Gene Overview
Target Gene: NR2F1
NCBI Official Symbol: NR2F1
Entrez ID: 7025
Ensembl ID: ENSG00000175745
Gene Full Name: nuclear receptor subfamily 2 group F member 1
Strand: +
Gene Locus: 5q15
External Links:

NR2F1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate NR2F1   
T(co)Fs that Repress NR2F1
The Intensity of the Gene Regulated by T(co)Fs:
NR2F1-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
NR2F1 HNF1B shRNA Ovary RMG2 7.05651 2.81895 9.87058e-05 0.00062 DataSet_01_103
NR2F1 FOXO1 shRNA Bone EWS-FLI1 0.44536 -1.16696 0.02906 0.32614 DataSet_01_106
NR2F1 SPDEF shRNA Mammary_gland MCF7 2.95303 1.5622 0.46107 0.99999 DataSet_01_107
NR2F1 GABPA siRNA Lung A549 1.56855 0.64943 4.20978e-08 1.06011e-06 DataSet_01_113
NR2F1 TCF3 shRNA Mammary_gland MDA-MB468 1.85739 0.89327 4.3213e-07 5.1968e-05 DataSet_01_116
NR2F1 ID1 siRNA Lung A549 1.62669 0.70194 0.03023 0.19832 DataSet_01_117
NR2F1 ID1 siRNA Lung H1650 1.81773 0.86214 0.05122 0.3725 DataSet_01_118
NR2F1 ID1 shRNA Neuroepithelium GSC8 0.55391 -0.85228 1.20222e-10 7.5232e-10 DataSet_01_134
NR2F1 SPDEF shRNA Mammary_gland MCF7 1.93293 0.95079 2e-04 0.02107 DataSet_01_135
NR2F1 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.1875 1.12928 0.0398 0.60825 DataSet_01_137
NR2F1 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.36328 1.24079 0.03286 0.99993 DataSet_01_138
NR2F1 GATA3 siRNA Peripheral_blood CD4+ T cells 3.63202 1.86077 0.00047 0.04301 DataSet_01_163
NR2F1 MAF siRNA Peripheral_blood CD4+ T cells 2.77847 1.47429 0.00148 0.03174 DataSet_01_165
NR2F1 NFATC3 siRNA Peripheral_blood CD4+ T cells 2.61622 1.38748 0.00249 0.04065 DataSet_01_166
NR2F1 NFKB1 siRNA Peripheral_blood CD4+ T cells 3.93638 1.97687 7.1064e-05 0.02199 DataSet_01_167
NR2F1 STAT3 siRNA Peripheral_blood CD4+ T cells 1.65063 0.72301 0.13134 0.99183 DataSet_01_168
NR2F1 HSF1 shRNA Liver KYN2 1.53945 0.62242 - - DataSet_01_178
NR2F1 GATA2 siRNA Prostate LNCaP 0.16475 -2.60168 2.32861e-05 0.00037 DataSet_01_193
NR2F1 CREB1 shRNA Parotid_gland H3118 MEC 0.6445 -0.63376 0.15754 0.51188 DataSet_01_194
NR2F1 TP63 siRNA Head_and_neck SCC-1 2.82164 1.49654 - - DataSet_01_198
NR2F1 TP63 siRNA Immortalized_keratinocyte HaCaT 1.61222 0.68905 - - DataSet_01_200
NR2F1 XBP1 shRNA Mammary_gland T47D 3.25069 1.70075 1.95022e-06 0.00021 DataSet_01_203
NR2F1 HIC1 shRNA Mammary_gland HBL100 0.29624 -1.75518 - - DataSet_01_205
NR2F1 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly7 0.44569 -1.16588 - - DataSet_01_210
NR2F1 EGR3 shRNA Prostate M12 2.36025 1.23894 0.03203 0.18868 DataSet_01_212
NR2F1 LIN28A siRNA Embryo H9 0.41869 -1.25603 0.00061 0.00908 DataSet_01_215
NR2F1 ERG siRNA Prostate VCaP 0.63689 -0.65088 0.00936 0.08748 DataSet_01_216
NR2F1 TAL1 shRNA Haematopoietic_and_lymphoid_tissue HEL 1.58949 0.66857 0.0311 0.10984 DataSet_01_217
NR2F1 KLF9 siRNA Liver HepG2 0.62343 -0.68171 4.36477e-11 9.59107e-09 DataSet_01_222
NR2F1 SNAI2 shRNA Skin Primary human keratinocytes 4.23308 2.08171 0.00047 0.01167 DataSet_01_225
NR2F1 KLF2 shRNA Bone_marrow RPMI8226 2.33411 1.22287 0.10396 0.71174 DataSet_01_226
NR2F1 ARNT shRNA Embryo hESC HSF1 0.22215 -2.17043 0.37177 0.99999 DataSet_01_240
NR2F1 TWIST1 shRNA Stomach CAF32 0.64938 -0.62287 0.01076 0.05448 DataSet_01_253
NR2F1 YBX1 shRNA Mammary_gland MDA 2.943 1.55729 0.04644 0.15521 DataSet_01_257
NR2F1 YBX1 shRNA Mammary_gland MDA 0.65253 -0.61589 4.77703e-05 0.00044 DataSet_01_259
NR2F1 SOX4 shRNA Mammary_gland MDA-MB-231 0.22313 -2.16403 1.12835e-05 0.00293 DataSet_01_260
NR2F1 MSX1 siRNA Tooth Dental Pulp Cells 1.79101 0.84077 1.16002e-05 0.00027 DataSet_01_281
NR2F1 ZIC5 siRNA Skin A375 1.80766 0.85412 - - DataSet_01_284
NR2F1 POSTN shRNA Brain GSC272 1.82793 0.87021 0.15242 0.57242 DataSet_01_293
NR2F1 TFAP4 siRNA Brain BE(2)-C 0.17344 -2.52747 0.27884 0.51625 DataSet_01_295
NR2F1 PTEN shRNA Skin A431 13.6712 3.77307 0.00468 0.07768 DataSet_01_301
NR2F1 PTEN shRNA Lung HCC827 3.50339 1.80875 0.34728 0.75157 DataSet_01_302
NR2F1 PTEN shRNA Mammary_gland SKBR3 0.20382 -2.29464 0.04087 0.55832 DataSet_01_303
NR2F1 SOX9 siRNA Prostate VCaP 1.91021 0.93373 0.05697 0.9316 DataSet_01_308
NR2F1 SOX9 siRNA Prostate VCaP 1.91021 0.93373 0.05697 0.9316 DataSet_01_309
NR2F1 ELK3 shRNA Mammary_gland MDA-MB-231 2.52561 1.33663 0.00061 0.00232 DataSet_01_318
NR2F1 MYC siRNA Colon HCT116 1.50738 0.59205 0.03558 0.06034 DataSet_01_324
NR2F1 TCF7L1 shRNA Colon HCT116 2.77617 1.4731 2.73014e-05 0.00299 DataSet_01_346
NR2F1 SOX2 shRNA Neuroepithelium HF2303 0.59876 -0.73996 0.12459 1 DataSet_01_349
NR2F1 ETV4 shRNA Prostate PC3 2.10378 1.07298 - - DataSet_01_356
NR2F1 CDX2 siRNA Colon COLO320 1.67494 0.74411 - - DataSet_01_357
NR2F1 PAX3 shRNA Soft_tissue Rh30 1.86771 0.90127 - - DataSet_01_359
NR2F1 SOX17 siRNA Umbilical_vein HUVEC 1.86352 0.89803 - - DataSet_01_360
NR2F1 GTF2B siRNA Cervix HeLa 2.02302 1.01651 - - DataSet_01_362
NR2F1 SAFB2 shRNA Liver HepG2 3.44747 1.78554 0.00017 0.02192 DataSet_02_102
NR2F1 TAF15 shRNA Liver HepG2 0.36774 -1.44323 0.00032 0.01075 DataSet_02_106
NR2F1 SSB shRNA Liver HepG2 0.47161 -1.08432 0.00958 0.02605 DataSet_02_107
NR2F1 HNRNPUL1 shRNA Liver HepG2 1.68816 0.75545 0.00254 0.02452 DataSet_02_109
NR2F1 PCBP1 shRNA Liver HepG2 1.98262 0.98741 0.00556 0.02431 DataSet_02_115
NR2F1 TARDBP shRNA Liver HepG2 2.11232 1.07883 0.00848 0.03421 DataSet_02_116
NR2F1 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 6 2.58496 0.13028 0.40491 DataSet_02_138
NR2F1 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.02621 0.06475 DataSet_02_143
NR2F1 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 1.66667 0.73697 0.09481 0.52093 DataSet_02_146
NR2F1 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.26316 -1.926 0.07897 0.51162 DataSet_02_150
NR2F1 ZFX siRNA Mammary_gland MCF7 0.32353 -1.62803 0.01481 0.10881 DataSet_02_206
NR2F1 AR siRNA Prostate LNCaP 0.282609 -1.82312 0.103489798717448 1 DataSet_03_005
NR2F1 ARID2 CRISPR Liver JHH4 1.63338 0.707856 0.530508825129362 1 DataSet_03_015
NR2F1 BCL6 siRNA Lymph OCI-Ly7 DLBCL 1.5213 0.605301 0.70150432779775 0.953758687523968 DataSet_03_025
NR2F1 BCL6 siRNA Lymph Pfeiffer DLBCL 0.486618 -1.03914 0.240554532349156 0.707292382623351 DataSet_03_026
NR2F1 FOXF2 siRNA Mammary_gland MCF10A 0.660286 -0.598837 - - DataSet_03_086
NR2F1 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 2.29383 1.19776 - - DataSet_03_096
NR2F1 GATA2 siRNA Uterus Decidual stromal cells 0.520556 -0.941876 0.421799418434967 0.910656573333431 DataSet_03_100
NR2F1 GATA6 siRNA Stomach YCC3 1.63963 0.713372 0.0541257772745925 0.636463621667502 DataSet_03_110
NR2F1 HMGA2 siRNA Mammary_gland MDA-MB-231 1.59539 0.673906 0.0216684737612472 0.668831985856449 DataSet_03_125
NR2F1 KLF5 siRNA Stomach YCC3 2.09308 1.06563 0.0205391579302077 0.228801756401454 DataSet_03_151
NR2F1 MEF2D shRNA Liver HuH7 2.92725 1.54955 - - DataSet_03_162
NR2F1 MITF siRNA Skin Ma-Mel-15 2.22271 1.15232 0.00456237343757729 0.137728881684774 DataSet_03_166
NR2F1 MITF siRNA Skin Ma-Mel-15 2.25976 1.17617 0.000241966108010051 0.0114343820469164 DataSet_03_167
NR2F1 MYB siRNA Cord_Blood CD34+ progenitor cells 12.6791 3.66438 - - DataSet_03_170
NR2F1 MYC siRNA Central_nervous_system DAOY M2.1 1.70313 0.768188 1.78366323649669e-06 1.25041202286617e-05 DataSet_03_178
NR2F1 MYCN CRISPR Neuroblastoma CHP-134 0.621104 -0.687093 0.000440766073500548 0.00600629348536721 DataSet_03_183
NR2F1 MYCN CRISPR Neuroblastoma CHP-134 0.621104 -0.687093 0.000440766073500548 0.00600629348536721 DataSet_03_184
NR2F1 SOX4 siRNA Haematopoietic_and_lymphoid_tissue ST1 1.66767 0.737829 - - DataSet_03_246
NR2F1 SP1 siRNA Cervix HeLa 0.555892 -0.847122 6.63128172565853e-05 0.00141617757168773 DataSet_03_249
NR2F1 SP1 siRNA Ovary OVSAYO 10.0806 3.33351 0.027178867417209 0.206365033687989 DataSet_03_251
NR2F1 STAT3 CRISPR Embryo hESC 10.1658 3.34566 0.00190450326400895 0.0317300130193813 DataSet_03_258
NR2F1 STAT3 siRNA Prostate DU145 1.76721 0.821472 6.13627656030903e-05 0.00727109459844482 DataSet_03_260
NR2F1 STAT6 siRNA Umbilical_vein HUVEC 0.611359 -0.709908 0.0863332568332083 0.798957643496596 DataSet_03_264
NR2F1 TFE3 siRNA Kidney UOK257-2 0.655423 -0.609503 - - DataSet_03_275
NR2F1 ZNF165 siRNA Mammary_gland WHIM12 0.541411 -0.885204 0.594437287244445 0.999997668745677 DataSet_03_289
NR2F1 NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 280.154 8.13008 0.0409451168969152 0.120009586670891 DataSet_04_014
NR2F1 ACTN4 CRISPR Liver HepG2 0.418104 -1.25806 0.0017453194553611 0.0326534106992529 DataSet_04_042
NR2F1 DDX20 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.57143 0.652077 0.671685908196953 0.903085639999323 DataSet_04_050
NR2F1 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.0591590270813758 0.240106259665312 DataSet_02_38
NR2F1 DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.296743750512875 0.455512909152704 DataSet_02_14
NR2F1 NFE2L1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.16667 1.66297 0.218565044704992 0.497880634996649 DataSet_02_32
NR2F1 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.53333 1.34104 0.128066709286772 0.243207606402107 DataSet_02_47
NR2F1 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.534884 -0.902703 0.507571195243972 0.841741493086311 DataSet_02_49
NR2F1 TLE2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 2.6 1.37851 0.159383812564708 0.304685891805323 DataSet_02_53
NR2F1 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 0.0416667 -4.58496 0.209855509201645 0.398500421360658 DataSet_04_061
NR2F1 SMARCB1 shRNA Liver SK-Hep1 0.630963 -0.664374 0.0336911898 0.9601744 DataSet_03_313
NR2F1 YBX1 siRNA Prostate LNCaP 0.65027 -0.620889 1.892172e-04 5.323445e-03 DataSet_03_322
NR2F1 EZH2 knockdown Uterus Ishikawa (ISK) cell 0.595979 -0.746667 - - DataSet_03_324
NR2F1 SMARCA4 siRNA Colon HCT116 1.84817 0.886095 4.517508e-03 0.1301247 DataSet_03_302
NR2F1 ELF3 CRISPR Bile_duct HBDEC2 4.20096 2.07072 6.946682e-07 9.728156e-05 DataSet_03_304
NR2F1 SNAI2 shRNA Pancreas pancreatic cancer stem cells 0.546335 -0.872142 6.985723e-02 0.6510154 DataSet_03_306
NR2F1 SNAI2 shRNA Pancreas KLM1 1.57256 0.653115 3.536568e-01 0.66661906 DataSet_03_307
NR2F1 INO80 siRNA Muscle RD 0.524406 -0.931244 - - DataSet_03_344
NR2F1 BCL3 siRNA Central_nervous_system U87 0.558749 -0.839728 7.905244e-09 3.844793e-06 DataSet_03_336
NR2F1 ARID3B CRISPR Colon HCT15 0.59392 -0.75166 - - DataSet_03_335
NR2F1 TET1 CRISPR Mammary_gland MDA-MB-231 1.62889 0.703891 3.447606e-01 5.633328e-01 DataSet_03_347
NR2F1 ZFX siRNA Mammary_gland MCF7 0.4559 -1.13321 5.660186e-02 1.840746e-01 DataSet_03_349
NR2F1 SKI CRISPR Blood HL60 0.65045 -0.620489 6.316306e-02 0.405832852 DataSet_03_351
NR2F1 ETV5 knockdown Colon HT29 1.60958 0.68668 7.715024e-02 0.292264353 DataSet_03_353
NR2F1 TET1 CRISPR Mammary_gland Hs578T 0.534481 -0.903789 4.122235e-02 1.265262e-01 DataSet_03_355
NR2F1 TP53 CRISPR Brain U5-NPC 1.60313 0.680894 2.137929e-01 3.464863e-01 DataSet_03_358
NR2F1 ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 4.53234 2.18026 1.070819e-01 1.753386e-01 DataSet_03_362
NR2F1 MYC siRNA Peripheral_blood T lymphocyte 0.417447 -1.26033 6.072135e-01 0.802576212 DataSet_03_363
NR2F1 EP300 shRNA Mammary_gland MCF10AT 12.1774 3.60614 2.292155e-04 0.014110412 DataSet_03_364
NR2F1 ZFP36L1 siRNA Urinary_bladder J82 3.77778 1.91754 - - DataSet_03_371
NR2F1 SMARCA2 shRNA Lung NCI-H1944 2.18636 1.12853 2.763398e-02 3.165204e-01 DataSet_03_377
NR2F1 DDX5 shRNA Stomach HGC-27 1.69059 0.75753 - - DataSet_03_379
NR2F1 YY1 shRNA Brain GSC3028 0.64459 -0.633545 - - DataSet_03_386
NR2F1 TRIM8 siRNA Mammary_gland MCF7 1.52777 0.611426 2.001264e-02 0.0833299146 DataSet_03_388
NR2F1 NFKBIA shRNA Bone_marrow U2OS 0.33899 -1.56068 2.997403e-01 0.87005461 DataSet_03_389
NR2F1 ILF2 siRNA Stomach SGC-7901 2.27632 1.1867 0.0144361348 0.06095414 DataSet_03_393
NR2F1 ASXL1 CRISPR Embryo iPSC 2.09326 1.06575 0.0217322144 0.8037087 DataSet_03_394
NR2F1 IKZF2 CRISPR Lymph CAR T Cell 0.666555 -0.585204 9.278966e-01 0.999939484 DataSet_03_397
NR2F1 CDK7 shRNA Bone_marrow D458 0.20442 -2.29039 2.188220e-03 0.09724650 DataSet_03_404
NR2F1 TFAP2A knockout Embryo H9 3.52358 1.81704 5.438261e-04 0.02247106 DataSet_03_405
NR2F1 SIRT1 siRNA Pancreas PANC1 0.246142 -2.02244 2.385699e-05 0.007991191 DataSet_03_410
NR2F1 NFATC2 shRNA Haematopoietic_and_lymphoid_tissue THP-1 2.0566 1.04026 1.737530e-03 0.017444801 DataSet_03_418
NR2F1 FOXK2 shRNA Ovary OVCAR-5 7.04762 2.81714 1.531136e-02 0.10672857 DataSet_03_419
NR2F1 MAEL CRISPR Liver Alexander cells 5.5 2.45943 - - DataSet_03_423
NR2F1 FOXP3 CRISPR Peripheral_blood Naive Treg 0.126316 -2.98489 6.397981e-01 0.827599777 DataSet_03_427
NR2F1 STAT3 siRNA Peripheral_blood Monocyte-derived M-CSF macrophages 3.25 1.70044 0.3995885729 1 DataSet_03_430
NR2F1 USP7 shRNA Skin xenograft cells 0.511597 -0.96692 0.26950821 0.4348960 DataSet_03_431
NR2F1 SUFU shRNA Mammary_gland HCC1954 cells 0.0543767 -4.20087 0.0018852668 0.2904148 DataSet_03_437
NR2F1 CIC knockout Brain Immortalized Astrocyte Cells 0.497259 -1.00793 2.205324e-03 8.802385e-02 DataSet_03_438
NR2F1 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.611111 -0.710493 9.707399e-01 1.00000000 DataSet_03_439
NR2F1 SETDB1 shRNA Colon HCT116 0.40736 -1.29562 - - DataSet_03_440
NR2F1 PHF14 siRNA Mammary_gland MDA-MB-231 1.79422 0.843355 0.0338552815 0.3841333 DataSet_03_443
NR2F1 RELB CRISPR Colon SW480 3.01681 1.59302 1.256026e-02 8.872931e-02 DataSet_03_449
NR2F1 CBX2 siRNA Mammary_gland MCF7 1.99318 0.995074 9.409917e-04 0.0053716346 DataSet_03_451
NR2F1 ZFP36L1 CRISPR Lung NCI-H1876 0.512098 -0.965509 4.843365e-01 0.992381486 DataSet_03_454
NR2F1 SMARCA2 shRNA Lung HCC2302 4.95856 2.30992 2.628401e-06 6.338374e-06 DataSet_03_455
NR2F1 STAT3 shRNA Liver HepG2 1.84291 0.881988 1.572612e-02 0.1918281576 DataSet_03_465
NR2F1 EZH2 siRNA Prostate LNCaP 0.451876 -1.146 - - DataSet_03_472
Regulation Region
 
T(co)Fs that significantly regulate POLR2G by the evidences of both expression and ChIP-seq/motif
Expression Atlas of NR2F1
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines