Gene Overview
Target Gene: PRUNE2
NCBI Official Symbol: PRUNE2
Entrez ID: 158471
Ensembl ID: ENSG00000106772
Gene Full Name: prune homolog 2 with BCH domain
Strand: -
Gene Locus: 9q21.2
External Links:

PRUNE2 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate PRUNE2   
T(co)Fs that Repress PRUNE2
The Intensity of the Gene Regulated by T(co)Fs:
PRUNE2-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
PRUNE2 FOXA1 shRNA Prostate 22RV1 0.53268 -0.90866 - - DataSet_01_105
PRUNE2 HOXA1 siRNA Lung_fibroblast IMR-90 0.59219 -0.75587 0.26364 0.55308 DataSet_01_110
PRUNE2 ID1 siRNA Lung A549 1.70238 0.76755 0.07944 0.28443 DataSet_01_117
PRUNE2 FOXM1 siRNA Central_nervous_system U87 5.03443 2.33183 - - DataSet_01_122
PRUNE2 REST siRNA Uterus Smooth muscle cells 1.6628 0.73362 0.13429 0.99996 DataSet_01_136
PRUNE2 IKZF2 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 2.41958 1.27476 0.0184 0.40811 DataSet_01_137
PRUNE2 IKZF1 shRNA Haematopoietic_and_lymphoid_tissue JURKAT 1.61726 0.69356 0.239 0.99993 DataSet_01_138
PRUNE2 HSF1 shRNA Skin A375 0.5947 -0.74977 0.02311 0.11526 DataSet_01_155
PRUNE2 ETV1 shRNA Prostate LNCaP 0.53825 -0.89365 1.19051e-12 6.2022e-10 DataSet_01_161
PRUNE2 HOXB7 siRNA Pancreas Capan-1 0.49811 -1.00547 0.00472 0.41142 DataSet_01_170
PRUNE2 FOSL1 siRNA Mammary_gland BT549 0.60574 -0.72323 0.00023 0.01517 DataSet_01_171
PRUNE2 TCF4 siRNA Autonomic_ganglia SH-SY5Y 0.49493 -1.0147 0.03819 0.1566 DataSet_01_185
PRUNE2 GABPA shRNA Prostate C4-2B 2265.71 11.1458 0.24432 0.43989 DataSet_01_190
PRUNE2 GABPA shRNA Prostate LNCaP 1353.39 10.4024 0.46794 0.7048 DataSet_01_191
PRUNE2 GATA2 siRNA Prostate LNCaP 0.17787 -2.49109 0.00023 0.00192 DataSet_01_193
PRUNE2 CREB1 shRNA Parotid_gland H3118 MEC 2.29032 1.19555 0.6721 0.87107 DataSet_01_194
PRUNE2 TP63 siRNA Head_and_neck SCC-1 0.64686 -0.62848 - - DataSet_01_198
PRUNE2 MITF shRNA Skin COLO829 2.0687 1.04872 0.22707 0.43958 DataSet_01_207
PRUNE2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly10 0.60496 -0.72508 - - DataSet_01_208
PRUNE2 FOXP1 siRNA Haematopoietic_and_lymphoid_tissue OCI-Ly1 0.4023 -1.31365 - - DataSet_01_209
PRUNE2 EGR3 shRNA Prostate M12 0.6527 -0.61552 0.02941 0.18279 DataSet_01_212
PRUNE2 LIN28A siRNA Embryo H9 1.73686 0.79648 0.00858 0.04516 DataSet_01_215
PRUNE2 ERG siRNA Prostate VCaP 1.84878 0.88658 1.87428e-05 0.00143 DataSet_01_216
PRUNE2 SNAI2 shRNA Skin Primary human keratinocytes 0.62466 -0.67885 0.11889 0.23407 DataSet_01_225
PRUNE2 ESR2 siRNA Mammary_gland BT549 3.4066 1.76833 1.42234e-09 4.3735e-06 DataSet_01_229
PRUNE2 FOXA1 siRNA Prostate LNCaP 0.13566 -2.88189 4.38828e-07 0.00113 DataSet_01_233
PRUNE2 FOXP1 siRNA Prostate LNCaP 0.63422 -0.65694 0.01104 0.2646 DataSet_01_234
PRUNE2 AR shRNA Prostate CWR22Pc 1.53642 0.61958 0.00472 0.03876 DataSet_01_278
PRUNE2 ZIC5 siRNA Skin SK-MEL-28 0.429 -1.22096 - - DataSet_01_285
PRUNE2 TFAP4 siRNA Brain BE(2)-C 0.12843 -2.96097 0.24874 0.51625 DataSet_01_295
PRUNE2 MYCN siRNA Brain BE(2)-C 1.98903 0.99207 0.79408 1 DataSet_01_296
PRUNE2 OVOL2 siRNA Corneal_epithelial Corneal epithelial cells 0.60552 -0.72376 0.01241 0.25163 DataSet_01_313
PRUNE2 ZNF25 siRNA Bone_marrow hMSC-TERT4 1.79704 0.84563 0.00248 0.18115 DataSet_01_319
PRUNE2 HNF4G shRNA Prostate 22RV1 0.59248 -0.75517 8.81442e-11 4.22695e-07 DataSet_01_320
PRUNE2 KLF7 siRNA Embryo HCE 0.61529 -0.70066 0.02427 0.99985 DataSet_01_342
PRUNE2 ARID1A shRNA Uterus iEEC16 0.53702 -0.89696 - - DataSet_01_345
PRUNE2 RBFOX2 shRNA Liver HepG2 11 3.45943 0.02057 0.65168 DataSet_02_101
PRUNE2 HDGF shRNA Liver HepG2 0.26667 -1.90689 0.24136 0.41855 DataSet_02_104
PRUNE2 U2AF2 shRNA Liver HepG2 14 3.80735 0.42952 0.57501 DataSet_02_105
PRUNE2 TAF15 shRNA Liver HepG2 1.6 0.67807 0.48622 0.55783 DataSet_02_106
PRUNE2 BCLAF1 shRNA Liver HepG2 3.55556 1.83007 0.24765 0.36602 DataSet_02_112
PRUNE2 U2AF2 shRNA Liver HepG2 5 2.32193 0.45032 0.59289 DataSet_02_113
PRUNE2 XRCC5 shRNA Liver HepG2 2 1 0.07562 0.24392 DataSet_02_114
PRUNE2 PCBP1 shRNA Liver HepG2 3.2 1.67807 0.09103 0.14646 DataSet_02_115
PRUNE2 RBM25 shRNA Liver HepG2 3 1.58496 0.24921 0.3462 DataSet_02_119
PRUNE2 EWSR1 shRNA Liver HepG2 0.03333 -4.90689 0.10399 0.20712 DataSet_02_122
PRUNE2 PCBP2 shRNA Liver HepG2 5 2.32193 0.47039 0.63085 DataSet_02_123
PRUNE2 FUS shRNA Liver HepG2 13 3.70044 0.05011 0.17509 DataSet_02_124
PRUNE2 HNRNPLL shRNA Liver HepG2 4.7 2.23266 0.09884 0.15938 DataSet_02_125
PRUNE2 SRSF3 shRNA Liver HepG2 1.8 0.848 0.32262 0.48046 DataSet_02_127
PRUNE2 POLR2G shRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.848 0.31792 0.78157 DataSet_02_130
PRUNE2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.28 -1.8365 0.01598 0.05785 DataSet_02_131
PRUNE2 AGO2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.16667 -2.58496 0.02395 0.13535 DataSet_02_132
PRUNE2 RBM17 shRNA Haematopoietic_and_lymphoid_tissue K562 0.44444 -1.16993 0.77058 0.89592 DataSet_02_138
PRUNE2 RBFOX2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.13793 1.09622 0.06473 0.47931 DataSet_02_139
PRUNE2 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 4 2 0.04534 0.23479 DataSet_02_140
PRUNE2 BCLAF1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.33333 2.11548 0.69839 0.81628 DataSet_02_142
PRUNE2 PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.11111 1.078 0.71525 0.8488 DataSet_02_144
PRUNE2 DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 2.08 1.05658 0.89524 0.96729 DataSet_02_145
PRUNE2 CCAR2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.4 1.26303 0.02429 0.47274 DataSet_02_146
PRUNE2 FIP1L1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.06667 -3.90689 0.14364 0.27754 DataSet_02_147
PRUNE2 ILF3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.48276 -1.05063 0.96938 0.99601 DataSet_02_148
PRUNE2 NONO shRNA Haematopoietic_and_lymphoid_tissue K562 0.48 -1.05889 0.19895 0.39846 DataSet_02_149
PRUNE2 SAFB2 shRNA Haematopoietic_and_lymphoid_tissue K562 2.91667 1.54432 0.08918 0.51958 DataSet_02_150
PRUNE2 RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.2 -2.32193 0.00498 0.23644 DataSet_02_151
PRUNE2 YBX3 shRNA Haematopoietic_and_lymphoid_tissue K562 0.06897 -3.85798 0.01999 0.42286 DataSet_02_153
PRUNE2 FUS shRNA Haematopoietic_and_lymphoid_tissue K562 9.2 3.20163 0.0026 0.22733 DataSet_02_155
PRUNE2 HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.24 -2.05889 0.03446 0.51515 DataSet_02_156
PRUNE2 GTF2F1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.42105 1.27563 0.18039 0.99879 DataSet_02_157
PRUNE2 PSIP1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.80964 0.87383 DataSet_02_158
PRUNE2 XRCC5 shRNA Haematopoietic_and_lymphoid_tissue K562 1.89474 0.922 0.28309 0.78532 DataSet_02_159
PRUNE2 SUB1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.10526 1.074 0.31955 0.84376 DataSet_02_161
PRUNE2 AGO1 shRNA Haematopoietic_and_lymphoid_tissue K562 4.8 2.26303 0.21434 0.675 DataSet_02_162
PRUNE2 TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 4.7 2.23266 0.05941 0.29584 DataSet_02_163
PRUNE2 SSB shRNA Haematopoietic_and_lymphoid_tissue K562 5.6 2.48543 0.00878 0.20269 DataSet_02_164
PRUNE2 U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.62985 0.76078 DataSet_02_165
PRUNE2 RBM25 shRNA Haematopoietic_and_lymphoid_tissue K562 1.75 0.80735 0.04181 0.22613 DataSet_02_166
PRUNE2 EWSR1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.52632 -0.926 0.70262 0.83945 DataSet_02_167
PRUNE2 TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 4.66667 2.22239 0.00701 0.05005 DataSet_02_169
PRUNE2 U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 6.125 2.61471 0.04747 0.13204 DataSet_02_170
PRUNE2 RBM15 shRNA Haematopoietic_and_lymphoid_tissue K562 3.25 1.70044 0.01886 0.2135 DataSet_02_171
PRUNE2 NFE2L2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.625 -0.67807 0.57184 1 DataSet_02_174
PRUNE2 LMNA siRNA Haematopoietic_and_lymphoid_tissue K562 1.65 0.72247 0.2855 1 DataSet_02_175
PRUNE2 CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 3.15789 1.65896 0.47796 1 DataSet_02_176
PRUNE2 TBL1XR1 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.95746 1 DataSet_02_178
PRUNE2 VEZF1 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.83689 1 DataSet_02_179
PRUNE2 ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 0.08333 -3.58496 0.02263 1 DataSet_02_180
PRUNE2 ZMIZ1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.02 -5.64386 0.04825 1 DataSet_02_181
PRUNE2 STAT5A siRNA Haematopoietic_and_lymphoid_tissue K562 0.4375 -1.19265 0.84548 1 DataSet_02_182
PRUNE2 MAFK siRNA Haematopoietic_and_lymphoid_tissue K562 0.5614 -0.83289 0.27362 1 DataSet_02_183
PRUNE2 CTCF siRNA Haematopoietic_and_lymphoid_tissue K562 0.26087 -1.9386 0.01778 1 DataSet_02_185
PRUNE2 BHLHE40 siRNA Haematopoietic_and_lymphoid_tissue K562 0.15789 -2.66297 0.00377 1 DataSet_02_186
PRUNE2 CHD1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.21053 -2.24793 0.01614 1 DataSet_02_187
PRUNE2 BACH1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.52632 1.33703 0.79904 1 DataSet_02_188
PRUNE2 MAFG siRNA Haematopoietic_and_lymphoid_tissue K562 2.78947 1.47999 0.65771 1 DataSet_02_189
PRUNE2 RAD21 siRNA Haematopoietic_and_lymphoid_tissue K562 0.57971 -0.7866 0.08785 1 DataSet_02_190
PRUNE2 MAX siRNA Haematopoietic_and_lymphoid_tissue K562 1.57895 0.65896 0.4236 1 DataSet_02_192
PRUNE2 ARID3A siRNA Haematopoietic_and_lymphoid_tissue K562 0.21053 -2.24793 0.05335 1 DataSet_02_193
PRUNE2 TCP1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.35 1.74416 0.16595 1 DataSet_02_194
PRUNE2 LMNB1 siRNA Haematopoietic_and_lymphoid_tissue K562 3.15789 1.65896 0.38678 1 DataSet_02_195
PRUNE2 CHD2 siRNA Haematopoietic_and_lymphoid_tissue K562 0.42105 -1.24793 0.01912 0.13144 DataSet_02_196
PRUNE2 CDAN1 siRNA Haematopoietic_and_lymphoid_tissue K562 2.68421 1.4245 0.42489 1 DataSet_02_197
PRUNE2 UBTF siRNA Haematopoietic_and_lymphoid_tissue K562 0.02 -5.64386 0.04909 1 DataSet_02_198
PRUNE2 E2F4 siRNA Haematopoietic_and_lymphoid_tissue K562 3.45 1.7866 0.13876 1 DataSet_02_200
PRUNE2 TAL1 siRNA Haematopoietic_and_lymphoid_tissue K562 2 1 0.27837 1 DataSet_02_201
PRUNE2 ZNF384 siRNA Haematopoietic_and_lymphoid_tissue K562 1.8 0.848 1 1 DataSet_02_203
PRUNE2 RCOR1 siRNA Haematopoietic_and_lymphoid_tissue K562 1.79167 0.8413 0.21043 1 DataSet_02_204
PRUNE2 E2F6 siRNA Haematopoietic_and_lymphoid_tissue K562 4.15789 2.05585 0.32257 1 DataSet_02_205
PRUNE2 ATOH8 siRNA Umbilical_vein HUVEC 0.567729 -0.816727 0.0174102884429103 0.505388466797885 DataSet_03_019
PRUNE2 BCL6 siRNA Lymph OCI-Ly7 DLBCL 0.601476 -0.733422 0.154862035814489 0.789148762243936 DataSet_03_025
PRUNE2 CEBPB siRNA Embryo hESC 1.55713 0.638888 0.0718943785417458 0.418427950807897 DataSet_03_049
PRUNE2 FOXO1 siRNA Skin primary human dermal lymphatic endothelial cells 3.54206 1.82459 - - DataSet_03_096
PRUNE2 GATA2 siRNA Uterus Decidual stromal cells 0.513967 -0.960252 0.147278890158884 0.766433471633348 DataSet_03_100
PRUNE2 GATA2 siRNA Lymph Lymphatic endothelial cells 1.52504 0.608847 3.26689416560231e-05 0.000384652174413493 DataSet_03_101
PRUNE2 GATA4 siRNA Stomach AGS 0.539192 -0.891129 0.206769474909793 0.832436764001732 DataSet_03_105
PRUNE2 GATA6 siRNA Stomach AGS 0.481465 -1.0545 0.130604168646965 0.626408255160584 DataSet_03_108
PRUNE2 GATA6 siRNA Stomach KatoIII 0.31287 -1.67637 0.0756528046436334 0.588244698225451 DataSet_03_109
PRUNE2 HINFP siRNA Bone_marrow hTERT-RPE1 1.57997 0.659896 0.00155160318505991 0.0846590903014489 DataSet_03_122
PRUNE2 IRF4 siRNA Skin Cutaneous T cell lymphoma HuT-102 cells 1.62557 0.700943 0.248791730039711 0.999948959532916 DataSet_03_134
PRUNE2 MEF2D shRNA Liver HuH7 1.60337 0.68111 - - DataSet_03_162
PRUNE2 MEF2D siRNA Liver HuH7 1.62075 0.696666 - - DataSet_03_163
PRUNE2 MYB siRNA Cord_Blood CD34+ progenitor cells 2.84401 1.50793 - - DataSet_03_170
PRUNE2 MYC siRNA Central_nervous_system DAOY M2.1 1.52523 0.609023 2.14113076844889e-05 9.37069256078428e-05 DataSet_03_178
PRUNE2 MYCN siRNA Brain BE(2)C cells 1.96646 0.9756 - - DataSet_03_187
PRUNE2 PHB shRNA Embryo Embryonic stem cells (ESCs) 4.6957 2.23134 1.08700732122141e-05 0.000384626528448523 DataSet_03_211
PRUNE2 SOX2 siRNA Embryo 2102Ep 0.448321 -1.1574 2.41721459787795e-05 0.00126177518056494 DataSet_03_242
PRUNE2 SOX2 siRNA Embryo NTera-2 0.599373 -0.738475 6.17766623838283e-05 0.00497340808449675 DataSet_03_243
PRUNE2 SP1 siRNA Ovary OVSAYO 0.525494 -0.928253 0.0431392322538187 0.254036860026829 DataSet_03_251
PRUNE2 SRF siRNA Prostate LNCaP 1.84254 0.881694 0.0211626420271418 0.105634088301138 DataSet_03_254
PRUNE2 STAT3 CRISPR Embryo hESC 2.18441 1.12724 0.0666820899348134 0.145300959129786 DataSet_03_258
PRUNE2 CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 6.92308 2.79141 0.00139323441726782 0.0203807957976271 DataSet_04_004
PRUNE2 FUBP3 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.409091 -1.28951 0.517219143684842 0.906985037885136 DataSet_04_011
PRUNE2 MECP2 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.58333 1.36923 0.185521746740885 0.825033112535891 DataSet_04_013
PRUNE2 SMAD2 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.52941 0.612977 0.241319779929558 0.390484986563139 DataSet_04_018
PRUNE2 SMAD4 CRISPR Haematopoietic_and_lymphoid_tissue K562 3.83333 1.9386 0.118222984722609 0.277560671827178 DataSet_04_019
PRUNE2 ZNF574 CRISPR Haematopoietic_and_lymphoid_tissue K562 3 1.58496 0.0721467600713585 0.201642927151861 DataSet_04_023
PRUNE2 ANXA2 CRISPR Liver HepG2 1.83333 0.874469 0.288620488325958 0.765623318756345 DataSet_04_024
PRUNE2 CIZ1 CRISPR Liver HepG2 0.481481 -1.05445 0.340405351555996 0.570949639772037 DataSet_04_026
PRUNE2 CTCF CRISPR Liver HepG2 3.33333 1.73697 0.0123172961445457 0.785672071979127 DataSet_04_027
PRUNE2 SMAD5 CRISPR Liver HepG2 1.66667 0.736966 0.114615814688338 0.51037434906441 DataSet_04_036
PRUNE2 ZNF574 CRISPR Liver HepG2 0.444444 -1.16992 0.0661095520415515 0.165959586225372 DataSet_04_041
PRUNE2 APTX CRISPR Liver HepG2 3.33333 1.73697 0.217355406036995 0.824268978173362 DataSet_04_069
PRUNE2 CHCHD3 CRISPR Liver HepG2 11 3.45943 0.485692179743242 0.767495906783103 DataSet_04_067
PRUNE2 DNMT3B CRISPR Liver HepG2 2 1 0.631491537909388 0.837106188214253 DataSet_04_044
PRUNE2 PAN2 CRISPR Liver HepG2 1.71429 0.777608 0.598248704437398 0.754570081550815 DataSet_04_066
PRUNE2 RIOK2 CRISPR Liver HepG2 0.5 -1 0.940099658256267 1 DataSet_04_070
PRUNE2 PRPF6 shRNA Liver HepG2 16 4 0.265134012525647 0.478435268107016 DataSet_04_056
PRUNE2 NPM1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.75 1.45943 0.113684525004123 0.266073272428151 DataSet_04_046
PRUNE2 SEPT11 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.66667 0.736966 0.653660254546875 1 DataSet_04_077
PRUNE2 SMG5 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.11111 1.078 0.396760390295185 0.748493525590981 DataSet_04_073
PRUNE2 SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.33333 1.22239 0.427621548522948 0.747069062654746 DataSet_04_075
PRUNE2 SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 2.88889 1.53051 0.222761535696893 0.374954448303922 DataSet_04_049
PRUNE2 CITED2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 3.40909 1.76939 0.281541899706533 0.546397587684769 DataSet_02_38
PRUNE2 ERF CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.136364 -2.87447 0.378197167348228 0.557349438307065 DataSet_02_34
PRUNE2 HMGN3 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.590909 -0.758992 0.776649648220122 0.954518101686839 DataSet_02_45
PRUNE2 LDB1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.63636 0.710493 0.470801129203039 0.650849283303049 DataSet_02_35
PRUNE2 SMARCA4 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.636364 -0.652077 0.720352713025874 0.832909517121502 DataSet_02_47
PRUNE2 SNW1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.214286 -2.22239 0.593240414034404 0.890042769452059 DataSet_02_49
PRUNE2 TBL1XR1 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.136364 -2.87447 0.371087678426804 0.562097320732891 DataSet_02_43
PRUNE2 TEAD2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 1.54545 0.628031 0.587475766462733 0.734626606238907 DataSet_02_33
PRUNE2 ABT1 shRNA Haematopoietic_and_lymphoid_tissue K562 38 5.24793 0.0715277208094463 0.170035087048319 DataSet_04_060
PRUNE2 CNOT7 shRNA Haematopoietic_and_lymphoid_tissue K562 2.38889 1.25634 0.279512133928214 0.478698039335013 DataSet_04_061
PRUNE2 DDX1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.107143 -3.22239 0.254241061959638 0.689377245123363 DataSet_04_063
PRUNE2 PRPF6 shRNA Haematopoietic_and_lymphoid_tissue K562 3.63158 1.8606 0.0839010905046349 0.4239536501157 DataSet_04_065
PRUNE2 UBE2L3 shRNA Haematopoietic_and_lymphoid_tissue K562 3.8 1.926 0.122422104928038 0.339193379910445 DataSet_04_062
PRUNE2 ELF3 CRISPR Bile_duct HBDEC2 5.02931 2.33036 5.552007e-06 2.574609e-04 DataSet_03_304
PRUNE2 HDAC5 siRNA Liver human hepatocytes 0.455785 -1.13357 9.275340e-06 4.083102e-04 DataSet_03_346
PRUNE2 SNAI2 shRNA Pancreas pancreatic cancer stem cells 1.69771 0.763588 3.947631e-02 0.6330193 DataSet_03_306
PRUNE2 SNAI2 shRNA Pancreas KLM1 0.20307 -2.29995 7.940619e-03 0.15733311 DataSet_03_307
PRUNE2 EZH2 siRNA Prostate LNCaP 1.85743 0.893312 0.0021403313 0.9997152 DataSet_03_328
PRUNE2 EZH2 siRNA Prostate LNCaP 1.85743 0.893312 0.0021403313 0.9997152 DataSet_03_330
PRUNE2 TET1 CRISPR Mammary_gland MDA-MB-231 8.22379 3.0398 6.235537e-01 7.725512e-01 DataSet_03_347
PRUNE2 ZFX siRNA Mammary_gland MCF7 1.90176 0.927332 5.957793e-02 1.906728e-01 DataSet_03_349
PRUNE2 TET1 CRISPR Mammary_gland Hs578T 1.72644 0.787799 2.123927e-03 1.818230e-02 DataSet_03_355
PRUNE2 TP53 CRISPR Brain U5-NPC 2.04604 1.03284 1.169782e-01 2.525739e-01 DataSet_03_358
PRUNE2 NCOA3 siRNA Mammary_gland MDA-MB-231 0.556094 -0.846601 6.289605e-01 0.9450353 DataSet_03_361
PRUNE2 EP300 shRNA Mammary_gland MCF10AT 0.479339 -1.06088 1.488747e-02 0.089058364 DataSet_03_364
PRUNE2 TP53 knockout Stomach SNU1 1.8572 0.893125 0.0204009174 0.9301241 DataSet_03_365
PRUNE2 DNMT3A knockout Embryo_kidney HEK293T 1.74426 0.802614 - - DataSet_03_369
PRUNE2 TPR shRNA Bone_marrow U2OS 0.593203 -0.753403 1.926776e-02 2.042445e-01 DataSet_03_370
PRUNE2 ZFP36L1 siRNA Urinary_bladder J82 2.66667 1.41504 - - DataSet_03_371
PRUNE2 GLI1 siRNA Skeletal_muscle RMS13 3.34366 1.74143 1.058621e-03 0.021733707 DataSet_03_375
PRUNE2 EZH2 CRISPR Ovary SKOV3 0.638037 -0.648288 8.910170e-02 0.2575307958 DataSet_03_378
PRUNE2 KAT6A CRISPR Haematopoietic_and_lymphoid_tissue MOLM-13 2.24302 1.16544 0.0292768636 0.8388073 DataSet_03_387
PRUNE2 TRIM8 siRNA Mammary_gland MCF7 3.875 1.9542 9.308077e-02 0.2409181038 DataSet_03_388
PRUNE2 NFKBIA shRNA Bone_marrow U2OS 0.212021 -2.23772 9.203326e-01 0.96669509 DataSet_03_389
PRUNE2 ILF2 siRNA Stomach SGC-7901 0.409091 -1.28951 0.2252974889 0.41275218 DataSet_03_393
PRUNE2 ASXL1 CRISPR Embryo iPSC 1.62301 0.698668 0.1204364939 0.8117897 DataSet_03_394
PRUNE2 BMI1 shRNA Bile_duct QBC-939 4.28571 2.09953 5.499714e-03 0.0248002108 DataSet_03_395
PRUNE2 IKZF2 CRISPR Lymph CAR T Cell 1.93626 0.953274 5.759503e-02 0.441115363 DataSet_03_397
PRUNE2 RELA CRISPR Brain T30 0.031252 -4.99991 0.2430090818 0.8400824 DataSet_03_399
PRUNE2 HMGA1 shRNA Bile_duct HUCCT1 4.70085 2.23292 1.432895e-03 0.045170038 DataSet_03_400
PRUNE2 SUMO1 CRISPR Bone_marrow U2OS 1.98578 0.989707 3.719268e-04 7.706051e-03 DataSet_03_401
PRUNE2 EHF shRNA Stomach MKN7 0.00163557 -9.25599 - - DataSet_03_402
PRUNE2 CDK7 shRNA Bone_marrow D458 64.4 6.00899 6.436704e-04 0.06805857 DataSet_03_404
PRUNE2 TFAP2A knockout Embryo H9 2.17889 1.12359 2.090163e-03 0.03537905 DataSet_03_405
PRUNE2 CHD1 shRNA Prostate LNCaP 0.648715 -0.624344 2.857185e-02 3.778608e-01 DataSet_03_407
PRUNE2 STRAP knockout Nerve SK-N-AS 0.0230054 -5.44188 - - DataSet_03_409
PRUNE2 E2F6 shRNA Liver HuH7 0.370364 -1.43298 - - DataSet_03_412
PRUNE2 ZKSCAN3 CRISPR Colon HCT116 1.57303 0.65355 1.808733e-01 0.613836115 DataSet_03_415
PRUNE2 FOXK2 shRNA Ovary OVCAR-5 0.5 -1 2.290375e-01 0.45139695 DataSet_03_419
PRUNE2 BRD4 CRISPR Lymph CD8+ T cells 0.545455 -0.874469 - - DataSet_03_420
PRUNE2 FOXP3 CRISPR Peripheral_blood Naive Treg 1.95727 0.968839 7.936010e-02 0.378557251 DataSet_03_427
PRUNE2 USP7 shRNA Skin xenograft cells 0.312645 -1.6774 0.29171246 0.4390460 DataSet_03_431
PRUNE2 PLAG1 shRNA Cord_blood Lin-CD34+ HSPCs 0.176856 -2.49935 - - DataSet_03_432
PRUNE2 NFE2L1 knockout Lung A549 0.264554 -1.91836 8.336429e-01 9.984904e-01 DataSet_03_433
PRUNE2 POU2AF1 CRISPR Haematopoietic_and_lymphoid_tissue OCI-Ly7 3.493 1.80447 8.541197e-03 0.289074999 DataSet_03_434
PRUNE2 POU2AF1 CRISPR Lymph SUDHL4 19.3407 4.27357 5.039998e-04 0.009961842 DataSet_03_435
PRUNE2 SUFU shRNA Mammary_gland HCC1954 cells 0.556962 -0.844349 0.0440765801 0.4956511 DataSet_03_437
PRUNE2 CIC knockout Brain Immortalized Astrocyte Cells 5.68949 2.5083 6.019265e-02 4.189029e-01 DataSet_03_438
PRUNE2 FOXA2 CRISPR Liver iPSCs-derived progenitors and mature hepatocytes 0.589377 -0.762738 6.682564e-01 0.98900505 DataSet_03_439
PRUNE2 SETDB1 shRNA Colon HCT116 0.233101 -2.10097 - - DataSet_03_440
PRUNE2 HMG20A siRNA Mammary_gland MDA-MB-231 2.5 1.32193 0.0329727753 0.2152436 DataSet_03_442
PRUNE2 FOSL1 siRNA Prostate MSKPCa3 0.515905 -0.954822 0.0078315634 0.2972892 DataSet_03_445
PRUNE2 CAMTA1 knockout Embryo_kidney HEK293T 2.04 1.02857 1.388310e-03 0.05694071 DataSet_03_448
PRUNE2 CBX2 siRNA Mammary_gland MCF7 4.05998 2.02147 1.288747e-02 0.0370064563 DataSet_03_451
PRUNE2 SREBF2 siRNA Umbilical_vein HUVEC 1.97177 0.979487 1.442776e-01 5.717527e-01 DataSet_03_457
PRUNE2 ARID1A shRNA Bile_duct MMNK1 0.570997 -0.808444 4.200662e-03 0.061728794 DataSet_03_458
PRUNE2 IRF2 shRNA Cord_Blood CD34+ cells 1.504 0.588805 - - DataSet_03_460
PRUNE2 TXNIP shRNA Cord_Blood CD34+ cells 4.4 2.1375 - - DataSet_03_461
PRUNE2 PARP1 knockout Embryo_kidney HEK293a 1.95946 0.970456 8.042824e-04 3.885622e-03 DataSet_03_464
PRUNE2 SMARCA1 Cas13 Embryo_kidney HEK293T 0.627692 -0.671871 - - DataSet_03_466
PRUNE2 SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.03077 1.02203 - - DataSet_03_467
PRUNE2 LIN28A siRNA Mammary_gland MCF7M 2.06165 1.0438 8.535388e-01 0.9851210 DataSet_03_469
PRUNE2 LIN28A siRNA Mammary_gland MCF7M 2.06165 1.0438 8.535388e-01 0.9851210 DataSet_03_470
PRUNE2 EZH2 siRNA Prostate LNCaP 1.70828 0.772541 - - DataSet_03_472
PRUNE2 CREBBP CRISPR Lymph U2932 6 2.58496 1.075977e-01 1.0000000 DataSet_03_474
Regulation Region
 
T(co)Fs that significantly regulate CDK7 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of PRUNE2
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines